WO1995026783A1 - Potency package - Google Patents
Potency package Download PDFInfo
- Publication number
- WO1995026783A1 WO1995026783A1 PCT/US1995/003996 US9503996W WO9526783A1 WO 1995026783 A1 WO1995026783 A1 WO 1995026783A1 US 9503996 W US9503996 W US 9503996W WO 9526783 A1 WO9526783 A1 WO 9526783A1
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- WO
- WIPO (PCT)
- Prior art keywords
- electronic
- male
- stimulation
- transmitting
- exciting
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/26—Penis implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
Definitions
- This invention relates to medical devices and methods and in particular to devices and methods for the impotence correction.
- the principal methods presently used for impotence correction and treatment include: the use of psychiatric and pharmacological treatments, injections of vasoactive drugs into the penis, plastic surgery of penis muscle tissue and prosthetics implantation. These prior art techniques only deal with the erection problem and do not provide the capability emission and ejaculation.
- Patents 5,246,015; 5065744 and 4,869,241 provide mechanical support for producing an erection.
- Patents 5,236,904; 5,256,652 and 5,236,904 are the pharmaceutical type of impotence correction providing drugs administered to the penis.
- An electronic device is implanted inside the body. It is programmable and controllable from outside the body. The press of a button sends an electronic signal which initiates a process which simulates the body's natural reproductive processes.
- a programmable electronic device is implanted under abdominal muscle rectus.
- An electrical conductor is stitched to the surface of the pelvic splanchnic nerve. Stimulation of this nerve by a series of low voltage electrical pulses from the electronic device causes dilation of the penis arteries which results in an erection.
- the electronic device is controlled by a controller operated by the patient or his partner.
- a second preferred embodiment also provides for emission stimulation.
- Emission is stimulated by electrical excitation of the pelvic plexus nerves from separate conductors from the electronic device.
- the device may be preprogrammed to set in motion the emission and ejaculation processes at appropriate time intervals after start of the erection process, or the device can be programmed to permit the patient (or his partner) to initiate the emission and ejaculation processes.
- a drug such as papaverine is administration from a storage chamber in the device. The drug is transmitted via a tube to the penis. As with the first two embodiments control is in the hands of the patient. Additional embodiments of the present invention are represented by various combinations of the above described embodiments. Brief Description of the Drawings
- FIG. 1 is a drawing describing how God designed the human male reproductive system.
- FIG. 2 is a drawing of the cross section of a human penis.
- FIG. 3 is a drawing of a signal generator portion of a first preferred embodiment of the present invention.
- FIG. 4 is the control unit of the device in FIG. 3.
- FIG. 5 shows a preferred placement of the above first preferred embodiment in a human male.
- FIG. 6 shows the function of the males reproductive system with the above preferred embodiment.
- FIGS. 7 A and B show a preferred method of connecting electrodes to nerve fibers.
- FIG. 8 shows a signal generator portion of a second preferred embodiment.
- FIG. 9 shows the function of the males reproductive system with the second preferred embodiment.
- FIG. 10 shows a third signal generator, also incorporating a drug dispenser feature.
- FIG. 11 shows where to connect the electrodes from signal generator shown in FIG. 7.
- FIG. 12 shows a preferred pulse program for the FIG. 3 device.
- FIG. 13 shows a preferred pulse program for the FIG. 8 device.
- Erection of the penis 2 is generally a necessary prerequisite for penetratio of the vagina.
- the stimuli for this reflex may involve either periphera nerve receptors on or around the penis or mental stimulation.
- the stimul are in the form of electrical signals. These signals are transmitted via routes 4 and 6, respectively, to central connections located in the sacral part of th spinal cord as shown at 8. From these central connections electrical signals are transmitted via the pelvic splanchnic nerves (the nervi ergentes) 9 t the penis.
- the pelvic splanchnic nerves provide electrical signals to the penis arteries (including the dorsal artery 10 shown in FIGS. 1 and 2 and very large number of smaller arteries inside the penis).
- FIG. 2 shows a cross section view of the penis including the corpora cavernosa 12 and corpus spongiosum 13. Also shown are the two limbs of the dorsal artery 10 and the dorsal nerve 9, side by side at the top of the penis, the dorsal veins 11 and the urethra 14.
- Emission is the movement of spermatozoa and secretions from the testes and other accessory glands into the urethra. This is entirely a reflex process.
- the afferent side of the reflex arc is initiated by touch receptors in the genital area such as receptors in the penis glans 15.
- In coming electrical signals travel via the pudendal nerves 17 to central relays in the upper lumbar segments 18 of the spinal cord. From there electrical signals travel via the pelvic plexus nerves 19 to stimulate parasympathetic fibres which in turn stimulate the ductus deferens 20 to slowly pump sperm and the seminal vesicles 22 to slowly pump siminal fluid into the urethra.
- Ejaculation is the propulsion of semen out of the urethra. The same afferent paths are involved. Central connections are located in the lower lumbar and upper sacral segments of the spinal cords. Efferent stimuli are conveyed by parasympathetic fibres of the pelvic splanchnic nerves 9 and by somatic motor fibres 23 in the pudendal nerves 17. Ejaculation is caused by the rhythmic contraction of the bulbocavernosus muscles 24, while the internal vesicle sphincter 26 closes to prevent retrograde ejaculation into the bladder 28.
- FIG. 3 is a block diagram of a device which the Inventors call a potency package.
- a preferred prototype embodiment comprises a modified commercial pacemaker Model 600AV manufactured by Seimens.
- the device is designed to be installed under the patient's abdominal muscle rectus, but it could be installed in several other convenient places.
- the unit comprises battery 40, programable signal circuit 42, infarred detector 44 and pulse generator 46.
- the unit is controlled with an external control unit shown in block diagram for in FIG. 4.
- the unit comprises a start button and an interrupt button.
- a preferred sequence of pulses which should provide good results for many patients is shown in FIG. 12.
- the package can be reprogrammed to change any of the parameters shown in FIG. 12 which are pulse height, pulse width, frequency, duration and sequence.
- the best program for each individual patient can only be determined by testing. These parameters such as number of pulses group, voltage, pace, pulse duration are well within the ranges available with the above Seimens device. These parameters and any others within the range of the device can be programmed into it with commercially available pacemaker programmer such as Model # 3CMHK 850 supplied by MIFI.
- the programmer transmits programming information via a pulsating magnetic field generated in the programmer to an electromagnetic detector in programmable signal circuit 42.
- This device shown in FIG. 3 comprises one electrode 48.
- the electrode should preferably be run from under the just patient's abdominal muscle rectus at position 30, under the abdominal skin tissue to location 34 as shown in FIG. 5 and there connect with the pelvic splanchnic nerves 9.
- the pelvic splanchnic nerve is located about one centimeter under the skin at the location shown on FIG. 5.
- the procedure can be accomplished in a medical doctors office or hospital, under local anesthesia.
- the nerve is located by a 5 cm incision at location 34.
- the nerve may be clamped between electrode leads as shown in FIGS. 6A and 6B. (Persons skilled in the art will recognize that many other surgical techniques for connecting electrodes to nerve tissue could be used.)
- the recommended electronic pulse series is shown in FIG. 5. If this series does not produce the desired effect, the doctor can vary the parameters. If an erection is produced by any of the tests, then the doctor continues the process and installs the potency package as described above. If the doctor is unable to produce an erection, he may choose not to proceed with the operation.
- FIG. 7 A second preferred embodiment of our potency package is shown in FIG. 7. This embodiment is just like the first embodiment except the potency package comprises a second pulse generator 47 which is programmed to simulate emission.
