WO1995011720A1 - Impermeable expandable intravascular stent - Google Patents
Impermeable expandable intravascular stent Download PDFInfo
- Publication number
- WO1995011720A1 WO1995011720A1 PCT/US1994/012429 US9412429W WO9511720A1 WO 1995011720 A1 WO1995011720 A1 WO 1995011720A1 US 9412429 W US9412429 W US 9412429W WO 9511720 A1 WO9511720 A1 WO 9511720A1
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- Prior art keywords
- stent
- membrane
- frame
- accordance
- sections
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
Definitions
- This invention relates to intravascular implants for maintaining vascular patency in human blood vessels. More particularly, this invention relates to a radially expandable stent made from a fine wire formed into a serpentine ribbon wound into a cylindrical shape for introduction into a body vessel for balloon expansion therein in a radial fashion to support the wall of the vessel when in the expanded configuration.
- the stent includes an impermeable membrane that lies in the plane of the cylinder.
- This invention is particularly useful in transluminal implantation of a stent for use in the coronary angioplasty to prevent restenosis, and for the treatment of aneurysms or subintimal dissections.
- stents The basic concept of stents has been known for a number of years.
- Various types of stents have been pro ⁇ posed and patented, including self-expanding spring types, compressed spring types, mechanically actuated expandable devices, heat actuated expandable devices, and the like.
- expandable sleeves have been proposed such as shown in Palmaz, U.S. Patent No. 4,733,665.
- a sleeve having slots therethrough to form a permeable mesh. The sleeve is placed transluminally, and then expanded by a balloon catheter through the elastic limit of the metal so as to permanently deform the sleeve into supporting contact with the interior surface of a blood vessel.
- Other examples of expandable wire stents are shown in Hillstead, U.S. Patent No. 4,865,516, and Wiktor, U.S. Patent No. 4, 886,062.
- tissue reac ⁇ tions including thrombus formation, intimal fibropla- sia, and cicatrization could result in restenosis of the vessel.
- Permeable transluminally placed intravascular stents are suboptimum for the treatment of aneurysms. While the structure of the expanded mesh may reduce the pulsatile forces acting against a weakened arterial wall, this effect is doubtless incomplete.
- the art has long utilized grossly impermeable continuous structures such as Teflon grafts and implants for aneurysm repair in larger vessels by conventional open surgical tech ⁇ niques .
- a radially expandable stent for intra- vascular implantation comprising a distensible frame and an impermeable defor able membrane interconnecting por ⁇ tions of the frame to form an impermeable exterior wall.
- the tubular member is dimensioned to receive an inflat ⁇ able catheter for intravascular placement and radial expansion therewith. Expansion of the catheter and the stent brings the wall surface into supporting contact with an interior surface of a vessel.
- the membrane is formed of a synthetic non-latex, non-vinyl polymer, and the frame comprises a fine wire of annealed platinum.
- the membrane extends from end to end of the frame.
- the membrane is disposed on the central portion of the frame, and at least one of the frame ends are not covered by or in contact with the membrane in order to permit anchoring of the ends to the vessel once tissue reaction or remod ⁇ eling of the vessel wall has occurred about the ends of the stent.
- the radially expandable stent comprises a plurality of helically aligned circumferential sections including two end sections and a plurality of intermediate sections that define a cyl ⁇ inder having a longitudinal axis, the cylinder being formed of a continuous wire with the circumferential sections being spaced along the axis in abutting con ⁇ tact.
- Each of the circumferential sections have expand ⁇ able segments that impart radial expandability to the sections, whereby the sections have an unexpanded inser- tion circumference and an expanded implantation circum ⁇ ference that is greater than the insertion circumfer- ence.
- the expandable segments are tear-drop shaped ele ⁇ ments that are alternately inverted about the circumferential sections, each element containing a base and a pair of legs that come together at a common apex when the stent is in an unexpanded condition.
- One of the end sections has a free end or pigtail that is passed back along the circumferential sections and is joined to the other end section to prevent axial expan ⁇ sion of the stent during radial expansion.
- a distensible impermeable membrane formed of a synthetic non-latex, non-vinyl polymer to define a exterior wall surface that contacts an interior surface of a vessel upon radial expansion of the stent.
- the membrane is attached to the frame by placing the frame on.a mandrel; providing a solution of the polymer in an organic solvent such as toluene; dipping the frame and the mandrel into the solution; withdrawing the frame and the mandrel from the solution; thereafter drying the frame and the mandrel; and finally removing the mandrel from the frame.
- the steps of dipping and drying are preferably performed at room temperature.
- Fig. 1 is a side elevation of an unexpanded stent in accordance with the invention supported on a mandrel;
- Fig. 2 is a view similar to Fig. 1 showing the stent mounted about a collapsed balloon catheter insert ⁇ ed in a blood vessel; and Fig. 3 is a view similar to Fig. 3 on a reduced scale showing the expanded stent in position in a blood vessel for holding the blood vessel in an open configu ⁇ ration;
- FIG. 4 is a sectional view through line 4-4 of FIG. 3;
- FIG. 5 is a side elevation similar to FIG. 1 of an unexpanded stent in accordance with an alternate embodiment of the invention;
- FIG. 6 is a sectional view of a diseased blood vessel illustrating the stent of FIG. 5 expanded there- in;
- FIG. 7 is a sectional view through line 7-7 of FIG. 6. DESCRIPTION OF THE PREFERRED EMBODIMENT
- a stent 10 in accordance with the present inven ⁇ tion carried on a mandrel 12 during manufacture.
- a wire frame or sleeve 11 of the stent is formed by first taking a fine wire 14 hav ⁇ ing a diameter of approximately .004", preferably made from platinum, and forming it into a generally sinusoi ⁇ dal form, in which approximately ten cycles or segments per inch are formed in the wire.
- These bends can be formed in any convenient manner, for instance as by bending about a rack gear by running a corresponding spur gear over a wire laid along the rack.
- the next step is to take the wire 14 and to further bend it into a serpentine or figure eight configuration so that the edges of each loop touch and abut the adjacent edges of the next loop forming the tight-looped serpentine ribbon form 16.
- this configuration approximately forty loops per inch of ribbon are present and the height or "amplitude" of the loops is approximately 1/16". This is accomplished by mechanically bending the partially formed loops 18, 18 up against each other into the tear- drop shapes shown in Fig. 1.
- the fine wire 14 used to form the basic flat ribbon 16 is a soft platinum wire that has been fully annealed to remove as much spring memory as possible. The straight wire before bending, being in the fully annealed condition, retains whatever shape it is formed into.
- the flat narrow serpen- tine ribbon 16 is formed, it is wrapped about a mandrel 12 having a diameter of .060" in a spiral or helix fash ⁇ ion with the edges of each helix wrap of the ribbon 16 basically touching the adjacent ribbon helix edges to form the wire sleeve 11.
- the number of convolutions of the helix on the mandrel determines the length of the sleeve 11, and a typical stent of this type may have a length of approximately one and one-half inches.
- the serpentine ribbon 16 of Fig. 2 is wound on the mandrel 12, the pigtail 20 of the wire 14 is inserted through the helix, as may be seen in Fig. 1.
- the ribbon 16 is wound about the mandrel 12 over top of the pigtail 20 of the wire 14.
- the free end of the pigtail 20 extending through the helix is trimmed and welded smoothly to the final turn of the helix so as not to present any increased profile, and so as not to puncture or pierce the balloon catheter or the blood vessel into which it is being inserted.
- the end turn of the helix is welded at 22 and intermediate welds such as 24 are formed to stabilize the length of the helix.
- the first turn of the helix at the other end may also be welded to the pigtail at 26 so that the overall length of the stent can be constrained and maintained in the desired configuration.
- a synthet ⁇ ic polymer membrane 28 is bonded to the sleeve 11 to form an impermeable wall or barrier.
- the membrane 28 should be a hypoallergenic, biologically inert material, that is free of latex rubber proteins and processing chemicals that can cause adverse reactions.
- the material is preferably Tactylon, available from Tactyl Technolo ⁇ gies, Inc., of Vista California.
- the attachment of the polymer membrane 28 to the sleeve 11 is accomplished by dipping the sleeve 11 and the mandrel 12 into a solution of Tactylon in an organic solvent such as toluene at room temperature.
- the solu ⁇ tion permeates the wire sleeve 11, coating the wires thereof.
- the sleeve 11 and mandrel 12 are then withdrawn from the solution and allowed to dry ' at room tempera- ture.
- the polymer forms a membrane 28 that spans the interstices of the sleeve 11, and the result is a continuous impermeable membranous wall that incor ⁇ porates the wire sleeve 11 and covers the gaps and in ⁇ terstices in the sleeve's ribbon and helical substruc- tures.
- the presence of the mandrel 12 during the devel ⁇ opment of the membranous wall assures that the lumen of the sleeve 11 remains patent, and that the ends of the sleeve 11 remain open.
- the final stent 10 is an impermeable wire-reinforced tube or cylinder which is open at each end.
- the stent 10 is used by placing it about the inflatable distal portion of a conventional collapsed balloon catheter 30 as shown in Fig. 2.
- the sleeve 11 generally has a diameter in the neighborhood of 1.5 mm for insertion into the coronary arteries.
- the balloon catheter 30 with the stent 10 mounted thereon is inserted into the appro ⁇ priate blood vessel 40.
- the stent 10 is guided to the desired location where there is an occluding plaque 38 or an aneurysm or other imperfection requiring placement of a stent.
- the membrane 28 presents a smooth surface that gently glides along the intima 42 of the vessel 40, and is unlikely to abrade the endotheli- urn, or create small intimal tears, or otherwise trauma ⁇ tize the plaque 38 so as to produce intramural hemor- rhage.
- the balloon catheter 30 is inflated to radially expand the serpen ⁇ tine wire sleeve 11. As the balloon expands, it expands the tight tear drop bends of the serpentine ribbon 16 as explained in detail in the '483 Patent.
- the stent 10 has been expanded to 4 - 5 mm within the blood vessel 40 as shown in FIG. 3.
- the expanded stent maintains good interior surface support of the blood vessel by maintaining the close spacing of the wire loops and helices forming the sleeve.
- the reinforced impermeable membranous wall 28 is believed to attenuate the pulsa- tile hydraulic forces that are experienced by the seg ⁇ ment of the blood vessel 40 in contact therewith and thereby prevent the enlargement or rupture of an aneu ⁇ rysm.
- the stent 10 is thus particularly suitable for the mechanical stabilization of vascular aneurysms.
- the expanded condition of the stent is shown in
- FIGS. 3 and 4 with the balloon catheter 30 having been removed.
- the stenotic segment is now dilated and the lumen of the vessel 40 is enlarged.
- the impermeable membrane 28 as reinforced by the wire sleeve 11 can prevent the dislodgement and subsequent embolization of fragments of plaque and thrombus that sometimes form in aneurysms.
- the wire pigtail has no sharp ends and the free end is welded to the loop of the helix, there are no sharp edges or points to tear or catch on the catheter balloon or the interior surface of the blood vessel.
- the stent of the present invention can be readily manipulat ⁇ ed to the desired location.
- FIGS. 5 and 6 there is shown an alternate embodiment of a stent 110 in accordance with the ' invention.
- an unexpanded stent 110 is similar to the first embodiment, except now the membrane 128 only forms a wall of a central portion 131 of a wire sleeve 111, and does not extend to end portions 133,
- FIG. 6 there is shown the stent 110 which has been conventionally implanted in a diseased blood vessel 140, and has been in place for a sufficient period for tissue reaction to occur.
- the diseased portion of the vessel 140 is shown as an enlarged segment 141, the diseased condition typically being an aneurysm with a mural thrombus, or a plaque that has now been dilated by the radially expanded stent 110.
- the impermeable mem ⁇ brane 128, reinforced by the wire sleeve 111, is in sealing and stabilizing contact with the intimal surface of the diseased segment 141, and the lumen 143 of the stent 110 is patent, allowing free flow of blood there ⁇ through.
- end portions 133, 133' there are open interstices of the wire sleeve 111, so that contact between the stent 110 and the intimal surface of the vessel 140 is limited to the wire 114.
- This allows a tissue reaction (shown as dark areas 137, 137) to devel ⁇ op about the end portions 133, 133' , and firmly incorpo ⁇ rate the end portions 133, 133' of the stent 110 into the wall of the blood vessel 140.
- the stent 110 is manufactured in much the same way as that of the first embodiment. It is necessary, however to shield the end portions 133, 133' from con ⁇ tact with the non-latex polymer solution. This can be accomplished mechanically by a folded protective sheath or similar. The sheath is removed with the mandrel after drying.
- impermeable membrane is not limited to the particular frame embodiments disclosed herein.
- the membrane can be applied to other frame constructions that are known to the art.
Abstract
There is disclosed a radially expandable stent (100) for intravascular implantation comprising a distensible frame (111) and an impermeable deformable membrane (128) interconnecting portions of the frame to form an impermeable exterior wall. The membrane (128) is formed of a synthetic non-latex, non-vinyl polymer, and the frame (111) comprises a fine wire of annealed platinum. The stent comprises a plurality of helically aligned circumferential sections including two end sections and a plurality of intermediate sections that define a cylinder having a longitudinal axis, the cylinder being formed of a continuous wire with the circumferential sections being spaced along the axis in abutting contact.
