WO1996033773A2 - Improvements in or relating to cosmetic treatment of skin lines - Google Patents

Improvements in or relating to cosmetic treatment of skin lines Download PDF

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Publication number
WO1996033773A2
WO1996033773A2 PCT/GB1996/001003 GB9601003W WO9633773A2 WO 1996033773 A2 WO1996033773 A2 WO 1996033773A2 GB 9601003 W GB9601003 W GB 9601003W WO 9633773 A2 WO9633773 A2 WO 9633773A2
Authority
WO
WIPO (PCT)
Prior art keywords
skin
cosmetic treatment
treated
light
minutes
Prior art date
Application number
PCT/GB1996/001003
Other languages
French (fr)
Other versions
WO1996033773A3 (en
Inventor
Marianne Olavesen-Broad
Original Assignee
Olavesen Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olavesen Limited filed Critical Olavesen Limited
Priority to AU54059/96A priority Critical patent/AU5405996A/en
Publication of WO1996033773A2 publication Critical patent/WO1996033773A2/en
Publication of WO1996033773A3 publication Critical patent/WO1996033773A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0616—Skin treatment other than tanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/203—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser applying laser energy to the outside of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452—Skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452—Skin
    • A61B2018/0047—Upper parts of the skin, e.g. skin peeling or treatment of wrinkles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A61N2005/0663—Coloured light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent

Definitions

  • the present invention relates to cosmetic treatment of skin lines.
  • Lines appear on the skin as one ages and many regard them as undesirable, particularly those line that appear on the face and neck.
  • Significant sums of money are spent annually on beauty products such as creams or ointments aimed at reducing such lines or at least slowing their progress.
  • a method of cosmetic treatment of skin lines comprising the steps of exposing an area to be treated to orange light of wavelength in the range 585-560 nano metres and frequency 460-510 x 10 ⁇ : hertz for a period in the range 15 to 25 minutes, followed by yellow light of wavelength 575-585 nano metres and frequency 510-520x10 ' hertz for a period in the range 4 to 6 minutes.
  • the skin to be treated is initially covered with collagen skin food prior to light being directed thereat.
  • the area to be treated is exposed to orange light for 20 minutes and the yellow light for 5 minutes.
  • the light source is positioned at a distance of 15 centimetres from the area to be treated.
  • Figure 1 shows a plan view of a cast taken from skin around the left eye of a first subject before treatment as described in Example 1 :
  • Figure 2 shows a plan view of a cast taken from the skin around the left eye of a first subject after a first treatment according to the present invention, as described in Example 1 :
  • Figure 3 shows a plan view of a cast taken from the skin around the left eye of a first subject after a second treatment according to the present invention, as described in Example
  • Figure 4 shows sectioned end views of casts taken from skin around the right eye of a first subject before treatment and after first and second treatments according to the present invention, as described in Example 1 ;
  • Figure 5 shows perspective end views of the casts of figure 4.
  • Figures 6 to 8 shows plan views of casts taken from skin area around the left eye of a second subject before treatment and after first and second treatments according to the present invention, as described in Example 2:
  • Figure 9 shows an end view of a section through the casts of figures 6 and 8:
  • Figure 10 shows a perspective end view of the casts of figure 9:
  • Figures 1 1 to 13 show plan views of casts taken from skin around the left eye of a third subject as described in Example 3.