- a second electrode 49 from the device is connected to the pudendal nerves 17 at location 36 as shown in FIG. 9. Location 36 is also shown on FIG. 11. This nerve can most easily be reached by making a 1 cm incision of the skin in the pubic area just at the location shown at 36 in FIG. 11. Them
- SUBSTITUTE SHEET (RULE 2 ⁇ ) make an incision of the rectal muscle ligament and reach the nerve- vessel-ductus deferens bimdle. Make a 0.5 cm incision in the cover of the bundle and attach the electrode to the pelvic plexus nerve. The place of attachment is also shown in FIG. 9 at 36.
- Applicants recommend that a patient be tested prior to installation of the device to determine if the emission can be stimulated the particular patient. Applicants recommend that initially the potency package be programmed to produce the pulse trains shown in FIG. 13
- the device shown in FIG. 10 contains a chamber 60 for storage within the body of a suitable drug such as papaverine, a small electronic pump 62 and a very thin tube 64 for delivering the drug to the penis.
- a suitable drug such as papaverine
- the tube is run under the skin of the abdomen to the upper part of the penis.
- the tube then branches into 3 branches, one each to the two corpora cavernosa and one for the corpus spongiosium.
- the delivery of the drug is initiated by an electronic signal transmitted by a hand held transmitter within the control of the patient.
- the two electronic circuits are programmed as described for the second preferred embodiment as described above.
- the potency package is programmed to deliver the drug at time zero.
- Drug delivery chambers consists of a plastic refillable containers which is placed into hermetic chamber 62.
- the bottom of the chamber is a piston with a coil and electromagnet step driver.
- As the first step of the erection stimulation is a vasoactive drug delivered by sending an electrical potential to the driver.
- the driver pulls the coil into the electromagnet up to a definite distance squeezing the drug into the tube attached to the plastic container with one end and implanted into cavernous bodies of the penis at the other end of the tube.
- the other drug chambers for various health condition correction are built similarly. They are refillable as well by injection through the skin with a syringe injector.
- the potency package components can be standard off-the-shelf components.
- the components include: a lithium battery LBSAR 5 made by SARATOF with a lifetime of 5 to 8 years, a pulse generator QG 445 made by MIFI, a receiver/ transmitter MC 145027 made by Motorola and IR remote control receiver U338M made by AEG Corporation, a fast IR photodiode detector si 133-11 made by Hamamatsu, IR remote control transmitter U327M made by AEG Corporation, stepping motor 155 NL Micro Slide made by Toshiba Corporation, silicon tubing catheter T5715 made by Dow Corning Silasastic and elastomer O7-4750 silicon pack made by Dow Corning Silas tic.
- the Surgery includes: a lithium battery LBSAR 5 made by SARATOF with a lifetime of 5 to 8 years, a pulse generator QG 445 made by MIFI, a receiver/ transmitter MC 145027 made by Motorola and IR remote control receiver U338M made by AEG Corporation, a fast
- the surgery to provide implantation is described with respect of the sixth embodiment which includes electrodes for erection and for emission and a thin tube for drug delivery to the penis.
- the potency package should be surgically implanted by a trained physician. The operation is very similar to the implantation of a heart pacemaker. A skin dissection is performed on the alba line below the umbilical. The peritoneal cavity is dissected and the path to the retroperitoneal is opened on the level of L4-S2. The electrodes are passed from the retroperitoneal to the subcutaneous layer of the frontal abdominal wall, where they are connected with the stimulator. Using micro surgical techniques, the carbonic electrode 28 is sewn to the parasimpatic nerve fiber and carbonic electrode 30 is sewn to the fauxc nerve fiber.
- the electrodes are passed from the retroperitoneal to the subcutaneous layer of the frontal abdominal wall where they are connected with the chambers 10 and 12 of the potency package.
- the tube carrying the drug is connected to the corpora cavernosa so as to deliver this drug to directly to the penis.
- the potency package is implanted subcutaneously to the frontal abdominal wall either to the right or to the left above the umbilical. The package has no contact with the operational wound. The wound is sewn layerly.
- Additional embodiments are provided by providing more than one dru
- a drug such as nitroglycerine could be provided to released into the blood stream to provide protection of patients again heart attack during sex.
- the following table shows some dru recommended for the correction of health conditions which are the mo common appeared during sex intercourse.
- Electrodes may also be provided to stimulate the penal muscles. Medical doctors will recognize that electrodes can be connected at many locations other than the ones shown.
- anastamosis should be performed at the same time as potency implantation. Anastomosis between inferior hypogastric artery and central and dorsal artery and dorsal vein of penis is preferable.
- the arterial anastamosis should be done as distal to the penile glans as possible and same time as potency pack implantation. Anastomosis between the hypogastric artery and dorsal artery end-to-end or end-to-side. Penile veins of diabetic patients could usually provide blood flow and their surgical correction is not required in most cases.
- the teachings of the present invention can be applied to many animals other than man. It should be especially valuable for use with breeding animals such as prize bulls. It could also be used in the breeding programs of captured members of endangered species of wild animals. While the above description contains many specificities, the reader should not construe these as limitations on the scope of the invention, buy merely as exemplifications of preferred embodiments thereof. Those skilled in the art will envision many other possible variations are within its scope like pacemaker implantation in other location than under the rectal muscle of abdomen, design different types of electrodes and pacemakers, to use different voltage, amplitude, pulse group, repetition rate, pulse duration, remote control with more or less functions, fully automatic preprogrammed pacemaker without external control, etc.
Abstract
This invention is a device and method for impotence correction. The device is implanted inside the body and is programmable and controllable from outside the body with the aid of an IR detector (44) and a programmable signal circuit (42). The press of a button sends a signal which initiates a process that simulates the body's natural reproductive processes. In a preferred embodiment, a programmable electronic device is implanted under abdominal muscle rectus. An electrical conductor (48) is fixed to the surface of the pelvic splanchnic nerve. Stimulation of this nerve by low voltage electrical pulses provided by a pulse generator (46) causes the release of neuro-mediator which causes penis arterioles dilation which initiates erection. The electronic device is controlled by a controller operated by the patient or his partner. A second preferred embodiment also provides for emission stimulation. Emission is stimulated by electrical excitation of the pelvic plexus nerves from separate conductors from the electronic device.
Description
POTENCY PACKAGE
This invention relates to medical devices and methods and in particular to devices and methods for the impotence correction.
Background of the Invention
In the human male as with many higher order animals, sexual performance involves three functions: erection, emission and ejaculation. A wide variety of medical or psychological problems can interfere with one or more of these functions. The inability to achieve and erection is referred to a impotency.
The principal methods presently used for impotence correction and treatment include: the use of psychiatric and pharmacological treatments, injections of vasoactive drugs into the penis, plastic surgery of penis muscle tissue and prosthetics implantation. These prior art techniques only deal with the erection problem and do not provide the capability emission and ejaculation.
Patents 5,246,015; 5065744 and 4,869,241 provide mechanical support for producing an erection. Patents 5,236,904; 5,256,652 and 5,236,904 are the pharmaceutical type of impotence correction providing drugs administered to the penis.
What is needed is an effective device and method for correcting dysfunctional impotence which simulates the natural processes of erection and ejaculation as closely as feasible.
Summary of the Invention
Present invention provides a device and method for impotence correction. An electronic device is implanted inside the body. It is programmable and controllable from outside the body. The press of a button sends an electronic signal which initiates a process which simulates the body's natural reproductive processes. In a preferred embodiment, a programmable electronic device is implanted under abdominal muscle rectus. An electrical conductor is stitched to the surface of the pelvic splanchnic nerve. Stimulation of this nerve by a series of low voltage electrical pulses from the electronic device causes dilation of the penis arteries which results in an erection. The electronic device is controlled by a controller operated by the patient or his partner. A second preferred embodiment also provides for emission stimulation. Emission is stimulated by electrical excitation of the pelvic plexus nerves from separate conductors from the electronic device. The device may be preprogrammed to set in motion the emission and ejaculation processes at appropriate time intervals after start of the erection process, or the device can be programmed to permit the patient (or his partner) to initiate the emission and ejaculation processes. In a third preferred embodiment a drug such as papaverine is administration from a storage chamber in the device. The drug is transmitted via a tube to the penis. As with the first two embodiments control is in the hands of the patient. Additional embodiments of the present invention are represented by various combinations of the above described embodiments.
