WO1998029433A3 - Method for solubilization and naturation of somatotropins - Google Patents
Method for solubilization and naturation of somatotropins Download PDFInfo
- Publication number
- WO1998029433A3 WO1998029433A3 PCT/US1997/024287 US9724287W WO9829433A3 WO 1998029433 A3 WO1998029433 A3 WO 1998029433A3 US 9724287 W US9724287 W US 9724287W WO 9829433 A3 WO9829433 A3 WO 9829433A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- somatotropin
- naturation
- solubilization
- detergent composition
- somatotropins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormones [GH] (Somatotropin)
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53035698A JP2001509793A (en) | 1996-12-31 | 1997-12-31 | Somatotropin solubilization and regeneration method |
KR10-1999-7005951A KR100487299B1 (en) | 1996-12-31 | 1997-12-31 | Method for solubilization and naturation of somatotropins |
CA002276252A CA2276252A1 (en) | 1996-12-31 | 1997-12-31 | Method for solubilization and naturation of somatotropins |
EP97955015A EP0948540A2 (en) | 1996-12-31 | 1997-12-31 | Method for solubilization and naturation of somatotropins |
AU69370/98A AU6937098A (en) | 1996-12-31 | 1997-12-31 | Method for solubilization and naturation of somatotropins |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3480896P | 1996-12-31 | 1996-12-31 | |
US60/034,808 | 1996-12-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998029433A2 WO1998029433A2 (en) | 1998-07-09 |
WO1998029433A3 true WO1998029433A3 (en) | 1998-10-15 |
Family
ID=21878743
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/024287 WO1998029433A2 (en) | 1996-12-31 | 1997-12-31 | Method for solubilization and naturation of somatotropins |
Country Status (8)
Country | Link |
---|---|
US (3) | US6034224A (en) |
EP (1) | EP0948540A2 (en) |
JP (1) | JP2001509793A (en) |
KR (1) | KR100487299B1 (en) |
AU (1) | AU6937098A (en) |
CA (1) | CA2276252A1 (en) |
WO (1) | WO1998029433A2 (en) |
ZA (1) | ZA9711733B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA9711733B (en) * | 1996-12-31 | 1998-07-01 | Monsanto Co | Method for solubilization and naturation of somatotropins |
US6743600B1 (en) | 1999-04-30 | 2004-06-01 | Monsanto Technologies Llc | Method of removing N-terminal alanine residues from polypeptides with Aeromonas aminopeptidase |
US6794159B1 (en) | 1999-04-30 | 2004-09-21 | Pharmacia Corporation | Method of removing n-terminal alanine residues from polypeptides with aeromonas aminopeptidase |
WO2009136568A1 (en) * | 2008-05-08 | 2009-11-12 | 味の素株式会社 | Protein reforming method |
BR102013026129A2 (en) * | 2013-10-10 | 2016-05-24 | Ouro Fino Participações E Empreendimentos S A | process for the production of active recombinant bovine somatotropin and product obtained |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0218374A1 (en) * | 1985-09-06 | 1987-04-15 | International Minerals And Chemical Corporation | Purification and activation of proteins from insoluble inclusion bodies |
EP0226448A2 (en) * | 1985-12-11 | 1987-06-24 | Fidelity Food Technologies Pty. Ltd. | Solubilisation of protein aggregates |
EP0295859A2 (en) * | 1987-06-15 | 1988-12-21 | Southern Cross Biotech Pty.Ltd. | Production of proteins in active forms |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3985722A (en) * | 1973-12-12 | 1976-10-12 | Ajinomoto Co., Inc. | Process for preparing N-higher aliphatic acyl derivatives of amino acids, peptides or proteins |
US4443539A (en) * | 1980-02-05 | 1984-04-17 | The Upjohn Company | Process for preparing bovine growth hormone |
CA1224432A (en) * | 1982-08-17 | 1987-07-21 | Gary N. Buell | Dna sequences, recombinant dna molecules and processes for producing bovine growth hormone-like polypeptides in high yield |
US4511503A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
US4518526A (en) * | 1982-12-22 | 1985-05-21 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
