US7694828B2 - Method and apparatus for producing autologous clotting components - Google Patents
Method and apparatus for producing autologous clotting components Download PDFInfo
- Publication number
- US7694828B2 US7694828B2 US11/116,153 US11615305A US7694828B2 US 7694828 B2 US7694828 B2 US 7694828B2 US 11615305 A US11615305 A US 11615305A US 7694828 B2 US7694828 B2 US 7694828B2
- Authority
- US
- United States
- Prior art keywords
- piston
- container
- component material
- operable
- tube
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related, expires
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
- B01D17/02—Separation of non-miscible liquids
- B01D17/0202—Separation of non-miscible liquids by ab- or adsorption
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
- B01D17/02—Separation of non-miscible liquids
- B01D17/0217—Separation of non-miscible liquids by centrifugal force
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
- B01D17/08—Thickening liquid suspensions by filtration
- B01D17/10—Thickening liquid suspensions by filtration with stationary filtering elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
- B01J20/04—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising compounds of alkali metals, alkaline earth metals or magnesium
- B01J20/046—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising compounds of alkali metals, alkaline earth metals or magnesium containing halogens, e.g. halides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
- B01J20/10—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
- B01J20/26—Synthetic macromolecular compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
- B01J20/26—Synthetic macromolecular compounds
- B01J20/261—Synthetic macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
- B01J20/26—Synthetic macromolecular compounds
- B01J20/262—Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0427—Platelets; Thrombocytes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/40—Aspects relating to the composition of sorbent or filter aid materials
- B01J2220/46—Materials comprising a mixture of inorganic and organic materials
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- External Artificial Organs (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
Claims (33)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/116,153 US7694828B2 (en) | 2005-04-27 | 2005-04-27 | Method and apparatus for producing autologous clotting components |
EP06252170.3A EP1716901B1 (en) | 2005-04-27 | 2006-04-21 | Separation apparatus and method for separating components from whole blood |
JP2006123728A JP5183883B2 (en) | 2005-04-27 | 2006-04-27 | Method and apparatus for generating an autologous coagulation component |
US12/757,492 US8551344B2 (en) | 2005-04-27 | 2010-04-09 | Method and apparatus for producing autologous clotting components |
US14/047,363 US9011687B2 (en) | 2005-04-27 | 2013-10-07 | Method and apparatus for producing autologous clotting components |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/116,153 US7694828B2 (en) | 2005-04-27 | 2005-04-27 | Method and apparatus for producing autologous clotting components |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/757,492 Division US8551344B2 (en) | 2005-04-27 | 2010-04-09 | Method and apparatus for producing autologous clotting components |
Publications (2)
Publication Number | Publication Date |
---|---|
US20060243676A1 US20060243676A1 (en) | 2006-11-02 |
US7694828B2 true US7694828B2 (en) | 2010-04-13 |
Family
ID=36821537
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/116,153 Expired - Fee Related US7694828B2 (en) | 2005-04-27 | 2005-04-27 | Method and apparatus for producing autologous clotting components |
US12/757,492 Expired - Fee Related US8551344B2 (en) | 2005-04-27 | 2010-04-09 | Method and apparatus for producing autologous clotting components |
US14/047,363 Active US9011687B2 (en) | 2005-04-27 | 2013-10-07 | Method and apparatus for producing autologous clotting components |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/757,492 Expired - Fee Related US8551344B2 (en) | 2005-04-27 | 2010-04-09 | Method and apparatus for producing autologous clotting components |
US14/047,363 Active US9011687B2 (en) | 2005-04-27 | 2013-10-07 | Method and apparatus for producing autologous clotting components |
Country Status (3)
Country | Link |
---|---|
US (3) | US7694828B2 (en) |
EP (1) | EP1716901B1 (en) |
JP (1) | JP5183883B2 (en) |
Cited By (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100226909A1 (en) * | 2009-03-06 | 2010-09-09 | Biomet Biologics, Llc | Method And Apparatus For Producing Autologous Thrombin |
US8162887B2 (en) | 2004-06-23 | 2012-04-24 | Abbott Biotechnology Ltd. | Automatic injection devices |
EP2520316A2 (en) | 2011-05-02 | 2012-11-07 | Biomet Biologics, LLC | Thrombin isolated from blood and blood fractions |
US8317672B2 (en) | 2010-11-19 | 2012-11-27 | Kensey Nash Corporation | Centrifuge method and apparatus |
US8337711B2 (en) | 2008-02-29 | 2012-12-25 | Biomet Biologics, Llc | System and process for separating a material |
US8394006B2 (en) | 2010-11-19 | 2013-03-12 | Kensey Nash Corporation | Centrifuge |
US8469871B2 (en) | 2010-11-19 | 2013-06-25 | Kensey Nash Corporation | Centrifuge |
US8556794B2 (en) | 2010-11-19 | 2013-10-15 | Kensey Nash Corporation | Centrifuge |
US8586324B2 (en) * | 2011-08-15 | 2013-11-19 | Biomet Biologics, Llc | Method and apparatus to create autologous clotting serum |
US8636704B2 (en) | 2009-04-29 | 2014-01-28 | Abbvie Biotechnology Ltd | Automatic injection device |
US8679061B2 (en) * | 2006-06-30 | 2014-03-25 | Abbvie Biotechnology Ltd | Automatic injection device |
US8696905B2 (en) | 2004-02-23 | 2014-04-15 | Circle Biologics, Inc. | Fluid concentrator |
US8708968B2 (en) | 2011-01-24 | 2014-04-29 | Abbvie Biotechnology Ltd. | Removal of needle shields from syringes and automatic injection devices |
US8758301B2 (en) | 2009-12-15 | 2014-06-24 | Abbvie Biotechnology Ltd | Firing button for automatic injection device |
US8808551B2 (en) | 2002-05-24 | 2014-08-19 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
WO2014144505A2 (en) | 2013-03-15 | 2014-09-18 | Biomet Biologics, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
WO2014149300A1 (en) | 2013-03-15 | 2014-09-25 | Biomet Biologics, Llc | Treatment of inflammatory respiratory disease using biological solutions |
WO2014149270A1 (en) | 2013-03-15 | 2014-09-25 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
WO2014149979A1 (en) | 2013-03-15 | 2014-09-25 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
WO2014149301A1 (en) | 2013-03-15 | 2014-09-25 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
US8870733B2 (en) | 2010-11-19 | 2014-10-28 | Kensey Nash Corporation | Centrifuge |
US20140364296A1 (en) * | 2012-01-31 | 2014-12-11 | Argos Therapeutics, Inc. | Centrifuge vessels suitable for live cell processing and associated systems and methods |
US8950586B2 (en) | 2002-05-03 | 2015-02-10 | Hanuman Llc | Methods and apparatus for isolating platelets from blood |
US8992862B2 (en) | 2009-04-03 | 2015-03-31 | Biomet Biologics, Llc | All-in-one means of separating blood components |
US9011684B2 (en) | 2011-03-07 | 2015-04-21 | Spinesmith Holdings, Llc | Fluid concentrator with removable cartridge |
US9011800B2 (en) | 2009-07-16 | 2015-04-21 | Biomet Biologics, Llc | Method and apparatus for separating biological materials |
US9011687B2 (en) | 2005-04-27 | 2015-04-21 | Biomet Biologics, Llc | Method and apparatus for producing autologous clotting components |
WO2015081253A1 (en) | 2013-11-26 | 2015-06-04 | Biomet Biologics, Llc | Methods of mediating macrophage phenotypes |
US9114334B2 (en) | 2002-05-24 | 2015-08-25 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US9120095B2 (en) | 2012-03-29 | 2015-09-01 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating a component of a fluid |
US9138664B2 (en) | 2007-04-12 | 2015-09-22 | Biomet Biologics, Llc | Buoy fractionation system |
