US8219201B2 - Smooth muscle controller for controlling the level of a chemical in the blood stream - Google Patents
Smooth muscle controller for controlling the level of a chemical in the blood stream Download PDFInfo
- Publication number
- US8219201B2 US8219201B2 US11/736,183 US73618307A US8219201B2 US 8219201 B2 US8219201 B2 US 8219201B2 US 73618307 A US73618307 A US 73618307A US 8219201 B2 US8219201 B2 US 8219201B2
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- US
- United States
- Prior art keywords
- preferred
- electrodes
- electric field
- tract
- muscle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related, expires
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36071—Pain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/205—Applying electric currents by contact electrodes continuous direct currents for promoting a biological process
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36114—Cardiac control, e.g. by vagal stimulation
- A61N1/36117—Cardiac control, e.g. by vagal stimulation for treating hypertension
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
- A61N1/36564—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by blood pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Electrotherapy Devices (AREA)
- Transplanting Machines (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Paper (AREA)
- Massaging Devices (AREA)
- Percussion Or Vibration Massage (AREA)
- Forklifts And Lifting Vehicles (AREA)
Abstract
Description
Claims (21)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/736,183 US8219201B2 (en) | 1997-07-16 | 2007-04-17 | Smooth muscle controller for controlling the level of a chemical in the blood stream |
US11/932,881 US8805507B2 (en) | 1997-07-16 | 2007-10-31 | Methods for controlling labor and treating menstrual cramps in uterine muscle |
US11/932,963 US7966071B2 (en) | 1997-07-16 | 2007-10-31 | Method and apparatus for regulating glucose level |
US11/932,812 US7765008B2 (en) | 1997-07-16 | 2007-10-31 | Method of controlling blood pressure |
US14/332,700 US9265930B2 (en) | 1997-07-16 | 2014-07-16 | Methods and devices for modifying vascular parameters |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IL1997/000243 WO1999003533A1 (en) | 1997-07-16 | 1997-07-16 | Smooth muscle controller |
US09/481,253 US6571127B1 (en) | 1997-07-16 | 2000-01-11 | Method of increasing the motility of a GI tract |
US10/282,968 US7221978B2 (en) | 1997-07-16 | 2002-10-29 | Smooth muscle controller |
US11/736,183 US8219201B2 (en) | 1997-07-16 | 2007-04-17 | Smooth muscle controller for controlling the level of a chemical in the blood stream |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/282,968 Division US7221978B2 (en) | 1997-07-16 | 2002-10-29 | Smooth muscle controller |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/932,963 Continuation US7966071B2 (en) | 1997-07-16 | 2007-10-31 | Method and apparatus for regulating glucose level |
US11/932,881 Continuation US8805507B2 (en) | 1997-07-16 | 2007-10-31 | Methods for controlling labor and treating menstrual cramps in uterine muscle |
US11/932,812 Continuation US7765008B2 (en) | 1997-07-16 | 2007-10-31 | Method of controlling blood pressure |
Publications (2)
Publication Number | Publication Date |
---|---|
US20070185540A1 US20070185540A1 (en) | 2007-08-09 |
US8219201B2 true US8219201B2 (en) | 2012-07-10 |
Family
ID=11062008
Family Applications (9)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/481,253 Expired - Lifetime US6571127B1 (en) | 1997-07-16 | 2000-01-11 | Method of increasing the motility of a GI tract |
US10/282,968 Expired - Fee Related US7221978B2 (en) | 1997-07-16 | 2002-10-29 | Smooth muscle controller |
US10/282,639 Expired - Lifetime US6947792B2 (en) | 1997-07-16 | 2002-10-29 | Smooth muscle controller |
US10/282,959 Expired - Fee Related US7120497B2 (en) | 1997-07-16 | 2002-10-29 | Smooth muscle controller |
US11/736,183 Expired - Fee Related US8219201B2 (en) | 1997-07-16 | 2007-04-17 | Smooth muscle controller for controlling the level of a chemical in the blood stream |
US11/932,963 Expired - Fee Related US7966071B2 (en) | 1997-07-16 | 2007-10-31 | Method and apparatus for regulating glucose level |
US11/932,881 Expired - Fee Related US8805507B2 (en) | 1997-07-16 | 2007-10-31 | Methods for controlling labor and treating menstrual cramps in uterine muscle |
US11/932,812 Expired - Fee Related US7765008B2 (en) | 1997-07-16 | 2007-10-31 | Method of controlling blood pressure |
