WO1997009077A1 - Syringe adapter for front-loading medical injector - Google Patents

Syringe adapter for front-loading medical injector Download PDF

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Publication number
WO1997009077A1
WO1997009077A1 PCT/US1996/003191 US9603191W WO9709077A1 WO 1997009077 A1 WO1997009077 A1 WO 1997009077A1 US 9603191 W US9603191 W US 9603191W WO 9709077 A1 WO9709077 A1 WO 9709077A1
Authority
WO
WIPO (PCT)
Prior art keywords
syringe
carrier
adapter
ofthe
follower
Prior art date
Application number
PCT/US1996/003191
Other languages
French (fr)
Inventor
David M. Reilly
Joseph B. Havrilla
Original Assignee
Medrad, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medrad, Inc. filed Critical Medrad, Inc.
Priority to JP51116797A priority Critical patent/JP3471812B2/en
Priority to AT96910393T priority patent/ATE225674T1/en
Priority to DE69624251T priority patent/DE69624251T2/en
Priority to EP96910393A priority patent/EP0847287B1/en
Publication of WO1997009077A1 publication Critical patent/WO1997009077A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14546Front-loading type injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1456Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14566Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1458Means for capture of the plunger flange
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00Surgery
    • Y10S128/01Motorized syringe

Definitions

  • the present invention relates to adapters for releasably attaching syringes to medical injectors, and more particularly to adapters for releasably attaching syringes of various types to front-loading injectors
  • a syringe used with a front-loading injector requires a specially designed readily releasable mounting mechanism for securing the syringe to the front wall of the injector head and a specially designed readily releasable mounting mechanism for securing the syringe plunger to the piston head of the injector
  • These required mounting mechanisms oftentimes increase the cost of the syringes and prohibit the use of syringes of other various types with front-loading injectors
  • Syringes of other various types generally include a syringe body, a plunger reciprocally mounted therein, and a plunger extension engagable by a drive means
  • front- loading injectors have an injector head, including a front wall and an opening formed therein, and a drive member, such as a piston having a piston head, reciprocally mounted within the injector head and extendible through the injector head opening.
  • a syringe of a first type includes a body, a plunger reciprocally mounted therein, and a plunger rod attached to the rear end ofthe plunger and extending axially out of the syringe body.
  • a circumferential flange is disposed about the rear end of the syringe body and a circumferential flange is disposed about the rear end ofthe plunger rod.
  • the syringe adapter of the first embodiment of the invention permits use of a syringe of the first type with a front-loading injector and includes a carrier having a rear end, a front end, and an arcuate channel formed near the front end of the carrier to engage at least a portion of the circumferential flange located at the rear end of the syringe.
  • a pair of mounting flanges is located proximate to the carrier rear end for releasably mounting the carrier in a desired position relative to the front wall of the injector head.
  • the pair of mounting flanges and corresponding pair of receiving flanges of the injector head form a first interlocking mechanism which is activated and released upon rotation of the carrier relative to the front wall of the injector head.
  • the mounting flanges may also include indicating means, such as recesses or notches, which may be read by the injector, by any suitable means, so as to identify the type of syringe and/or adapter installed onto the injector head.
  • the syringe adapter of the first embodiment further includes a follower reciprocally mounted within the carrier.
  • the follower includes a rear end, and a front end having an arcuate channel formed therein for receiving a least a portion of the circumferential flange disposed about the rear end of the syringe plunger rod.
  • a piston head opening and a pair of piston head slots communicating therewith are formed in the rear end of the follower. The piston head opening and piston head slots form a second interlocking mechanism with the piston head which is activated and released upon rotation of the carrier relative to the front wall of the injector head.
  • a syringe of a second type includes a body, a neck portion, a tapered section connecting the body and neck portion, a plunger reciprocally mounted within the body, and a flange circumferentially disposed near the rear end of the body.
  • the syringe of the second type further includes a plunger extension extending from the rear of the plunger, which includes a knob connected to a stem portion When a syringe of the second type is installed into an injector other than a front-loading injector, the knob typically engages the drive means of such injector
  • the adapter of the second embodiment permits use of the second type of syringe with a front-loading injector and includes a carrier having a front end, a rear end and an arcuate channel formed near the rear end ofthe carrier to engage at least a portion ofthe circumferential flange located at the rear end of the syringe
  • a front retaining wall is further provided proximate to the carrier front end for engaging at least a portion of a front tapered section ofthe syringe when the syringe is installed in the carrier
  • a pair of mounting flanges is located proximate to the carrier rear end for releasably mounting the carrier in a desired position relative to the front wall ofthe injector head
  • the pair of mounting flanges and corresponding pair of receiving flanges ofthe injector head form a first interlocking mechanism which is activated and released upon rotation of the carrier relative to the front wall ofthe injector head
  • the syringe adapter of the second embodiment further includes
  • the syringe adapter of the third embodiment of the invention is an alternative to the second embodiment and permits use of a syringe of the second type with a front-loading injector
  • This adapter embodiment includes a carrier having a front end, a rear end and an arcuate channel formed in the carrier to engage at least a portion of the circumferential flange located at the rear end of the syringe
  • the syringe body when installed in the carrier, extends beyond the front end ofthe carrier
  • this embodiment includes a pair of mounting flanges located proximate to the carrier rear end for mounting the carrier in a desired position relative to the front wall of the injector head
  • These mounting flanges operate as described above
  • this embodiment includes a follower having the elements and function similar to the follower of the second embodiment, as described above BRIEF DESCRIPTION OF THE DRAWINGS
  • Fig IA is a perspective, disassembled view of an injector of a front-loading type and a first embodiment of a syringe/adapter combination the present invention
  • Fig IB is a perspective view of the syringe/adapter combination of Fig 1 A loaded onto the front-loading injector of Fig IA
  • Fig IA is a perspective, disassembled view of an injector of a front-loading type and a first embodiment of a syringe/adapter combination the present invention
  • Fig IB is a perspective view of the syringe/adapter combination of Fig 1 A loaded onto the front-loading injector of Fig IA
  • Fig 2 A is a perspective, disassembled view of a syringe and the first embodiment ofthe syringe adapter ofthe present invention
  • Fig 2B is a top view of the first embodiment of an assembled syringe/adapter combination shown in Fig 2 A,
  • Fig 2C is an end view ofthe first embodiment ofthe syringe/adapter combination taken along line 2C-2C of Fig 2B,
  • Fig 2D is a side view ofthe first embodiment ofthe syringe/adapter combination shown in Fig 2B
  • Fig 2E is a bottom view of the first embodiment of the syringe/adapter combination shown in Fig 2B
  • Fig 3 A is a perspective, disassembled view of a syringe and a second embodiment ofthe syringe adapter ofthe present invention
  • Fig 3B is a top view of the second embodiment of an assembled syringe/adapter shown in Fig 3 A,
  • Fig 3 C is an end view of the second embodiment of the syringe/adapter combination taken along line 3C-3C of Fig 3B,
  • Fig 3D is a side view of the second embodiment of the syringe/adapter combination shown in Fig 3B
  • Fig 4A is a perspective, disassembled view of a syringe and a third embodiment of the syringe adapter ofthe present invention
  • Fig 4B is a top view of the third embodiment of an assembled syringe/adapter combination shown in Fig 4A,
  • Fig 4C is an end view of the third embodiment of the syringe/adapter combination taken along line 4C-4C of Fig 4B, and
  • Fig 4D is a side view ofthe third embodiment ofthe syringe/adapter combination shown in Fig 4B DETAILED DESCRIPTION OF THE INVENTION
  • Fig IA shows a disassembled view of a front-loading medical injection system 10 comprising and injector (not shown) having a front-loading injector head 12 onto which a syringe 14 of any type is attached
  • syringe 14 includes a syringe body 16 and a neck portion 20 connected thereto by a tapered portion 18
  • a standard luer connector 22 may also be provided for attaching a fluid delivery path (not shown) to a patient
  • Body 16 may also include a flange 24 circumferentially disposed near its rear end
  • a plunger 28 is reciprocally mounted within the syringe body 16 any may include a plunger extension, such as plunger rod 26 having a flange 30 circumferentially disposed near the rear end of the plunger rod 26
  • the front-loading injector head 12 includes a front wall 31 having an opening 32 formed therein
  • a drive means such as piston 34, is reciprocally mounted within head 12 and is extendible through opening 32
  • Piston 34 includes a piston head 36
  • Receiving flanges 38a and 38b preferably positioned opposite one another, radially extend inwardly into opening 32
  • Receiving slots 40a and 40b preferably positioned opposite one another and between receiving flanges 38a and 38b, respectively, also radially extend inwardly into opening 32
  • the function of receiving flanges 38a and 38b, and receiving slots 40a and 40b, is described below
  • the first embodiment of the syringe adapter 42 of the present invention includes a carrier 44 having a front end 45 and a rear end 46 Means for retaining the syringe, such as circumferential slot 54 or any other suitable mechanism, is provided at the front end 45 of carrier 42 to receive and retain syringe flange 24 within the carrier 42 during an injection procedure
  • the rear end 46 of carrier 42 includes a first readily releasable mounting means, such as a pair of mounting flanges 48a and 48b, for mounting the carrier 44 in a desired position relative to the front wall 31 ofthe injector head 12
  • Mounting flanges 48a and 48b may include indicating means, such as detents or notches 57a and 57b, which provide information to the injector head 12 about the type of syringe 14 or adapter 42 being used
  • the injector head 12 includes any suitable means (not shown) for reading information
  • the adapter ofthe first embodiment further includes a follower 50 reciprocally mounted within the carrier 44 and includes a front end 51 and a rear end 53
  • the front end 51 includes a circumferential slot 52 which receives and retains flange 30 of plunger rod 26 when syringe 14 is installed into adapter 42
  • the rear end 53 of follower 50 includes second readily releasable mounting means, such as piston head opening 55, and piston slots 56a and 56b recessed behind and communicating therewith, for mounting the follower 50 in a desired position relative to the piston head 36.
  • rear end 53 of follower 50 may include various other mechanisms for releasably mounting the follower to the piston head, such as L-shaped members, as taught in U.S.
  • carrier 44 may further include an axial slot 47 for receiving follower alignment peg 58 extending from the bottom of follower 50. As follower alignment peg 58 moves axially within slot 47, it ensures that follower 50 will not rotate within carrier 44 during an injection procedure.
  • follower alignment peg 58 moves axially within slot 47, it ensures that follower 50 will not rotate within carrier 44 during an injection procedure.
  • the operator first insert syringe 14 into adapter 42 such that syringe body flange 24 is received by carrier slot 54 and plunger rod flange 30 is received by follower slot 52.
  • Rear end of adapter 46 is then inserted into injector head opening 32 such that mounting flanges 48a and 48b are inserted into receiving slots 40a and 40b, respectively. If, at this time, follower 50 is not positioned at the rear end 46 of carrier 42 such that piston head opening 55 can engage piston head 36, the piston 34 is moved forward by the operation of the injector to advance the piston head 36 until the piston head 36 is received by the piston head opening 55 of follower 50.
  • Injector head 12 may further include a stop mechanism (not shown) extending from at least one of the retaining slots 38a and 38b, to prevent rotation ofthe adapter/syringe combination more than 90 degrees.
  • the adapter/syringe combination is now securely attached to injector head 12 and the operator can begin the injection procedure.
  • follower 50 applies a motive force to plunger rod 26 which advances plunger 28, thus, forcing fluid in syringe 14 out of neck 20 into the fluid path (not shown) to the patient.
  • the operator grasps the adapter/syringe combination and rotates it 90 degrees back to the pre-installation orientation, thus, disengaging the mountmg flanges 48a and 48b from behind receiving flanges 38a and 38b, respectively, and disengaging piston head 36 from piston slots 56a and 56b
  • the adapter/syringe combination is then removed from the injector head 12
