WO1998022097A3 - Controlled release matrix composition using polar polymer or monomer and poly(acrylic acid) blend - Google Patents

Controlled release matrix composition using polar polymer or monomer and poly(acrylic acid) blend Download PDF

Info

Publication number
WO1998022097A3
WO1998022097A3 PCT/US1997/021280 US9721280W WO9822097A3 WO 1998022097 A3 WO1998022097 A3 WO 1998022097A3 US 9721280 W US9721280 W US 9721280W WO 9822097 A3 WO9822097 A3 WO 9822097A3
Authority
WO
WIPO (PCT)
Prior art keywords
monomer
poly
polar polymer
acrylic acid
blend
Prior art date
Application number
PCT/US1997/021280
Other languages
French (fr)
Other versions
WO1998022097A2 (en
Inventor
Jane Pei-Fan Bai
Original Assignee
Bio Advances Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Advances Llc filed Critical Bio Advances Llc
Priority to AU72981/98A priority Critical patent/AU7298198A/en
Publication of WO1998022097A2 publication Critical patent/WO1998022097A2/en
Publication of WO1998022097A3 publication Critical patent/WO1998022097A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Abstract

A controlled release matrix system comprising a blend of poly(acrylic acid) and a polar polymer or monomer, said polar polymer or monomer having a carbon-oxygen ratio equal to or less than 1.9:1 and a carbon-hydroxyl group ratio of 5:1, the weight ratio of said poly(acrylic acid) to said polar polymer or monomer ranging from 10:90 to 90:10, is useful for the delivery of pharmaceutical agents.
PCT/US1997/021280 1996-11-20 1997-11-20 Controlled release matrix composition using polar polymer or monomer and poly(acrylic acid) blend WO1998022097A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU72981/98A AU7298198A (en) 1996-11-20 1997-11-20 Controlled release matrix composition using polar polymer or monomer and poly (acrylic acid) blend

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US3133496P 1996-11-20 1996-11-20
US60/031,334 1996-11-20
US97292997A 1997-11-18 1997-11-18
US08/972,929 1997-11-18

Publications (2)

Publication Number Publication Date
WO1998022097A2 WO1998022097A2 (en) 1998-05-28
WO1998022097A3 true WO1998022097A3 (en) 1998-10-08

Family

ID=26707094

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/021280 WO1998022097A2 (en) 1996-11-20 1997-11-20 Controlled release matrix composition using polar polymer or monomer and poly(acrylic acid) blend

Country Status (1)

Country Link
WO (1) WO1998022097A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9445936B2 (en) 2011-02-04 2016-09-20 Joseph E. Kovarik Method of treating snoring and obstructive sleep apnea
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284235B1 (en) * 2000-02-11 2001-09-04 National Starch And Chemical Company Investment Holding Corporation Bioadhesive composition
US6955821B2 (en) 2000-04-28 2005-10-18 Adams Laboratories, Inc. Sustained release formulations of guaifenesin and additional drug ingredients
US6372252B1 (en) * 2000-04-28 2002-04-16 Adams Laboratories, Inc. Guaifenesin sustained release formulation and tablets
GB0116860D0 (en) * 2001-07-10 2001-09-05 Univ Montfort Gel compositions
US7846478B2 (en) 2002-01-31 2010-12-07 Henkel Ag & Co. Kgaa Bioadhesive composition
DE10358748A1 (en) * 2003-12-12 2005-07-14 Lts Lohmann Therapie-Systeme Ag Dosage form based on crosslinked hydrophilic polymers
DE102004011686A1 (en) * 2004-03-10 2005-09-29 Novosis Ag Dermal or transdermal therapeutic system with matrix component of renewable tubing
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11357722B2 (en) 2011-02-04 2022-06-14 Seed Health, Inc. Method and system for preventing sore throat in humans
US20130202675A1 (en) 2012-02-03 2013-08-08 Dynasil Biomedical Corporation Systems and methods for the fabrication of tissue patches
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
EP3129012A4 (en) * 2014-04-08 2017-10-11 Teikoku Pharma USA, Inc. Rivastigmine transdermal compositions and methods of using the same
US10588998B2 (en) 2015-08-07 2020-03-17 Xcede Technologies, Inc. Adhesive compositions and related methods
US9833538B2 (en) 2015-08-07 2017-12-05 Xcede Technologies, Inc. Adhesive compositions and related methods
EP3364955B1 (en) 2015-10-09 2022-04-20 RB Health (US) LLC Pharmaceutical formulation

