WO1998008469A3 - Method, instruments and kit for autologous transplantation - Google Patents

Method, instruments and kit for autologous transplantation Download PDF

Info

Publication number
WO1998008469A3
WO1998008469A3 PCT/US1997/015258 US9715258W WO9808469A3 WO 1998008469 A3 WO1998008469 A3 WO 1998008469A3 US 9715258 W US9715258 W US 9715258W WO 9808469 A3 WO9808469 A3 WO 9808469A3
Authority
WO
WIPO (PCT)
Prior art keywords
kit
instruments
autologous transplantation
transplantation
chondrocytes
Prior art date
Application number
PCT/US1997/015258
Other languages
French (fr)
Other versions
WO1998008469A2 (en
Inventor
Henrik Vibe-Hansen
Charlotte Lundsgaard
Ahmed Idouraine
Kurt B Osther
Original Assignee
Vts Holdings Ltd
Vibe Hansen Henrik
Charlotte Lundsgaard
Ahmed Idouraine
Kurt B Osther
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27107401&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO1998008469(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/704,891 external-priority patent/US5759190A/en
Priority to BR9711967-9A priority Critical patent/BR9711967A/en
Priority to SI9730655T priority patent/SI1006950T1/en
Priority to SK240-99A priority patent/SK285075B6/en
Priority to HU0400358A priority patent/HU225952B1/en
Priority to JP51196798A priority patent/JP2002502272A/en
Priority to AT97939677T priority patent/ATE263524T1/en
Priority to EP97939677A priority patent/EP1006950B1/en
Priority to MXPA99001794A priority patent/MXPA99001794A/en
Application filed by Vts Holdings Ltd, Vibe Hansen Henrik, Charlotte Lundsgaard, Ahmed Idouraine, Kurt B Osther filed Critical Vts Holdings Ltd
Priority to NZ334400A priority patent/NZ334400A/en
Priority to CA002264138A priority patent/CA2264138C/en
Priority to AU41710/97A priority patent/AU731162B2/en
Priority to DK03023272T priority patent/DK1384452T3/en
Priority to IL128580A priority patent/IL128580A/en
Priority to DE69728569T priority patent/DE69728569T2/en
Publication of WO1998008469A2 publication Critical patent/WO1998008469A2/en
Publication of WO1998008469A3 publication Critical patent/WO1998008469A3/en
Priority to NO990933A priority patent/NO990933L/en
Priority to HK00104418A priority patent/HK1025035A1/en
Priority to AU53994/01A priority patent/AU775219B2/en
Priority to AU29302/02A priority patent/AU778308B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2/2846Support means for bone substitute or for bone graft implants, e.g. membranes or plates for covering bone defects
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30756Cartilage endoprostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491Surgical glue applicators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/38Joints for elbows or knees
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2835Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/30004Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
    • A61F2002/30016Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in hardness, e.g. Vickers, Shore, Brinell
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30062(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30756Cartilage endoprostheses
    • A61F2002/30761Support means for artificial cartilage, e.g. cartilage defect covering membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30756Cartilage endoprostheses
    • A61F2002/30762Means for culturing cartilage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0019Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in hardness, e.g. Vickers, Shore, Brinell
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00365Proteins; Polypeptides; Degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/06Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus

Abstract

Method for the effective transplantation of chondrocytes/cartilage to an articular joint surface defect is taught, as well as a description of certain instruments and kit for practicing the invention.
PCT/US1997/015258 1996-08-30 1997-08-29 Method, instruments and kit for autologous transplantation WO1998008469A2 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
IL128580A IL128580A (en) 1996-08-30 1997-08-29 Methods for treating an articulating joint surface of a joint surface cartilage of a non-human mammal and kits for chondrocyte transplantation
DE69728569T DE69728569T2 (en) 1996-08-30 1997-08-29 Kit for chondrocyte transplantation in a joint
AU41710/97A AU731162B2 (en) 1996-08-30 1997-08-29 Method, instruments and kit for autologous transplantation
SK240-99A SK285075B6 (en) 1996-08-30 1997-08-29 Kit for chondrocytes transplantation in a joint
HU0400358A HU225952B1 (en) 1996-08-30 1997-08-29 Plaster for treating of joint surface cartilage
JP51196798A JP2002502272A (en) 1996-08-30 1997-08-29 Methods, devices and kits for autografting
AT97939677T ATE263524T1 (en) 1996-08-30 1997-08-29 NIT FOR CHONDROCYTE TRANSPLANTATION IN A JOINT
EP97939677A EP1006950B1 (en) 1996-08-30 1997-08-29 Kit for chondrocytes transplantation in a joint
MXPA99001794A MXPA99001794A (en) 1996-08-30 1997-08-29 Method, instruments and kit for autologous transplantation.
BR9711967-9A BR9711967A (en) 1996-08-30 1997-08-29 Processes for the effective treatment of articulating joint surface cartilage and for the transplantation of chondrocytes in a suitable matrix, kit for chondrocyte transplantation and for the practice of processes, and, surgical instrument.
NZ334400A NZ334400A (en) 1996-08-30 1997-08-29 Method, instruments and kit for autologous transplantation comprising hemostatic barrier and a covering patch
CA002264138A CA2264138C (en) 1996-08-30 1997-08-29 Method, instruments and kit for autologous transplantation
SI9730655T SI1006950T1 (en) 1996-08-30 1997-08-29 Kit for chondrocytes transplantation in a joint
DK03023272T DK1384452T3 (en) 1996-08-30 1997-08-29 Method of Preparing a Kit for Autologous Transplantation
NO990933A NO990933L (en) 1996-08-30 1999-02-26 Procedure, instruments and equipment for autologous transplantation
HK00104418A HK1025035A1 (en) 1996-08-30 2000-07-19 A cartilage repair structure for repair of a defect in articular cartilage.
AU53994/01A AU775219B2 (en) 1996-08-30 2001-06-21 Method, instruments and kit for autologous transplantation
AU29302/02A AU778308B2 (en) 1996-08-30 2002-03-28 Method, instruments and kit for autologous transplantation

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/704,891 US5759190A (en) 1996-08-30 1996-08-30 Method and kit for autologous transplantation
US08/704,891 1996-08-30
US08/857,090 1997-05-15
US08/857,090 US5989269A (en) 1996-08-30 1997-05-15 Method, instruments and kit for autologous transplantation

Publications (2)

Publication Number Publication Date
WO1998008469A2 WO1998008469A2 (en) 1998-03-05
WO1998008469A3 true WO1998008469A3 (en) 1998-04-23

Family

ID=27107401

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/015258 WO1998008469A2 (en) 1996-08-30 1997-08-29 Method, instruments and kit for autologous transplantation

Country Status (27)

