|Publication number||USRE39539 E1|
|Application number||US 11/097,942|
|Publication date||3 Apr 2007|
|Filing date||1 Apr 2005|
|Priority date||19 Aug 1996|
|Also published as||USRE41376, USRE42471|
|Publication number||097942, 11097942, US RE39539 E1, US RE39539E1, US-E1-RE39539, USRE39539 E1, USRE39539E1|
|Inventors||William C. Torch|
|Original Assignee||Torch William C|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (16), Referenced by (59), Classifications (44), Legal Events (2)|
|External Links: USPTO, USPTO Assignment, Espacenet|
This application is a reissue of application Ser. No. 09/740,738, filed Dec. 18, 2000, U.S. Pat. No. 6,542,081, which is a continuation-in-part of application Ser. No. 09/104,258, filed Jun. 24, 1998, issuing as U.S. Pat. No. 6,163,281 on Dec. 19, 2000, which is a continuation-in-part of application Ser. No. 08/978,100, filed Nov. 25, 1997, now U.S. Pat. No. 6,246,344 issued Jun. 12, 2001, which is a continuation-in-part of application Ser. No. 08/699,670, filed Aug. 19, 1996, now U.S. Pat. No. 5,748,113 issued May 5, 1998, the disclosures of which are expressly incorporated herein by reference.
The present invention relates generally to systems and methods for monitoring movement of a human eye, and more particularly to systems and methods for real-time monitoring of fatigue and other states of mind in individuals, purposeful communication, and/or controlling devices based upon movement of their eye, eyelid, and/or other components of their eye.
There have been attempts to use movement of the human eye to monitor involuntary conditions, specifically a person's wakefulness or drowsiness. For example, U.S. Pat. No. 3,863,243 discloses a device that sounds an alarm to warn a person using the device that they are beginning to fall asleep. The device includes a frame similar to a set of eyeglasses onto which is mounted a fiber optic bundle and a photocell that are directed towards the user's eye when the frame is worn. The fiber optic bundle is coupled to a source of light and a pulse generator to emit light towards the user's eye.
The photocell detects the intensity of light reflected off of the user's eye, i.e., either by the eyelid when the eye is closed or the eye surface when the eye is open. Circuitry receives a signal from the photocell, and uses a timer to distinguish between regular blinks, and an extended time period during which the eye is closed, i.e., a time period that may indicate that the person is falling asleep. When a threshold time elapses, an alarm is sounded to notify and/or wake the user. This device, however, requires running wires and fiber optic bundles from the frame to external components, e.g., the pulse generator and the required circuitry, and for this reason, the device may be awkward or inconvenient to use.
Other devices, such as those disclosed in U.S. Pat. Nos. 5,469,143 and 4,359,724, directly engage the eyelid or eyebrow of a user to detect movement of the eye and activate an alarm when a drowsiness condition is detected. These mechanical devices may be mounted directly onto the skin to detect muscle movement or may involve placing a mechanical arm against the eyelid, and consequently may be uncomfortable to wear and use.
In addition, some devices may detect eye movement, but may not be able to distinguish when the eye is opened or closed. For example, it may be desirable to measure the percentage of total time that the eyelids are closed as a function of time or the area of the palpebral fissure that is covered by the eyelid as the eye is opened or closed, commonly known as “PERCLOS,” for example during medical research or when monitoring driver alertness. Devices that merely detect eye muscle movement or eyelash movement may not be able to distinguish when the eye is open or closed, and consequently may not be able to measure PERCLOS. Similarly, such devices may not measure other parameters, such as velocity of eyelid closing or opening, acceleration or deceleration characteristics, duration of open or closed eye states, intervals between eye blinks and/or partial versus full eye blinks or eye closures.
Further, infrared cameras or other devices may be used to monitor a driver's awareness, which are typically mounted on the dashboard, roof or other fixed mounting within the user's vehicle. Such devices, however, require that the user maintain constant eye contact with the camera. In addition, they do not monitor eyelid movement if the user looks sideways or downwards, turns around, exits the vehicle or compartment in which he or she is being monitored, or if the camera moves relative to the individual. Further, such cameras may have problems seeing through eyeglasses, sunglasses, or even contact lenses, and may not operate effectively in sunlight.
Accordingly, it is believed that a more effective system and method for monitoring eye and/or eyelid movement would be considered useful.
The present invention is directed to systems and methods for monitoring eye movement. Generally, humans blink at least about 5-30 times per minute, or about 7,000-43,000 times per day. Each involuntary-reflexive blink lasts about 200-300 milliseconds, and generally averaging about 250 milliseconds, amounting to about 1,750-10,800 seconds per day of eye closure due to involuntary blinking. As tiredness or sleepiness occurs, the eye blink gets longer and slower until the eyes begin to close for short term “microsleeps,” i.e., sleep conditions that last for about 3-5 seconds or longer, or for prolonged sleep. The present invention provides systems and methods for monitoring, measuring, and/or responding to eye movement, e.g., nonpurposeful reflexive eyeblinks.
In a preferred embodiment, the system includes an emitter and a sensor in a predetermined relationship with an eye such that the emitter emits light and the sensor detects light from the emitter, the sensor producing a light intensity signal indicating when the eye is open or closed. More preferably, the emitter is directed or aimed at the eyelid and eye, while the sensor detects eyelid-reflected light, since, unlike the eyelid, the eye ball (except the retina, which may cause a “red reflex” under white light conditions or “white pupil” under infrared light) does not reflect substantial light back to the sensor. Circuitry is coupled to the sensor for converting sequential light intensity signals corresponding to eyelid movement received from the sensor into a stream of data, and a processor converts the stream of data into an understandable message.
The circuitry for converting sequential light intensity signals may compare the sequential light intensity signals with a predetermined time threshold to detect voluntary-intentional or unintentional-involuntary sequences of eyelid movements, corresponding, for example, to a predetermined binary code. Memory circuitry may be coupled to the processor for storing the stream of data and/or a communication device, such as a video monitor or synthesized voice module, may be coupled to the processor for communicating the understandable message. In addition, a control system may be coupled to the processor, and the understandable message may include a command for controlling equipment, including electrical or electronic equipment, machinery, or a computer or computer accessory devices coupled to the control system.
The system preferably also includes a transmitter, preferably a radio frequency transmitter, for wireless transmission of the stream of data to a remote location. Alternatively, other forms of wireless transmission, e.g. infrared, as well as hard-wire connections may be used. The processor, as well as the memory circuitry, communication device, and/or control system, may be located at the remote location, and a receiver may be coupled to the processor for receiving the stream of data from the transmitter.
In a preferred form, the system includes a detection device having a frame adapted to be worn on a person's head, e.g., with the frame resting on the bridge of the user's nose and/or ears. The frame has the emitter and sensor thereon such that the emitter and sensor are oriented towards the person's eye when the frame is worn on the person's head. Preferably, the emitter and sensor are a single solid state device, such as a biosensor device, that emits light within a predetermined frequency range, for example infrared light, towards the eye and detects the emitted light reflected off of the eyelid, respectively.
In another preferred embodiment, a system for monitoring a blinking cycle of a person from a remote location is provided that includes an emitter for directing light towards an eye, and a sensor in a predetermined relationship with the emitter for detecting the emitted light reflected off of the eye, the sensor producing an output signal indicating when the eye is open or closed. Depending upon the relative position of the emitter and sensor with respect to the moving eyelid, the emitter light may be reflected off of the eyelid back to the sensor, or diffused by the surface of the eyeball.
A transmitter is coupled to the sensor for wireless transmission of the output signal, and a processor is provided for comparing the output signal to a predetermined threshold to detect when the eyelid is closed for a minimum predetermined duration. A warning indicator may be coupled to the processor, the warning indicator being activated when the processor detects that the eyelid is closed for the minimum predetermined duration. For example, the warning indicator may be an audible buzzer, a visible warning light, a vibrating device, an electrical shock device, a gustatory smell device, or other device that may act as a stimulus to any sensory modality.
Similar to the previous embodiment, a receiver may be provided at the remote location coupled to the processor for receiving the wireless transmission from the transmitter. Memory circuitry may be provided for storing the output signal and/or a processor may be provided for converting the output signal into an understandable message. A communication device may be coupled to the processor for communicating the understandable message.
In another preferred embodiment, a self-contained device for detecting movement of a person's eyelid is provided that includes a frame adapted to be worn on the person's head, an emitter on the frame for directing light towards an eye of the person when the frame is worn, and a sensor on the frame for detecting light from the emitter. The sensor produces an output signal indicating when the eye is open or closed, and a transmitter on the frame is coupled to the sensor for wireless transmission of the output signal to a remote location. The frame may also include a processor for comparing the output signal to a predetermined threshold to detect drowsiness-induced eyelid movement. Similar to the previous embodiments, the emitter and sensor are preferably a solid state biosensor device for emitting and detecting infrared light, or alternatively an array of emitters and/or sensors in a predetermined configuration on the frame, e.g., in a vertical, horizontal, diagonal, or other linear or other geometric array of more than one emitter and/or sensor oriented towards one or both eyes. In particular, an array of emitters and/or sensors allows measurement of eyelid velocity, acceleration and deceleration, and calculation of “PERCLOS.”
The emitter and/or sensors may be affixed to any number of points on the frame, e.g., around the lens and preferably in the nose bridge, or alternatively anywhere along the frame, including near or on the nasal portion of the frame, the attachment of a temple piece of the frame, and/or surface mounted on the lens of an eyeglass. Alternatively, the emitter and/or sensor may be embedded in the lens of an eyeglass, or otherwise such that they operate through the lens. Thus, the emitter(s) and/or sensor(s) are fixed on an eye-frame such that they move with the wearer's head movements, and continuously focus on the user's eyes, whether the user is in a vehicle, outdoors or in any other environment.
Thus, a system in accordance with the present invention may detect eyelid movement of the user, distinguish normal blinks from other voluntary or involuntary eyelid movement, and produce a stream of data. The stream of data may be converted into an understandable message, such as a binary code, a command for controlling a piece of equipment, or an indicator of the user's physical, mental or emotional state. Thus, the system may provide a convenient and/or effective method for voluntary or involuntary communication based simply upon movement of the user's eye.
In accordance with another aspect of the present invention, a system is provided for monitoring movement of a person's eye. The system includes a device configured to be worn on a person's head and an array of emitters on the device for directing light towards an eye of the person when the device is worn. The array of emitters is configured for projecting a reference frame towards the eye. A camera is oriented towards the eye for monitoring movement of the eye relative to the reference frame. The camera may be provided on the device or may be provided remote from the device, but in relatively close proximity to the user.
Preferably, the array of emitters includes a plurality of emitters disposed in a substantially vertical arrangement on the device, and a plurality of emitters disposed in a substantially horizontal arrangement on the device. Thus, the array of emitters may project a focused set of crossed bands towards the eye for dividing a region including the eye into four quadrants.
In addition, the system preferably includes one or more scanning or nonscanning sensors on the device for detecting light from the array of emitters. The one or more sensors produce an output signal indicating when the eye is open or closed, similar to the embodiments described above. More preferably, the sensors include an array of focused sensors in a predetermined relationship with the array of focused emitters for detecting light from the array of emitters that is reflected off of respective portions of the eye or its eyelid. The emitters, because of their fixed position, produce a fixed reflection off of the surface of the eye and eyelid, appearing as a “glint,” i.e., a spot or band of light. Each sensor produces an output signal indicating when the respective portion of the eye is covered or not covered by the eyelid.
The system may also include a processor for correlating the output signal from the one or more sensors with a video signal from the camera for determining the person's level of alertness. The system may also include a warning indicator on the device, the warning indicator being activated when the processor determines a predetermined level of drowsiness has occurred.
Light from the array of emitters may be emitted towards the eye of a user wearing the device to project a reference frame onto the eye. The camera is capable of imaging light produced by the emitters, e.g., in the infrared light range, thereby detecting the projected light as a spot of light, band of light or other “glint.” Movement of the eye relative to the reference frame may be monitored with the camera. A graphical output of the movement monitored by the camera relative to the reference frame may be monitored. For example, infrared light from the emitters may be reflected off of the retina as a “red reflex” under white light, as a “white pupil” under infrared light, or as a dark pupil under subtraction, using methods known to those skilled in the art. The processor, using these methods, may detect movement of the eye's pupil may be measured relative to the reference frame. This movement may be graphically displayed, showing the movement of the eye's pupil relative to the reference frame.
In addition, the output signal from the one or more sensors may be correlated with video signals produced by the camera monitoring movement of the eye relative to the reference frame, thereby determining the person's level of drowsiness.
Other objects and features of the present invention will become apparent from consideration of the following description taken in conjunction with the accompanying drawings.
Turning now to the drawings.
The detection device 30 includes a clamp 27 for attaching to one of the side members 25 and an adjustable arm 31 onto which is mounted an emitter 32 and a sensor 33. Preferably, the emitter 32 and sensor 33 are mounted in a predetermined relationship such that the emitter 32 may emit a signal inwards an eye 300 of a person wearing the eyeglasses 20 and the sensor 33 may detect the signal reflected from the surface of the eye 300 and eyelid 302. As shown in
Alternatively, as shown in
In a preferred form, the emitter 32 and sensor 33 produce and detect continuous or pulsed light, respectively, preferably within the infrared range to minimize distraction or interference with the wearer's normal vision. Preferably, the emitter 32 emits light in pulses at a predetermined frequency and the sensor 33 is configured to detect light pulses at the predetermined frequency. This pulsed operation may reduce energy consumption by the emitter 32 and/or may minimize interference with other light sources. Alternatively, other predetermined frequency ranges of light beyond or within the visible spectrum, such as ultraviolet light, or other forms of energy, such as radio waves, sonic waves and the like, may be used.
The processing box 130 is coupled to the detection device 30 by a cable 34 including one or more wires therein (not shown). As shown in
For example, in a preferred form, the control circuitry 141 controls the emitter 32 to produce a flickering infrared signal pulsed at a predetermined frequency, as high as thousands of pulses per second to as little as about 4-5 pulses per second, and preferably at least about 5-20 pulses per second, thereby facilitating detection of nonpurposeful or purposeful eye-blinks as short as about 200 milliseconds per blink. The sensor 33 may be controlled to detect light pulses only at the predetermined frequency specific to the flicker frequency of the emitter 32. Thus, by synchronizing the emitter 32 and the sensor 33 to the predetermined frequency, the system 10 may be used under a variety of ambient conditions without the output signal 142 being substantially affected by, for example, bright sun light, total darkness, ambient infrared light backgrounds, or other emitters operating at different flicker frequencies. The flicker frequency may be adjusted to maximize the efficient measurement of the number of eye blinks per unit time (e.g. about ten to about twenty eye blinks per minute), the duration of each eye blink (e.g. about 200 milliseconds to about 300 milliseconds), and/or PERCLOS (i.e., the percentage of time that the eyelid is completely or partially closed), or to maximize efficiency of the system, while keeping power consumption to a minimum.
The control circuitry 141 and/or processing box 130 may include manual controls (not shown) for adjusting the frequency, focus, or intensity of the light emitted by the emitter 32, to turn the emitter 32 off and on, to adjust the threshold sensitivity of the sensor 33, and/or to allow for self-focusing with maximal infrared reflection off of a closed eyelid, as will be appreciated by those skilled in the art.
In addition, the processing box 130 also preferably includes a power source 160 for providing power to the emitter 32, the sensor 33, the CPU 144, and/or other components in the processing box 130. The processor box 130 may be powered by a conventional DC battery, e.g., a nine volt battery or a lithium battery. Alternatively, an adapter (not shown) may be connected to the processor box 130, such as a conventional AC adapter or a twelve volt automobile lighter adapter.
Preferably, the CPU 140 includes timer circuitry 146 for comparing the length of individual elements of the output signal 142 to a predetermined threshold to distinguish between normal blinks and other eyelid movement. The timer circuitry 146 may be separate discrete components or may be provided internally within the CPU 140, as will be appreciated by those skilled in the art. The CPU 140 converts the output signal 142 into a stream of data 144 which may be used to communicate to other persons or equipment. For example, the stream of data 144 produced by the CPU 140 may be a binary signal, such as Morse code or ASCI code. Alternatively, the CPU 140 may be capable of producing a synthesized voice signal, a control signal for a piece of equipment, or even a pictorial representation.
To facilitate communication, the processing box 130 may include a variety of output devices for using the stream of data 144. For example, an internal speaker 130 may be provided, which may produce an alarm sound or a synthesized voice. An output port 148 may be provided to which a variety of equipment, such as the video display 50 shown in
The processing box 130 may also include a transmitter 152 coupled to the CPU 144 for wireless communication of the stream of data 144 to a remote location. For example, as shown in
The transmitter 152 may also be coupled to an amplifier (not shown) to allow the stream of data to be transmitted thousands of feet or more. For example, the amplifier and transmitter 152 may communicate via telephone communication lines, satellites and the like, to transmit the stream of data to a remote location miles away from the system. The system may include, or may be coupled to a global positioning system (GPS) for monitoring the location, movement, and state of wakefulness and safety of an individual wearing the detection device 30.
The receiving and processing unit 154 includes a receiver 156, preferably a radio frequency receiver, for receiving a signal 153, including the stream of data, transmitted by the transmitter 152. A processor 158 is coupled to the receiver 156 for translating, storing and/or using the information in the stream of data, the processor 158 being coupled to memory circuitry 160, a communication device 162, and/or a control system 164. For example, the receiving and processing unit 154 may include the memory circuitry 160 therein into which the processor 158 may simply store the stream of data for subsequent retrieval and analysis.
The processor 158 may interpret the stream of data, for example, by converting a binary code in the stream of data into an understandable message, i.e., a series of letters, words and/or commands, and/or may use augmentative communication devices a software (such as KE:NX or Words Plus) to facilitate communication. The resulting message may be displayed on the communication device 162, which may include a video display for displaying text, pictures and/or symbols, a synthesized voice module for providing electronic speech, and the like.
Alternatively, the stream of data may be displayed graphically on a computer of video screen or other electronic display device as a “real time” message signal or numerically (e.g., displaying blink rate, blink duration, PERCLOS, etc.), or displayed graphically similar to an EKG or EEG tracing. In addition, as shown in
In addition, the message may be interpreted by the processor 138 for directing the control system 164 to control one or more pieces of machinery or equipment. For example, the stream of data may include a command to direct the control system 164 to control relay switches or other devices to turn off and on an electrical device, such as an appliance, electrical wheelchair, engine, light, alarm, telephone, television, computer, a tactile vibrating seat, and the like, or to operate an eye-activated computer mouse or other controller.
Alternatively, the processor 158 may use the stream of data to control PC, IBM, Macintosh and other computers and compatible computer software and/or hardware, e.g., to interact with a computer similar to a mouse, a “return” key or a “joystick.” For example, the stream of data may include commands to activate a series of menus from which sub-menus or individual items may be selected, as are used in commercially available special communications software, such as WORDS-PLUS or Ke:NX. The processor 158 may then control, scroll or select items from computer software programs, operate a printer or other peripheral device (e.g., selecting a font, paragraph, tab or other symbol operator, selecting commands, such as “edit,” “find,” “format,” “insert” “help,” or controlling CD-ROM or disc drive operations, and/or other Windows and non-Windows functions).
Alternatively, the receiver 156 may be coupled directly to a variety of devices (not shown), such as radio or television controls, lamps, fans, heaters, motors, remote control vehicles, vehicle monitoring or controlling devices, computers, printers, telephones, lifeline units, electronic toys, or augmentative communication systems, to provide a direct interface between the user and the devices.
During use, the detection device 30 is placed on a user's head, i.e., by putting the eyeglasses 20 on as shown in FIG. 1. The adjustable arm 31 and/or the clamp 27 may be adjusted to optimally orient the emitter 32 and sensor 33 towards the user's eye 300 (shown in
Because of the difference in the reflective characteristics of the surface of the eye 300 itself and the eyelid 302, the intensity of the light reflected off of the eye 300 depends upon whether the eye 300 is open or closed. For example,
The sensor 33 consequently produces a light intensity signal that indicates when the eye 300 is open or closed, i.e., corresponding to the time during which reflected light is not detected or detected, respectively, by the sensor 33. Generally, the intensity of the infrared light reflected from the surface of the eyelid is not substantially affected by skin pigmentation. If it is desired to adjust the intensity of light reflected from the eyelid, foil, glitter, reflective moisturizer creams and the like may be applied to increase reflectivity, or black eye liner, absorptive or deflective creams and the like may be applied to reduce reflectivity.
In one useful application, the detection device 30 may be used to detect impending drowsiness or “micro-sleeps” (i.e., sleep intrusions into wakefulness lasting a few seconds) of a user, with the processing box 130 triggering a warning to alert the user, others in his or her presence, or monitoring equipment of the onset of drowsiness. The threshold of the timer circuitry 146 may be adjusted such that the CPU 140 detects relatively long periods of eye closure, as may occur when a person is falling asleep.
For example, because normal blinks are relatively short, the threshold may be set at a time ranging from close to zero seconds up to several seconds, preferably from about 200 milliseconds to about 300 milliseconds, and most preferably about 250 milliseconds, to distinguish normal blinks from drowsiness-induced eyelid movement. When the CPU 140 detects a drowsiness condition, i.e., detects a high light intensity signal exceeding the predetermined threshold time, it may activate a warning device. The warning device may be included within the processing box 130, such as the speaker 150, or alternatively on the frame, for example, by mounting a warning light (not shown) or an alarm speaker (not shown in
Alternatively, the detection device 30 may be used to unobtrusively record or monitor drowsiness-induced eyelid movement, with the CPU 144 producing a stream of data 144 which the transmitter 152 may transmit to the receiving and processing unit 154 (FIG. 9). For example, the device 30 may be used in conjunction with a vehicle safety system to monitor a driver's level of awareness or attentiveness. The stream of data 144 may be transmitted to a receiving and processing unit 154 mounted in a vehicle, which may store data on the driver's drowsiness and/or may use the data to make decisions and control the vehicle, e.g., adjust the vehicle's speed or even turn the vehicle's engine off. Thus, the detection device 30 may be used to monitor truck drivers, taxi drivers, ship or airline pilots, train conductors or engineers, radar or airport control tower operators, operators of heavy equipment or factory machinery, scuba divers, students, astronauts, entertainment participants or observers, and the like. The signals may be stored and analyzed in real time for trend changes measured over time to predict drowsiness effects of individuals using the device.
The detection device 30 and system 14 may also be used in a medical diagnostic, therapeutic, research or professional setting to monitor the wakefulness, sleep patterns and/or the effects of drugs, which may affect blink rate, blink velocity, blink duration, or PERCLOS of a patient or vehicle operator. Similar to the method just described, the CPU 140 produces a stream of data 144, which the transmitter may send to a remote receiving and processing unit 154, which may store the stream of data 144 in the memory circuitry 160 for later retrieval and analysis by researchers, medical professionals, or safety personnel (e.g., similar to the way in which flight recorder data may be stored in an aircraft's “black box” recorder). The receiving and processing unit 154 may also display the stream of data 144, for example at a nurse's station, as an additional parameter to continually monitor a patient's physical, mental, or emotional condition. The unit 154 may store and/or produce a signal, e.g., by a series of algorithms, that must be responded to within a predetermined time (e.g., performance vigilance monitoring) to prevent false positives and negatives.
A number of medical conditions may be monitored by the detection device 30 and system 14, such as petit mal epilepsy, in which the eyes flutter at a rate of about three cycles per second, grand mal or psychometer seizures, where the eyes may stare or close repetitively in a jerky manner, myoclonic seizures, in which the lids may open and close in a jerky manner, or tics, or other eye movements, such as encountered by people with Tourette's syndrome. The system may be used to monitor g-lock of pilots caused by g-force effects, hypoxemia of passengers or crew in aircraft due to losses in cabin pressure, nitrogen narcosis or “the bends” in divers, or the effects of gases, chemicals, or biological agents on military personnel or other individuals.
The system may also be used to monitor psychological situations, for example, to detect when a person lies (e.g., by closing their eyes when lying), during hypnosis, to monitor attentiveness, the effects of medications, e.g., L-dopa and other anti-Parkinsonian medications or anti-convulsants, drugs, alcohol, toxins, or the effects of hypoxia or ventilation, and the like. Neurological conditions may also be monitored where the innervation or mechanical function of the eyelid may be affected, such as in Parkinson's disease, muscle diseases, e.g., myotonia, myotonic muscular dystrophy, blepharospasm, photophobia or light sensitivity, emcephalopathy, seizures, Bell's palsy, or where the condition may produce eyelid drooping or ptosis, such as third cranial nerve palsy or paresis, brainstem lesions or stroke, tumors, infection, metabolic diseases, trauma, degenerative conditions, e.g., multiple sclerosis, amyotrophic lateral sclerosis, polyneuropathy, myesthenia gravis, botulism, tetanus, tetany, tardive dyskinesia, brainstem encephalitis, and other primary eyelid conditions, such as exophthalmos, thyrotoxicosis or other thyroid conditions.
Similarly, the detector device 30 may be used in biofeedback applications, for example, in biofeedback, hypnosis or psychological therapies of certain conditions (e.g. tic disorders). The detector device 30 may produce a stimulus, e.g. activating a light or speaker, and monitor the user's eyelid movement in anticipation of receiving a response, e.g., a specific sequence of blinks, acknowledging the stimulus within a predetermined time. If the user fails to respond, the processor may store the response, e.g. including response time, and/or may automatically transmit a signal, such as an alarm signal.
In addition, the detection device 30 may be used to monitor individuals in non-medical settings, such as during normal activity in a user's home or elsewhere. For example, individuals with involuntary medical conditions, such as epilepsy or narcolepsy, may be monitored, or other individuals, such as, infants and children, prison inmates, demented patients (e.g., with Alzheimer's disease), law enforcement personnel, military personnel, bank tellers, cashiers, casino workers, students, swing or graveyard shift workers, and the like, may be monitored. Similar application may be applied in a sleep laboratory for monitoring sleep patients to measure parameters, such as onset of sleep, sleep latency, time of eyelid closing or opening, time of awakening during the night, etc., or to animal research where eye blinking may be a factor to be studied. Similarly, the performance and vigilance abilities of the user may be tested and analyzed as a direct function of, or in relationship to, PERCLOS.
When the CPU 140 detects the presence of particular eyelid movement, such as an extensive period of eye closure which may occur, for example, during an epileptic seizure, a syncopal episode, a narcoleptic episode, or when dozing off while driving or working, the CPU 140 may produce an output signal which activates an alarm. Alternatively, the transmitter 152 may send an output signal to shut off equipment being used, to notify medical personnel, such as by automatically activating a telephone to dial emergency services, to signal remote sites, such as police stations, ambulances, vehicle control centers, guardians, and the like.
The system for communication 14 may also find useful application for voluntary communication. A user wearing the detection device 30 may intentionally blink in a predetermined pattern, for example, in Morse code or other blinked code, to communicate an understandable message to people or equipment (e.g., to announce an emergency). The CPU 140 may convert a light intensity signal 142 received from the sensor 33 and corresponding to the blinked code into a stream of data 144, or possibly directly into an understandable message including letters, words and/or commands.
The stream of data 144 may then be displayed on a video display 50 (see
The device may be used in any environment or domain, e.g., through water or other substantially transparent fluids. Further, the device 30 may also be used as an emergency notification and/or discrete security tool. A person who may be capable of normal speech may wear the device 30 in the event of circumstances under which normal communication, i.e., speech, is not a viable option. For example, a bank or retail employee who is being robbed or is otherwise present during the commission of a crime may be able to discretely blink out a preprogrammed warning to notify security or to call law enforcement. Alternatively, a person with certain medical conditions may wear the device in the event that they are physically incapacitated, i.e., are unable to move to call for emergency medical care, but are still able to voluntarily move their eyes. In such cases, a pre-recorded message or identifying data (e.g. name of the user, their location, the nature of the emergency, etc.) may be transmitted to a remote location by a specific set of eyeblink codes or preprogrammed message. In this manner, the detection device 30 may be used to monitor patients in an ICU setting, patients on ventilators, prisoners, elderly or disabled persons, heavy equipment operators, truck drivers, motorists, ship and aircraft pilots, train engineers, radar or airport control tower operators, or as a nonverbal a subliminal tool for communication by military guards, police bank tellers, cashiers, taxi-drivers, and the like. The detection device 30 may also be used as a recreational device, for example, as a children's toy similar to a walkie-talkie or to operate a remote control toy vehicle.
In addition, it may be desirable to have the CPU 140 perform an additional threshold comparison to ensure continued use of the detection device 30. For example, additional timer circuitry may be coupled to the CPU 140 such that the CPU 140 may compare the light intensity signals received from the sensor 33 to a second predetermined threshold provided by the timer circuitry. Preferably, the second predetermined threshold corresponds to a time period during which a person would normally blink. If the CPU 140 fails to detect a normal blink within this time period or if the user fails to respond to a predetermined stimulus (e.g. a blinking light or sound), the CPU 140 may produce a signal, activating the speaker 150 or transmitting a warning using the transmitter 152.
This may be useful, if, for example, the detection device 30 is removed by a perpetrator during commission of a crime, falls off because of the onset of a medical episode, as well as to prevent “false alarms,” or to measure the “state of attentiveness” of the user. Alternatively, performance vigilance tasks may be required of the user to determine whether the signal transmitted is a purposeful or “false alarm” signal, and also for measuring attention or drowsiness levels for purposes of biofeedback, and also to measure compliance of the user wearing the device.
Alternatively, the polarity of the output signal 142 may be reversed such that a stream of data is produced only when the eye is opened, for example, when monitoring patients in a steep lab to measure onset of sleep, sleep latency, time of eyelid closure, etc., or to monitor sleeping prison inmates. For such uses, the CPU 140 may activate an alarm only when an open eye condition is detected, as will be appreciated by those skilled in the art.
Hamamatsu manufactures a variety of infrared emitter and detector devices which may be used for the biosensor device 132, such as Model Nos. L1909, L1915-01, L2791-02, L2792-02, L2959, and 5482-11, or alternatively, a Radio Shack infrared emitter, Model No. 274-142, may be used. Multiple element arrays, e.g., linear optical scanning sensor arrays, appropriate for use with the present invention may be available from Texas Advanced Optoelectronic Solutions, Inc. (TAOS) of Plano, Tex,, such as Model Nos. TSL 201(64 pixels×1 pixel), TSL 202 (128×1), TSL 208 (512×1), TSL 2301 (102×1). These sensors may be used in combination with lens arrays to facilitate focusing of the detected light, such as the Selfoc lens array for line scanning applications made by NSG America, Inc. of Irvine, Calif.
In addition, multiple biosensor devices 132 may be provided on the eyeglasses 20, for example, a pair of biosensor devices 132 may be provided, as shown in
The pair of biosensor devices 132 may allow use of more sophisticated codes by the user, e.g., blinking each eye individually or together, for communicating more effectively or conveniently, as will be appreciated by those skilled in the art. In one form, a blink of one eye could correspond to a “dot,” and the other eye to a “dash” to facilitate use of Morse code. The output signals from each eye could then be interpreted by the CPU 140 and converted into an understandable message.
In another form, a right eye blink (or series of blinks) may cause an electric wheelchair to move to the right, a left eye blink (or series of blinks) may move to the left, two simultaneous right and left eye blinks may cause the wheelchair to move forward, and/or four simultaneous right and left eye blinks may cause the wheelchair to move backward. Similar combinations or sequences of eye blinks may be used to control the on/off function, or volume or channel control of a television, AM/FM radio, VCR, tape recorder or other electronic or electromechanical device, any augmentative communications or controlling device, or any device operable by simple “on/off” switches (e.g., wireless television remote controls single switch television control units, universal remote controllers, single switch multi-appliance units with AC plug/wall outlet or wall switch modules, computer input adapters, lighted signaling buzzer or vibrating signal boxes, switch modules of all types, video game entertainment controller switch modules and switch-controlled electronic toys).
In additional alternatives, one or more lenses or filters may be provided for controlling the light emitted and/or detected by the biosensor device, an individual emitter and/or detector. For example, the angle of the light emitted may be changed with a prism or other lens, or the light may be columnated or focused through a slit to create a predetermined shaped beam of light directed at the eye or to receive the reflected light by the sensor. An array of lenses may be provided that are adjustable to control the shape, e.g. the width, etc., of the beam of light emitted or to adjust the sensitivity of the sensor. The lenses may be encased along with the emitter in plastic and the like, or provided as a separate attachment, as will be appreciated by those skilled in the art.
Turning now to
One of the supports 423 may have a larger size compared to the other support 423, for example, to receive the processor and transmitter circuitry 430 embedded or otherwise mounted thereon. A processor 440, similar to the CPU 140 in the processing box 130 previously described, may be provided on the frame 422, and a power source, such as a lithium battery 460, may be inserted or affixed to the support 423. A radio frequency or other transmitter 452 is provided on the support 423, including an antenna 453, which may be embedded or otherwise fastened along the ear support 423, in the temple piece or elsewhere in the frame 422.
The system 414 may also include manual controls (not shown) on the ear support 423 or elsewhere on the frame 422, for example to turn the power off and on, or to adjust the intensity and/or threshold of the biosensor device 432. Thus, a system for communication 414 may be provided that is substantially self-contained on the frame 422, which may or may not include lenses (not shown) similar to eyeglasses. External cables or wires may be eliminated, thereby providing a more convenient and comfortable system for communication.
In another alternative, shown in
As shown particularly in
The linear array 530 may facilitate measurement of additional parameters related to eyelid movement in addition to mere eye closure. For example, to measure the velocity of the eyelid opening or closing, i.e., the rate of eye closure, the CPU 540 may compare the time delay between the activation of successive sensors 533. In addition, the output signals from the sensors 553 may be processed to measure the percentage of pupil coverage of the eyelid 302, for example, due to partial eye closure, as a function of time, e.g., to monitor when the eye is partially, but not completely, closed, and/or to monitor the percentage of time that the eye is closed (PERCLOS), as shown in
The sensors in the array 633, 733 may be sufficiently sensitive or have sufficient resolution such that they may detect “red reflex” or the equivalent infrared “bright pupil” reflection due to the reflection of light off of the retina through the pupil 301. Thus, the sensors may produce a light intensity signal that includes a substantially zero value, indicating no red reflex or bright pupil, a low output, indicating red reflex or white pupil reflex, and a high output, indicating reflection off of a closed eyelid 302. The red reflex may appear as a bright white light pupil (resulting from infrared light from the emitter(s) reflecting off of the retina when the eyelid is open, or as a dark or “black pupil” if the processor uses subtraction algorithms, as is known in the art. The processor may thereby process the light intensity signals to detect when the pupil 301 is covered by the eyelid 302, i.e., at which point the user cannot see, even though their eye 300 may not be entirely covered by the eyelid 302, generally at a PERCLOS value of about 50-75 percent in primary gaze. Alternatively, as the eyelid, eye, and pupil descend, the sensor(s) may detect a red reflex or bright pupil even through the PERCLOS measurement may be as great as 75-80 percent or more, e.g., where the eye may still see through a narrow slit-like palpebral fissure opening in downward gaze.
In another alternative, the processor and/or transmitter circuitry (such as the CPU 140 in the processor box 130 of
The CPU may selectively add the identification information to the transmitted stream of data 553, or the identification information may be automatically or periodically included in the stream of data 553, thereby allowing the stream of data 553 to be associated with a particular detection device, individual user and/or a specific location. The identification information may be used by the processor, for example, at a remote location, to distinguish between streams of data received from a number of detection devices, which may then be stored, displayed, etc. as previously described. Thus, the detection device may not require users to consciously communicate certain identification or other standard information when the system is used.