  • the cosmetic treatment of the present application uses the known technique of chromotherapy whereby skin is exposed to controlled quantities of coloured light obtained by filtering the output of electric lamps.
  • the machine used to produce the light is an Aurora 200SLR unit which has two articulated arms with end pods. Each pod contains a halogen lamp rated at 50 Watts. 24 Volts and an associated condenser lens. In front of the lens is a filter holder into which may be placed spectrally selective colour filters.
  • the machine In order to treat fine skin lines such as those found on the face and neck the machine is used to direct light at the skin in a specific sequence of colours and with specific timing as described below.
  • the skin food is of a known composition and comprises the following ingredients: purified water: soya oil: tsopropylmyristate: stearic acid: glycerine: jojoba oil: triethanolamine: collagen: octyl dimethyl PABA: synthetic beeswax: cetyl alcohol: diemethicone: carbomer: phenoxy ethanol butyl paraben: fragrance and colouring.
  • the orange filters are placed into the lamp pods so that when the lamps are switched on orange light of wavelength 585-560 nano metres and frequency 460 x 10 * hertz is produced.
  • the lamps are positioned at a distance of 6 inches ( 15 centimetres) from the area to be treated.
  • the machine is then switched on and the light intensity is set to maximum.
  • the treatment area is subjected to the orange light for a period of 20 minutes. Thereafter the filters are removed using a clean cloth to prevent fingerprint contamination (which may reduce the effectiveness of the treatment) and vellow filters are installed.
  • the yellow filters provide yellow light of wavelength 575-585 nano metres and frequency 510 x l ⁇ ' ⁇ hertz and this is directed at the treatment area for a period of 5 minutes at maximum intensity.
  • the light machine is then switched off and removed.
  • the patient remains in position for five minutes to relax.
  • the method described above may be applied to other marking of the skin such as stretch marks.
  • a first subject being a male aged 45 was treated by taking a first cast from the skin area around the left and right eyes.
  • the cast impression of around the left eye is shown in plan in figure 1.
  • the cast around the right eye was sliced to enable the mould profile to be inspected and the result is shown in the top cast section of the photograph shown in figure 2.
  • the significant creases represented by peaks in the cast section are marked with the letters A to F.
  • a scale with 1mm divisions is shown at the bottom of the photograph.
  • the top cast section in the photograph of figure 3 shows an angled view of the same cast with the peaks labelled in the same manner as in figure 2.
  • the area of skin around the left and right eyes of the first subject was then exposed to orange light of wavelength 585-650 nano metres for a period of twenty minutes followed by exposure to yellow light of wavelength 575-585 nano metres for a period of six minutes.
  • Figures 9 and 10 show sections through the casts before treatment (top) and after the second treatment (bottom). Again a 1mm scale is shown at the bottom of figure 9 and the middle of figure 10. Selected main elevations in the cast (representing lines in the skin) before treatment have been identified with the letters A to H. It will be seen that after treatment (bottom cast in each figure) only elevation F remains prominent at the cross- section. Elevations A. B. D. E. G and H are significantly diminished whereas C (perhaps the largest elevation before treatment) has disappeared completely. Again it will be apparent from figures 8 and 10 that the general surface texture of the skin is significantly smoother.
  • Figures 1 1 to 13 show, respectively, castings taken from around the left eye of a third subject: a female aged 60. It will be seen that the number, height and length of each elevation has been reduced dramatically leaving only few elevations that are just visible without magnification.