US9180244B2 (en) | 2010-04-21 | 2015-11-10 | Abbvie Biotechnology Ltd | Wearable automatic injection device for controlled delivery of therapeutic agents |
US9239276B2 (en) | 2011-04-19 | 2016-01-19 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US9265887B2 (en) | 2011-01-24 | 2016-02-23 | Abbvie Biotechnology Ltd. | Automatic injection devices having overmolded gripping surfaces |
US9308224B2 (en) | 2008-02-27 | 2016-04-12 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
US20160230214A1 (en) * | 2012-04-30 | 2016-08-11 | Life Technologies Corporation | Centrifuge and method for loading a device |
US9480730B2 (en) | 2012-09-25 | 2016-11-01 | Stem Cell Partners Llc | Method and apparatus for preparing single donor thrombin serum |
US9533090B2 (en) | 2010-04-12 | 2017-01-03 | Biomet Biologics, Llc | Method and apparatus for separating a material |
US9550028B2 (en) | 2014-05-06 | 2017-01-24 | Biomet Biologics, LLC. | Single step desiccating bead-in-syringe concentrating device |
US9642956B2 (en) | 2012-08-27 | 2017-05-09 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US9649579B2 (en) | 2007-04-12 | 2017-05-16 | Hanuman Llc | Buoy suspension fractionation system |
US9701728B2 (en) | 2008-02-27 | 2017-07-11 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
US9713810B2 (en) | 2015-03-30 | 2017-07-25 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
US9758806B2 (en) | 2013-03-15 | 2017-09-12 | Biomet Biologics, Llc | Acellular compositions for treating inflammatory disorders |
US9757721B2 (en) | 2015-05-11 | 2017-09-12 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
US9763875B2 (en) | 2009-08-27 | 2017-09-19 | Biomet Biologics, Llc | Implantable device for production of interleukin-1 receptor antagonist |
US9897589B2 (en) | 2002-05-24 | 2018-02-20 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US10125345B2 (en) | 2014-01-31 | 2018-11-13 | Dsm Ip Assets, B.V. | Adipose tissue centrifuge and method of use |
USD838863S1 (en) * | 2015-04-07 | 2019-01-22 | Nissan Chemical Industries, Ltd. | Liquid mixing container |
US10441635B2 (en) | 2014-11-10 | 2019-10-15 | Biomet Biologics, Llc | Methods of treating pain using protein solutions |
US10576130B2 (en) | 2013-03-15 | 2020-03-03 | Biomet Manufacturing, Llc | Treatment of collagen defects using protein solutions |
US10729552B2 (en) | 2015-03-18 | 2020-08-04 | Biomet C.V. | Implant configured for hammertoe and small bone fixation |
US10806867B2 (en) | 2011-01-24 | 2020-10-20 | E3D Agricultural Cooperative Association Ltd. | Injector |
US10960114B2 (en) * | 2015-10-14 | 2021-03-30 | Mario GOISIS | Fat filtration device |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7992725B2 (en) * | 2002-05-03 | 2011-08-09 | Biomet Biologics, Llc | Buoy suspension fractionation system |
AU2003249642A1 (en) | 2002-05-24 | 2003-12-12 | Biomet Manufacturing Corp. | Apparatus and method for separating and concentrating fluids containing multiple components |
DK1848473T3 (en) | 2005-02-07 | 2013-09-02 | Hanuman Llc | Plasma concentrations device |
ES2426941T3 (en) | 2005-02-07 | 2013-10-25 | Hanuman Llc | Apparatus and procedure of platelet rich plasma concentrates |
US7866485B2 (en) * | 2005-02-07 | 2011-01-11 | Hanuman, Llc | Apparatus and method for preparing platelet rich plasma and concentrates thereof |
EP1848474B1 (en) | 2005-02-07 | 2013-06-12 | Hanuman LLC | Platelet rich plasma concentrate apparatus and method |
US8034014B2 (en) | 2007-03-06 | 2011-10-11 | Biomet Biologics, Llc | Angiogenesis initation and growth |
US7901344B2 (en) * | 2007-05-11 | 2011-03-08 | Biomet Biologics, Llc | Methods of reducing surgical complications in cancer patients |
US8012077B2 (en) | 2008-05-23 | 2011-09-06 | Biomet Biologics, Llc | Blood separating device |
WO2010061866A2 (en) * | 2008-11-28 | 2010-06-03 | Terumo Kabushiki Kaisha | Blood bag system and cassette |
US20110238029A1 (en) * | 2008-11-28 | 2011-09-29 | Terumo Kabushiki Kaisha | Blood bag system and cassette |
KR101609226B1 (en) | 2008-12-04 | 2016-04-06 | ģØėŖØģ ėģģ¤ ģ½ķ¬ė ģ“ģ | Apparatus and method for separating and isolating components of a biological fluid |
US8708944B2 (en) * | 2009-02-26 | 2014-04-29 | Javin C. Pierce | System for harvesting and dispensing a fibrin clot |
US8679076B2 (en) * | 2009-02-26 | 2014-03-25 | Javin C. Pierce | Method and apparatus for harvesting and dispensing a fibrin clot |
US20100228175A1 (en) * | 2009-02-26 | 2010-09-09 | Pierce Javin C | System for harvesting and dispensing blood clot |
US20110052561A1 (en) * | 2009-08-27 | 2011-03-03 | Biomet Biologics,LLC | Osteolysis treatment |
US7927563B1 (en) * | 2009-10-13 | 2011-04-19 | Cytomedix, Inc. | Kit for separation of biological fluids |
EP2611456A2 (en) | 2010-09-03 | 2013-07-10 | Biomet Biologics, LLC | Methods and compositions for delivering interleukin-1 receptor antagonist |
US10799871B1 (en) * | 2015-04-29 | 2020-10-13 | John L. Sternick | Aspiration adapter and system |
CA3013659C (en) | 2016-03-10 | 2023-11-14 | Arthrex, Inc. | Systems and methods for preparing protein enhanced serums |
AU2017230806B2 (en) | 2016-03-10 | 2021-06-24 | Arthrex, Inc. | Systems and methods for preparing a thrombin serum |
IL247786B (en) | 2016-09-12 | 2019-08-29 | Plotkin Alexander | Wound covering with haemostatic action and the method of its creation |
EP3512577A1 (en) | 2016-09-16 | 2019-07-24 | Fenwal, Inc. | Blood separation systems and methods employing centrifugal and spinning membrane separation techniques |
KR101710844B1 (en) * | 2016-11-25 | 2017-02-27 | ģ¬ģė | Impeller for preventing blood coagulation and blood transfusion set including the same |
EP3705146A3 (en) | 2019-03-05 | 2020-11-25 | Fenwal, Inc. | Collection of mononuclear cells and peripheral blood stem cells |
EP4238595A3 (en) | 2019-05-23 | 2023-11-29 | Fenwal, Inc. | Adjustment of target interface location between separated fluid components in a centrifuge |
US11890399B2 (en) | 2019-05-23 | 2024-02-06 | Fenwal, Inc. | Centrifugal separation and collection of red blood cells, plasma, or both red blood cells and plasma |
US11957828B2 (en) | 2019-09-16 | 2024-04-16 | Fenwal, Inc. | Dynamic adjustment of algorithms for separation and collection of blood components |
US11633530B2 (en) * | 2021-08-03 | 2023-04-25 | Dcstar Inc | Suction device for sucking obstruction in respiratory tract and use method therefor |
Citations (109)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3723244A (en) | 1971-01-18 | 1973-03-27 | Atomic Energy Commission | Fibrous fibrin sheet and method for producing same |
US3850369A (en) | 1973-03-08 | 1974-11-26 | Coulter Electronics | Centrifuge for preparing platelet rich plasma |
US3897343A (en) | 1974-02-27 | 1975-07-29 | Becton Dickinson Co | Plasma separator-hydrostatic pressure type |
US3909419A (en) | 1974-02-27 | 1975-09-30 | Becton Dickinson Co | Plasma separator with squeezed sealant |
US3931010A (en) | 1974-02-27 | 1976-01-06 | Becton, Dickinson And Company | Serum/plasma separators with centrifugal valves |
US3931018A (en) | 1974-08-09 | 1976-01-06 | Becton, Dickinson And Company | Assembly for collection, separation and filtration of blood |
US3982691A (en) | 1974-10-09 | 1976-09-28 | Schlutz Charles A | Centrifuge separation and washing device and method |
US4046699A (en) | 1976-11-01 | 1977-09-06 | Corning Glass Works | Access device for centrifugal separation assemblies |
US4055501A (en) | 1976-01-16 | 1977-10-25 | Sherwood Medical Industries Inc. | Fluid collection device with phase partitioning means |
US4077396A (en) | 1976-04-02 | 1978-03-07 | Wardlaw Stephen C | Material layer volume determination |
US4154690A (en) | 1977-03-16 | 1979-05-15 | Uwe Ballies | Device for use in the centrifugal separation of components of a liquid |
US4187979A (en) | 1978-09-21 | 1980-02-12 | Baxter Travenol Laboratories, Inc. | Method and system for fractionating a quantity of blood into the components thereof |