Country Link
US (9) US5989269A (en)
EP (4) EP1181908B1 (en)
JP (3) JP2002502272A (en)
KR (2) KR20030097603A (en)
CN (2) CN1200656C (en)
AT (3) ATE428376T1 (en)
AU (1) AU731162B2 (en)
BR (1) BR9711967A (en)
CA (2) CA2264138C (en)
CZ (1) CZ297248B6 (en)
DE (4) DE69726896T2 (en)
DK (5) DK1384452T3 (en)
ES (3) ES2325206T3 (en)
HK (2) HK1025035A1 (en)
HU (2) HUP0002980A3 (en)
IL (1) IL128580A (en)
MX (1) MXPA99001794A (en)
NO (1) NO990933L (en)
NZ (3) NZ518474A (en)
PL (1) PL331834A1 (en)
PT (3) PT1006950E (en)
RU (2) RU2214197C2 (en)
SG (2) SG120854A1 (en)
SI (2) SI1006950T1 (en)
SK (1) SK285075B6 (en)
TR (3) TR199900437T2 (en)
WO (1) WO1998008469A2 (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE43282E1 (en) 1998-09-14 2012-03-27 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and devising treatment
US8690945B2 (en) 2001-05-25 2014-04-08 Conformis, Inc. Patient selectable knee arthroplasty devices
US8862202B2 (en) 1998-09-14 2014-10-14 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and preventing damage
US8882847B2 (en) 2001-05-25 2014-11-11 Conformis, Inc. Patient selectable knee joint arthroplasty devices
US8906107B2 (en) 2001-05-25 2014-12-09 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US8932363B2 (en) 2002-11-07 2015-01-13 Conformis, Inc. Methods for determining meniscal size and shape and for devising treatment
US9020788B2 (en) 1997-01-08 2015-04-28 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US9180015B2 (en) 2008-03-05 2015-11-10 Conformis, Inc. Implants for altering wear patterns of articular surfaces
US9286686B2 (en) 1998-09-14 2016-03-15 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and assessing cartilage loss
US9308091B2 (en) 2001-05-25 2016-04-12 Conformis, Inc. Devices and methods for treatment of facet and other joints
US9387079B2 (en) 2001-05-25 2016-07-12 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US9495483B2 (en) 2001-05-25 2016-11-15 Conformis, Inc. Automated Systems for manufacturing patient-specific orthopedic implants and instrumentation

