WO1998048052A3 - Amplification based mutation detection - Google Patents

Amplification based mutation detection Download PDF

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Publication number
WO1998048052A3
WO1998048052A3 PCT/US1998/007909 US9807909W WO9848052A3 WO 1998048052 A3 WO1998048052 A3 WO 1998048052A3 US 9807909 W US9807909 W US 9807909W WO 9848052 A3 WO9848052 A3 WO 9848052A3
Authority
WO
WIPO (PCT)
Prior art keywords
amplification based
mutation detection
based mutation
amplification
detection
Prior art date
Application number
PCT/US1998/007909
Other languages
French (fr)
Other versions
WO1998048052A2 (en
Inventor
Cynthia Jou
Ronald L Marshall
Christi P Scheffel
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Priority to CA002287506A priority Critical patent/CA2287506A1/en
Priority to EP98915634A priority patent/EP0975804A2/en
Priority to JP54623098A priority patent/JP2001522243A/en
Publication of WO1998048052A2 publication Critical patent/WO1998048052A2/en
Publication of WO1998048052A3 publication Critical patent/WO1998048052A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

Abstract

Provided herein is an amplification based method for detecting mutant nucleic acid sequences.
PCT/US1998/007909 1997-04-18 1998-04-17 Amplification based mutation detection WO1998048052A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002287506A CA2287506A1 (en) 1997-04-18 1998-04-17 Amplification based mutation detection
EP98915634A EP0975804A2 (en) 1997-04-18 1998-04-17 Amplification based mutation detection
JP54623098A JP2001522243A (en) 1997-04-18 1998-04-17 Amplification-based mutation detection

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84427597A 1997-04-18 1997-04-18
US08/844,275 1997-04-18

Publications (2)

Publication Number Publication Date
WO1998048052A2 WO1998048052A2 (en) 1998-10-29
WO1998048052A3 true WO1998048052A3 (en) 1999-01-21

Family

ID=25292274

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/007909 WO1998048052A2 (en) 1997-04-18 1998-04-17 Amplification based mutation detection

Country Status (4)

Country Link
EP (1) EP0975804A2 (en)
JP (1) JP2001522243A (en)
CA (1) CA2287506A1 (en)
WO (1) WO1998048052A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7250252B2 (en) 1999-12-30 2007-07-31 David Aaron Katz Amplification based polymorphism detection
EP1330549A2 (en) * 2000-10-27 2003-07-30 Abbott Laboratories Genotyping using partially-complementary probes

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991012343A2 (en) * 1990-02-07 1991-08-22 F. Hoffmann-La Roche Ag Detection of point mutations in genes encoding gtp binding proteins
EP0459533A2 (en) * 1986-03-13 1991-12-04 F. Hoffmann-La Roche Ag Probe groups for the detection of nucleotide variations and genetic polymorphisms
WO1994009156A1 (en) * 1992-10-08 1994-04-28 The Regents Of The University Of California Pcr assays to determine the presence and concentration of a target
US5527676A (en) * 1989-03-29 1996-06-18 The Johns Hopkins University Detection of loss of the wild-type P53 gene and kits therefor
US5582989A (en) * 1988-10-12 1996-12-10 Baylor College Of Medicine Multiplex genomic DNA amplification for deletion detection
WO1997007235A2 (en) * 1995-08-14 1997-02-27 Abbott Laboratories All-in-one nucleic acid amplification assay

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0459533A2 (en) * 1986-03-13 1991-12-04 F. Hoffmann-La Roche Ag Probe groups for the detection of nucleotide variations and genetic polymorphisms
US5582989A (en) * 1988-10-12 1996-12-10 Baylor College Of Medicine Multiplex genomic DNA amplification for deletion detection
US5527676A (en) * 1989-03-29 1996-06-18 The Johns Hopkins University Detection of loss of the wild-type P53 gene and kits therefor
WO1991012343A2 (en) * 1990-02-07 1991-08-22 F. Hoffmann-La Roche Ag Detection of point mutations in genes encoding gtp binding proteins
WO1994009156A1 (en) * 1992-10-08 1994-04-28 The Regents Of The University Of California Pcr assays to determine the presence and concentration of a target
WO1997007235A2 (en) * 1995-08-14 1997-02-27 Abbott Laboratories All-in-one nucleic acid amplification assay

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HUNAULT M ET AL.: "Automated detection of the factor V leiden mutation using microparticle enzyme immunoassay (MEIA).", BLOOD, vol. 90, no. 10 Suppl. 1, 1997, pages 150a, XP002083117 *
LEMOINE N R ET AL.: "Absence of activatng transmembrane mutations in the c-erbB-2 proto-oncogene in human breast cancer", ONCOGENE, vol. 5, 1990, pages 237 - 239, XP002083306 *
SAIKI R K ET AL.: "Analysis of enzymatically amplified beta-globin and HLA-DQalpha DNA with allele-specific oligonucleotides.", NATURE, vol. 324, no. 13, 1986, pages 163 - 166, XP002083116 *
WATANABE M ET AL.: "International comparison on ras gene mutations in latent prostate carcinoma", INTERNATIONAL JOURNAL OF CANCER, vol. 58, 1994, pages 174 - 178, XP002083305 *

Also Published As

Publication number Publication date
EP0975804A2 (en) 2000-02-02
CA2287506A1 (en) 1998-10-29
WO1998048052A2 (en) 1998-10-29
JP2001522243A (en) 2001-11-13

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