Description
IMPERMEABLE EXPANDABLE INTRAVASCULAR STENT BACKGROUND OF THE INVENTION
1. Field of the Invention.
This invention relates to intravascular implants for maintaining vascular patency in human blood vessels. More particularly, this invention relates to a radially expandable stent made from a fine wire formed into a serpentine ribbon wound into a cylindrical shape for introduction into a body vessel for balloon expansion therein in a radial fashion to support the wall of the vessel when in the expanded configuration. The stent includes an impermeable membrane that lies in the plane of the cylinder. This invention is particularly useful in transluminal implantation of a stent for use in the coronary angioplasty to prevent restenosis, and for the treatment of aneurysms or subintimal dissections.
2. Description of the Prior Art.
The basic concept of stents has been known for a number of years. Various types of stents have been pro¬ posed and patented, including self-expanding spring types, compressed spring types, mechanically actuated expandable devices, heat actuated expandable devices, and the like. More recently, expandable sleeves have been proposed such as shown in Palmaz, U.S. Patent No. 4,733,665. In this disclosure there is shown a sleeve having slots therethrough to form a permeable mesh. The sleeve is placed transluminally, and then expanded by a balloon catheter through the elastic limit of the metal so as to permanently deform the sleeve into supporting contact with the interior surface of a blood vessel. Other examples of expandable wire stents are shown in Hillstead, U.S. Patent No. 4,865,516, and Wiktor, U.S. Patent No. 4, 886,062.
In my U.S. Patent No. 5,217,483 (referred to hereinafter as the '483 Patent) I disclose the use of a fine platinum wire bent into a serpentine flat ribbon
which is wound around a mandrel into a radially expand¬ able cylindrical sleeve for mounting on a balloon cathe¬ ter for transluminal intravascular placement. The ex¬ panded sleeve as disposed in a vessel possesses gaps or interstices which are believed to protect the vascular endothelium from contact therewith, and to promote endo- thelial proliferation and remodeling of the vascular intima about the sleeve. However in many cases the trau¬ ma of implantation causes microscopic or even macroscop- ic intimal tears, and exposes the subintimal space to the bloodstream. This is undesirable as further dissec¬ tion of the vessel is possible. Furthermore tissue reac¬ tions, including thrombus formation, intimal fibropla- sia, and cicatrization could result in restenosis of the vessel.
Permeable transluminally placed intravascular stents are suboptimum for the treatment of aneurysms. While the structure of the expanded mesh may reduce the pulsatile forces acting against a weakened arterial wall, this effect is doubtless incomplete. The art has long utilized grossly impermeable continuous structures such as Teflon grafts and implants for aneurysm repair in larger vessels by conventional open surgical tech¬ niques . SUMMARY OF THE INVENTION
It is an object of the present invention to pro¬ vide an improved expandable stent adapted to percutane¬ ous intravascular implantation for supporting the wall of a blood vessel and for stabilizing an aneurysm there- of.
It is another object of the present invention to provide an improved intravascular stent that reduces the rate of restenosis in a vessel subjected to angioplasty therewith. It is yet another object of the present invention to provide an improved expandable stent that can be
percutaneously implanted in a vessel without injury to the vessel.
These and other objects of the present invention are attained by a radially expandable stent for intra- vascular implantation comprising a distensible frame and an impermeable defor able membrane interconnecting por¬ tions of the frame to form an impermeable exterior wall. The tubular member is dimensioned to receive an inflat¬ able catheter for intravascular placement and radial expansion therewith. Expansion of the catheter and the stent brings the wall surface into supporting contact with an interior surface of a vessel.
The membrane is formed of a synthetic non-latex, non-vinyl polymer, and the frame comprises a fine wire of annealed platinum.
According to one aspect of the invention, the membrane extends from end to end of the frame.
In another aspect of the invention the membrane is disposed on the central portion of the frame, and at least one of the frame ends are not covered by or in contact with the membrane in order to permit anchoring of the ends to the vessel once tissue reaction or remod¬ eling of the vessel wall has occurred about the ends of the stent. In a preferred embodiment the radially expandable stent comprises a plurality of helically aligned circumferential sections including two end sections and a plurality of intermediate sections that define a cyl¬ inder having a longitudinal axis, the cylinder being formed of a continuous wire with the circumferential sections being spaced along the axis in abutting con¬ tact. Each of the circumferential sections have expand¬ able segments that impart radial expandability to the sections, whereby the sections have an unexpanded inser- tion circumference and an expanded implantation circum¬ ference that is greater than the insertion circumfer-
ence. The expandable segments are tear-drop shaped ele¬ ments that are alternately inverted about the circumferential sections, each element containing a base and a pair of legs that come together at a common apex when the stent is in an unexpanded condition. One of the end sections has a free end or pigtail that is passed back along the circumferential sections and is joined to the other end section to prevent axial expan¬ sion of the stent during radial expansion. The elements and the circumferential segments are interconnected by a distensible impermeable membrane formed of a synthetic non-latex, non-vinyl polymer to define a exterior wall surface that contacts an interior surface of a vessel upon radial expansion of the stent. In accordance with an aspect of the invention the membrane is attached to the frame by placing the frame on.a mandrel; providing a solution of the polymer in an organic solvent such as toluene; dipping the frame and the mandrel into the solution; withdrawing the frame and the mandrel from the solution; thereafter drying the frame and the mandrel; and finally removing the mandrel from the frame. The steps of dipping and drying are preferably performed at room temperature. BRIEF DESCRIPTION OF THE DRAWING For a better understanding of these and other ob¬ jects of the present invention, reference is made to the detailed description of the invention which is to be read in conjunction with the following drawings, where¬ in: Fig. 1 is a side elevation of an unexpanded stent in accordance with the invention supported on a mandrel;
Fig. 2 is a view similar to Fig. 1 showing the stent mounted about a collapsed balloon catheter insert¬ ed in a blood vessel; and Fig. 3 is a view similar to Fig. 3 on a reduced scale showing the expanded stent in position in a blood
vessel for holding the blood vessel in an open configu¬ ration;
FIG. 4 is a sectional view through line 4-4 of FIG. 3; FIG. 5 is a side elevation similar to FIG. 1 of an unexpanded stent in accordance with an alternate embodiment of the invention;
FIG. 6 is a sectional view of a diseased blood vessel illustrating the stent of FIG. 5 expanded there- in; and
FIG. 7 is a sectional view through line 7-7 of FIG. 6. DESCRIPTION OF THE PREFERRED EMBODIMENT
Turning now to the Drawing, there is shown in FIG. 1 a stent 10 in accordance with the present inven¬ tion carried on a mandrel 12 during manufacture. As taught in the '483 Patent, a wire frame or sleeve 11 of the stent is formed by first taking a fine wire 14 hav¬ ing a diameter of approximately .004", preferably made from platinum, and forming it into a generally sinusoi¬ dal form, in which approximately ten cycles or segments per inch are formed in the wire. These bends can be formed in any convenient manner, for instance as by bending about a rack gear by running a corresponding spur gear over a wire laid along the rack. The next step is to take the wire 14 and to further bend it into a serpentine or figure eight configuration so that the edges of each loop touch and abut the adjacent edges of the next loop forming the tight-looped serpentine ribbon form 16. In this configuration, approximately forty loops per inch of ribbon are present and the height or "amplitude" of the loops is approximately 1/16". This is accomplished by mechanically bending the partially formed loops 18, 18 up against each other into the tear- drop shapes shown in Fig. 1. The fine wire 14 used to form the basic flat ribbon 16 is a soft platinum wire
that has been fully annealed to remove as much spring memory as possible. The straight wire before bending, being in the fully annealed condition, retains whatever shape it is formed into. After the flat narrow serpen- tine ribbon 16 is formed, it is wrapped about a mandrel 12 having a diameter of .060" in a spiral or helix fash¬ ion with the edges of each helix wrap of the ribbon 16 basically touching the adjacent ribbon helix edges to form the wire sleeve 11. The number of convolutions of the helix on the mandrel determines the length of the sleeve 11, and a typical stent of this type may have a length of approximately one and one-half inches. As the serpentine ribbon 16 of Fig. 2 is wound on the mandrel 12, the pigtail 20 of the wire 14 is inserted through the helix, as may be seen in Fig. 1. In actual practice, the ribbon 16 is wound about the mandrel 12 over top of the pigtail 20 of the wire 14. After the helix is formed to the desired length, the free end of the pigtail 20 extending through the helix is trimmed and welded smoothly to the final turn of the helix so as not to present any increased profile, and so as not to puncture or pierce the balloon catheter or the blood vessel into which it is being inserted. The end turn of the helix is welded at 22 and intermediate welds such as 24 are formed to stabilize the length of the helix. The first turn of the helix at the other end may also be welded to the pigtail at 26 so that the overall length of the stent can be constrained and maintained in the desired configuration. After formation of the wire sleeve 11, a synthet¬ ic polymer membrane 28 is bonded to the sleeve 11 to form an impermeable wall or barrier. The membrane 28 should be a hypoallergenic, biologically inert material, that is free of latex rubber proteins and processing chemicals that can cause adverse reactions. The material
is preferably Tactylon, available from Tactyl Technolo¬ gies, Inc., of Vista California.
The attachment of the polymer membrane 28 to the sleeve 11 is accomplished by dipping the sleeve 11 and the mandrel 12 into a solution of Tactylon in an organic solvent such as toluene at room temperature. The solu¬ tion permeates the wire sleeve 11, coating the wires thereof. The sleeve 11 and mandrel 12 are then withdrawn from the solution and allowed to dry 'at room tempera- ture. During drying the polymer forms a membrane 28 that spans the interstices of the sleeve 11, and the result is a continuous impermeable membranous wall that incor¬ porates the wire sleeve 11 and covers the gaps and in¬ terstices in the sleeve's ribbon and helical substruc- tures. The presence of the mandrel 12 during the devel¬ opment of the membranous wall assures that the lumen of the sleeve 11 remains patent, and that the ends of the sleeve 11 remain open. When the mandrel 12 is removed, the final stent 10 is an impermeable wire-reinforced tube or cylinder which is open at each end.
The stent 10 is used by placing it about the inflatable distal portion of a conventional collapsed balloon catheter 30 as shown in Fig. 2. In this configu¬ ration, the sleeve 11 generally has a diameter in the neighborhood of 1.5 mm for insertion into the coronary arteries. In a known manner the balloon catheter 30 with the stent 10 mounted thereon is inserted into the appro¬ priate blood vessel 40. The stent 10 is guided to the desired location where there is an occluding plaque 38 or an aneurysm or other imperfection requiring placement of a stent. As the stent is passed through a stenotic segment of the vessel 40, the membrane 28 presents a smooth surface that gently glides along the intima 42 of the vessel 40, and is unlikely to abrade the endotheli- urn, or create small intimal tears, or otherwise trauma¬ tize the plaque 38 so as to produce intramural hemor-
rhage. Once the stent 10 is properly located and veri¬ fied by fluoroscopic or other technique, the balloon catheter 30 is inflated to radially expand the serpen¬ tine wire sleeve 11. As the balloon expands, it expands the tight tear drop bends of the serpentine ribbon 16 as explained in detail in the '483 Patent. For instance, in a particular embodiment where the diameter of the stent on the collapsed balloon catheter was 1.5 mm, the stent 10 has been expanded to 4 - 5 mm within the blood vessel 40 as shown in FIG. 3. The expanded stent maintains good interior surface support of the blood vessel by maintaining the close spacing of the wire loops and helices forming the sleeve. The reinforced impermeable membranous wall 28 is believed to attenuate the pulsa- tile hydraulic forces that are experienced by the seg¬ ment of the blood vessel 40 in contact therewith and thereby prevent the enlargement or rupture of an aneu¬ rysm. The stent 10 is thus particularly suitable for the mechanical stabilization of vascular aneurysms. The expanded condition of the stent is shown in
FIGS. 3 and 4 with the balloon catheter 30 having been removed. The stenotic segment is now dilated and the lumen of the vessel 40 is enlarged. In a case where the abnormal segment of the vessel 40 has an aneurysm, it is believed that the impermeable membrane 28 as reinforced by the wire sleeve 11 can prevent the dislodgement and subsequent embolization of fragments of plaque and thrombus that sometimes form in aneurysms. Also since the wire pigtail has no sharp ends and the free end is welded to the loop of the helix, there are no sharp edges or points to tear or catch on the catheter balloon or the interior surface of the blood vessel. Thus the stent of the present invention can be readily manipulat¬ ed to the desired location. In prior art devices where the necessary surface support had to be achieved by heavier wire or a denser sleeve, it became difficult to
flex the sleeve so as to transit the convoluted blood vessels. When a looser wire configuration was employed, the stability of the stent was decreased and the ulti¬ mate efficacy of the implanted stent compromised. Turning now to FIGS. 5 and 6, there is shown an alternate embodiment of a stent 110 in accordance with the ' invention. In FIG. 5 an unexpanded stent 110 is similar to the first embodiment, except now the membrane 128 only forms a wall of a central portion 131 of a wire sleeve 111, and does not extend to end portions 133,
133' . In FIG. 6 there is shown the stent 110 which has been conventionally implanted in a diseased blood vessel 140, and has been in place for a sufficient period for tissue reaction to occur. The diseased portion of the vessel 140 is shown as an enlarged segment 141, the diseased condition typically being an aneurysm with a mural thrombus, or a plaque that has now been dilated by the radially expanded stent 110. The impermeable mem¬ brane 128, reinforced by the wire sleeve 111, is in sealing and stabilizing contact with the intimal surface of the diseased segment 141, and the lumen 143 of the stent 110 is patent, allowing free flow of blood there¬ through. In the end portions 133, 133' there are open interstices of the wire sleeve 111, so that contact between the stent 110 and the intimal surface of the vessel 140 is limited to the wire 114. This allows a tissue reaction (shown as dark areas 137, 137) to devel¬ op about the end portions 133, 133' , and firmly incorpo¬ rate the end portions 133, 133' of the stent 110 into the wall of the blood vessel 140.