Abstract

A method of cosmetic treatment of skin lines involves covering the skin to be treated on a patient with collagen skin food. A lamp with colour filter is directed at the area to be treated. Initially orange light of wavelength in the range 585-560 nanometres and frequency 460-510 x 1012 hertz is directed at the treatment area for a period in the range 15 to 25 minutes. Thereafter, the treatment area is exposed to yellow light of wavelength 575-585 nanometres and frequency 510-520 x 1012 hertz for a period in the range 4 to 6 minutes.

Description

IMPROVEMENTS IN OR RELATING TO COSMETIC TREATMENT OF SKIN
LINES
The present invention relates to cosmetic treatment of skin lines.
Lines appear on the skin as one ages and many regard them as undesirable, particularly those line that appear on the face and neck. Significant sums of money are spent annually on beauty products such as creams or ointments aimed at reducing such lines or at least slowing their progress.
According to the present invention there is provided a method of cosmetic treatment of skin lines comprising the steps of exposing an area to be treated to orange light of wavelength in the range 585-560 nano metres and frequency 460-510 x 10ι : hertz for a period in the range 15 to 25 minutes, followed by yellow light of wavelength 575-585 nano metres and frequency 510-520x10 ' hertz for a period in the range 4 to 6 minutes.
Preferably the skin to be treated is initially covered with collagen skin food prior to light being directed thereat.
Preferably the area to be treated is exposed to orange light for 20 minutes and the yellow light for 5 minutes.
Preferably the light source is positioned at a distance of 15 centimetres from the area to be treated.
A specific embodiment of the present invention will now be described by way of example only with reference to the accompanying figures in which:
Figure 1 shows a plan view of a cast taken from skin around the left eye of a first subject before treatment as described in Example 1 :
Figure 2 shows a plan view of a cast taken from the skin around the left eye of a first subject after a first treatment according to the present invention, as described in Example 1 :
Figure 3 shows a plan view of a cast taken from the skin around the left eye of a first subject after a second treatment according to the present invention, as described in Example
1 ;
Figure 4 shows sectioned end views of casts taken from skin around the right eye of a first subject before treatment and after first and second treatments according to the present invention, as described in Example 1 ;
Figure 5 shows perspective end views of the casts of figure 4. Figures 6 to 8 shows plan views of casts taken from skin area around the left eye of a second subject before treatment and after first and second treatments according to the present invention, as described in Example 2:
Figure 9 shows an end view of a section through the casts of figures 6 and 8:
Figure 10 shows a perspective end view of the casts of figure 9: and
Figures 1 1 to 13 show plan views of casts taken from skin around the left eye of a third subject as described in Example 3.
The cosmetic treatment of the present application uses the known technique of chromotherapy whereby skin is exposed to controlled quantities of coloured light obtained by filtering the output of electric lamps.
The machine used to produce the light is an Aurora 200SLR unit which has two articulated arms with end pods. Each pod contains a halogen lamp rated at 50 Watts. 24 Volts and an associated condenser lens. In front of the lens is a filter holder into which may be placed spectrally selective colour filters.
In order to treat fine skin lines such as those found on the face and neck the machine is used to direct light at the skin in a specific sequence of colours and with specific timing as described below.
First, the area of skin on the patient to be treated is cleansed. Collagen skin food is then applied to the area of skin to be treated. The skin food is of a known composition and comprises the following ingredients: purified water: soya oil: tsopropylmyristate: stearic acid: glycerine: jojoba oil: triethanolamine: collagen: octyl dimethyl PABA: synthetic beeswax: cetyl alcohol: diemethicone: carbomer: phenoxy ethanol butyl paraben: fragrance and colouring.
Secondly the orange filters are placed into the lamp pods so that when the lamps are switched on orange light of wavelength 585-560 nano metres and frequency 460 x 10 * hertz is produced. The lamps are positioned at a distance of 6 inches ( 15 centimetres) from the area to be treated.
The machine is then switched on and the light intensity is set to maximum. The treatment area is subjected to the orange light for a period of 20 minutes. Thereafter the filters are removed using a clean cloth to prevent fingerprint contamination (which may reduce the effectiveness of the treatment) and vellow filters are installed. The yellow filters provide yellow light of wavelength 575-585 nano metres and frequency 510 x lθ'~ hertz and this is directed at the treatment area for a period of 5 minutes at maximum intensity.
The light machine is then switched off and removed. The patient remains in position for five minutes to relax.
The method described above produces significant reduction in the number of skin lines and their depth which heretofore has been unmatched by comparable techniques.
The method described above may be applied to other marking of the skin such as stretch marks.
Examples