US14/332,700 Expired - Fee Related US9265930B2 (en) | 1997-07-16 | 2014-07-16 | Methods and devices for modifying vascular parameters |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/481,253 Expired - Lifetime US6571127B1 (en) | 1997-07-16 | 2000-01-11 | Method of increasing the motility of a GI tract |
US10/282,968 Expired - Fee Related US7221978B2 (en) | 1997-07-16 | 2002-10-29 | Smooth muscle controller |
US10/282,639 Expired - Lifetime US6947792B2 (en) | 1997-07-16 | 2002-10-29 | Smooth muscle controller |
US10/282,959 Expired - Fee Related US7120497B2 (en) | 1997-07-16 | 2002-10-29 | Smooth muscle controller |
Family Applications After (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/932,963 Expired - Fee Related US7966071B2 (en) | 1997-07-16 | 2007-10-31 | Method and apparatus for regulating glucose level |
US11/932,881 Expired - Fee Related US8805507B2 (en) | 1997-07-16 | 2007-10-31 | Methods for controlling labor and treating menstrual cramps in uterine muscle |
US11/932,812 Expired - Fee Related US7765008B2 (en) | 1997-07-16 | 2007-10-31 | Method of controlling blood pressure |
US14/332,700 Expired - Fee Related US9265930B2 (en) | 1997-07-16 | 2014-07-16 | Methods and devices for modifying vascular parameters |
Country Status (12)
Country | Link |
---|---|
US (9) | US6571127B1 (en) |
EP (2) | EP1779890B8 (en) |
JP (1) | JP4102545B2 (en) |
KR (1) | KR20010021797A (en) |
AT (2) | ATE353689T1 (en) |
AU (1) | AU3458197A (en) |
CA (1) | CA2296632A1 (en) |
DE (2) | DE69739334D1 (en) |
ES (1) | ES2283020T3 (en) |
IL (1) | IL133902A0 (en) |
WO (1) | WO1999003533A1 (en) |
ZA (1) | ZA976341B (en) |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9526648B2 (en) | 2010-06-13 | 2016-12-27 | Synerz Medical, Inc. | Intragastric device for treating obesity |
US9956393B2 (en) | 2015-02-24 | 2018-05-01 | Elira, Inc. | Systems for increasing a delay in the gastric emptying time for a patient using a transcutaneous electro-dermal patch |
US10010439B2 (en) | 2010-06-13 | 2018-07-03 | Synerz Medical, Inc. | Intragastric device for treating obesity |
US10118035B2 (en) | 2015-02-24 | 2018-11-06 | Elira, Inc. | Systems and methods for enabling appetite modulation and/or improving dietary compliance using an electro-dermal patch |
US10335302B2 (en) | 2015-02-24 | 2019-07-02 | Elira, Inc. | Systems and methods for using transcutaneous electrical stimulation to enable dietary interventions |
US10376145B2 (en) | 2015-02-24 | 2019-08-13 | Elira, Inc. | Systems and methods for enabling a patient to achieve a weight loss objective using an electrical dermal patch |
US10413436B2 (en) | 2010-06-13 | 2019-09-17 | W. L. Gore & Associates, Inc. | Intragastric device for treating obesity |
US10420665B2 (en) | 2010-06-13 | 2019-09-24 | W. L. Gore & Associates, Inc. | Intragastric device for treating obesity |
US10765863B2 (en) | 2015-02-24 | 2020-09-08 | Elira, Inc. | Systems and methods for using a transcutaneous electrical stimulation device to deliver titrated therapy |
US10779980B2 (en) | 2016-04-27 | 2020-09-22 | Synerz Medical, Inc. | Intragastric device for treating obesity |
US10864367B2 (en) | 2015-02-24 | 2020-12-15 | Elira, Inc. | Methods for using an electrical dermal patch in a manner that reduces adverse patient reactions |
US11957895B2 (en) | 2015-02-24 | 2024-04-16 | Elira, Inc. | Glucose-based modulation of electrical stimulation to enable weight loss |
Families Citing this family (365)
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US9289618B1 (en) | 1996-01-08 | 2016-03-22 | Impulse Dynamics Nv | Electrical muscle controller |
US7167748B2 (en) | 1996-01-08 | 2007-01-23 | Impulse Dynamics Nv | Electrical muscle controller |
JP4175662B2 (en) | 1996-01-08 | 2008-11-05 | インパルス ダイナミクス エヌ.ヴイ. | Electric muscle control device |
US8825152B2 (en) | 1996-01-08 | 2014-09-02 | Impulse Dynamics, N.V. | Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue |
US8321013B2 (en) * | 1996-01-08 | 2012-11-27 | Impulse Dynamics, N.V. | Electrical muscle controller and pacing with hemodynamic enhancement |
US9713723B2 (en) | 1996-01-11 | 2017-07-25 | Impulse Dynamics Nv | Signal delivery through the right ventricular septum |
US7908003B1 (en) | 1996-08-19 | 2011-03-15 | Mr3 Medical Llc | System and method for treating ischemia by improving cardiac efficiency |
US7440800B2 (en) * | 1996-08-19 | 2008-10-21 | Mr3 Medical, Llc | System and method for managing detrimental cardiac remodeling |
US7840264B1 (en) | 1996-08-19 | 2010-11-23 | Mr3 Medical, Llc | System and method for breaking reentry circuits by cooling cardiac tissue |