US4322298A (en) | 1981-06-01 | 1982-03-30 | Advanced Blood Component Technology, Inc. | Centrifugal cell separator, and method of use thereof |
US4379849A (en) | 1979-10-04 | 1983-04-12 | Ken Heimreid | Method and means for the examination of uncoagulated blood |
US4416654A (en) | 1981-09-03 | 1983-11-22 | Haemonetics Corporation | Pheresis apparatus |
US4464167A (en) | 1981-09-03 | 1984-08-07 | Haemonetics Corporation | Pheresis apparatus |
US4675117A (en) | 1984-03-21 | 1987-06-23 | Fresenius Ag | Method of separating blood and apparatus for carrying out the method |
US4714457A (en) | 1986-09-15 | 1987-12-22 | Robert Alterbaum | Method and apparatus for use in preparation of fibrinogen from a patient's blood |
US4776964A (en) | 1984-08-24 | 1988-10-11 | William F. McLaughlin | Closed hemapheresis system and method |
US4818386A (en) | 1987-10-08 | 1989-04-04 | Becton, Dickinson And Company | Device for separating the components of a liquid sample having higher and lower specific gravities |
US5019243A (en) | 1987-04-03 | 1991-05-28 | Mcewen James A | Apparatus for collecting blood |
US5053127A (en) | 1987-01-13 | 1991-10-01 | William F. McLaughlin | Continuous centrifugation system and method for directly deriving intermediate density material from a suspension |
EP0244834B1 (en) | 1986-05-09 | 1992-03-18 | BEHRINGWERKE Aktiengesellschaft | Process for producing a factor v concentrate |
US5131907A (en) | 1986-04-04 | 1992-07-21 | Thomas Jefferson University | Method of treating a synthetic naturally occurring surface with a collagen laminate to support microvascular endothelial cell growth, and the surface itself |
US5141645A (en) | 1986-01-24 | 1992-08-25 | Terumo Corporation | Apparatus for separation of blood components |
US5147290A (en) | 1986-04-24 | 1992-09-15 | Stafilum Ab | Method and machine based on the principle of centrifugation for cytapheresis such as platelet apheresis, and for plasma exchange treatment |
US5165938A (en) | 1984-11-29 | 1992-11-24 | Regents Of The University Of Minnesota | Wound healing agents derived from platelets |
US5171456A (en) | 1990-06-14 | 1992-12-15 | Baxter International Inc. | Automated blood component separation procedure and apparatus promoting different functional characteristics in multiple blood components |
US5185001A (en) | 1990-01-18 | 1993-02-09 | The Research Foundation Of State University Of New York | Method of preparing autologous plasma fibrin and application apparatus therefor |
US5234608A (en) | 1990-12-11 | 1993-08-10 | Baxter International Inc. | Systems and methods for processing cellular rich suspensions |
US5269927A (en) | 1991-05-29 | 1993-12-14 | Sherwood Medical Company | Separation device for use in blood collection tubes |
US5271852A (en) | 1992-05-01 | 1993-12-21 | E. I. Du Pont De Nemours And Company | Centrifugal methods using a phase-separation tube |
US5318782A (en) | 1986-10-03 | 1994-06-07 | Weis Fogh Ulla S | Method for preparing tissue repair promoting substances |
US5322620A (en) | 1987-01-30 | 1994-06-21 | Baxter International Inc. | Centrifugation system having an interface detection surface |
US5344752A (en) | 1991-10-30 | 1994-09-06 | Thomas Jefferson University | Plasma-based platelet concentrate preparations |
US5370802A (en) | 1987-01-30 | 1994-12-06 | Baxter International Inc. | Enhanced yield platelet collection systems and methods |
US5376263A (en) | 1982-12-13 | 1994-12-27 | William F. McLaughlin | Pump control apparatus for cellular filtration systems employing rotating microporous membranes |
US5387187A (en) | 1992-12-01 | 1995-02-07 | Haemonetics Corporation | Red cell apheresis method |
US5403272A (en) | 1992-05-29 | 1995-04-04 | Baxter International Inc. | Apparatus and methods for generating leukocyte free platelet concentrate |
US5456885A (en) | 1993-07-12 | 1995-10-10 | Coleman; Charles M. | Fluid collection, separation and dispensing tube |
US5494592A (en) | 1993-04-27 | 1996-02-27 | Haemonetics Corporation | Apheresis apparatus and method |
US5501371A (en) | 1994-07-07 | 1996-03-26 | Schwartz-Feldman; Jean | Mixing syringe |
US5560830A (en) | 1994-12-13 | 1996-10-01 | Coleman; Charles M. | Separator float and tubular body for blood collection and separation and method of use thereof |
US5585007A (en) | 1994-12-07 | 1996-12-17 | Plasmaseal Corporation | Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant |
US5601727A (en) | 1991-11-04 | 1997-02-11 | Pall Corporation | Device and method for separating plasma from a biological fluid |
US5614106A (en) | 1993-03-12 | 1997-03-25 | Baxter International Inc. | Method and apparatus for collection of platelets |
US5632895A (en) | 1993-08-13 | 1997-05-27 | Nigata Engineering Co., Ltd. | Serum separating device and apparatus for serum separation |
US5632905A (en) | 1995-08-07 | 1997-05-27 | Haynes; John L. | Method and apparatus for separating formed and unformed components |
US5707876A (en) | 1996-03-25 | 1998-01-13 | Stephen C. Wardlaw | Method and apparatus for harvesting constituent layers from a centrifuged material mixture |
US5707331A (en) | 1995-05-05 | 1998-01-13 | John R. Wells | Automatic multiple-decanting centrifuge |
US5733466A (en) | 1996-02-06 | 1998-03-31 | International Business Machines Corporation | Electrolytic method of depositing gold connectors on a printed circuit board |
US5733545A (en) | 1995-03-03 | 1998-03-31 | Quantic Biomedical Partners | Platelet glue wound sealant |
US5795571A (en) | 1992-06-24 | 1998-08-18 | Bristol-Myers Squibb Company | Composition containing autologous thrombin blood fraction for use in a medical procedure |
US5817519A (en) | 1995-12-28 | 1998-10-06 | Bayer Corporation | Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples |
US5833866A (en) | 1991-12-23 | 1998-11-10 | Baxter International Inc. | Blood collection systems and methods which derive instantaneous blood component yield information during blood processing |
US5834418A (en) | 1996-03-20 | 1998-11-10 | Theratechnologies, Inc. | Process for the preparation of platelet growth factors extract |
US5837150A (en) | 1995-06-07 | 1998-11-17 | Cobe Laboratories, Inc. | Extracorporeal blood processing methods |
US5863892A (en) | 1992-02-26 | 1999-01-26 | Allergan Inc. | Use of platelet derived growth factor in ophthalmic wound healing |
US5865785A (en) | 1996-02-23 | 1999-02-02 | Baxter International Inc. | Systems and methods for on line finishing of cellular blood products like platelets harvested for therapeutic purposes |
US5900245A (en) | 1996-03-22 | 1999-05-04 | Focal, Inc. | Compliant tissue sealants |
US5899874A (en) | 1992-04-30 | 1999-05-04 | Stiftelsen For Medicinsk-Teknisk Utveckling | Preparation and method for production of platelet concentrates with significantly prolonged viabilty during storage |
US5934803A (en) | 1997-10-30 | 1999-08-10 | Physical Systems, Inc. | Apparatus and method for mixing multi-part reaction materials under vacuum |
US5938621A (en) | 1997-09-12 | 1999-08-17 | Becton Dickinson And Company | Collection container assembly |
US5955436A (en) | 1990-11-20 | 1999-09-21 | Alcon Laboratories, Inc. | Use of platelet derived growth factor to enhance wound healing |
US5955032A (en) | 1997-09-12 | 1999-09-21 | Becton Dickinson And Company | Collection container assembly |
US5958253A (en) | 1994-12-02 | 1999-09-28 | Bristol-Myers Squibb Company | Centrifuge reagent delivery method |
US5958250A (en) | 1995-06-07 | 1999-09-28 | Baxter International Inc. | Blood processing systems and methods which optically derive the volume of platelets contained in a plasma constituent |
US5980734A (en) | 1996-05-09 | 1999-11-09 | Itoh; Teruaki | Auxiliary apparatus for sampling blood serum |
US6010627A (en) | 1995-06-06 | 2000-01-04 | Quantic Biomedical Partners | Device for concentrating plasma |
US6022306A (en) | 1995-04-18 | 2000-02-08 | Cobe Laboratories, Inc. | Method and apparatus for collecting hyperconcentrated platelets |
US6025201A (en) | 1995-12-28 | 2000-02-15 | Bayer Corporation | Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples |
US6027655A (en) | 1993-11-19 | 2000-02-22 | Bristol-Myers Squibb Company | Apparatus and method for centrifugally separating blood and then forming a fibrin monomer |
US6051146A (en) | 1998-01-20 | 2000-04-18 | Cobe Laboratories, Inc. | Methods for separation of particles |
US6054122A (en) | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
US6053856A (en) | 1995-04-18 | 2000-04-25 | Cobe Laboratories | Tubing set apparatus and method for separation of fluid components |
US6063624A (en) | 1997-06-09 | 2000-05-16 | Baxter International Inc. | Platelet suspensions and methods for resuspending platelets |
US6071422A (en) | 1995-04-18 | 2000-06-06 | Cobe Laboratories, Inc. | Particle separation method and apparatus |
US6071421A (en) | 1991-12-23 | 2000-06-06 | Baxter International Inc. | Systems and methods for obtaining a platelet suspension having a reduced number of leukocytes |
US6090793A (en) | 1992-02-12 | 2000-07-18 | Monsanto Europe S.A. | Non-mitogenic substance, its preparation and use |
US6096309A (en) | 1997-06-18 | 2000-08-01 | Cohesion Technologies, Inc. | Compositions containing thrombin and microfibrillar nanometer collagen, and methods for preparation and use thereof |
US6117425A (en) | 1990-11-27 | 2000-09-12 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, method of their production and use |
EP1079224A2 (en) | 1999-08-20 | 2001-02-28 | Wardlaw, Stephen Clark | Method and assembly for separating formed constituents from a liquid constituent in a complex biologic fluid sample |
US6197325B1 (en) | 1990-11-27 | 2001-03-06 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
US6196987B1 (en) | 1995-06-07 | 2001-03-06 | Gambro, Inc. | Extracorporeal blood processing methods and apparatus |
US6200287B1 (en) | 1997-09-05 | 2001-03-13 | Gambro, Inc. | Extracorporeal blood processing methods and apparatus |
US6245900B1 (en) | 1994-02-23 | 2001-06-12 | Kyowa Hakko Kogyo Co., Ltd. | Platelet production promoting agent |
US6274090B1 (en) | 1998-08-05 | 2001-08-14 | Thermogenesis Corp. | Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby |
US6280400B1 (en) | 1998-12-05 | 2001-08-28 | Becton Dickinson And Company | Device and method for separating component of a liquid sample |
US6296602B1 (en) | 1999-03-17 | 2001-10-02 | Transfusion Technologies Corporation | Method for collecting platelets and other blood components from whole blood |
US6368298B1 (en) | 1997-06-24 | 2002-04-09 | Roberto Beretta | Preparing autologous fibrin glue |
US6417004B1 (en) | 1999-04-29 | 2002-07-09 | Helena Laboratories Corporation | Enhancing clot detection in activated clotting time and other fibrin endpoint based tests |
US20020090711A1 (en) | 2000-11-20 | 2002-07-11 | Goran Karlsson | Process for preparing latent antithrombin III |
WO2002060925A1 (en) | 2001-01-30 | 2002-08-08 | Genzymes Corporation | Method of producing latent antithrombin iii |
US20020114775A1 (en) | 1996-09-23 | 2002-08-22 | Incept Llc | Crosslinking agents and methods of use |
US6444228B1 (en) | 1996-04-30 | 2002-09-03 | Medtronic, Inc. | Autologous fibrin sealant and method for making the same |
US6472162B1 (en) | 1999-06-04 | 2002-10-29 | Thermogenesis Corp. | Method for preparing thrombin for use in a biological glue |
US20020169408A1 (en) | 1997-06-24 | 2002-11-14 | Roberto Beretta | Systems and methods for preparing autologous fibrin glue |
US20020172666A1 (en) | 1999-12-14 | 2002-11-21 | Sacchi Maria Cristina | Process for preparing an autologous platelet gel and membrane thereof, and a kit for carrying out this process |
US6516953B1 (en) | 1998-12-05 | 2003-02-11 | Becton, Dickinson And Company | Device for separating components of a fluid sample |
US6596180B2 (en) | 1996-04-30 | 2003-07-22 | Medtronic, Inc. | System and method for the production of autologous platelet gel |
US20030198687A1 (en) * | 2002-04-18 | 2003-10-23 | Keith Bennett, M.D. | Wound care composition |
WO2003099412A1 (en) | 2002-05-24 | 2003-12-04 | Biomet Manufacturing Corp. | Apparatus and method for separating and concentrating fluids containing multiple components |
WO2004009207A1 (en) | 2002-07-18 | 2004-01-29 | Hanuman Llc | Plasma concentrating apparatus and method |
US6733471B1 (en) | 1998-03-16 | 2004-05-11 | Medtronic, Inc. | Hemostatic system and components for extracorporeal circuit |
US20040120942A1 (en) | 2002-12-23 | 2004-06-24 | Mcginnis Daniel | Device and process for the preparation of autologous thrombin serum |
US20040182795A1 (en) | 2003-03-21 | 2004-09-23 | Randel Dorian | Apparatus and method for concentration of plasma from whole blood |
US20050109716A1 (en) | 2002-05-24 | 2005-05-26 | Michael Leach | Apparatus and method for separating and concentrating fluids containing multiple components |
US6905612B2 (en) | 2003-03-21 | 2005-06-14 | Hanuman Llc | Plasma concentrate apparatus and method |
US7553413B2 (en) | 2005-02-07 | 2009-06-30 | Hanuman Llc | Plasma concentrator device |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4846800A (en) * | 1987-10-14 | 1989-07-11 | Kenneth Ouriel | Two chambered autotransfuser device and method of use |
DK119490D0 (en) * | 1990-05-14 | 1990-05-14 | Unes As | Apparatus for the preparation of a concentrate of coagulation factors, such as the fibrinogen, from a blood portion |
US5344458A (en) | 1992-08-06 | 1994-09-06 | Bonutti Peter M | Arthroplasty component |
US5795751A (en) | 1994-06-09 | 1998-08-18 | Lockheed Martin Idaho Technologies Company | Biofilter for removal of nitrogen oxides from contaminated gases under aerobic conditions |
US6123655A (en) * | 1996-04-24 | 2000-09-26 | Fell; Claude | Cell separation system with variable size chamber for the processing of biological fluids |
WO1998030331A1 (en) * | 1997-01-08 | 1998-07-16 | Bristol-Myers Squibb Company | Centrifuge apparatus for separating blood |
AU770634B2 (en) | 1998-06-23 | 2004-02-26 | Shanbrom Technologies, Llc | Method and apparatus for the production of purified plasma proteins |
DE19916430C1 (en) * | 1999-04-12 | 2001-01-18 | Inst Chemo Biosensorik | Apparatus for use in performing receptor ligand and affinity tests |
BR0115188A (en) | 2000-11-08 | 2004-02-03 | Octopharma Ag | Process for the preparation of latent antithrombin iii |
JP2004536794A (en) * | 2001-04-09 | 2004-12-09 | ć”ććććććÆćć¤ć³ć³ć¼ćć¬ć¤ććć | Method for separating blood components using microcentrifuge and method for using the same |
US20030205538A1 (en) * | 2002-05-03 | 2003-11-06 | Randel Dorian | Methods and apparatus for isolating platelets from blood |
WO2004104553A2 (en) * | 2003-05-19 | 2004-12-02 | Harvest Technologies Corporation | Method and apparatus for separating fluid components |
US7422905B2 (en) * | 2004-02-27 | 2008-09-09 | Medtronic, Inc. | Blood coagulation test cartridge, system, and method |
US8157867B2 (en) | 2004-07-09 | 2012-04-17 | Zimmer, Inc. | Trochlear groove implants and related methods and instruments |
US7694828B2 (en) | 2005-04-27 | 2010-04-13 | Biomet Manufacturing Corp. | Method and apparatus for producing autologous clotting components |
-
2005
- 2005-04-27 US US11/116,153 patent/US7694828B2/en not_active Expired - Fee Related
-
2006
- 2006-04-21 EP EP06252170.3A patent/EP1716901B1/en not_active Not-in-force
- 2006-04-27 JP JP2006123728A patent/JP5183883B2/en not_active Expired - Fee Related
-
2010
- 2010-04-09 US US12/757,492 patent/US8551344B2/en not_active Expired - Fee Related
-
2013
- 2013-10-07 US US14/047,363 patent/US9011687B2/en active Active
Patent Citations (120)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3723244A (en) | 1971-01-18 | 1973-03-27 | Atomic Energy Commission | Fibrous fibrin sheet and method for producing same |
US3850369A (en) | 1973-03-08 | 1974-11-26 | Coulter Electronics | Centrifuge for preparing platelet rich plasma |
US3897343A (en) | 1974-02-27 | 1975-07-29 | Becton Dickinson Co | Plasma separator-hydrostatic pressure type |
US3909419A (en) | 1974-02-27 | 1975-09-30 | Becton Dickinson Co | Plasma separator with squeezed sealant |