Families Citing this family (193)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050186673A1 (en) * 1995-02-22 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US5940807A (en) * 1996-05-24 1999-08-17 Purcell; Daniel S. Automated and independently accessible inventory information exchange system
US20020173806A1 (en) * 1996-08-30 2002-11-21 Verigen Transplantation Service International (Vtsi) Ag Method for autologous transplantation
US6569172B2 (en) * 1996-08-30 2003-05-27 Verigen Transplantation Service International (Vtsi) Method, instruments, and kit for autologous transplantation
US20060025786A1 (en) * 1996-08-30 2006-02-02 Verigen Transplantation Service International (Vtsi) Ag Method for autologous transplantation
US5989269A (en) * 1996-08-30 1999-11-23 Vts Holdings L.L.C. Method, instruments and kit for autologous transplantation
US9603711B2 (en) 2001-05-25 2017-03-28 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US7618451B2 (en) 2001-05-25 2009-11-17 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
US8771365B2 (en) 2009-02-25 2014-07-08 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs, and related tools
US8617242B2 (en) 2001-05-25 2013-12-31 Conformis, Inc. Implant device and method for manufacture
US7534263B2 (en) 2001-05-25 2009-05-19 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
US10085839B2 (en) 2004-01-05 2018-10-02 Conformis, Inc. Patient-specific and patient-engineered orthopedic implants
US20070100462A1 (en) 2001-05-25 2007-05-03 Conformis, Inc Joint Arthroplasty Devices
US7468075B2 (en) 2001-05-25 2008-12-23 Conformis, Inc. Methods and compositions for articular repair
US8735773B2 (en) 2007-02-14 2014-05-27 Conformis, Inc. Implant device and method for manufacture
US8083745B2 (en) 2001-05-25 2011-12-27 Conformis, Inc. Surgical tools for arthroplasty
US20030180263A1 (en) * 2002-02-21 2003-09-25 Peter Geistlich Resorbable extracellular matrix for reconstruction of bone
US20050186283A1 (en) * 1997-10-10 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US8858981B2 (en) * 1997-10-10 2014-10-14 Ed. Geistlich Soehne Fuer Chemistrie Industrie Bone healing material comprising matrix carrying bone-forming cells
US9034315B2 (en) * 1997-10-10 2015-05-19 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Cell-charged multi-layer collagen membrane
US8563232B2 (en) 2000-09-12 2013-10-22 Lifenet Health Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced
US20080077251A1 (en) * 1999-06-07 2008-03-27 Chen Silvia S Cleaning and devitalization of cartilage
US6293970B1 (en) 1998-06-30 2001-09-25 Lifenet Plasticized bone and soft tissue grafts and methods of making and using same
US20100030340A1 (en) * 1998-06-30 2010-02-04 Wolfinbarger Jr Lloyd Plasticized Grafts and Methods of Making and Using Same
TR200100482T2 (en) * 1998-08-14 2001-06-21 Verigen Transplantation Service International(Vtsi)Ag Methods for chondrocyte cell transplantation; instruments and items
EP1656960A1 (en) * 1998-08-14 2006-05-17 Verigen AG Methods, instruments and materials for chondrocyte cell transplantation
US20020081732A1 (en) 2000-10-18 2002-06-27 Bowlin Gary L. Electroprocessing in drug delivery and cell encapsulation
US7615373B2 (en) 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
US7476250B1 (en) * 1999-04-06 2009-01-13 Mansmann Kevin A Semi-permeable membranes to assist in cartilage repair
US20020095157A1 (en) 1999-07-23 2002-07-18 Bowman Steven M. Graft fixation device combination
US6179840B1 (en) 1999-07-23 2001-01-30 Ethicon, Inc. Graft fixation device and method
DE60018576T2 (en) * 1999-07-28 2006-04-13 Interface Biotech A/S IN VITRO HEALING OF BONE AND / OR TROUBLE DAMAGE
US20020116063A1 (en) * 1999-08-02 2002-08-22 Bruno Giannetti Kit for chondrocyte cell transplantation
CA2391819A1 (en) * 1999-08-02 2001-02-08 Verigen Transplantation Service International Ag Kit for chondrocyte cell transplantation
EP1233707B1 (en) * 1999-12-03 2007-08-08 The University Of Leeds Repair of damaged tissue
US6626945B2 (en) * 2000-03-14 2003-09-30 Chondrosite, Llc Cartilage repair plug
US7678151B2 (en) 2000-05-01 2010-03-16 Ek Steven W System and method for joint resurface repair
AU2001259327B2 (en) * 2000-05-01 2005-02-17 Arthrosurface, Inc. System and method for joint resurface repair
US7713305B2 (en) * 2000-05-01 2010-05-11 Arthrosurface, Inc. Articular surface implant
US6520964B2 (en) * 2000-05-01 2003-02-18 Std Manufacturing, Inc. System and method for joint resurface repair
US6610067B2 (en) 2000-05-01 2003-08-26 Arthrosurface, Incorporated System and method for joint resurface repair
US8177841B2 (en) 2000-05-01 2012-05-15 Arthrosurface Inc. System and method for joint resurface repair
US7163541B2 (en) 2002-12-03 2007-01-16 Arthrosurface Incorporated Tibial resurfacing system
US8366787B2 (en) 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US6638312B2 (en) 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
AU2001288692A1 (en) 2000-09-01 2002-03-13 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed fibrin-based matrices and tissues
WO2002022014A1 (en) 2000-09-14 2002-03-21 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and devising treatment
US6852330B2 (en) * 2000-12-21 2005-02-08 Depuy Mitek, Inc. Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
US20020127265A1 (en) * 2000-12-21 2002-09-12 Bowman Steven M. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
CA2365376C (en) 2000-12-21 2006-03-28 Ethicon, Inc. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
US6599323B2 (en) * 2000-12-21 2003-07-29 Ethicon, Inc. Reinforced tissue implants and methods of manufacture and use
US20040151705A1 (en) * 2002-03-22 2004-08-05 Shuichi Mizuno Neo-cartilage constructs and a method for preparation thereof
US6713085B2 (en) 2001-04-27 2004-03-30 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method and membrane for mucosa regeneration
US8951260B2 (en) 2001-05-25 2015-02-10 Conformis, Inc. Surgical cutting guide
AU2002310193B8 (en) 2001-05-25 2007-05-17 Conformis, Inc. Methods and compositions for articular resurfacing
US8439926B2 (en) 2001-05-25 2013-05-14 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US6723102B2 (en) * 2001-06-14 2004-04-20 Alexandria Research Technologies, Llc Apparatus and method for minimally invasive total joint replacement
US6482209B1 (en) * 2001-06-14 2002-11-19 Gerard A. Engh Apparatus and method for sculpting the surface of a joint
AU2002322567B2 (en) 2001-07-16 2007-09-06 Depuy Products, Inc. Devices form naturally occurring biologically derived
WO2003007787A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Cartilage repair and regeneration device and method
WO2003007786A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Porous delivery scaffold and method
US8025896B2 (en) 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
US7361195B2 (en) 2001-07-16 2008-04-22 Depuy Products, Inc. Cartilage repair apparatus and method
EP1416879A4 (en) * 2001-07-16 2007-04-25 Depuy Products Inc Unitary surgical device and method
EP1416888A4 (en) 2001-07-16 2007-04-25 Depuy Products Inc Meniscus regeneration device and method
US7819918B2 (en) 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
US7914808B2 (en) 2001-07-16 2011-03-29 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
CN1592635A (en) * 2001-09-24 2005-03-09 维里根股份公司 Autologous growth factor cocktail composition, method of production and use
JP4330991B2 (en) * 2001-10-01 2009-09-16 スキャンディウス・バイオメディカル・インコーポレーテッド Apparatus and method for repairing articular cartilage defects
CA2412012C (en) * 2001-11-20 2011-08-02 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage
BR0307033A (en) * 2002-01-22 2004-12-07 Pfizer 3- (imidazolyl) -2-aminopropanoic acids for use as tafi-a inhibitors for the treatment of thrombotic diseases
US7537780B2 (en) * 2002-03-22 2009-05-26 Histogenics Corporation Method for preparing and implanting a cartilage construct to treat cartilage lesions
CA2483660A1 (en) * 2002-05-01 2003-11-13 Verigen Ag Injectable chondrocyte implant
SE0201479D0 (en) * 2002-05-16 2002-05-16 Pharmacia Groningen Bv Kit and method in eye surgery
US20040166169A1 (en) * 2002-07-15 2004-08-26 Prasanna Malaviya Porous extracellular matrix scaffold and method
US20040136968A1 (en) * 2002-09-27 2004-07-15 Verigen Ag Autologous cells on a support matrix for tissue repair
ATE497740T1 (en) * 2002-10-07 2011-02-15 Conformis Inc MINIMALLY INVASIVE JOINT IMPLANT WITH A THREE-DIMENSIONAL GEOMETRY ADAPTED TO THE JOINT SURFACES
US20040078090A1 (en) 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
US7824701B2 (en) 2002-10-18 2010-11-02 Ethicon, Inc. Biocompatible scaffold for ligament or tendon repair
US7799084B2 (en) 2002-10-23 2010-09-21 Mako Surgical Corp. Modular femoral component for a total knee joint replacement for minimally invasive implantation
US20060147332A1 (en) 2004-12-30 2006-07-06 Howmedica Osteonics Corp. Laser-produced porous structure
EP1418013B1 (en) 2002-11-08 2005-01-19 Howmedica Osteonics Corp. Laser-produced porous surface
US7901408B2 (en) 2002-12-03 2011-03-08 Arthrosurface, Inc. System and method for retrograde procedure
AU2003900620A0 (en) * 2003-02-12 2003-02-27 Australian Surgical Design And Manufacture Pty Limited Arthroscopic chondrocyte implantation method and device
US8388624B2 (en) 2003-02-24 2013-03-05 Arthrosurface Incorporated Trochlear resurfacing system and method
US8197837B2 (en) 2003-03-07 2012-06-12 Depuy Mitek, Inc. Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US20050064042A1 (en) * 2003-04-29 2005-03-24 Musculoskeletal Transplant Foundation Cartilage implant plug with fibrin glue and method for implantation
US7488348B2 (en) 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
CA2528399A1 (en) * 2003-06-12 2004-12-23 Interface Biotech A/S A method for cell implantation
US8226715B2 (en) 2003-06-30 2012-07-24 Depuy Mitek, Inc. Scaffold for connective tissue repair
US10583220B2 (en) 2003-08-11 2020-03-10 DePuy Synthes Products, Inc. Method and apparatus for resurfacing an articular surface
US20050046915A1 (en) * 2003-08-22 2005-03-03 Fuji Photo Film Co., Ltd. Hologram recording material composition, hologram recording material and hologram recording method
DE10349722A1 (en) 2003-10-23 2005-06-16 Beschorner, Katharina, Dr. Composition for arthritis / arthritis treatment, in particular of joints
GB0325141D0 (en) * 2003-10-28 2003-12-03 Xiros Plc Repair of damaged tissue on a bone site
US7951163B2 (en) 2003-11-20 2011-05-31 Arthrosurface, Inc. Retrograde excision system and apparatus
WO2005051231A2 (en) 2003-11-20 2005-06-09 Arthrosurface, Inc. Retrograde delivery of resurfacing devices
CA2593182A1 (en) 2003-11-20 2006-07-13 Arthrosurface, Inc. System and method for retrograde procedure
US7316822B2 (en) 2003-11-26 2008-01-08 Ethicon, Inc. Conformable tissue repair implant capable of injection delivery
US7901461B2 (en) 2003-12-05 2011-03-08 Ethicon, Inc. Viable tissue repair implants and methods of use
ATE515245T1 (en) 2003-12-11 2011-07-15 Isto Technologies Inc PARTICLE CARTILAGE SYSTEM
US11395865B2 (en) 2004-02-09 2022-07-26 DePuy Synthes Products, Inc. Scaffolds with viable tissue
EP1576957A1 (en) * 2004-03-18 2005-09-21 Universiteit Twente Tissue repair using pluripotent cells
US8221780B2 (en) 2004-04-20 2012-07-17 Depuy Mitek, Inc. Nonwoven tissue scaffold
US8657881B2 (en) 2004-04-20 2014-02-25 Depuy Mitek, Llc Meniscal repair scaffold
US8137686B2 (en) 2004-04-20 2012-03-20 Depuy Mitek, Inc. Nonwoven tissue scaffold
US7569233B2 (en) * 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
CA2470463C (en) * 2004-06-09 2012-09-18 Lornamead Brands, Inc. Tooth whitening products and methods of making the same
JP2008504107A (en) 2004-06-28 2008-02-14 アースロサーフィス・インコーポレーテッド Joint surface replacement system
CA2541827C (en) * 2004-07-30 2013-05-14 Histogenics Corporation Method for in situ repair of injured, damaged, diseased or aged articular cartilage using neo-cartilage constructs and a method for preparation thereof
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7513866B2 (en) 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
US20060111778A1 (en) * 2004-10-29 2006-05-25 Michalow Alexander E Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway
US7828853B2 (en) 2004-11-22 2010-11-09 Arthrosurface, Inc. Articular surface implant and delivery system
US7354627B2 (en) * 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
CN100384390C (en) * 2005-01-13 2008-04-30 中国人民解放军第三军医大学第一附属医院 Complex tissue of tissue-engineered bone and cartilage and external constructing method thereof
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
WO2007025290A2 (en) 2005-08-26 2007-03-01 Isto Technologies, Inc. Implants and methods for repair, replacement and treatment of joint disease
EP1924146A4 (en) * 2005-09-02 2012-05-02 Interface Biotech As A method for cell implantation
EP1926459B1 (en) 2005-09-19 2015-01-07 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
CN101384230A (en) 2005-11-21 2009-03-11 福特真公司 Devices and methods for treating facet joints, uncovertebral joints, costovertebral joints and other joints
US8728387B2 (en) 2005-12-06 2014-05-20 Howmedica Osteonics Corp. Laser-produced porous surface
EP1803513B1 (en) * 2005-12-30 2017-03-29 Howmedica Osteonics Corp. Method of manufacturing implants using laser
US8623026B2 (en) 2006-02-06 2014-01-07 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools incorporating anatomical relief
CN101420911B (en) 2006-02-06 2012-07-18 康复米斯公司 Patient selectable arthroplasty device and surjical tool
US20070288021A1 (en) * 2006-06-07 2007-12-13 Howmedica Osteonics Corp. Flexible joint implant
US8147861B2 (en) * 2006-08-15 2012-04-03 Howmedica Osteonics Corp. Antimicrobial implant
DE07825069T1 (en) * 2006-09-07 2010-04-08 Ed Geistlich Söhne Ag Für Chemische Industrie METHOD FOR THE TREATMENT OF BONE CANCER
KR20080037883A (en) * 2006-10-27 2008-05-02 세원셀론텍(주) Using method and medical kit
EP2136717B1 (en) 2006-12-11 2013-10-16 Arthrosurface Incorporated Retrograde resection apparatus
US7871440B2 (en) 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US7758643B2 (en) * 2007-02-26 2010-07-20 Biomet Sports Medicine, Llc Stable cartilage defect repair plug
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
WO2008128075A1 (en) 2007-04-12 2008-10-23 Isto Technologies, Inc. Compositions and methods for tissue repair
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
US9125743B2 (en) * 2007-07-16 2015-09-08 Lifenet Health Devitalization and recellularization of cartilage
US20090024224A1 (en) 2007-07-16 2009-01-22 Chen Silvia S Implantation of cartilage
WO2009014718A1 (en) 2007-07-24 2009-01-29 Porex Corporation Porous laser sintered articles
WO2009026392A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation A method for improvement of differentiation of mesenchymal stem cells using a double-structured tissue implant
CA2701884A1 (en) * 2007-10-15 2009-04-23 Wake Forest University Health Sciences Methods and compositions for printing biologically compatible nanotube composites of autologous tissue
EP2291205A2 (en) * 2008-02-29 2011-03-09 Coloplast A/S Compositions and methods for augmentation and regeneration of living tissue in a subject
CA2713118A1 (en) * 2008-02-29 2009-09-03 Interface Biotech A/S Biosynthetic cartilaginous matrix and methods for their production
WO2009111481A1 (en) 2008-03-03 2009-09-11 Arthrosurface Incorporated Bone resurfacing system and method
EP2265220A1 (en) 2008-03-05 2010-12-29 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
GB0812631D0 (en) * 2008-07-10 2008-08-20 Imp Innovations Ltd Modular knee implants
US8808297B2 (en) 2009-02-24 2014-08-19 Microport Orthopedics Holdings Inc. Orthopedic surgical guide
US9017334B2 (en) 2009-02-24 2015-04-28 Microport Orthopedics Holdings Inc. Patient specific surgical guide locator and mount
US8808303B2 (en) 2009-02-24 2014-08-19 Microport Orthopedics Holdings Inc. Orthopedic surgical guide
JP2012523897A (en) 2009-04-16 2012-10-11 コンフォーミス・インコーポレイテッド Patient-specific joint replacement device for ligament repair
US9662126B2 (en) 2009-04-17 2017-05-30 Arthrosurface Incorporated Glenoid resurfacing system and method
WO2010121246A1 (en) 2009-04-17 2010-10-21 Arthrosurface Incorporated Glenoid resurfacing system and method
WO2016154393A1 (en) 2009-04-17 2016-09-29 Arthrosurface Incorporated Glenoid repair system and methods of use thereof
AU2011222404A1 (en) 2010-03-05 2012-09-27 Arthrosurface Incorporated Tibial resurfacing system and method
US8895291B2 (en) 2010-10-08 2014-11-25 Terumo Bct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
US9066716B2 (en) 2011-03-30 2015-06-30 Arthrosurface Incorporated Suture coil and suture sheath for tissue repair
WO2013081071A1 (en) * 2011-12-02 2013-06-06 テルモ株式会社 Device for cell transplantation
EP2804565B1 (en) 2011-12-22 2018-03-07 Arthrosurface Incorporated System for bone fixation
US9364896B2 (en) 2012-02-07 2016-06-14 Medical Modeling Inc. Fabrication of hybrid solid-porous medical implantable devices with electron beam melting technology
US9180010B2 (en) 2012-04-06 2015-11-10 Howmedica Osteonics Corp. Surface modified unit cell lattice structures for optimized secure freeform fabrication
US9135374B2 (en) 2012-04-06 2015-09-15 Howmedica Osteonics Corp. Surface modified unit cell lattice structures for optimized secure freeform fabrication
US9486226B2 (en) 2012-04-18 2016-11-08 Conformis, Inc. Tibial guides, tools, and techniques for resecting the tibial plateau
US9186053B2 (en) * 2012-05-03 2015-11-17 Covidien Lp Methods of using light to repair hernia defects
US9675471B2 (en) 2012-06-11 2017-06-13 Conformis, Inc. Devices, techniques and methods for assessing joint spacing, balancing soft tissues and obtaining desired kinematics for joint implant components
US9468448B2 (en) 2012-07-03 2016-10-18 Arthrosurface Incorporated System and method for joint resurfacing and repair
US10016527B2 (en) 2012-10-23 2018-07-10 Orthovita, Inc. Materials and methods for repair of cartilage defects
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
US9492200B2 (en) 2013-04-16 2016-11-15 Arthrosurface Incorporated Suture system and method
PL2853384T3 (en) * 2013-09-27 2017-06-30 Skulle Implants Oy A method for coating and a coated surface
EP3068867B1 (en) 2013-11-16 2018-04-18 Terumo BCT, Inc. Expanding cells in a bioreactor
US10624748B2 (en) 2014-03-07 2020-04-21 Arthrosurface Incorporated System and method for repairing articular surfaces
US20150250472A1 (en) 2014-03-07 2015-09-10 Arthrosurface Incorporated Delivery System for Articular Surface Implant
US11607319B2 (en) 2014-03-07 2023-03-21 Arthrosurface Incorporated System and method for repairing articular surfaces
JP6783143B2 (en) 2014-03-25 2020-11-11 テルモ ビーシーティー、インコーポレーテッド Passive replenishment of medium
US20160090569A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled Feed
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CA2985398C (en) * 2015-05-08 2021-08-03 Reoss Gmbh Device for covering and/or reconstructing a bone defect site; method for producing a cap of a covering device for a bone defect site
US20160331539A1 (en) * 2015-05-12 2016-11-17 Elwha Llc Modifiable implants
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
EP3656841A1 (en) 2017-03-31 2020-05-27 Terumo BCT, Inc. Cell expansion
AU2018203479A1 (en) 2017-05-18 2018-12-06 Howmedica Osteonics Corp. High fatigue strength porous structure
WO2019028344A1 (en) 2017-08-04 2019-02-07 Arthrosurface Incorporated Multicomponent articular surface implant
GB2567173A (en) * 2017-10-04 2019-04-10 Univ Oxford Innovation Ltd Cartilage plug
DE102018113580A1 (en) * 2018-06-07 2019-12-12 Christoph Karl METHOD AND DEVICE FOR PRODUCING AN IMPLANT
GB2609338B (en) 2019-03-12 2023-06-14 Arthrosurface Inc Humeral and glenoid articular surface implant systems and methods
US11523834B1 (en) 2022-06-20 2022-12-13 University Of Utah Research Foundation Cartilage and bone harvest and delivery system and methods
US11660194B1 (en) 2022-06-20 2023-05-30 University Of Utah Research Foundation Cartilage and bone harvest and delivery system and methods

Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559936A (en) * 1983-09-29 1985-12-24 Hill Edward B Bone plugging apparatus
US4642120A (en) * 1983-03-23 1987-02-10 Ramot University Authority For Applied Research And Industrial Development Ltd. Repair of cartilage and bones
US4649918A (en) * 1980-09-03 1987-03-17 Custom Medical Devices, Inc. Bone core removing tool
US4846835A (en) * 1987-06-15 1989-07-11 Grande Daniel A Technique for healing lesions in cartilage
US4877020A (en) * 1984-11-30 1989-10-31 Vich Jose M O Apparatus for bone graft
US5019108A (en) * 1990-02-02 1991-05-28 Bertin Kim C Modular implant
US5062845A (en) * 1989-05-10 1991-11-05 Spine-Tech, Inc. Method of making an intervertebral reamer
US5067964A (en) * 1989-12-13 1991-11-26 Stryker Corporation Articular surface repair
WO1992022312A1 (en) * 1991-06-17 1992-12-23 Wadstroem Jonas Tissue treatment composition comprising fibrin or fibrinogen and biodegradable and biocompatible polymer
EP0530804A1 (en) * 1991-09-06 1993-03-10 Shaw, Robert Francis Kits and compositions for the treatment and repair of defects or lesions in cartilage or bone
WO1993011723A1 (en) * 1991-12-17 1993-06-24 Regen Biologics, Inc. Prosthetic articular cartilage
WO1994000484A1 (en) * 1992-06-22 1994-01-06 Young Henry E Scar inhibitory factor and use thereof
WO1994009722A1 (en) * 1988-03-14 1994-05-11 Thm Biomedical, Inc. Method and device for reconstruction of articular cartilage
US5403338A (en) * 1992-01-21 1995-04-04 Scanlan International, Inc. Punch for opening passages between two compartments
WO1995030383A1 (en) * 1994-05-05 1995-11-16 Genzyme Corporation Methods and compositions for the repair of articular cartilage defects in mammals
DE4425456A1 (en) * 1994-09-07 1996-03-21 Matthias Dr Med Honl Bone saw for concentric cylindrical or part spherical cuts