Brief Description of the Drawings
FIG. 1 is a drawing describing how God designed the human male reproductive system.
FIG. 2 is a drawing of the cross section of a human penis.
FIG. 3 is a drawing of a signal generator portion of a first preferred embodiment of the present invention.
FIG. 4 is the control unit of the device in FIG. 3.
FIG. 5 shows a preferred placement of the above first preferred embodiment in a human male.
FIG. 6 shows the function of the males reproductive system with the above preferred embodiment.
FIGS. 7 A and B show a preferred method of connecting electrodes to nerve fibers.
FIG. 8 shows a signal generator portion of a second preferred embodiment.
FIG. 9 shows the function of the males reproductive system with the second preferred embodiment.
FIG. 10 shows a third signal generator, also incorporating a drug dispenser feature.
FIG. 11 shows where to connect the electrodes from signal generator shown in FIG. 7.
FIG. 12 shows a preferred pulse program for the FIG. 3 device.
FIG. 13 shows a preferred pulse program for the FIG. 8 device.
Detailed Description of Preferred Embodiments
Preferred embodiments of the present invention can be described by reference to the figures.
Natural Insemination
The natural interrelated mechanisms involved in the deposition of semen i the vagina by the natural means of copulation can be described by referenc to the diagram in FIG. 1.
Erection
Erection of the penis 2 is generally a necessary prerequisite for penetratio of the vagina. The stimuli for this reflex may involve either periphera nerve receptors on or around the penis or mental stimulation. The stimul are in the form of electrical signals. These signals are transmitted via routes 4 and 6, respectively, to central connections located in the sacral part of th spinal cord as shown at 8. From these central connections electrical signals are transmitted via the pelvic splanchnic nerves (the nervi ergentes) 9 t the penis. The pelvic splanchnic nerves provide electrical signals to the penis arteries (including the dorsal artery 10 shown in FIGS. 1 and 2 and very large number of smaller arteries inside the penis). These electrical signals result in a dilation of the arteries permitting an increase of blood flow into the penis which in turn increases the blood pressure which has the effect of partially restricting the veins 11 (including the dorsal veins show in FIGS. 1 and 2) taking blood out of the penis. As a result there is a rapid filling of blood spaces in the corpora cavernosa 12 and corpus spongiosum 13 areas of the penis. The net effect is erection. FIG. 2 shows a cross section view of the penis including the corpora cavernosa 12 and corpus spongiosum 13. Also shown are the two limbs of the dorsal artery 10 and
the dorsal nerve 9, side by side at the top of the penis, the dorsal veins 11 and the urethra 14.
Emission
Emission is the movement of spermatozoa and secretions from the testes and other accessory glands into the urethra. This is entirely a reflex process. The afferent side of the reflex arc is initiated by touch receptors in the genital area such as receptors in the penis glans 15. In coming electrical signals travel via the pudendal nerves 17 to central relays in the upper lumbar segments 18 of the spinal cord. From there electrical signals travel via the pelvic plexus nerves 19 to stimulate parasympathetic fibres which in turn stimulate the ductus deferens 20 to slowly pump sperm and the seminal vesicles 22 to slowly pump siminal fluid into the urethra.
Ejaculation
Ejaculation is the propulsion of semen out of the urethra. The same afferent paths are involved. Central connections are located in the lower lumbar and upper sacral segments of the spinal cords. Efferent stimuli are conveyed by parasympathetic fibres of the pelvic splanchnic nerves 9 and by somatic motor fibres 23 in the pudendal nerves 17. Ejaculation is caused by the rhythmic contraction of the bulbocavernosus muscles 24, while the internal vesicle sphincter 26 closes to prevent retrograde ejaculation into the bladder 28.
First Preferred Embodiment
FIG. 3 is a block diagram of a device which the Inventors call a potency package. A preferred prototype embodiment comprises a modified commercial pacemaker Model 600AV manufactured by Seimens. The device is designed to be installed under the patient's abdominal muscle rectus, but it could be installed in several other convenient places. The unit comprises battery 40, programable signal circuit 42, infarred detector 44 and pulse generator 46. The unit is controlled with an external control unit shown in block diagram for in FIG. 4. The unit comprises a start button and an interrupt button. A preferred sequence of pulses which should provide good results for many patients is shown in FIG. 12. The package can be reprogrammed to change any of the parameters shown in FIG. 12 which are pulse height, pulse width, frequency, duration and sequence. The best program for each individual patient can only be determined by testing. These parameters such as number of pulses group, voltage, pace, pulse duration are well within the ranges available with the above Seimens device. These parameters and any others within the range of the device can be programmed into it with commercially available pacemaker programmer such as Model # 3CMHK 850 supplied by MIFI. The programmer transmits programming information via a pulsating magnetic field generated in the programmer to an electromagnetic detector in programmable signal circuit 42. This device shown in FIG. 3 comprises one electrode 48. The electrode should preferably be run from under the just patient's abdominal muscle rectus at
position 30, under the abdominal skin tissue to location 34 as shown in FIG. 5 and there connect with the pelvic splanchnic nerves 9. The pelvic splanchnic nerve is located about one centimeter under the skin at the location shown on FIG. 5. The procedure can be accomplished in a medical doctors office or hospital, under local anesthesia. The nerve is located by a 5 cm incision at location 34. The nerve may be clamped between electrode leads as shown in FIGS. 6A and 6B. (Persons skilled in the art will recognize that many other surgical techniques for connecting electrodes to nerve tissue could be used.)
The recommended electronic pulse series is shown in FIG. 5. If this series does not produce the desired effect, the doctor can vary the parameters. If an erection is produced by any of the tests, then the doctor continues the process and installs the potency package as described above. If the doctor is unable to produce an erection, he may choose not to proceed with the operation.
Second Preferred Embodiment
A second preferred embodiment of our potency package is shown in FIG. 7. This embodiment is just like the first embodiment except the potency package comprises a second pulse generator 47 which is programmed to simulate emission. A second electrode 49 from the device is connected to the pudendal nerves 17 at location 36 as shown in FIG. 9. Location 36 is also shown on FIG. 11. This nerve can most easily be reached by making a 1 cm incision of the skin in the pubic area just at the location shown at 36 in FIG. 11. Them
SUBSTITUTE SHEET (RULE 2β)
make an incision of the rectal muscle ligament and reach the nerve- vessel-ductus deferens bimdle. Make a 0.5 cm incision in the cover of the bundle and attach the electrode to the pelvic plexus nerve. The place of attachment is also shown in FIG. 9 at 36.
As above, if the doctor is uncertain if the patient is a good candidate for the procedure, Applicants recommend that a patient be tested prior to installation of the device to determine if the emission can be stimulated the particular patient. Applicants recommend that initially the potency package be programmed to produce the pulse trains shown in FIG. 13
Third Preferred Embodiment
In this embodiment the device, shown in FIG. 10 contains a chamber 60 for storage within the body of a suitable drug such as papaverine, a small electronic pump 62 and a very thin tube 64 for delivering the drug to the penis. The tube is run under the skin of the abdomen to the upper part of the penis. The tube then branches into 3 branches, one each to the two corpora cavernosa and one for the corpus spongiosium. As with the two previously described embodiments, the delivery of the drug is initiated by an electronic signal transmitted by a hand held transmitter within the control of the patient. For this embodiment the two electronic circuits are programmed as described for the second preferred embodiment as described above. The potency package is programmed to deliver the drug at time zero.