The stent 110 is manufactured in much the same way as that of the first embodiment. It is necessary, however to shield the end portions 133, 133' from con¬ tact with the non-latex polymer solution. This can be accomplished mechanically by a folded protective sheath
or similar. The sheath is removed with the mandrel after drying.
It will be understood that the benefits of the impermeable membrane are not limited to the particular frame embodiments disclosed herein. The membrane can be applied to other frame constructions that are known to the art.
While this invention has been explained with reference to the structure disclosed herein, it is not confined to the details set forth and this application is intended to cover any modifications and changes as may come within the scope of the following claims:
Claims
What is claimed is: 1. A radially expandable stent for intravascular im- plantation comprising: a tubular structure having a longitudinal axis, a radius, a central portion, and first and second ends, said tubular structure comprising a distensi- ble frame and an impermeable deformable membrane interconnecting portions of said frame to form an impermeable wall surface disposed between said first and second ends about said axis, said tubular struc- ture being adapted to receive an inflatable catheter for intravascular placement and radial expansion therewith; whereby expansion of said catheter and said tubular structure brings said wall surface into supporting contact with an interior surface of a vessel.
2. The stent in accordance with claim 1, wherein said membrane comprises a synthetic non-latex, non-vinyl polymer.
3. The stent in accordance with claim 1, wherein said frame comprises a fine wire.
4. The stent in accordance with claim 1, wherein said membrane extends from said first end to said second end.
5. The stent in accordance with claim 1, wherein said membrane is disposed on said central portion and at least one of said first end and said second end is not in contact with said membrane.
6. The stent in accordance with claim 5, wherein nei- ther said first end nor said second end is in contact with said membrane.
7. A radially expandable stent for intravascular im- plantation comprising: a plurality of helically aligned circumferential sec- tions including two end sections and a plurality of intermediate sections that define a cylinder having a longitudinal axis, said cylinder being formed of a continuous wire with said circumferential sections being spaced along said axis in abutting contact; each of said circumferential sections having expandable segments that impart radial expandability to said sections whereby said sections have an unexpanded insertion circumference and an expanded implantation circumference that is greater than said insertion circumference; said expandable segments being tear-drop shaped elements that are alternately inverted about said circumferential sections, each element containing a base and a pair of legs that come together at a common apex when the stent is in an unexpanded con- dition; and one of said end sections having a free end that is passed back along the circumferential sections and is joined to the other end section to prevent axial expansion of the stent during radial expansion; said elements and said circumferential segments being interconnected by a distensible impermeable membrane to form a wall surface that contacts an interior surface of a vessel upon radial expansion of the stent.
8. The stent in accordance with claim 7, wherein said membrane comprises a synthetic non-latex, non-vinyl polymer.
9. The stent of claim 7 wherein the wire forming the cylinder is annealed.
10. The stent of claim 7 wherein the wire forming the cylinder is annealed platinum.
11. The stent in accordance with claim 7, wherein said membrane extends from said first end to said second end.
12. The stent in accordance with claim 7, wherein said membrane is disposed on said central portion and at least one of said first end and said second end is not in contact with said membrane.
13. A method of forming a radially expandable stent for transluminal implantation within a body vessel compris- ing the steps of: providing a tubular structure having a lumen and frame members defining a plurality of interstices therebe- tween, said frame being dimensioned to be carried by an expandable intravascular catheter that is re- ceived in said lumen; attaching a deformable membrane to said frame to form a tubular outer wall that covers said interstices to prevent fluid and tissue communication therethrough, said membrane comprising a synthetic non-latex, non- vinyl polymer.
14. The method in accordance with claim 13, wherein said step of attaching is performed by the steps of: placing said frame on a mandrel; providing a solution of said polymer in an organic sol- vent; dipping said frame and said mandrel into said solution; withdrawing said frame and said mandrel from said solu- tion; thereafter drying said frame and said mandrel; and removing said mandrel from said frame.
15. The method in accordance with claim 13, wherein said step of dipping and drying are performed at room temper- ature.
16. The method in accordance with claim 13, wherein said organic solvent is toluene.
17. The method in accordance with claim 13, wherein said step of providing a frame is performed by the steps of: forming a continuous length of fine wire into a first sinusoidal ribbon having a straight pigtail; compacting said sinusoidal ribbon into a flat serpentine ribbon having adjacent loops touching one another,- placing said straight pigtail along a cylindrical man- drel; winding said flat serpentine ribbon about said cylindri- cal mandrel and pigtail to form a helical sleeve; trimming the end of said pigtail to match the end of said helical sleeve; and welding said trimmed pigtail end to the end of the sleeve.
18. The method in accordance with claim 13, wherein said membrane extends from a first free end to a second free end of said frame.
19. The stent in accordance with claim 13, wherein said membrane is disposed on a central portion of said frame and at least one of a first free end and a second free end is not in contact with said membrane.
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Application Number | Priority Date | Filing Date | Title |
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US08/145,435 | 1993-10-29 | ||
US08/145,435 US5389106A (en) | 1993-10-29 | 1993-10-29 | Impermeable expandable intravascular stent |
Publications (1)
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WO1995011720A1 true WO1995011720A1 (en) | 1995-05-04 |
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Application Number | Title | Priority Date | Filing Date |
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PCT/US1994/012429 WO1995011720A1 (en) | 1993-10-29 | 1994-10-28 | Impermeable expandable intravascular stent |
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WO (1) | WO1995011720A1 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8267989B2 (en) | 2004-01-30 | 2012-09-18 | Trivascular, Inc. | Inflatable porous implants and methods for drug delivery |
US9867727B2 (en) | 1998-02-09 | 2018-01-16 | Trivascular, Inc. | Endovascular graft |
US11166811B2 (en) | 2018-03-02 | 2021-11-09 | James Yashu Coe | Transcatheter valve |
Families Citing this family (491)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7101392B2 (en) * | 1992-03-31 | 2006-09-05 | Boston Scientific Corporation | Tubular medical endoprostheses |
JPH07505316A (en) | 1992-03-31 | 1995-06-15 | ボストン サイエンティフィック コーポレーション | medical wire |
US6277084B1 (en) | 1992-03-31 | 2001-08-21 | Boston Scientific Corporation | Ultrasonic medical device |
USD380831S (en) * | 1992-08-06 | 1997-07-08 | William Cook Europe A/S | Implantable self-expanding stent |
US5630840A (en) | 1993-01-19 | 1997-05-20 | Schneider (Usa) Inc | Clad composite stent |
WO1994016646A1 (en) * | 1993-01-19 | 1994-08-04 | Schneider (Usa) Inc. | Clad composite stent |
US20050059889A1 (en) * | 1996-10-16 | 2005-03-17 | Schneider (Usa) Inc., A Minnesota Corporation | Clad composite stent |
ES2114964T3 (en) | 1993-04-23 | 1998-06-16 | Schneider Europ Ag | ENDOPROTESIS WITH A COAT OF ELASTIC MATERIAL COATING AND METHOD FOR APPLYING THE COAT ON ENDOPROTESIS. |
US6689158B1 (en) * | 1993-09-30 | 2004-02-10 | Endogad Research Pty Limited | Intraluminal graft |
US5782904A (en) | 1993-09-30 | 1998-07-21 | Endogad Research Pty Limited | Intraluminal graft |
US6165213A (en) * | 1994-02-09 | 2000-12-26 | Boston Scientific Technology, Inc. | System and method for assembling an endoluminal prosthesis |
US5609627A (en) * | 1994-02-09 | 1997-03-11 | Boston Scientific Technology, Inc. | Method for delivering a bifurcated endoluminal prosthesis |
US6051020A (en) * | 1994-02-09 | 2000-04-18 | Boston Scientific Technology, Inc. | Bifurcated endoluminal prosthesis |
US6039749A (en) | 1994-02-10 | 2000-03-21 | Endovascular Systems, Inc. | Method and apparatus for deploying non-circular stents and graftstent complexes |
CA2188563C (en) * | 1994-04-29 | 2005-08-02 | Andrew W. Buirge | Stent with collagen |
EP0858298A4 (en) | 1994-04-29 | 1999-04-07 | Boston Scient Corp | Medical prosthetic stent and method of manufacture |
JPH10506291A (en) | 1994-05-06 | 1998-06-23 | エンドームド・インコーポレーテッド | Radially expandable polytetrafluoroethylene |
DE29522101U1 (en) | 1994-06-08 | 1999-12-09 | Cardiovascular Concepts Inc | Endoluminal prosthesis |
EP1582181A3 (en) * | 1994-06-27 | 2010-04-21 | Bard Peripheral Vascular, Inc. | Radially expandable polytetrafluoroethylene and expandable endovascular stents formed therewith |
US20020156523A1 (en) * | 1994-08-31 | 2002-10-24 | Lilip Lau | Exterior supported self-expanding stent-graft |
US6331188B1 (en) * | 1994-08-31 | 2001-12-18 | Gore Enterprise Holdings, Inc. | Exterior supported self-expanding stent-graft |
US5591230A (en) * | 1994-09-07 | 1997-01-07 | Global Therapeutics, Inc. | Radially expandable stent |
US6015429A (en) * | 1994-09-08 | 2000-01-18 | Gore Enterprise Holdings, Inc. | Procedures for introducing stents and stent-grafts |
US5637113A (en) * | 1994-12-13 | 1997-06-10 | Advanced Cardiovascular Systems, Inc. | Polymer film for wrapping a stent structure |
USD380266S (en) * | 1994-12-30 | 1997-06-24 | Cook Incorporated | Implantable, actively expandable stent |
US5591226A (en) * | 1995-01-23 | 1997-01-07 | Schneider (Usa) Inc. | Percutaneous stent-graft and method for delivery thereof |
EP0810845A2 (en) * | 1995-02-22 | 1997-12-10 | Menlo Care Inc. | Covered expanding mesh stent |
US20070073384A1 (en) * | 1995-03-01 | 2007-03-29 | Boston Scientific Scimed, Inc. | Longitudinally flexible expandable stent |
US7204848B1 (en) | 1995-03-01 | 2007-04-17 | Boston Scientific Scimed, Inc. | Longitudinally flexible expandable stent |
US6818014B2 (en) | 1995-03-01 | 2004-11-16 | Scimed Life Systems, Inc. | Longitudinally flexible expandable stent |
DE69622231T2 (en) | 1995-03-01 | 2002-12-05 | Scimed Life Systems Inc | LENGTHFLEXIBLE AND EXPANDABLE STENT |
US6039755A (en) * | 1997-02-05 | 2000-03-21 | Impra, Inc., A Division Of C.R. Bard, Inc. | Radially expandable tubular polytetrafluoroethylene grafts and method of making same |
US6579314B1 (en) * | 1995-03-10 | 2003-06-17 | C.R. Bard, Inc. | Covered stent with encapsulated ends |
US6451047B2 (en) | 1995-03-10 | 2002-09-17 | Impra, Inc. | Encapsulated intraluminal stent-graft and methods of making same |
US6124523A (en) * | 1995-03-10 | 2000-09-26 | Impra, Inc. | Encapsulated stent |
US6264684B1 (en) | 1995-03-10 | 2001-07-24 | Impra, Inc., A Subsidiary Of C.R. Bard, Inc. | Helically supported graft |