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH632922A5 (en) 1978-10-06 1982-11-15 Sulzer Ag Anchorage pin for bone implants
ATE4440T1 (en) 1980-02-21 1983-08-15 J. & P. Coats, Limited DEVICE FOR TREATMENT OF DAMAGED SURFACES OF HUMAN JOINTS.
US4553272A (en) 1981-02-26 1985-11-19 University Of Pittsburgh Regeneration of living tissues by growth of isolated cells in porous implant and product thereof
US4393874A (en) 1982-04-26 1983-07-19 Telectronics Pty. Ltd. Bradycardia event counting and reporting pacer
WO1985001651A1 (en) * 1983-10-20 1985-04-25 Vettivetpillai Ketharanathan Biomaterial
US4620327A (en) 1984-07-05 1986-11-04 Caplan Arnold I Process of adapting soluble bone protein for use in stimulating osteoinduction
US4789663A (en) * 1984-07-06 1988-12-06 Collagen Corporation Methods of bone repair using collagen
US4642117A (en) 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
US5902741A (en) 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US5041138A (en) 1986-11-20 1991-08-20 Massachusetts Institute Of Technology Neomorphogenesis of cartilage in vivo from cell culture
US5736372A (en) 1986-11-20 1998-04-07 Massachusetts Institute Of Technology Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure
NL8700113A (en) * 1987-01-19 1988-08-16 Groningen Science Park INK, SUITABLE FOR TREATMENT BY RECONSTRUCTIVE SURGERY, WITH TISSUE-SPECIFIC POROSITY, AND METHOD FOR MANUFACTURING THE ENTAGMENT.
GB8705985D0 (en) 1987-03-13 1987-04-15 Geistlich Soehne Ag Dressings
US5158574A (en) 1987-07-20 1992-10-27 Regen Corporation Prosthetic meniscus
US5258043A (en) 1987-07-20 1993-11-02 Regen Corporation Method for making a prosthetic intervertebral disc
US5116374A (en) 1989-03-02 1992-05-26 Regen Corporation Prosthetic meniscus
CA1329089C (en) 1987-09-02 1994-05-03 Russell Warren Surgical fastener
NZ226170A (en) 1987-09-18 1990-07-26 Ethicon Inc Stable freeze-dried pharmaceutical composition containing epidermal growth factor
WO1989004646A1 (en) 1987-11-13 1989-06-01 Jefferies Steven R Bone repair material and delayed drug delivery
JP2645098B2 (en) * 1988-09-06 1997-08-25 テルモ株式会社 Antibacterial agent-containing artificial skin and method for producing the same
US5201745A (en) * 1988-03-15 1993-04-13 Imedex Visceral surgery patch
US4975526A (en) 1989-02-23 1990-12-04 Creative Biomolecules, Inc. Bone collagen matrix for zenogenic implants
US4904259A (en) * 1988-04-29 1990-02-27 Samuel Itay Compositions and methods for repair of cartilage and bone
US5053050A (en) * 1988-04-29 1991-10-01 Samuel Itay Compositions for repair of cartilage and bone
US5108436A (en) 1988-09-29 1992-04-28 Collagen Corporation Implant fixation
IE61346B1 (en) 1988-11-02 1994-11-02 Genentech Inc A permeable material to fit around the teeth or gums of a mammal
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5092883A (en) * 1988-12-28 1992-03-03 Eppley Barry L Method for promoting soft connective tissue growth and repair in mammals
WO1990009783A1 (en) 1989-02-22 1990-09-07 Massachusetts Institute Of Technology Delivery system for controlled release of bioactive factors
AU5654990A (en) 1989-04-28 1990-11-29 Brigham And Women's Hospital Novel materials and methods for guided tissue regeneration
US5129906A (en) 1989-09-08 1992-07-14 Linvatec Corporation Bioabsorbable tack for joining bodily tissue and in vivo method and apparatus for deploying same
US6413511B1 (en) * 1990-12-20 2002-07-02 University Of Pittsburgh Of The Commonwealth System Of Higher Education Cartilage alterations by administering to joints chondrocytes comprising a heterologous polynucleotide
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
US5853746A (en) * 1991-01-31 1998-12-29 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone using functional barrier
US5206028A (en) 1991-02-11 1993-04-27 Li Shu Tung Dense collagen membrane matrices for medical uses
FR2679778B1 (en) 1991-08-02 1995-07-07 Coletica USE OF CROLAGEN CROSSLINKED BY A CROSSLINKING AGENT FOR THE MANUFACTURE OF A SLOW RESORPTIVE, BIOCOMPATIBLE, SUTURABLE MEMBRANE, AS WELL AS SUCH A MEMBRANE.
US5259835A (en) * 1991-08-29 1993-11-09 Tri-Point Medical L.P. Wound closure means and method using flowable adhesive
DE69307299T2 (en) * 1992-02-14 1997-04-30 Univ Texas MULTI-PHASE, BIODEGRADABLE IMPLANT / CARRIER AND METHOD FOR THE PRODUCTION THEREOF
US5326357A (en) 1992-03-18 1994-07-05 Mount Sinai Hospital Corporation Reconstituted cartridge tissue
WO1994009118A1 (en) 1992-10-13 1994-04-28 The General Hospital Corporation Immortalized human chondrocytes
US5455597A (en) * 1992-12-29 1995-10-03 Canon Kabushiki Kaisha Image-forming apparatus, and designation of electron beam diameter at image-forming member in image-forming apparatus
DE4300039C1 (en) 1993-01-04 1994-06-09 Imz Fertigung Vertrieb Fixture nail for attachment of cover membrane to bone surrounding defect point filled with bone structural material - has nail head of large dia. and shaft of smaller dia. which has cylindrical retention part and conical point part
US5514378A (en) * 1993-02-01 1996-05-07 Massachusetts Institute Of Technology Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
DE4431598C2 (en) 1993-03-03 1997-03-20 Michael Sittinger Process for producing an implant from cell cultures
DE4306661C2 (en) 1993-03-03 1995-04-20 Michael Dipl Biol Sittinger Process for producing an implant from cell cultures
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
DE4317448A1 (en) * 1993-05-19 1994-11-24 Gross Ulrich Joint replacement
CA2130295A1 (en) 1993-08-26 1995-02-27 Richard A. Berg Ionically crosslinked glycosaminoglycan gels for soft tissue augmentation and drug delivery
US5423858A (en) 1993-09-30 1995-06-13 United States Surgical Corporation Septoplasty fasteners and device for applying same
GB9400163D0 (en) 1994-01-06 1994-03-02 Geistlich Soehne Ag Membrane
US5354283A (en) 1994-01-07 1994-10-11 Little Rapids Corporation Trocar retention apparatus
CA2142209A1 (en) 1994-03-29 1995-09-30 George H. Chu Collagen implants having improved tensile properties
US5858781A (en) * 1994-05-13 1999-01-12 Matyas; John R. Method of tissue transfer and retrieval
EP0692227A1 (en) 1994-07-11 1996-01-17 SULZER Medizinaltechnik AG Sheet implant
ZA956249B (en) 1994-07-28 1996-05-10 Ivan Vesely Bioprosthetic implants and method of making and using same
US5769899A (en) 1994-08-12 1998-06-23 Matrix Biotechnologies, Inc. Cartilage repair unit
US5569252A (en) 1994-09-27 1996-10-29 Justin; Daniel F. Device for repairing a meniscal tear in a knee and method
US6080194A (en) 1995-02-10 2000-06-27 The Hospital For Joint Disease Orthopaedic Institute Multi-stage collagen-based template or implant for use in the repair of cartilage lesions
US5713374A (en) * 1995-02-10 1998-02-03 The Hospital For Joint Diseases Orthopaedic Institute Fixation method for the attachment of wound repair materials to cartilage defects
GB9721585D0 (en) 1997-10-10 1997-12-10 Geistlich Soehne Ag Chemical product
GB9503492D0 (en) 1995-02-22 1995-04-12 Ed Geistlich S Hne A G F R Che Chemical product
US6132463A (en) * 1995-05-19 2000-10-17 Etex Corporation Cell seeding of ceramic compositions
WO1997004665A1 (en) 1995-07-31 1997-02-13 Alta Spinner Australia Pty. Limited Surface moisture removal from food products
US5659252A (en) * 1995-08-25 1997-08-19 Sony Corporation Apparatus and method for detecting arcing in a CRT
DE19540487A1 (en) 1995-10-20 1997-04-24 Olaf Schultz Cell interaction system for induction of artificial 3-dimensional tissue
WO1997015655A2 (en) 1995-10-20 1997-05-01 Michael Sittinger New artificial tissue, method for the production and the use thereof
DE19601477C2 (en) 1996-01-17 1999-12-16 Axel Kirsch Fastening nail
US5842477A (en) 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
DE19654884C2 (en) 1996-03-04 1999-07-29 Kirsch Axel Molded body
ES2210526T3 (en) 1996-06-04 2004-07-01 Centerpulse Biologics Inc. CARTILAGO PRODUCTION PROCEDURE.
US5989269A (en) * 1996-08-30 1999-11-23 Vts Holdings L.L.C. Method, instruments and kit for autologous transplantation
EP0842670A1 (en) 1996-11-13 1998-05-20 Katsunari Nishihara Biomedical materials
US6187053B1 (en) 1996-11-16 2001-02-13 Will Minuth Process for producing a natural implant
DE19648876C2 (en) 1996-11-16 1999-10-07 Will Minuth Method of making a natural implant
AU6654598A (en) 1997-02-13 1998-09-08 Benedict, James A. Implantable collagen-containing putty material
DE19957388A1 (en) 1999-11-24 2001-06-13 Michael Sittinger Chondroinductive and implantable substrates for cartilage healing and protection
DE10006822A1 (en) 2000-02-08 2001-08-23 Michael Sittinger Artificial bone chips, processes for their production and their use

