WO1997040377A1 - Gerät zur höchstempfindlichen magnetischen detektion von analyten - Google Patents
Gerät zur höchstempfindlichen magnetischen detektion von analyten Download PDFInfo
- Publication number
- WO1997040377A1 WO1997040377A1 PCT/DE1997/000611 DE9700611W WO9740377A1 WO 1997040377 A1 WO1997040377 A1 WO 1997040377A1 DE 9700611 W DE9700611 W DE 9700611W WO 9740377 A1 WO9740377 A1 WO 9740377A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- detection
- measurement
- magnetic field
- sample
- magnetization
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S505/00—Superconductor technology: apparatus, material, process
- Y10S505/825—Apparatus per se, device per se, or process of making or operating same
- Y10S505/842—Measuring and testing
- Y10S505/843—Electrical
- Y10S505/845—Magnetometer
- Y10S505/846—Magnetometer using superconductive quantum interference device, i.e. squid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Measuring Magnetic Variables (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Inspection Of Paper Currency And Valuable Securities (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
Description
Claims
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR9708780-7A BR9708780A (pt) | 1996-04-18 | 1997-03-26 | "aparelho para detecção magnética da mais alta sensibilidade de analitos ". |
NZ331772A NZ331772A (en) | 1996-04-18 | 1997-03-26 | Device for highly sensitive magnetic detection of analytes with receptor ligand binding |
KR1019980708390A KR100305102B1 (ko) | 1996-04-18 | 1997-03-26 | 물질의고감도자기감지를위한기기장치 |
IL12606797A IL126067A (en) | 1996-04-18 | 1997-03-26 | Device for highly sensitive magnetic detection of analytes |
AU28854/97A AU718523B2 (en) | 1996-04-18 | 1997-03-26 | Apparatus for highest sensitivity magnetic detection of analytes |
CA002250087A CA2250087C (en) | 1996-04-18 | 1997-03-26 | Device for highly sensitive magnetic detection of analytes |
EP97922816A EP0898706B1 (de) | 1996-04-18 | 1997-03-26 | Gerät zur höchstempfindlichen magnetischen detektion von analyten |
DK97922816T DK0898706T3 (da) | 1996-04-18 | 1997-03-26 | Apparat til meget følsom magnetisk detektering af analytter |
DE29780349U DE29780349U1 (de) | 1996-04-18 | 1997-03-26 | Gerät zur höchstempfindlichen magnetischen Detektion von Analyten |
JP53756197A JP2001515585A (ja) | 1996-04-18 | 1997-03-26 | 分析物の最高感度磁気検出装置 |
DE59709508T DE59709508D1 (de) | 1996-04-18 | 1997-03-26 | Gerät zur höchstempfindlichen magnetischen detektion von analyten |
UA98116048A UA41476C2 (uk) | 1996-04-18 | 1997-03-26 | Пристрій для високочутливої магнітної детекції аналітів (варіанти) |
US09/147,093 US6123902A (en) | 1996-04-18 | 1997-03-26 | Device for highly sensitive magnetic detection of analytes |
SK1435-98A SK283627B6 (sk) | 1996-04-18 | 1997-03-26 | Zariadenie na čo najcitlivejšiu magnetickú detekciu analytov |
AT97922816T ATE234465T1 (de) | 1996-04-18 | 1997-03-26 | Gerät zur höchstempfindlichen magnetischen detektion von analyten |
PL97328792A PL183725B1 (pl) | 1996-04-18 | 1998-09-23 | Urządzenie do określania zawartości analitu w próbce, zwłaszcza biologicznej, za pomocą pola magnetycznego |
NO984856A NO984856L (no) | 1996-04-18 | 1998-10-16 | Innretning for kvalitativ og/eller kvantitativ analyse av analytter, basert pÕ f°lsom magnetisk deteksjon |
HK99104387A HK1019249A1 (en) | 1996-04-18 | 1999-10-07 | Device for highly sensitive magnetic detection of analytes |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19615254.2 | 1996-04-18 | ||
