WO1998006415A3 - Anti-chlamydial methods and materials - Google Patents
Anti-chlamydial methods and materials Download PDFInfo
- Publication number
- WO1998006415A3 WO1998006415A3 PCT/US1997/013810 US9713810W WO9806415A3 WO 1998006415 A3 WO1998006415 A3 WO 1998006415A3 US 9713810 W US9713810 W US 9713810W WO 9806415 A3 WO9806415 A3 WO 9806415A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- chlamydial
- materials
- chlamydial infection
- bpi
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1751—Bactericidal/permeability-increasing protein [BPI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT97936420T ATE226442T1 (en) | 1996-08-09 | 1997-08-07 | ANTI-CHLAMYDIA METHODS AND MEANS |
AU39094/97A AU741480B2 (en) | 1996-08-09 | 1997-08-07 | Anti-chlamydial methods and materials |
JP10509836A JP2001500117A (en) | 1996-08-09 | 1997-08-07 | Anti-Chlamydia methods and substances |
CA002263181A CA2263181C (en) | 1996-08-09 | 1997-08-07 | Anti-chlamydial methods and materials |
EP97936420A EP0918533B1 (en) | 1996-08-09 | 1997-08-07 | Anti-chlamydial methods and materials |
NZ334041A NZ334041A (en) | 1996-08-09 | 1997-08-07 | Anti-chlamydial activity of BPI (bactericidal/permeability increasing proteins) protein products against chlamydia infected host cells |
DE69716605T DE69716605T2 (en) | 1996-08-09 | 1997-08-07 | ANTI-CHLAMYDIA METHOD AND MEANS |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/694,843 US5888973A (en) | 1996-08-09 | 1996-08-09 | Anti-chlamydial uses of BPI protein products |
US08/694,843 | 1996-08-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998006415A2 WO1998006415A2 (en) | 1998-02-19 |
WO1998006415A3 true WO1998006415A3 (en) | 1998-05-14 |
Family
ID=24790487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/013810 WO1998006415A2 (en) | 1996-08-09 | 1997-08-07 | Anti-chlamydial methods and materials |
Country Status (10)
Country | Link |
---|---|
US (3) | US5888973A (en) |
EP (1) | EP0918533B1 (en) |
JP (1) | JP2001500117A (en) |
CN (1) | CN1232401A (en) |
AT (1) | ATE226442T1 (en) |
AU (1) | AU741480B2 (en) |
CA (1) | CA2263181C (en) |
DE (1) | DE69716605T2 (en) |
NZ (1) | NZ334041A (en) |
WO (1) | WO1998006415A2 (en) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5198541A (en) * | 1987-08-11 | 1993-03-30 | New York University | Dna encoding bactericidal/permeability-increasing proteins |
US5888973A (en) * | 1996-08-09 | 1999-03-30 | Xoma Corporation | Anti-chlamydial uses of BPI protein products |
WO1998006435A2 (en) * | 1996-08-14 | 1998-02-19 | Vanderbilt University | COMPOSITIONS OF ANTICHLAMYDIAL AGENTS FOR THE DIAGNOSIS AND MANAGEMENT OF INFECTION CAUSED BY $i(CHLAMYDIA) |
US6482796B2 (en) | 1996-11-01 | 2002-11-19 | Xoma Corporation | Therapeutic uses of N-terminal BPI protein products in ANCA-positive patients |
US6884784B1 (en) * | 1997-05-06 | 2005-04-26 | Vanderbilt University | Diagnosis and management of infection caused by chlamydia |
US6093573A (en) * | 1997-06-20 | 2000-07-25 | Xoma | Three-dimensional structure of bactericidal/permeability-increasing protein (BPI) |
US6013631A (en) * | 1998-06-19 | 2000-01-11 | Xoma Corporation | Bactericidal/permeability-increasing protein (BPI) deletion analogs |
US6310073B1 (en) * | 1998-07-28 | 2001-10-30 | Queen's University At Kingston | Methods and compositions to treat glycosaminoglycan-associated molecular interactions |
US6239113B1 (en) * | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
US7056893B2 (en) * | 1999-03-31 | 2006-06-06 | Insite Vision, Inc. | Topical treatment for prevention of ocular infections |
US6153584A (en) * | 1999-04-01 | 2000-11-28 | Levy; Ofer | Therapeutic uses of BPI protein products in BPI-deficient humans |
