WO1997040462A3 - Correlating polymorphic forms with multiple phenotypes - Google Patents

Correlating polymorphic forms with multiple phenotypes Download PDF

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Publication number
WO1997040462A3
WO1997040462A3 PCT/US1997/006457 US9706457W WO9740462A3 WO 1997040462 A3 WO1997040462 A3 WO 1997040462A3 US 9706457 W US9706457 W US 9706457W WO 9740462 A3 WO9740462 A3 WO 9740462A3
Authority
WO
WIPO (PCT)
Prior art keywords
polymorphic forms
correlating
phenotypes
multiple phenotypes
database
Prior art date
Application number
PCT/US1997/006457
Other languages
French (fr)
Other versions
WO1997040462A2 (en
Inventor
Stephen J Peroutka
Original Assignee
Spectra Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spectra Biomedical Inc filed Critical Spectra Biomedical Inc
Priority to JP9538193A priority Critical patent/JP2000508912A/en
Priority to EP97921244A priority patent/EP0897567A2/en
Priority to AU27341/97A priority patent/AU2734197A/en
Publication of WO1997040462A2 publication Critical patent/WO1997040462A2/en
Publication of WO1997040462A3 publication Critical patent/WO1997040462A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40—Population genetics; Linkage disequilibrium
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations

Abstract

This invention provides a database containing value sets indicating polymorphic forms and phenotypes for each member of a subject population, and methods of analyzing the database to determine the correlation between the polymorphic form at at least one genetic locus and at least two phenotypes.
PCT/US1997/006457 1996-04-19 1997-04-18 Correlating polymorphic forms with multiple phenotypes WO1997040462A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP9538193A JP2000508912A (en) 1996-04-19 1997-04-18 Correlating polymorphic forms with multiple phenotypes
EP97921244A EP0897567A2 (en) 1996-04-19 1997-04-18 Correlating polymorphic forms with multiple phenotypes
AU27341/97A AU2734197A (en) 1996-04-19 1997-04-18 Correlating polymorphic forms with multiple phenotypes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63651796A 1996-04-19 1996-04-19
US08/636,517 1996-04-19

Publications (2)

Publication Number Publication Date
WO1997040462A2 WO1997040462A2 (en) 1997-10-30
WO1997040462A3 true WO1997040462A3 (en) 1998-03-05

Family

ID=24552242

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/006457 WO1997040462A2 (en) 1996-04-19 1997-04-18 Correlating polymorphic forms with multiple phenotypes

Country Status (4)

Country Link
EP (1) EP0897567A2 (en)
JP (1) JP2000508912A (en)
AU (1) AU2734197A (en)
WO (1) WO1997040462A2 (en)

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US9249456B2 (en) 2004-03-26 2016-02-02 Agena Bioscience, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis
US9394565B2 (en) 2003-09-05 2016-07-19 Agena Bioscience, Inc. Allele-specific sequence variation analysis