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2497098A1 (en) * 1980-12-29 1982-07-02 Teijin Ltd POLYMERIC COMPOSITION FOR PROTECTING AN LESEEE OF THE ORAL MUCOUS MEMBRANE
EP0159604A2 (en) * 1984-04-09 1985-10-30 Toyo Boseki Kabushiki Kaisha Sustained-release preparation applicable to mucous membrane in oral cavity
FR2582942A1 (en) * 1985-06-05 1986-12-12 Yamanouchi Trading Co Ltd ADHESIVE MEDICAL TAPE FOR ORAL MUCOSA
US4876092A (en) * 1986-02-01 1989-10-24 Teikoku Seiyaku Kabushiki Kaisha Sheet-shaped adhesive preparation applicable to oral cavity
EP0598606A1 (en) * 1992-11-18 1994-05-25 JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. Extrudable compositions for topical or transdermal drug delivery

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2497098A1 (en) * 1980-12-29 1982-07-02 Teijin Ltd POLYMERIC COMPOSITION FOR PROTECTING AN LESEEE OF THE ORAL MUCOUS MEMBRANE
EP0159604A2 (en) * 1984-04-09 1985-10-30 Toyo Boseki Kabushiki Kaisha Sustained-release preparation applicable to mucous membrane in oral cavity
FR2582942A1 (en) * 1985-06-05 1986-12-12 Yamanouchi Trading Co Ltd ADHESIVE MEDICAL TAPE FOR ORAL MUCOSA
US4876092A (en) * 1986-02-01 1989-10-24 Teikoku Seiyaku Kabushiki Kaisha Sheet-shaped adhesive preparation applicable to oral cavity
EP0598606A1 (en) * 1992-11-18 1994-05-25 JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. Extrudable compositions for topical or transdermal drug delivery

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9445936B2 (en) 2011-02-04 2016-09-20 Joseph E. Kovarik Method of treating snoring and obstructive sleep apnea
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis

Also Published As

Publication number Publication date
WO1998022097A2 (en) 1998-05-28

Similar Documents

Publication Publication Date Title
WO1998022097A3 (en) Controlled release matrix composition using polar polymer or monomer and poly(acrylic acid) blend
CA2219698A1 (en) Sustained-release preparation
CA2019410A1 (en) Liquid polymer composition, and method of use
ES2173370T3 (en) ADHESIVE AND BINDING AGENT FOR AN ADHESIVE AND BINDING THERAPEUTIC SYSTEM.
CA2214100A1 (en) Sustained release formulation containing three different types of polymers
ATE253900T1 (en) AQUEOUS DISPERSION SUITABLE FOR PRODUCING COATING AND BINDING AGENTS FOR SOLID ORAL MEDICINAL FORMS
AU5795494A (en) Biocompatible monomer and polymer compositions
EP2258407A3 (en) Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
CA2320259A1 (en) Bioactive agent release coating
GR3036586T3 (en) Novel hydrogels containing triblock copolymers, and preparation and use thereof
CA2328703A1 (en) Delavirdine tablet formulation
CA2223588A1 (en) Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
CA2150119A1 (en) Tastemasked pharmaceutical materials
CA2222567A1 (en) High viscosity liquid controlled biologically active delivery system
NZ336462A (en) Pharmaceutical composition of fenofibrate with high biological availability
NZ506415A (en) Liquid polymeric compositions for controlled release of bioactive substances using a polymer to active agent ratio of less than 1:1
WO1993025191A3 (en) Bioresorbable polymer microspheres free from surface active agents, their preparation and application as drug
CA2157323A1 (en) Gepirone dosage form
ES2166025T3 (en) BINDING AGENTS FOR POOR COATING MASSES IN ISSUANCE.
EP1842544A3 (en) Alginate compositions
CA2085871A1 (en) A controlled release drug dispersion delivery device
PL340245A1 (en) Coating composition of high solid matter content
EP0823458A4 (en) Polymeric material, medical material and liquid polymer composition
CA2209322A1 (en) Coextrusion binder, its use for a multilayer structure and the structure thus obtained
CA2254848A1 (en) Methods for sterilizing male mammals

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AU BA BB BG BR CA CN CU CZ EE GE HU ID IL IS JP KP KR LC LK LR LT LV MD MG MK MN MX NO NZ PL RO SG SI SK SL TR TT UA UZ VN YU AM AZ BY KG KZ MD RU TJ TM

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH KE LS MW SD SZ UG ZW AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AL AU BA BB BG BR CA CN CU CZ EE GE HU ID IL IS JP KP KR LC LK LR LT LV MD MG MK MN MX NO NZ PL RO SG SI SK SL TR TT UA UZ VN YU AM AZ BY KG KZ MD RU TJ TM

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH KE LS MW SD SZ UG ZW AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA