WO1996039226A1 - Method of treatment using electroporation-mediated delivery of drugs and genes - Google Patents
Method of treatment using electroporation-mediated delivery of drugs and genes Download PDFInfo
- Publication number
- WO1996039226A1 WO1996039226A1 PCT/US1996/007470 US9607470W WO9639226A1 WO 1996039226 A1 WO1996039226 A1 WO 1996039226A1 US 9607470 W US9607470 W US 9607470W WO 9639226 A1 WO9639226 A1 WO 9639226A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- electrodes
- tissue
- array
- needle
- needles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
Abstract
Description
Claims
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002218255A CA2218255C (en) | 1995-06-06 | 1996-05-22 | Method of treatment using electroporation-mediated delivery of drugs and genes |
EP96916550A EP0874663B1 (en) | 1995-06-06 | 1996-05-22 | Apparatus for treatment using electroporation-mediated delivery of drugs and genes |
MX9708316A MX9708316A (en) | 1995-09-29 | 1996-05-22 | Method of treatment using electroporation-mediated delivery of drugs and genes. |
DE69604509T DE69604509T2 (en) | 1995-06-06 | 1996-05-22 | DEVICE FOR ADMINISTRATING MEDICINES AND GENES BY ELECTROPORATION |
JP9500675A JPH11506630A (en) | 1995-06-06 | 1996-05-22 | Treatment method using electroporation of drug and gene |
DK96916550T DK0874663T3 (en) | 1996-05-22 | 1996-05-22 | Method of treatment using electroporation mediated delivery of drugs and genes |
AU59259/96A AU702054B2 (en) | 1995-06-06 | 1996-05-22 | Method of treatment using electroporation-mediated delivery of drugs and genes |
GR990403056T GR3031963T3 (en) | 1995-06-06 | 1999-11-25 | Method of treatment using electroporation-mediated delivery of drugs and genes |
US10/177,560 US6569149B2 (en) | 1993-04-01 | 2002-06-21 | Method of treatment using electroporation mediated delivery of drugs and genes |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/467,566 US5702359A (en) | 1995-06-06 | 1995-06-06 | Needle electrodes for mediated delivery of drugs and genes |
US08/467,566 | 1995-06-06 | ||
US08/537,265 US5993434A (en) | 1993-04-01 | 1995-09-29 | Method of treatment using electroporation mediated delivery of drugs and genes |
US08/537,265 | 1995-09-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1996039226A1 true WO1996039226A1 (en) | 1996-12-12 |
Family
ID=27042102
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1996/007470 WO1996039226A1 (en) | 1993-04-01 | 1996-05-22 | Method of treatment using electroporation-mediated delivery of drugs and genes |
Country Status (12)
Country | Link |
---|---|
US (6) | US5993434A (en) |
EP (1) | EP0874663B1 (en) |
JP (1) | JPH11506630A (en) |
KR (1) | KR100260238B1 (en) |
CN (1) | CN1150950C (en) |
AT (1) | ATE185083T1 (en) |
AU (1) | AU702054B2 (en) |
CA (1) | CA2218255C (en) |
DE (1) | DE69604509T2 (en) |
ES (1) | ES2140096T3 (en) |
GR (1) | GR3031963T3 (en) |
WO (1) | WO1996039226A1 (en) |
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- 1999-11-25 GR GR990403056T patent/GR3031963T3/en unknown
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- 2000-04-18 US US09/551,327 patent/US6418341B1/en not_active Expired - Lifetime
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- 2002-01-17 US US10/053,861 patent/US6567694B2/en not_active Expired - Lifetime
- 2002-06-21 US US10/177,560 patent/US6569149B2/en not_active Expired - Lifetime
- 2002-08-06 US US10/213,514 patent/US6763264B2/en not_active Expired - Lifetime
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US6939862B2 (en) * | 1997-06-30 | 2005-09-06 | Aventis Pharma S.A. | Method for transferring nucleic acid into striated muscles |
US6521430B1 (en) | 1997-11-06 | 2003-02-18 | Cellectricon Ab | Method for electro-permeabilization of individual cellular and organellar structures and use thereof |
WO1999024110A1 (en) * | 1997-11-06 | 1999-05-20 | A?+¿ Science Invest Ab | Method for electro-permeabilisation of individual cellular and organellar structures and use thereof |
US8338150B2 (en) | 1997-11-06 | 2012-12-25 | Cellectricon Ab | Method for combined parallel agent delivery and electroporation for cell structures an use thereof |
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US10376692B2 (en) | 2002-07-04 | 2019-08-13 | Inovio As | Electroporation device and injection apparatus |
US11471675B2 (en) | 2002-07-04 | 2022-10-18 | Inovio Pharmaceuticals, Inc. | Electroporation device and injection apparatus |
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Also Published As
Publication number | Publication date |
---|---|
EP0874663A1 (en) | 1998-11-04 |
AU702054B2 (en) | 1999-02-11 |
US20030009148A1 (en) | 2003-01-09 |
US5993434A (en) | 1999-11-30 |
JPH11506630A (en) | 1999-06-15 |
ES2140096T3 (en) | 2000-02-16 |
US6451002B1 (en) | 2002-09-17 |
CA2218255A1 (en) | 1996-12-12 |
CN1150950C (en) | 2004-05-26 |
CA2218255C (en) | 2001-11-20 |
KR100260238B1 (en) | 2000-07-01 |
US20030097089A1 (en) | 2003-05-22 |
KR19990021949A (en) | 1999-03-25 |
US6418341B1 (en) | 2002-07-09 |
US6567694B2 (en) | 2003-05-20 |
ATE185083T1 (en) | 1999-10-15 |
DE69604509D1 (en) | 1999-11-04 |
EP0874663B1 (en) | 1999-09-29 |
CN1187145A (en) | 1998-07-08 |
DE69604509T2 (en) | 2000-01-13 |
US6763264B2 (en) | 2004-07-13 |
GR3031963T3 (en) | 2000-03-31 |
US6569149B2 (en) | 2003-05-27 |
AU5925996A (en) | 1996-12-24 |
US20020198485A1 (en) | 2002-12-26 |
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