As shown in
Alternatively, as shown in
An array of emitters 820 are provided on the frame 812, preferably in a vertical array 820a and a horizontal array 820b. In a preferred embodiment, the emitters 820 are infrared emitters configured to emit pulses at a predetermined frequency, similar to the embodiments described above. The emitters 820 are arranged on the frame such that they project a reference frame 850 onto the region of the user's eye. In a preferred embodiment, the reference frame includes a pair of crossed bands 850a, 850b dividing the region into four quadrants. The intersection of the crossed bands is preferably disposed at a location corresponding substantially to the eye's pupil during primary gaze, i.e., when the user is looking generally straight forward. Alternatively, other reference frames may be provided, generally including a vertical component and a horizontal component.
An array of sensors 822 are also provided on the frame 812 for detecting light from the emitters 820 that is reflected off of the user's eyelid. The sensors 822 preferably generate output signals having an intensity identifying whether the eyelid is closed or open, similar to the embodiments described above. Preferably, the sensors 822 are disposed adjacent to respective emitters 820 for detecting light reflected off of respective portions of the eyelid. Alternatively, sensors 822 may only be provided in a vertical array, e.g., along the bridge piece 814, for monitoring the amount of eyelid closure, similar to the embodiments described above. In a further alternative, the emitters 820 and sensors 822 may be solid state biosensors (not shown) that provide both the emitting and sensing functions in a single device.
Circuitry may be provided for measuring PERCLOS or other parameters using the signals generated by the array of sensors. For example,
One of the ear supports 816 may include a panel 818 for mounting a controller or other processor 842, a transmitter 844, an antenna 845, and a battery 846. Preferably, the processor 840 842 is coupled to the emitters 820, the sensors 822, and/or the camera 830 for controlling their operation. The transmitter 844 may be coupled to the processor 842 for receiving the output signals from the sensors 822 and/or the video signals from the camera 830, e.g., to transmit the signals to a remote location, as described below. Alternatively, the transmitter 844 may be coupled directly to output leads from the sensors 822 and the camera 830. The frame 812 may also include manual controls (not shown), e.g., on the ear support 816, for example, to turn the power off and on, or to adjust the intensity and/or threshold of the emitters 820, the sensors 822, and/or the camera 830.
If desired, the system 810 may also include one or more additional sensors on the frame 812. The sensors may be coupled to the processor 842 and/or to the transmitter 844 so that the signals from the sensors may be monitored, recorded, and/or transmitted to a remote location. For example, one or more position sensors 852a, 852b may be provided, e.g., for determining the spatial orientation of the frame 812, and consequently the user's head. For example, actigraphic sensors may be provided to measure tilt or movement of the head, e.g., to monitor whether the user's head is drooping forward or tilting to the side. Acoustic sensors, e.g., a microphone 854 may be provided for detecting environmental noise or sounds produced by the user.
In addition or alternatively, the frame 812 may include one or more sensors for measuring one or more physical characteristics of the user. For example, EEG electrodes 856 may be provided on the ear support 816, above or below the nasion, and/or other region that may contact the patient's skin to measure brain activity, e.g., waking, drowsy, or other sleep-related brain activity. An EKG electrode (not shown) may be provided that is capable of measuring cardiac activity through a skin contact site. A pulse sensor (not shown) may be used to measure cardiovascular pulsations, or an oximetry sensor 858 may be used to measure oxygen saturation levels. A thermistor or other sensor may measure of respiratory air flow, e.g., through the user's nose. A thermister, thermocouple, or other temperature sensor (not shown) may be provided for measuring the user's skin temperature. A sweat detector (not shown) may be provided for measuring moisture on the user's skin.
In addition, the system 810 may include one or more feedback devices on the frame 812. These devices may provide feedback to the user, e.g., to alert and/or wake the user, when a predetermined condition is detected, e.g., a state of drowsiness or lack of consciousness. The feedback devices may be coupled to the processor 842, which may control their activation. For example, a mechanical vibrator device 860 may be provided at a location that may contact the user, e.g., on the ear support 816, that may provide tactile vibrating stimuli through skin contact. An electrode (not shown) may be provided that may produce relatively low power electrical stimuli. A light emitter, such as one or more LED's may provided at desired locations, e.g., above the bridge piece 814. Alternatively, audio devices 862, such as a buzzer or other alarm, may be provided, similar to the previous embodiments. In a further alternative, aroma-emitters may be provided on the frame 810 812, e.g., on or adjacent to the bridge piece 814.
Alternatively, the feedback devices may be provided separate from the frame, but located in a manner capable of providing a feedback response to the user. For example, audio, visual, tactile (e.g., vibrating seat), or olfactory emitters may be provided in the proximity of the user, such as any of the devices described above. In a further alternative, heat or cold generating devices may be provided that are capable of producing thermal stimuli to the user, e.g., a remotely controlled fan or air conditioning unit.
The system 810 may also include components that are remote from the frame 812, similar to the embodiments described above. For example, the system 810 may include a receiver, a processor, and/or a display (not shown) at a remote location from the frame 812, e.g., in the same room, at a nearby monitoring station, or at a more distant location. The receiver may receive signals transmitted by the transmitter 842, including output signals from the sensors 822 or any of the other sensors provided on the frame 812 and/or the video signals from the camera 830.
A processor may be coupled to the receiver for analyzing signals from the components on the frame 812, e.g., to prepare the signals for graphical display. For example, the processor may prepare the video signals from the camera 830 for display on a monitor, thereby allowing personal monitoring of the user. Simultaneously, other parameters may be displayed, either on a single monitor or on separate displays. For example,
In a further alternative, the processor may automatically process the signals to monitor or study the user's behavior. For example, the processor may use the output signals to monitor various parameters related to eye movement, such as eye blink duration (EBD), eye blink frequency, eye blink velocity, eye blink acceleration, interblink duration (IBD), PERCLOS, PEROP (percentage eyelid is open), and the like.
The video signals from the camera 830 may be processed to monitor various eye parameters, such as pupillary size, location, e.g., within the four quadrant defined by the crossed bands 850, eye tracking movement, eye gaze distance, and the like. For example, because the camera 830 is capable of detecting the light emitted by the emitters 822, the camera 830 may detect a reference frame projected onto the region of the user's eye by the emitters.
Because the emitters 822 are fixed to the frame 812, the reference frame 850 remains substantially stationary. Thus, the processor may determine the location of the pupil in terms of orthogonal coordinates (e.g., x-y or angle-radius) relative to the reference frame 850. Alternatively, if the reference frame is eliminated, the location of the pupil may be determined relative to any stationary “glint” point on the user's eye. For example, the camera 830 itself may project a point of light onto the eye that may be reflected and detected by the camera. This “glint” point remains substantially stationary since the camera 830 is fixed to the frame 812.
