WO1997029802A3 - Improved implantable microstimulator and systems employing the same - Google Patents

Improved implantable microstimulator and systems employing the same Download PDF

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Publication number
WO1997029802A3
WO1997029802A3 PCT/US1997/002576 US9702576W WO9729802A3 WO 1997029802 A3 WO1997029802 A3 WO 1997029802A3 US 9702576 W US9702576 W US 9702576W WO 9729802 A3 WO9729802 A3 WO 9729802A3
Authority
WO
WIPO (PCT)
Prior art keywords
microstimulators
microstimulator
control means
systems employing
chemical agents
Prior art date
Application number
PCT/US1997/002576
Other languages
French (fr)
Other versions
WO1997029802A2 (en
Inventor
Frances J R Richmond
Gerald E Loeb
Original Assignee
Advanced Bionics Corp
Frances J R Richmond
Gerald E Loeb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Bionics Corp, Frances J R Richmond, Gerald E Loeb filed Critical Advanced Bionics Corp
Priority to US09/077,662 priority Critical patent/US6051017A/en
Publication of WO1997029802A2 publication Critical patent/WO1997029802A2/en
Publication of WO1997029802A3 publication Critical patent/WO1997029802A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36003—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of motor muscles, e.g. for walking assistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37205—Microstimulators, e.g. implantable through a cannula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A61N1/37235—Aspects of the external programmer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A61N1/3756—Casings with electrodes thereon, e.g. leadless stimulators

Abstract

Improved implantable microstimulators covered with a biocompatible polymeric coating in order to provide increased strength to the capsule thereof and to capture fragments of the microstimulator should it become mechanically disrupted and to make the microstimulator safer and easier to handle are provided here. The coating may include one or more diffusible chemical agents that are released in a controlled manner into the surrounding tissue. The chemical agents, such as trophic factors, antibiotics, hormones, neurotransmitters and other pharmaceutical substances, are selected to produce desired physiological effects, to aid, support or to supplement the effects of the electrical stimulation. Further, provided herein are systems employing the improved microstimulators to prevent and/or treat various disorders associated with prolonged inactivity, confinement or immobilization of one or more muscles. Such disorders include pressure ulcers, venous emboli, autonomic dysreflexia, sensorimotor spasticity and muscle atrophy. These systems include external control means for controlling the operation of the microstimulators, said control means having memory means for programming preferred stimulation patterns for later activation by the patient or caregiver.
PCT/US1997/002576 1996-02-20 1997-02-19 Improved implantable microstimulator and systems employing the same WO1997029802A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US09/077,662 US6051017A (en) 1996-02-20 1997-02-19 Implantable microstimulator and systems employing the same

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US1187096P 1996-02-20 1996-02-20
US1186996P 1996-02-20 1996-02-20
US1201996P 1996-02-20 1996-02-20
US1186896P 1996-02-20 1996-02-20
US60/011,868 1996-02-20
US60/011,869 1996-02-20
US60/012,019 1996-02-20
US60/011,870 1996-02-20

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US09/490,922 Division US6214032B1 (en) 1996-02-20 2000-01-25 System for implanting a microstimulator
US09/490,919 Division US6185455B1 (en) 1996-02-20 2000-01-25 Method of reducing the incidence of medical complications using implantable microstimulators

Publications (2)

Publication Number Publication Date
WO1997029802A2 WO1997029802A2 (en) 1997-08-21
WO1997029802A3 true WO1997029802A3 (en) 1997-11-13

Family

ID=27486112

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/002576 WO1997029802A2 (en) 1996-02-20 1997-02-19 Improved implantable microstimulator and systems employing the same

Country Status (2)

Country Link
US (5) US6051017A (en)
WO (1) WO1997029802A2 (en)

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US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same

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US6181965B1 (en) 2001-01-30
US6214032B1 (en) 2001-04-10
WO1997029802A2 (en) 1997-08-21
US6175764B1 (en) 2001-01-16
US6051017A (en) 2000-04-18

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