  • a primary advantage of using adapter 42 is that syringe 14 need not include mounting flanges and its plunger 28 need not include means for receiving the piston head, as required by the front-loading syringes taught in U S Patent No 5,383,858 Thus, the cost of syringe 14 is reduced
  • Other advantages of using adapter 42 are that syringe 14 can be loaded onto and removed from injector head 12 without disassembling the fluid path to the patient, and the injector piston 34 may be retracted from adapter/syringe combination without retracting syringe plunger 28, thus, reducing the risk of withdrawing fluid from the patient back into the syringe 14
  • a syringe 300 of a second type may include a syringe body 302 and a neck portion 306 connected thereto by a tapered portion 304
  • a standard luer connector 308 may also be provided for attaching a fluid delivery path (not shown) to a patient
  • Body 302 may further include a flange 310 circumferentially disposed near its rear end
  • a plunger 314 is reciprocally mounted within the syringe body 302 and may include a plunger extension, such as plunger stem 311 having a knob 312 attached thereto
  • knob 312 is typically engaged by the injector drive means
  • the front-loading injector head onto which syringe 300 is releasably attached is similar to the front-loading injector head 12 shown in
  • the second embodiment ofthe syringe adapter 350 ofthe present invention includes a carrier 352 having a front end 355 and a rear end 366 Means for retaining the syringe, such as circumferential slot 364 or any other suitable mechanism, is provided proximate to the rear end 366 of carrier 350 to receive and retain syringe flange 310 within the carrier 350 during an injection procedure
  • a front retaining wall 356 is provided at the front end 355 of carrier 350 and includes an inside surface 358 which engages and retains at least a portion ofthe syringe tapered section 304, and opening 360 which engages and retains at least a portion ofthe syringe neck 306, when syringe 300 is installed into carrier 350
  • the rear end 366 of carrier 350 includes a first readily releasably mounting means, such as a pair of mounting flanges 368a and 368b, for mounting the carrier 350 in
  • the adapter of the second embodiment further includes a follower 370 reciprocally mounted within the carrier 350 and includes a front end 371 and a rear end 373.
  • the front end 371 includes a slot 372 configured to receive the stem 31 1 and knob 312 of plunger 314 when syringe 300 is installed into adapter 350.
  • Fig. 3C shows that rear end 373 of follower 370 includes second readily releasable mounting means, such as piston head opening 375, and piston slots 376a and 376b recessed behind piston opening 375 and communicating therewith, for mounting the follower 370 in a desired position relative to the injector piston head 36.
  • adapter 350 is similar to use of the adapter of the first embodiment.
  • the operator first inserts syringe 300 into adapter 350 such that syringe body flange 310 is received by carrier slot 364, and plunger stem 311 and knob 312 are received by follower slot 372 such that the front end 371 of follower 370 engages the rear surface of plunger 314.
  • Rear end 366 of adapter 350 is then inserted into injector head opening 32 such that mounting flanges 368a and 368b are inserted into injector head receiving slots 40a and 40b, respectively.
  • follower 370 is not positioned at the rear end 366 of carrier 350 such that piston head opening 375 can engage piston head 36, the piston 34 is moved forward by the operation of the injector to advance the piston head 36 until the piston head 36 is received by the piston head opening 375 of follower 370.
  • the operator grasps the adapter/syringe combination and rotates it 90 degrees back to the pre-installation orientation, thus, disengaging the mounting flanges 368a and 368b from behind injector receiving flanges 38a and 38b, respectively, and disengaging piston head 36 from piston slots 376a and 376b
  • the adapter/syringe combination is then removed from the injector head 12
  • the advantages of using the adapter of the first embodiment of the invention are also achieved by using the adapter ofthe second embodiment ofthe invention
  • the third embodiment of syringe adapter ofthe present invention is similar to the second embodiment in that it permits use of a syringe of the second type, as shown in Fig. 3 A, and reproduced in Fig.
  • the adapter 400 of the third embodiment includes a carrier 402 having a front end 403 and a rear end 408 Means for retaining the syringe, such as a circumferential slot 406 or any other suitable mechanism, is formed within carrier 400 to receive and retain syringe flange 310 within the carrier 400 during an injection procedure Unlike the second embodiment, the third embodiment of the adapter does not include the front retaining wall, as previously described
  • the rear end 408 of carrier 400 of the third embodiment includes a first readily releasably mounting means, such as a pair of mounting flanges 410a and 410b, for mounting the carrier 400 in a desired position relative to the front wall 31 ofthe injector head 12
  • Mounting flanges 410a and 410b may further include indicating means, such as detents or notches 411a and 41 1b, which provide syringe and/or adapter information to the injector head 12
  • the adapter 400 of the third embodiment further includes a follower 404 reciprocally mounted within the carrier 400 which includes a front end 405 and a rear end 407 As shown in Fig 4A, the front end 405 includes a slot 414 configured to receive the stem 31 1 and knob 312 of plunger 314 when syringe 300 is installed into adapter 350
  • Fig 4C shows that rear end 407 of follower 404 includes second readily releasable mounting means, such as piston head
  • adapter 400 is similar to use ofthe adapters ofthe first and second embodiments
  • the operator first inserts syringe 300 into adapter 400 such that syringe body flange 310 is received by carrier slot 406, and plunger stem 311 and knob 312 are received by follower slot 414 such that the front end 405 o follower 404 engages the rear surface of plunger 314
  • Rear end 408 of adapter 400 is then inserted into injector head opening 32 such that mounting flanges 410a and 410b are inserted into injector head receiving slots 40a and 40b, respectively.
  • follower 404 is not positioned at the rear end 408 of carrier 400 such that piston head opening 418 can engage piston head 36, the piston 34 is moved forward by the operation of the injector to advance the piston head 36 until the piston head 36 is received by the piston head opening 418 of follower 404.
  • the operator grasps the adapter/syringe combination and rotates it 90 degrees back to the pre-installation orientation, thus, disengaging the mounting flanges 410a and 410b from behind injector receiving flanges 38a and 38b, respectively, and disengaging piston head 36 from piston slots 419a and 419b.
  • the adapter/syringe combination is then removed from the injector head 12.