In order to demonstrate the effectiveness of the cosmetic treatment several subjects were treated according to the present invention to reduce the depth of facial creases around the eye where wrinkles are most prominent and variable in depth. To capture the facial creases from each subject a catalyst-cured silicone rubber impression material, commonly used in dental work and capable of reproducing the fine detail of surface textures, was used. Mouldings were taken from selected facial skin zones around the eyes of each subject. The impression material was manually applied to skin area around the eye with even pressure and on removal a negative impression of the skin surface was obtained i.e the elevations on each removed cast represented the furrows of the facial creases. This technique permitted a cross- section of each cast to be obtained by slicing through the moulded impression material after removal. Each subject was instructed to maintain a consistent facial expression throughout the casting process to avoid stretching or creasing of the skin. After each cast was removed it was cut carefully at right angles to allow assessment of their surface profiles. The thin rubber sections carrying negative impressions of the skin were rigid but soft and sliced easily by a scalpel blade.
In order to make valid comparisons between mouldings before and after treatment, it was vitally important to ensure that the scalpel cuts passed precisely through the same regions, so that the cross-section being compared were taken at the same point in all cases. The cutting was performed with scrutiny by a low-power (x20 magnification) stereo microscope.
The cut edges were photographed (see figures 2. 3. and 9. 10) using a 35mm single- lens reflex camera fitted with close-up lens attachments. A scale marked with 1 mm divisions is shown on all such views to provide an indication of the dimension of the surface topography of each cast.
Example 1
A first subject being a male aged 45 was treated by taking a first cast from the skin area around the left and right eyes. The cast impression of around the left eye is shown in plan in figure 1. The cast around the right eye was sliced to enable the mould profile to be inspected and the result is shown in the top cast section of the photograph shown in figure 2. The significant creases represented by peaks in the cast section are marked with the letters A to F. A scale with 1mm divisions is shown at the bottom of the photograph. The top cast section in the photograph of figure 3 shows an angled view of the same cast with the peaks labelled in the same manner as in figure 2.
After removal of the first cast, the area of skin around the left and right eyes of the first subject was then exposed to orange light of wavelength 585-650 nano metres for a period of twenty minutes followed by exposure to yellow light of wavelength 575-585 nano metres for a period of six minutes.
After this treatment second casts of the skin around the left and right eyes were immediately taken and a plan view of the left eye cast is shown in figure 2. The cast from the right eye was sliced and an end view is shown on the middle cast in the photograph of figure 4. an angle view being shown in the middle cast of figure 5. It will be seen from the photographs that peaks A and C have virtually disappeared whereas peaks B. E and F are significantly reduced in height.
A period of sixteen days passed during which collagen skin food was applied daily to the skin around the eyes of the subject. On the seventeenth day the light exposure treatment of the present invention was repeated and casts were again taken. The results are shown in figure 3 (left eye) and the bottom casts in the photographs of figures 4 and 5 (right eye). It will be seen, in the case of the right eye. that creases A. C. E and F have practically disappeared, whereas crease B is significantly reduced in height. Crease D in figures 4 and 5 is obscured by a bubble in the mould material. It will also be apparent from comparison of the three casts of each of the left and right eye that the skin surface and texture is smoother generally. Example 2
Subject two was a female aged 51 . She was subjected to the same treatment as described in Example 1. The results for the skin area around the left eye are shown in figures 6 to 10. Figures 6 to 8 show in plan the casts taken respective before treatment, after the first treatment and after the second treatment sixteen days later. It will be seen that the number, height and length of each crease has been reduced dramatically. After the second treatment it will be seen that only five elevations in the cast remain and all these are reduced in height and length.
Figures 9 and 10 show sections through the casts before treatment (top) and after the second treatment (bottom). Again a 1mm scale is shown at the bottom of figure 9 and the middle of figure 10. Selected main elevations in the cast (representing lines in the skin) before treatment have been identified with the letters A to H. It will be seen that after treatment (bottom cast in each figure) only elevation F remains prominent at the cross- section. Elevations A. B. D. E. G and H are significantly diminished whereas C (perhaps the largest elevation before treatment) has disappeared completely. Again it will be apparent from figures 8 and 10 that the general surface texture of the skin is significantly smoother.
Example 3
Figures 1 1 to 13 show, respectively, castings taken from around the left eye of a third subject: a female aged 60. It will be seen that the number, height and length of each elevation has been reduced dramatically leaving only few elevations that are just visible without magnification.