Drug delivery chambers consists of a plastic refillable containers which is placed into hermetic chamber 62. The bottom of the chamber is a piston with a coil and electromagnet step driver. As the first step of the erection stimulation is a vasoactive drug delivered by sending an electrical potential to the driver. The driver pulls the coil into the electromagnet up to a definite distance squeezing the drug into the tube attached to the plastic container with one end and implanted into cavernous bodies of the penis at the other end of the tube. The other drug chambers for various health condition correction are built similarly. They are refillable as well by injection through the skin with a syringe injector.
Equipment
The potency package components can be standard off-the-shelf components. The components include: a lithium battery LBSAR 5 made by SARATOF with a lifetime of 5 to 8 years, a pulse generator QG 445 made by MIFI, a receiver/ transmitter MC 145027 made by Motorola and IR remote control receiver U338M made by AEG Corporation, a fast IR photodiode detector si 133-11 made by Hamamatsu, IR remote control transmitter U327M made by AEG Corporation, stepping motor 155 NL Micro Slide made by Toshiba Corporation, silicon tubing catheter T5715 made by Dow Corning Silasastic and elastomer O7-4750 silicon pack made by Dow Corning Silas tic.
The Surgery
The surgery to provide implantation is described with respect of the sixth embodiment which includes electrodes for erection and for emission and a thin tube for drug delivery to the penis. The potency package should be surgically implanted by a trained physician. The operation is very similar to the implantation of a heart pacemaker. A skin dissection is performed on the alba line below the umbilical. The peritoneal cavity is dissected and the path to the retroperitoneal is opened on the level of L4-S2. The electrodes are passed from the retroperitoneal to the subcutaneous layer of the frontal abdominal wall, where they are connected with the stimulator. Using micro surgical techniques, the carbonic electrode 28 is sewn to the parasimpatic nerve fiber and carbonic electrode 30 is sewn to the simpatic nerve fiber. The electrodes are passed from the retroperitoneal to the subcutaneous layer of the frontal abdominal wall where they are connected with the chambers 10 and 12 of the potency package. The tube carrying the drug is connected to the corpora cavernosa so as to deliver this drug to directly to the penis. The potency package is implanted subcutaneously to the frontal abdominal wall either to the right or to the left above the umbilical. The package has no contact with the operational wound. The wound is sewn layerly.
Other Embodiments
Many other embodiments of the present invention are provided by various combinations of the above described embodiments. A forth
embodiment would provide for emission stimulation only, a fifth is drug only.
The following table lists vasoactive drugs and recommended quantities:
Vasoactive Agent Average Dose per Injection Papaverine 15 mg
Phentolamine 0.5 mg
Prostaglandin El 20 μg
Vasoactive Intestinal Polypeptide 5 μg
Additional embodiments are provided by providing more than one dru For example a drug such as nitroglycerine could be provided to released into the blood stream to provide protection of patients again heart attack during sex. The following table shows some dru recommended for the correction of health conditions which are the mo common appeared during sex intercourse.
Health Condition Medication
Arrhythmia Beta-blockers
Asthma Alpha-blockers
Angina Nitroglycerin
Hypertension Vasodilators
Additional embodiments are provided by using many different drugs which are known to induce erection. Also, there are many electronic pulse sequences which would work well to produce erection,
emission and ejaculation for many different patients in addition to the sequences described above. Electrodes may also be provided to stimulate the penal muscles. Medical doctors will recognize that electrodes can be connected at many locations other than the ones shown.
To correct the arterial circulatory problem of impotence the art anastamosis should be performed at the same time as potency implantation. Anastomosis between inferior hypogastric artery and central and dorsal artery and dorsal vein of penis is preferable.
Diabetic Type of Impotence Correction
To correct the diabetic circulatory problem of impotence the arterial anastamosis should be done as distal to the penile glans as possible and same time as potency pack implantation. Anastomosis between the hypogastric artery and dorsal artery end-to-end or end-to-side. Penile veins of diabetic patients could usually provide blood flow and their surgical correction is not required in most cases.
Animal Use
The teachings of the present invention can be applied to many animals other than man. It should be especially valuable for use with breeding animals such as prize bulls. It could also be used in the breeding programs of captured members of endangered species of wild animals.
While the above description contains many specificities, the reader should not construe these as limitations on the scope of the invention, buy merely as exemplifications of preferred embodiments thereof. Those skilled in the art will envision many other possible variations are within its scope like pacemaker implantation in other location than under the rectal muscle of abdomen, design different types of electrodes and pacemakers, to use different voltage, amplitude, pulse group, repetition rate, pulse duration, remote control with more or less functions, fully automatic preprogrammed pacemaker without external control, etc. Persons skilled in art will recognize that the teachings of this invention can be applied to treat frigidity in women by clitoris erection stimulation. In this case an electronic device is provided with two electrodes: one provides for erection of the clitoris and the other for pudendal muscle contraction around the vaginal entrance. Other elements in the women's device might provide for and electrode for urethra muscles contraction for urine incontinence correction during sexual intercourse. Accordingly the reader is requested to determine the scope of the invention by the appended claims and their legal equivalents, and not by the examples which have been given.
Claims
1. A device for the cure of impotency comprising: a) an electronic exciting means for providing stimulation to a sex organ of a male human, said means being surgically installed under the skin of said male human, b) a transmitting means for transmitting said stimulation from said exciting means to said sex organ, c) a means for programming said exciting means, d) an electronic control means for controlling said exciting means so as to initiate and control said stimulation.
2. A device as in Claim 1 wherein said electronic exciting means comprises at least one electronic pulse generator.
3. A device as in Claim 2 wherein said transmitting means comprises an electrode connecting said electronic exciting means to pelvic splanchnic nerve of said male human.
4. A device as in Claim 2 wherein said transmitting means comprises an electrode connecting said electronic exciting means to pelvic plexus nerve of said male human.
5. A device as in Claim 3 wherein said electronic exciting means is programmable to produce electrical pulses.
6. A device as in Claim 4 wherein said electronic exciting means is programmable to produce electrical pulses.
7. A device as in Claim 2 wherein said at least one pulse generator is two pulse generators and said transmitter means comprises a first electrode connecting said electronic exciting means to pelvic plexus nerve of said male humans and a second electrode connecting said electronic exciting means to pelvic plexus nerve of said male human.
8. A device as in Claim 1 wherein said electronic exciting means comprises a storage vessel for the storage of a vasoactive drug and said transmitting means comprises a thin tube for transmitting said vasoactive drug to the penis of said human male.
9. A device as in Claim 2 wherein said at least one pulse generator is two pulse generators and said transmitter means comprises a first electrode connecting said electronic exciting means to pelvic plexus nerve of said male humans and a second electrode connecting said electronic exciting means to pelvic plexus nerve of said male human, and wherein said electronic exciting means also comprises a storage vessel for the storage of a vasoactive drug and said transmitting means comprises a thin tube for transmitting said vasoactive drug to the penis of said human male.
10. A method of correcting impotency in a human male comprising the steps of: a) surgically implanting under the skin of said human male a programmable electronic stimulation means, b) surgically implanting a transmitting means for transmitting a stimulation from said exciting means to a sex organ of said human male, c) providing a means for programming said programmable electronic stimulation means, d) providing said human male with an electronic control means for controlling said exciting means so as to initiate and control said stimulation so as to produce erection, emission and ejaculation.
11. A device for the cure of impotency comprising: a) an electronic exciting means for providing stimulation to a sex organ of a male animal, said means being surgically installed under the skin of said male animal, b) a transmitting means for transmitting said stimulation from said exciting means to said sex organ, c) a means for programming said exciting means, d) an electronic control means for controlling said exciting means so as to initiate and control said stimulation.
