WO2000009479A3 - Heterocyclic thioesters or ketones for vision and memory disorders - Google Patents

Heterocyclic thioesters or ketones for vision and memory disorders Download PDF

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Publication number
WO2000009479A3
WO2000009479A3 PCT/US1999/018239 US9918239W WO0009479A3 WO 2000009479 A3 WO2000009479 A3 WO 2000009479A3 US 9918239 W US9918239 W US 9918239W WO 0009479 A3 WO0009479 A3 WO 0009479A3
Authority
WO
WIPO (PCT)
Prior art keywords
vision
ketones
memory disorders
heterocyclic thioesters
thioesters
Prior art date
Application number
PCT/US1999/018239
Other languages
French (fr)
Other versions
WO2000009479A2 (en
Inventor
Douglas T Ross
Hansjorg Sauer
Gregory S Hamilton
Joseph P Steiner
Original Assignee
Guilford Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guilford Pharm Inc filed Critical Guilford Pharm Inc
Priority to AU53971/99A priority Critical patent/AU5397199A/en
Priority to EP99939732A priority patent/EP1104298A2/en
Priority to JP2000564933A priority patent/JP2002522525A/en
Priority to CA002340668A priority patent/CA2340668A1/en
Priority to MXPA01001668A priority patent/MXPA01001668A/en
Publication of WO2000009479A2 publication Critical patent/WO2000009479A2/en
Publication of WO2000009479A3 publication Critical patent/WO2000009479A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using heterocyclic thioesters and ketones.
PCT/US1999/018239 1998-08-14 1999-08-12 Heterocyclic thioesters or ketones for vision and memory disorders WO2000009479A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU53971/99A AU5397199A (en) 1998-08-14 1999-08-12 Heterocyclic thioesters or ketones for vision and memory disorders
EP99939732A EP1104298A2 (en) 1998-08-14 1999-08-12 Heterocyclic thioesters or ketones for vision and memory disorders
JP2000564933A JP2002522525A (en) 1998-08-14 1999-08-12 Heterocyclic thioesters or ketones for vision and memory impairment
CA002340668A CA2340668A1 (en) 1998-08-14 1999-08-12 Heterocyclic thioesters or ketones for vision and memory disorders
MXPA01001668A MXPA01001668A (en) 1998-08-14 1999-08-12 Heterocyclic thioesters or ketones for vision and memory disorders.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/134,424 US6384056B1 (en) 1998-08-14 1998-08-14 Heterocyclic thioesters or ketones for vision and memory disorders
US09/134,424 1998-08-14

Publications (2)

Publication Number Publication Date
WO2000009479A2 WO2000009479A2 (en) 2000-02-24
WO2000009479A3 true WO2000009479A3 (en) 2000-05-18

Family

ID=22463347

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/018239 WO2000009479A2 (en) 1998-08-14 1999-08-12 Heterocyclic thioesters or ketones for vision and memory disorders

Country Status (7)

Country Link
US (1) US6384056B1 (en)
EP (1) EP1104298A2 (en)
JP (1) JP2002522525A (en)
AU (1) AU5397199A (en)
CA (1) CA2340668A1 (en)
MX (1) MXPA01001668A (en)
WO (1) WO2000009479A2 (en)

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US7977385B2 (en) * 2000-03-02 2011-07-12 Numoda Biotechnologies, Inc. Agents for corneal or intrastromal administration to treat or prevent disorders of the eye
US20030199574A1 (en) * 2000-03-02 2003-10-23 Vitreo-Retinal Technologies, Inc. Treatment of ophthalmic disorders using urea and urea derivatives
US20050137124A1 (en) * 2002-08-09 2005-06-23 Vitreo-Retinal Technologies, Inc. A California Corporation Agents for intravitreal administration to treat or prevent disorders of the eye
WO2006086750A1 (en) 2005-02-09 2006-08-17 Macusight, Inc. Liquid formulations for treatment of diseases or conditions
JP5528708B2 (en) 2006-02-09 2014-06-25 参天製薬株式会社 Stable formulations and methods for preparing and using them
US8222271B2 (en) 2006-03-23 2012-07-17 Santen Pharmaceutical Co., Ltd. Formulations and methods for vascular permeability-related diseases or conditions

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Also Published As

Publication number Publication date
US6384056B1 (en) 2002-05-07
EP1104298A2 (en) 2001-06-06
JP2002522525A (en) 2002-07-23
MXPA01001668A (en) 2002-04-08
WO2000009479A2 (en) 2000-02-24
CA2340668A1 (en) 2000-02-24
AU5397199A (en) 2000-03-06

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