JP3507503B2 (en) * | 1995-03-10 | 2004-03-15 | インプラ・インコーポレーテッド | Sealable stent for body cavity, method for producing the same, and method for introducing the same into body cavity |
US5807398A (en) * | 1995-04-28 | 1998-09-15 | Shaknovich; Alexander | Shuttle stent delivery catheter |
KR100452916B1 (en) * | 1995-07-25 | 2005-05-27 | 메드스텐트 인코퍼레이티드 | Expandible Stent |
US6261318B1 (en) | 1995-07-25 | 2001-07-17 | Medstent Inc. | Expandable stent |
WO1997007751A1 (en) | 1995-08-24 | 1997-03-06 | Impra, Inc. | Covered endoluminal stent and method of assembly |
US5758562A (en) * | 1995-10-11 | 1998-06-02 | Schneider (Usa) Inc. | Process for manufacturing braided composite prosthesis |
US5776161A (en) | 1995-10-16 | 1998-07-07 | Instent, Inc. | Medical stents, apparatus and method for making same |
US6287336B1 (en) | 1995-10-16 | 2001-09-11 | Medtronic, Inc. | Variable flexibility stent |
WO1997014375A1 (en) * | 1995-10-20 | 1997-04-24 | Bandula Wijay | Vascular stent |
US5669924A (en) * | 1995-10-26 | 1997-09-23 | Shaknovich; Alexander | Y-shuttle stent assembly for bifurcating vessels and method of using the same |
US5913896A (en) * | 1995-11-28 | 1999-06-22 | Medtronic, Inc. | Interwoven dual sinusoidal helix stent |
US5741293A (en) * | 1995-11-28 | 1998-04-21 | Wijay; Bandula | Locking stent |
US6203569B1 (en) | 1996-01-04 | 2001-03-20 | Bandula Wijay | Flexible stent |
US6428571B1 (en) | 1996-01-22 | 2002-08-06 | Scimed Life Systems, Inc. | Self-sealing PTFE vascular graft and manufacturing methods |
US5800512A (en) * | 1996-01-22 | 1998-09-01 | Meadox Medicals, Inc. | PTFE vascular graft |
US5980553A (en) * | 1996-12-20 | 1999-11-09 | Cordis Corporation | Axially flexible stent |
US5895406A (en) * | 1996-01-26 | 1999-04-20 | Cordis Corporation | Axially flexible stent |
US5938682A (en) * | 1996-01-26 | 1999-08-17 | Cordis Corporation | Axially flexible stent |
US6258116B1 (en) | 1996-01-26 | 2001-07-10 | Cordis Corporation | Bifurcated axially flexible stent |
JPH09215753A (en) * | 1996-02-08 | 1997-08-19 | Schneider Usa Inc | Self-expanding stent made of titanium alloy |
US5707387A (en) * | 1996-03-25 | 1998-01-13 | Wijay; Bandula | Flexible stent |
US5725548A (en) * | 1996-04-08 | 1998-03-10 | Iowa India Investments Company Limited | Self-locking stent and method for its production |
US5713949A (en) * | 1996-08-06 | 1998-02-03 | Jayaraman; Swaminathan | Microporous covered stents and method of coating |
AU2778497A (en) * | 1996-04-24 | 1997-11-12 | Legona Anstalt | Endoprothesis intended to be set in place into a body channel |
FR2747912B1 (en) * | 1996-04-24 | 1999-01-22 | Legona Anstalt | INTRACORPOREAL STENT TO BE PLACED IN A BODY CHANNEL |
JP4636634B2 (en) * | 1996-04-26 | 2011-02-23 | ボストン サイエンティフィック サイムド,インコーポレイテッド | Intravascular stent |
US6241760B1 (en) * | 1996-04-26 | 2001-06-05 | G. David Jang | Intravascular stent |
US6152957A (en) * | 1996-04-26 | 2000-11-28 | Jang; G. David | Intravascular stent |
US6235053B1 (en) * | 1998-02-02 | 2001-05-22 | G. David Jang | Tubular stent consists of chevron-shape expansion struts and contralaterally attached diagonal connectors |
US20040106985A1 (en) * | 1996-04-26 | 2004-06-03 | Jang G. David | Intravascular stent |
US6006134A (en) * | 1998-04-30 | 1999-12-21 | Medtronic, Inc. | Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers |
US5891191A (en) * | 1996-04-30 | 1999-04-06 | Schneider (Usa) Inc | Cobalt-chromium-molybdenum alloy stent and stent-graft |
US5718159A (en) * | 1996-04-30 | 1998-02-17 | Schneider (Usa) Inc. | Process for manufacturing three-dimensional braided covered stent |
US6592617B2 (en) * | 1996-04-30 | 2003-07-15 | Boston Scientific Scimed, Inc. | Three-dimensional braided covered stent |
US5928279A (en) | 1996-07-03 | 1999-07-27 | Baxter International Inc. | Stented, radially expandable, tubular PTFE grafts |
US5980514A (en) | 1996-07-26 | 1999-11-09 | Target Therapeutics, Inc. | Aneurysm closure device assembly |
EP0934035B8 (en) | 1996-09-26 | 2006-01-18 | Boston Scientific Scimed, Inc. | Support structure/membrane composite medical device |
US5824046A (en) * | 1996-09-27 | 1998-10-20 | Scimed Life Systems, Inc. | Covered stent |
US6010529A (en) * | 1996-12-03 | 2000-01-04 | Atrium Medical Corporation | Expandable shielded vessel support |
US5925074A (en) * | 1996-12-03 | 1999-07-20 | Atrium Medical Corporation | Vascular endoprosthesis and method |
US6551350B1 (en) * | 1996-12-23 | 2003-04-22 | Gore Enterprise Holdings, Inc. | Kink resistant bifurcated prosthesis |
US6352561B1 (en) * | 1996-12-23 | 2002-03-05 | W. L. Gore & Associates | Implant deployment apparatus |
US6117168A (en) | 1996-12-31 | 2000-09-12 | Scimed Life Systems, Inc. | Multilayer liquid absorption and deformation devices |
US5843166A (en) * | 1997-01-17 | 1998-12-01 | Meadox Medicals, Inc. | Composite graft-stent having pockets for accomodating movement |
US5961545A (en) * | 1997-01-17 | 1999-10-05 | Meadox Medicals, Inc. | EPTFE graft-stent composite device |
US5899934A (en) * | 1997-01-31 | 1999-05-04 | Medtronic, Inc | Dual stent |
EP1011529B1 (en) * | 1997-03-05 | 2005-01-26 | Boston Scientific Limited | Conformal laminate stent device |
US5843168A (en) * | 1997-03-31 | 1998-12-01 | Medtronic, Inc. | Double wave stent with strut |
US6240616B1 (en) * | 1997-04-15 | 2001-06-05 | Advanced Cardiovascular Systems, Inc. | Method of manufacturing a medicated porous metal prosthesis |
US10028851B2 (en) * | 1997-04-15 | 2018-07-24 | Advanced Cardiovascular Systems, Inc. | Coatings for controlling erosion of a substrate of an implantable medical device |
US8172897B2 (en) * | 1997-04-15 | 2012-05-08 | Advanced Cardiovascular Systems, Inc. | Polymer and metal composite implantable medical devices |
US5860966A (en) * | 1997-04-16 | 1999-01-19 | Numed, Inc. | Method of securing a stent on a balloon catheter |
US6776792B1 (en) * | 1997-04-24 | 2004-08-17 | Advanced Cardiovascular Systems Inc. | Coated endovascular stent |
US6070589A (en) | 1997-08-01 | 2000-06-06 | Teramed, Inc. | Methods for deploying bypass graft stents |
US5824059A (en) * | 1997-08-05 | 1998-10-20 | Wijay; Bandula | Flexible stent |
US6746476B1 (en) * | 1997-09-22 | 2004-06-08 | Cordis Corporation | Bifurcated axially flexible stent |
US5948016A (en) * | 1997-09-25 | 1999-09-07 | Jang; G. David | Intravascular stent with non-parallel slots |
US20050154446A1 (en) * | 1998-01-26 | 2005-07-14 | Peter Phillips | Reinforced graft |
US7520890B2 (en) * | 1998-01-26 | 2009-04-21 | Phillips Peter W | Reinforced graft and method of deployment |
AU737035B2 (en) | 1998-01-26 | 2001-08-09 | Anson Medical Limited | Reinforced graft |
US6533807B2 (en) * | 1998-02-05 | 2003-03-18 | Medtronic, Inc. | Radially-expandable stent and delivery system |
US6488701B1 (en) | 1998-03-31 | 2002-12-03 | Medtronic Ave, Inc. | Stent-graft assembly with thin-walled graft component and method of manufacture |
ES2212821T3 (en) | 1998-03-26 | 2004-08-01 | Biomat B.V. | ENDOVASCULAR EXTENSORS WITH POLYMER COATING. |
US6290731B1 (en) | 1998-03-30 | 2001-09-18 | Cordis Corporation | Aortic graft having a precursor gasket for repairing an abdominal aortic aneurysm |
US6626938B1 (en) * | 2000-11-16 | 2003-09-30 | Cordis Corporation | Stent graft having a pleated graft member |
US8029561B1 (en) | 2000-05-12 | 2011-10-04 | Cordis Corporation | Drug combination useful for prevention of restenosis |
US6099559A (en) * | 1998-05-28 | 2000-08-08 | Medtronic Ave, Inc. | Endoluminal support assembly with capped ends |
US6143022A (en) * | 1998-08-24 | 2000-11-07 | Medtronic Ave, Inc. | Stent-graft assembly with dual configuration graft component and method of manufacture |
EP1117348B1 (en) | 1998-09-30 | 2006-11-02 | Bard Peripheral Vascular, Inc. | Selective adherence of stent-graft coverings, mandrel and method of making stent-graft device |
US6547814B2 (en) | 1998-09-30 | 2003-04-15 | Impra, Inc. | Selective adherence of stent-graft coverings |
EP1128783A1 (en) * | 1998-11-09 | 2001-09-05 | Mivi Technologies Inc. | Expandable stent and method for manufacturing same |
US6190403B1 (en) | 1998-11-13 | 2001-02-20 | Cordis Corporation | Low profile radiopaque stent with increased longitudinal flexibility and radial rigidity |
US6340366B2 (en) | 1998-12-08 | 2002-01-22 | Bandula Wijay | Stent with nested or overlapping rings |
WO2000042949A2 (en) * | 1999-01-22 | 2000-07-27 | Gore Enterprise Holdings, Inc. | A biliary stent-graft |
DK1148839T3 (en) | 1999-02-01 | 2008-12-15 | Univ Texas | Woven two-branched and three-branched stents and methods of making them |
US7018401B1 (en) * | 1999-02-01 | 2006-03-28 | Board Of Regents, The University Of Texas System | Woven intravascular devices and methods for making the same and apparatus for delivery of the same |
US6558414B2 (en) | 1999-02-02 | 2003-05-06 | Impra, Inc. | Partial encapsulation of stents using strips and bands |
US6398803B1 (en) * | 1999-02-02 | 2002-06-04 | Impra, Inc., A Subsidiary Of C.R. Bard, Inc. | Partial encapsulation of stents |
US6287333B1 (en) | 1999-03-15 | 2001-09-11 | Angiodynamics, Inc. | Flexible stent |
US6364903B2 (en) | 1999-03-19 | 2002-04-02 | Meadox Medicals, Inc. | Polymer coated stent |
US6730116B1 (en) * | 1999-04-16 | 2004-05-04 | Medtronic, Inc. | Medical device for intraluminal endovascular stenting |
US6464723B1 (en) | 1999-04-22 | 2002-10-15 | Advanced Cardiovascular Systems, Inc. | Radiopaque stents |
US6673103B1 (en) * | 1999-05-20 | 2004-01-06 | Scimed Life Systems, Inc. | Mesh and stent for increased flexibility |
EP1057459A1 (en) | 1999-06-01 | 2000-12-06 | Numed, Inc. | Radially expandable stent |
US6652570B2 (en) | 1999-07-02 | 2003-11-25 | Scimed Life Systems, Inc. | Composite vascular graft |
US6364904B1 (en) * | 1999-07-02 | 2002-04-02 | Scimed Life Systems, Inc. | Helically formed stent/graft assembly |
US20010018609A1 (en) * | 1999-08-11 | 2001-08-30 | Scott Smith | Seamless braided or spun stent cover |
US6790228B2 (en) * | 1999-12-23 | 2004-09-14 | Advanced Cardiovascular Systems, Inc. | Coating for implantable devices and a method of forming the same |
US6585757B1 (en) | 1999-09-15 | 2003-07-01 | Advanced Cardiovascular Systems, Inc. | Endovascular stent with radiopaque spine |
US6334868B1 (en) | 1999-10-08 | 2002-01-01 | Advanced Cardiovascular Systems, Inc. | Stent cover |
US6331189B1 (en) | 1999-10-18 | 2001-12-18 | Medtronic, Inc. | Flexible medical stent |
US6475235B1 (en) | 1999-11-16 | 2002-11-05 | Iowa-India Investments Company, Limited | Encapsulated stent preform |
US8016877B2 (en) * | 1999-11-17 | 2011-09-13 | Medtronic Corevalve Llc | Prosthetic valve for transluminal delivery |
US8579966B2 (en) | 1999-11-17 | 2013-11-12 | Medtronic Corevalve Llc | Prosthetic valve for transluminal delivery |
US20070043435A1 (en) * | 1999-11-17 | 2007-02-22 | Jacques Seguin | Non-cylindrical prosthetic valve system for transluminal delivery |
US7018406B2 (en) | 1999-11-17 | 2006-03-28 | Corevalve Sa | Prosthetic valve for transluminal delivery |
US20010053931A1 (en) * | 1999-11-24 | 2001-12-20 | Salvatore J. Abbruzzese | Thin-layered, endovascular silk-covered stent device and method of manufacture thereof |
US6602287B1 (en) | 1999-12-08 | 2003-08-05 | Advanced Cardiovascular Systems, Inc. | Stent with anti-thrombogenic coating |
US8241274B2 (en) | 2000-01-19 | 2012-08-14 | Medtronic, Inc. | Method for guiding a medical device |
US6613082B2 (en) | 2000-03-13 | 2003-09-02 | Jun Yang | Stent having cover with drug delivery capability |
US6379382B1 (en) | 2000-03-13 | 2002-04-30 | Jun Yang | Stent having cover with drug delivery capability |
US7875283B2 (en) * | 2000-04-13 | 2011-01-25 | Advanced Cardiovascular Systems, Inc. | Biodegradable polymers for use with implantable medical devices |
