WO2000010592A3 - Medicaments for preventing or reducing scarring - Google Patents

Medicaments for preventing or reducing scarring Download PDF

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Publication number
WO2000010592A3
WO2000010592A3 PCT/GB1999/002634 GB9902634W WO0010592A3 WO 2000010592 A3 WO2000010592 A3 WO 2000010592A3 GB 9902634 W GB9902634 W GB 9902634W WO 0010592 A3 WO0010592 A3 WO 0010592A3
Authority
WO
WIPO (PCT)
Prior art keywords
medicaments
preventing
reducing scarring
scarring
immunomodulator
Prior art date
Application number
PCT/GB1999/002634
Other languages
French (fr)
Other versions
WO2000010592A2 (en
Inventor
Mark William James Ferguson
Salah Chettibi
Original Assignee
Univ Manchester
Mark William James Ferguson
Salah Chettibi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Manchester, Mark William James Ferguson, Salah Chettibi filed Critical Univ Manchester
Priority to AU11686/00A priority Critical patent/AU1168600A/en
Publication of WO2000010592A2 publication Critical patent/WO2000010592A2/en
Publication of WO2000010592A3 publication Critical patent/WO2000010592A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Abstract

Medicaments for use in the prevention or reduction of scarring comprising a therapeutically effective amount of an immunomodulator. Such medicaments are particularly useful for preventing or reducing dermal scarring. The immunomodulator may be Cyclosporin A, FK-506 or guanylhydrazone.
PCT/GB1999/002634 1998-08-22 1999-08-23 Medicaments for preventing or reducing scarring WO2000010592A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU11686/00A AU1168600A (en) 1998-08-22 1999-08-23 Medicaments for preventing or reducing scarring

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9818278.5A GB9818278D0 (en) 1998-08-22 1998-08-22 Compositions
GB9818278.5 1998-08-22

Publications (2)

Publication Number Publication Date
WO2000010592A2 WO2000010592A2 (en) 2000-03-02
WO2000010592A3 true WO2000010592A3 (en) 2000-06-08

Family

ID=10837638

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1999/002634 WO2000010592A2 (en) 1998-08-22 1999-08-23 Medicaments for preventing or reducing scarring

Country Status (3)

Country Link
AU (1) AU1168600A (en)
GB (1) GB9818278D0 (en)
WO (1) WO2000010592A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2011003002A (en) * 2008-09-19 2011-05-31 Cytokine Pharmasciences Inc Guanylhydrazones for treatment of postoperative intestinal inflammation.

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989001772A1 (en) * 1987-09-03 1989-03-09 University Of Georgia Research Foundation, Inc. Ocular cyclosporin composition
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
WO1992008474A2 (en) * 1990-11-20 1992-05-29 The National Heart & Lung Institute Treatment of lung diseases
WO1998013024A2 (en) * 1996-09-27 1998-04-02 Hyal Pharmaceutical Corporation Hyaluronic drug delivery system
WO1998036061A2 (en) * 1997-02-13 1998-08-20 The Victoria University Of Manchester Reducing fibrosis and/or scarring by inhibiting interleukin-6 receptor-mediated activity

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989001772A1 (en) * 1987-09-03 1989-03-09 University Of Georgia Research Foundation, Inc. Ocular cyclosporin composition
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
WO1992008474A2 (en) * 1990-11-20 1992-05-29 The National Heart & Lung Institute Treatment of lung diseases
WO1998013024A2 (en) * 1996-09-27 1998-04-02 Hyal Pharmaceutical Corporation Hyaluronic drug delivery system
WO1998036061A2 (en) * 1997-02-13 1998-08-20 The Victoria University Of Manchester Reducing fibrosis and/or scarring by inhibiting interleukin-6 receptor-mediated activity

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BJORK L ET AL: "Targeted suppression of cytokine production in monocytes but not in T lymphocytes by a tetravalent guanylhydrazone ( CNI - 1493 ).", JOURNAL OF INFECTIOUS DISEASES, (1997 NOV) 176 (5) 1303-12., XP000877272 *
DUNCAN J I ET AL: "TOPICAL CYCLOSPORIN AND T LYMPHOCYTES IN KELOID SCARS.", BR. J. DERMATOL., (1991) 124 (1), 109., XP000877267 *
HUNNINGHAKE G.W. ET AL: "Approaches to the treatment of pulmonary fibrosis.", AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, (1995) 151/3 I (915-918)., XP000877253 *
SAKAMOTO H ET AL: "Immunosuppressive drugs inhibit the production of interleukin - 6 and interleukin-8 in cultured cardiac myxoma cells.", RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY, (1997 JUL) 97 (1) 60-6., XP000877295 *
ZIERHUT M. ET AL: "[Application of ciclosporin-A eye drops in the treatment of third degree chemical burns]. ANWENDUNG VON CICLOSPORIN-A-AUGENTROPFEN BEI DER BEHANDLUNG VON SCHWEREN VERATZUNGEN.", FORTSCHRITTE DER OPHTHALMOLOGIE, (1987) 84/6 (535-539)., XP000877249 *

Also Published As

Publication number Publication date
GB9818278D0 (en) 1998-10-14
AU1168600A (en) 2000-03-14
WO2000010592A2 (en) 2000-03-02

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