US3931010A (en) | 1974-02-27 | 1976-01-06 | Becton, Dickinson And Company | Serum/plasma separators with centrifugal valves |
US3931018A (en) | 1974-08-09 | 1976-01-06 | Becton, Dickinson And Company | Assembly for collection, separation and filtration of blood |
US3982691A (en) | 1974-10-09 | 1976-09-28 | Schlutz Charles A | Centrifuge separation and washing device and method |
US4055501A (en) | 1976-01-16 | 1977-10-25 | Sherwood Medical Industries Inc. | Fluid collection device with phase partitioning means |
US4077396A (en) | 1976-04-02 | 1978-03-07 | Wardlaw Stephen C | Material layer volume determination |
US4046699A (en) | 1976-11-01 | 1977-09-06 | Corning Glass Works | Access device for centrifugal separation assemblies |
US4154690A (en) | 1977-03-16 | 1979-05-15 | Uwe Ballies | Device for use in the centrifugal separation of components of a liquid |
US4187979A (en) | 1978-09-21 | 1980-02-12 | Baxter Travenol Laboratories, Inc. | Method and system for fractionating a quantity of blood into the components thereof |
US4379849A (en) | 1979-10-04 | 1983-04-12 | Ken Heimreid | Method and means for the examination of uncoagulated blood |
US4322298A (en) | 1981-06-01 | 1982-03-30 | Advanced Blood Component Technology, Inc. | Centrifugal cell separator, and method of use thereof |
US4416654A (en) | 1981-09-03 | 1983-11-22 | Haemonetics Corporation | Pheresis apparatus |
US4464167A (en) | 1981-09-03 | 1984-08-07 | Haemonetics Corporation | Pheresis apparatus |
US5376263A (en) | 1982-12-13 | 1994-12-27 | William F. McLaughlin | Pump control apparatus for cellular filtration systems employing rotating microporous membranes |
US4675117A (en) | 1984-03-21 | 1987-06-23 | Fresenius Ag | Method of separating blood and apparatus for carrying out the method |
US4776964A (en) | 1984-08-24 | 1988-10-11 | William F. McLaughlin | Closed hemapheresis system and method |
US5165938A (en) | 1984-11-29 | 1992-11-24 | Regents Of The University Of Minnesota | Wound healing agents derived from platelets |
US5141645A (en) | 1986-01-24 | 1992-08-25 | Terumo Corporation | Apparatus for separation of blood components |
US5131907A (en) | 1986-04-04 | 1992-07-21 | Thomas Jefferson University | Method of treating a synthetic naturally occurring surface with a collagen laminate to support microvascular endothelial cell growth, and the surface itself |
US5147290A (en) | 1986-04-24 | 1992-09-15 | Stafilum Ab | Method and machine based on the principle of centrifugation for cytapheresis such as platelet apheresis, and for plasma exchange treatment |
EP0244834B1 (en) | 1986-05-09 | 1992-03-18 | BEHRINGWERKE Aktiengesellschaft | Process for producing a factor v concentrate |
US4714457A (en) | 1986-09-15 | 1987-12-22 | Robert Alterbaum | Method and apparatus for use in preparation of fibrinogen from a patient's blood |
US5318782A (en) | 1986-10-03 | 1994-06-07 | Weis Fogh Ulla S | Method for preparing tissue repair promoting substances |
US5053127A (en) | 1987-01-13 | 1991-10-01 | William F. McLaughlin | Continuous centrifugation system and method for directly deriving intermediate density material from a suspension |
US5370802A (en) | 1987-01-30 | 1994-12-06 | Baxter International Inc. | Enhanced yield platelet collection systems and methods |
US6071423A (en) | 1987-01-30 | 2000-06-06 | Baxter International Inc. | Methods of collecting a blood plasma constituent |
US5494578A (en) | 1987-01-30 | 1996-02-27 | Baxter International Inc. | Centrifugation pheresis system |
US5322620A (en) | 1987-01-30 | 1994-06-21 | Baxter International Inc. | Centrifugation system having an interface detection surface |
US5019243A (en) | 1987-04-03 | 1991-05-28 | Mcewen James A | Apparatus for collecting blood |
US4818386A (en) | 1987-10-08 | 1989-04-04 | Becton, Dickinson And Company | Device for separating the components of a liquid sample having higher and lower specific gravities |
US5185001A (en) | 1990-01-18 | 1993-02-09 | The Research Foundation Of State University Of New York | Method of preparing autologous plasma fibrin and application apparatus therefor |
US5171456A (en) | 1990-06-14 | 1992-12-15 | Baxter International Inc. | Automated blood component separation procedure and apparatus promoting different functional characteristics in multiple blood components |
US5955436A (en) | 1990-11-20 | 1999-09-21 | Alcon Laboratories, Inc. | Use of platelet derived growth factor to enhance wound healing |
US6054122A (en) | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
US6117425A (en) | 1990-11-27 | 2000-09-12 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, method of their production and use |
US6197325B1 (en) | 1990-11-27 | 2001-03-06 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
US5234608A (en) | 1990-12-11 | 1993-08-10 | Baxter International Inc. | Systems and methods for processing cellular rich suspensions |
US5269927A (en) | 1991-05-29 | 1993-12-14 | Sherwood Medical Company | Separation device for use in blood collection tubes |
US5344752A (en) | 1991-10-30 | 1994-09-06 | Thomas Jefferson University | Plasma-based platelet concentrate preparations |
US5601727A (en) | 1991-11-04 | 1997-02-11 | Pall Corporation | Device and method for separating plasma from a biological fluid |
US6071421A (en) | 1991-12-23 | 2000-06-06 | Baxter International Inc. | Systems and methods for obtaining a platelet suspension having a reduced number of leukocytes |
US5833866A (en) | 1991-12-23 | 1998-11-10 | Baxter International Inc. | Blood collection systems and methods which derive instantaneous blood component yield information during blood processing |
US6090793A (en) | 1992-02-12 | 2000-07-18 | Monsanto Europe S.A. | Non-mitogenic substance, its preparation and use |
US5863892A (en) | 1992-02-26 | 1999-01-26 | Allergan Inc. | Use of platelet derived growth factor in ophthalmic wound healing |
US5899874A (en) | 1992-04-30 | 1999-05-04 | Stiftelsen For Medicinsk-Teknisk Utveckling | Preparation and method for production of platelet concentrates with significantly prolonged viabilty during storage |
US5271852A (en) | 1992-05-01 | 1993-12-21 | E. I. Du Pont De Nemours And Company | Centrifugal methods using a phase-separation tube |
US5649903A (en) | 1992-05-29 | 1997-07-22 | Baxter International Inc. | Apparatus and methods for generating leukocyte free platelet concentrate |
US5403272A (en) | 1992-05-29 | 1995-04-04 | Baxter International Inc. | Apparatus and methods for generating leukocyte free platelet concentrate |
US5795571A (en) | 1992-06-24 | 1998-08-18 | Bristol-Myers Squibb Company | Composition containing autologous thrombin blood fraction for use in a medical procedure |
US5387187A (en) | 1992-12-01 | 1995-02-07 | Haemonetics Corporation | Red cell apheresis method |
US5614106A (en) | 1993-03-12 | 1997-03-25 | Baxter International Inc. | Method and apparatus for collection of platelets |
US5494592A (en) | 1993-04-27 | 1996-02-27 | Haemonetics Corporation | Apheresis apparatus and method |
US5607579A (en) | 1993-04-27 | 1997-03-04 | Haemonetics Corporation | Apheresis apparatus for separating an intermediate density component from whole blood |
US5456885A (en) | 1993-07-12 | 1995-10-10 | Coleman; Charles M. | Fluid collection, separation and dispensing tube |
US5632895A (en) | 1993-08-13 | 1997-05-27 | Nigata Engineering Co., Ltd. | Serum separating device and apparatus for serum separation |
US6027655A (en) | 1993-11-19 | 2000-02-22 | Bristol-Myers Squibb Company | Apparatus and method for centrifugally separating blood and then forming a fibrin monomer |
US6245900B1 (en) | 1994-02-23 | 2001-06-12 | Kyowa Hakko Kogyo Co., Ltd. | Platelet production promoting agent |
US5501371A (en) | 1994-07-07 | 1996-03-26 | Schwartz-Feldman; Jean | Mixing syringe |
US5958253A (en) | 1994-12-02 | 1999-09-28 | Bristol-Myers Squibb Company | Centrifuge reagent delivery method |
US5788662A (en) | 1994-12-07 | 1998-08-04 | Plasmaseal Llc | Methods for making concentrated plasma and/or tissue sealant |