US6527801B1 (en) * | 2000-04-13 | 2003-03-04 | Advanced Cardiovascular Systems, Inc. | Biodegradable drug delivery material for stent |
US8109994B2 (en) | 2003-01-10 | 2012-02-07 | Abbott Cardiovascular Systems, Inc. | Biodegradable drug delivery material for stent |
WO2001085030A1 (en) * | 2000-05-09 | 2001-11-15 | Paieon Inc. | System and method for three-dimensional reconstruction of an artery |
US20050002986A1 (en) * | 2000-05-12 | 2005-01-06 | Robert Falotico | Drug/drug delivery systems for the prevention and treatment of vascular disease |
US20040243097A1 (en) * | 2000-05-12 | 2004-12-02 | Robert Falotico | Antiproliferative drug and delivery device |
US6776796B2 (en) | 2000-05-12 | 2004-08-17 | Cordis Corportation | Antiinflammatory drug and delivery device |
US8236048B2 (en) * | 2000-05-12 | 2012-08-07 | Cordis Corporation | Drug/drug delivery systems for the prevention and treatment of vascular disease |
US6652579B1 (en) | 2000-06-22 | 2003-11-25 | Advanced Cardiovascular Systems, Inc. | Radiopaque stent |
EP1401358B1 (en) * | 2000-06-30 | 2016-08-17 | Medtronic, Inc. | Apparatus for performing a procedure on a cardiac valve |
AU2001273088A1 (en) * | 2000-06-30 | 2002-01-30 | Viacor Incorporated | Intravascular filter with debris entrapment mechanism |
US6540775B1 (en) * | 2000-06-30 | 2003-04-01 | Cordis Corporation | Ultraflexible open cell stent |
US6808533B1 (en) | 2000-07-28 | 2004-10-26 | Atrium Medical Corporation | Covered stent and method of covering a stent |
CN1447669A (en) | 2000-08-18 | 2003-10-08 | 阿特里泰克公司 | Expandable implant devices for filtering blood flow from atrial appendages |
WO2002015824A2 (en) | 2000-08-25 | 2002-02-28 | Kensey Nash Corporation | Covered stents, systems for deploying covered stents |
US6669722B2 (en) | 2000-09-22 | 2003-12-30 | Cordis Corporation | Stent with optimal strength and radiopacity characteristics |
US7766956B2 (en) * | 2000-09-22 | 2010-08-03 | Boston Scientific Scimed, Inc. | Intravascular stent and assembly |
WO2002024247A1 (en) | 2000-09-22 | 2002-03-28 | Kensey Nash Corporation | Drug delivering prostheses and methods of use |
US6652574B1 (en) | 2000-09-28 | 2003-11-25 | Vascular Concepts Holdings Limited | Product and process for manufacturing a wire stent coated with a biocompatible fluoropolymer |
US20020111590A1 (en) * | 2000-09-29 | 2002-08-15 | Davila Luis A. | Medical devices, drug coatings and methods for maintaining the drug coatings thereon |
US7261735B2 (en) * | 2001-05-07 | 2007-08-28 | Cordis Corporation | Local drug delivery devices and methods for maintaining the drug coatings thereon |
JP5100951B2 (en) * | 2000-09-29 | 2012-12-19 | コーディス・コーポレイション | Coated medical device |
US20020051730A1 (en) * | 2000-09-29 | 2002-05-02 | Stanko Bodnar | Coated medical devices and sterilization thereof |
US7037330B1 (en) * | 2000-10-16 | 2006-05-02 | Scimed Life Systems, Inc. | Neurovascular stent and method |
US6783793B1 (en) * | 2000-10-26 | 2004-08-31 | Advanced Cardiovascular Systems, Inc. | Selective coating of medical devices |
US7314483B2 (en) * | 2000-11-16 | 2008-01-01 | Cordis Corp. | Stent graft with branch leg |
US6945991B1 (en) | 2000-11-28 | 2005-09-20 | Boston Scientific/Scimed Life Systems, Inc. | Composite tubular prostheses |
US6790227B2 (en) * | 2001-03-01 | 2004-09-14 | Cordis Corporation | Flexible stent |
US6679911B2 (en) | 2001-03-01 | 2004-01-20 | Cordis Corporation | Flexible stent |
US6942689B2 (en) * | 2001-03-01 | 2005-09-13 | Cordis Corporation | Flexible stent |
AU784552B2 (en) * | 2001-03-02 | 2006-05-04 | Cardinal Health 529, Llc | Flexible stent |
US6660034B1 (en) * | 2001-04-30 | 2003-12-09 | Advanced Cardiovascular Systems, Inc. | Stent for increasing blood flow to ischemic tissues and a method of using the same |
US8182527B2 (en) * | 2001-05-07 | 2012-05-22 | Cordis Corporation | Heparin barrier coating for controlled drug release |
US7560006B2 (en) * | 2001-06-11 | 2009-07-14 | Boston Scientific Scimed, Inc. | Pressure lamination method for forming composite ePTFE/textile and ePTFE/stent/textile prostheses |
CA2450160C (en) * | 2001-06-11 | 2011-03-22 | Boston Scientific Limited | Composite eptfe/textile prosthesis |
US7828833B2 (en) | 2001-06-11 | 2010-11-09 | Boston Scientific Scimed, Inc. | Composite ePTFE/textile prosthesis |
US7201940B1 (en) * | 2001-06-12 | 2007-04-10 | Advanced Cardiovascular Systems, Inc. | Method and apparatus for thermal spray processing of medical devices |
US6565659B1 (en) * | 2001-06-28 | 2003-05-20 | Advanced Cardiovascular Systems, Inc. | Stent mounting assembly and a method of using the same to coat a stent |
US7544206B2 (en) * | 2001-06-29 | 2009-06-09 | Medtronic, Inc. | Method and apparatus for resecting and replacing an aortic valve |
US8771302B2 (en) * | 2001-06-29 | 2014-07-08 | Medtronic, Inc. | Method and apparatus for resecting and replacing an aortic valve |
US8623077B2 (en) | 2001-06-29 | 2014-01-07 | Medtronic, Inc. | Apparatus for replacing a cardiac valve |
FR2826863B1 (en) * | 2001-07-04 | 2003-09-26 | Jacques Seguin | ASSEMBLY FOR PLACING A PROSTHETIC VALVE IN A BODY CONDUIT |
US8252040B2 (en) | 2001-07-20 | 2012-08-28 | Microvention, Inc. | Aneurysm treatment device and method of use |
US8715312B2 (en) | 2001-07-20 | 2014-05-06 | Microvention, Inc. | Aneurysm treatment device and method of use |
US7572288B2 (en) | 2001-07-20 | 2009-08-11 | Microvention, Inc. | Aneurysm treatment device and method of use |
FR2828091B1 (en) | 2001-07-31 | 2003-11-21 | Seguin Jacques | ASSEMBLY ALLOWING THE PLACEMENT OF A PROTHETIC VALVE IN A BODY DUCT |
US20040137066A1 (en) * | 2001-11-26 | 2004-07-15 | Swaminathan Jayaraman | Rationally designed therapeutic intravascular implant coating |
US7097659B2 (en) * | 2001-09-07 | 2006-08-29 | Medtronic, Inc. | Fixation band for affixing a prosthetic heart valve to tissue |
US7252679B2 (en) * | 2001-09-13 | 2007-08-07 | Cordis Corporation | Stent with angulated struts |
US7989018B2 (en) * | 2001-09-17 | 2011-08-02 | Advanced Cardiovascular Systems, Inc. | Fluid treatment of a polymeric coating on an implantable medical device |
US7285304B1 (en) | 2003-06-25 | 2007-10-23 | Advanced Cardiovascular Systems, Inc. | Fluid treatment of a polymeric coating on an implantable medical device |
US6863683B2 (en) | 2001-09-19 | 2005-03-08 | Abbott Laboratoris Vascular Entities Limited | Cold-molding process for loading a stent onto a stent delivery system |
US7195640B2 (en) * | 2001-09-25 | 2007-03-27 | Cordis Corporation | Coated medical devices for the treatment of vulnerable plaque |
US20030065345A1 (en) * | 2001-09-28 | 2003-04-03 | Kevin Weadock | Anastomosis devices and methods for treating anastomotic sites |
US7108701B2 (en) * | 2001-09-28 | 2006-09-19 | Ethicon, Inc. | Drug releasing anastomosis devices and methods for treating anastomotic sites |
US7192441B2 (en) * | 2001-10-16 | 2007-03-20 | Scimed Life Systems, Inc. | Aortic artery aneurysm endovascular prosthesis |
US7033389B2 (en) * | 2001-10-16 | 2006-04-25 | Scimed Life Systems, Inc. | Tubular prosthesis for external agent delivery |
US6752826B2 (en) | 2001-12-14 | 2004-06-22 | Thoratec Corporation | Layered stent-graft and methods of making the same |
US7326237B2 (en) * | 2002-01-08 | 2008-02-05 | Cordis Corporation | Supra-renal anchoring prosthesis |
US7029493B2 (en) * | 2002-01-25 | 2006-04-18 | Cordis Corporation | Stent with enhanced crossability |
US20030171801A1 (en) * | 2002-03-06 | 2003-09-11 | Brian Bates | Partially covered intraluminal support device |
US7288111B1 (en) * | 2002-03-26 | 2007-10-30 | Thoratec Corporation | Flexible stent and method of making the same |
US8721713B2 (en) * | 2002-04-23 | 2014-05-13 | Medtronic, Inc. | System for implanting a replacement valve |
US7223283B2 (en) * | 2002-10-09 | 2007-05-29 | Boston Scientific Scimed, Inc. | Stent with improved flexibility |
US20060271168A1 (en) * | 2002-10-30 | 2006-11-30 | Klaus Kleine | Degradable medical device |
WO2004043507A1 (en) * | 2002-11-07 | 2004-05-27 | Carbon Medical Technologies, Inc. | Biocompatible medical device coatings |
US7144422B1 (en) | 2002-11-13 | 2006-12-05 | Advanced Cardiovascular Systems, Inc. | Drug-eluting stent and methods of making the same |
US7435255B1 (en) | 2002-11-13 | 2008-10-14 | Advnaced Cardiovascular Systems, Inc. | Drug-eluting stent and methods of making |
US7758881B2 (en) * | 2004-06-30 | 2010-07-20 | Advanced Cardiovascular Systems, Inc. | Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device |
US8435550B2 (en) | 2002-12-16 | 2013-05-07 | Abbot Cardiovascular Systems Inc. | Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device |
US7105018B1 (en) * | 2002-12-30 | 2006-09-12 | Advanced Cardiovascular Systems, Inc. | Drug-eluting stent cover and method of use |
CA2514239C (en) * | 2003-01-28 | 2012-03-20 | Gambro Lundia Ab | An apparatus and method for monitoring a vascular access of a patient |
US7393339B2 (en) * | 2003-02-21 | 2008-07-01 | C. R. Bard, Inc. | Multi-lumen catheter with separate distal tips |
US20040181186A1 (en) * | 2003-03-13 | 2004-09-16 | Scimed Life Systems, Inc. | Medical device |
US7186789B2 (en) | 2003-06-11 | 2007-03-06 | Advanced Cardiovascular Systems, Inc. | Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings |
US20050209674A1 (en) * | 2003-09-05 | 2005-09-22 | Kutscher Tuvia D | Balloon assembly (V) |
US20050060020A1 (en) * | 2003-09-17 | 2005-03-17 | Scimed Life Systems, Inc. | Covered stent with biologically active material |
US7198675B2 (en) * | 2003-09-30 | 2007-04-03 | Advanced Cardiovascular Systems | Stent mandrel fixture and method for selectively coating surfaces of a stent |
US7186265B2 (en) * | 2003-12-10 | 2007-03-06 | Medtronic, Inc. | Prosthetic cardiac valves and systems and methods for implanting thereof |
US11278398B2 (en) | 2003-12-23 | 2022-03-22 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US8840663B2 (en) | 2003-12-23 | 2014-09-23 | Sadra Medical, Inc. | Repositionable heart valve method |
US7959666B2 (en) | 2003-12-23 | 2011-06-14 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US8828078B2 (en) | 2003-12-23 | 2014-09-09 | Sadra Medical, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US9526609B2 (en) | 2003-12-23 | 2016-12-27 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8579962B2 (en) | 2003-12-23 | 2013-11-12 | Sadra Medical, Inc. | Methods and apparatus for performing valvuloplasty |
US20120041550A1 (en) | 2003-12-23 | 2012-02-16 | Sadra Medical, Inc. | Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements |
US8343213B2 (en) | 2003-12-23 | 2013-01-01 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US8182528B2 (en) * | 2003-12-23 | 2012-05-22 | Sadra Medical, Inc. | Locking heart valve anchor |
US20050137686A1 (en) * | 2003-12-23 | 2005-06-23 | Sadra Medical, A Delaware Corporation | Externally expandable heart valve anchor and method |
US8287584B2 (en) * | 2005-11-14 | 2012-10-16 | Sadra Medical, Inc. | Medical implant deployment tool |
US8603160B2 (en) * | 2003-12-23 | 2013-12-10 | Sadra Medical, Inc. | Method of using a retrievable heart valve anchor with a sheath |
US7824443B2 (en) | 2003-12-23 | 2010-11-02 | Sadra Medical, Inc. | Medical implant delivery and deployment tool |
US20050137694A1 (en) | 2003-12-23 | 2005-06-23 | Haug Ulrich R. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8951299B2 (en) | 2003-12-23 | 2015-02-10 | Sadra Medical, Inc. | Medical devices and delivery systems for delivering medical devices |
US7780725B2 (en) | 2004-06-16 | 2010-08-24 | Sadra Medical, Inc. | Everting heart valve |
US7445631B2 (en) * | 2003-12-23 | 2008-11-04 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US9005273B2 (en) * | 2003-12-23 | 2015-04-14 | Sadra Medical, Inc. | Assessing the location and performance of replacement heart valves |
