WO1999012529A3 - Transdermales therapeutisches system mit haftklebender reservoirschicht und unidirektional elastischer rückschicht - Google Patents

Transdermales therapeutisches system mit haftklebender reservoirschicht und unidirektional elastischer rückschicht Download PDF

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Publication number
WO1999012529A3
WO1999012529A3 PCT/EP1998/005321 EP9805321W WO9912529A3 WO 1999012529 A3 WO1999012529 A3 WO 1999012529A3 EP 9805321 W EP9805321 W EP 9805321W WO 9912529 A3 WO9912529 A3 WO 9912529A3
Authority
WO
WIPO (PCT)
Prior art keywords
therapeutic system
transdermal therapeutic
uni
reservoir
sensitive adhesive
Prior art date
Application number
PCT/EP1998/005321
Other languages
English (en)
French (fr)
Other versions
WO1999012529A2 (de
Inventor
Thomas Hille
Lothar Deurer
Original Assignee
Lohmann Therapie Syst Lts
Thomas Hille
Lothar Deurer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE59803647T priority Critical patent/DE59803647D1/de
Priority to CA002302601A priority patent/CA2302601C/en
Priority to DK98948853T priority patent/DK1009393T3/da
Priority to SI9830189T priority patent/SI1009393T1/xx
Priority to JP2000510427A priority patent/JP3847088B2/ja
Priority to US09/486,266 priority patent/US6814976B1/en
Priority to KR10-2000-7002344A priority patent/KR100515007B1/ko
Priority to AT98948853T priority patent/ATE215364T1/de
Application filed by Lohmann Therapie Syst Lts, Thomas Hille, Lothar Deurer filed Critical Lohmann Therapie Syst Lts
Priority to EP98948853A priority patent/EP1009393B1/de
Priority to AU95329/98A priority patent/AU738033B2/en
Publication of WO1999012529A2 publication Critical patent/WO1999012529A2/de
Publication of WO1999012529A3 publication Critical patent/WO1999012529A3/de
Priority to NO20001003A priority patent/NO327605B1/no
Priority to US10/891,942 priority patent/US7384651B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Abstract

Beschrieben wird ein transdermales therapeutisches System (TTS), insbesondere Pflaster, umfassend eine wiederablösbare Schutzschicht, eine haftklebende Reservoirschicht und eine gegebenenfalls haftkleberbeschichtete Rückschicht mit einem unidirektional, vorzugsweise längselatischen Material mit einer Elastizität von mindestens 20 %. Das TTS eignet sich insbesondere zur Anwendung als Mehrtagespflaster, etwa zur Behandlung von Schmerzen oder der Drogenabhängigkeit.
PCT/EP1998/005321 1997-09-05 1998-08-21 Transdermales therapeutisches system mit haftklebender reservoirschicht und unidirektional elastischer rückschicht WO1999012529A2 (de)

Priority Applications (12)

Application Number Priority Date Filing Date Title
KR10-2000-7002344A KR100515007B1 (ko) 1997-09-05 1998-08-21 감압성 접착제 저장층 및 단일방향성 탄성 백킹층을 갖춘경피 치료 시스템
DK98948853T DK1009393T3 (da) 1997-09-05 1998-08-21 Transdermalt, terapeutisk system med hæfteklæbende reservoirlag og bagsidelag, som er elastisk i én retning
SI9830189T SI1009393T1 (en) 1997-09-05 1998-08-21 Transdermal therapeutic system comprising a reservoir-type pressure-sensitive adhesive layer and a back layer with uni-directional resilience
JP2000510427A JP3847088B2 (ja) 1997-09-05 1998-08-21 貯蔵系感圧性接着層および一方向の弾性を有する裏当て層を含む経皮吸収治療システム
US09/486,266 US6814976B1 (en) 1997-09-05 1998-08-21 Transdermal therapeutic system comprising a reservoir-type pressure-sensitive adhesive layer and a back layer with uni-directional resilience
DE59803647T DE59803647D1 (de) 1997-09-05 1998-08-21 Transdermales therapeutisches system mit haftklebender reservoirschicht und unidirektional elastischer rückschicht
AT98948853T ATE215364T1 (de) 1997-09-05 1998-08-21 Transdermales therapeutisches system mit haftklebender reservoirschicht und unidirektional elastischer rückschicht
CA002302601A CA2302601C (en) 1997-09-05 1998-08-21 Transdermal therapeutic system comprising a reservoir-type pressure-sensitive adhesive layer and a back layer with uni-directional resilience
EP98948853A EP1009393B1 (de) 1997-09-05 1998-08-21 Transdermales therapeutisches system mit haftklebender reservoirschicht und unidirektional elastischer rückschicht
AU95329/98A AU738033B2 (en) 1997-09-05 1998-08-21 Transdermal therapeutic system with pressure-sensitive adhesive reservoir layer and unidirectionally elastic backing layer
NO20001003A NO327605B1 (no) 1997-09-05 2000-02-28 Transdermalt terapeutisk system, fremgangsmate for fremstilling samt andvendelse av dette
US10/891,942 US7384651B2 (en) 1997-09-05 2004-07-15 Transdermal therapeutic system comprising a reservoir type pressure sensitive adhesive layer and a back layer with uni-directional resilience