US5585007A (en) | 1994-12-07 | 1996-12-17 | Plasmaseal Corporation | Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant |
US6063297A (en) | 1994-12-07 | 2000-05-16 | Plasmaseal Llc | Method and apparatus for making concentrated plasma and/or tissue sealant |
US6214338B1 (en) | 1994-12-07 | 2001-04-10 | Plasmaseal Llc | Plasma concentrate and method of processing blood for same |
US5560830A (en) | 1994-12-13 | 1996-10-01 | Coleman; Charles M. | Separator float and tubular body for blood collection and separation and method of use thereof |
US5733545A (en) | 1995-03-03 | 1998-03-31 | Quantic Biomedical Partners | Platelet glue wound sealant |
US6071422A (en) | 1995-04-18 | 2000-06-06 | Cobe Laboratories, Inc. | Particle separation method and apparatus |
US6053856A (en) | 1995-04-18 | 2000-04-25 | Cobe Laboratories | Tubing set apparatus and method for separation of fluid components |
US6022306A (en) | 1995-04-18 | 2000-02-08 | Cobe Laboratories, Inc. | Method and apparatus for collecting hyperconcentrated platelets |
US5707331A (en) | 1995-05-05 | 1998-01-13 | John R. Wells | Automatic multiple-decanting centrifuge |
US6010627A (en) | 1995-06-06 | 2000-01-04 | Quantic Biomedical Partners | Device for concentrating plasma |
US5837150A (en) | 1995-06-07 | 1998-11-17 | Cobe Laboratories, Inc. | Extracorporeal blood processing methods |
US5958250A (en) | 1995-06-07 | 1999-09-28 | Baxter International Inc. | Blood processing systems and methods which optically derive the volume of platelets contained in a plasma constituent |
US6196987B1 (en) | 1995-06-07 | 2001-03-06 | Gambro, Inc. | Extracorporeal blood processing methods and apparatus |
US5632905A (en) | 1995-08-07 | 1997-05-27 | Haynes; John L. | Method and apparatus for separating formed and unformed components |
US6025201A (en) | 1995-12-28 | 2000-02-15 | Bayer Corporation | Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples |
US5817519A (en) | 1995-12-28 | 1998-10-06 | Bayer Corporation | Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples |
US5733466A (en) | 1996-02-06 | 1998-03-31 | International Business Machines Corporation | Electrolytic method of depositing gold connectors on a printed circuit board |
US6051147A (en) | 1996-02-23 | 2000-04-18 | Baxter International Inc. | Methods for on line finishing of cellular blood products like platelets harvested for therapeutic purposes |
US5865785A (en) | 1996-02-23 | 1999-02-02 | Baxter International Inc. | Systems and methods for on line finishing of cellular blood products like platelets harvested for therapeutic purposes |
US5834418A (en) | 1996-03-20 | 1998-11-10 | Theratechnologies, Inc. | Process for the preparation of platelet growth factors extract |
US5900245A (en) | 1996-03-22 | 1999-05-04 | Focal, Inc. | Compliant tissue sealants |
US5707876A (en) | 1996-03-25 | 1998-01-13 | Stephen C. Wardlaw | Method and apparatus for harvesting constituent layers from a centrifuged material mixture |
US6596180B2 (en) | 1996-04-30 | 2003-07-22 | Medtronic, Inc. | System and method for the production of autologous platelet gel |
US6719901B2 (en) | 1996-04-30 | 2004-04-13 | Medtronic, Inc. | System for the production of an autologous thrombin |
US6444228B1 (en) | 1996-04-30 | 2002-09-03 | Medtronic, Inc. | Autologous fibrin sealant and method for making the same |
US5980734A (en) | 1996-05-09 | 1999-11-09 | Itoh; Teruaki | Auxiliary apparatus for sampling blood serum |
US20020114775A1 (en) | 1996-09-23 | 2002-08-22 | Incept Llc | Crosslinking agents and methods of use |
US6063624A (en) | 1997-06-09 | 2000-05-16 | Baxter International Inc. | Platelet suspensions and methods for resuspending platelets |
US6096309A (en) | 1997-06-18 | 2000-08-01 | Cohesion Technologies, Inc. | Compositions containing thrombin and microfibrillar nanometer collagen, and methods for preparation and use thereof |
US20020169408A1 (en) | 1997-06-24 | 2002-11-14 | Roberto Beretta | Systems and methods for preparing autologous fibrin glue |
US6368298B1 (en) | 1997-06-24 | 2002-04-09 | Roberto Beretta | Preparing autologous fibrin glue |
US6200287B1 (en) | 1997-09-05 | 2001-03-13 | Gambro, Inc. | Extracorporeal blood processing methods and apparatus |
US5938621A (en) | 1997-09-12 | 1999-08-17 | Becton Dickinson And Company | Collection container assembly |
US5955032A (en) | 1997-09-12 | 1999-09-21 | Becton Dickinson And Company | Collection container assembly |
US5934803A (en) | 1997-10-30 | 1999-08-10 | Physical Systems, Inc. | Apparatus and method for mixing multi-part reaction materials under vacuum |
US6051146A (en) | 1998-01-20 | 2000-04-18 | Cobe Laboratories, Inc. | Methods for separation of particles |
US6733471B1 (en) | 1998-03-16 | 2004-05-11 | Medtronic, Inc. | Hemostatic system and components for extracorporeal circuit |
US6274090B1 (en) | 1998-08-05 | 2001-08-14 | Thermogenesis Corp. | Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby |
US6280400B1 (en) | 1998-12-05 | 2001-08-28 | Becton Dickinson And Company | Device and method for separating component of a liquid sample |
US6516953B1 (en) | 1998-12-05 | 2003-02-11 | Becton, Dickinson And Company | Device for separating components of a fluid sample |
US6296602B1 (en) | 1999-03-17 | 2001-10-02 | Transfusion Technologies Corporation | Method for collecting platelets and other blood components from whole blood |
US6417004B1 (en) | 1999-04-29 | 2002-07-09 | Helena Laboratories Corporation | Enhancing clot detection in activated clotting time and other fibrin endpoint based tests |
US6472162B1 (en) | 1999-06-04 | 2002-10-29 | Thermogenesis Corp. | Method for preparing thrombin for use in a biological glue |
EP1079224A2 (en) | 1999-08-20 | 2001-02-28 | Wardlaw, Stephen Clark | Method and assembly for separating formed constituents from a liquid constituent in a complex biologic fluid sample |
US20020172666A1 (en) | 1999-12-14 | 2002-11-21 | Sacchi Maria Cristina | Process for preparing an autologous platelet gel and membrane thereof, and a kit for carrying out this process |
US20020090711A1 (en) | 2000-11-20 | 2002-07-11 | Goran Karlsson | Process for preparing latent antithrombin III |
WO2002060925A1 (en) | 2001-01-30 | 2002-08-08 | Genzymes Corporation | Method of producing latent antithrombin iii |
US20030198687A1 (en) * | 2002-04-18 | 2003-10-23 | Keith Bennett, M.D. | Wound care composition |
WO2003099412A1 (en) | 2002-05-24 | 2003-12-04 | Biomet Manufacturing Corp. | Apparatus and method for separating and concentrating fluids containing multiple components |
US20050109716A1 (en) | 2002-05-24 | 2005-05-26 | Michael Leach | Apparatus and method for separating and concentrating fluids containing multiple components |
US7179391B2 (en) | 2002-05-24 | 2007-02-20 | Biomet Manufacturing Corp. | Apparatus and method for separating and concentrating fluids containing multiple components |
WO2004009207A1 (en) | 2002-07-18 | 2004-01-29 | Hanuman Llc | Plasma concentrating apparatus and method |
US20040120942A1 (en) | 2002-12-23 | 2004-06-24 | Mcginnis Daniel | Device and process for the preparation of autologous thrombin serum |
US20040182795A1 (en) | 2003-03-21 | 2004-09-23 | Randel Dorian | Apparatus and method for concentration of plasma from whole blood |
US6905612B2 (en) | 2003-03-21 | 2005-06-14 | Hanuman Llc | Plasma concentrate apparatus and method |
US7553413B2 (en) | 2005-02-07 | 2009-06-30 | Hanuman Llc | Plasma concentrator device |
US20090236297A1 (en) | 2005-02-07 | 2009-09-24 | Hanuman, Llc | Plasma Concentrator Device |
Non-Patent Citations (3)
Title |
---|
Fibrostik(TM) Plasma Concentrator, Attention Operating Surgeon, Cell Factor Technologies, Inc., Jul. 2003. |
Fibrostikā¢ Plasma Concentrator, Attention Operating Surgeon, Cell Factor Technologies, Inc., Jul. 2003. |
International Search Report for PCT/US2006/003598 mailed Jan. 6, 2006 claiming benefit of U.S. Appl. No. 60/640,860 filed Feb. 7, 2005. |