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JP2002526091A (en) * 1998-09-19 2002-08-20 アストラゼネカ・アクチエボラーグ Polymorphisms in the human alpha4 integrin subunit gene suitable for diagnosis and treatment of integrin ligand-mediated diseases
EP1114183A1 (en) * 1998-09-19 2001-07-11 AstraZeneca AB Polymorphisms in the human beta1 integrin subunit gene, suitable for diagnosis and treatment of integrin ligand mediated diseases
GB9820338D0 (en) * 1998-09-19 1998-11-11 Zeneca Ltd Chemical compounds
EP1233364A3 (en) * 1999-06-25 2004-11-10 Genaissance Pharmaceuticals, Inc. Methods for obtaining and using haplotype data
US7058517B1 (en) 1999-06-25 2006-06-06 Genaissance Pharmaceuticals, Inc. Methods for obtaining and using haplotype data
KR20020064298A (en) * 1999-10-13 2002-08-07 시쿼넘, 인코포레이티드 Methods for generating databases and databases for identifying polymorphic genetic markers
GB0001005D0 (en) * 2000-01-18 2000-03-08 Zeneca Ltd Methods
GB0000995D0 (en) * 2000-01-18 2000-03-08 Zeneca Ltd Methods
GB0000992D0 (en) * 2000-01-18 2000-03-08 Astrazeneca Uk Ltd Methods
GB0002366D0 (en) * 2000-02-03 2000-03-22 Astrazeneca Uk Ltd Diagnostic method
EP1130122A3 (en) * 2000-02-17 2001-10-17 AstraZeneca AB Methods for the diagnosis of polymorphisms in the human EP1-R gene
US6931326B1 (en) 2000-06-26 2005-08-16 Genaissance Pharmaceuticals, Inc. Methods for obtaining and using haplotype data
JP3947103B2 (en) 2000-07-14 2007-07-18 エフ．ホフマン−ラ ロシュ アーゲー A method to detect a predisposition to hepatotoxicity
GB0021667D0 (en) * 2000-09-04 2000-10-18 Glaxo Group Ltd Genetic study
EP1741722A3 (en) * 2000-10-21 2007-03-14 AstraZeneca AB Polymorphisms in the human P2X7 gene
JP2002330787A (en) * 2000-10-21 2002-11-19 Astrazeneca Ab Chemical substance
CA2872499C (en) * 2001-05-25 2016-07-05 Hitachi, Ltd. Information processing system using nucleotide sequence related information
JP2003067389A (en) * 2001-06-29 2003-03-07 Dainakomu:Kk Method for genopolytypic-related analysis, and program therefor
FI20021031A (en) * 2001-12-28 2003-06-29 Pertti Laehteenmaeki Nutritional Machine
FI20012593A0 (en) * 2001-12-28 2001-12-28 Pertti Laehteenmaeki A method and system for providing a nutrition information service
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AUPS115502A0 (en) * 2002-03-18 2002-04-18 Diatech Pty Ltd Assessing data sets
EP1534862A4 (en) * 2002-08-07 2007-10-10 Exelixis Inc Modulators of rabggt and methods of use thereof
JP5479663B2 (en) 2002-12-20 2014-04-23 セレラ コーポレーション Genetic polymorphism associated with myocardial infarction, detection method and use thereof
US20040146870A1 (en) * 2003-01-27 2004-07-29 Guochun Liao Systems and methods for predicting specific genetic loci that affect phenotypic traits
AU2004265494A1 (en) * 2003-08-14 2005-02-24 Mars, Incorporated IgA allelic variants
JP5649263B2 (en) 2003-11-26 2015-01-07 セレラ コーポレーション Genetic polymorphisms associated with cardiovascular disorders and drug responses, methods for their detection and uses
EP2423327B1 (en) 2004-05-07 2014-01-08 Celera Corporation Genetic polymorphism associated with liver fibrosis methods of detection and uses thereof
EP2194144B1 (en) 2004-11-16 2015-01-07 Trustees of Boston University Anti-Dual Endothelin-1/Angiotensin II receptor (DEAR) antibody for inhibiting disease-associated or pathological angiogenesis.
CA2600794C (en) 2005-03-11 2014-08-12 Applera Corporation Genetic polymorphisms associated with coronary heart disease, methods of detection and uses thereof
US7799530B2 (en) 2005-09-23 2010-09-21 Celera Corporation Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
US7695911B2 (en) 2005-10-26 2010-04-13 Celera Corporation Genetic polymorphisms associated with Alzheimer's Disease, methods of detection and uses thereof
CA2915679C (en) 2006-10-20 2017-12-12 Celera Corporation Genetic polymorphisms associated with venous thrombosis, methods of detection and uses thereof
US8039212B2 (en) 2007-11-05 2011-10-18 Celera Corporation Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof
US20090221620A1 (en) 2008-02-20 2009-09-03 Celera Corporation Gentic polymorphisms associated with stroke, methods of detection and uses thereof
EP2733222A1 (en) 2008-07-09 2014-05-21 Celera Corporation Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof
PL2467140T3 (en) 2009-08-21 2017-04-28 Novartis Ag Lapatinib for treating cancer
US20110269735A1 (en) 2010-04-19 2011-11-03 Celera Corporation Genetic polymorphisms associated with statin response and cardiovascular diseases, methods of detection and uses thereof
AU2011258875B2 (en) 2010-05-25 2016-05-05 The Regents Of The University Of California Bambam: parallel comparative analysis of high-throughput sequencing data
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US9646134B2 (en) 2010-05-25 2017-05-09 The Regents Of The University Of California Bambam: parallel comparative analysis of high-throughput sequencing data
US20120108651A1 (en) 2010-11-02 2012-05-03 Leiden University Medical Center (LUMC) Acting on Behalf of Academic Hospital Leiden (AZL) Genetic polymorphisms associated with venous thrombosis and statin response, methods of detection and uses thereof
AU2013214254B2 (en) 2012-01-31 2016-04-21 Novartis Ag Method of treating cancer
WO2016016157A1 (en) 2014-07-30 2016-02-04 F. Hoffmann-La Roche Ag Genetic markers for predicting responsiveness to therapy with hdl-raising or hdl mimicking agent

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394565B2 (en) 2003-09-05 2016-07-19 Agena Bioscience, Inc. Allele-specific sequence variation analysis
US9249456B2 (en) 2004-03-26 2016-02-02 Agena Bioscience, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis

Also Published As

Publication number Publication date
WO1997040462A2 (en) 1997-10-30
AU2734197A (en) 1997-11-12
JP2000508912A (en) 2000-07-18
EP0897567A2 (en) 1999-02-24

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