WO1996032198A1 - Centrifuged system for intermittent collection of mononuclear cells - Google Patents
Centrifuged system for intermittent collection of mononuclear cells Download PDFInfo
- Publication number
- WO1996032198A1 WO1996032198A1 PCT/US1996/005144 US9605144W WO9632198A1 WO 1996032198 A1 WO1996032198 A1 WO 1996032198A1 US 9605144 W US9605144 W US 9605144W WO 9632198 A1 WO9632198 A1 WO 9632198A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- component
- barrier
- collect
- liquid
- essentially
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
- B04B2005/045—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation having annular separation channels
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69605901T DE69605901T2 (en) | 1995-04-14 | 1996-04-12 | CENTRIFUGING SYSTEM FOR INTERMITTENT COLLECTION OF MONONUCLEAR CELLS |
EP96911756A EP0817680B1 (en) | 1995-04-14 | 1996-04-12 | Centrifuged system for intermittent collection of mononuclear cells |
JP53124696A JP4580470B2 (en) | 1995-04-14 | 1996-04-12 | Intermittent collection of mononuclear cells |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/422,597 US5704888A (en) | 1995-04-14 | 1995-04-14 | Intermittent collection of mononuclear cells in a centrifuge apparatus |
US08/422,597 | 1995-04-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1996032198A1 true WO1996032198A1 (en) | 1996-10-17 |
Family
ID=23675570
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1996/005144 WO1996032198A1 (en) | 1995-04-14 | 1996-04-12 | Centrifuged system for intermittent collection of mononuclear cells |
Country Status (5)
Country | Link |
---|---|
US (2) | US5704888A (en) |
EP (1) | EP0817680B1 (en) |
JP (1) | JP4580470B2 (en) |
DE (1) | DE69605901T2 (en) |
WO (1) | WO1996032198A1 (en) |
Cited By (8)
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---|---|---|---|---|
US5750039A (en) * | 1987-01-30 | 1998-05-12 | Baxter International Inc. | Blood processing systems and methods for collecting mono nuclear cells |
US5961842A (en) * | 1995-06-07 | 1999-10-05 | Baxter International Inc. | Systems and methods for collecting mononuclear cells employing control of packed red blood cell hematocrit |
US5980760A (en) * | 1997-07-01 | 1999-11-09 | Baxter International Inc. | System and methods for harvesting mononuclear cells by recirculation of packed red blood cells |
US6027657A (en) * | 1997-07-01 | 2000-02-22 | Baxter International Inc. | Systems and methods for collecting diluted mononuclear cells |
WO2000054886A1 (en) * | 1999-03-16 | 2000-09-21 | Gambro,Inc | Centrifugal separation apparatus and method for separating fluid components |
US6582349B1 (en) | 1997-07-01 | 2003-06-24 | Baxter International Inc. | Blood processing system |
DE10306534B4 (en) * | 2002-02-17 | 2012-04-12 | Schober Meditec Gmbh | Device for increasing the catalytic activity of enzymes by emission of induction and light signals |
CN107413536A (en) * | 2012-02-15 | 2017-12-01 | 肯西纳什公司 | Centrifuge |
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US6294094B1 (en) | 1999-09-03 | 2001-09-25 | Baxter International Inc. | Systems and methods for sensing red blood cell hematocrit |
US6284142B1 (en) * | 1999-09-03 | 2001-09-04 | Baxter International Inc. | Sensing systems and methods for differentiating between different cellular blood species during extracorporeal blood separation or processing |
US6348156B1 (en) | 1999-09-03 | 2002-02-19 | Baxter International Inc. | Blood processing systems and methods with sensors to detect contamination due to presence of cellular components or dilution due to presence of plasma |
US6524231B1 (en) * | 1999-09-03 | 2003-02-25 | Baxter International Inc. | Blood separation chamber with constricted interior channel and recessed passage |
US7011761B2 (en) * | 1999-09-03 | 2006-03-14 | Baxter International Inc. | Red blood cell processing systems and methods which control red blood cell hematocrit |
US7947236B2 (en) | 1999-12-03 | 2011-05-24 | Becton, Dickinson And Company | Device for separating components of a fluid sample |
US6354986B1 (en) | 2000-02-16 | 2002-03-12 | Gambro, Inc. | Reverse-flow chamber purging during centrifugal separation |
JP4382322B2 (en) * | 2000-03-09 | 2009-12-09 | カリディアンビーシーティ、インコーポレイテッド | Extracorporeal blood treatment equipment |
WO2002062482A2 (en) | 2000-11-02 | 2002-08-15 | Gambro, Inc. | Fluid separation devices, systems and methods |
JP2004536794A (en) * | 2001-04-09 | 2004-12-09 | メドトロニック、インコーポレイテッド | Method for separating blood components using microcentrifuge and method for using the same |