12. A device as in Claim 11 wherein said animal is a domesticated animal.
13. A device as in Claim 11 wherein said animal is a captured wild animal.
Priority Applications (3)
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AU22348/95A AU2234895A (en) | 1994-04-05 | 1995-04-03 | Potency package |
JP7525858A JPH09511421A (en) | 1994-04-05 | 1995-04-03 | Impotence correction device |
EP95915479A EP0757576A4 (en) | 1994-04-05 | 1995-04-03 | Potency package |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US08/223,160 US5454840A (en) | 1994-04-05 | 1994-04-05 | Potency package |
US08/223,160 | 1994-04-05 |
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WO1995026783A1 true WO1995026783A1 (en) | 1995-10-12 |
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PCT/US1995/003996 WO1995026783A1 (en) | 1994-04-05 | 1995-04-03 | Potency package |
Country Status (5)
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US (1) | US5454840A (en) |
EP (1) | EP0757576A4 (en) |
JP (1) | JPH09511421A (en) |
AU (1) | AU2234895A (en) |
WO (1) | WO1995026783A1 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7689276B2 (en) | 2002-09-13 | 2010-03-30 | Leptos Biomedical, Inc. | Dynamic nerve stimulation for treatment of disorders |
US7702386B2 (en) | 2002-03-22 | 2010-04-20 | Leptos Biomedical, Inc. | Nerve stimulation for treatment of obesity, metabolic syndrome, and Type 2 diabetes |
US7937144B2 (en) | 2002-03-22 | 2011-05-03 | Advanced Neuromodulation Systems, Inc. | Electric modulation of sympathetic nervous system |
US8838231B2 (en) | 2002-03-22 | 2014-09-16 | Advanced Neuromodulation Systems, Inc. | Neural Stimulation for treatment of metabolic syndrome and type 2 diabetes |
Families Citing this family (178)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5938584A (en) * | 1997-11-14 | 1999-08-17 | Cybernetic Medical Systems Corporation | Cavernous nerve stimulation device |
US6368268B1 (en) | 1998-08-17 | 2002-04-09 | Warren J. Sandvick | Method and device for interactive virtual control of sexual aids using digital computer networks |
US6169924B1 (en) | 1999-04-27 | 2001-01-02 | T. Stuart Meloy | Spinal cord stimulation |
US6471635B1 (en) | 2000-02-10 | 2002-10-29 | Obtech Medical Ag | Anal incontinence disease treatment with controlled wireless energy supply |
US6450173B1 (en) | 1999-08-12 | 2002-09-17 | Obtech Medical Ag | Heartburn and reflux disease treatment with controlled wireless energy supply |
US6464628B1 (en) | 1999-08-12 | 2002-10-15 | Obtech Medical Ag | Mechanical anal incontinence |
US6482145B1 (en) | 2000-02-14 | 2002-11-19 | Obtech Medical Ag | Hydraulic anal incontinence treatment |
AU759363B2 (en) | 2000-02-10 | 2003-04-10 | Implantica Patent Ltd. | Controlled urinary incontinence treatment |
EP1253877B1 (en) | 2000-02-10 | 2005-05-11 | Potencia Medical AG | Mechanical impotence treatment apparatus |
EP1253879B1 (en) * | 2000-02-10 | 2005-10-12 | Potencia Medical AG | Urinary incontinence treatment with wireless energy supply |
AU778406B2 (en) | 2000-02-11 | 2004-12-02 | Potentica Ag | Controlled impotence treatment |
US20030125768A1 (en) * | 2000-02-11 | 2003-07-03 | Forsell Peter | Impotence treatment apparatus with energy transforming means |
EP1255514B1 (en) | 2000-02-14 | 2006-04-26 | Potencia Medical AG | Male impotence prosthesis apparatus with wireless energy supply |
US20030100929A1 (en) * | 2000-02-14 | 2003-05-29 | Peter Forsell | Controlled penile prosthesis |
DE60111019T2 (en) | 2000-02-14 | 2006-05-11 | Potencia Medical Ag | PROSTHESIS |
US6402683B1 (en) * | 2000-02-17 | 2002-06-11 | Jean-Claude Marty | Vaginal stimulator and device for the treatment of female urinary incontinence |
US6650943B1 (en) | 2000-04-07 | 2003-11-18 | Advanced Bionics Corporation | Fully implantable neurostimulator for cavernous nerve stimulation as a therapy for erectile dysfunction and other sexual dysfunction |
US6862479B1 (en) | 2000-08-30 | 2005-03-01 | Advanced Bionics Corporation | Spinal cord stimulation as a therapy for sexual dysfunction |
CA2328568A1 (en) * | 2000-12-12 | 2002-06-12 | Universite De Sherbrooke | Implantable, programmable nerve prosthesis |
JP2004526510A (en) * | 2001-03-30 | 2004-09-02 | ケース ウエスタン リザーブ ユニバーシティ | Systems and methods for selectively stimulating components in, on, or near pudendal nerves or pudendal nerve branches to achieve selective physiological responses |
US7047078B2 (en) * | 2001-03-30 | 2006-05-16 | Case Western Reserve University | Methods for stimulating components in, on, or near the pudendal nerve or its branches to achieve selective physiologic responses |
US6892098B2 (en) * | 2001-04-26 | 2005-05-10 | Biocontrol Medical Ltd. | Nerve stimulation for treating spasticity, tremor, muscle weakness, and other motor disorders |
US6885895B1 (en) * | 2001-04-26 | 2005-04-26 | Advanced Bionics Corporation | Methods and systems for electrical and/or drug stimulation as a therapy for erectile dysfunction |
US6907295B2 (en) | 2001-08-31 | 2005-06-14 | Biocontrol Medical Ltd. | Electrode assembly for nerve control |
US20040125120A1 (en) * | 2001-06-08 | 2004-07-01 | Michael Weiner | Method and apparatus for interactive transmission and reception of tactile information |
US7734355B2 (en) | 2001-08-31 | 2010-06-08 | Bio Control Medical (B.C.M.) Ltd. | Treatment of disorders by unidirectional nerve stimulation |
US7885709B2 (en) | 2001-08-31 | 2011-02-08 | Bio Control Medical (B.C.M.) Ltd. | Nerve stimulation for treating disorders |
US7904176B2 (en) | 2006-09-07 | 2011-03-08 | Bio Control Medical (B.C.M.) Ltd. | Techniques for reducing pain associated with nerve stimulation |
US7778711B2 (en) | 2001-08-31 | 2010-08-17 | Bio Control Medical (B.C.M.) Ltd. | Reduction of heart rate variability by parasympathetic stimulation |
US8571653B2 (en) | 2001-08-31 | 2013-10-29 | Bio Control Medical (B.C.M.) Ltd. | Nerve stimulation techniques |
US7778703B2 (en) | 2001-08-31 | 2010-08-17 | Bio Control Medical (B.C.M.) Ltd. | Selective nerve fiber stimulation for treating heart conditions |
US7974693B2 (en) | 2001-08-31 | 2011-07-05 | Bio Control Medical (B.C.M.) Ltd. | Techniques for applying, configuring, and coordinating nerve fiber stimulation |
US20080033491A1 (en) * | 2001-12-03 | 2008-02-07 | Zappala Stephen M | Implantable Device and Method for Transvascular Neuromodulation |
US6993390B2 (en) * | 2001-12-03 | 2006-01-31 | Zappala Stephen M | Implantable device and method for managing erectile dysfunction |
US7937145B2 (en) * | 2002-03-22 | 2011-05-03 | Advanced Neuromodulation Systems, Inc. | Dynamic nerve stimulation employing frequency modulation |
