WO1996008999A1 - Use of implant with magnetic properties to determine the position of a patient - Google Patents
Use of implant with magnetic properties to determine the position of a patient Download PDFInfo
- Publication number
- WO1996008999A1 WO1996008999A1 PCT/SE1995/001082 SE9501082W WO9608999A1 WO 1996008999 A1 WO1996008999 A1 WO 1996008999A1 SE 9501082 W SE9501082 W SE 9501082W WO 9608999 A1 WO9608999 A1 WO 9608999A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- patient
- implant
- relation
- magnetic
- magnetic field
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
- A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
- A61B5/062—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body using magnetic field
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3954—Markers, e.g. radio-opaque or breast lesions markers magnetic, e.g. NMR or MRI
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
- A61B5/4504—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
- A61N2005/1051—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using an active marker
Definitions
- the present invention relates to the determination of the position of special points or areas on or in live creatures.
- live creatures relates to both humans and animals and they will in the following specification and claims, for simplicity reasons, jointly be called "patients”.
- treatment In medicine it is common to make diagnoses, perform other investigations and treat patients by means of external equipments such as x-ray apparatuses, radiation treatment apparatuses and other types of apparatuses. For simplicity reasons such external diagnosis, other investigation or treatment will in the following jointly be referred to as "treatment". In many cases it is necessary to be able to reproduce the position of the patient in relation to the external equipment as accurately as possible in all space dimensions from one treatment to another. This is in particular true when the treatment might cause damages on surrounding organs, tissue etc., like in, for example, the case with radiation treatment.
- the presently most common method for determining the position of a patient in relation to the external treatment-equipment from one treatment to another is to make markings on the skin of the patient, for example in the form of "crosses" or the like.
- This procedure is not very reliable since the skin moves in relation to the internal organs, tissues, etc. which are to be treated. There is, therefore, a great chance that the treatment, in particular if it is radiation treatment, damages healthy internal organs, tissues, etc. in the patient. There is therefore a great need of being able to accurately and in a reproducable manner be able to align a patient in relation to the external equipment from one treat ⁇ ment to another.
- US-A-5, 125,888 discloses a method for transporting, by means of an electromagnetic field, a drug with attached magnetic object to a desired location in the body, especially the brain, for administration of the drug to that spot, and retraction of the magnetic object.
- SU-A-1,338,154 discloses a method of matching the radiation parameters in proton therapy, wherin detectors interrupt the treatment if permitted radiation parameters are exceeded.
- FI,B, 79458 discloses a method and a device for eliminating errors which are caused by the patient's movements in a treatment situation, wherein a mark is made on the skin in the very treatment area. The momentaneous position of this mark is followed by continuously determining the position coordinates of the mark, and treatment is started when the position coordinates of the mark correspond to pre-determined comparison coordinates.
- WO, Al, 93/00039 discloses a device for detecting and localizing, by means of an electomagnetic field, a metallic object which has been penetrated or implanted into a human or animal body.
- the reference numeral 1 shows a magnetic implant which e.g. may be an implanted permanent magnet. It is, however, within the scope of the invention possible to choose an arbitrary implant having the ability to produce, as such or in combination with any other material, produce detectable magnetic fields (including electromagnetic fields) and/or changes of magnetic fields, etc.
- the implant 1 is attached to a suitable body part 2 which, in contrast to the skin, has a comparatively constant position in the body.
- the body part is a bone in the body.
- Reference numeral 3 represents the skin of the patient. It is preferred to position the implant as close as possible to the respective area of treatment, but outside the same.
- the implant can also often be suitable to encapsulate the implant in a more tissue-friendly material.
- the implant is also preferably provided with devices and/or materials which are known per se and makes an accurate securing of the implant in bones possible, for example screws, plates, orthopedical supports and the like.
- the implant can be an "explant", i.e. be located in a corresponding position outside the body, preferably in the vicinity of, and positionally connected to, underneath parts, e.g. a bone.
