WO1995024929A2 - Polymeric gene delivery system - Google Patents
Polymeric gene delivery system Download PDFInfo
- Publication number
- WO1995024929A2 WO1995024929A2 PCT/US1995/003307 US9503307W WO9524929A2 WO 1995024929 A2 WO1995024929 A2 WO 1995024929A2 US 9503307 W US9503307 W US 9503307W WO 9524929 A2 WO9524929 A2 WO 9524929A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polymer
- gene
- cells
- polymeric
- dna
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Fertilizers (AREA)
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95914073A EP0804249A2 (en) | 1994-03-15 | 1995-03-15 | Polymeric gene delivery system |
AU21214/95A AU710504B2 (en) | 1994-03-15 | 1995-03-15 | Polymeric gene delivery system |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21366894A | 1994-03-15 | 1994-03-15 | |
US213,668 | 1994-03-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1995024929A2 true WO1995024929A2 (en) | 1995-09-21 |
WO1995024929A3 WO1995024929A3 (en) | 1995-12-28 |
Family
ID=22796022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1995/003307 WO1995024929A2 (en) | 1994-03-15 | 1995-03-15 | Polymeric gene delivery system |
Country Status (5)
Country | Link |
---|---|
US (4) | US6262034B1 (en) |
EP (1) | EP0804249A2 (en) |
AU (1) | AU710504B2 (en) |
CA (1) | CA2190121A1 (en) |
WO (1) | WO1995024929A2 (en) |
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WO1999029304A1 (en) * | 1997-12-12 | 1999-06-17 | Massachusetts Institute Of Technology | Method for high supercoiled dna content microspheres |
US6004943A (en) * | 1995-11-27 | 1999-12-21 | Inst. Of Biomedical Engineering, Chinese Acdmy Of Med. Science | Protein-coated medical substrates for local delivery of genes and method of forming coatings on the substrates |
WO1999065463A1 (en) * | 1998-06-16 | 1999-12-23 | Ben-Gurion University Of The Negev | Active ingredient delivery systems and devices based on porous matrices |
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US6475779B2 (en) | 2002-11-05 |
US6620617B2 (en) | 2003-09-16 |
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US20010020011A1 (en) | 2001-09-06 |
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