WO1997024528A3 - Multichannel microdosing apparatus - Google Patents

Multichannel microdosing apparatus Download PDF

Info

Publication number
WO1997024528A3
WO1997024528A3 PCT/IL1996/000197 IL9600197W WO9724528A3 WO 1997024528 A3 WO1997024528 A3 WO 1997024528A3 IL 9600197 W IL9600197 W IL 9600197W WO 9724528 A3 WO9724528 A3 WO 9724528A3
Authority
WO
WIPO (PCT)
Prior art keywords
electrosensitive
members
channels
chamber
pumping
Prior art date
Application number
PCT/IL1996/000197
Other languages
French (fr)
Other versions
WO1997024528A2 (en
Inventor
Refael Bronstein
Ilan Fono
Mark Korenfeld
Original Assignee
Micro Infusion Ltd
Refael Bronstein
Ilan Fono
Mark Korenfeld
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micro Infusion Ltd, Refael Bronstein, Ilan Fono, Mark Korenfeld filed Critical Micro Infusion Ltd
Priority to IL12514096A priority Critical patent/IL125140A0/en
Priority to EP96941805A priority patent/EP0870110A2/en
Priority to AU11080/97A priority patent/AU1108097A/en
Publication of WO1997024528A2 publication Critical patent/WO1997024528A2/en
Publication of WO1997024528A3 publication Critical patent/WO1997024528A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1407—Infusion of two or more substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/141—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor with capillaries for restricting fluid flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B11/00—Equalisation of pulses, e.g. by use of air vessels; Counteracting cavitation
    • F04B11/0008—Equalisation of pulses, e.g. by use of air vessels; Counteracting cavitation using accumulators
    • F04B11/0033—Equalisation of pulses, e.g. by use of air vessels; Counteracting cavitation using accumulators with a mechanical spring
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/006—Micropumps
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/04—Pumps having electric drive
    • F04B43/043—Micropumps
    • F04B43/046—Micropumps with piezoelectric drive
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
    • F04B53/10—Valves; Arrangement of valves
    • F04B53/1002—Ball valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
    • F04B53/10—Valves; Arrangement of valves
    • F04B53/1037—Flap valves
    • F04B53/1047—Flap valves the valve being formed by one or more flexible elements
    • F04B53/105—Flap valves the valve being formed by one or more flexible elements one flexible element oscillating around a fixed point
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0272—Electro-active or magneto-active materials
    • A61M2205/0294—Piezoelectric materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers

Abstract

A pumping apparatus has a body portion with a chamber and channels (112) for receiving fluid that has entered the chamber through an opening (104) in the body portion. The chamber is covered by a membrane and the channels terminate in orifices (122), through which fluid exits the pump. Electrosensitive members (114), movable in response to electric signals, are positioned on portions of the membrane corresponding to the respective channels, within the pump body and the respective orifices. A control mechanism controls pumping of this apparatus by sending electrical signals to the electrosensitive members, that force fluid through the respective channels and out the respective orifice for delivery to the desired site. The control mechanism permits movement of at least one of the electrosensitive members independent of the other electrosensitive members, as well as concurrent and simultaneous movement of the electrosensitive members, depending upon the pumping mode desired.
PCT/IL1996/000197 1995-12-31 1996-12-31 Multichannel microdosing apparatus WO1997024528A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IL12514096A IL125140A0 (en) 1995-12-31 1996-12-31 Multichannel microdosing apparatus
EP96941805A EP0870110A2 (en) 1995-12-31 1996-12-31 Multichannel microdosing apparatus
AU11080/97A AU1108097A (en) 1995-12-31 1996-12-31 Multichannel microdosing apparatus

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL116628 1995-12-31
IL11662895A IL116628A0 (en) 1995-12-31 1995-12-31 A miniature multichannel piezoelectric pumping apparatus and methods of microdosing infusion introduction and inhalation

Publications (2)

Publication Number Publication Date
WO1997024528A2 WO1997024528A2 (en) 1997-07-10
WO1997024528A3 true WO1997024528A3 (en) 1997-10-30

Family

ID=11068381

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL1996/000197 WO1997024528A2 (en) 1995-12-31 1996-12-31 Multichannel microdosing apparatus

Country Status (4)