US6579219B2 (en) * | 2001-04-09 | 2003-06-17 | Medtronic, Inc. | Centrifuge bag and methods of use |
US6890291B2 (en) * | 2001-06-25 | 2005-05-10 | Mission Medical, Inc. | Integrated automatic blood collection and processing unit |
US6878105B2 (en) * | 2001-08-16 | 2005-04-12 | Baxter International Inc. | Red blood cell processing systems and methods with deliberate under spill of red blood cells |
US20030173274A1 (en) * | 2002-02-01 | 2003-09-18 | Frank Corbin | Blood component separation device, system, and method including filtration |
CA2642653A1 (en) | 2002-04-16 | 2003-10-30 | Gambro Bct, Inc. | Blood component processing system, apparatus and method |
EP1497645A2 (en) | 2002-04-19 | 2005-01-19 | Mission Medical, Inc. | Integrated automatic blood processing unit |
US7297272B2 (en) * | 2002-10-24 | 2007-11-20 | Fenwal, Inc. | Separation apparatus and method |
US7354515B2 (en) | 2004-02-23 | 2008-04-08 | Millennium Medical Technologies, Inc. | Fluid concentrator |
US7087177B2 (en) * | 2004-04-16 | 2006-08-08 | Baxter International Inc. | Methods for determining flow rates of biological fluids |
US20060226086A1 (en) * | 2005-04-08 | 2006-10-12 | Robinson Thomas C | Centrifuge for blood processing systems |
US8685258B2 (en) * | 2008-02-27 | 2014-04-01 | Fenwal, Inc. | Systems and methods for conveying multiple blood components to a recipient |
US8075468B2 (en) * | 2008-02-27 | 2011-12-13 | Fenwal, Inc. | Systems and methods for mid-processing calculation of blood composition |
JP5607621B2 (en) | 2008-07-21 | 2014-10-15 | ベクトン・ディキンソン・アンド・カンパニー | Density phase separation device |
CA2731155C (en) | 2008-07-21 | 2013-09-24 | Becton, Dickinson And Company | Density phase separation device |
ES2548183T3 (en) | 2008-07-21 | 2015-10-14 | Becton Dickinson And Company | Density phase separation device |
PL2429708T3 (en) | 2009-05-15 | 2021-06-14 | Becton, Dickinson And Company | Density phase separation device |
US9011684B2 (en) | 2011-03-07 | 2015-04-21 | Spinesmith Holdings, Llc | Fluid concentrator with removable cartridge |
CA2855640C (en) | 2011-11-14 | 2020-03-10 | The General Hospital Corporation | Assays and methods for selecting a treatment regimen for a subject with depression |
EP2664383A1 (en) * | 2012-05-15 | 2013-11-20 | Miltenyi Biotec GmbH | Centrifugation chamber with deflector shields |
US9248446B2 (en) | 2013-02-18 | 2016-02-02 | Terumo Bct, Inc. | System for blood separation with a separation chamber having an internal gravity valve |
US20150017714A1 (en) | 2013-07-02 | 2015-01-15 | Miltenyi Biotec Gmbh | Centrifugation chamber with gas permeable membrane layers for cell cultivation |
EP2821144A1 (en) * | 2013-07-02 | 2015-01-07 | Miltenyi Biotec GmbH | Centrifugation chamber with gas-permeable membrane for cell cultivation |
EP2821145B1 (en) * | 2013-07-02 | 2019-08-21 | Miltenyi Biotec GmbH | Centrifugation chamber with gas-permeable membranes layers for cell cultivation |
US9694359B2 (en) | 2014-11-13 | 2017-07-04 | Becton, Dickinson And Company | Mechanical separator for a biological fluid |
US9833557B2 (en) | 2014-12-19 | 2017-12-05 | Fenwal, Inc. | Systems and methods for determining free plasma hemoglobin |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3655123A (en) * | 1966-08-08 | 1972-04-11 | Us Health Education & Welfare | Continuous flow blood separator |
US4094461A (en) * | 1977-06-27 | 1978-06-13 | International Business Machines Corporation | Centrifuge collecting chamber |
US4356958A (en) * | 1977-07-19 | 1982-11-02 | The United States Of America As Represented By The Secretary Of Health And Human Services | Blood cell separator |
US4647279A (en) * | 1985-10-18 | 1987-03-03 | Cobe Laboratories, Inc. | Centrifugal separator |
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US1723212A (en) * | 1925-11-30 | 1929-08-06 | Fostoria Serum Company | Process of clarifying liquids |
US3452924A (en) * | 1965-02-03 | 1969-07-01 | Sorvall Inc Ivan | System and method for washing blood and the like |
BE754683A (en) * | 1969-08-11 | 1971-01-18 | Aga Ab | CONTAINER INTENDED TO CONTAIN BLOOD |
US3724747A (en) * | 1971-03-15 | 1973-04-03 | Aga Ab | Centrifuge apparatus with means for moving material |
US3737096A (en) * | 1971-12-23 | 1973-06-05 | Ibm | Blood processing control apparatus |
US4934995A (en) * | 1977-08-12 | 1990-06-19 | Baxter International Inc. | Blood component centrifuge having collapsible inner liner |
US3858795A (en) * | 1973-02-08 | 1975-01-07 | Int Equipment Co | Method for washing blood cells |
US4007871A (en) * | 1975-11-13 | 1977-02-15 | International Business Machines Corporation | Centrifuge fluid container |
