WO1997039050A1 - Sustained release heterodisperse hydrogel systems - amorphous drugs - Google Patents
Sustained release heterodisperse hydrogel systems - amorphous drugs Download PDFInfo
- Publication number
- WO1997039050A1 WO1997039050A1 PCT/US1997/006816 US9706816W WO9739050A1 WO 1997039050 A1 WO1997039050 A1 WO 1997039050A1 US 9706816 W US9706816 W US 9706816W WO 9739050 A1 WO9739050 A1 WO 9739050A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sustained release
- dosage form
- ofthe
- medicament
- solid dosage
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL12659597A IL126595A (en) | 1996-04-18 | 1997-04-18 | Sustained release solid dosage form comprising heterodisperse hydrogel drugs and process for preparation thereof |
EP97918790A EP0912627A4 (en) | 1996-04-18 | 1997-04-18 | Sustained release heterodisperse hydrogel systems - amorphous drugs |
IL14364297A IL143642A0 (en) | 1996-04-18 | 1997-04-18 | Sustained release heterodisperse hydrogel systems-amorphous drugs |
JP9537444A JPH11507958A (en) | 1996-04-18 | 1997-04-18 | Sustained release heterodisperse hydrogel system-amorphous drug |
CA002251816A CA2251816C (en) | 1996-04-18 | 1997-04-18 | Sustained release heterodisperse hydrogel systems - amorphous drugs |
AU26805/97A AU739114B2 (en) | 1996-04-18 | 1997-04-18 | Sustained release heterodisperse hydrogel systems - amorphous drugs |
NZ332299A NZ332299A (en) | 1996-04-18 | 1997-04-18 | Oral sustained release containing a hydrophilic and hydrophobic layer especially for medicaments containing nifedipine |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/634,295 US5773025A (en) | 1993-09-09 | 1996-04-18 | Sustained release heterodisperse hydrogel systems--amorphous drugs |
US08/634,295 | 1996-04-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997039050A1 true WO1997039050A1 (en) | 1997-10-23 |
Family
ID=24543216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/006816 WO1997039050A1 (en) | 1996-04-18 | 1997-04-18 | Sustained release heterodisperse hydrogel systems - amorphous drugs |
Country Status (9)
Country | Link |
---|---|
US (5) | US5773025A (en) |
EP (1) | EP0912627A4 (en) |
JP (1) | JPH11507958A (en) |
KR (1) | KR100384215B1 (en) |
AU (1) | AU739114B2 (en) |
CA (1) | CA2251816C (en) |
IL (1) | IL126595A (en) |
NZ (1) | NZ332299A (en) |
WO (1) | WO1997039050A1 (en) |
Cited By (12)
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WO1999021535A1 (en) * | 1997-10-25 | 1999-05-06 | Bayer Aktiengesellschaft | Osmotic medicament releasing system |
JP2000229888A (en) * | 1999-02-10 | 2000-08-22 | Pfizer Prod Inc | Matrix control release device |
WO2001005376A1 (en) * | 1999-07-20 | 2001-01-25 | Astrazeneca Ab | New pharmaceutical formulation |
GB2355194A (en) * | 1999-08-31 | 2001-04-18 | Bradford Particle Design Plc | Stable amorphous active component containing composition |
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GB2381453A (en) * | 1999-08-31 | 2003-05-07 | Bradford Particle Design Ltd | Active/polymer coformulations |
WO2004037290A1 (en) * | 2002-10-23 | 2004-05-06 | Hanmi Pharm. Co., Ltd. | Sustained release composition for oral administration of drugs |
EP1549296A1 (en) * | 2002-08-02 | 2005-07-06 | Penwest Pharmaceuticals Co. | Sustained release formulations of metformin |
US7507823B2 (en) | 2004-05-06 | 2009-03-24 | Bristol-Myers Squibb Company | Process of making aripiprazole particles |
CN101103964B (en) * | 2006-07-14 | 2010-09-29 | 海南盛科生命科学研究院 | Sustained-release preparation containing felodipine and preparation method thereof |
WO2013133448A1 (en) * | 2012-03-06 | 2013-09-12 | Otsuka Pharmaceutical Co., Ltd. | Sustained release oral solid preparation |
US9820982B2 (en) | 2001-07-06 | 2017-11-21 | Endo Pharmaceuticals Inc. | Oxymorphone controlled release formulations |
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US5773025A (en) * | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
US5455046A (en) * | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
AU2068797A (en) * | 1996-01-29 | 1997-08-20 | Edward Mendell Co. Inc. | Sustained release excipient |
CA2231195C (en) | 1996-07-08 | 2003-01-21 | Edward Mendell Co., Inc. | Sustained release matrix for high-dose insoluble drugs |
WO1998012274A1 (en) * | 1996-09-23 | 1998-03-26 | Chandrashekar Pathak | Methods and devices for preparing protein concentrates |
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- 1997-04-18 CA CA002251816A patent/CA2251816C/en not_active Expired - Fee Related
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WO1999021535A1 (en) * | 1997-10-25 | 1999-05-06 | Bayer Aktiengesellschaft | Osmotic medicament releasing system |
JP2005320354A (en) * | 1999-02-10 | 2005-11-17 | Pfizer Prod Inc | Matrix control release device |
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US7507823B2 (en) | 2004-05-06 | 2009-03-24 | Bristol-Myers Squibb Company | Process of making aripiprazole particles |
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WO2013133448A1 (en) * | 2012-03-06 | 2013-09-12 | Otsuka Pharmaceutical Co., Ltd. | Sustained release oral solid preparation |
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Also Published As
Publication number | Publication date |
---|---|
EP0912627A4 (en) | 2006-04-12 |
IL126595A0 (en) | 1999-08-17 |
EP0912627A1 (en) | 1999-05-06 |
CA2251816A1 (en) | 1997-10-23 |
KR20000005554A (en) | 2000-01-25 |
US5773025A (en) | 1998-06-30 |
US6048548A (en) | 2000-04-11 |
US6709677B2 (en) | 2004-03-23 |
JPH11507958A (en) | 1999-07-13 |
CA2251816C (en) | 2004-07-06 |
AU739114B2 (en) | 2001-10-04 |
AU2680597A (en) | 1997-11-07 |
NZ332299A (en) | 2001-01-26 |
KR100384215B1 (en) | 2003-08-30 |
US6245356B1 (en) | 2001-06-12 |
US20010046516A1 (en) | 2001-11-29 |
US20040241233A1 (en) | 2004-12-02 |
IL126595A (en) | 2001-12-23 |
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