EP2529699B1 (en) * | 2003-12-23 | 2014-01-29 | Sadra Medical, Inc. | Repositionable heart valve |
US7381219B2 (en) | 2003-12-23 | 2008-06-03 | Sadra Medical, Inc. | Low profile heart valve and delivery system |
US7329279B2 (en) * | 2003-12-23 | 2008-02-12 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US20050137691A1 (en) * | 2003-12-23 | 2005-06-23 | Sadra Medical | Two piece heart valve and anchor |
US7748389B2 (en) * | 2003-12-23 | 2010-07-06 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US20050137696A1 (en) * | 2003-12-23 | 2005-06-23 | Sadra Medical | Apparatus and methods for protecting against embolization during endovascular heart valve replacement |
US7824442B2 (en) | 2003-12-23 | 2010-11-02 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US9408592B2 (en) | 2003-12-23 | 2016-08-09 | Senorx, Inc. | Biopsy device with aperture orientation and improved tip |
US20050137687A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Heart valve anchor and method |
US8042485B1 (en) * | 2003-12-30 | 2011-10-25 | Advanced Cardiovascular Systems, Inc. | Stent mandrel fixture and method for coating stents |
ITTO20040135A1 (en) | 2004-03-03 | 2004-06-03 | Sorin Biomedica Cardio Spa | CARDIAC VALVE PROSTHESIS |
US20050214339A1 (en) * | 2004-03-29 | 2005-09-29 | Yiwen Tang | Biologically degradable compositions for medical applications |
EP1737391A2 (en) * | 2004-04-13 | 2007-01-03 | Cook Incorporated | Implantable frame with variable compliance |
US20050288481A1 (en) * | 2004-04-30 | 2005-12-29 | Desnoyer Jessica R | Design of poly(ester amides) for the control of agent-release from polymeric compositions |
US8568469B1 (en) | 2004-06-28 | 2013-10-29 | Advanced Cardiovascular Systems, Inc. | Stent locking element and a method of securing a stent on a delivery system |
US8241554B1 (en) | 2004-06-29 | 2012-08-14 | Advanced Cardiovascular Systems, Inc. | Method of forming a stent pattern on a tube |
US7971333B2 (en) * | 2006-05-30 | 2011-07-05 | Advanced Cardiovascular Systems, Inc. | Manufacturing process for polymetric stents |
US8747879B2 (en) * | 2006-04-28 | 2014-06-10 | Advanced Cardiovascular Systems, Inc. | Method of fabricating an implantable medical device to reduce chance of late inflammatory response |
US8747878B2 (en) | 2006-04-28 | 2014-06-10 | Advanced Cardiovascular Systems, Inc. | Method of fabricating an implantable medical device by controlling crystalline structure |
US8778256B1 (en) | 2004-09-30 | 2014-07-15 | Advanced Cardiovascular Systems, Inc. | Deformation of a polymer tube in the fabrication of a medical article |
US7731890B2 (en) * | 2006-06-15 | 2010-06-08 | Advanced Cardiovascular Systems, Inc. | Methods of fabricating stents with enhanced fracture toughness |
US20060020330A1 (en) * | 2004-07-26 | 2006-01-26 | Bin Huang | Method of fabricating an implantable medical device with biaxially oriented polymers |
US20060041102A1 (en) * | 2004-08-23 | 2006-02-23 | Advanced Cardiovascular Systems, Inc. | Implantable devices comprising biologically absorbable polymers having constant rate of degradation and methods for fabricating the same |
US9283099B2 (en) * | 2004-08-25 | 2016-03-15 | Advanced Cardiovascular Systems, Inc. | Stent-catheter assembly with a releasable connection for stent retention |
US20060052867A1 (en) | 2004-09-07 | 2006-03-09 | Medtronic, Inc | Replacement prosthetic heart valve, system and method of implant |
US7229471B2 (en) * | 2004-09-10 | 2007-06-12 | Advanced Cardiovascular Systems, Inc. | Compositions containing fast-leaching plasticizers for improved performance of medical devices |
US7875233B2 (en) | 2004-09-30 | 2011-01-25 | Advanced Cardiovascular Systems, Inc. | Method of fabricating a biaxially oriented implantable medical device |
US8043553B1 (en) | 2004-09-30 | 2011-10-25 | Advanced Cardiovascular Systems, Inc. | Controlled deformation of a polymer tube with a restraining surface in fabricating a medical article |
US8173062B1 (en) | 2004-09-30 | 2012-05-08 | Advanced Cardiovascular Systems, Inc. | Controlled deformation of a polymer tube in fabricating a medical article |
US7905857B2 (en) * | 2005-07-11 | 2011-03-15 | Covidien Ag | Needle assembly including obturator with safety reset |
US7850650B2 (en) * | 2005-07-11 | 2010-12-14 | Covidien Ag | Needle safety shield with reset |
US7828773B2 (en) | 2005-07-11 | 2010-11-09 | Covidien Ag | Safety reset key and needle assembly |
WO2006054107A2 (en) * | 2004-11-19 | 2006-05-26 | Medtronic Inc. | Method and apparatus for treatment of cardiac valves |
US8562672B2 (en) | 2004-11-19 | 2013-10-22 | Medtronic, Inc. | Apparatus for treatment of cardiac valves and method of its manufacture |
US8343071B2 (en) | 2004-12-16 | 2013-01-01 | Senorx, Inc. | Biopsy device with aperture orientation and improved tip |
US20090204021A1 (en) * | 2004-12-16 | 2009-08-13 | Senorx, Inc. | Apparatus and method for accessing a body site |
DE102005003632A1 (en) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Catheter for the transvascular implantation of heart valve prostheses |
US20060178731A1 (en) * | 2005-02-09 | 2006-08-10 | Numed, Inc. | Apparatus for aiding the flow of blood through patient's circulatory system |
ITTO20050074A1 (en) | 2005-02-10 | 2006-08-11 | Sorin Biomedica Cardio Srl | CARDIAC VALVE PROSTHESIS |
US20060216431A1 (en) * | 2005-03-28 | 2006-09-28 | Kerrigan Cameron K | Electrostatic abluminal coating of a stent crimped on a balloon catheter |
US20060224226A1 (en) * | 2005-03-31 | 2006-10-05 | Bin Huang | In-vivo radial orientation of a polymeric implantable medical device |
US20060276882A1 (en) * | 2005-04-11 | 2006-12-07 | Cook Incorporated | Medical device including remodelable material attached to frame |
US7381048B2 (en) * | 2005-04-12 | 2008-06-03 | Advanced Cardiovascular Systems, Inc. | Stents with profiles for gripping a balloon catheter and molds for fabricating stents |
US7962208B2 (en) | 2005-04-25 | 2011-06-14 | Cardiac Pacemakers, Inc. | Method and apparatus for pacing during revascularization |
US7914569B2 (en) | 2005-05-13 | 2011-03-29 | Medtronics Corevalve Llc | Heart valve prosthesis and methods of manufacture and use |
US7291166B2 (en) * | 2005-05-18 | 2007-11-06 | Advanced Cardiovascular Systems, Inc. | Polymeric stent patterns |
US20060276747A1 (en) | 2005-06-06 | 2006-12-07 | Sherwood Services Ag | Needle assembly with removable depth stop |
US7622070B2 (en) * | 2005-06-20 | 2009-11-24 | Advanced Cardiovascular Systems, Inc. | Method of manufacturing an implantable polymeric medical device |
US20060292690A1 (en) * | 2005-06-22 | 2006-12-28 | Cesco Bioengineering Co., Ltd. | Method of making cell growth surface |
US7731692B2 (en) * | 2005-07-11 | 2010-06-08 | Covidien Ag | Device for shielding a sharp tip of a cannula and method of using the same |
US7658880B2 (en) * | 2005-07-29 | 2010-02-09 | Advanced Cardiovascular Systems, Inc. | Polymeric stent polishing method and apparatus |
US7297758B2 (en) * | 2005-08-02 | 2007-11-20 | Advanced Cardiovascular Systems, Inc. | Method for extending shelf-life of constructs of semi-crystallizable polymers |
US20070038290A1 (en) * | 2005-08-15 | 2007-02-15 | Bin Huang | Fiber reinforced composite stents |
US7476245B2 (en) | 2005-08-16 | 2009-01-13 | Advanced Cardiovascular Systems, Inc. | Polymeric stent patterns |
US20070045255A1 (en) * | 2005-08-23 | 2007-03-01 | Klaus Kleine | Laser induced plasma machining with an optimized process gas |
US9248034B2 (en) * | 2005-08-23 | 2016-02-02 | Advanced Cardiovascular Systems, Inc. | Controlled disintegrating implantable medical devices |
US20070045252A1 (en) * | 2005-08-23 | 2007-03-01 | Klaus Kleine | Laser induced plasma machining with a process gas |
US7712606B2 (en) | 2005-09-13 | 2010-05-11 | Sadra Medical, Inc. | Two-part package for medical implant |
US20070078510A1 (en) | 2005-09-26 | 2007-04-05 | Ryan Timothy R | Prosthetic cardiac and venous valves |
US7654735B2 (en) | 2005-11-03 | 2010-02-02 | Covidien Ag | Electronic thermometer |
US7867547B2 (en) | 2005-12-19 | 2011-01-11 | Advanced Cardiovascular Systems, Inc. | Selectively coating luminal surfaces of stents |
US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US20070148251A1 (en) * | 2005-12-22 | 2007-06-28 | Hossainy Syed F A | Nanoparticle releasing medical devices |
US20070151961A1 (en) * | 2006-01-03 | 2007-07-05 | Klaus Kleine | Fabrication of an implantable medical device with a modified laser beam |
US20070156230A1 (en) * | 2006-01-04 | 2007-07-05 | Dugan Stephen R | Stents with radiopaque markers |
US7951185B1 (en) | 2006-01-06 | 2011-05-31 | Advanced Cardiovascular Systems, Inc. | Delivery of a stent at an elevated temperature |
US9078781B2 (en) * | 2006-01-11 | 2015-07-14 | Medtronic, Inc. | Sterile cover for compressible stents used in percutaneous device delivery systems |
US20070179219A1 (en) * | 2006-01-31 | 2007-08-02 | Bin Huang | Method of fabricating an implantable medical device using gel extrusion and charge induced orientation |
EP1988851A2 (en) | 2006-02-14 | 2008-11-12 | Sadra Medical, Inc. | Systems and methods for delivering a medical implant |
US8075615B2 (en) | 2006-03-28 | 2011-12-13 | Medtronic, Inc. | Prosthetic cardiac valve formed from pericardium material and methods of making same |
US7964210B2 (en) * | 2006-03-31 | 2011-06-21 | Abbott Cardiovascular Systems Inc. | Degradable polymeric implantable medical devices with a continuous phase and discrete phase |
US7625403B2 (en) | 2006-04-04 | 2009-12-01 | Medtronic Vascular, Inc. | Valved conduit designed for subsequent catheter delivered valve therapy |
US7740655B2 (en) * | 2006-04-06 | 2010-06-22 | Medtronic Vascular, Inc. | Reinforced surgical conduit for implantation of a stented valve therein |
US7591848B2 (en) | 2006-04-06 | 2009-09-22 | Medtronic Vascular, Inc. | Riveted stent valve for percutaneous use |
US7524331B2 (en) | 2006-04-06 | 2009-04-28 | Medtronic Vascular, Inc. | Catheter delivered valve having a barrier to provide an enhanced seal |
US20070239269A1 (en) * | 2006-04-07 | 2007-10-11 | Medtronic Vascular, Inc. | Stented Valve Having Dull Struts |
US20070239271A1 (en) * | 2006-04-10 | 2007-10-11 | Than Nguyen | Systems and methods for loading a prosthesis onto a minimally invasive delivery system |
US20070244544A1 (en) * | 2006-04-14 | 2007-10-18 | Medtronic Vascular, Inc. | Seal for Enhanced Stented Valve Fixation |
US20070244545A1 (en) * | 2006-04-14 | 2007-10-18 | Medtronic Vascular, Inc. | Prosthetic Conduit With Radiopaque Symmetry Indicators |
US20070244546A1 (en) * | 2006-04-18 | 2007-10-18 | Medtronic Vascular, Inc. | Stent Foundation for Placement of a Stented Valve |
US20070254012A1 (en) * | 2006-04-28 | 2007-11-01 | Ludwig Florian N | Controlled degradation and drug release in stents |
US8069814B2 (en) | 2006-05-04 | 2011-12-06 | Advanced Cardiovascular Systems, Inc. | Stent support devices |
US7761968B2 (en) * | 2006-05-25 | 2010-07-27 | Advanced Cardiovascular Systems, Inc. | Method of crimping a polymeric stent |
US7951194B2 (en) | 2006-05-26 | 2011-05-31 | Abbott Cardiovascular Sysetms Inc. | Bioabsorbable stent with radiopaque coating |
US8752268B2 (en) | 2006-05-26 | 2014-06-17 | Abbott Cardiovascular Systems Inc. | Method of making stents with radiopaque markers |
US8343530B2 (en) * | 2006-05-30 | 2013-01-01 | Abbott Cardiovascular Systems Inc. | Polymer-and polymer blend-bioceramic composite implantable medical devices |
US7842737B2 (en) | 2006-09-29 | 2010-11-30 | Abbott Cardiovascular Systems Inc. | Polymer blend-bioceramic composite implantable medical devices |
US7959940B2 (en) * | 2006-05-30 | 2011-06-14 | Advanced Cardiovascular Systems, Inc. | Polymer-bioceramic composite implantable medical devices |