DE19615254A DE19615254C2 (de) | 1996-04-18 | 1996-04-18 | Gerät zur höchstempfindlichen magnetischen Detektion von Analyten |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997040377A1 true WO1997040377A1 (de) | 1997-10-30 |
Family
ID=7791594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE1997/000611 WO1997040377A1 (de) | 1996-04-18 | 1997-03-26 | Gerät zur höchstempfindlichen magnetischen detektion von analyten |
Country Status (26)
Country | Link |
---|---|
US (1) | US6123902A (de) |
EP (1) | EP0898706B1 (de) |
JP (1) | JP2001515585A (de) |
KR (1) | KR100305102B1 (de) |
CN (1) | CN1105917C (de) |
AT (1) | ATE234465T1 (de) |
AU (1) | AU718523B2 (de) |
BR (1) | BR9708780A (de) |
CA (1) | CA2250087C (de) |
CZ (1) | CZ293853B6 (de) |
DE (3) | DE19615254C2 (de) |
DK (1) | DK0898706T3 (de) |
ES (1) | ES2192269T3 (de) |
GE (1) | GEP20012591B (de) |
HK (1) | HK1019249A1 (de) |
HU (1) | HUP9901377A3 (de) |
IL (1) | IL126067A (de) |
NO (1) | NO984856L (de) |
NZ (1) | NZ331772A (de) |
PL (1) | PL183725B1 (de) |
PT (1) | PT898706E (de) |
RU (1) | RU2217751C2 (de) |
SK (1) | SK283627B6 (de) |
TW (1) | TW356519B (de) |
UA (1) | UA41476C2 (de) |
WO (1) | WO1997040377A1 (de) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1240509A1 (de) * | 1999-11-30 | 2002-09-18 | Quantum Design, Inc. | Verfahren und vorrichtung zur messung der anhaüfung von magnetischen teilchen |
US7993581B2 (en) | 2004-03-11 | 2011-08-09 | Hitachi, Ltd. | Immunoassay system and immunoassay method |
US9488648B2 (en) | 2010-10-22 | 2016-11-08 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
US9702852B2 (en) | 2010-10-22 | 2017-07-11 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
US11519016B2 (en) | 2016-01-21 | 2022-12-06 | T2 Biosystems, Inc. | NMR methods and systems for the rapid detection of bacteria |
Families Citing this family (33)
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DE19730497C2 (de) * | 1997-07-16 | 2000-02-10 | Heermann Klaus Hinrich | Verfahren zum Waschen, zur Separierung und Konzentrierung von Biomolekülen unter Verwendung eines Magnetstifts |
FI102906B1 (fi) * | 1998-02-23 | 1999-03-15 | Bio Nobile Oy | Menetelmä ja väline aineen siirtämiseksi |
US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8346337B2 (en) | 1998-04-30 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
US8465425B2 (en) | 1998-04-30 | 2013-06-18 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US6949816B2 (en) * | 2003-04-21 | 2005-09-27 | Motorola, Inc. | Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same |
US8974386B2 (en) | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8480580B2 (en) | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
AU4102000A (en) * | 1999-02-17 | 2000-09-04 | Kilian Hennes | Method for representing biologically activated inductance-altering particles anddevice for carrying out the method |
JP4171139B2 (ja) * | 1999-07-21 | 2008-10-22 | 住友電気工業株式会社 | 磁性体標識による免疫検査方法とその装置 |
GB2362588A (en) * | 2000-05-23 | 2001-11-28 | Alistair Forrest | Air freshening device |
US6420868B1 (en) * | 2000-06-16 | 2002-07-16 | Honeywell International Inc. | Read-out electronics for DC squid magnetic measurements |
US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
FI113297B (fi) * | 2001-06-19 | 2004-03-31 | Magnasense Oy | Menetelmä ja laitteisto analyyttien kvalitatiiviseksi ja kvantitatiiviseksi osoittamiseksi |
