WO1999042827A3 - Device for detecting oligonucleotide and/or polynucleotide hybridization - Google Patents
Device for detecting oligonucleotide and/or polynucleotide hybridization Download PDFInfo
- Publication number
- WO1999042827A3 WO1999042827A3 PCT/DE1999/000460 DE9900460W WO9942827A3 WO 1999042827 A3 WO1999042827 A3 WO 1999042827A3 DE 9900460 W DE9900460 W DE 9900460W WO 9942827 A3 WO9942827 A3 WO 9942827A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polynucleotide hybridization
- detecting oligonucleotide
- oligonucleotide
- polynucleotide
- detection
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/405—Concentrating samples by adsorption or absorption
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/22—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
- G01N27/221—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance by investigating the dielectric properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
- G01N29/02—Analysing fluids
- G01N29/036—Analysing fluids by measuring frequency or resonance of acoustic waves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2291/00—Indexing codes associated with group G01N29/00
- G01N2291/02—Indexing codes associated with the analysed material
- G01N2291/025—Change of phase or condition
- G01N2291/0256—Adsorption, desorption, surface mass change, e.g. on biosensors
- G01N2291/0257—Adsorption, desorption, surface mass change, e.g. on biosensors with a layer containing at least one organic compound
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99915484A EP1055004A2 (en) | 1998-02-20 | 1999-02-19 | Device for detecting oligonucleotide and/or polynucleotide hybridization |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1998107339 DE19807339A1 (en) | 1998-02-20 | 1998-02-20 | Sensitive surface for sensor |
DE19807339.9 | 1998-02-20 | ||
DE19807338A DE19807338A1 (en) | 1998-02-20 | 1998-02-20 | Device for detecting nucleic acid hybridization |
DE19807338.0 | 1998-02-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999042827A2 WO1999042827A2 (en) | 1999-08-26 |
WO1999042827A3 true WO1999042827A3 (en) | 1999-10-28 |
Family
ID=26044047
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE1999/000460 WO1999042827A2 (en) | 1998-02-20 | 1999-02-19 | Device for detecting oligonucleotide and/or polynucleotide hybridization |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP1055004A2 (en) |
WO (1) | WO1999042827A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000070345A1 (en) | 1999-05-14 | 2000-11-23 | Iris Bio Technologies | Reversible immobilization of ligands onto metal surfaces, their preparation and use in biochemical applications |
EP1234182A2 (en) * | 1999-06-30 | 2002-08-28 | Iris Bio Technologies | Hybridization of target dna with immobilized nucleic acid analogs |
DE10113355A1 (en) * | 2000-04-28 | 2001-09-13 | Vladimir M Mirsky | Chemical sensor used for the qualitative or quantitative detection of mercury consists of a receptor layer covered by one or more organic layers |
DE10048997A1 (en) * | 2000-09-27 | 2002-04-11 | Santron Ag | Device for the detection of charged macromolecules |
AT413214B (en) * | 2003-01-24 | 2005-12-15 | Sy Lab Vgmbh | MEASUREMENT ARRANGEMENT AND METHOD FOR DETECTING A DNA SEQUENCE |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993020230A1 (en) * | 1992-03-27 | 1993-10-14 | Environmental & Medical Products Ltd | Electrochemical detection of dna hybridisation |
US5653939A (en) * | 1991-11-19 | 1997-08-05 | Massachusetts Institute Of Technology | Optical and electrical methods and apparatus for molecule detection |
WO1999014596A1 (en) * | 1997-09-15 | 1999-03-25 | Ab Sangtec Medical | Capacity affinity sensor |
WO1999027355A1 (en) * | 1997-11-21 | 1999-06-03 | Wolfbeis, Otto, Samuel | Method for producing laterally organized structures on supporting surfaces |
WO1999028047A2 (en) * | 1997-11-29 | 1999-06-10 | Wolfbeis, Otto, Samuel | Artificial surface with predetermined affinity |
DE19901761A1 (en) * | 1999-01-18 | 1999-07-01 | Gerhard Dr Hartwich | Oligonucleotides tagged with photoinducible redox-active unit |
-
1999
- 1999-02-19 WO PCT/DE1999/000460 patent/WO1999042827A2/en not_active Application Discontinuation
- 1999-02-19 EP EP99915484A patent/EP1055004A2/en not_active Withdrawn
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5653939A (en) * | 1991-11-19 | 1997-08-05 | Massachusetts Institute Of Technology | Optical and electrical methods and apparatus for molecule detection |
WO1993020230A1 (en) * | 1992-03-27 | 1993-10-14 | Environmental & Medical Products Ltd | Electrochemical detection of dna hybridisation |
WO1999014596A1 (en) * | 1997-09-15 | 1999-03-25 | Ab Sangtec Medical | Capacity affinity sensor |
WO1999027355A1 (en) * | 1997-11-21 | 1999-06-03 | Wolfbeis, Otto, Samuel | Method for producing laterally organized structures on supporting surfaces |
WO1999028047A2 (en) * | 1997-11-29 | 1999-06-10 | Wolfbeis, Otto, Samuel | Artificial surface with predetermined affinity |
DE19901761A1 (en) * | 1999-01-18 | 1999-07-01 | Gerhard Dr Hartwich | Oligonucleotides tagged with photoinducible redox-active unit |
Non-Patent Citations (7)
Title |
---|
HASHIMOTO K ET AL.: "Novel DNA sensor for electrochemical gene detection", ANALYTICA CHIMICA ACTA, vol. 286, 1994, pages 219 - 224, XP002113742 * |
MARRAZZA G ET AL.: "Disposable DNA electrochemical sensor for hybridization detection", BIOSENSORS & BIOELECTRONICS, vol. 14, 1999, pages 43 - 51, XP002113746 * |
MIKKELSEN S R: "Electrochemical sensors for DNA sequence detection", ELECTROANALYSIS, vol. 8, no. 1, 1996, pages 15 - 19, XP002113745 * |
SCHLENOFF J B ET AL.: "Stability and self-exchange in alkanethiol monolayers", THE JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 117, 1995, pages 12528 - 12536, XP002113743 * |
TARLOV M J: "Electron-transfer reaction of cytochrome c adsorbed on carboxylic acid terminated alkanethiol monolayer electrodes", THE JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 113, 1991, pages 1847 - 1849, XP002113744 * |
WANG J ET AL.: "Nucleic-acid immobilization, recognition and detection at chronopotentiometric DNA chips", BIOSENSORS & BIOELECTRONICS, vol. 12, no. 7, 1997, pages 587 - 599, XP002113741 * |
WANG J ET AL: "DNA ELECTROCHEMICAL BIOSENSOR FOR THE DETECTION OF SHORT DNA SEQUENCES RELATED TO THE HUMAN IMMUNODEFICIENCY VIRUS", ANALYTICAL CHEMISTRY, vol. 68, no. 15, 1 August 1996 (1996-08-01), pages 2629 - 2634, XP000623884, ISSN: 0003-2700 * |
Also Published As
Publication number | Publication date |
---|---|
EP1055004A2 (en) | 2000-11-29 |
WO1999042827A2 (en) | 1999-08-26 |
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