Cited By (101)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8950586B2 (en) | 2002-05-03 | 2015-02-10 | Hanuman Llc | Methods and apparatus for isolating platelets from blood |
US9114334B2 (en) | 2002-05-24 | 2015-08-25 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US10393728B2 (en) | 2002-05-24 | 2019-08-27 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US9897589B2 (en) | 2002-05-24 | 2018-02-20 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US8808551B2 (en) | 2002-05-24 | 2014-08-19 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US10183042B2 (en) | 2002-05-24 | 2019-01-22 | Biomet Manufacturing, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US8696905B2 (en) | 2004-02-23 | 2014-04-15 | Circle Biologics, Inc. | Fluid concentrator |
US9764090B2 (en) | 2004-06-23 | 2017-09-19 | Abbvie Biotechnology Ltd | Relating to automatic injection devices |
US8162887B2 (en) | 2004-06-23 | 2012-04-24 | Abbott Biotechnology Ltd. | Automatic injection devices |
US9017287B2 (en) | 2004-06-23 | 2015-04-28 | Abbvie Biotechnology Ltd | Automatic injection devices |
US8668670B2 (en) | 2004-06-23 | 2014-03-11 | Abbvie Biotechnology Ltd | Automatic injection devices |
US9011687B2 (en) | 2005-04-27 | 2015-04-21 | Biomet Biologics, Llc | Method and apparatus for producing autologous clotting components |
US9486584B2 (en) | 2006-06-30 | 2016-11-08 | Abbvie Biotechnology Ltd. | Automatic injection device |
US8679061B2 (en) * | 2006-06-30 | 2014-03-25 | Abbvie Biotechnology Ltd | Automatic injection device |
US9649579B2 (en) | 2007-04-12 | 2017-05-16 | Hanuman Llc | Buoy suspension fractionation system |
US9138664B2 (en) | 2007-04-12 | 2015-09-22 | Biomet Biologics, Llc | Buoy fractionation system |
US9308224B2 (en) | 2008-02-27 | 2016-04-12 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
US11725031B2 (en) | 2008-02-27 | 2023-08-15 | Biomet Manufacturing, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
US10400017B2 (en) | 2008-02-27 | 2019-09-03 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
US10106587B2 (en) | 2008-02-27 | 2018-10-23 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
US9701728B2 (en) | 2008-02-27 | 2017-07-11 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
US8337711B2 (en) | 2008-02-29 | 2012-12-25 | Biomet Biologics, Llc | System and process for separating a material |
US8801586B2 (en) * | 2008-02-29 | 2014-08-12 | Biomet Biologics, Llc | System and process for separating a material |
US9719063B2 (en) | 2008-02-29 | 2017-08-01 | Biomet Biologics, Llc | System and process for separating a material |
US20100226909A1 (en) * | 2009-03-06 | 2010-09-09 | Biomet Biologics, Llc | Method And Apparatus For Producing Autologous Thrombin |
US8783470B2 (en) | 2009-03-06 | 2014-07-22 | Biomet Biologics, Llc | Method and apparatus for producing autologous thrombin |
US8187475B2 (en) * | 2009-03-06 | 2012-05-29 | Biomet Biologics, Llc | Method and apparatus for producing autologous thrombin |
US8992862B2 (en) | 2009-04-03 | 2015-03-31 | Biomet Biologics, Llc | All-in-one means of separating blood components |
US9561328B2 (en) | 2009-04-29 | 2017-02-07 | Abbvie Biotechnology Ltd | Automatic injection device |
US8636704B2 (en) | 2009-04-29 | 2014-01-28 | Abbvie Biotechnology Ltd | Automatic injection device |
US9011800B2 (en) | 2009-07-16 | 2015-04-21 | Biomet Biologics, Llc | Method and apparatus for separating biological materials |
US9763875B2 (en) | 2009-08-27 | 2017-09-19 | Biomet Biologics, Llc | Implantable device for production of interleukin-1 receptor antagonist |
US8758301B2 (en) | 2009-12-15 | 2014-06-24 | Abbvie Biotechnology Ltd | Firing button for automatic injection device |
US9533090B2 (en) | 2010-04-12 | 2017-01-03 | Biomet Biologics, Llc | Method and apparatus for separating a material |
US9180244B2 (en) | 2010-04-21 | 2015-11-10 | Abbvie Biotechnology Ltd | Wearable automatic injection device for controlled delivery of therapeutic agents |
US9821117B2 (en) | 2010-04-21 | 2017-11-21 | Abbvie Biotechnology Ltd | Wearable automatic injection device for controlled delivery of therapeutic agents |
US9114408B2 (en) | 2010-11-19 | 2015-08-25 | Kensey Nash Corporation | Centrifuge |
US8617042B2 (en) | 2010-11-19 | 2013-12-31 | Kensey Nash Corporation | Methods for separating constituents of biologic liquid mixtures |
US8758211B2 (en) | 2010-11-19 | 2014-06-24 | Kensey Nash Corporation | Centrifuge |
US8747291B2 (en) | 2010-11-19 | 2014-06-10 | Kensey Nash Corporation | Methods for separating constituents of biologic liquid mixtures |
US8469871B2 (en) | 2010-11-19 | 2013-06-25 | Kensey Nash Corporation | Centrifuge |
US8394006B2 (en) | 2010-11-19 | 2013-03-12 | Kensey Nash Corporation | Centrifuge |
US8974362B2 (en) | 2010-11-19 | 2015-03-10 | Kensey Nash Corporation | Centrifuge |
US8870733B2 (en) | 2010-11-19 | 2014-10-28 | Kensey Nash Corporation | Centrifuge |
US10646884B2 (en) | 2010-11-19 | 2020-05-12 | Dsm Ip Assets B.V. | Centrifuge |
US9987638B2 (en) | 2010-11-19 | 2018-06-05 | Dsm Ip Assets, B.V. | Centrifuge |
US11167292B2 (en) | 2010-11-19 | 2021-11-09 | Dsm Ip Assets B.V. | Centrifuge |
US8485958B2 (en) | 2010-11-19 | 2013-07-16 | Kensey Nash Corporation | Systems and methods for separating constituents of biologic liquid mixtures |
US8556794B2 (en) | 2010-11-19 | 2013-10-15 | Kensey Nash Corporation | Centrifuge |
US8562501B2 (en) | 2010-11-19 | 2013-10-22 | Kensey Nash Corporation | Methods for separating constituents of biologic liquid mixtures |
US8317672B2 (en) | 2010-11-19 | 2012-11-27 | Kensey Nash Corporation | Centrifuge method and apparatus |
US9878102B2 (en) | 2011-01-24 | 2018-01-30 | Abbvie Biotechnology Ltd. | Automatic injection devices having overmolded gripping surfaces |
US10806867B2 (en) | 2011-01-24 | 2020-10-20 | E3D Agricultural Cooperative Association Ltd. | Injector |
US9339610B2 (en) | 2011-01-24 | 2016-05-17 | Abbvie Biotechnology Ltd | Removal of needle shield from syringes and automatic injection devices |
US11565048B2 (en) | 2011-01-24 | 2023-01-31 | Abbvie Biotechnology Ltd. | Automatic injection devices having overmolded gripping surfaces |
US9265887B2 (en) | 2011-01-24 | 2016-02-23 | Abbvie Biotechnology Ltd. | Automatic injection devices having overmolded gripping surfaces |
US10022503B2 (en) | 2011-01-24 | 2018-07-17 | Abbvie Biotechnology Ltd | Removal of needle shield from syringes and automatic injection devices |
US8708968B2 (en) | 2011-01-24 | 2014-04-29 | Abbvie Biotechnology Ltd. | Removal of needle shields from syringes and automatic injection devices |
US9011684B2 (en) | 2011-03-07 | 2015-04-21 | Spinesmith Holdings, Llc | Fluid concentrator with removable cartridge |
US9239276B2 (en) | 2011-04-19 | 2016-01-19 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
EP2520316A2 (en) | 2011-05-02 | 2012-11-07 | Biomet Biologics, LLC | Thrombin isolated from blood and blood fractions |
US9011846B2 (en) | 2011-05-02 | 2015-04-21 | Biomet Biologics, Llc | Thrombin isolated from blood and blood fractions |
US8586324B2 (en) * | 2011-08-15 | 2013-11-19 | Biomet Biologics, Llc | Method and apparatus to create autologous clotting serum |
US9815038B2 (en) | 2011-08-15 | 2017-11-14 | Biomet Biologics, Llc | Method and apparatus to create autologous clotting serum |
US10022731B2 (en) * | 2012-01-31 | 2018-07-17 | Argos Therapeutics, Inc. | Centrifuge vessels with a center mound and an internal elongate tube suitable for live cell processing and associated systems and methods |
US20140364296A1 (en) * | 2012-01-31 | 2014-12-11 | Argos Therapeutics, Inc. | Centrifuge vessels suitable for live cell processing and associated systems and methods |
US9120095B2 (en) | 2012-03-29 | 2015-09-01 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating a component of a fluid |
US20160230214A1 (en) * | 2012-04-30 | 2016-08-11 | Life Technologies Corporation | Centrifuge and method for loading a device |
US10781474B2 (en) * | 2012-04-30 | 2020-09-22 | Life Technologies Corporation | Centrifuge with variable angle buckets and method for loading a device |