US7551964B2 (en) * | 2002-03-22 | 2009-06-23 | Leptos Biomedical, Inc. | Splanchnic nerve stimulation for treatment of obesity |
US20090259279A1 (en) * | 2002-03-22 | 2009-10-15 | Dobak Iii John D | Splanchnic nerve stimulation for treatment of obesity |
US7236822B2 (en) * | 2002-03-22 | 2007-06-26 | Leptos Biomedical, Inc. | Wireless electric modulation of sympathetic nervous system |
US7885711B2 (en) | 2003-06-13 | 2011-02-08 | Bio Control Medical (B.C.M.) Ltd. | Vagal stimulation for anti-embolic therapy |
US8204591B2 (en) | 2002-05-23 | 2012-06-19 | Bio Control Medical (B.C.M.) Ltd. | Techniques for prevention of atrial fibrillation |
US7321793B2 (en) | 2003-06-13 | 2008-01-22 | Biocontrol Medical Ltd. | Vagal stimulation for atrial fibrillation therapy |
US7844346B2 (en) | 2002-05-23 | 2010-11-30 | Biocontrol Medical Ltd. | Electrode assembly for nerve control |
US7561922B2 (en) | 2004-12-22 | 2009-07-14 | Biocontrol Medical Ltd. | Construction of electrode assembly for nerve control |
US20040015205A1 (en) | 2002-06-20 | 2004-01-22 | Whitehurst Todd K. | Implantable microstimulators with programmable multielectrode configuration and uses thereof |
US7203548B2 (en) | 2002-06-20 | 2007-04-10 | Advanced Bionics Corporation | Cavernous nerve stimulation via unidirectional propagation of action potentials |
US7292890B2 (en) | 2002-06-20 | 2007-11-06 | Advanced Bionics Corporation | Vagus nerve stimulation via unidirectional propagation of action potentials |
US7860570B2 (en) | 2002-06-20 | 2010-12-28 | Boston Scientific Neuromodulation Corporation | Implantable microstimulators and methods for unidirectional propagation of action potentials |
EP1539262A1 (en) | 2002-07-29 | 2005-06-15 | Potencia Medical AG | Durable implant |
US20040034275A1 (en) | 2002-07-29 | 2004-02-19 | Peter Forsell | Multi-material incontinence treatment constriction device |
US20050033374A1 (en) * | 2002-09-06 | 2005-02-10 | Medtronic, Inc. | Method, system and device for treating disorders of the pelvic floor by electrical stimulation of and the delivery of drugs to various nerves or tissues |
US7276057B2 (en) * | 2002-09-06 | 2007-10-02 | Medtronic, Inc. | Method, system and device for treating disorders of the pelvic floor by drug delivery to the pudendal and sacral nerves |
US7427280B2 (en) * | 2002-09-06 | 2008-09-23 | Medtronic, Inc. | Method, system and device for treating disorders of the pelvic floor by delivering drugs to various nerves or tissues |
US7328069B2 (en) * | 2002-09-06 | 2008-02-05 | Medtronic, Inc. | Method, system and device for treating disorders of the pelvic floor by electrical stimulation of and the delivery of drugs to the left and right pudendal nerves |
US20050070969A1 (en) * | 2002-09-06 | 2005-03-31 | Medtronic, Inc. | Method, system and device for treating disorders of the pelvic floor by electrical stimulation and the delivery of drugs to the sacral and pudendal nerves |
US20050113878A1 (en) * | 2003-11-26 | 2005-05-26 | Medtronic, Inc. | Method, system and device for treating various disorders of the pelvic floor by electrical stimulation of the pudendal nerves and the sacral nerves at different sites |
US7369894B2 (en) * | 2002-09-06 | 2008-05-06 | Medtronic, Inc. | Method, system and device for treating disorders of the pelvic floor by electrical stimulation of the sacral and/or pudendal nerves |
US7328068B2 (en) * | 2003-03-31 | 2008-02-05 | Medtronic, Inc. | Method, system and device for treating disorders of the pelvic floor by means of electrical stimulation of the pudendal and associated nerves, and the optional delivery of drugs in association therewith |
US20050020970A1 (en) * | 2002-09-06 | 2005-01-27 | Medtronic, Inc. | Method, system and device for treating disorders of the pelvic floor by delivering drugs to the pudendal nerves |
US7627384B2 (en) * | 2004-11-15 | 2009-12-01 | Bio Control Medical (B.C.M.) Ltd. | Techniques for nerve stimulation |
US8880192B2 (en) | 2012-04-02 | 2014-11-04 | Bio Control Medical (B.C.M.) Ltd. | Electrode cuffs |
US20040181261A1 (en) * | 2002-12-16 | 2004-09-16 | Joseph Manne | Cavernous nerve stimulation device |
GB2397529A (en) * | 2003-01-29 | 2004-07-28 | Jonathan Richard Swift | Control Belt |
EP1587463B8 (en) * | 2003-01-31 | 2007-04-25 | Oblicus AG | Electrically operable incontinence treatment apparatus |
EP1587455B8 (en) * | 2003-01-31 | 2007-05-02 | Instant Communication AG | Electrically operable impotence treatment apparatus |
US20040225713A1 (en) * | 2003-05-07 | 2004-11-11 | Link2Link Corp. | System and method for multi-way remote and local device control, enabling recording and replay of control commands and data |
US20040226556A1 (en) | 2003-05-13 | 2004-11-18 | Deem Mark E. | Apparatus for treating asthma using neurotoxin |
US8060197B2 (en) | 2003-05-23 | 2011-11-15 | Bio Control Medical (B.C.M.) Ltd. | Parasympathetic stimulation for termination of non-sinus atrial tachycardia |
US7343202B2 (en) | 2004-02-12 | 2008-03-11 | Ndi Medical, Llc. | Method for affecting urinary function with electrode implantation in adipose tissue |
US7437194B2 (en) * | 2003-10-31 | 2008-10-14 | Medtronic, Inc. | Stimulating the prostate gland |
US8467875B2 (en) * | 2004-02-12 | 2013-06-18 | Medtronic, Inc. | Stimulation of dorsal genital nerves to treat urologic dysfunctions |
US20080161874A1 (en) * | 2004-02-12 | 2008-07-03 | Ndi Medical, Inc. | Systems and methods for a trial stage and/or long-term treatment of disorders of the body using neurostimulation |
US20050222635A1 (en) * | 2004-03-31 | 2005-10-06 | Krakovsky Alexander A | Potency package two |
DK1759536T3 (en) | 2004-06-01 | 2011-09-05 | Kwalata Trading Ltd | In vitro techniques for use with stem cells |
US9205255B2 (en) | 2004-06-10 | 2015-12-08 | Medtronic Urinary Solutions, Inc. | Implantable pulse generator systems and methods for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue |
US7283867B2 (en) | 2004-06-10 | 2007-10-16 | Ndi Medical, Llc | Implantable system and methods for acquisition and processing of electrical signals from muscles and/or nerves and/or central nervous system tissue |
US7865250B2 (en) * | 2004-06-10 | 2011-01-04 | Medtronic Urinary Solutions, Inc. | Methods for electrical stimulation of nerves in adipose tissue regions |
US8165692B2 (en) | 2004-06-10 | 2012-04-24 | Medtronic Urinary Solutions, Inc. | Implantable pulse generator power management |
US8195304B2 (en) | 2004-06-10 | 2012-06-05 | Medtronic Urinary Solutions, Inc. | Implantable systems and methods for acquisition and processing of electrical signals |
