WO1997046682A3 - Polynucleotides from human adult PBMC encoding secreted proteins - Google Patents

Polynucleotides from human adult PBMC encoding secreted proteins Download PDF

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Publication number
WO1997046682A3
WO1997046682A3 PCT/US1997/009865 US9709865W WO9746682A3 WO 1997046682 A3 WO1997046682 A3 WO 1997046682A3 US 9709865 W US9709865 W US 9709865W WO 9746682 A3 WO9746682 A3 WO 9746682A3
Authority
WO
WIPO (PCT)
Prior art keywords
secreted proteins
polynucleotides
encoding secreted
human adult
adult pbmc
Prior art date
Application number
PCT/US1997/009865
Other languages
French (fr)
Other versions
WO1997046682A2 (en
Inventor
Kenneth Jacobs
John M Mccoy
Lisa A Racie
Adward R Lavallie
David Merberg
Maurica Treacy
Cheryl Evans
Michael Bowman
Vikki Spaulding
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Priority to CA002257243A priority Critical patent/CA2257243A1/en
Priority to EP97932156A priority patent/EP0915971A2/en
Priority to AU35686/97A priority patent/AU3568697A/en
Priority to JP10500876A priority patent/JP2000515726A/en
Publication of WO1997046682A2 publication Critical patent/WO1997046682A2/en
Publication of WO1997046682A3 publication Critical patent/WO1997046682A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention provides a clone D 147-17 isolated from a human adult PBMC cDNA library comprising polynucleotides encoding secreted proteins using methods selective for cDNAs encoding secreted proteins.
PCT/US1997/009865 1996-06-07 1997-06-06 Polynucleotides from human adult pbmc encoding secreted proteins WO1997046682A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002257243A CA2257243A1 (en) 1996-06-07 1997-06-06 Polynucleotides from human adult pbmc encoding secreted proteins
EP97932156A EP0915971A2 (en) 1996-06-07 1997-06-06 Polynucleotides from human adult pbmc endocing secreted proteins
AU35686/97A AU3568697A (en) 1996-06-07 1997-06-06 Polynucleotides from human adult pbmc endocing secreted proteins
JP10500876A JP2000515726A (en) 1996-06-07 1997-06-06 Polynucleotide derived from adult PBMC encoding secreted protein

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65922496A 1996-06-07 1996-06-07
US08/659,224 1996-06-07
US08/867,677 1997-06-02

Publications (2)

Publication Number Publication Date
WO1997046682A2 WO1997046682A2 (en) 1997-12-11
WO1997046682A3 true WO1997046682A3 (en) 1998-03-12

Family

ID=24644568

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US1997/009878 WO1997046683A2 (en) 1996-06-07 1997-06-06 Polynucleotides encoding secreted proteins
PCT/US1997/009865 WO1997046682A2 (en) 1996-06-07 1997-06-06 Polynucleotides from human adult pbmc encoding secreted proteins

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US1997/009878 WO1997046683A2 (en) 1996-06-07 1997-06-06 Polynucleotides encoding secreted proteins

Country Status (5)

Country Link
EP (1) EP0910638A2 (en)
JP (2) JP2000515726A (en)
AU (2) AU3380497A (en)
CA (1) CA2256522A1 (en)
WO (2) WO1997046683A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7005509B1 (en) 1995-02-17 2006-02-28 Incyte Corporation Chemokine PANEC-1 polynucleotides and compositions and methods related thereto
US7265201B1 (en) 1995-06-23 2007-09-04 Millennium Pharmaceuticals, Inc. Human chemotactic cytokine
AU2451199A (en) * 1998-01-07 1999-07-26 Human Genome Sciences, Inc. 36 human secreted proteins
US6875741B2 (en) 1998-09-02 2005-04-05 Renuka Pillutla Insulin and IGF-1 receptor agonists and antagonists
US7173005B2 (en) 1998-09-02 2007-02-06 Antyra Inc. Insulin and IGF-1 receptor agonists and antagonists
AU2000239309A1 (en) * 2000-03-29 2001-10-08 Dgi Biotechnologies Llc Insulin and igf-1 receptor agonists and antagonists
CN111334469A (en) * 2020-03-27 2020-06-26 郑州鲲鹏健康科技有限公司 PBMC (peripheral blood mononuclear cell) in-vitro 3D (three-dimensional) methylcellulose agarose hydrogel culture medium and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
CALLARD R E ET AL: "AIMS OF THE BOOK", CYTOKINE FACTSBOOK, 1994, CALLARD R E;GEARING A J H, pages 2/3, 31 - 38, 64/65, 75/76, 97/98, 148 - 151, 252/253, XP002039160 *
JACOBS K ET AL: "A NOVEL METHOD FOR ISOLATING EUKARYOTIC CDNA CLONES ENCODING SECRETED PROTEINS", JOURNAL OF CELLULAR BIOCHEMISTRY - SUPPLEMENT, vol. 21A, 10 March 1995 (1995-03-10), pages 19, XP002027246 *
K. A. JACOBS ET AL: "A genetic selection for isolating cDNAs encoding secreted proteins", GENE., vol. 198, 1 October 1997 (1997-10-01), AMSTERDAM NL, pages 289 - 296, XP002045919 *
L. HILLIER ET AL: "The WashU-Merck EST project. ym65b04.r1 Homo sapiens cDNA clone 163759 5'", EMBL DATABASE ENTRY HS129166 ; ACCESSION NUMBER H14129, 11 July 1995 (1995-07-11), XP002046553 *
L. HILLIER ET AL: "The WashU-Merck EST project. zk50e05.s1 Soares pregnant uterus NbHPU Homo sapiens cDNA clone 486272 3'", EMBL DATABASE ENTRY HSA44020; ACCESSION NUMBER AA044020, 7 September 1996 (1996-09-07), XP002046554 *
M. YOKOYAMA-KOBAYASHI ET AL: "A signal sequence detection system using secreted protease activity as an indicator", GENE., vol. 163, 1995, AMSTERDAM NL, pages 193 - 196, XP002046435 *
TASHIRO K ET AL: "SIGNAL SEQUENCE TRAP: A CLONING STRATEGY FOR SECRETED PROTEINS AND TYPE I MEMBRANE PROTEINS", SCIENCE, vol. 261, 30 July 1993 (1993-07-30), pages 600 - 603, XP000673204 *

Also Published As

Publication number Publication date
CA2256522A1 (en) 1997-12-11
EP0910638A2 (en) 1999-04-28
AU3380497A (en) 1998-01-05
AU3568697A (en) 1998-01-05
WO1997046683A2 (en) 1997-12-11
WO1997046683A3 (en) 1998-05-07
WO1997046682A2 (en) 1997-12-11
JP2001501455A (en) 2001-02-06
JP2000515726A (en) 2000-11-28

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