WO1998053311A3 - Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system - Google Patents

Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system Download PDF

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Publication number
WO1998053311A3
WO1998053311A3 PCT/US1998/010520 US9810520W WO9853311A3 WO 1998053311 A3 WO1998053311 A3 WO 1998053311A3 US 9810520 W US9810520 W US 9810520W WO 9853311 A3 WO9853311 A3 WO 9853311A3
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WO
WIPO (PCT)
Prior art keywords
methods
platform
microsystem
fluid movement
platforms
Prior art date
Application number
PCT/US1998/010520
Other languages
French (fr)
Other versions
WO1998053311A9 (en
WO1998053311A2 (en
Inventor
Gregory Kellogg
Stephen G Kieffer-Higgins
Bruce L Carvalho
Gene A Davis
John P Willis
Ted Minior
Laura L Chapman
Mikayla Kob
Sarah D Oeltjen
Shari Ommert
Alec Mian
Original Assignee
Gamera Bioscience Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gamera Bioscience Corp filed Critical Gamera Bioscience Corp
Priority to EP98923688A priority Critical patent/EP0983504A2/en
Priority to JP55068998A priority patent/JP3469585B2/en
Priority to AU75919/98A priority patent/AU7591998A/en
Publication of WO1998053311A2 publication Critical patent/WO1998053311A2/en
Publication of WO1998053311A3 publication Critical patent/WO1998053311A3/en
Publication of WO1998053311A9 publication Critical patent/WO1998053311A9/en

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    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/1624—Destructible or deformable element controlled
    • Y10T137/1797—Heat destructible or fusible
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/1624—Destructible or deformable element controlled
    • Y10T137/1797—Heat destructible or fusible
    • Y10T137/1812—In fluid flow path
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/4456—With liquid valves or liquid trap seals
    • Y10T137/4643—Liquid valves

Abstract

This invention provides methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. Specifically, the invention provides a microsystem platform for use with a micromanipulation device to manipulate the platform by rotation, thereby utilizing the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels embedded in the microplatform. The microsystem platforms of the invention are also provided having microfluidics components, resistive heating elements, temperature sensing elements, mixing structures, capillary and sacrificial valves, and methods for using these microsystems platforms for performing biological, enzymatic, immunological and chemical assays. An electronic spindle designed rotor capable of transferring electrical signals to and from the microsystem platforms of the invention is also provided.
PCT/US1998/010520 1997-05-23 1998-05-22 Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system WO1998053311A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP98923688A EP0983504A2 (en) 1997-05-23 1998-05-22 Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
JP55068998A JP3469585B2 (en) 1997-05-23 1998-05-22 Apparatus and method for using centripetal acceleration to drive flow motion in microfluidics systems
AU75919/98A AU7591998A (en) 1997-05-23 1998-05-22 Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4748897P 1997-05-23 1997-05-23
US60/047,488 1997-05-23

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WO1998053311A3 true WO1998053311A3 (en) 1999-02-18
WO1998053311A9 WO1998053311A9 (en) 1999-04-22

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JP (4) JP3469585B2 (en)
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