US8447399B2 (en) * | 1996-08-19 | 2013-05-21 | Mr3 Medical, Llc | System and method for managing detrimental cardiac remodeling |
DE69739334D1 (en) | 1997-07-16 | 2009-05-07 | Metacure N V | Device for controlling a smooth muscle |
WO2000053257A1 (en) | 1999-03-05 | 2000-09-14 | Impulse Dynamics Nv | Blood glucose level control |
US7006871B1 (en) | 1997-07-16 | 2006-02-28 | Metacure N.V. | Blood glucose level control |
DE69833665T2 (en) * | 1997-08-08 | 2006-11-09 | Duke University | COMPOSITIONS FOR SIMPLIFYING SURGICAL PROCEDURES |
US6463323B1 (en) | 1998-11-12 | 2002-10-08 | Em Vascular, Inc. | Electrically mediated angiogenesis |
US6152882A (en) * | 1999-01-26 | 2000-11-28 | Impulse Dynamics N.V. | Apparatus and method for chronic measurement of monophasic action potentials |
EP1825880B1 (en) | 1999-03-05 | 2016-05-11 | Metacure Limited | Blood glucose level control |
US9101765B2 (en) | 1999-03-05 | 2015-08-11 | Metacure Limited | Non-immediate effects of therapy |
US8346363B2 (en) * | 1999-03-05 | 2013-01-01 | Metacure Limited | Blood glucose level control |
WO2006073671A1 (en) | 2004-12-09 | 2006-07-13 | Impulse Dynamics Nv | Protein activity modification |
US8666495B2 (en) | 1999-03-05 | 2014-03-04 | Metacure Limited | Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar |
US8700161B2 (en) | 1999-03-05 | 2014-04-15 | Metacure Limited | Blood glucose level control |
US8019421B2 (en) | 1999-03-05 | 2011-09-13 | Metacure Limited | Blood glucose level control |
US6370430B1 (en) | 1999-03-25 | 2002-04-09 | Impulse Dynamics N.V. | Apparatus and method for controlling the delivery of non-excitatory cardiac contractility modulating signals to a heart |
US6263242B1 (en) | 1999-03-25 | 2001-07-17 | Impulse Dynamics N.V. | Apparatus and method for timing the delivery of non-excitatory ETC signals to a heart |
US6355425B1 (en) * | 1999-03-26 | 2002-03-12 | Billups-Rothenberg, Inc. | Mutations associated with iron disorders |
US6292704B1 (en) | 1999-05-25 | 2001-09-18 | Impulse Dynamics N. V. | High capacitance myocardial electrodes |
US7171263B2 (en) | 1999-06-04 | 2007-01-30 | Impulse Dynamics Nv | Drug delivery device |
US7092753B2 (en) | 1999-06-04 | 2006-08-15 | Impulse Dynamics Nv | Drug delivery device |
US7190997B1 (en) | 1999-06-04 | 2007-03-13 | Impulse Dynamics Nv | Drug delivery device |
US6233487B1 (en) | 1999-06-08 | 2001-05-15 | Impulse Dynamics N.V. | Apparatus and method for setting the parameters of an alert window used for timing the delivery of ETC signals to a heart under varying cardiac conditions |
US6223072B1 (en) | 1999-06-08 | 2001-04-24 | Impulse Dynamics N.V. | Apparatus and method for collecting data useful for determining the parameters of an alert window for timing delivery of ETC signals to a heart under varying cardiac conditions |
AUPQ202699A0 (en) * | 1999-08-04 | 1999-08-26 | University Of Melbourne, The | Prosthetic device for incontinence |
AU6465400A (en) * | 1999-08-04 | 2001-03-05 | Impulse Dynamics N.V. | Inhibition of action potentials |
US6464628B1 (en) | 1999-08-12 | 2002-10-15 | Obtech Medical Ag | Mechanical anal incontinence |
US6482145B1 (en) | 2000-02-14 | 2002-11-19 | Obtech Medical Ag | Hydraulic anal incontinence treatment |
US6471635B1 (en) | 2000-02-10 | 2002-10-29 | Obtech Medical Ag | Anal incontinence disease treatment with controlled wireless energy supply |
US6360126B1 (en) | 1999-08-20 | 2002-03-19 | Impulse Dynamics N.V. | Apparatus and method for controlling the delivery of contractility modulating non-excitatory signals to the heart |
US6556872B2 (en) | 1999-08-24 | 2003-04-29 | Ev Vascular, Inc. | Therapeutic device and method for treating diseases of cardiac muscle |
US6560489B2 (en) | 1999-08-24 | 2003-05-06 | Em Vascular, Inc. | Therapeutic device and method for treating diseases of cardiac muscle |
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US6600953B2 (en) | 2000-12-11 | 2003-07-29 | Impulse Dynamics N.V. | Acute and chronic electrical signal therapy for obesity |
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WO2003042662A2 (en) * | 2001-11-12 | 2003-05-22 | Andre Johan Nel | Determining progesterone cycles in livestock |
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US8150519B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods and apparatus for bilateral renal neuromodulation |
US9308043B2 (en) | 2002-04-08 | 2016-04-12 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
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