US9308382B2 (en) | 2004-06-10 | 2016-04-12 | Medtronic Urinary Solutions, Inc. | Implantable pulse generator systems and methods for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue |
ATE523221T1 (en) * | 2004-06-10 | 2011-09-15 | Medtronic Urinary Solutions Inc | SYSTEMS AND METHODS FOR THE BILATERAL STIMULATION OF LEFT AND RIGHT BRANCHES OF THE DORSAL GENITAL NERVES FOR THE TREATMENT OF FUNCTIONAL DISORDERS SUCH AS URINARY INCONTINENCE |
US7761167B2 (en) | 2004-06-10 | 2010-07-20 | Medtronic Urinary Solutions, Inc. | Systems and methods for clinician control of stimulation systems |
US7894913B2 (en) * | 2004-06-10 | 2011-02-22 | Medtronic Urinary Solutions, Inc. | Systems and methods of neuromodulation stimulation for the restoration of sexual function |
US20060020297A1 (en) * | 2004-07-20 | 2006-01-26 | Gerber Martin T | Neurostimulation system with distributed stimulators |
US7623924B2 (en) * | 2004-08-31 | 2009-11-24 | Leptos Biomedical, Inc. | Devices and methods for gynecologic hormone modulation in mammals |
US20060110374A1 (en) * | 2004-11-24 | 2006-05-25 | Dudy Czeiger | Method to accelerate stem cell recruitment and homing |
US8277495B2 (en) | 2005-01-13 | 2012-10-02 | Candela Corporation | Method and apparatus for treating a diseased nail |
US8609082B2 (en) | 2005-01-25 | 2013-12-17 | Bio Control Medical Ltd. | Administering bone marrow progenitor cells or myoblasts followed by application of an electrical current for cardiac repair, increasing blood supply or enhancing angiogenesis |
US20060194724A1 (en) * | 2005-02-25 | 2006-08-31 | Whitehurst Todd K | Methods and systems for nerve regeneration |
WO2007038336A2 (en) * | 2005-09-23 | 2007-04-05 | Ellipse Technologies, Inc. | Method and apparatus for adjusting body lumens |
WO2007038567A1 (en) | 2005-09-28 | 2007-04-05 | Candela Corporation | Treating cellulite |
US7747324B2 (en) | 2005-11-10 | 2010-06-29 | Electrocore Llc | Electrical stimulation treatment of bronchial constriction |
US9037247B2 (en) | 2005-11-10 | 2015-05-19 | ElectroCore, LLC | Non-invasive treatment of bronchial constriction |
US8041428B2 (en) | 2006-02-10 | 2011-10-18 | Electrocore Llc | Electrical stimulation treatment of hypotension |
US8812112B2 (en) | 2005-11-10 | 2014-08-19 | ElectroCore, LLC | Electrical treatment of bronchial constriction |
US7725188B2 (en) | 2006-02-10 | 2010-05-25 | Electrocore Llc | Electrical stimulation treatment of hypotension |
US7596414B2 (en) * | 2005-12-05 | 2009-09-29 | Boston Scientific Neuromodulation Corporation | Cuff electrode arrangement for nerve stimulation and methods of treating disorders |
US7610103B2 (en) * | 2005-12-19 | 2009-10-27 | Boston Scientific Neuromodulation Corporation | Electrode arrangement for nerve stimulation and methods of treating disorders |
US7891362B2 (en) | 2005-12-23 | 2011-02-22 | Candela Corporation | Methods for treating pigmentary and vascular abnormalities in a dermal region |
US20070265646A1 (en) * | 2006-01-17 | 2007-11-15 | Ellipse Technologies, Inc. | Dynamically adjustable gastric implants |
CN101400402A (en) | 2006-02-10 | 2009-04-01 | 电子核心公司 | Electrical stimulation treatment of hypotension |
TW200734462A (en) | 2006-03-08 | 2007-09-16 | In Motion Invest Ltd | Regulating stem cells |
US7953498B1 (en) | 2006-03-15 | 2011-05-31 | Boston Scientific Neuromodulation Corporation | Resorbable anchor arrangements for implantable devices and methods of making and using |
US7974706B2 (en) * | 2006-03-30 | 2011-07-05 | Boston Scientific Neuromodulation Corporation | Electrode contact configurations for cuff leads |
US20070255333A1 (en) * | 2006-04-28 | 2007-11-01 | Medtronic, Inc. | Neuromodulation therapy for perineal or dorsal branch of pudendal nerve |
US9480846B2 (en) | 2006-05-17 | 2016-11-01 | Medtronic Urinary Solutions, Inc. | Systems and methods for patient control of stimulation systems |
US8295926B2 (en) | 2006-06-02 | 2012-10-23 | Advanced Neuromodulation Systems, Inc. | Dynamic nerve stimulation in combination with other eating disorder treatment modalities |
US8244377B1 (en) | 2006-09-27 | 2012-08-14 | Boston Scientific Neuromodulation Corporation | Fixation arrangements for implantable leads and methods of making and using |
WO2008058028A2 (en) | 2006-11-03 | 2008-05-15 | Gep Technology, Inc. | Apparatus and methods for minimally invasive obesity treatment |
US8290599B2 (en) * | 2006-12-12 | 2012-10-16 | Boston Scientific Neuromodulation Corporation | Electrode arrangements for tissue stimulation and methods of use and manufacture |
US9339643B1 (en) | 2007-03-30 | 2016-05-17 | Boston Scientific Neuromodulation Corporation | Acutely stiff implantable electrodes |
US20080318314A1 (en) * | 2007-06-20 | 2008-12-25 | Valentin Fulga | Production from blood of cells of neural lineage |
US20090018620A1 (en) * | 2007-07-12 | 2009-01-15 | Pelvipharm | Method for restoring an ejaculatory failure |
US20110009937A1 (en) * | 2007-07-12 | 2011-01-13 | Pelvipharm | Method for restoring an ejaculatory failure |
US20090118777A1 (en) * | 2007-08-09 | 2009-05-07 | Kobi Iki | Efferent and afferent splanchnic nerve stimulation |
US8291914B2 (en) * | 2007-08-17 | 2012-10-23 | Alexander Krakovsky | Phalloplasty process |
US8439845B2 (en) * | 2007-09-25 | 2013-05-14 | Uroval, Inc. | Obtaining measurements of muscle reflexes for diagnosis of patient symptoms |
US7877136B1 (en) | 2007-09-28 | 2011-01-25 | Boston Scientific Neuromodulation Corporation | Enhancement of neural signal transmission through damaged neural tissue via hyperpolarizing electrical stimulation current |
PT2211768T (en) * | 2007-10-11 | 2021-06-29 | Implantica Patent Ltd | Apparatus for controlling flow in a bodily organ |
EP2211768B1 (en) | 2007-10-11 | 2021-03-24 | Implantica Patent Ltd. | Apparatus for controlling flow in a bodily organ |
US8696543B2 (en) | 2007-10-11 | 2014-04-15 | Kirk Promotion Ltd. | Method for controlling flow of intestinal contents in a patient's intestines |
US8992409B2 (en) | 2007-10-11 | 2015-03-31 | Peter Forsell | Method for controlling flow in a bodily organ |
WO2009048376A1 (en) * | 2007-10-11 | 2009-04-16 | Milux Holding Sa | Apparatus for treating impotence |
US8795153B2 (en) | 2007-10-11 | 2014-08-05 | Peter Forsell | Method for treating female sexual dysfunction |
WO2009048400A1 (en) | 2007-10-11 | 2009-04-16 | Milux Holding Sa | Method for controlling flow in a bodily organ |
WO2009048392A1 (en) | 2007-10-11 | 2009-04-16 | Milux Holding Sa | A system, an apparatus, and a method for treating a sexual dysfunctional female patient |
WO2009048382A1 (en) * | 2007-10-11 | 2009-04-16 | Milux Holding Sa | Apparatus for treating female sexual dysfunction |