US7041644B2 (en) | 1999-04-01 | 2006-05-09 | Xoma Technology | Therapeutic uses of BPI protein products in BPI-deficient humans |
US20020173464A1 (en) * | 2000-12-01 | 2002-11-21 | King George L. | Modulation of pericyte proliferation |
AU2003239438A1 (en) * | 2002-05-15 | 2003-12-02 | University Of Washintgon | Method of screening anti-bacterial agents for effectiveness in treating persistent intracellular infections |
US20050014932A1 (en) * | 2003-05-15 | 2005-01-20 | Iogenetics, Llc | Targeted biocides |
US8703134B2 (en) | 2003-05-15 | 2014-04-22 | Iogenetics, Llc | Targeted cryptosporidium biocides |
US8394379B2 (en) * | 2003-05-15 | 2013-03-12 | Iogenetics, Llc | Targeted cryptosporidium biocides |
US20060046970A1 (en) * | 2004-08-31 | 2006-03-02 | Insite Vision Incorporated | Topical otic compositions and methods of topical treatment of prevention of otic infections |
WO2006113526A2 (en) * | 2005-04-15 | 2006-10-26 | The Regents Of The University Of California | Prevention of chlamydia infection using a protective antibody |
EP1741440A1 (en) | 2005-07-08 | 2007-01-10 | Mellitus S.L. | Use of BPI protein for the treatment of disorders of the metabolism and cardiovascular disorders |
GB201319620D0 (en) | 2013-11-06 | 2013-12-18 | Norwegian University Of Science And Technology | Immunosuppressive agents and their use in therapy |
GB201319621D0 (en) | 2013-11-06 | 2013-12-18 | Norwegian University Of Science And Technology | Antimicrobial agents and their use in therapy |
US10602795B2 (en) | 2017-01-26 | 2020-03-31 | Bell Sports, Inc. | Helmet comprising a segmented shell |
Citations (4)
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WO1989001486A1 (en) * | 1987-08-11 | 1989-02-23 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
WO1995024209A1 (en) * | 1994-03-11 | 1995-09-14 | Xoma Corporation | Therapeutic uses of bactericidal/permeability-increasing protein dimer products |
WO1996001647A1 (en) * | 1994-07-11 | 1996-01-25 | Xoma Corporation | Anti-protozoan methods and materials |
WO1996021436A1 (en) * | 1995-01-13 | 1996-07-18 | Xoma Corporation | Improved therapeutic compositions comprising bactericidal/permeability-increasing (bpi) protein products |
Family Cites Families (44)
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---|---|---|---|---|
US5576292A (en) * | 1987-08-11 | 1996-11-19 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
US5198541A (en) * | 1987-08-11 | 1993-03-30 | New York University | Dna encoding bactericidal/permeability-increasing proteins |
US5171739A (en) * | 1989-02-14 | 1992-12-15 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and preventation thereof using a BPI protein |
US5334584A (en) * | 1989-02-14 | 1994-08-02 | Incyte Pharamaceuticals, Inc. | Recombinant, non-glycosylated bpi protein and uses thereof |
US5089274A (en) * | 1989-02-14 | 1992-02-18 | Incyte Pharmaceuticals, Inc. | Use of bactericidal/permeability increasing protein or biologically active analogs thereof to treat endotoxin-related disorders |
US5234912A (en) * | 1989-02-14 | 1993-08-10 | Incyte Pharmaceuticals, Inc. | Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof |
US5308834A (en) * | 1989-02-14 | 1994-05-03 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and prevention thereof using a BPI protein |
EP0563222B1 (en) * | 1990-12-03 | 1998-02-25 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
EP0605653A4 (en) * | 1991-09-26 | 1995-03-15 | Incyte Pharma Inc | A new form of liposaccharide binding protein (lbp). |
US5643570A (en) * | 1992-05-19 | 1997-07-01 | Xoma Corporation | BPI-immunoglobulin fusion proteins |
ES2132239T3 (en) * | 1992-05-19 | 1999-08-16 | Xoma Corp | IMPROVED METHODS FOR THE PREPARATION OF BINDING PROTEINS TO ENDOTOXINS. |
