WO1998006415A3 - Anti-chlamydial methods and materials - Google Patents

Anti-chlamydial methods and materials Download PDF

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Publication number
WO1998006415A3
WO1998006415A3 PCT/US1997/013810 US9713810W WO9806415A3 WO 1998006415 A3 WO1998006415 A3 WO 1998006415A3 US 9713810 W US9713810 W US 9713810W WO 9806415 A3 WO9806415 A3 WO 9806415A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
chlamydial
materials
chlamydial infection
bpi
Prior art date
Application number
PCT/US1997/013810
Other languages
French (fr)
Other versions
WO1998006415A2 (en
Inventor
Lewis H Lambert Jr
Original Assignee
Xoma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xoma Corp filed Critical Xoma Corp
Priority to AT97936420T priority Critical patent/ATE226442T1/en
Priority to AU39094/97A priority patent/AU741480B2/en
Priority to JP10509836A priority patent/JP2001500117A/en
Priority to CA002263181A priority patent/CA2263181C/en
Priority to EP97936420A priority patent/EP0918533B1/en
Priority to NZ334041A priority patent/NZ334041A/en
Priority to DE69716605T priority patent/DE69716605T2/en
Publication of WO1998006415A2 publication Critical patent/WO1998006415A2/en
Publication of WO1998006415A3 publication Critical patent/WO1998006415A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1751Bactericidal/permeability-increasing protein [BPI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Abstract

The present invention relates to methods for treating chlamydial infection comprising administering to a subject suffering from a chlamydial infection a bactericidal/permeability-inducing (BPI) protein product.
PCT/US1997/013810 1996-08-09 1997-08-07 Anti-chlamydial methods and materials WO1998006415A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AT97936420T ATE226442T1 (en) 1996-08-09 1997-08-07 ANTI-CHLAMYDIA METHODS AND MEANS
AU39094/97A AU741480B2 (en) 1996-08-09 1997-08-07 Anti-chlamydial methods and materials
JP10509836A JP2001500117A (en) 1996-08-09 1997-08-07 Anti-Chlamydia methods and substances
CA002263181A CA2263181C (en) 1996-08-09 1997-08-07 Anti-chlamydial methods and materials
EP97936420A EP0918533B1 (en) 1996-08-09 1997-08-07 Anti-chlamydial methods and materials
NZ334041A NZ334041A (en) 1996-08-09 1997-08-07 Anti-chlamydial activity of BPI (bactericidal/permeability increasing proteins) protein products against chlamydia infected host cells
DE69716605T DE69716605T2 (en) 1996-08-09 1997-08-07 ANTI-CHLAMYDIA METHOD AND MEANS

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/694,843 US5888973A (en) 1996-08-09 1996-08-09 Anti-chlamydial uses of BPI protein products
US08/694,843 1996-08-09

Publications (2)

Publication Number Publication Date
WO1998006415A2 WO1998006415A2 (en) 1998-02-19
WO1998006415A3 true WO1998006415A3 (en) 1998-05-14

Family

ID=24790487

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/013810 WO1998006415A2 (en) 1996-08-09 1997-08-07 Anti-chlamydial methods and materials

Country Status (10)

Country Link
US (3) US5888973A (en)
EP (1) EP0918533B1 (en)
JP (1) JP2001500117A (en)
CN (1) CN1232401A (en)
AT (1) ATE226442T1 (en)
AU (1) AU741480B2 (en)
CA (1) CA2263181C (en)
DE (1) DE69716605T2 (en)
NZ (1) NZ334041A (en)
WO (1) WO1998006415A2 (en)