US4652630A (en) * | 1985-02-22 | 1987-03-24 | Monsanto Company | Method of somatotropin naturation |
ES8800957A1 (en) * | 1985-02-22 | 1987-12-01 | Monsanto Co | Method of somatotropin solubilization and naturation. |
GB8508340D0 (en) * | 1985-03-29 | 1985-05-09 | Creighton T E | Production of protein |
ATE76435T1 (en) * | 1985-06-26 | 1992-06-15 | Upjohn Co | SOLUBILIZATION AND OXIDATION OF SOMATOTROPIN FROM TRANSFORMED MICROORGANISMS. |
US4766224A (en) * | 1985-08-19 | 1988-08-23 | International Minerals & Chemical Corp. | Purification and activation of proteins from insoluble inclusion bodies |
US4766205A (en) * | 1985-11-13 | 1988-08-23 | Beatrice Companies, Inc. | Method for isolation of recombinant polypeptides in biologically active forms |
US4888416A (en) * | 1987-03-30 | 1989-12-19 | International Minerals & Chemical Corp. | Method for stabilizing somatotropins |
US4985544A (en) * | 1987-08-04 | 1991-01-15 | Kyowa Hakko Kogyo Co., Ltd. | Process for renaturing fish growth hormone |
JPH01132598A (en) * | 1987-10-14 | 1989-05-25 | Pitman Moore Inc | Method for promoting production of intramolecular disulfide bond in recominant protein contained in modifier solution |
US4975529A (en) * | 1989-08-18 | 1990-12-04 | Monsanto Company | Method of folding somatotropins |
US5182369A (en) * | 1990-02-28 | 1993-01-26 | Monsanto Company | Method for purifying somatotropin monomers |
US5109117A (en) * | 1990-06-26 | 1992-04-28 | Monsanto Company | Method of somatotropin naturation using urea and a soluble organic alcohol |
US5023323A (en) * | 1990-09-12 | 1991-06-11 | Monsanto Company | Method of somatotropin naturation |
US5240834A (en) * | 1991-01-22 | 1993-08-31 | Albert Einstein College Of Medicine Of Yeshiva University | Solubilization of protein after bacterial expression using sarkosyl |
SE9201073D0 (en) * | 1992-04-03 | 1992-04-03 | Kabi Pharmacia Ab | PROTEIN FORMULATION |
WO1995012385A1 (en) * | 1993-11-03 | 1995-05-11 | Isotech Medical, Inc. | Microparticular pharmaceutical compositions in micellar form |
JPH09510182A (en) * | 1993-11-17 | 1997-10-14 | エルディーエス・テクノロジーズ・インコーポレーテッド | Encapsulated transparent liquid for drug delivery |
ZA9711733B (en) * | 1996-12-31 | 1998-07-01 | Monsanto Co | Method for solubilization and naturation of somatotropins |
-
1997
- 1997-12-30 ZA ZA9711733A patent/ZA9711733B/en unknown
- 1997-12-31 EP EP97955015A patent/EP0948540A2/en not_active Withdrawn
- 1997-12-31 AU AU69370/98A patent/AU6937098A/en not_active Abandoned
- 1997-12-31 WO PCT/US1997/024287 patent/WO1998029433A2/en active IP Right Grant
- 1997-12-31 KR KR10-1999-7005951A patent/KR100487299B1/en not_active IP Right Cessation
- 1997-12-31 JP JP53035698A patent/JP2001509793A/en active Pending
- 1997-12-31 US US09/002,565 patent/US6034224A/en not_active Expired - Lifetime
- 1997-12-31 CA CA002276252A patent/CA2276252A1/en not_active Abandoned
-
1999
- 1999-12-15 US US09/461,784 patent/US6410694B1/en not_active Expired - Lifetime
-
2001
- 2001-11-02 US US10/002,084 patent/US6562951B2/en not_active Expired - Lifetime
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0218374A1 (en) * | 1985-09-06 | 1987-04-15 | International Minerals And Chemical Corporation | Purification and activation of proteins from insoluble inclusion bodies |
EP0226448A2 (en) * | 1985-12-11 | 1987-06-24 | Fidelity Food Technologies Pty. Ltd. | Solubilisation of protein aggregates |
EP0295859A2 (en) * | 1987-06-15 | 1988-12-21 | Southern Cross Biotech Pty.Ltd. | Production of proteins in active forms |
Also Published As
Publication number | Publication date |
---|---|
KR100487299B1 (en) | 2005-05-03 |
US6410694B1 (en) | 2002-06-25 |
US20020058792A1 (en) | 2002-05-16 |
WO1998029433A2 (en) | 1998-07-09 |
EP0948540A2 (en) | 1999-10-13 |
AU6937098A (en) | 1998-07-31 |