US5420019A (en) * | 1993-02-02 | 1995-05-30 | Xoma Corporation | Stable bactericidal/permeability-increasing protein muteins |
WO1994017819A1 (en) * | 1993-02-02 | 1994-08-18 | Xoma Corporation | Pharmaceutical compositions containing bactericidal permeability increasing protein and a surfactant |
DE69410254T2 (en) * | 1993-03-12 | 1998-12-17 | Xoma Corp | TREATMENT OF MYCOBACTERIAL DISEASES THROUGH THE ADMINISTRATION OF BACRERIAL-KILLING, PLEASURE-INCREASING PROTEIN FRAGMENTS |
DK0690872T3 (en) * | 1993-03-12 | 1999-05-10 | Xoma Corp | Biologically active peptides from bacterial / permeability enhancing protein functional domains and uses thereof |
EP1129718A3 (en) * | 1993-03-12 | 2002-05-22 | XOMA Technology Ltd. | Therapeutic uses of bactericidal/permeability increasing protein products |
US5652332A (en) * | 1993-03-12 | 1997-07-29 | Xoma | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
US5348942A (en) * | 1993-03-12 | 1994-09-20 | Xoma Corporation | Therapeutic uses of bactericidal/permeability increasing protein products |
US5733872A (en) * | 1993-03-12 | 1998-03-31 | Xoma Corporation | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
AU6522794A (en) * | 1993-03-22 | 1994-10-11 | Incyte Pharmaceuticals, Inc. | Use of bactericidal/permeability increasing protein and lipopolysaccharide binding protein levels and ratios thereof in diagnosis |
EP0760849A1 (en) * | 1993-04-30 | 1997-03-12 | Incyte Pharmaceuticals, Inc. | Recombinant bpi-based and lbp-based proteins, nucleic acid molecules encoding same, methods of producing same, and uses thereof |
AU7175694A (en) * | 1993-06-17 | 1995-01-17 | Xoma Corporation | Lipopolysaccharide binding protein derivatives |
JPH09500269A (en) * | 1993-07-02 | 1997-01-14 | インサイト ファーマシューティカルズ,インク. | Glycosylated and non-glycosylated proteins with increased bactericidal / permeability and methods of making the same |
AU7330994A (en) * | 1993-07-14 | 1995-02-13 | Xoma Corporation | Method for potentiating bpi protein product bactericidal activity by administration of lbp protein products |
US5466580A (en) * | 1993-09-22 | 1995-11-14 | Xoma Corporation | Method for quantifying BPI in body fluids |
JPH09502987A (en) * | 1993-09-22 | 1997-03-25 | ゾーマ コーポレイション | Method of treating Gram-negative bacterial infections by administration of bactericidal / permeabilized (BPI) protein products and antibiotics |
CN1133634A (en) * | 1993-09-22 | 1996-10-16 | 爱克斯欧玛公司 | Method for quantifying BPI in body fluids |
ZA947783B (en) * | 1993-10-15 | 1996-05-05 | Xoma Corp | Method of treating depressed reticuloendothelial system function |
ATE219684T1 (en) * | 1994-01-14 | 2002-07-15 | Xoma Technology Ltd | ANTI-GRAM POSITIVE BACTERIAL METHODS AND AGENT |
ATE215379T1 (en) * | 1994-01-14 | 2002-04-15 | Xoma Technology Ltd | ANTIFUNGAL METHODS AND AGENTS |
US5484705A (en) * | 1994-01-24 | 1996-01-16 | Xoma Corporation | Method for quantifying lipopolysaccharide binding protein |
US5643875A (en) * | 1994-01-24 | 1997-07-01 | Friedmann; Nadav | Human therapeutic uses of bactericidal/permeability increasing (BPI) protein products |
US5578568A (en) * | 1994-04-22 | 1996-11-26 | Xoma Corporation | Method of treating conditions associated with intestinal ischemia/reperfusion |
US5532216A (en) * | 1994-06-24 | 1996-07-02 | Incyte Pharmaceuticals, Inc. | Neutralization of non-lipopolysaccharide compounds by bactericidal/permeability-increasing protein |
EP0824547B1 (en) * | 1994-09-15 | 2003-12-10 | XOMA Technology Ltd. | Anti-fungal peptides |
US5494896A (en) * | 1995-03-31 | 1996-02-27 | Xoma Corporation | Method of treating conditions associated with burn injuries |