Abstract

An adapter (42) for releasably attaching syringes (14) of various types to a front-loading injector head (12), the adapter (42) including a syringe carrier (44) having a front end (45), a rear end (46), and syringe retaining channel (54) located between the carrier front and rear ends (45, 46) for engaging at least a portion of syringe flange (24); mounting flanges (48a, 48b) near the carrier rear end (46) for releasably mounting the carrier (44) in a desired position relative to a front wall (31) of the injector head (12); a follower (50) reciprocally mounted within the carrier (44) having a front end (51) engageable with a syringe plunger (28) when the syringe (14) is installed in the carrier (44); and a drive head opening (55) communicating with a pair of drive head slots (56a, 56b) positioned proximate to a rear end (53) of the follower (50) for releasably mounting the follower (50) in a desired position relative to a drive head (36) of the injector.

Description

Descripton SYRINGE ADAPTER FOR FRONT-LOADING MEDICAL INJECTOR TECHNICAL FIELD OF THE INVENTION
The present invention relates to adapters for releasably attaching syringes to medical injectors, and more particularly to adapters for releasably attaching syringes of various types to front-loading injectors
BACKGROUND OF THE INVENTION
Medical injectors and syringes containing fluid, such as contrast media, are commonly used to inject fluid into a patient in a wide variety of diagnostic procedures Injectors of the front-loading type are often used in such procedures U S Patent No 5,383,858, assigned to the common assignee of the present application, provides a detailed description of injectors of the front-loading type and corresponding syringe designs, and is fully incorporated herein by reference One advantage of the front-loading injector of U S Patent No 5,383,858 is that a syringe can readily be loaded onto and removed from the injector head without the need to disconnect the fluid path from the syringe to the patient Another advantage of the front- loading injector of U S Patent No 5,383,858 is that the drive means of the injector head may be disengaged and retracted from the syringe plunger without retracting the syringe plunger, thus substantially reducing the risk of withdrawing fluid from the patient after completion of the diagnostic procedure This feature is also taught in U S Patent No 4,677,980, assigned to the common assignee ofthe present application, and fully incorporated herein by reference
As discussed in U S Patent No 5,383,858, a syringe used with a front-loading injector requires a specially designed readily releasable mounting mechanism for securing the syringe to the front wall of the injector head and a specially designed readily releasable mounting mechanism for securing the syringe plunger to the piston head of the injector These required mounting mechanisms oftentimes increase the cost of the syringes and prohibit the use of syringes of other various types with front-loading injectors Syringes of other various types generally include a syringe body, a plunger reciprocally mounted therein, and a plunger extension engagable by a drive means Thus, it is desirable to design an adapter for use with syringes of various types to permit use of these syringes with front-loading injectors
SUMMARY OF THE INVENTION The present invention relates to adapters for releasably attaching syringes of various types to front-loading injectors. As more fully described in U.S. Patent No. 5,383,858, front- loading injectors have an injector head, including a front wall and an opening formed therein, and a drive member, such as a piston having a piston head, reciprocally mounted within the injector head and extendible through the injector head opening.
By way of example, a syringe of a first type includes a body, a plunger reciprocally mounted therein, and a plunger rod attached to the rear end ofthe plunger and extending axially out of the syringe body. A circumferential flange is disposed about the rear end of the syringe body and a circumferential flange is disposed about the rear end ofthe plunger rod. The syringe adapter of the first embodiment of the invention permits use of a syringe of the first type with a front-loading injector and includes a carrier having a rear end, a front end, and an arcuate channel formed near the front end of the carrier to engage at least a portion of the circumferential flange located at the rear end of the syringe. A pair of mounting flanges is located proximate to the carrier rear end for releasably mounting the carrier in a desired position relative to the front wall of the injector head. The pair of mounting flanges and corresponding pair of receiving flanges of the injector head form a first interlocking mechanism which is activated and released upon rotation of the carrier relative to the front wall of the injector head. The mounting flanges may also include indicating means, such as recesses or notches, which may be read by the injector, by any suitable means, so as to identify the type of syringe and/or adapter installed onto the injector head.
The syringe adapter of the first embodiment further includes a follower reciprocally mounted within the carrier. The follower includes a rear end, and a front end having an arcuate channel formed therein for receiving a least a portion of the circumferential flange disposed about the rear end of the syringe plunger rod. A piston head opening and a pair of piston head slots communicating therewith are formed in the rear end of the follower. The piston head opening and piston head slots form a second interlocking mechanism with the piston head which is activated and released upon rotation of the carrier relative to the front wall of the injector head.
By way of another example, a syringe of a second type includes a body, a neck portion, a tapered section connecting the body and neck portion, a plunger reciprocally mounted within the body, and a flange circumferentially disposed near the rear end of the body. The syringe of the second type further includes a plunger extension extending from the rear of the plunger, which includes a knob connected to a stem portion When a syringe of the second type is installed into an injector other than a front-loading injector, the knob typically engages the drive means of such injector