US6562951B2 (en) | 2003-05-13 |
JP2001509793A (en) | 2001-07-24 |
CA2276252A1 (en) | 1998-07-09 |
ZA9711733B (en) | 1998-07-01 |
KR20000069805A (en) | 2000-11-25 |
US6034224A (en) | 2000-03-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE210719T1 (en) | COMPOSITIONS FOR A SOAP BAR WITH ALPHA-SULFOFATTY ACID ESTERS AND LONG CHAIN FATTY ACIDS | |
PH30296A (en) | Process to improve alkyl ester sulfonate surfactant compositions | |
IS3527A7 (en) | Method of creating images to be used to decorate an object to be shaped | |
IE902076L (en) | High active detergent particles which are dispersible in¹cold water | |
WO1998029433A3 (en) | Method for solubilization and naturation of somatotropins | |
ZA943983B (en) | Lipopeptides from actinoplanes sp. with pharmacological action process for their preparation and the use thereof | |
NO884001L (en) | THICKNESSED Aqueous surfactants, SPECIFICALLY USED FOR COSMETIC PREPARATIONS. | |
ES2076825T3 (en) | IMPROVED CHOCOLATE COMPOSITIONS BASED ON HARD FAT ADDITIVES. | |
DK1003824T3 (en) | Method for reducing the content of unsaturated fatty acids in fatty acid compositions | |
GR850409B (en) | ||
GR850408B (en) | ||
MY118989A (en) | Process for the preparation of derivatives of fatty acids | |
ES2062282T3 (en) | OPTICALLY ACTIVE CARBOXYL ACID ESTER RACEMIZATION PROCESS. | |
MY104501A (en) | An alkyl benzine sulfonate laundry bar. | |
DE69934304D1 (en) | IMPROVED PROCESS FOR SYNTHESIS AND CLEANING OF UNFORGETTABLE FATS | |
ES2163038T3 (en) | PROCEDURE FOR THE PREPARATION OF POTASSIUM CLAVULANATE. | |
BR9505529A (en) | Enzymatic process for the preparation of polyunsaturated fatty acids and fatty acid mixtures obtained | |
JPS5327603A (en) | Detergent composition | |
ES8608304A1 (en) | Method of attaching parts of a separable bottom end assembly to a continuous slide fastener chain. | |
BR0016204A (en) | Composition | |
MY106341A (en) | A surfactant mixture based on (alpha)-sulfofatty acid methyl ester salts, a process for its production and its use | |
PT886652E (en) | PROCESS OF SOLUBILIZATION OF PULMONARY TENSIOACTIVE PEPTIDES | |
JPS52147603A (en) | Detergent paste for washing hands and legs stained with grease etc. | |
EP0902006A3 (en) | Oxidation stable oleins | |
GB2174089B (en) | Process for producing unsaturated fatty acid lower alkyl ester sulfonate |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW AM AZ BY KG KZ MD RU TJ TM |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW SD SZ UG ZW AT BE CH DE DK ES FI FR GB GR IE IT |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
AK | Designated states |
Kind code of ref document: A3 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW AM AZ BY KG KZ MD RU TJ TM |
|
AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): GH GM KE LS MW SD SZ UG ZW AT BE CH DE DK ES FI FR GB GR IE IT |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
ENP | Entry into the national phase |
Ref document number: 2276252 Country of ref document: CA Ref country code: CA Ref document number: 2276252 Kind code of ref document: A Format of ref document f/p: F |
|
ENP | Entry into the national phase |
Ref country code: JP Ref document number: 1998 530356 Kind code of ref document: A Format of ref document f/p: F |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1019997005951 Country of ref document: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: PA/a/1999/006232 Country of ref document: MX |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1997955015 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 1997955015 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWP | Wipo information: published in national office |
Ref document number: 1019997005951 Country of ref document: KR |
|
WWG | Wipo information: grant in national office |
Ref document number: 1019997005951 Country of ref document: KR |