- the schematically shown device 4 which is located outside the patient, represents one or more sensors detecting magnetic fields and/or changes of magnetic fields, e.g. from the implant 1 and/or another device cooperating therewith.
- the implant does not have to be magnetic as such, but is capable of acting by induction, it will be possible to use e.g. magnetically insensitive spools of copper which do not interfere with investigations using magnetic resonanse tomography. Since the position of the sensor 4 is known, the position of the im- plant/explant 1 can be calculated in a simple manner. Since the position of the implant in the patient is known, as is also its relation to the target of the treatment such as a radiation target, it is also possible to determine the positions for the patient and the target of the treatment. The design of the sensors 4 can be varied as needed in the individual case, from a simple spool to more advanced elements which are sensitive to magnetic fields, e.g.
- FIG. 1 shows a sensor 4 built-up from 25 analogous Hall sensors which are arranged in 5 rows of 5 sensors each. By reading the signals from the sensors into a computer 6, using an analogue-to-digital converter 5, each sensor can be read rapidly.
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95933014A EP0955879A1 (en) | 1994-09-22 | 1995-09-22 | Use of implant with magnetic properties to determine the position of a patient |
JP8510822A JPH10505776A (en) | 1994-09-22 | 1995-09-22 | Use of magnetic implants to locate patients |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9403193-7 | 1994-09-22 | ||
SE9403193A SE9403193L (en) | 1994-09-22 | 1994-09-22 | Method and device for position determination |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1996008999A1 true WO1996008999A1 (en) | 1996-03-28 |
Family
ID=20395339
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/SE1995/001082 WO1996008999A1 (en) | 1994-09-22 | 1995-09-22 | Use of implant with magnetic properties to determine the position of a patient |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0955879A1 (en) |
JP (1) | JPH10505776A (en) |
SE (1) | SE9403193L (en) |
WO (1) | WO1996008999A1 (en) |
Cited By (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998049938A1 (en) * | 1997-05-08 | 1998-11-12 | Lucent Medical Systems, Inc. | System and method to determine the location and orientation of an indwelling medical device |
WO1998052466A1 (en) * | 1997-05-21 | 1998-11-26 | Lucent Medical Systems, Inc. | Non-invasive sensing of a physical parameter |
WO2000051514A1 (en) * | 1999-03-01 | 2000-09-08 | Lucent Medical Systems, Inc. | Magnetic anatomical marker and method of use |
US6129668A (en) * | 1997-05-08 | 2000-10-10 | Lucent Medical Systems, Inc. | System and method to determine the location and orientation of an indwelling medical device |
US6263230B1 (en) | 1997-05-08 | 2001-07-17 | Lucent Medical Systems, Inc. | System and method to determine the location and orientation of an indwelling medical device |
WO2002100485A1 (en) * | 2001-06-08 | 2002-12-19 | Calypso Medical Technologies, Inc. | Guided radiation therapy system |
WO2003011394A1 (en) * | 2001-07-27 | 2003-02-13 | Bhc Engineering, Lp | Method and device for monitoring real-time position of an area targeted by a radiosurgery system |
US6675810B2 (en) | 1998-05-14 | 2004-01-13 | Calypso Medical Technologies, Inc. | System and method for bracketing and removing tissue |
WO2004030536A1 (en) * | 2002-10-01 | 2004-04-15 | Potencia Medical Ag | Detection of implanted injection port |
US6812842B2 (en) | 2001-12-20 | 2004-11-02 | Calypso Medical Technologies, Inc. | System for excitation of a leadless miniature marker |