JP2001520631A (en) * | 1995-07-20 | 2001-10-30 | ゾーマ コーポレイション | Antifungal peptide |
AU730307B2 (en) * | 1995-11-14 | 2001-03-01 | Xoma Corporation | Bactericidal permeability increasing protein (BPI) for treating conditions associated with corneal injury |
US5686414A (en) * | 1995-11-14 | 1997-11-11 | Xoma Corporation | Methods of treating conditions associated with corneal transplantation |
US5741779A (en) * | 1996-05-10 | 1998-04-21 | Xoma Corporation | Antithrombotic materials and methods |
PT914144E (en) * | 1996-05-10 | 2001-05-31 | Univ Texas | THERAPEUTIC UTILIZATIONS OF BIP PROTEIN PRODUCTS AGAINST HUMAN MENINGOCOCCEMIA |
US5746753A (en) * | 1996-05-13 | 1998-05-05 | Boston Scientific Corporation | Needle grasping apparatus |
WO1997044056A1 (en) * | 1996-05-23 | 1997-11-27 | Xoma Corporation | Therapeutic uses of bpi protein products in humans with hemorrhage due to trauma |
US5888973A (en) * | 1996-08-09 | 1999-03-30 | Xoma Corporation | Anti-chlamydial uses of BPI protein products |
-
1996
- 1996-08-09 US US08/694,843 patent/US5888973A/en not_active Expired - Fee Related
-
1997
- 1997-08-07 AT AT97936420T patent/ATE226442T1/en not_active IP Right Cessation
- 1997-08-07 EP EP97936420A patent/EP0918533B1/en not_active Expired - Lifetime
- 1997-08-07 AU AU39094/97A patent/AU741480B2/en not_active Ceased
- 1997-08-07 CN CN97198452A patent/CN1232401A/en active Pending
- 1997-08-07 WO PCT/US1997/013810 patent/WO1998006415A2/en active IP Right Grant
- 1997-08-07 DE DE69716605T patent/DE69716605T2/en not_active Expired - Fee Related
- 1997-08-07 CA CA002263181A patent/CA2263181C/en not_active Expired - Fee Related
- 1997-08-07 NZ NZ334041A patent/NZ334041A/en unknown
- 1997-08-07 JP JP10509836A patent/JP2001500117A/en active Pending
-
1999
- 1999-03-29 US US09/281,985 patent/US6162788A/en not_active Expired - Fee Related
-
2000
- 2000-10-30 US US09/699,625 patent/US6583116B1/en not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989001486A1 (en) * | 1987-08-11 | 1989-02-23 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
WO1995024209A1 (en) * | 1994-03-11 | 1995-09-14 | Xoma Corporation | Therapeutic uses of bactericidal/permeability-increasing protein dimer products |
WO1996001647A1 (en) * | 1994-07-11 | 1996-01-25 | Xoma Corporation | Anti-protozoan methods and materials |
WO1996021436A1 (en) * | 1995-01-13 | 1996-07-18 | Xoma Corporation | Improved therapeutic compositions comprising bactericidal/permeability-increasing (bpi) protein products |
Non-Patent Citations (2)
Title |
---|
L. LAMBERT ET AL.: "SUSCEPTIBILITY OF CHLAMYDIA TRACHOMATIS TO RECOMBINANT BACTERICIDAL/PERMEABILITY INCREASING PROTEIN (RBPI21).", ABSTRACTS OF THE 36TH INTERSCIENCE CONFERENCE ON ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 15 September 1996 (1996-09-15) - 18 September 1996 (1996-09-18), pages 141, XP002058449 * |
R.D. INMAN ET AL.: "COMPARATIVE MICROBICIDAL ACTIVITY OF SYNOVIAL FLUID ON ARTHRITOGENIC ORGANISMS.", CLIN. EXP. IMMUNOL., vol. 104, no. 1, April 1996 (1996-04-01), pages 80 - 85, XP002058450 * |
Also Published As
Publication number | Publication date |
---|---|
EP0918533A2 (en) | 1999-06-02 |
AU741480B2 (en) | 2001-11-29 |
DE69716605D1 (en) | 2002-11-28 |
JP2001500117A (en) | 2001-01-09 |
CA2263181A1 (en) | 1998-02-19 |
US5888973A (en) | 1999-03-30 |
WO1998006415A2 (en) | 1998-02-19 |
ATE226442T1 (en) | 2002-11-15 |
US6583116B1 (en) | 2003-06-24 |
DE69716605T2 (en) | 2003-06-26 |
US6162788A (en) | 2000-12-19 |
EP0918533B1 (en) | 2002-10-23 |
CA2263181C (en) | 2003-03-18 |
AU3909497A (en) | 1998-03-06 |
CN1232401A (en) | 1999-10-20 |
NZ334041A (en) | 2000-10-27 |
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