US20070282434A1 (en) * | 2006-05-30 | 2007-12-06 | Yunbing Wang | Copolymer-bioceramic composite implantable medical devices |
US20080058916A1 (en) * | 2006-05-31 | 2008-03-06 | Bin Huang | Method of fabricating polymeric self-expandable stent |
US8486135B2 (en) | 2006-06-01 | 2013-07-16 | Abbott Cardiovascular Systems Inc. | Implantable medical devices fabricated from branched polymers |
US8034287B2 (en) * | 2006-06-01 | 2011-10-11 | Abbott Cardiovascular Systems Inc. | Radiation sterilization of medical devices |
US20070281073A1 (en) * | 2006-06-01 | 2007-12-06 | Gale David C | Enhanced adhesion of drug delivery coatings on stents |
US20070282433A1 (en) * | 2006-06-01 | 2007-12-06 | Limon Timothy A | Stent with retention protrusions formed during crimping |
US20080124372A1 (en) * | 2006-06-06 | 2008-05-29 | Hossainy Syed F A | Morphology profiles for control of agent release rates from polymer matrices |
US20070286941A1 (en) * | 2006-06-13 | 2007-12-13 | Bin Huang | Surface treatment of a polymeric stent |
US8603530B2 (en) * | 2006-06-14 | 2013-12-10 | Abbott Cardiovascular Systems Inc. | Nanoshell therapy |
US8048448B2 (en) | 2006-06-15 | 2011-11-01 | Abbott Cardiovascular Systems Inc. | Nanoshells for drug delivery |
US8535372B1 (en) | 2006-06-16 | 2013-09-17 | Abbott Cardiovascular Systems Inc. | Bioabsorbable stent with prohealing layer |
US20070290412A1 (en) * | 2006-06-19 | 2007-12-20 | John Capek | Fabricating a stent with selected properties in the radial and axial directions |
US8333000B2 (en) | 2006-06-19 | 2012-12-18 | Advanced Cardiovascular Systems, Inc. | Methods for improving stent retention on a balloon catheter |
US8017237B2 (en) * | 2006-06-23 | 2011-09-13 | Abbott Cardiovascular Systems, Inc. | Nanoshells on polymers |
US9072820B2 (en) * | 2006-06-26 | 2015-07-07 | Advanced Cardiovascular Systems, Inc. | Polymer composite stent with polymer particles |
US20070299511A1 (en) * | 2006-06-27 | 2007-12-27 | Gale David C | Thin stent coating |
US8128688B2 (en) * | 2006-06-27 | 2012-03-06 | Abbott Cardiovascular Systems Inc. | Carbon coating on an implantable device |
US7794776B1 (en) | 2006-06-29 | 2010-09-14 | Abbott Cardiovascular Systems Inc. | Modification of polymer stents with radiation |
US7740791B2 (en) * | 2006-06-30 | 2010-06-22 | Advanced Cardiovascular Systems, Inc. | Method of fabricating a stent with features by blow molding |
US20080009938A1 (en) * | 2006-07-07 | 2008-01-10 | Bin Huang | Stent with a radiopaque marker and method for making the same |
US7823263B2 (en) | 2006-07-11 | 2010-11-02 | Abbott Cardiovascular Systems Inc. | Method of removing stent islands from a stent |
US20080014244A1 (en) * | 2006-07-13 | 2008-01-17 | Gale David C | Implantable medical devices and coatings therefor comprising physically crosslinked block copolymers |
US7998404B2 (en) * | 2006-07-13 | 2011-08-16 | Advanced Cardiovascular Systems, Inc. | Reduced temperature sterilization of stents |
US7757543B2 (en) | 2006-07-13 | 2010-07-20 | Advanced Cardiovascular Systems, Inc. | Radio frequency identification monitoring of stents |
US7794495B2 (en) * | 2006-07-17 | 2010-09-14 | Advanced Cardiovascular Systems, Inc. | Controlled degradation of stents |
US7886419B2 (en) * | 2006-07-18 | 2011-02-15 | Advanced Cardiovascular Systems, Inc. | Stent crimping apparatus and method |
US20080091262A1 (en) * | 2006-10-17 | 2008-04-17 | Gale David C | Drug delivery after biodegradation of the stent scaffolding |
US8016879B2 (en) * | 2006-08-01 | 2011-09-13 | Abbott Cardiovascular Systems Inc. | Drug delivery after biodegradation of the stent scaffolding |
US9173733B1 (en) | 2006-08-21 | 2015-11-03 | Abbott Cardiovascular Systems Inc. | Tracheobronchial implantable medical device and methods of use |
US7988720B2 (en) | 2006-09-12 | 2011-08-02 | Boston Scientific Scimed, Inc. | Longitudinally flexible expandable stent |
US7923022B2 (en) * | 2006-09-13 | 2011-04-12 | Advanced Cardiovascular Systems, Inc. | Degradable polymeric implantable medical devices with continuous phase and discrete phase |
US8834564B2 (en) | 2006-09-19 | 2014-09-16 | Medtronic, Inc. | Sinus-engaging valve fixation member |
US8348996B2 (en) | 2006-09-19 | 2013-01-08 | Medtronic Ventor Technologies Ltd. | Valve prosthesis implantation techniques |
US11304800B2 (en) | 2006-09-19 | 2022-04-19 | Medtronic Ventor Technologies Ltd. | Sinus-engaging valve fixation member |
KR20130095317A (en) | 2006-10-22 | 2013-08-27 | 이데브 테크놀로지스, 아이엔씨. | Devices and methods for stent advancement |
EP3150177B1 (en) | 2006-10-22 | 2021-06-02 | Idev Technologies, Inc. | Methods for securing strand ends and the resulting devices |
US8099849B2 (en) | 2006-12-13 | 2012-01-24 | Abbott Cardiovascular Systems Inc. | Optimizing fracture toughness of polymeric stent |
CA2677633C (en) * | 2007-02-15 | 2015-09-08 | Medtronic, Inc. | Multi-layered stents and methods of implanting |
EP2129333B1 (en) * | 2007-02-16 | 2019-04-03 | Medtronic, Inc | Replacement prosthetic heart valves |
US20080243228A1 (en) * | 2007-03-28 | 2008-10-02 | Yunbing Wang | Implantable medical devices fabricated from block copolymers |
US8262723B2 (en) | 2007-04-09 | 2012-09-11 | Abbott Cardiovascular Systems Inc. | Implantable medical devices fabricated from polymer blends with star-block copolymers |
US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
FR2915087B1 (en) | 2007-04-20 | 2021-11-26 | Corevalve Inc | IMPLANT FOR TREATMENT OF A HEART VALVE, IN PARTICULAR OF A MITRAL VALVE, EQUIPMENT INCLUDING THIS IMPLANT AND MATERIAL FOR PLACING THIS IMPLANT. |
US7829008B2 (en) * | 2007-05-30 | 2010-11-09 | Abbott Cardiovascular Systems Inc. | Fabricating a stent from a blow molded tube |
US7959857B2 (en) * | 2007-06-01 | 2011-06-14 | Abbott Cardiovascular Systems Inc. | Radiation sterilization of medical devices |
US8293260B2 (en) * | 2007-06-05 | 2012-10-23 | Abbott Cardiovascular Systems Inc. | Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices |
US8202528B2 (en) * | 2007-06-05 | 2012-06-19 | Abbott Cardiovascular Systems Inc. | Implantable medical devices with elastomeric block copolymer coatings |
US20080306582A1 (en) * | 2007-06-05 | 2008-12-11 | Yunbing Wang | Implantable medical devices with elastomeric copolymer coatings |
US8425591B1 (en) | 2007-06-11 | 2013-04-23 | Abbott Cardiovascular Systems Inc. | Methods of forming polymer-bioceramic composite medical devices with bioceramic particles |
US8048441B2 (en) | 2007-06-25 | 2011-11-01 | Abbott Cardiovascular Systems, Inc. | Nanobead releasing medical devices |
EP2162101B1 (en) * | 2007-06-25 | 2019-02-20 | MicroVention, Inc. | Self-expanding prosthesis |
US7901452B2 (en) * | 2007-06-27 | 2011-03-08 | Abbott Cardiovascular Systems Inc. | Method to fabricate a stent having selected morphology to reduce restenosis |
US7955381B1 (en) | 2007-06-29 | 2011-06-07 | Advanced Cardiovascular Systems, Inc. | Polymer-bioceramic composite implantable medical device with different types of bioceramic particles |
US8747458B2 (en) | 2007-08-20 | 2014-06-10 | Medtronic Ventor Technologies Ltd. | Stent loading tool and method for use thereof |
US8100855B2 (en) * | 2007-09-17 | 2012-01-24 | Abbott Cardiovascular Systems, Inc. | Methods and devices for eluting agents to a vessel |
US8226701B2 (en) | 2007-09-26 | 2012-07-24 | Trivascular, Inc. | Stent and delivery system for deployment thereof |
US20090082845A1 (en) * | 2007-09-26 | 2009-03-26 | Boston Scientific Corporation | Alignment stent apparatus and method |
US8066755B2 (en) * | 2007-09-26 | 2011-11-29 | Trivascular, Inc. | System and method of pivoted stent deployment |
US8663309B2 (en) * | 2007-09-26 | 2014-03-04 | Trivascular, Inc. | Asymmetric stent apparatus and method |
US20090082841A1 (en) * | 2007-09-26 | 2009-03-26 | Boston Scientific Corporation | Apparatus for securing stent barbs |
CN101917929A (en) | 2007-10-04 | 2010-12-15 | 特里瓦斯库拉尔公司 | Modular vascular graft for low profile percutaneous delivery |
US20090138079A1 (en) * | 2007-10-10 | 2009-05-28 | Vector Technologies Ltd. | Prosthetic heart valve for transfemoral delivery |
US9848981B2 (en) | 2007-10-12 | 2017-12-26 | Mayo Foundation For Medical Education And Research | Expandable valve prosthesis with sealing mechanism |
US8357104B2 (en) | 2007-11-01 | 2013-01-22 | Coviden Lp | Active stylet safety shield |
US8328861B2 (en) | 2007-11-16 | 2012-12-11 | Trivascular, Inc. | Delivery system and method for bifurcated graft |
US8083789B2 (en) * | 2007-11-16 | 2011-12-27 | Trivascular, Inc. | Securement assembly and method for expandable endovascular device |
US20100331958A1 (en) * | 2007-12-20 | 2010-12-30 | Trivascular, Inc. | Hinged endovascular device |
EP2254513B1 (en) * | 2008-01-24 | 2015-10-28 | Medtronic, Inc. | Stents for prosthetic heart valves |
US8157853B2 (en) | 2008-01-24 | 2012-04-17 | Medtronic, Inc. | Delivery systems and methods of implantation for prosthetic heart valves |
US9149358B2 (en) * | 2008-01-24 | 2015-10-06 | Medtronic, Inc. | Delivery systems for prosthetic heart valves |
US20090287290A1 (en) * | 2008-01-24 | 2009-11-19 | Medtronic, Inc. | Delivery Systems and Methods of Implantation for Prosthetic Heart Valves |
JP5687070B2 (en) * | 2008-01-24 | 2015-03-18 | メドトロニック,インコーポレイテッド | Stent for prosthetic heart valve |
US9393115B2 (en) | 2008-01-24 | 2016-07-19 | Medtronic, Inc. | Delivery systems and methods of implantation for prosthetic heart valves |
US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
BR112012021347A2 (en) | 2008-02-26 | 2019-09-24 | Jenavalve Tecnology Inc | stent for positioning and anchoring a valve prosthesis at an implantation site in a patient's heart |
US8196279B2 (en) * | 2008-02-27 | 2012-06-12 | C. R. Bard, Inc. | Stent-graft covering process |
US8313525B2 (en) | 2008-03-18 | 2012-11-20 | Medtronic Ventor Technologies, Ltd. | Valve suturing and implantation procedures |
US8430927B2 (en) | 2008-04-08 | 2013-04-30 | Medtronic, Inc. | Multiple orifice implantable heart valve and methods of implantation |
US8312825B2 (en) | 2008-04-23 | 2012-11-20 | Medtronic, Inc. | Methods and apparatuses for assembly of a pericardial prosthetic heart valve |
US8696743B2 (en) * | 2008-04-23 | 2014-04-15 | Medtronic, Inc. | Tissue attachment devices and methods for prosthetic heart valves |
ATE554731T1 (en) | 2008-05-16 | 2012-05-15 | Sorin Biomedica Cardio Srl | ATRAAUMATIC PROSTHETIC HEART VALVE PROSTHESIS |
EP4018967A1 (en) | 2008-09-15 | 2022-06-29 | Medtronic Ventor Technologies Ltd | Prosthetic heart valve having identifiers for aiding in radiographic positioning |
US8721714B2 (en) | 2008-09-17 | 2014-05-13 | Medtronic Corevalve Llc | Delivery system for deployment of medical devices |
US8986361B2 (en) | 2008-10-17 | 2015-03-24 | Medtronic Corevalve, Inc. | Delivery system for deployment of medical devices |
US8834563B2 (en) | 2008-12-23 | 2014-09-16 | Sorin Group Italia S.R.L. | Expandable prosthetic valve having anchoring appendages |
ES2523218T3 (en) * | 2009-04-27 | 2014-11-24 | Sorin Group Italia S.R.L. | Prosthetic vascular duct |
US8808369B2 (en) * | 2009-10-05 | 2014-08-19 | Mayo Foundation For Medical Education And Research | Minimally invasive aortic valve replacement |
US8845682B2 (en) * | 2009-10-13 | 2014-09-30 | E-Pacing, Inc. | Vasculature closure devices and methods |
US8808353B2 (en) | 2010-01-30 | 2014-08-19 | Abbott Cardiovascular Systems Inc. | Crush recoverable polymer scaffolds having a low crossing profile |
US8568471B2 (en) | 2010-01-30 | 2013-10-29 | Abbott Cardiovascular Systems Inc. | Crush recoverable polymer scaffolds |
US20110218609A1 (en) * | 2010-02-10 | 2011-09-08 | Trivascular, Inc. | Fill tube manifold and delivery methods for endovascular graft |
US9226826B2 (en) * | 2010-02-24 | 2016-01-05 | Medtronic, Inc. | Transcatheter valve structure and methods for valve delivery |