The adapter of the second embodiment permits use of the second type of syringe with a front-loading injector and includes a carrier having a front end, a rear end and an arcuate channel formed near the rear end ofthe carrier to engage at least a portion ofthe circumferential flange located at the rear end of the syringe A front retaining wall is further provided proximate to the carrier front end for engaging at least a portion of a front tapered section ofthe syringe when the syringe is installed in the carrier Similar to the first embodiment of the invention, a pair of mounting flanges is located proximate to the carrier rear end for releasably mounting the carrier in a desired position relative to the front wall ofthe injector head The pair of mounting flanges and corresponding pair of receiving flanges ofthe injector head form a first interlocking mechanism which is activated and released upon rotation of the carrier relative to the front wall ofthe injector head The syringe adapter of the second embodiment further includes a follower reciprocally mounted within the carrier The follower includes a rear end, and a front end having a radial channel formed therein for receiving the knob and stem of the plunger extension Similar to the first embodiment, a piston head opening and a pair of piston slots communicating therewith are formed in the rear end ofthe follower The piston head opening and piston slots form a second interlocking mechanism with the piston head which is activated and released upon rotation of the carrier relative to the front wall ofthe injector head
The syringe adapter of the third embodiment of the invention is an alternative to the second embodiment and permits use of a syringe of the second type with a front-loading injector This adapter embodiment includes a carrier having a front end, a rear end and an arcuate channel formed in the carrier to engage at least a portion of the circumferential flange located at the rear end of the syringe In this embodiment, the syringe body, when installed in the carrier, extends beyond the front end ofthe carrier Similar to the second embodiment ofthe invention, this embodiment includes a pair of mounting flanges located proximate to the carrier rear end for mounting the carrier in a desired position relative to the front wall of the injector head These mounting flanges operate as described above Further, this embodiment includes a follower having the elements and function similar to the follower of the second embodiment, as described above BRIEF DESCRIPTION OF THE DRAWINGS
Fig IA is a perspective, disassembled view of an injector of a front-loading type and a first embodiment of a syringe/adapter combination the present invention, Fig IB is a perspective view of the syringe/adapter combination of Fig 1 A loaded onto the front-loading injector of Fig IA,
Fig 2 A is a perspective, disassembled view of a syringe and the first embodiment ofthe syringe adapter ofthe present invention,
Fig 2B is a top view of the first embodiment of an assembled syringe/adapter combination shown in Fig 2 A,
Fig 2C is an end view ofthe first embodiment ofthe syringe/adapter combination taken along line 2C-2C of Fig 2B,
Fig 2D is a side view ofthe first embodiment ofthe syringe/adapter combination shown in Fig 2B, Fig 2E is a bottom view of the first embodiment of the syringe/adapter combination shown in Fig 2B,
Fig 3 A is a perspective, disassembled view of a syringe and a second embodiment ofthe syringe adapter ofthe present invention,
Fig 3B is a top view of the second embodiment of an assembled syringe/adapter shown in Fig 3 A,
Fig 3 C is an end view of the second embodiment of the syringe/adapter combination taken along line 3C-3C of Fig 3B,
Fig 3D is a side view of the second embodiment of the syringe/adapter combination shown in Fig 3B, Fig 4A is a perspective, disassembled view of a syringe and a third embodiment of the syringe adapter ofthe present invention,
Fig 4B is a top view of the third embodiment of an assembled syringe/adapter combination shown in Fig 4A,
Fig 4C is an end view of the third embodiment of the syringe/adapter combination taken along line 4C-4C of Fig 4B, and
Fig 4D is a side view ofthe third embodiment ofthe syringe/adapter combination shown in Fig 4B DETAILED DESCRIPTION OF THE INVENTION
Fig IA shows a disassembled view of a front-loading medical injection system 10 comprising and injector (not shown) having a front-loading injector head 12 onto which a syringe 14 of any type is attached By way of example, syringe 14 includes a syringe body 16 and a neck portion 20 connected thereto by a tapered portion 18 A standard luer connector 22 may also be provided for attaching a fluid delivery path (not shown) to a patient Body 16 may also include a flange 24 circumferentially disposed near its rear end A plunger 28 is reciprocally mounted within the syringe body 16 any may include a plunger extension, such as plunger rod 26 having a flange 30 circumferentially disposed near the rear end of the plunger rod 26
The front-loading injector head 12 includes a front wall 31 having an opening 32 formed therein A drive means, such as piston 34, is reciprocally mounted within head 12 and is extendible through opening 32 Piston 34 includes a piston head 36 Receiving flanges 38a and 38b, preferably positioned opposite one another, radially extend inwardly into opening 32 Receiving slots 40a and 40b, preferably positioned opposite one another and between receiving flanges 38a and 38b, respectively, also radially extend inwardly into opening 32 The function of receiving flanges 38a and 38b, and receiving slots 40a and 40b, is described below
The first embodiment of the syringe adapter 42 of the present invention, as shown in Figs IA through 2E, includes a carrier 44 having a front end 45 and a rear end 46 Means for retaining the syringe, such as circumferential slot 54 or any other suitable mechanism, is provided at the front end 45 of carrier 42 to receive and retain syringe flange 24 within the carrier 42 during an injection procedure As best shown in Figs 2A - 2E the rear end 46 of carrier 42 includes a first readily releasable mounting means, such as a pair of mounting flanges 48a and 48b, for mounting the carrier 44 in a desired position relative to the front wall 31 ofthe injector head 12 Mounting flanges 48a and 48b may include indicating means, such as detents or notches 57a and 57b, which provide information to the injector head 12 about the type of syringe 14 or adapter 42 being used Correspondingly, the injector head 12 includes any suitable means (not shown) for reading information from notches 57a and 57b