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US5198541A (en) * 1987-08-11 1993-03-30 New York University Dna encoding bactericidal/permeability-increasing proteins
US5888973A (en) * 1996-08-09 1999-03-30 Xoma Corporation Anti-chlamydial uses of BPI protein products
WO1998006435A2 (en) * 1996-08-14 1998-02-19 Vanderbilt University COMPOSITIONS OF ANTICHLAMYDIAL AGENTS FOR THE DIAGNOSIS AND MANAGEMENT OF INFECTION CAUSED BY $i(CHLAMYDIA)
US6482796B2 (en) 1996-11-01 2002-11-19 Xoma Corporation Therapeutic uses of N-terminal BPI protein products in ANCA-positive patients
US6884784B1 (en) * 1997-05-06 2005-04-26 Vanderbilt University Diagnosis and management of infection caused by chlamydia
US6093573A (en) * 1997-06-20 2000-07-25 Xoma Three-dimensional structure of bactericidal/permeability-increasing protein (BPI)
US6013631A (en) * 1998-06-19 2000-01-11 Xoma Corporation Bactericidal/permeability-increasing protein (BPI) deletion analogs
US6310073B1 (en) * 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
US6239113B1 (en) * 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
US7056893B2 (en) * 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
US6153584A (en) * 1999-04-01 2000-11-28 Levy; Ofer Therapeutic uses of BPI protein products in BPI-deficient humans
US7041644B2 (en) 1999-04-01 2006-05-09 Xoma Technology Therapeutic uses of BPI protein products in BPI-deficient humans
US20020173464A1 (en) * 2000-12-01 2002-11-21 King George L. Modulation of pericyte proliferation
AU2003239438A1 (en) * 2002-05-15 2003-12-02 University Of Washintgon Method of screening anti-bacterial agents for effectiveness in treating persistent intracellular infections
US20050014932A1 (en) * 2003-05-15 2005-01-20 Iogenetics, Llc Targeted biocides
US8703134B2 (en) 2003-05-15 2014-04-22 Iogenetics, Llc Targeted cryptosporidium biocides
US8394379B2 (en) * 2003-05-15 2013-03-12 Iogenetics, Llc Targeted cryptosporidium biocides
US20060046970A1 (en) * 2004-08-31 2006-03-02 Insite Vision Incorporated Topical otic compositions and methods of topical treatment of prevention of otic infections
WO2006113526A2 (en) * 2005-04-15 2006-10-26 The Regents Of The University Of California Prevention of chlamydia infection using a protective antibody
EP1741440A1 (en) 2005-07-08 2007-01-10 Mellitus S.L. Use of BPI protein for the treatment of disorders of the metabolism and cardiovascular disorders
GB201319620D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Immunosuppressive agents and their use in therapy
GB201319621D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Antimicrobial agents and their use in therapy
US10602795B2 (en) 2017-01-26 2020-03-31 Bell Sports, Inc. Helmet comprising a segmented shell

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WO1995024209A1 (en) * 1994-03-11 1995-09-14 Xoma Corporation Therapeutic uses of bactericidal/permeability-increasing protein dimer products
WO1996001647A1 (en) * 1994-07-11 1996-01-25 Xoma Corporation Anti-protozoan methods and materials
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US5576292A (en) * 1987-08-11 1996-11-19 New York University Biologically active bactericidal/permeability-increasing protein fragments
US5198541A (en) * 1987-08-11 1993-03-30 New York University Dna encoding bactericidal/permeability-increasing proteins
US5171739A (en) * 1989-02-14 1992-12-15 Incyte Pharmaceuticals, Inc. Treatment of endotoxin-associated shock and preventation thereof using a BPI protein
US5334584A (en) * 1989-02-14 1994-08-02 Incyte Pharamaceuticals, Inc. Recombinant, non-glycosylated bpi protein and uses thereof
US5089274A (en) * 1989-02-14 1992-02-18 Incyte Pharmaceuticals, Inc. Use of bactericidal/permeability increasing protein or biologically active analogs thereof to treat endotoxin-related disorders
US5234912A (en) * 1989-02-14 1993-08-10 Incyte Pharmaceuticals, Inc. Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof
US5308834A (en) * 1989-02-14 1994-05-03 Incyte Pharmaceuticals, Inc. Treatment of endotoxin-associated shock and prevention thereof using a BPI protein
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Also Published As

Publication number Publication date
EP0918533A2 (en) 1999-06-02
AU741480B2 (en) 2001-11-29
DE69716605D1 (en) 2002-11-28
JP2001500117A (en) 2001-01-09
CA2263181A1 (en) 1998-02-19
US5888973A (en) 1999-03-30
WO1998006415A2 (en) 1998-02-19
ATE226442T1 (en) 2002-11-15
US6583116B1 (en) 2003-06-24
DE69716605T2 (en) 2003-06-26
US6162788A (en) 2000-12-19
EP0918533B1 (en) 2002-10-23
CA2263181C (en) 2003-03-18
AU3909497A (en) 1998-03-06
CN1232401A (en) 1999-10-20
NZ334041A (en) 2000-10-27

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