DE10210072B4 (de) * | 2002-03-08 | 2005-11-03 | Bundesrepublik Deutschland, vertr. d. d. Bundesministerium für Wirtschaft und Arbeit, dieses vertr. d. d. Präsidenten der Physikalisch-Technischen Bundesanstalt | Magnetometer |
US6724188B2 (en) * | 2002-03-29 | 2004-04-20 | Wavbank, Inc. | Apparatus and method for measuring molecular electromagnetic signals with a squid device and stochastic resonance to measure low-threshold signals |
EP1541083A3 (de) * | 2003-12-09 | 2006-03-01 | Olympus Corporation | Magnetflüssigkeitsdetektionsgerät |
JP4758713B2 (ja) * | 2005-08-30 | 2011-08-31 | 旭化成株式会社 | 磁気センサを用いた測定装置及び測定方法 |
US8034634B2 (en) * | 2005-11-16 | 2011-10-11 | Rex Chih-Yih Hong | Ultra-sensitive magnetoreduction measurement system and ultra-sensitive, wash-free assay using the same |
JP4676361B2 (ja) * | 2006-03-09 | 2011-04-27 | 株式会社日立製作所 | 磁気的免疫検査装置 |
JP4823726B2 (ja) * | 2006-03-17 | 2011-11-24 | 国立大学法人豊橋技術科学大学 | 生体高分子検出方法およびその検出装置 |
JP4837410B2 (ja) * | 2006-03-22 | 2011-12-14 | 富士フイルム株式会社 | 標的化合物の検出方法 |
DE102006061041B4 (de) * | 2006-12-22 | 2010-05-12 | Mesutronic Gerätebau GmbH | Einrichtung zur Überwachung eines Produktstromes auf störende Einschlüsse |
JP5326138B2 (ja) * | 2009-03-31 | 2013-10-30 | 国立大学法人豊橋技術科学大学 | 粉体材料中の磁性異物の検査装置およびその検査方法 |
JP5560334B2 (ja) * | 2010-07-21 | 2014-07-23 | 株式会社日立製作所 | 磁場計測装置 |
KR101039912B1 (ko) * | 2010-08-16 | 2011-06-09 | 강학성 | 매트릭스 구조의 위치판별이 가능한 미세 스틸볼 감지장치 |
JP6414498B2 (ja) * | 2015-03-27 | 2018-10-31 | 愛知製鋼株式会社 | 差動型磁気センサ |
CN108508390B (zh) * | 2018-05-28 | 2020-05-08 | 哈尔滨工业大学 | 矢量磁传感器的标定方法及其简便标定方法 |
SE1950159A1 (en) * | 2019-02-11 | 2020-08-12 | Alexei Kalaboukhov | Measurement system for magnetic samples |
CN111073948A (zh) * | 2019-07-04 | 2020-04-28 | 山东百多安医疗器械有限公司 | 一种非接触式细胞弱磁的测定方法 |
CN215641015U (zh) * | 2021-04-27 | 2022-01-25 | 杭州电子科技大学 | 磁传感涡流无损探伤检测系统 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4913883A (en) * | 1987-07-20 | 1990-04-03 | Hitachi, Ltd. | Particle agglutination immunoassay apparatus |
JPH03220442A (ja) * | 1990-01-25 | 1991-09-27 | Tdk Corp | 磁気微粒子の粒度測定方法 |
US5486457A (en) * | 1993-08-25 | 1996-01-23 | Children's Medical Center Corporation | Method and system for measurement of mechanical properties of molecules and cells |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6390765A (ja) * | 1986-10-03 | 1988-04-21 | Nippon Telegr & Teleph Corp <Ntt> | Squid免疫測定法 |
US5408178A (en) * | 1991-05-17 | 1995-04-18 | Vanderbilt University | Apparatus and method for imaging the structure of diamagnetic and paramagnetic objects |
JP3081902B2 (ja) * | 1991-11-07 | 2000-08-28 | 工業技術院長 | 磁場検出回路 |
US5329165A (en) * | 1992-05-26 | 1994-07-12 | Midwest Superconductivity, Inc. | Selectively switchable superconducting electromagnetic shield |
JP3204542B2 (ja) * | 1992-07-24 | 2001-09-04 | 株式会社東芝 | 磁場源測定装置 |
US5532592A (en) * | 1993-02-02 | 1996-07-02 | Conductus, Inc. | Squid control apparatus with non-cryogenic flux-locked loop disposed in close proximity to the squid |
DE19503664C2 (de) * | 1995-01-27 | 1998-04-02 | Schering Ag | Magnetorelaxometrische Detektion von Analyten |
DE19508772C2 (de) * | 1995-03-01 | 1998-01-29 | Schering Ag | Verfahren und Verbindungen zur Detektion von Analyten mittels Remanenzmessung und deren Verwendung |
JPH0984777A (ja) * | 1995-09-25 | 1997-03-31 | Toshiba Corp | 生体磁場計測装置 |
-
1996
- 1996-04-18 DE DE19615254A patent/DE19615254C2/de not_active Expired - Fee Related
-
1997
- 1997-03-26 CN CN97193888A patent/CN1105917C/zh not_active Expired - Fee Related
- 1997-03-26 AU AU28854/97A patent/AU718523B2/en not_active Ceased