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19738855.8 1997-09-05
DE19738855A DE19738855C2 (de) 1997-09-05 1997-09-05 Transdermales therapeutisches System mit haftklebender Reservoirschicht und unidirektional elastischer Rückschicht

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US09/486,266 A-371-Of-International US6814976B1 (en) 1997-09-05 1998-08-21 Transdermal therapeutic system comprising a reservoir-type pressure-sensitive adhesive layer and a back layer with uni-directional resilience
US09486266 A-371-Of-International 1998-08-21
US10/891,942 Continuation US7384651B2 (en) 1997-09-05 2004-07-15 Transdermal therapeutic system comprising a reservoir type pressure sensitive adhesive layer and a back layer with uni-directional resilience

Publications (2)

Publication Number Publication Date
WO1999012529A2 WO1999012529A2 (de) 1999-03-18
WO1999012529A3 true WO1999012529A3 (de) 1999-05-27

Family

ID=7841309

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/005321 WO1999012529A2 (de) 1997-09-05 1998-08-21 Transdermales therapeutisches system mit haftklebender reservoirschicht und unidirektional elastischer rückschicht

Country Status (14)

Country Link
US (2) US6814976B1 (de)
EP (1) EP1009393B1 (de)
JP (1) JP3847088B2 (de)
KR (1) KR100515007B1 (de)
AT (1) ATE215364T1 (de)
AU (1) AU738033B2 (de)
CA (1) CA2302601C (de)
DE (2) DE19738855C2 (de)
DK (1) DK1009393T3 (de)
ES (1) ES2175792T3 (de)
NO (1) NO327605B1 (de)
PT (1) PT1009393E (de)
SI (1) SI1009393T1 (de)
WO (1) WO1999012529A2 (de)

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* Cited by examiner, † Cited by third party
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USRE41489E1 (en) 1997-02-24 2010-08-10 Purdue Pharma L.P. Method of providing sustained analgesia with buprenorphine

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DE10159745A1 (de) 2001-12-05 2003-07-03 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit verbessertem Langzeittragekomfort
ATE394097T1 (de) * 2002-03-20 2008-05-15 Euro Celtique Sa Verfahren zur verabreichung von buprenorphin zur behandlung von depression
EP1795189A3 (de) * 2002-03-20 2007-08-15 Euro-Celtique S.A. Verfahren zur Verabreichung von Buprenorphin zur Behandlung von Depression
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US8299079B2 (en) 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
DE102009056746A1 (de) * 2009-12-04 2011-06-09 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System für die Verabreichung von Peptiden
EP2366388A1 (de) * 2010-03-17 2011-09-21 Ratiopharm GmbH Nicht-okklusives transdermales therapeutisches System zur Verabreichung von Buprenorphin
WO2013006643A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
DE102014007650A1 (de) 2013-05-24 2014-11-27 Amw Gmbh Pflaster mit bielastischer Rückschicht
ES2599802T3 (es) * 2013-06-04 2017-02-03 Lts Lohmann Therapie-Systeme Ag Sistema de administración transdérmica
EP2921184A1 (de) * 2014-03-19 2015-09-23 LTS LOHMANN Therapie-Systeme AG Überpflaster mit verbesserter Verträglichkeit und einer langen Haftungsdauer und Verfahren zu seiner Herstellung
DE102014013448A1 (de) 2014-09-16 2016-03-17 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales Therapeutisches System umfassend Buprenorphin
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JP7420797B2 (ja) 2018-05-29 2024-01-23 モーニングサイド ベンチャー インベストメンツ リミテッド 薬剤送達の方法及びシステム
KR20220008824A (ko) 2019-04-17 2022-01-21 컴퍼스 패쓰파인더 리미티드 실로시빈으로 불안 장애, 두통 장애 및 섭식 장애를 치료하는 방법

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Also Published As

Publication number Publication date
EP1009393B1 (de) 2002-04-03
KR100515007B1 (ko) 2005-09-14
US7384651B2 (en) 2008-06-10
NO20001003L (no) 2000-02-28
DE19738855A1 (de) 1999-03-11
DE59803647D1 (de) 2002-05-08
EP1009393A2 (de) 2000-06-21
ATE215364T1 (de) 2002-04-15
AU9532998A (en) 1999-03-29
US20040253301A1 (en) 2004-12-16
US6814976B1 (en) 2004-11-09
WO1999012529A2 (de) 1999-03-18
DK1009393T3 (da) 2002-07-22
KR20010023691A (ko) 2001-03-26
JP2001515856A (ja) 2001-09-25
SI1009393T1 (en) 2002-10-31
ES2175792T3 (es) 2002-11-16
CA2302601A1 (en) 1999-03-18
JP3847088B2 (ja) 2006-11-15
CA2302601C (en) 2006-06-13
NO327605B1 (no) 2009-08-31
DE19738855C2 (de) 2001-01-04
NO20001003D0 (no) 2000-02-28
PT1009393E (pt) 2002-09-30
AU738033B2 (en) 2001-09-06

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