The adapter ofthe first embodiment further includes a follower 50 reciprocally mounted within the carrier 44 and includes a front end 51 and a rear end 53 The front end 51 includes a circumferential slot 52 which receives and retains flange 30 of plunger rod 26 when syringe 14 is installed into adapter 42 As best shown in Fig 2C, the rear end 53 of follower 50 includes second readily releasable mounting means, such as piston head opening 55, and piston slots 56a and 56b recessed behind and communicating therewith, for mounting the follower 50 in a desired position relative to the piston head 36. It is understood that rear end 53 of follower 50 may include various other mechanisms for releasably mounting the follower to the piston head, such as L-shaped members, as taught in U.S. Patent No. 5,383,858, or any type of clip device. As shown in Figs. 2D and 2E, carrier 44 may further include an axial slot 47 for receiving follower alignment peg 58 extending from the bottom of follower 50. As follower alignment peg 58 moves axially within slot 47, it ensures that follower 50 will not rotate within carrier 44 during an injection procedure. To use the adapter 42 to attach syringe 14 to injector head 12, it is preferred that the operator first insert syringe 14 into adapter 42 such that syringe body flange 24 is received by carrier slot 54 and plunger rod flange 30 is received by follower slot 52. Rear end of adapter 46 is then inserted into injector head opening 32 such that mounting flanges 48a and 48b are inserted into receiving slots 40a and 40b, respectively. If, at this time, follower 50 is not positioned at the rear end 46 of carrier 42 such that piston head opening 55 can engage piston head 36, the piston 34 is moved forward by the operation of the injector to advance the piston head 36 until the piston head 36 is received by the piston head opening 55 of follower 50.
Once mounting flanges 48a and 48b are inserted into receiving slots 40a and 40b, respectively, and the piston head 36 is received by the piston head opening 55, the operator rotates the entire adapter/syringe combination approximately 90 degrees such that mounting flanges 48a and 48b move behind and are engaged by receiving flanges 38a and 38b, respectively, and the piston head 36 moves into piston slots 56a and 56b. Injector head 12 may further include a stop mechanism (not shown) extending from at least one of the retaining slots 38a and 38b, to prevent rotation ofthe adapter/syringe combination more than 90 degrees. The adapter/syringe combination is now securely attached to injector head 12 and the operator can begin the injection procedure. As piston 34 is advanced forward, follower 50 applies a motive force to plunger rod 26 which advances plunger 28, thus, forcing fluid in syringe 14 out of neck 20 into the fluid path (not shown) to the patient.
Once the injection procedure is completed, the operator grasps the adapter/syringe combination and rotates it 90 degrees back to the pre-installation orientation, thus, disengaging the mountmg flanges 48a and 48b from behind receiving flanges 38a and 38b, respectively, and disengaging piston head 36 from piston slots 56a and 56b The adapter/syringe combination is then removed from the injector head 12
A primary advantage of using adapter 42 is that syringe 14 need not include mounting flanges and its plunger 28 need not include means for receiving the piston head, as required by the front-loading syringes taught in U S Patent No 5,383,858 Thus, the cost of syringe 14 is reduced Other advantages of using adapter 42 are that syringe 14 can be loaded onto and removed from injector head 12 without disassembling the fluid path to the patient, and the injector piston 34 may be retracted from adapter/syringe combination without retracting syringe plunger 28, thus, reducing the risk of withdrawing fluid from the patient back into the syringe 14
It is understood that syringes of other configurations may be used with the adapters of the present invention For example, as shown in Fig 3 A, a syringe 300 of a second type may include a syringe body 302 and a neck portion 306 connected thereto by a tapered portion 304 A standard luer connector 308 may also be provided for attaching a fluid delivery path (not shown) to a patient Body 302 may further include a flange 310 circumferentially disposed near its rear end A plunger 314 is reciprocally mounted within the syringe body 302 and may include a plunger extension, such as plunger stem 311 having a knob 312 attached thereto When a syringe of this type is used with an injector other than the front-loading injector described herein, knob 312 is typically engaged by the injector drive means The front-loading injector head onto which syringe 300 is releasably attached is similar to the front-loading injector head 12 shown in Figs 1 A and IB, and previously described
The second embodiment ofthe syringe adapter 350 ofthe present invention, as shown in Figs 3 A through 3D, includes a carrier 352 having a front end 355 and a rear end 366 Means for retaining the syringe, such as circumferential slot 364 or any other suitable mechanism, is provided proximate to the rear end 366 of carrier 350 to receive and retain syringe flange 310 within the carrier 350 during an injection procedure A front retaining wall 356 is provided at the front end 355 of carrier 350 and includes an inside surface 358 which engages and retains at least a portion ofthe syringe tapered section 304, and opening 360 which engages and retains at least a portion ofthe syringe neck 306, when syringe 300 is installed into carrier 350 Similar to the first embodiment ofthe invention, the rear end 366 of carrier 350 includes a first readily releasably mounting means, such as a pair of mounting flanges 368a and 368b, for mounting the carrier 350 in a desired position relative to the front wall 31 of the injector head 12. Mounting flanges 368a and 368b may include indicating means, such as detents or notches 369a and 369b, which provide information to the injector head 12 about the type of syringe 300 or adapter 350 being used.
The adapter of the second embodiment further includes a follower 370 reciprocally mounted within the carrier 350 and includes a front end 371 and a rear end 373. The front end 371 includes a slot 372 configured to receive the stem 31 1 and knob 312 of plunger 314 when syringe 300 is installed into adapter 350. Fig. 3C, shows that rear end 373 of follower 370 includes second readily releasable mounting means, such as piston head opening 375, and piston slots 376a and 376b recessed behind piston opening 375 and communicating therewith, for mounting the follower 370 in a desired position relative to the injector piston head 36.