Country Link
EP (1) EP0870110A2 (en)
AU (1) AU1108097A (en)
IL (2) IL116628A0 (en)
WO (1) WO1997024528A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19737173B4 (en) * 1997-08-26 2007-04-05 Eppendorf Ag micro-dosing system
WO1999038621A1 (en) * 1998-01-28 1999-08-05 Danmist Aps Method of piezoelectrically atomising and pumping fluids and piezoelectric fluid atomising and pumping device
FR2794039B1 (en) 1999-05-27 2002-05-03 Osmooze Sa DEVICE FOR FORMING, MOVING AND DIFFUSING SMALL CALIBRATED QUANTITIES OF LIQUIDS
US6913933B2 (en) 2001-12-03 2005-07-05 Ortho-Clinical Diagnostics, Inc. Fluid dispensing algorithm for a variable speed pump driven metering system
NL1025624C2 (en) * 2004-03-03 2005-09-07 Solvist Flow restriction device for use in drug metering device, has opening having specific diameter, formed in plastic baffle which is formed integrally with conduit
EP1757807A1 (en) * 2005-08-24 2007-02-28 Mario Voland Micrometering system
EP2101060B1 (en) 2008-03-12 2011-09-21 Korea Institute Of Machinery & Materials Ultrasonic piezoelectric pump
WO2009150594A1 (en) * 2008-06-11 2009-12-17 Koninklijke Philips Electronics N.V. Micro-jet injection device for local submucosal drug application
WO2012126011A1 (en) * 2011-03-17 2012-09-20 K&Y Corporation Micro-infusion system
JP5286476B2 (en) 2011-12-08 2013-09-11 株式会社メトラン Pump unit, breathing assistance device
US20140276054A1 (en) * 2013-03-15 2014-09-18 Volcano Corporation Piezoelectric-Actuated Fluid-Delivery Devices and Associated Systems and Methods
FR3026646B1 (en) * 2014-10-06 2019-11-01 La Diffusion Technique Francaise FIXED TAMIS NEBULIZATION DEVICE
CN109890447B (en) 2016-09-15 2022-05-17 索芙特海尔公司 Valve, in particular for a device for administering a liquid drug, and corresponding device for administering a liquid drug
US10625254B2 (en) 2017-11-22 2020-04-21 Brand Gmbh + Co Kg Method for controlling a pipetting device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3325155A (en) * 1962-05-07 1967-06-13 Equipment Des Ind Chimiques S Valve tray apparatus
US4558995A (en) * 1983-04-25 1985-12-17 Ricoh Company, Ltd. Pump for supplying head of ink jet printer with ink under pressure
JPH02140475A (en) * 1988-11-21 1990-05-30 Seiko Epson Corp Piezoelectric micropump
US5192197A (en) * 1991-11-27 1993-03-09 Rockwell International Corporation Piezoelectric pump
US5611676A (en) * 1994-07-27 1997-03-18 Aisin Seiki Kabushiki Kaisha Micropump

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1530662A (en) 1976-03-01 1978-11-01 Mullard Ltd Peristaltic pump
GB8701731D0 (en) 1987-01-27 1987-03-04 Patcentre Benelux Nv Sa Pumps
US4938742A (en) 1988-02-04 1990-07-03 Smits Johannes G Piezoelectric micropump with microvalves
US5205819A (en) 1989-05-11 1993-04-27 Bespak Plc Pump apparatus for biomedical use

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3325155A (en) * 1962-05-07 1967-06-13 Equipment Des Ind Chimiques S Valve tray apparatus
US4558995A (en) * 1983-04-25 1985-12-17 Ricoh Company, Ltd. Pump for supplying head of ink jet printer with ink under pressure
JPH02140475A (en) * 1988-11-21 1990-05-30 Seiko Epson Corp Piezoelectric micropump
US5192197A (en) * 1991-11-27 1993-03-09 Rockwell International Corporation Piezoelectric pump
US5611676A (en) * 1994-07-27 1997-03-18 Aisin Seiki Kabushiki Kaisha Micropump

Also Published As

Publication number Publication date
AU1108097A (en) 1997-07-28
IL125140A0 (en) 1999-01-26
WO1997024528A2 (en) 1997-07-10
IL116628A0 (en) 1996-03-31
EP0870110A2 (en) 1998-10-14

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