In addition, the video signals from a remote camera that may view the user's face from a distance may be used to monitor various facial measures, such as facial expression, yawning frequency, and the like, in addition to or alternatively, the project instead of the projected light reference frame from the emitters. In addition or alternatively, the parameters from other sensors may be processed and correlated, such as head orientation, tilt, body movement, physiological parameters, and the like. Preferably, the processor may correlate these parameters to generate a composite fatigue index (CFI) that is a function of two or more of these parameters. When a predetermined CFI is detected, the system 810 may activate an alarm or other notice to the user and/or to another party at a remote location. Thus, the system 810 may provide a more effective way to monitor the user's fatigue, drowsiness, alertness, mental state, and the like. In a further alternative, the system 810 may be used to generate predetermined outputs, e.g., to activate or deactivate equipment, such as a vehicle being operated by the user when a predetermined condition, e.g., CFI value, is determined by the system 810.
Alternatively, the processor may be provided on the frame 812, e.g. as part of processor 842, for monitoring the parameters for a predetermined event, such as a predetermined CFI value, to occur. Although only a single lens and set of emitters, sensors, and cameras are shown, it will be appreciated that another set may be provided for the other eye of the user of the system 810. In a further alternative, the eye tracking parameters described above may be monitored by a remote camera, e.g., in a fixed position in front of the user, such as the dashboard of a vehicle and the like. The remote camera may be coupled to the processor, either directly or via its own transmitter, as will be appreciated by those skilled in the art.
Thus, a system in accordance with the present invention may monitor or detect one or more parameters, such as those listed below in Table 1.
Potential Biometric Measures
Percentage of time (t) and
Eye Tracking Movements (ETM)
the amount palpebral
including Directional Nystagmus
fissure is opened
Eye Gaze Distance (EGD) and
(PEROP-t, -d, -dt),
Eye Movement Distance
(PERCLOS-t, -d, -dt),
Eye Movement Velocity (EMV)
Eye Movement Acceleration (EMA)
Eye Blink Duration (EBD)
and Deceleration (EMD)
Eye Blink Frequency (EBF)
Eye Movement Frequency (EMF)
Eye Blink Velocity (EBV)
Phoria/eye Drift Measures (PDM)
Eye Blink Acceleration
HEAD ORIENTATION MEASURES
Head Direction or Orientation
Interblink duration (IBD)
HEAD MOVEMENT MEASURES
Eye blink flurries
Head Nodding Frequency (HNF)
Head Tilt (HT)
Pupillary Appearance or
OTHER NON-VIDEO SENSOR METRICS
Disappearance (with eyelid
EEG, EKG, pulse, oxygen
saturation, respiration rate,
Pupillary Size Measurement
body temp, skin conductance,
actigraphic movements, head
Presence and quality of
Dilation or Construction
While the invention is susceptible to various modifications, and alternative forms, specific examples thereof have been shown in the drawings and are herein described in detail. It should be understood, however, that the invention is not to be limited to the particular forms or methods disclosed, but to the contrary, the invention is to cover all modifications, equivalents and alternatives falling within the spirit and scope of the appended claims.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US3863243 *||19 Jan 1972||28 Jan 1975||Skolnick Max||Sleep inhibiting alarm|
|US4953111 *||11 Feb 1988||28 Aug 1990||Omron Tateisi Electronics Co.||Doze detector|
|US4967186 *||18 Aug 1989||30 Oct 1990||Ariold Ludmirsky||Method and apparatus for fatigue detection|
|US4988183 *||12 Jun 1989||29 Jan 1991||Konan Camera Research Institute, Inc.||Eye movement inspection device|
|US5402109 *||29 Apr 1993||28 Mar 1995||Mannik; Kallis H.||Sleep prevention device for automobile drivers|
|US5570698 *||2 Jun 1995||5 Nov 1996||Siemens Corporate Research, Inc.||System for monitoring eyes for detecting sleep behavior|
|US5682144 *||20 Nov 1995||28 Oct 1997||Mannik; Kallis Hans||Eye actuated sleep prevention devices and other eye controlled devices|
|US5689241 *||31 May 1996||18 Nov 1997||Clarke, Sr.; James Russell||Sleep detection and driver alert apparatus|
|US5748113 *||19 Aug 1996||5 May 1998||Torch; William C.||Method and apparatus for communication|
|US5867587 *||19 May 1997||2 Feb 1999||Northrop Grumman Corporation||Impaired operator detection and warning system employing eyeblink analysis|
|US6087941 *||8 Sep 1999||11 Jul 2000||Ferraz; Mark||Warning device for alerting a person falling asleep|
|US6097295 *||28 Jan 1999||1 Aug 2000||Daimlerchrysler Ag||Apparatus for determining the alertness of a driver|
|US6163281 *||24 Jun 1998||19 Dec 2000||Torch; William C.||System and method for communication using eye movement|
|US6246344 *||25 Nov 1997||12 Jun 2001||William C. Torch||Method and apparatus for voluntary communication|
|US6334683 *||23 Feb 2001||1 Jan 2002||Lasersight Technologies, Inc.||Eye illumination system and method|
|US6864473 *||7 Dec 2000||8 Mar 2005||The United States Of America As Represented By The United States National Aeronautics And Space Administration||Dynamic optical filtration|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US7369951 *||25 Feb 2005||6 May 2008||Board Of Trustees Of Michigan State University||Digital, self-calibrating proximity switch|
|US7758185||11 Feb 2008||20 Jul 2010||Lewis Scott W||Digital Eyewear|
|US7918556||18 Nov 2009||5 Apr 2011||Lewis Scott W||Digital eyewear|
|US8337404||1 Oct 2010||25 Dec 2012||Flint Hills Scientific, Llc||Detecting, quantifying, and/or classifying seizures using multimodal data|
|US8353594||1 Apr 2011||15 Jan 2013||Lewis Scott W||Digital eyewear|
|US8382667||29 Apr 2011||26 Feb 2013||Flint Hills Scientific, Llc||Detecting, quantifying, and/or classifying seizures using multimodal data|
|US8452387||20 Sep 2010||28 May 2013||Flint Hills Scientific, Llc||Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex|
|US8562536||29 Apr 2010||22 Oct 2013||Flint Hills Scientific, Llc||Algorithm for detecting a seizure from cardiac data|
|US8571643||16 Sep 2010||29 Oct 2013||Flint Hills Scientific, Llc||Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex|
|US8641646||30 Jul 2010||4 Feb 2014||Cyberonics, Inc.||Seizure detection using coordinate data|
|US8649871||30 Apr 2010||11 Feb 2014||Cyberonics, Inc.||Validity test adaptive constraint modification for cardiac data used for detection of state changes|
|US8684921||15 May 2012||1 Apr 2014||Flint Hills Scientific Llc||Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis|