Use of adapter 350 is similar to use of the adapter of the first embodiment. To attach syringe 300 to injector head 12 of Figs. IA and IB, the operator first inserts syringe 300 into adapter 350 such that syringe body flange 310 is received by carrier slot 364, and plunger stem 311 and knob 312 are received by follower slot 372 such that the front end 371 of follower 370 engages the rear surface of plunger 314. Rear end 366 of adapter 350 is then inserted into injector head opening 32 such that mounting flanges 368a and 368b are inserted into injector head receiving slots 40a and 40b, respectively. If, at this time, follower 370 is not positioned at the rear end 366 of carrier 350 such that piston head opening 375 can engage piston head 36, the piston 34 is moved forward by the operation of the injector to advance the piston head 36 until the piston head 36 is received by the piston head opening 375 of follower 370.
Once mounting flanges 368a and 368b are inserted into injector receiving slots 40a and 40b, respectively, and the piston head 36 is received by the piston head opening 375, the operator rotates the entire adapter/syringe combination approximately 90 degrees such that mounting flanges 368a and 368b move behind and are engaged by receiving flanges 38a and 38b, respectively, and the piston head 36 moves into piston slots 376a and 376b. The adapter/syringe combination is now securely attached to injector head 12 and the operator can begin the injection procedure. As piston 34 is advanced forward, follower 370 applies a motive force to the rear face of plunger 314, thus, forcing fluid in syringe 300 out of neck 306 into the fluid path (not shown) to the patient. Once the injection procedure is completed, the operator grasps the adapter/syringe combination and rotates it 90 degrees back to the pre-installation orientation, thus, disengaging the mounting flanges 368a and 368b from behind injector receiving flanges 38a and 38b, respectively, and disengaging piston head 36 from piston slots 376a and 376b The adapter/syringe combination is then removed from the injector head 12
The advantages of using the adapter of the first embodiment of the invention are also achieved by using the adapter ofthe second embodiment ofthe invention The third embodiment of syringe adapter ofthe present invention is similar to the second embodiment in that it permits use of a syringe of the second type, as shown in Fig. 3 A, and reproduced in Fig. 4A,with a the front-loading injector shown in Figs 1 A and IB As shown in Figs 4A through 4D, the adapter 400 of the third embodiment includes a carrier 402 having a front end 403 and a rear end 408 Means for retaining the syringe, such as a circumferential slot 406 or any other suitable mechanism, is formed within carrier 400 to receive and retain syringe flange 310 within the carrier 400 during an injection procedure Unlike the second embodiment, the third embodiment of the adapter does not include the front retaining wall, as previously described
Similar to the first and second embodiments, the rear end 408 of carrier 400 of the third embodiment includes a first readily releasably mounting means, such as a pair of mounting flanges 410a and 410b, for mounting the carrier 400 in a desired position relative to the front wall 31 ofthe injector head 12 Mounting flanges 410a and 410b may further include indicating means, such as detents or notches 411a and 41 1b, which provide syringe and/or adapter information to the injector head 12 Similar to the second embodiment, the adapter 400 of the third embodiment further includes a follower 404 reciprocally mounted within the carrier 400 which includes a front end 405 and a rear end 407 As shown in Fig 4A, the front end 405 includes a slot 414 configured to receive the stem 31 1 and knob 312 of plunger 314 when syringe 300 is installed into adapter 350 Fig 4C, shows that rear end 407 of follower 404 includes second readily releasable mounting means, such as piston head opening 418, and piston slots 419a and 419b recessed behind piston opening 418 and communicating therewith, for mounting the follower 404 in a desired position relative to the piston head 36
Use of adapter 400 is similar to use ofthe adapters ofthe first and second embodiments To attach syringe 300 to injector head 12 of Figs IA and IB, the operator first inserts syringe 300 into adapter 400 such that syringe body flange 310 is received by carrier slot 406, and plunger stem 311 and knob 312 are received by follower slot 414 such that the front end 405 o follower 404 engages the rear surface of plunger 314 Rear end 408 of adapter 400 is then inserted into injector head opening 32 such that mounting flanges 410a and 410b are inserted into injector head receiving slots 40a and 40b, respectively. If, at this time, follower 404 is not positioned at the rear end 408 of carrier 400 such that piston head opening 418 can engage piston head 36, the piston 34 is moved forward by the operation of the injector to advance the piston head 36 until the piston head 36 is received by the piston head opening 418 of follower 404.
Once mounting flanges 410a and 410b are inserted into injector receiving slots 40a and 40b, respectively, and the piston head 36 is received by the piston head opening 418, the operator rotates the entire adapter/syringe combination approximately 90 degrees such that mounting flanges 410a and 410b move behind and are engaged by receiving flanges 38a and 38b, respectively, and the piston head 36 moves into piston slots 419a and 419b. The adapter/syringe combination is now securely attached to injector head 12 and the operator can begin the injection procedure. As piston 34 is advanced forward, follower 404 applies a motive force to the rear face of plunger 314, thus, forcing fluid in syringe 300 out of neck 306 into the fluid path (not shown) to the patient. Once the injection procedure is completed, the operator grasps the adapter/syringe combination and rotates it 90 degrees back to the pre-installation orientation, thus, disengaging the mounting flanges 410a and 410b from behind injector receiving flanges 38a and 38b, respectively, and disengaging piston head 36 from piston slots 419a and 419b. The adapter/syringe combination is then removed from the injector head 12. The advantages of using the adapter of the first embodiment of the invention are also achieved by using the adapter ofthe third embodiment ofthe invention.
Although the syringe adapters of the invention have been described in detail for the purpose of illustration, it is to be understood that such detail is solely for that purpose and that variations can be made thereto by those skilled in the art without departing from the spirit and scope of the invention except as it may be limited by the claims.