Patent Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649918A (en) * 1980-09-03 1987-03-17 Custom Medical Devices, Inc. Bone core removing tool
US4642120A (en) * 1983-03-23 1987-02-10 Ramot University Authority For Applied Research And Industrial Development Ltd. Repair of cartilage and bones
US4559936A (en) * 1983-09-29 1985-12-24 Hill Edward B Bone plugging apparatus
US4877020A (en) * 1984-11-30 1989-10-31 Vich Jose M O Apparatus for bone graft
US4846835A (en) * 1987-06-15 1989-07-11 Grande Daniel A Technique for healing lesions in cartilage
WO1994009722A1 (en) * 1988-03-14 1994-05-11 Thm Biomedical, Inc. Method and device for reconstruction of articular cartilage
US5062845A (en) * 1989-05-10 1991-11-05 Spine-Tech, Inc. Method of making an intervertebral reamer
US5067964A (en) * 1989-12-13 1991-11-26 Stryker Corporation Articular surface repair
US5019108A (en) * 1990-02-02 1991-05-28 Bertin Kim C Modular implant
WO1992022312A1 (en) * 1991-06-17 1992-12-23 Wadstroem Jonas Tissue treatment composition comprising fibrin or fibrinogen and biodegradable and biocompatible polymer
EP0530804A1 (en) * 1991-09-06 1993-03-10 Shaw, Robert Francis Kits and compositions for the treatment and repair of defects or lesions in cartilage or bone
WO1993011723A1 (en) * 1991-12-17 1993-06-24 Regen Biologics, Inc. Prosthetic articular cartilage
US5403338A (en) * 1992-01-21 1995-04-04 Scanlan International, Inc. Punch for opening passages between two compartments
WO1994000484A1 (en) * 1992-06-22 1994-01-06 Young Henry E Scar inhibitory factor and use thereof
WO1995030383A1 (en) * 1994-05-05 1995-11-16 Genzyme Corporation Methods and compositions for the repair of articular cartilage defects in mammals
DE4425456A1 (en) * 1994-09-07 1996-03-21 Matthias Dr Med Honl Bone saw for concentric cylindrical or part spherical cuts