US6822570B2 (en) | 2001-12-20 | 2004-11-23 | Calypso Medical Technologies, Inc. | System for spatially adjustable excitation of leadless miniature marker |
US6838990B2 (en) | 2001-12-20 | 2005-01-04 | Calypso Medical Technologies, Inc. | System for excitation leadless miniature marker |
US6889833B2 (en) | 2002-12-30 | 2005-05-10 | Calypso Medical Technologies, Inc. | Packaged systems for implanting markers in a patient and methods for manufacturing and using such systems |
WO2006077200A1 (en) * | 2005-01-18 | 2006-07-27 | Charité - Universitätsmedizin Berlin | Endoscopic marking agent, instruments for applying and detecting the marking agent and for operatively fixing the marked tissue area |
EP1803413A3 (en) * | 2005-12-30 | 2008-08-13 | DePuy Products, Inc. | Magnetic sensor array for bone registration in computer-assisted orthopaedic surgery |
AU2006252293B2 (en) * | 2005-12-30 | 2011-10-13 | Depuy Products, Inc. | System and method for registering a bone of a patient with a computer assisted orthopaedic surgery system |
US8068648B2 (en) | 2006-12-21 | 2011-11-29 | Depuy Products, Inc. | Method and system for registering a bone of a patient with a computer assisted orthopaedic surgery system |
US8862200B2 (en) | 2005-12-30 | 2014-10-14 | DePuy Synthes Products, LLC | Method for determining a position of a magnetic source |
US8857043B2 (en) | 2002-12-30 | 2014-10-14 | Varian Medical Systems, Inc. | Method of manufacturing an implantable marker with a leadless signal transmitter |
US9237860B2 (en) | 2008-06-05 | 2016-01-19 | Varian Medical Systems, Inc. | Motion compensation for medical imaging and associated systems and methods |
US9616248B2 (en) | 2002-06-05 | 2017-04-11 | Varian Medical Systems, Inc. | Integrated radiation therapy systems and methods for treating a target in a patient |
US9764160B2 (en) | 2011-12-27 | 2017-09-19 | HJ Laboratories, LLC | Reducing absorption of radiation by healthy cells from an external radiation source |
WO2023020241A1 (en) * | 2021-08-16 | 2023-02-23 | The University Of Hong Kong | Non-contact, non-radiation device that accurately locates multiple implants in patient's body |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4445501A (en) * | 1981-05-07 | 1984-05-01 | Mccormick Laboratories, Inc. | Circuits for determining very accurately the position of a device inside biological tissue |
FI79458B (en) * | 1986-04-16 | 1989-09-29 | Seppo Peltola | OVER ANCHORING FOER STYRNING AV EN BEHANDLINGSANORDNING. |
US4943770A (en) * | 1987-04-21 | 1990-07-24 | Mccormick Laboratories, Inc. | Device for accurately detecting the position of a ferromagnetic material inside biological tissue |
WO1993000039A1 (en) * | 1991-06-25 | 1993-01-07 | Ulrich Steinbeck | Detecting device for metallic foreign bodies in a living body |
WO1994024933A1 (en) * | 1993-04-26 | 1994-11-10 | St. Louis University | Indicating the position of a surgical probe |
-
1994
- 1994-09-22 SE SE9403193A patent/SE9403193L/en not_active Application Discontinuation
-
1995
- 1995-09-22 EP EP95933014A patent/EP0955879A1/en not_active Withdrawn
- 1995-09-22 WO PCT/SE1995/001082 patent/WO1996008999A1/en not_active Application Discontinuation
- 1995-09-22 JP JP8510822A patent/JPH10505776A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4445501A (en) * | 1981-05-07 | 1984-05-01 | Mccormick Laboratories, Inc. | Circuits for determining very accurately the position of a device inside biological tissue |
FI79458B (en) * | 1986-04-16 | 1989-09-29 | Seppo Peltola | OVER ANCHORING FOER STYRNING AV EN BEHANDLINGSANORDNING. |