WO2009048383A1 (en) * | 2007-10-11 | 2009-04-16 | Milux Holding Sa | Apparatus, system and operation method for the treatment of female sexual dysfunction |
EP2244662B1 (en) * | 2008-01-28 | 2021-09-29 | Implantica Patent Ltd. | Blood clot removal device and system |
WO2009096861A1 (en) | 2008-01-29 | 2009-08-06 | Milux Holding Sa | Methods and instruments for treating obesity and gastroesophageal reflux disease |
US8483831B1 (en) | 2008-02-15 | 2013-07-09 | Holaira, Inc. | System and method for bronchial dilation |
EP2529686B1 (en) | 2008-05-09 | 2015-10-14 | Holaira, Inc. | System for treating a bronchial tree |
US8868215B2 (en) | 2008-07-11 | 2014-10-21 | Gep Technology, Inc. | Apparatus and methods for minimally invasive obesity treatment |
EP2349078A4 (en) | 2008-10-10 | 2018-02-07 | Kirk Promotion LTD. | Fastening means for implantable medcial control assembly |
US8874215B2 (en) * | 2008-10-10 | 2014-10-28 | Peter Forsell | System, an apparatus, and a method for treating a sexual dysfunctional female patient |
WO2010042058A1 (en) | 2008-10-10 | 2010-04-15 | Milux Holding S.A. | An improved artificial valve |
EP4282462A3 (en) | 2008-10-10 | 2024-02-21 | MedicalTree Patent Ltd. | Heart help device, system, and method |
WO2010042019A1 (en) | 2008-10-10 | 2010-04-15 | Milux Holding Sa | Heart help device, system, and method |
ES2962384T3 (en) | 2008-10-10 | 2024-03-18 | Implantica Patent Ltd | Device for the treatment of female sexual dysfunction |
US8321030B2 (en) | 2009-04-20 | 2012-11-27 | Advanced Neuromodulation Systems, Inc. | Esophageal activity modulated obesity therapy |
US8340772B2 (en) | 2009-05-08 | 2012-12-25 | Advanced Neuromodulation Systems, Inc. | Brown adipose tissue utilization through neuromodulation |
US9949812B2 (en) | 2009-07-17 | 2018-04-24 | Peter Forsell | Vaginal operation method for the treatment of anal incontinence in women |
US10952836B2 (en) | 2009-07-17 | 2021-03-23 | Peter Forsell | Vaginal operation method for the treatment of urinary incontinence in women |
US9649153B2 (en) | 2009-10-27 | 2017-05-16 | Holaira, Inc. | Delivery devices with coolable energy emitting assemblies |
CA2780608C (en) | 2009-11-11 | 2019-02-26 | Innovative Pulmonary Solutions, Inc. | Systems, apparatuses, and methods for treating tissue and controlling stenosis |
US8911439B2 (en) | 2009-11-11 | 2014-12-16 | Holaira, Inc. | Non-invasive and minimally invasive denervation methods and systems for performing the same |
US8788045B2 (en) | 2010-06-08 | 2014-07-22 | Bluewind Medical Ltd. | Tibial nerve stimulation |
US9457186B2 (en) | 2010-11-15 | 2016-10-04 | Bluewind Medical Ltd. | Bilateral feedback |
US9186504B2 (en) | 2010-11-15 | 2015-11-17 | Rainbow Medical Ltd | Sleep apnea treatment |
WO2013111137A2 (en) | 2012-01-26 | 2013-08-01 | Rainbow Medical Ltd. | Wireless neurqstimulatqrs |
US10173056B2 (en) * | 2012-07-11 | 2019-01-08 | Tel Hashomer Medical Research Infrastructure And Service Ltd. | Methods for improving male fertility |
WO2014087337A1 (en) | 2012-12-06 | 2014-06-12 | Bluewind Medical Ltd. | Delivery of implantable neurostimulators |
US9398933B2 (en) | 2012-12-27 | 2016-07-26 | Holaira, Inc. | Methods for improving drug efficacy including a combination of drug administration and nerve modulation |
US9370660B2 (en) | 2013-03-29 | 2016-06-21 | Rainbow Medical Ltd. | Independently-controlled bidirectional nerve stimulation |
WO2016059542A1 (en) | 2014-10-13 | 2016-04-21 | Ecole Polytechnique Federale De Lausanne (Epfl) | Systems and methods for treating sexual disorders using electro-stimulation |
US9764146B2 (en) | 2015-01-21 | 2017-09-19 | Bluewind Medical Ltd. | Extracorporeal implant controllers |
US9597521B2 (en) | 2015-01-21 | 2017-03-21 | Bluewind Medical Ltd. | Transmitting coils for neurostimulation |
US10004896B2 (en) | 2015-01-21 | 2018-06-26 | Bluewind Medical Ltd. | Anchors and implant devices |
US10376308B2 (en) | 2015-02-05 | 2019-08-13 | Axon Therapies, Inc. | Devices and methods for treatment of heart failure by splanchnic nerve ablation |
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Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4585005A (en) * | 1984-04-06 | 1986-04-29 | Regents Of University Of California | Method and pacemaker for stimulating penile erection |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3403684A (en) * | 1964-11-23 | 1968-10-01 | Ariel I. Stiebel | Electrical stimulator |
GB1434524A (en) * | 1972-04-27 | 1976-05-05 | Nat Res Dev | Urinary control apparatus |
US4406288A (en) * | 1981-04-06 | 1983-09-27 | Hugh P. Cash | Bladder control device and method |
US4542753A (en) * | 1982-12-22 | 1985-09-24 | Biosonics, Inc. | Apparatus and method for stimulating penile erectile tissue |
US4564024A (en) * | 1984-07-02 | 1986-01-14 | Wohler Jr Wilson H | Electro-ejaculator probe |
US5063914A (en) * | 1990-05-30 | 1991-11-12 | Mentor Corporation | Penile prosthesis |
US5199430A (en) * | 1991-03-11 | 1993-04-06 | Case Western Reserve University | Micturitional assist device |
-
1994
- 1994-04-05 US US08/223,160 patent/US5454840A/en not_active Expired - Lifetime
-
1995
- 1995-04-03 WO PCT/US1995/003996 patent/WO1995026783A1/en not_active Application Discontinuation
- 1995-04-03 AU AU22348/95A patent/AU2234895A/en not_active Abandoned
- 1995-04-03 JP JP7525858A patent/JPH09511421A/en not_active Ceased
- 1995-04-03 EP EP95915479A patent/EP0757576A4/en not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4585005A (en) * | 1984-04-06 | 1986-04-29 | Regents Of University Of California | Method and pacemaker for stimulating penile erection |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7702386B2 (en) | 2002-03-22 | 2010-04-20 | Leptos Biomedical, Inc. | Nerve stimulation for treatment of obesity, metabolic syndrome, and Type 2 diabetes |
US7937144B2 (en) | 2002-03-22 | 2011-05-03 | Advanced Neuromodulation Systems, Inc. | Electric modulation of sympathetic nervous system |
US8024035B2 (en) | 2002-03-22 | 2011-09-20 | Advanced Neuromodulation Systems, Inc. | Electric modulation of sympathetic nervous system |
US8838231B2 (en) | 2002-03-22 | 2014-09-16 | Advanced Neuromodulation Systems, Inc. | Neural Stimulation for treatment of metabolic syndrome and type 2 diabetes |
US7689276B2 (en) | 2002-09-13 | 2010-03-30 | Leptos Biomedical, Inc. | Dynamic nerve stimulation for treatment of disorders |
Also Published As
Publication number | Publication date |
---|---|
EP0757576A4 (en) | 1998-02-25 |
AU2234895A (en) | 1995-10-23 |
EP0757576A1 (en) | 1997-02-12 |
JPH09511421A (en) | 1997-11-18 |
US5454840A (en) | 1995-10-03 |
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