US9642956B2 (en) | 2012-08-27 | 2017-05-09 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US9480730B2 (en) | 2012-09-25 | 2016-11-01 | Stem Cell Partners Llc | Method and apparatus for preparing single donor thrombin serum |
WO2014149979A1 (en) | 2013-03-15 | 2014-09-25 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
US9758806B2 (en) | 2013-03-15 | 2017-09-12 | Biomet Biologics, Llc | Acellular compositions for treating inflammatory disorders |
US10441634B2 (en) | 2013-03-15 | 2019-10-15 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
WO2014144505A2 (en) | 2013-03-15 | 2014-09-18 | Biomet Biologics, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
EP3351253A1 (en) | 2013-03-15 | 2018-07-25 | Biomet Biologics, LLC | Method for making an autologous protein solution |
US9556243B2 (en) | 2013-03-15 | 2017-01-31 | Biomet Biologies, LLC | Methods for making cytokine compositions from tissues using non-centrifugal methods |
WO2014149300A1 (en) | 2013-03-15 | 2014-09-25 | Biomet Biologics, Llc | Treatment of inflammatory respiratory disease using biological solutions |
US10143725B2 (en) | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
WO2014149270A1 (en) | 2013-03-15 | 2014-09-25 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
EP3881852A1 (en) | 2013-03-15 | 2021-09-22 | Biomet Biologics, LLC | Treatment of pain using protein solutions |
US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
US9878011B2 (en) | 2013-03-15 | 2018-01-30 | Biomet Biologics, Llc | Treatment of inflammatory respiratory disease using biological solutions |
WO2014149301A1 (en) | 2013-03-15 | 2014-09-25 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
US11957733B2 (en) | 2013-03-15 | 2024-04-16 | Biomet Manufacturing, Llc | Treatment of collagen defects using protein solutions |
US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
US10576130B2 (en) | 2013-03-15 | 2020-03-03 | Biomet Manufacturing, Llc | Treatment of collagen defects using protein solutions |
US10946043B2 (en) | 2013-11-26 | 2021-03-16 | Biomet Biologics, Llc | Methods of mediating macrophage phenotypes |
US9833474B2 (en) | 2013-11-26 | 2017-12-05 | Biomet Biologies, LLC | Methods of mediating macrophage phenotypes |
WO2015081253A1 (en) | 2013-11-26 | 2015-06-04 | Biomet Biologics, Llc | Methods of mediating macrophage phenotypes |
US10711239B2 (en) | 2014-01-31 | 2020-07-14 | Dsm Ip Assets B.V. | Adipose tissue centrifuge and method of use |
US10125345B2 (en) | 2014-01-31 | 2018-11-13 | Dsm Ip Assets, B.V. | Adipose tissue centrifuge and method of use |
US11549094B2 (en) | 2014-01-31 | 2023-01-10 | Dsm Ip Assets B.V. | Adipose tissue centrifuge and method of use |
US9550028B2 (en) | 2014-05-06 | 2017-01-24 | Biomet Biologics, LLC. | Single step desiccating bead-in-syringe concentrating device |
US10441635B2 (en) | 2014-11-10 | 2019-10-15 | Biomet Biologics, Llc | Methods of treating pain using protein solutions |
US10729552B2 (en) | 2015-03-18 | 2020-08-04 | Biomet C.V. | Implant configured for hammertoe and small bone fixation |
US9713810B2 (en) | 2015-03-30 | 2017-07-25 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
USD838863S1 (en) * | 2015-04-07 | 2019-01-22 | Nissan Chemical Industries, Ltd. | Liquid mixing container |
US9757721B2 (en) | 2015-05-11 | 2017-09-12 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
US10960114B2 (en) * | 2015-10-14 | 2021-03-30 | Mario GOISIS | Fat filtration device |
Also Published As
Publication number | Publication date |
---|---|
US20140034567A1 (en) | 2014-02-06 |
US9011687B2 (en) | 2015-04-21 |
US20100198130A1 (en) | 2010-08-05 |
EP1716901A1 (en) | 2006-11-02 |
JP5183883B2 (en) | 2013-04-17 |
US20060243676A1 (en) | 2006-11-02 |
JP2006305365A (en) | 2006-11-09 |
EP1716901B1 (en) | 2015-03-25 |
US8551344B2 (en) | 2013-10-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US7694828B2 (en) | Method and apparatus for producing autologous clotting components | |
US8512575B2 (en) | Method and apparatus for collecting biological materials | |
EP3031525B1 (en) | Apparatus and method for separating and concentrating fluids containing multiple components | |
JP4510898B2 (en) | Plasma concentrator | |
US9388377B2 (en) | Regenerative cell extraction unit and regenerative cell extraction system | |
US7374678B2 (en) | Apparatus and method for separating and concentrating fluids containing multiple components | |
US8163184B2 (en) | Apparatus and method for separating and concentrating fluids containing multiple components | |
US8808551B2 (en) | Apparatus and method for separating and concentrating fluids containing multiple components | |
US20070075016A1 (en) | Method and apparatus for collecting biological materials | |
KR20110120729A (en) | Buffy coat sampling kit and method using the same | |
US20230381792A1 (en) | Portable Centrifuge Apparatus & Methods | |
WO2007141255A1 (en) | Improved disposable device for centrifuging and treating a fluid biological material | |
US10501715B1 (en) | System for the formation of fibrin foam | |
CA3207550A1 (en) | Portable centrifuge apparatus & methods | |
JP2009545374A (en) | Apparatus and method for preparing platelet-enriched plasma and concentrates thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: BIOMET MANUFACTURING CORP.,INDIANA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:SWIFT, MATTHEW J.;LEACH, MICHAEL D.;HECKER, BARRY F.;SIGNING DATES FROM 20050412 TO 20050425;REEL/FRAME:016520/0498 Owner name: BIOMET MANUFACTURING CORP., INDIANA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:SWIFT, MATTHEW J.;LEACH, MICHAEL D.;HECKER, BARRY F.;REEL/FRAME:016520/0498;SIGNING DATES FROM 20050412 TO 20050425 |
|
AS | Assignment |
Owner name: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT FOR Free format text: SECURITY AGREEMENT;ASSIGNORS:LVB ACQUISITION, INC.;BIOMET, INC.;REEL/FRAME:020362/0001 Effective date: 20070925 |
|
STCF | Information on status: patent grant |
Free format text: PATENTED CASE |
|
AS | Assignment |
Owner name: BIOMET BIOLOGICS, LLC, INDIANA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BIOMET MANUFACTURING CORP.;REEL/FRAME:026258/0514 Effective date: 20110207 |
|
FPAY | Fee payment |
Year of fee payment: 4 |
|
AS | Assignment |
Owner name: LVB ACQUISITION, INC., INDIANA Free format text: RELEASE OF SECURITY INTEREST IN PATENTS RECORDED AT REEL 020362/ FRAME 0001;ASSIGNOR:BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT;REEL/FRAME:037155/0133 Effective date: 20150624 Owner name: BIOMET, INC., INDIANA Free format text: RELEASE OF SECURITY INTEREST IN PATENTS RECORDED AT REEL 020362/ FRAME 0001;ASSIGNOR:BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT;REEL/FRAME:037155/0133 Effective date: 20150624 |
|
MAFP | Maintenance fee payment |
Free format text: PAYMENT OF MAINTENANCE FEE, 8TH YEAR, LARGE ENTITY (ORIGINAL EVENT CODE: M1552) Year of fee payment: 8 |
|
AS | Assignment |
Owner name: BIOMET MANUFACTURING, LLC, INDIANA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:ZB MANUFACTURING, LLC;REEL/FRAME:045914/0335 Effective date: 20171103 Owner name: BIOMET, INC., INDIANA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BIOMET BIOLOGICS, LLC;REEL/FRAME:045914/0262 Effective date: 20171103 Owner name: ZB MANUFACTURING, LLC, INDIANA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BIOMET, INC.;REEL/FRAME:045914/0350 Effective date: 20171103 |
|
FEPP | Fee payment procedure |
Free format text: MAINTENANCE FEE REMINDER MAILED (ORIGINAL EVENT CODE: REM.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
|
LAPS | Lapse for failure to pay maintenance fees |
Free format text: PATENT EXPIRED FOR FAILURE TO PAY MAINTENANCE FEES (ORIGINAL EVENT CODE: EXP.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
|
STCH | Information on status: patent discontinuation |
Free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362 |
|
FP | Lapsed due to failure to pay maintenance fee |
Effective date: 20220413 |