US4010894A (en) * | 1975-11-21 | 1977-03-08 | International Business Machines Corporation | Centrifuge fluid container |
US4636193A (en) * | 1976-05-14 | 1987-01-13 | Baxter Travenol Laboratories, Inc. | Disposable centrifugal blood processing system |
US4091989A (en) * | 1977-01-04 | 1978-05-30 | Schlutz Charles A | Continuous flow fractionation and separation device and method |
US4120844A (en) * | 1977-03-09 | 1978-10-17 | Ford Motor Company | Molded calcium carbonate filled propylene resin composites |
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US5006103A (en) * | 1977-08-12 | 1991-04-09 | Baxter International Inc. | Disposable container for a centrifuge |
US4387848A (en) * | 1977-10-03 | 1983-06-14 | International Business Machines Corporation | Centrifuge assembly |
US4151844A (en) * | 1977-11-11 | 1979-05-01 | Baxter Travenol Laboratories, Inc. | Method and apparatus for separating whole blood into its components and for automatically collecting one component |
US4386730A (en) * | 1978-07-21 | 1983-06-07 | International Business Machines Corporation | Centrifuge assembly |
US4187979A (en) * | 1978-09-21 | 1980-02-12 | Baxter Travenol Laboratories, Inc. | Method and system for fractionating a quantity of blood into the components thereof |
DE2948177A1 (en) * | 1979-11-30 | 1981-06-04 | Dr. Eduard Fresenius Chemisch-Pharmazeutische Industrie Kg Apparatebau Kg, 6380 Bad Homburg | SEPARATOR FOR ULTRA CENTRIFUGE |
US4316576A (en) * | 1980-11-06 | 1982-02-23 | Baxter Travenol Laboratories, Inc. | Method and chamber for separating granulocytes from whole blood |
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DE3301113C2 (en) * | 1983-01-14 | 1985-01-10 | Fresenius AG, 6380 Bad Homburg | Method and device for separating media |
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-
1995
- 1995-04-14 US US08/422,597 patent/US5704888A/en not_active Expired - Lifetime
-
1996
- 1996-04-12 DE DE69605901T patent/DE69605901T2/en not_active Expired - Lifetime
- 1996-04-12 JP JP53124696A patent/JP4580470B2/en not_active Expired - Fee Related
- 1996-04-12 WO PCT/US1996/005144 patent/WO1996032198A1/en active IP Right Grant
- 1996-04-12 EP EP96911756A patent/EP0817680B1/en not_active Expired - Lifetime
-
1997
- 1997-06-09 US US08/871,207 patent/US5879280A/en not_active Expired - Lifetime
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3655123A (en) * | 1966-08-08 | 1972-04-11 | Us Health Education & Welfare | Continuous flow blood separator |
US4094461A (en) * | 1977-06-27 | 1978-06-13 | International Business Machines Corporation | Centrifuge collecting chamber |
US4356958A (en) * | 1977-07-19 | 1982-11-02 | The United States Of America As Represented By The Secretary Of Health And Human Services | Blood cell separator |
US4647279A (en) * | 1985-10-18 | 1987-03-03 | Cobe Laboratories, Inc. | Centrifugal separator |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750039A (en) * | 1987-01-30 | 1998-05-12 | Baxter International Inc. | Blood processing systems and methods for collecting mono nuclear cells |
US5807492A (en) * | 1987-01-30 | 1998-09-15 | Baxter International Inc. | Blood processing systems and methods for collecting mono nuclear cell |
US5961842A (en) * | 1995-06-07 | 1999-10-05 | Baxter International Inc. | Systems and methods for collecting mononuclear cells employing control of packed red blood cell hematocrit |
US5980760A (en) * | 1997-07-01 | 1999-11-09 | Baxter International Inc. | System and methods for harvesting mononuclear cells by recirculation of packed red blood cells |
US6027657A (en) * | 1997-07-01 | 2000-02-22 | Baxter International Inc. | Systems and methods for collecting diluted mononuclear cells |
US6582349B1 (en) | 1997-07-01 | 2003-06-24 | Baxter International Inc. | Blood processing system |
WO2000054886A1 (en) * | 1999-03-16 | 2000-09-21 | Gambro,Inc | Centrifugal separation apparatus and method for separating fluid components |
DE10306534B4 (en) * | 2002-02-17 | 2012-04-12 | Schober Meditec Gmbh | Device for increasing the catalytic activity of enzymes by emission of induction and light signals |
CN107413536A (en) * | 2012-02-15 | 2017-12-01 | 肯西纳什公司 | Centrifuge |
CN107413536B (en) * | 2012-02-15 | 2019-09-06 | 帝斯曼知识产权资产管理有限公司 | Centrifuge |
Also Published As
Publication number | Publication date |
---|---|
JPH11503664A (en) | 1999-03-30 |
JP4580470B2 (en) | 2010-11-10 |
EP0817680B1 (en) | 1999-12-29 |
US5879280A (en) | 1999-03-09 |
DE69605901T2 (en) | 2000-05-04 |
EP0817680A1 (en) | 1998-01-14 |
US5704888A (en) | 1998-01-06 |
DE69605901D1 (en) | 2000-02-03 |
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