Claims

WE CLAIM
1 An adapter for releasably attaching a syringe to a front-loading injector head, wherein the syringe includes a body, and a plunger reciprocally mounted therein, and wherein the injector head includes a front wall, an opening formed therein, and a drive member having a drive head reciprocally mounted within the injector head and extendible through the opening, the adapter comprising a syringe carrier having a front end, a rear end, and syringe retaining means located between the carrier front end and rear end for engaging at least a portion ofthe syringe to retain the syringe within at least a portion ofthe carrier during an injection procedure, first readily releasable mounting means positioned proximate to the carrier rear end for mounting the carrier in a desired position relative to the front wall ofthe injector head, a follower reciprocally mounted within the carrier and including a front end and a rear end, the front end engagable with the syringe plunger when the syringe is installed in the carrier, and second readily releasable mounting means positioned proximate to the rear end of the follower for mounting the follower in a desired position relative to the drive head
2 The adapter of Claim 1 wherein the syringe retaining means is positioned proximate to the carrier front end
3 The adapter of Claim 1 wherein the syringe retaining means is positioned proximate to the carrier rear end
4 The adapter of Claim 1 wherein the syringe retaining means includes a channel for receiving at least a portion of a flange disposed proximate to a rear end ofthe syringe body
5 The adapter of Claim 1 wherein the carrier further comprises a front retaining wall positioned proximate to the carrier front end for engaging at least a portion of a front tapered section ofthe syringe
6 The adapter of Claim 1 wherein the first readily releasable mounting means is engagable with a first readily releasable receiving means positioned proximate the injector head opening to form a first interlocking mechamsm which is activated and released upon rotation of the carrier relative to the front wall ofthe injector head
7 The adapter of Claim 1 wherein the first readily releasable mounting means includes at least one mounting flange extending radially outward proximate to the rear end of the carrier, the mounting flange releasably engagable with at least one receiving flange extending radially inward proximate to the opening in the front wall ofthe injector head upon rotation ofthe carrier relative to the front wall ofthe injector head
8 The adapter of Claim 7 wherein the mounting flange includes indication means for providing information identifying at least one ofthe syringe and adapter loaded onto the injector head
9 The adapter of Claim 1 wherein the follower includes means for releasably receiving at least a portion of a plunger extension extending from a rear end ofthe plunger
10 The adapter of Claim 9 wherein the plunger extension includes a plunger rod attached at a first end to the plunger and having a flange disposed proximate to a second end ofthe plunger rod, and the means for releasably receiving at least a portion of the plunger extension includes means for releasably receiving at least a portion ofthe plunger rod flange
11 The adapter of Claim 10 wherem the means for releasably receiving at least a portion of the plunger rod flange includes a channel formed proximate to the front end ofthe follower
12 The adapter of Claim 9 wherein the plunger extension includes a stem attached at a first end to the plunger and knob attached to a second end ofthe stem, and the means for releasably receiving at least a portion of the plunger extension includes means for releasably receiving at least a portion ofthe stem and knob.
13 The adapter of Claim 12 wherein the means for releasably receiving at least a portion of the stem and knob includes a channel formed proximate to the front end of the follower, the channel radially extending from an edge ofthe follower to a center ofthe follower
14 The adapter of Claim 1 wherein the second readily releasable mounting means is engagable with the injector drive head to form a second interlocking mechanism which is activated and released upon rotation of the carrier relative to the front wall ofthe injector head
15 The adapter of Claim 1 wherein the second readily releasable mounting means includes a drive head opening and a pair of drive head slots communicating therewith, the drive head opening and drive head slots releasably engagable with the drive head upon rotation of the carrier relative to the front wall of the injector head
16 A syringe system for use with a front-loading injector head wherein the injector head includes a front wall and an opening formed therein, and a drive member having a drive head reciprocally mounted within the injector head and extendible through the opening, the system comprising a syringe including a body, and a plunger reciprocally mounted therein, and an adapter for receiving the syringe and including a carrier having a front end, a rear end, and syringe retaining means located between the carrier front and rear ends for engaging at least a portion of the syringe to retain the syringe within the carrier during an injection procedure, first readily releasable mounting means positioned proximate to the carrier rear end for mounting the carrier in a desired position relative to the front wall ofthe injector housing; a follower reciprocally mounted within the carrier and including a front end and a rear end, the front end engagable with the syringe plunger when the syringe is installed in the carrier; and second readily releasable mounting means positioned proximate to the rear end ofthe follower for mounting the follower in a desired position relative to the drive head.
17. The syringe system of Claim 16 wherein the first readily releasable mounting means is engagable with a first readily releasable receiving means positioned proximate the injector head opening to form a first interlocking mechanism which is activated and released upon rotation of the carrier relative to the front wall ofthe injector head.
18. The syringe system of Claim 16 wherein the follower includes means for releasably receiving at least a portion of a plunger extension extending from a rear end ofthe plunger.
19. The syringe system of Claim 18 wherein the means for releasably receiving at least a portion ofthe plunger extension includes a channel formed proximate to the front end ofthe follower.
20. The syringe system of Claim 16 wherein the second readily releasable mounting means is engagable with the injector drive head to form a second interlocking mechanism which is activated and released upon rotation of the carrier relative to the front wall ofthe injector head.
PCT/US1996/003191 1995-09-01 1996-03-08 Syringe adapter for front-loading medical injector WO1997009077A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP51116797A JP3471812B2 (en) 1995-09-01 1996-03-08 Front-loading medical injector syringe adapter
AT96910393T ATE225674T1 (en) 1995-09-01 1996-03-08 SYRINGE ADAPTER FOR MEDICAL FRONT LOADING INJECTOR
DE69624251T DE69624251T2 (en) 1995-09-01 1996-03-08 SPRAY ADAPTER FOR MEDICAL FRONT LOADER INJECTOR
EP96910393A EP0847287B1 (en) 1995-09-01 1996-03-08 Syringe adapter for front-loading medical injector

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/522,777 US5520653A (en) 1995-09-01 1995-09-01 Syringe adapter for front-loading medical injector
US08/522,777 1995-09-01

Publications (1)

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WO1997009077A1 true WO1997009077A1 (en) 1997-03-13

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US (1) US5520653A (en)
EP (2) EP0987040B1 (en)
JP (1) JP3471812B2 (en)
AT (2) ATE225674T1 (en)
DE (2) DE69635194T2 (en)
WO (1) WO1997009077A1 (en)

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ATE304377T1 (en) 2005-09-15
DE69624251T2 (en) 2003-06-18
EP0987040A1 (en) 2000-03-22
ATE225674T1 (en) 2002-10-15
DE69635194T2 (en) 2006-06-14
EP0847287B1 (en) 2002-10-09
EP0847287A1 (en) 1998-06-17
JP3471812B2 (en) 2003-12-02
US5520653A (en) 1996-05-28
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JPH11512016A (en) 1999-10-19
DE69635194D1 (en) 2005-10-20

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