WO1999012590A8 - Method and apparatus for collecting hyperconcentrated platelets - Google Patents

Method and apparatus for collecting hyperconcentrated platelets

Info

Publication number
WO1999012590A8
WO1999012590A8 PCT/US1998/018254 US9818254W WO9912590A8 WO 1999012590 A8 WO1999012590 A8 WO 1999012590A8 US 9818254 W US9818254 W US 9818254W WO 9912590 A8 WO9912590 A8 WO 9912590A8
Authority
WO
WIPO (PCT)
Prior art keywords
collecting
platelets
hyperconcentrated
fluid
fluid chamber
Prior art date
Application number
PCT/US1998/018254
Other languages
French (fr)
Other versions
WO1999012590A1 (en
Inventor
Larry Joe Dumont
Linda A Taylor
Geert Vanwaeg
Original Assignee
Cobe Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cobe Lab filed Critical Cobe Lab
Priority to CA002270202A priority Critical patent/CA2270202A1/en
Priority to JP51561799A priority patent/JP2002501422A/en
Priority to EP98944689A priority patent/EP0961622B1/en
Priority to DE69832472T priority patent/DE69832472T2/en
Publication of WO1999012590A1 publication Critical patent/WO1999012590A1/en
Publication of WO1999012590A8 publication Critical patent/WO1999012590A8/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3618—Magnetic separation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/362—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits changing physical properties of target cells by binding them to added particles to facilitate their subsequent separation from other cells, e.g. immunoaffinity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • A61M1/3633—Blood component filters, e.g. leukocyte filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0471—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with additional elutriation separation of different particles

Abstract

The instant invention relates to a method and the apparatus for collecting a hyperconcentrated platelet product. A fluid containing platelets and other particles flows into a fluid chamber at a flow rate. The flow rate of the fluid is selected to retain the majority of the platelets in the fluid chamber in a saturated bed. The platelets are collected from the fluid chamber without collecting the other particles to form a hyperconcentrated other particle reduced platelet product.
PCT/US1998/018254 1997-09-05 1998-09-02 Method and apparatus for collecting hyperconcentrated platelets WO1999012590A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002270202A CA2270202A1 (en) 1997-09-05 1998-09-02 Method and apparatus for collecting hyperconcentrated platelets
JP51561799A JP2002501422A (en) 1997-09-05 1998-09-02 Method and apparatus for collecting highly concentrated platelets
EP98944689A EP0961622B1 (en) 1997-09-05 1998-09-02 Method for collecting hyperconcentrated platelets
DE69832472T DE69832472T2 (en) 1997-09-05 1998-09-02 PROCESS FOR OBTAINING HYPER CONCENTRATED BLOOD PLATES

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/924,787 US6022306A (en) 1995-04-18 1997-09-05 Method and apparatus for collecting hyperconcentrated platelets
US08/924,787 1997-09-05

Publications (2)

Publication Number Publication Date
WO1999012590A1 WO1999012590A1 (en) 1999-03-18
WO1999012590A8 true WO1999012590A8 (en) 1999-09-02

Family

ID=25450729

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/018254 WO1999012590A1 (en) 1997-09-05 1998-09-02 Method and apparatus for collecting hyperconcentrated platelets

Country Status (6)

Country Link
US (1) US6022306A (en)
EP (1) EP0961622B1 (en)
JP (1) JP2002501422A (en)
CA (1) CA2270202A1 (en)
DE (1) DE69832472T2 (en)
WO (1) WO1999012590A1 (en)

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Also Published As

Publication number Publication date
JP2002501422A (en) 2002-01-15
WO1999012590A1 (en) 1999-03-18
DE69832472D1 (en) 2005-12-29
EP0961622A1 (en) 1999-12-08
DE69832472T2 (en) 2006-07-20
EP0961622B1 (en) 2005-11-23
CA2270202A1 (en) 1999-03-18
US6022306A (en) 2000-02-08

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