WO1996035372A3 - A system for quantitative radiographic imaging - Google Patents

A system for quantitative radiographic imaging Download PDF

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Publication number
WO1996035372A3
WO1996035372A3 PCT/US1996/006838 US9606838W WO9635372A3 WO 1996035372 A3 WO1996035372 A3 WO 1996035372A3 US 9606838 W US9606838 W US 9606838W WO 9635372 A3 WO9635372 A3 WO 9635372A3
Authority
WO
WIPO (PCT)
Prior art keywords
image
ccd
scintillation screen
sensor
radiographic imaging
Prior art date
Application number
PCT/US1996/006838
Other languages
French (fr)
Other versions
WO1996035372A2 (en
Inventor
Andrew Karellas
Original Assignee
Univ Massachusetts Medical
Andrew Karellas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/438,800 external-priority patent/US7330531B1/en
Priority to DE69635168T priority Critical patent/DE69635168D1/en
Priority to JP53432496A priority patent/JP4177892B2/en
Priority to CA002218127A priority patent/CA2218127C/en
Priority to EP96915772A priority patent/EP0957766B1/en
Priority to AT96915772T priority patent/ATE303754T1/en
Application filed by Univ Massachusetts Medical, Andrew Karellas filed Critical Univ Massachusetts Medical
Publication of WO1996035372A2 publication Critical patent/WO1996035372A2/en
Publication of WO1996035372A3 publication Critical patent/WO1996035372A3/en
Priority to EP97925548A priority patent/EP0914060A1/en
Priority to PCT/US1997/008102 priority patent/WO1997042877A1/en
Priority to JP54106897A priority patent/JP4063324B2/en
Priority to CA002254877A priority patent/CA2254877A1/en
Priority to US09/896,427 priority patent/US6717174B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/06—Diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/40—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for generating radiation specially adapted for radiation diagnosis
    • A61B6/4035—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for generating radiation specially adapted for radiation diagnosis the source being combined with a filter or grating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/40—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for generating radiation specially adapted for radiation diagnosis
    • A61B6/405—Source units specially adapted to modify characteristics of the beam during the data acquisition process
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/42—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4233—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector using matrix detectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/42—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4241—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector using energy resolving detectors, e.g. photon counting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/42—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4258—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector for detecting non x-ray radiation, e.g. gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50—Clinical applications
    • A61B6/502—Clinical applications involving diagnosis of breast, i.e. mammography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50—Clinical applications
    • A61B6/505—Clinical applications involving diagnosis of bone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50—Clinical applications
    • A61B6/508—Clinical applications for non-human patients
    • A61B6/512—
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21K—TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
    • G21K1/00—Arrangements for handling particles or ionising radiation, e.g. focusing or moderating
    • G21K1/10—Scattering devices; Absorbing devices; Ionising radiation filters
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21K—TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
    • G21K4/00—Conversion screens for the conversion of the spatial distribution of X-rays or particle radiation into visible images, e.g. fluoroscopic screens
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/30—Cameras or camera modules comprising electronic image sensors; Control thereof for generating image signals from X-rays
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/50—Constructional details
    • H04N23/54—Mounting of pick-up tubes, electronic image sensors, deviation or focusing coils
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N5/00—Details of television systems
    • H04N5/30—Transforming light or analogous information into electric information
    • H04N5/32—Transforming X-rays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0091—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for mammography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/42—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4291—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis the detector being combined with a grid or grating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/44—Constructional features of apparatus for radiation diagnosis
    • A61B6/4423—Constructional features of apparatus for radiation diagnosis related to hygiene or sterilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/44—Constructional features of apparatus for radiation diagnosis
    • A61B6/4488—Means for cooling

Abstract

A system for spectroscopic imaging of bodily tissue in which a scintillation screen (20) and a charged coupled device (24) (CCD) are used to accurately image selected tissue. An x-ray source (12) generates X-rays which pass through a region of a subject's body, forming an X-ray image which reaches the scintillation screen (20). The scintillation screen (20) reradiates a spatial intensity pattern corresponding to the image, the pattern being detected by a CCD sensor (24). The image is digitized by the sensor (24) and processed by a controller (30) before being stored as an electronic image. Each image is directed onto an associated respective CCD or amorphous silicon detector to generate individual electronic representations of the separate images.
PCT/US1996/006838 1989-12-05 1996-05-13 A system for quantitative radiographic imaging WO1996035372A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
DE69635168T DE69635168D1 (en) 1995-05-11 1996-05-13 ARRANGEMENT FOR QUANTITATIVE IMAGE DISPLAY BY X-RAY RADIATION
JP53432496A JP4177892B2 (en) 1995-05-11 1996-05-13 Apparatus for quantitative radiographic imaging.
CA002218127A CA2218127C (en) 1995-05-11 1996-05-13 A system for quantitative radiographic imaging
EP96915772A EP0957766B1 (en) 1995-05-11 1996-05-13 A system for quantitative radiographic imaging
AT96915772T ATE303754T1 (en) 1995-05-11 1996-05-13 ARRANGEMENT FOR QUANTITATIVE IMAGING USING X-RAY
EP97925548A EP0914060A1 (en) 1996-05-13 1997-05-13 A system for quantitative radiographic imaging
CA002254877A CA2254877A1 (en) 1996-05-13 1997-05-13 A system for quantitative radiographic imaging
JP54106897A JP4063324B2 (en) 1996-05-13 1997-05-13 System for quantitative radiography
PCT/US1997/008102 WO1997042877A1 (en) 1996-05-13 1997-05-13 A system for quantitative radiographic imaging
US09/896,427 US6717174B2 (en) 1989-12-05 2001-06-29 System for quantitative radiographic imaging

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/438,800 1995-05-11
US08/438,800 US7330531B1 (en) 1989-12-05 1995-05-11 System for quantitative radiographic imaging
US08/469,895 US6031892A (en) 1989-12-05 1995-06-06 System for quantitative radiographic imaging
US08/469,895 1995-06-06

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US08/469,895 Continuation-In-Part US6031892A (en) 1989-12-05 1995-06-06 System for quantitative radiographic imaging

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US08/748,384 Continuation-In-Part US5864146A (en) 1989-12-05 1996-11-13 System for quantitative radiographic imaging

Publications (2)

Publication Number Publication Date
WO1996035372A2 WO1996035372A2 (en) 1996-11-14
WO1996035372A3 true WO1996035372A3 (en) 1997-01-30

Family

ID=27031801

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/006838 WO1996035372A2 (en) 1989-12-05 1996-05-13 A system for quantitative radiographic imaging

Country Status (7)

Country Link
US (6) US6031892A (en)
EP (1) EP0957766B1 (en)
JP (1) JP4177892B2 (en)
AT (1) ATE303754T1 (en)
CA (1) CA2218127C (en)
DE (1) DE69635168D1 (en)
WO (1) WO1996035372A2 (en)

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