- 1997-03-26 ES ES97922816T patent/ES2192269T3/es not_active Expired - Lifetime
- 1997-03-26 UA UA98116048A patent/UA41476C2/uk unknown
- 1997-03-26 DE DE29780349U patent/DE29780349U1/de not_active Expired - Lifetime
- 1997-03-26 BR BR9708780-7A patent/BR9708780A/pt not_active IP Right Cessation
- 1997-03-26 JP JP53756197A patent/JP2001515585A/ja not_active Ceased
- 1997-03-26 AT AT97922816T patent/ATE234465T1/de not_active IP Right Cessation
- 1997-03-26 PT PT97922816T patent/PT898706E/pt unknown
- 1997-03-26 EP EP97922816A patent/EP0898706B1/de not_active Expired - Lifetime
- 1997-03-26 SK SK1435-98A patent/SK283627B6/sk unknown
- 1997-03-26 CA CA002250087A patent/CA2250087C/en not_active Expired - Fee Related
- 1997-03-26 NZ NZ331772A patent/NZ331772A/xx unknown
- 1997-03-26 DK DK97922816T patent/DK0898706T3/da active
- 1997-03-26 GE GEAP19974573A patent/GEP20012591B/en unknown
- 1997-03-26 IL IL12606797A patent/IL126067A/xx not_active IP Right Cessation
- 1997-03-26 US US09/147,093 patent/US6123902A/en not_active Expired - Lifetime
- 1997-03-26 RU RU98120854/14A patent/RU2217751C2/ru not_active IP Right Cessation
- 1997-03-26 WO PCT/DE1997/000611 patent/WO1997040377A1/de active IP Right Grant
- 1997-03-26 KR KR1019980708390A patent/KR100305102B1/ko not_active IP Right Cessation
- 1997-03-26 HU HU9901377A patent/HUP9901377A3/hu unknown
- 1997-03-26 DE DE59709508T patent/DE59709508D1/de not_active Expired - Lifetime
- 1997-03-26 CZ CZ19983338A patent/CZ293853B6/cs not_active IP Right Cessation
- 1997-04-10 TW TW086104580A patent/TW356519B/zh active
-
1998
- 1998-09-23 PL PL97328792A patent/PL183725B1/pl not_active IP Right Cessation
- 1998-10-16 NO NO984856A patent/NO984856L/no not_active Application Discontinuation
-
1999
- 1999-10-07 HK HK99104387A patent/HK1019249A1/xx not_active IP Right Cessation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4913883A (en) * | 1987-07-20 | 1990-04-03 | Hitachi, Ltd. | Particle agglutination immunoassay apparatus |
JPH03220442A (ja) * | 1990-01-25 | 1991-09-27 | Tdk Corp | 磁気微粒子の粒度測定方法 |
US5486457A (en) * | 1993-08-25 | 1996-01-23 | Children's Medical Center Corporation | Method and system for measurement of mechanical properties of molecules and cells |
Non-Patent Citations (1)
Title |
---|
PATENT ABSTRACTS OF JAPAN vol. 15, no. 507 (P - 1291) 20 December 1991 (1991-12-20) * |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6597176B2 (en) * | 1997-11-21 | 2003-07-22 | Quantum Design, Inc. | Method and apparatus for making measurements of patterns of magnetic particles in lateral flow membranes and microfluidic systems |
EP1240509A1 (de) * | 1999-11-30 | 2002-09-18 | Quantum Design, Inc. | Verfahren und vorrichtung zur messung der anhaüfung von magnetischen teilchen |
EP1240509A4 (de) * | 1999-11-30 | 2003-03-19 | Quantum Design Inc | Verfahren und vorrichtung zur messung der anhaüfung von magnetischen teilchen |
US7993581B2 (en) | 2004-03-11 | 2011-08-09 | Hitachi, Ltd. | Immunoassay system and immunoassay method |
US9488648B2 (en) | 2010-10-22 | 2016-11-08 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
US9702852B2 (en) | 2010-10-22 | 2017-07-11 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
US9714940B2 (en) | 2010-10-22 | 2017-07-25 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
US11519016B2 (en) | 2016-01-21 | 2022-12-06 | T2 Biosystems, Inc. | NMR methods and systems for the rapid detection of bacteria |
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