WO1995006518A1 - Polymeric surfactant-encapsulated microbubbles and their use in ultrasound imaging - Google Patents
Polymeric surfactant-encapsulated microbubbles and their use in ultrasound imaging Download PDFInfo
- Publication number
- WO1995006518A1 WO1995006518A1 PCT/GB1994/001923 GB9401923W WO9506518A1 WO 1995006518 A1 WO1995006518 A1 WO 1995006518A1 GB 9401923 W GB9401923 W GB 9401923W WO 9506518 A1 WO9506518 A1 WO 9506518A1
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- WO
- WIPO (PCT)
- Prior art keywords
- copolymer surfactant
- contrast agent
- groups
- domains
- copolymer
- Prior art date
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- BDAWXSQJJCIFIK-UHFFFAOYSA-N potassium methoxide Chemical compound [K+].[O-]C BDAWXSQJJCIFIK-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
- C09K23/34—Higher-molecular-weight carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
- C09K23/42—Ethers, e.g. polyglycol ethers of alcohols or phenols
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
- Y10T428/2985—Solid-walled microcapsule from synthetic polymer
Abstract
Description
Claims
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SK260-96A SK26096A3 (en) | 1993-09-03 | 1994-09-05 | Contrasting agent, method of manufacture thereof and application |
AT94925549T ATE216282T1 (en) | 1993-09-03 | 1994-09-05 | MICROBUBBLES ENCAPSULED WITH POLYMERIC SURFACTANTS AND THEIR USE IN ULTRASONIC DIAGNOSTICS |
EE9600025A EE03237B1 (en) | 1993-09-03 | 1994-09-05 | Contrast agent, method for its preparation and use, copolymer surfactant, emulsion containing it and their use |
JP50801995A JP3552721B2 (en) | 1993-09-03 | 1994-09-05 | Microbubbles encapsulated with a polymeric surfactant and their use in ultrasound imaging |
DE69430432T DE69430432T2 (en) | 1993-09-03 | 1994-09-05 | MICROBUBLES, CAPSULE WITH POLYMERS SURFACE, AND THEIR USE IN ULTRASOUND DIAGNOSTICS |
US08/602,797 US5919434A (en) | 1993-09-03 | 1994-09-05 | Polymeric surfactant-encapsulated microbubbles and their use in ultrasound imaging |
NZ271704A NZ271704A (en) | 1993-09-03 | 1994-09-05 | Contrast agent comprising gas bubbles encapsulated by non-polymerisable block or graft copolymer surfactant; polymer surfactants |
EP94925549A EP0717658B1 (en) | 1993-09-03 | 1994-09-05 | Polymeric surfactant-encapsulated microbubbles and their use in ultrasound imaging |
AU75415/94A AU689495B2 (en) | 1993-09-03 | 1994-09-05 | Polymeric surfactant-encapsulated microbubbles and their use in ultrasound im aging |
NO960824A NO960824L (en) | 1993-09-03 | 1996-02-29 | Gaseous Contrasts - USCA 16 |
FI960983A FI960983A0 (en) | 1993-09-03 | 1996-03-01 | With polymeric surfactant nested microbubbles and their use in ultrasound imaging |
US08/610,257 US5990263A (en) | 1994-09-05 | 1996-03-04 | Contrast agents |
BG100467A BG100467A (en) | 1993-09-03 | 1996-03-29 | Polymeric surfactant-encapsulated microbubbles and their use in ultrasound imaging |
LVP-96-94A LV11438B (en) | 1993-09-03 | 1996-04-02 | Polymeric surfactant - encapsulated microbubbles and their use in ultrasound imaging |
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EP0844016A2 (en) * | 1996-11-25 | 1998-05-27 | Nycomed Imaging As | Polyoxyethylene fatty acid ester surfactants and use thereof |
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US9039870B2 (en) | 2006-10-09 | 2015-05-26 | Clariant Finance (Bvi) Limited | Method for producing alkaline (meth)acrylamides |
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EP0717658A1 (en) | 1996-06-26 |
DE69430432T2 (en) | 2002-12-12 |
EE03237B1 (en) | 1999-12-15 |
CZ62796A3 (en) | 1997-03-12 |
CA2170906A1 (en) | 1995-03-09 |
NO960824D0 (en) | 1996-02-29 |
AU689495B2 (en) | 1998-04-02 |
BG100467A (en) | 1996-12-31 |
LV11438B (en) | 1996-12-20 |
ATE216282T1 (en) | 2002-05-15 |
US5919434A (en) | 1999-07-06 |
PL313290A1 (en) | 1996-06-24 |
HU9600515D0 (en) | 1996-04-29 |
GB9318288D0 (en) | 1993-10-20 |
CN1072521C (en) | 2001-10-10 |
SG46373A1 (en) | 1998-01-20 |
LV11438A (en) | 1996-08-20 |
JP3552721B2 (en) | 2004-08-11 |
JPH09503202A (en) | 1997-03-31 |
DE69430432D1 (en) | 2002-05-23 |
AU7541594A (en) | 1995-03-22 |
ES2177582T3 (en) | 2002-12-16 |
FI960983A (en) | 1996-03-01 |
FI960983A0 (en) | 1996-03-01 |
CN1136285A (en) | 1996-11-20 |
SK26096A3 (en) | 1996-08-07 |
EP0717658B1 (en) | 2002-04-17 |
NO960824L (en) | 1996-04-29 |
HUT75289A (en) | 1997-05-28 |
NZ271704A (en) | 1997-12-19 |
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