US4943770A (en) * | 1987-04-21 | 1990-07-24 | Mccormick Laboratories, Inc. | Device for accurately detecting the position of a ferromagnetic material inside biological tissue |
WO1993000039A1 (en) * | 1991-06-25 | 1993-01-07 | Ulrich Steinbeck | Detecting device for metallic foreign bodies in a living body |
WO1994024933A1 (en) * | 1993-04-26 | 1994-11-10 | St. Louis University | Indicating the position of a surgical probe |
Cited By (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1181891A2 (en) * | 1997-05-08 | 2002-02-27 | Lucent Medical Systems, Inc. | A system for detecting a position of a magnet associated with an indwelling medical device |
US5879297A (en) * | 1997-05-08 | 1999-03-09 | Lucent Medical Systems, Inc. | System and method to determine the location and orientation of an indwelling medical device |
WO1998049938A1 (en) * | 1997-05-08 | 1998-11-12 | Lucent Medical Systems, Inc. | System and method to determine the location and orientation of an indwelling medical device |
US6129668A (en) * | 1997-05-08 | 2000-10-10 | Lucent Medical Systems, Inc. | System and method to determine the location and orientation of an indwelling medical device |
EP1181891A3 (en) * | 1997-05-08 | 2002-03-06 | Lucent Medical Systems, Inc. | A system for detecting a position of a magnet associated with an indwelling medical device |
US6216028B1 (en) | 1997-05-08 | 2001-04-10 | Lucent Medical Systems, Inc. | Method to determine the location and orientation of an indwelling medical device |
US6263230B1 (en) | 1997-05-08 | 2001-07-17 | Lucent Medical Systems, Inc. | System and method to determine the location and orientation of an indwelling medical device |
WO1998052466A1 (en) * | 1997-05-21 | 1998-11-26 | Lucent Medical Systems, Inc. | Non-invasive sensing of a physical parameter |
US6675810B2 (en) | 1998-05-14 | 2004-01-13 | Calypso Medical Technologies, Inc. | System and method for bracketing and removing tissue |
US6698433B2 (en) | 1998-05-14 | 2004-03-02 | Calypso Medical Technologies, Inc. | System and method for bracketing and removing tissue |
WO2000051514A1 (en) * | 1999-03-01 | 2000-09-08 | Lucent Medical Systems, Inc. | Magnetic anatomical marker and method of use |
US6173715B1 (en) | 1999-03-01 | 2001-01-16 | Lucent Medical Systems, Inc. | Magnetic anatomical marker and method of use |
EP2314348A3 (en) * | 2001-06-08 | 2011-08-03 | Calypso Medical Technologies, INC. | Guided radiation therapy system |
WO2002100485A1 (en) * | 2001-06-08 | 2002-12-19 | Calypso Medical Technologies, Inc. | Guided radiation therapy system |
US7657302B2 (en) | 2001-06-08 | 2010-02-02 | Calypso Medical Technologies, Inc. | Guided radiation therapy system |
US7657303B2 (en) | 2001-06-08 | 2010-02-02 | Calypso Medical Technologies, Inc. | Guided radiation therapy system |
EP2289597A1 (en) * | 2001-06-08 | 2011-03-02 | Calypso Medical Technologies, INC. | Guided radiation therapy system |
US7657301B2 (en) | 2001-06-08 | 2010-02-02 | Calypso Medical Technologies, Inc. | Guided radiation therapy system |
US9072895B2 (en) | 2001-06-08 | 2015-07-07 | Varian Medical Systems, Inc. | Guided radiation therapy system |
WO2003011394A1 (en) * | 2001-07-27 | 2003-02-13 | Bhc Engineering, Lp | Method and device for monitoring real-time position of an area targeted by a radiosurgery system |
US7176798B2 (en) | 2001-12-20 | 2007-02-13 | Calypso Medical Technologies, Inc. | System for spatially adjustable excitation of leadless miniature marker |
US6838990B2 (en) | 2001-12-20 | 2005-01-04 | Calypso Medical Technologies, Inc. | System for excitation leadless miniature marker |
US6822570B2 (en) | 2001-12-20 | 2004-11-23 | Calypso Medical Technologies, Inc. | System for spatially adjustable excitation of leadless miniature marker |