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9020788B2 (en) 1997-01-08 2015-04-28 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
USRE43282E1 (en) 1998-09-14 2012-03-27 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and devising treatment
US9286686B2 (en) 1998-09-14 2016-03-15 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and assessing cartilage loss
US8862202B2 (en) 1998-09-14 2014-10-14 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and preventing damage
US8926706B2 (en) 2001-05-25 2015-01-06 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US9333085B2 (en) 2001-05-25 2016-05-10 Conformis, Inc. Patient selectable knee arthroplasty devices
US9495483B2 (en) 2001-05-25 2016-11-15 Conformis, Inc. Automated Systems for manufacturing patient-specific orthopedic implants and instrumentation
US8945230B2 (en) 2001-05-25 2015-02-03 Conformis, Inc. Patient selectable knee joint arthroplasty devices
US8906107B2 (en) 2001-05-25 2014-12-09 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US8974539B2 (en) 2001-05-25 2015-03-10 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US8882847B2 (en) 2001-05-25 2014-11-11 Conformis, Inc. Patient selectable knee joint arthroplasty devices
US9439767B2 (en) 2001-05-25 2016-09-13 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US9186254B2 (en) 2001-05-25 2015-11-17 Conformis, Inc. Patient selectable knee arthroplasty devices
US8690945B2 (en) 2001-05-25 2014-04-08 Conformis, Inc. Patient selectable knee arthroplasty devices
US9308091B2 (en) 2001-05-25 2016-04-12 Conformis, Inc. Devices and methods for treatment of facet and other joints
US9387079B2 (en) 2001-05-25 2016-07-12 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US8965088B2 (en) 2002-11-07 2015-02-24 Conformis, Inc. Methods for determining meniscal size and shape and for devising treatment
US8932363B2 (en) 2002-11-07 2015-01-13 Conformis, Inc. Methods for determining meniscal size and shape and for devising treatment
US9180015B2 (en) 2008-03-05 2015-11-10 Conformis, Inc. Implants for altering wear patterns of articular surfaces
US9320620B2 (en) 2009-02-24 2016-04-26 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools

Also Published As

Publication number Publication date
DK1181908T3 (en) 2004-04-13
CZ297248B6 (en) 2006-10-11
EP1181908A1 (en) 2002-02-27
EP1006950A2 (en) 2000-06-14
DE69726896T2 (en) 2004-10-28
AU4171097A (en) 1998-03-19
SG119137A1 (en) 2006-02-28
PT1384452E (en) 2009-07-02
NZ334400A (en) 2001-01-26
HU225952B1 (en) 2008-01-28
SK285075B6 (en) 2006-05-04
KR100686412B1 (en) 2007-02-23
CA2419644C (en) 2009-10-13
DE69728569T2 (en) 2005-04-07
TR200102871T2 (en) 2002-06-21
MXPA99001794A (en) 2002-05-06
EP1006950B1 (en) 2004-04-07
CA2264138C (en) 2003-05-27
ES2325206T3 (en) 2009-08-28
NO990933D0 (en) 1999-02-26
TR199900437T2 (en) 1999-05-21
US20030195532A1 (en) 2003-10-16
CN1500447A (en) 2004-06-02
US6599300B2 (en) 2003-07-29
PT1006950E (en) 2004-08-31
EP1181908B1 (en) 2003-12-17
US20020091396A1 (en) 2002-07-11
US5989269A (en) 1999-11-23
EP1384452B1 (en) 2009-04-15
SG120854A1 (en) 2006-04-26
CZ58799A3 (en) 2000-05-17
US6283980B1 (en) 2001-09-04
WO1998008469A2 (en) 1998-03-05
IL128580A (en) 2007-09-20
IL128580A0 (en) 2000-01-31
US20060195122A1 (en) 2006-08-31
SI1384452T1 (en) 2009-10-31
DK200200178U1 (en) 2002-06-04
DK1384452T3 (en) 2009-07-27
RU2002103570A (en) 2003-10-10
DE29724585U1 (en) 2002-05-16
JP2007296371A (en) 2007-11-15
CN1200656C (en) 2005-05-11
BR9711967A (en) 2000-01-18
JP2002502272A (en) 2002-01-22
DE69739363D1 (en) 2009-05-28
RU2214197C2 (en) 2003-10-20
EP1459709A1 (en) 2004-09-22
ATE263524T1 (en) 2004-04-15
CA2419644A1 (en) 1998-03-05
ES2218697T3 (en) 2004-11-16
JP2003159266A (en) 2003-06-03
NO990933L (en) 1999-02-26
DE69726896D1 (en) 2004-01-29
US6599301B2 (en) 2003-07-29
KR20000035886A (en) 2000-06-26
AU731162B2 (en) 2001-03-22
EP1384452A1 (en) 2004-01-28
HK1063003A1 (en) 2004-12-10
US7048750B2 (en) 2006-05-23
ATE428376T1 (en) 2009-05-15
HUP0002980A2 (en) 2001-01-29
US6592598B2 (en) 2003-07-15
SI1006950T1 (en) 2004-12-31
PL331834A1 (en) 1999-08-02
PT1181908E (en) 2004-04-30
DK200200177U1 (en) 2002-06-04
US20020151912A1 (en) 2002-10-17
US6379367B1 (en) 2002-04-30
US20020116015A1 (en) 2002-08-22
KR20030097603A (en) 2003-12-31
CN1241918A (en) 2000-01-19
NZ508145A (en) 2002-07-26
US6592599B2 (en) 2003-07-15
DK1006950T3 (en) 2004-07-19
HU0400358D0 (en) 2004-05-28
ATE256443T1 (en) 2004-01-15
NZ518474A (en) 2003-09-26
TR200102883T2 (en) 2002-06-21
DE69728569D1 (en) 2004-05-13
SK24099A3 (en) 2001-03-12
ES2211722T3 (en) 2004-07-16
HUP0002980A3 (en) 2001-02-28
CA2264138A1 (en) 1998-03-05
US20020116014A1 (en) 2002-08-22
HK1025035A1 (en) 2000-11-03

Similar Documents

Publication Publication Date Title
WO1998008469A3 (en) Method, instruments and kit for autologous transplantation
EP1416944A4 (en) Composition for treatment of articular cartilage damage
AU2003302074A1 (en) Methods of inducing or enhancing cartilage repair
AU7215794A (en) Method of regenerating articular cartilage
EP1441028A3 (en) Cell cultivation method for the preparation of chondrocytes/chondroblasts
AU9588098A (en) Environmentally benign anti-icing or deicing fluids
WO1998051354A3 (en) Compositions for morphogen-induced osteogenesis
AU2468995A (en) Methods and compositions for the repair of articular cartilage defects in mammals
AU4985899A (en) Method of removing carbon from fly ash
AU1256395A (en) Hepatoblasts and method of isolating same
AU1034797A (en) Improvements to methods for rehabilitating suspension bridges, and to bridges thereby rehabilitated
WO2001008610A8 (en) Kit for chondrocyte cell transplantation
EP1142989A3 (en) Chondrocyte cell-lines
RU98109330A (en) METHOD FOR REMOVING JOINT Cartilage
AU4110997A (en) Method for the renovation of pipelines
HUP9601671A3 (en) Biological method for replacement of soil fertility with inoculation
HU9904484D0 (en) Method for recycling of used plant oil

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 97199207.X

Country of ref document: CN

AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE HU IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK TJ TM TR TT UA UG US UZ VN AM AZ BY KG KZ MD RU TJ TM

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH KE LS MW SD SZ UG ZW AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: PV1999-587

Country of ref document: CZ

WWE Wipo information: entry into national phase

Ref document number: PA/a/1999/001794

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 24099

Country of ref document: SK

ENP Entry into the national phase

Ref document number: 2264138

Country of ref document: CA

Ref document number: 2264138

Country of ref document: CA

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 1019997001597

Country of ref document: KR

Ref document number: 334400

Country of ref document: NZ

Ref document number: 1999/00437

Country of ref document: TR

WWE Wipo information: entry into national phase

Ref document number: 1997939677

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: PV1999-587

Country of ref document: CZ

WWP Wipo information: published in national office

Ref document number: 1997939677

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1019997001597

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: 2001/02883

Country of ref document: TR

Ref document number: 2001/02871

Country of ref document: TR

WWE Wipo information: entry into national phase

Ref document number: 2003/00134

Country of ref document: TR

WWG Wipo information: grant in national office

Ref document number: 1997939677

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: PV1999-587

Country of ref document: CZ

WWG Wipo information: grant in national office

Ref document number: 1019997001597

Country of ref document: KR