|US8696113||15 Mar 2013||15 Apr 2014||Percept Technologies Inc.||Enhanced optical and perceptual digital eyewear|
|US8725239||25 Apr 2011||13 May 2014||Cyberonics, Inc.||Identifying seizures using heart rate decrease|
|US8733927||12 Aug 2013||27 May 2014||Percept Technologies Inc.||Enhanced optical and perceptual digital eyewear|
|US8733928||12 Aug 2013||27 May 2014||Percept Technologies Inc.||Enhanced optical and perceptual digital eyewear|
|US8831732||30 Apr 2010||9 Sep 2014||Cyberonics, Inc.||Method, apparatus and system for validating and quantifying cardiac beat data quality|
|US8852100||25 Feb 2013||7 Oct 2014||Flint Hills Scientific, Llc||Detecting, quantifying, and/or classifying seizures using multimodal data|
|US8888702||3 Dec 2012||18 Nov 2014||Flint Hills Scientific, Llc||Detecting, quantifying, and/or classifying seizures using multimodal data|
|US8945006||24 Feb 2014||3 Feb 2015||Flunt Hills Scientific, LLC||Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis|
|US8948855||21 May 2013||3 Feb 2015||Flint Hills Scientific, Llc||Detecting and validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex|
|US9010929||11 Jan 2013||21 Apr 2015||Percept Technologies Inc.||Digital eyewear|
|US9020582||30 Sep 2013||28 Apr 2015||Flint Hills Scientific, Llc||Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex|
|US9033502||15 Mar 2012||19 May 2015||Sensomotoric Instruments Gesellschaft Fur Innovative Sensorik Mbh||Optical measuring device and method for capturing at least one parameter of at least one eye wherein an illumination characteristic is adjustable|
|US9086567 *||6 Jan 2005||21 Jul 2015||Semiconductor Energy Laboratory Co., Ltd.||Display system|
|US9107622||15 Mar 2012||18 Aug 2015||Sensomotoric Instruments Gesellschaft Fur Innovative Sensorik Mbh||Optical measuring device and system|
|US9116545 *||21 Mar 2012||25 Aug 2015||Hayes Solos Raffle||Input detection|
|US9128522||17 Jul 2012||8 Sep 2015||Google Inc.||Wink gesture input for a head-mountable device|
|US9201244||3 Feb 2015||1 Dec 2015||Semiconductor Energy Laboratory Co., Ltd.||Goggle type display system|
|US9201512||16 Jul 2012||1 Dec 2015||Google Inc.||Proximity sensing for input detection|
|US9220910||7 Jan 2014||29 Dec 2015||Cyberonics, Inc.||Seizure detection using coordinate data|
|US9235064||17 Mar 2015||12 Jan 2016||Percept Technologies Inc.||Digital eyewear|
|US9239473||17 Mar 2015||19 Jan 2016||Percept Technologies Inc.||Digital eyewear|
|US9241647||21 Oct 2013||26 Jan 2016||Cyberonics, Inc.||Algorithm for detecting a seizure from cardiac data|
|US9244293||17 Mar 2015||26 Jan 2016||Percept Technologies Inc.||Digital eyewear|
|US9265458||4 Dec 2012||23 Feb 2016||Sync-Think, Inc.||Application of smooth pursuit cognitive testing paradigms to clinical drug development|
|US9380976||11 Mar 2013||5 Jul 2016||Sync-Think, Inc.||Optical neuroinformatics|
|US9402550||29 Apr 2011||2 Aug 2016||Cybertronics, Inc.||Dynamic heart rate threshold for neurological event detection|
|US9504390||13 Sep 2013||29 Nov 2016||Globalfoundries Inc.||Detecting, assessing and managing a risk of death in epilepsy|
|US9658473||5 Jan 2015||23 May 2017||Percept Technologies Inc||Enhanced optical and perceptual digital eyewear|
|US9700256||7 Dec 2015||11 Jul 2017||Cyberonics, Inc.||Algorithm for detecting a seizure from cardiac data|
|US20050116882 *||6 Jan 2005||2 Jun 2005||Semiconductor Energy Laboratory Co., Ltd.||Goggle type display system|
|US20050209828 *||25 Feb 2005||22 Sep 2005||Blosser Stephen R||Digital, self-calibrating proximity switch|
|US20070081123 *||7 Oct 2005||12 Apr 2007||Lewis Scott W||Digital eyewear|
|US20080129955 *||11 Feb 2008||5 Jun 2008||Lewis Scott W||Digital eyewear|
|US20100066972 *||18 Nov 2009||18 Mar 2010||Scott W. Lewis||Digital eyewear|
|US20140078283 *||15 Mar 2012||20 Mar 2014||Sensomotoric Instruments Gesellschaft Fur Innovative Sensorik Mbh||Method for determining at least one parameter of two eyes by setting data rates and optical measuring device|
|US20140242560 *||17 Feb 2014||28 Aug 2014||Emotient||Facial expression training using feedback from automatic facial expression recognition|
|US20150182116 *||30 Dec 2013||2 Jul 2015||Google Inc.||Hands-Free Interface|
|US20150305667 *||10 Apr 2015||29 Oct 2015||Case Western Reserve University||Low Frequency Non-Invasive Sensorial Stimulation For Seizure Control|
|US20160343229 *||18 May 2015||24 Nov 2016||Frank Colony||Vigilance detection method and apparatus|
|EP2499960A1||13 Jul 2011||19 Sep 2012||SensoMotoric Instruments GmbH||Method for determining at least one parameter of two eyes by setting data rates and optical measuring device|
|EP2499961A1||13 Jul 2011||19 Sep 2012||SensoMotoric Instruments GmbH||Spectacle device with an adjustable field of view and method|
|EP2499962A1||13 Jul 2011||19 Sep 2012||SensoMotoric Instruments GmbH||Optical measuring device and method for capturing at least one parameter of at least one eye wherein an illumination characteristic is adjustable|
|EP2499964A1||13 Jul 2011||19 Sep 2012||SensoMotoric Instruments GmbH||Optical measuring device and system|
|EP2923638A1||13 Jul 2011||30 Sep 2015||SensoMotoric Instruments Gesellschaft für innovative Sensorik mbH||Optical measuring device and system|
|WO2012126808A1||15 Mar 2012||27 Sep 2012||Sensomotoric Instruments Gmbh||Method for determining at least one parameter of two eyes by setting data rates and optical measuring device|
|WO2012126809A1||15 Mar 2012||27 Sep 2012||Sensomotoric Instruments Gmbh||Optical measuring device and system|
|WO2012126811A1||15 Mar 2012||27 Sep 2012||Sensomotoric Instruments Gmbh||Spectacle device with an adjustable field of view and method|
|U.S. Classification||340/575, 340/576, 340/573.1, 382/117, 600/558|
|International Classification||A61B3/113, A61B5/11, A61B5/16, G01S17/00, A61B5/00, G08B23/00|
|Cooperative Classification||A61B3/10, A61B5/4094, A61M2205/3592, G01S17/88, G08B21/06, A61M2230/10, A61M2021/0083, A61M2021/0044, G01S17/00, G01S7/481, A61B5/486, A61B5/16, A61M2230/06, A61B5/1103, A61M2205/3569, G08B25/016, A61B3/0066, A61B3/113, A61M2230/42, A61M21/02, G06K9/0061, G06K9/00845, A61B5/6821, A61B5/6803, A61B2562/043, A61B2503/22|
|European Classification||A61B3/00C9, G01S17/88, A61M21/02, A61B5/16, A61B5/11F, A61B3/113, G01S17/00|
|7 Oct 2008||CC||Certificate of correction|
|7 Aug 2013||AS||Assignment|
Owner name: EYEFLUENCE, INC., NEVADA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:EYE-COM CORPORATION;REEL/FRAME:030964/0386
Effective date: 20130806
Owner name: EYE-COM CORPORATION, NEVADA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:TORCH, WILLIAM C., DR.;REEL/FRAME:030964/0128
Effective date: 20130328