WO1991015244A3 - Stable microbubbles suspensions injectable into living organisms - Google Patents
Stable microbubbles suspensions injectable into living organisms Download PDFInfo
- Publication number
- WO1991015244A3 WO1991015244A3 PCT/EP1991/000620 EP9100620W WO9115244A3 WO 1991015244 A3 WO1991015244 A3 WO 1991015244A3 EP 9100620 W EP9100620 W EP 9100620W WO 9115244 A3 WO9115244 A3 WO 9115244A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- living organisms
- stable microbubbles
- microbubbles suspensions
- injectable
- suspensions injectable
- Prior art date
Links
- 239000000725 suspension Substances 0.000 title abstract 3
- 239000004094 surface-active agent Substances 0.000 abstract 3
- 239000008346 aqueous phase Substances 0.000 abstract 2
- 239000002872 contrast media Substances 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 239000002502 liposome Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
Abstract
Priority Applications (28)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002056371A CA2056371C (en) | 1990-04-02 | 1991-04-02 | Stable microbubbles suspensions injectable into living organisms |
EP91907163A EP0474833B2 (en) | 1990-04-02 | 1991-04-02 | Stable microbubbles suspensions injectable into living organisms |
KR1019910701733A KR960002184B1 (en) | 1990-04-02 | 1991-04-02 | Microbubble suspensions injectable into living organisms and the |
DE69111719T DE69111719T3 (en) | 1990-04-02 | 1991-04-02 | STABLE MICROBASE SUSPENSIONS FOR INJECTION IN LIVING. |
US08/128,540 US5380519A (en) | 1990-04-02 | 1993-09-29 | Stable microbubbles suspensions injectable into living organisms |
US08/315,347 US5531980A (en) | 1990-04-02 | 1994-09-30 | Stable microbubbles suspensions injectable into living organisms |
US08/457,581 US5567414A (en) | 1990-04-02 | 1995-06-01 | Stable microbubbles suspensions injectable into living organisms |
US08/456,385 US5658551A (en) | 1990-04-02 | 1995-06-01 | Stable microbubbles suspensions injectable into living organisms |
GR950402454T GR3017324T3 (en) | 1990-04-02 | 1995-09-06 | Stable microbubbles suspensions injectable into living organisms. |
US08/853,936 US6110443A (en) | 1990-04-02 | 1997-05-09 | Dry stable formation to produce microbubble suspension for ultrasound |
US08/893,371 US7033574B1 (en) | 1990-04-02 | 1997-07-15 | Stable microbubbles suspensions injectable into living organisms |
US09/115,963 USRE39146E1 (en) | 1990-04-02 | 1998-07-15 | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
US09/401,836 US20010012507A1 (en) | 1990-04-02 | 1999-09-22 | Ultrasound contrast agents and methods of making and using them |
US09/401,835 US20010008626A1 (en) | 1990-04-02 | 1999-09-22 | Ultrasound contrast agents and methods of making and using them |
US09/401,838 US6613306B1 (en) | 1990-04-02 | 1999-09-22 | Ultrasound contrast agents and methods of making and using them |
US09/748,120 US20010024640A1 (en) | 1990-04-02 | 2000-12-27 | Ultrasound contrast agents and methods of making and using them |
US10/061,299 US6881397B2 (en) | 1990-04-02 | 2002-02-04 | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
US10/102,684 US20030064030A1 (en) | 1990-04-02 | 2002-03-22 | Ultrasound contrast agents and methods of making and using them |
US10/120,390 US6989141B2 (en) | 1990-05-18 | 2002-04-12 | Ultrasound contrast agents and methods of making and using them |
US10/226,244 US6896875B2 (en) | 1990-04-02 | 2002-08-23 | Mixable combination for generating a suspension of stable microbubbles for ultrasonic imaging |
US10/336,823 US20030194376A1 (en) | 1990-05-18 | 2003-01-06 | Ultrasound contrast agents and methods of making and using them |
US10/336,760 US20030185759A1 (en) | 1990-05-18 | 2003-01-06 | Ultrasound contrast agents and methods of making and using them |
US10/809,677 US20040208826A1 (en) | 1990-04-02 | 2004-03-26 | Ultrasound contrast agents and methods of making and using them |
US10/962,460 US20050058605A1 (en) | 1990-04-02 | 2004-10-13 | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
US11/085,169 US20050207980A1 (en) | 1990-04-02 | 2005-03-22 | Stable microbubbles suspensions injectable into living organisms |
US11/231,865 US20060034771A1 (en) | 1990-04-02 | 2005-09-22 | Ultrasound contrast agents and methods of making and using them |
US11/444,362 US20060257321A1 (en) | 1990-04-02 | 2006-06-01 | Ultrasound contrast agents and methods of making and using them |
US11/851,769 US20080063603A1 (en) | 1990-04-02 | 2007-09-07 | Ultrasound contrast agents and methods of making and using them |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP90810262.7 | 1990-04-02 | ||
EP90810262 | 1990-04-02 |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US07/775,989 A-371-Of-International US5271928A (en) | 1990-04-02 | 1991-04-02 | Stable microbubbles suspensions injectable into living organisms |
US08/128,540 Division US5380519A (en) | 1990-04-02 | 1993-09-29 | Stable microbubbles suspensions injectable into living organisms |
US08/380,588 Division US5578292A (en) | 1990-04-02 | 1995-01-30 | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1991015244A2 WO1991015244A2 (en) | 1991-10-17 |
WO1991015244A3 true WO1991015244A3 (en) | 1991-11-14 |
Family
ID=8205915
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1991/000620 WO1991015244A2 (en) | 1990-04-02 | 1991-04-02 | Stable microbubbles suspensions injectable into living organisms |
Country Status (19)
Country | Link |
---|---|
US (13) | US5271928A (en) |
EP (1) | EP0474833B2 (en) |
JP (3) | JP2842453B2 (en) |
KR (1) | KR960002184B1 (en) |
CN (1) | CN1055413C (en) |
AT (1) | ATE125711T1 (en) |
AU (1) | AU630030B2 (en) |
CA (1) | CA2056371C (en) |
DE (1) | DE69111719T3 (en) |
DK (1) | DK0474833T4 (en) |
ES (1) | ES2075438T5 (en) |
GR (1) | GR3017324T3 (en) |
IE (1) | IE69018B1 (en) |
IL (1) | IL97730A (en) |
IN (1) | IN172208B (en) |
IS (1) | IS3686A7 (en) |
NZ (1) | NZ237637A (en) |
WO (1) | WO1991015244A2 (en) |
ZA (1) | ZA912427B (en) |
Families Citing this family (340)
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