US7696876B2 (en) | 2001-12-20 | 2010-04-13 | Calypso Medical Technologies, Inc. | System for spatially adjustable excitation of leadless miniature marker |
US6812842B2 (en) | 2001-12-20 | 2004-11-02 | Calypso Medical Technologies, Inc. | System for excitation of a leadless miniature marker |
US9616248B2 (en) | 2002-06-05 | 2017-04-11 | Varian Medical Systems, Inc. | Integrated radiation therapy systems and methods for treating a target in a patient |
US9682253B2 (en) | 2002-06-05 | 2017-06-20 | Varian Medical Systems, Inc. | Integrated radiation therapy systems and methods for treating a target in a patient |
AU2003265186B2 (en) * | 2002-10-01 | 2008-06-26 | Implantica Patent Ltd. | Detection of implanted injection port |
CN100342824C (en) * | 2002-10-01 | 2007-10-17 | 波滕西亚医疗公司 | Detection of implanted injection port |
WO2004030536A1 (en) * | 2002-10-01 | 2004-04-15 | Potencia Medical Ag | Detection of implanted injection port |
US8297030B2 (en) | 2002-12-30 | 2012-10-30 | Varian Medical Systems, Inc. | Methods for manufacturing packaged systems for implanting markers in a patient |
US6889833B2 (en) | 2002-12-30 | 2005-05-10 | Calypso Medical Technologies, Inc. | Packaged systems for implanting markers in a patient and methods for manufacturing and using such systems |
US8011508B2 (en) | 2002-12-30 | 2011-09-06 | Calypso Medical Technologies, Inc. | Packaged systems for implanting markers in a patient and methods for manufacturing and using such systems |
US7407054B2 (en) | 2002-12-30 | 2008-08-05 | Calypso Medical Technologies, Inc. | Packaged systems for implanting markers in a patient and methods for manufacturing and using such systems |
US8857043B2 (en) | 2002-12-30 | 2014-10-14 | Varian Medical Systems, Inc. | Method of manufacturing an implantable marker with a leadless signal transmitter |
WO2006077200A1 (en) * | 2005-01-18 | 2006-07-27 | Charité - Universitätsmedizin Berlin | Endoscopic marking agent, instruments for applying and detecting the marking agent and for operatively fixing the marked tissue area |
AU2006252293B2 (en) * | 2005-12-30 | 2011-10-13 | Depuy Products, Inc. | System and method for registering a bone of a patient with a computer assisted orthopaedic surgery system |
US8148978B2 (en) | 2005-12-30 | 2012-04-03 | Depuy Products, Inc. | Magnetic sensor array |
EP1803413A3 (en) * | 2005-12-30 | 2008-08-13 | DePuy Products, Inc. | Magnetic sensor array for bone registration in computer-assisted orthopaedic surgery |
US8862200B2 (en) | 2005-12-30 | 2014-10-14 | DePuy Synthes Products, LLC | Method for determining a position of a magnetic source |
AU2006252294B2 (en) * | 2005-12-30 | 2010-08-12 | Depuy Products, Inc. | Magnetic sensor array |
US8068648B2 (en) | 2006-12-21 | 2011-11-29 | Depuy Products, Inc. | Method and system for registering a bone of a patient with a computer assisted orthopaedic surgery system |
US9237860B2 (en) | 2008-06-05 | 2016-01-19 | Varian Medical Systems, Inc. | Motion compensation for medical imaging and associated systems and methods |
US9764160B2 (en) | 2011-12-27 | 2017-09-19 | HJ Laboratories, LLC | Reducing absorption of radiation by healthy cells from an external radiation source |
WO2023020241A1 (en) * | 2021-08-16 | 2023-02-23 | The University Of Hong Kong | Non-contact, non-radiation device that accurately locates multiple implants in patient's body |
Also Published As
Publication number | Publication date |
---|---|
JPH10505776A (en) | 1998-06-09 |
SE9403193L (en) | 1996-03-23 |
SE9403193D0 (en) | 1994-09-22 |
EP0955879A1 (en) | 1999-11-17 |
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