Claims

1. A method of cosmetic treatment of skin lines comprising the steps of exposing the area to be treated to orange light of wavelength in the range 585-560 nano metres and frequency 460-510 x 10 " hertz for a period in the range 15 to 25 minutes, followed by yellow light
I of wavelength 575-585 nano metres and frequency 510-520 x 10 " hertz for a period in the range 4 to 6 minutes.
2. A method of cosmetic treatment of skin lines according to claim 1. wherein the skin to be treated is initially covered with collagen skin food prior to light being directed thereat.
3. A method of cosmetic treatment of skin lines according to claim 1 or 2. wherein the area to be treated is exposed to the orange light for 20 minutes.
4. A method of cosmetic treatment of skin lines according to claims 1.2 or 3. wherein the area to be treated is exposed to yellow light for 5 minutes.
5. A method of cosmetic treatment of skin lines according to any preceding claim, wherein the light is emitted form a source being a 50 Watt halogen lamp.
6. A method of cosmetic treatment of skin lines according to any preceding claim, wherein the light source is positioned at a distance of 15 centimetres from the area to be treated.
7. A method of cosmetic treatment of skin lines substantially as hereinbefore described.
PCT/GB1996/001003 1995-04-26 1996-04-26 Improvements in or relating to cosmetic treatment of skin lines WO1996033773A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU54059/96A AU5405996A (en) 1995-04-26 1996-04-26 Improvements in or relating to cosmetic treatment of skin li nes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9508499.2A GB9508499D0 (en) 1995-04-26 1995-04-26 Improvements in or relating to cosmetic treatment of skin lines
GB9508499.2 1995-04-26

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WO1996033773A2 true WO1996033773A2 (en) 1996-10-31
WO1996033773A3 WO1996033773A3 (en) 1996-12-27

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GB (1) GB9508499D0 (en)
WO (1) WO1996033773A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998008568A1 (en) * 1996-08-29 1998-03-05 Sls Biophile Limited Wrinkle removal
GB2336545A (en) * 1998-04-21 1999-10-27 Oe Lys Limited Skin treatment
GB2368020A (en) * 2000-10-18 2002-04-24 Icn Photonics Ltd Treatment of acne vulgaris skin condition by irradiation with light of specific wavelengths to target specific chromophores & stimulate collagen production

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0026239A1 (en) * 1979-09-29 1981-04-08 Detlef Köppen Medical and cosmetic irradiation apparatus
FR2582523A1 (en) * 1985-05-31 1986-12-05 Cancoin Isabelle Chromo-lumino-thermal device for cosmetic and relaxation treatment
WO1992018200A1 (en) * 1991-04-11 1992-10-29 Christian Schmid Method of generating light for colour therapy
DE4127564A1 (en) * 1991-08-21 1993-04-08 Peter Hennig Coloured light processor to give full colour spectrum from IR to UV light - has monochromatic colour filter with wavelength shift from 350 nm to 75 nm and output light can be conducted across glass fibre optic and can transmit cold light
US5259380A (en) * 1987-11-04 1993-11-09 Amcor Electronics, Ltd. Light therapy system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0026239A1 (en) * 1979-09-29 1981-04-08 Detlef Köppen Medical and cosmetic irradiation apparatus
FR2582523A1 (en) * 1985-05-31 1986-12-05 Cancoin Isabelle Chromo-lumino-thermal device for cosmetic and relaxation treatment
US5259380A (en) * 1987-11-04 1993-11-09 Amcor Electronics, Ltd. Light therapy system
WO1992018200A1 (en) * 1991-04-11 1992-10-29 Christian Schmid Method of generating light for colour therapy
DE4127564A1 (en) * 1991-08-21 1993-04-08 Peter Hennig Coloured light processor to give full colour spectrum from IR to UV light - has monochromatic colour filter with wavelength shift from 350 nm to 75 nm and output light can be conducted across glass fibre optic and can transmit cold light

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WILSON: "The physics of photodynamic therapy" 1986 , PHYSICS IN MEDICINE & BIOLOGY , LONDON,GREAT-BRITAIN XP002018138 31 see the whole document *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998008568A1 (en) * 1996-08-29 1998-03-05 Sls Biophile Limited Wrinkle removal
GB2336545A (en) * 1998-04-21 1999-10-27 Oe Lys Limited Skin treatment
GB2368020A (en) * 2000-10-18 2002-04-24 Icn Photonics Ltd Treatment of acne vulgaris skin condition by irradiation with light of specific wavelengths to target specific chromophores & stimulate collagen production
WO2002032505A1 (en) * 2000-10-18 2002-04-25 Icn Photonics Limited Illumination radiation treatment of skin conditions

Also Published As

Publication number Publication date
WO1996033773A3 (en) 1996-12-27
GB9508499D0 (en) 1995-06-14
AU5405996A (en) 1996-11-18

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