WO1996020287A3 - Detection of nucleic acids by target-catalyzed product formation - Google Patents
Detection of nucleic acids by target-catalyzed product formation Download PDFInfo
- Publication number
- WO1996020287A3 WO1996020287A3 PCT/US1995/016771 US9516771W WO9620287A3 WO 1996020287 A3 WO1996020287 A3 WO 1996020287A3 US 9516771 W US9516771 W US 9516771W WO 9620287 A3 WO9620287 A3 WO 9620287A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fragment
- polynucleotide analyte
- detection
- oligonucleotide
- polynucleotide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69528670T DE69528670T2 (en) | 1994-12-23 | 1995-12-22 | DETECTION OF NUCLEIC ACIDS BY NUCLEASE-CATALYZED PRODUCT PRODUCTION |
EP95944648A EP0842294B1 (en) | 1994-12-23 | 1995-12-22 | Detection of nucleic acids by nuclease-catalyzed product formation |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36316994A | 1994-12-23 | 1994-12-23 | |
US08/363,169 | 1994-12-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1996020287A2 WO1996020287A2 (en) | 1996-07-04 |
WO1996020287A3 true WO1996020287A3 (en) | 1996-09-06 |
Family
ID=23429108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1995/016771 WO1996020287A2 (en) | 1994-12-23 | 1995-12-22 | Detection of nucleic acids by target-catalyzed product formation |
Country Status (5)
Country | Link |
---|---|
US (7) | US5792614A (en) |
EP (2) | EP1260593A3 (en) |
DE (1) | DE69528670T2 (en) |
ES (1) | ES2185719T3 (en) |
WO (1) | WO1996020287A2 (en) |
Families Citing this family (103)
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US6875572B2 (en) | 1996-01-24 | 2005-04-05 | Third Wave Technologies, Inc. | Nucleic acid detection assays |
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US5985557A (en) | 1996-01-24 | 1999-11-16 | Third Wave Technologies, Inc. | Invasive cleavage of nucleic acids |
US6090606A (en) * | 1996-01-24 | 2000-07-18 | Third Wave Technologies, Inc. | Cleavage agents |
US7122364B1 (en) * | 1998-03-24 | 2006-10-17 | Third Wave Technologies, Inc. | FEN endonucleases |
US6562611B1 (en) | 1996-11-29 | 2003-05-13 | Third Wave Technologies, Ins. | FEN-1 endonucleases, mixtures and cleavage methods |
US20080160524A1 (en) * | 1996-01-24 | 2008-07-03 | Third Wave Technologies, Inc. | Methods and Compositions for Detecting Target Sequences |
US6706471B1 (en) | 1996-01-24 | 2004-03-16 | Third Wave Technologies, Inc. | Detection of nucleic acid sequences by invader-directed cleavage |
US7195871B2 (en) | 1996-01-24 | 2007-03-27 | Third Wave Technologies, Inc | Methods and compositions for detecting target sequences |
US6780982B2 (en) * | 1996-07-12 | 2004-08-24 | Third Wave Technologies, Inc. | Charge tags and the separation of nucleic acid molecules |
US6503709B1 (en) | 1997-07-03 | 2003-01-07 | Id Biomedical Corporation | Methods for rapidly detecting methicillin resistant staphylococci |
US8182991B1 (en) | 1997-11-26 | 2012-05-22 | Third Wave Technologies, Inc. | FEN-1 endonucleases, mixtures and cleavage methods |
US6187566B1 (en) | 1999-03-09 | 2001-02-13 | Applied Gene Technologies, Inc. | Method of labeling a nucleic acid amplicon with simultaneous contamination prevention |
US6514700B1 (en) * | 1999-04-30 | 2003-02-04 | Aclara Biosciences, Inc. | Nucleic acid detection using degradation of a tagged sequence |
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Citations (6)
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WO1989009284A1 (en) * | 1988-03-24 | 1989-10-05 | University Of Iowa Research Foundation | Catalytic hybridization systems for the detection of nucleic acid sequences based on their activity as cofactors in catalytic reactions in which a complementary labeled nucleic acid probe is cleaved |
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EP0601834A1 (en) * | 1992-12-07 | 1994-06-15 | Wisconsin Alumni Research Foundation | Method of cleaving a nucleic acid molecule |
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-
1995
- 1995-12-22 EP EP02008466A patent/EP1260593A3/en not_active Withdrawn
- 1995-12-22 ES ES95944648T patent/ES2185719T3/en not_active Expired - Lifetime
- 1995-12-22 EP EP95944648A patent/EP0842294B1/en not_active Expired - Lifetime
- 1995-12-22 WO PCT/US1995/016771 patent/WO1996020287A2/en active IP Right Grant
- 1995-12-22 DE DE69528670T patent/DE69528670T2/en not_active Expired - Lifetime
-
1996
- 1996-08-02 US US08/691,627 patent/US5792614A/en not_active Expired - Lifetime
-
1998
- 1998-01-30 US US09/015,949 patent/US6110677A/en not_active Expired - Lifetime
-
1999
- 1999-11-15 US US09/440,363 patent/US6121001A/en not_active Expired - Lifetime
-
2000
- 2000-06-30 US US09/608,721 patent/US6368803B1/en not_active Expired - Fee Related
-
2001
- 2001-11-20 US US09/989,757 patent/US20020155548A1/en not_active Abandoned
-
2005
- 2005-02-09 US US11/054,255 patent/US20050191676A1/en not_active Abandoned
-
2007
- 2007-10-09 US US11/869,054 patent/US20080213767A1/en not_active Abandoned
Patent Citations (6)
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WO1989009284A1 (en) * | 1988-03-24 | 1989-10-05 | University Of Iowa Research Foundation | Catalytic hybridization systems for the detection of nucleic acid sequences based on their activity as cofactors in catalytic reactions in which a complementary labeled nucleic acid probe is cleaved |
WO1989010415A1 (en) * | 1988-04-29 | 1989-11-02 | Meiogenics, Inc. | Methods for detecting nucleic acid sequences |
WO1991017264A1 (en) * | 1990-05-02 | 1991-11-14 | Imperial Chemical Industries Plc | Assay for specific nucleic acid sequences |
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EP0601834A1 (en) * | 1992-12-07 | 1994-06-15 | Wisconsin Alumni Research Foundation | Method of cleaving a nucleic acid molecule |
Also Published As
Publication number | Publication date |
---|---|
DE69528670T2 (en) | 2004-03-11 |
ES2185719T3 (en) | 2003-05-01 |
EP1260593A3 (en) | 2003-12-03 |
US20050191676A1 (en) | 2005-09-01 |
EP0842294B1 (en) | 2002-10-23 |
EP1260593A2 (en) | 2002-11-27 |
WO1996020287A2 (en) | 1996-07-04 |
US5792614A (en) | 1998-08-11 |
US20020155548A1 (en) | 2002-10-24 |
EP0842294A2 (en) | 1998-05-20 |
US6121001A (en) | 2000-09-19 |
US20080213767A1 (en) | 2008-09-04 |
DE69528670D1 (en) | 2002-11-28 |
US6368803B1 (en) | 2002-04-09 |
US6110677A (en) | 2000-08-29 |
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