US8652204B2 (en) | 2010-04-01 | 2014-02-18 | Medtronic, Inc. | Transcatheter valve with torsion spring fixation and related systems and methods |
DE102010018539A1 (en) * | 2010-04-28 | 2011-11-03 | Acandis Gmbh & Co. Kg | A method of manufacturing a medical device for endoluminal treatments and starting product for the manufacture of a medical device |
IT1400327B1 (en) | 2010-05-21 | 2013-05-24 | Sorin Biomedica Cardio Srl | SUPPORT DEVICE FOR VALVULAR PROSTHESIS AND CORRESPONDING CORRESPONDENT. |
CN103002833B (en) | 2010-05-25 | 2016-05-11 | 耶拿阀门科技公司 | Artificial heart valve and comprise artificial heart valve and support through conduit carry interior prosthese |
US9023095B2 (en) | 2010-05-27 | 2015-05-05 | Idev Technologies, Inc. | Stent delivery system with pusher assembly |
CN106073946B (en) | 2010-09-10 | 2022-01-04 | 西美蒂斯股份公司 | Valve replacement device, delivery device for a valve replacement device and method of producing a valve replacement device |
EP2658484A1 (en) | 2010-12-30 | 2013-11-06 | Boston Scientific Scimed, Inc. | Multi stage opening stent designs |
EP2486893B1 (en) | 2011-02-14 | 2017-07-05 | Sorin Group Italia S.r.l. | Sutureless anchoring device for cardiac valve prostheses |
EP2486894B1 (en) | 2011-02-14 | 2021-06-09 | Sorin Group Italia S.r.l. | Sutureless anchoring device for cardiac valve prostheses |
EP2680797B1 (en) | 2011-03-03 | 2016-10-26 | Boston Scientific Scimed, Inc. | Low strain high strength stent |
US8790388B2 (en) | 2011-03-03 | 2014-07-29 | Boston Scientific Scimed, Inc. | Stent with reduced profile |
EP4119095A1 (en) | 2011-03-21 | 2023-01-18 | Cephea Valve Technologies, Inc. | Disk-based valve apparatus |
US20120259351A1 (en) * | 2011-04-06 | 2012-10-11 | Mark Chak | Method of and an apparatus for restoring blood flow through a blood vessel |
EP2520251A1 (en) | 2011-05-05 | 2012-11-07 | Symetis SA | Method and Apparatus for Compressing Stent-Valves |
JP2014522263A (en) | 2011-05-11 | 2014-09-04 | マイクロベンション インコーポレイテッド | Device for occluding a lumen |
WO2013009975A1 (en) | 2011-07-12 | 2013-01-17 | Boston Scientific Scimed, Inc. | Coupling system for medical devices |
US8726483B2 (en) | 2011-07-29 | 2014-05-20 | Abbott Cardiovascular Systems Inc. | Methods for uniform crimping and deployment of a polymer scaffold |
US9131926B2 (en) | 2011-11-10 | 2015-09-15 | Boston Scientific Scimed, Inc. | Direct connect flush system |
US8940014B2 (en) | 2011-11-15 | 2015-01-27 | Boston Scientific Scimed, Inc. | Bond between components of a medical device |
US8951243B2 (en) | 2011-12-03 | 2015-02-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US9510945B2 (en) | 2011-12-20 | 2016-12-06 | Boston Scientific Scimed Inc. | Medical device handle |
US9277993B2 (en) | 2011-12-20 | 2016-03-08 | Boston Scientific Scimed, Inc. | Medical device delivery systems |
EP2609893B1 (en) | 2011-12-29 | 2014-09-03 | Sorin Group Italia S.r.l. | A kit for implanting prosthetic vascular conduits |
US10172708B2 (en) | 2012-01-25 | 2019-01-08 | Boston Scientific Scimed, Inc. | Valve assembly with a bioabsorbable gasket and a replaceable valve implant |
WO2013120082A1 (en) | 2012-02-10 | 2013-08-15 | Kassab Ghassan S | Methods and uses of biological tissues for various stent and other medical applications |
US8992595B2 (en) | 2012-04-04 | 2015-03-31 | Trivascular, Inc. | Durable stent graft with tapered struts and stable delivery methods and devices |
US9498363B2 (en) | 2012-04-06 | 2016-11-22 | Trivascular, Inc. | Delivery catheter for endovascular device |
US9883941B2 (en) | 2012-06-19 | 2018-02-06 | Boston Scientific Scimed, Inc. | Replacement heart valve |
EP2953580A2 (en) | 2013-02-11 | 2015-12-16 | Cook Medical Technologies LLC | Expandable support frame and medical device |
JP6561044B2 (en) | 2013-05-03 | 2019-08-14 | メドトロニック,インコーポレイテッド | Valve transfer tool |
EP3021762B1 (en) | 2013-07-15 | 2020-03-04 | E-Pacing, Inc. | Vasculature closure devices |
US9561103B2 (en) | 2013-07-17 | 2017-02-07 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
JP6563394B2 (en) | 2013-08-30 | 2019-08-21 | イェーナヴァルヴ テクノロジー インコーポレイテッド | Radially foldable frame for an artificial valve and method for manufacturing the frame |
US9901445B2 (en) | 2014-11-21 | 2018-02-27 | Boston Scientific Scimed, Inc. | Valve locking mechanism |
WO2016093877A1 (en) | 2014-12-09 | 2016-06-16 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US10449043B2 (en) | 2015-01-16 | 2019-10-22 | Boston Scientific Scimed, Inc. | Displacement based lock and release mechanism |
US9861477B2 (en) | 2015-01-26 | 2018-01-09 | Boston Scientific Scimed Inc. | Prosthetic heart valve square leaflet-leaflet stitch |
US9788942B2 (en) | 2015-02-03 | 2017-10-17 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
US10201417B2 (en) | 2015-02-03 | 2019-02-12 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
US9999527B2 (en) | 2015-02-11 | 2018-06-19 | Abbott Cardiovascular Systems Inc. | Scaffolds having radiopaque markers |
US10426617B2 (en) | 2015-03-06 | 2019-10-01 | Boston Scientific Scimed, Inc. | Low profile valve locking mechanism and commissure assembly |
US10285809B2 (en) | 2015-03-06 | 2019-05-14 | Boston Scientific Scimed Inc. | TAVI anchoring assist device |
FR3033494B1 (en) * | 2015-03-10 | 2017-03-24 | Carmat | TISSUE STENT AND METHOD FOR PRODUCING THE SAME |
US10080652B2 (en) | 2015-03-13 | 2018-09-25 | Boston Scientific Scimed, Inc. | Prosthetic heart valve having an improved tubular seal |
JP6767388B2 (en) | 2015-05-01 | 2020-10-14 | イェーナヴァルヴ テクノロジー インコーポレイテッド | Devices and methods to reduce the proportion of pacemakers in heart valve replacement |
EP3294221B1 (en) | 2015-05-14 | 2024-03-06 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
WO2016183523A1 (en) | 2015-05-14 | 2016-11-17 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US9700443B2 (en) | 2015-06-12 | 2017-07-11 | Abbott Cardiovascular Systems Inc. | Methods for attaching a radiopaque marker to a scaffold |
US10195392B2 (en) | 2015-07-02 | 2019-02-05 | Boston Scientific Scimed, Inc. | Clip-on catheter |
US10335277B2 (en) | 2015-07-02 | 2019-07-02 | Boston Scientific Scimed Inc. | Adjustable nosecone |
US10136991B2 (en) | 2015-08-12 | 2018-11-27 | Boston Scientific Scimed Inc. | Replacement heart valve implant |
US10179041B2 (en) | 2015-08-12 | 2019-01-15 | Boston Scientific Scimed Icn. | Pinless release mechanism |
US10779940B2 (en) | 2015-09-03 | 2020-09-22 | Boston Scientific Scimed, Inc. | Medical device handle |
US10342660B2 (en) | 2016-02-02 | 2019-07-09 | Boston Scientific Inc. | Tensioned sheathing aids |
EP4183371A1 (en) | 2016-05-13 | 2023-05-24 | JenaValve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system |
US10583005B2 (en) | 2016-05-13 | 2020-03-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US10245136B2 (en) | 2016-05-13 | 2019-04-02 | Boston Scientific Scimed Inc. | Containment vessel with implant sheathing guide |
US10201416B2 (en) | 2016-05-16 | 2019-02-12 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
US11331187B2 (en) | 2016-06-17 | 2022-05-17 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
CA3051272C (en) | 2017-01-23 | 2023-08-22 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
AU2018203053B2 (en) | 2017-01-23 | 2020-03-05 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
WO2018138658A1 (en) | 2017-01-27 | 2018-08-02 | Jenavalve Technology, Inc. | Heart valve mimicry |
US10828154B2 (en) | 2017-06-08 | 2020-11-10 | Boston Scientific Scimed, Inc. | Heart valve implant commissure support structure |
WO2019028161A1 (en) | 2017-08-01 | 2019-02-07 | Boston Scientific Scimed, Inc. | Medical implant locking mechanism |
US10939996B2 (en) | 2017-08-16 | 2021-03-09 | Boston Scientific Scimed, Inc. | Replacement heart valve commissure assembly |
WO2019144069A2 (en) | 2018-01-19 | 2019-07-25 | Boston Scientific Scimed, Inc. | Inductance mode deployment sensors for transcatheter valve system |
WO2019144071A1 (en) | 2018-01-19 | 2019-07-25 | Boston Scientific Scimed, Inc. | Medical device delivery system with feedback loop |
US11147668B2 (en) | 2018-02-07 | 2021-10-19 | Boston Scientific Scimed, Inc. | Medical device delivery system with alignment feature |
US11439732B2 (en) | 2018-02-26 | 2022-09-13 | Boston Scientific Scimed, Inc. | Embedded radiopaque marker in adaptive seal |
US11229517B2 (en) | 2018-05-15 | 2022-01-25 | Boston Scientific Scimed, Inc. | Replacement heart valve commissure assembly |
WO2019224577A1 (en) | 2018-05-23 | 2019-11-28 | Sorin Group Italia S.R.L. | A cardiac valve prosthesis |
WO2019241477A1 (en) | 2018-06-13 | 2019-12-19 | Boston Scientific Scimed, Inc. | Replacement heart valve delivery device |
US11241312B2 (en) | 2018-12-10 | 2022-02-08 | Boston Scientific Scimed, Inc. | Medical device delivery system including a resistance member |
WO2020210659A1 (en) * | 2019-04-11 | 2020-10-15 | Boston Scientific Scimed, Inc. | Delivery systems for devices with unsupported structure |
US11439504B2 (en) | 2019-05-10 | 2022-09-13 | Boston Scientific Scimed, Inc. | Replacement heart valve with improved cusp washout and reduced loading |
EP3988062A4 (en) * | 2019-06-19 | 2023-04-19 | Hangzhou Endonom Medtech Co., Ltd | Segmental covered stent and preparation method therefor |
US11324583B1 (en) | 2021-07-06 | 2022-05-10 | Archo Medical LTDA | Multi-lumen stent-graft and related surgical methods |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5123917A (en) * | 1990-04-27 | 1992-06-23 | Lee Peter Y | Expandable intraluminal vascular graft |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6028434Y2 (en) * | 1980-06-16 | 1985-08-28 | 建部 容保 | Artificial blood vessel |
US4503569A (en) * | 1983-03-03 | 1985-03-12 | Dotter Charles T | Transluminally placed expandable graft prosthesis |
US4617332A (en) * | 1984-08-31 | 1986-10-14 | University Of Dayton | Phase change compositions |
US4733665C2 (en) * | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
US4793348A (en) * | 1986-11-15 | 1988-12-27 | Palmaz Julio C | Balloon expandable vena cava filter to prevent migration of lower extremity venous clots into the pulmonary circulation |
US4886062A (en) * | 1987-10-19 | 1989-12-12 | Medtronic, Inc. | Intravascular radially expandable stent and method of implant |
US4820298A (en) * | 1987-11-20 | 1989-04-11 | Leveen Eric G | Internal vascular prosthesis |
US4830003A (en) * | 1988-06-17 | 1989-05-16 | Wolff Rodney G | Compressive stent and delivery system |
US4856516A (en) * | 1989-01-09 | 1989-08-15 | Cordis Corporation | Endovascular stent apparatus and method |
US5122154A (en) * | 1990-08-15 | 1992-06-16 | Rhodes Valentine J | Endovascular bypass graft |
US5217483A (en) * | 1990-11-28 | 1993-06-08 | Numed, Inc. | Intravascular radially expandable stent |
US5116365A (en) * | 1991-02-22 | 1992-05-26 | Cordis Corporation | Stent apparatus and method for making |
-
1993
- 1993-10-29 US US08/145,435 patent/US5389106A/en not_active Expired - Lifetime
-
1994
- 1994-10-28 WO PCT/US1994/012429 patent/WO1995011720A1/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5123917A (en) * | 1990-04-27 | 1992-06-23 | Lee Peter Y | Expandable intraluminal vascular graft |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9867727B2 (en) | 1998-02-09 | 2018-01-16 | Trivascular, Inc. | Endovascular graft |
US10548750B2 (en) | 1998-02-09 | 2020-02-04 | Trivascular, Inc. | Endovascular graft |
US8267989B2 (en) | 2004-01-30 | 2012-09-18 | Trivascular, Inc. | Inflatable porous implants and methods for drug delivery |
US11166811B2 (en) | 2018-03-02 | 2021-11-09 | James Yashu Coe | Transcatheter valve |
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US5389106A (en) | 1995-02-14 |
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