US7191006B2 - Cardiac rhythm management systems and methods for rule-illustrative parameter entry - Google Patents

Cardiac rhythm management systems and methods for rule-illustrative parameter entry Download PDF

Info

Publication number
US7191006B2
US7191006B2 US10/310,702 US31070202A US7191006B2 US 7191006 B2 US7191006 B2 US 7191006B2 US 31070202 A US31070202 A US 31070202A US 7191006 B2 US7191006 B2 US 7191006B2
Authority
US
United States
Prior art keywords
parameter
rule
programmed
value
parameters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime, expires
Application number
US10/310,702
Other versions
US20040111131A1 (en
Inventor
Bo Hu
Wei Cao
Allan T. Koshiol
James Kalgren
Paula Dieterle
Par Lindh
Les Peterson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardiac Pacemakers Inc
Original Assignee
Cardiac Pacemakers Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiac Pacemakers Inc filed Critical Cardiac Pacemakers Inc
Priority to US10/310,702 priority Critical patent/US7191006B2/en
Assigned to CARDIAC PACEMAKERS, INC. reassignment CARDIAC PACEMAKERS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: LINDH, PAR, KOSHIOL, ALLAN T., DIETERLE, PAULA, PETERSON, LES, CAO, WEI, HU, BO, KALGREN, JAMES
Publication of US20040111131A1 publication Critical patent/US20040111131A1/en
Application granted granted Critical
Publication of US7191006B2 publication Critical patent/US7191006B2/en
Adjusted expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372Arrangements in connection with the implantation of stimulators
    • A61N1/37211Means for communicating with stimulators
    • A61N1/37235Aspects of the external programmer
    • A61N1/37247User interfaces, e.g. input or presentation means

Definitions

  • This document relates generally to medical systems, devices, and methods, and particularly, but not by way of limitation, to cardiac rhythm management systems and methods for rule-illustrative parameter entry.
  • the human heart When functioning properly, the human heart maintains its own intrinsic rhythm. Its sinoatrial node generates intrinsic electrical cardiac signals that depolarize the atria, causing atrial heart contractions. Its atrioventricular node then passes the intrinsic cardiac signal to depolarize the ventricles, causing ventricular heart contractions.
  • These intrinsic cardiac signals can be sensed on a surface electrocardiogram (i.e., a “surface ECG signal”) obtained from electrodes placed on the patient's skin, or from electrodes implanted within the patient's body (i.e., an “electrogram signal”).
  • the surface ECG and electrogram waveforms for example, include artifacts associated with atrial depolarizations (“P-waves”) and those associated with ventricular depolarizations (“QRS complexes”).
  • a normal heart is capable of pumping adequate blood throughout the body's circulatory system.
  • cardiac arrhythmias some people have irregular cardiac rhythms, referred to as cardiac arrhythmias.
  • cardiac arrhythmias some patients have poor spatial coordination of heart contractions. In either case, diminished blood circulation may result.
  • a cardiac rhythm management system may be used to improve the rhythm and/or spatial coordination of heart contractions.
  • Such systems often include a cardiac rhythm management device that is implanted in the patient to deliver therapy to the heart.
  • Pacers deliver timed sequences of low energy electrical stimuli, called pace pulses, to the heart, such as via an intravascular lead wire or catheter (referred to as a “lead”) having one or more electrodes disposed in or about the heart. Heart contractions are initiated in response to such pace pulses (this is referred to as “capturing” the heart). By properly timing the delivery of pace pulses, the heart can be induced to contract in proper rhythm, greatly improving its efficiency as a pump. Pacers are often used to treat patients with bradyarrhythmias, that is, hearts that beat too slowly, or irregularly. Such pacers may also coordinate atrial and ventricular contractions to improve pumping efficiency.
  • Cardiac rhythm management systems also include cardiac resynchronization therapy (CRT) devices for coordinating the spatial nature of heart depolarizations for improving pumping efficiency.
  • CRT cardiac resynchronization therapy
  • a CRT device may deliver appropriately timed pace pulses to different locations of the same heart chamber to better coordinate the contraction of that heart chamber, or the CRT device may deliver appropriately timed pace pulses to different heart chambers to improve the manner in which these different heart chambers contract together.
  • Cardiac rhythm management systems also include defibrillators that are capable of delivering higher energy electrical stimuli to the heart.
  • defibrillators include cardioverters, which typically synchronize the delivery of such stimuli to sensed intrinsic heart activity signals.
  • Defibrillators are often used to treat patients with tachyarrhythmias, that is, hearts that beat too quickly. Such too-fast heart rhythms also cause diminished blood circulation because the heart isn't allowed sufficient time to fill with blood before contracting to expel the blood. Such pumping by the heart is inefficient.
  • a defibrillator is capable of delivering a high energy electrical stimulus that is sometimes referred to as a defibrillation countershock, also referred to simply as a “shock.”
  • the shock interrupts the tachyarrhythmia, allowing the heart to reestablish a normal rhythm for the efficient pumping of blood.
  • cardiac rhythm management systems also include devices that combine these functions, as well as monitors, drug delivery devices, and any other implantable or external systems or devices for diagnosing or treating the heart.
  • Cardiac rhythm management systems often include external remote user interfaces (sometimes referred to as “programmers”) for programming parameters of an implantable cardiac rhythm management device and/or receiving data telemetered from the implantable cardiac rhythm management device.
  • One problem faced by cardiac rhythm management systems is in using an external remote user interface to program parameters of the implantable cardiac rhythm management device to tailor the therapy delivered by the implantable cardiac rhythm management device to the needs of the particular subject being treated by that device.
  • Programmable implantable cardiac rhythm management devices often make use of a plethora of programmable parameters.
  • programmable parameters may interact with each other. For example, programming a first parameter to a particular value may limit the range of particular values to which a second parameter may be programmed. Because of this interaction between different programmable parameters, a complex set of rules typically governs how the set of parameters may be programmed. Consequently, a physician faces a daunting task in programming the whole set of parameters to self-consistent values.
  • FIG. 1 is a schematic diagram illustrating generally, by way of example, but not by way of limitation, portions of a cardiac rhythm management system.
  • FIG. 2 is a screen shot of a portion of display, including, by way of example, but not by way of limitation, one embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of a device.
  • FIG. 3 is a screen shot of an alternative portion of a display, including, by way of example, but not by way of limitation, one embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of a device.
  • FIG. 4 illustrates the screen shot of FIG. 3 in which a first rule violation is flagged.
  • FIG. 5 illustrates the screen shot of FIG. 3 in which a second rule violation is flagged.
  • FIG. 6 illustrates the screen shot of FIG. 5 in which the display includes a further explanation of the flagged second rule violation.
  • FIG. 7 is a screen shot of a portion of a display, similar to FIG. 3 , but including a graphical parameter selector icon.
  • FIGS. 8A and 8B are screen shots of alternative portions of a display illustrating generally another embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of a device based on a value of a different parameter.
  • FIGS. 9A and 9B are screen shots of alternative portions of a display illustrating generally another embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of a device.
  • implantable medical devices including, but not limited to, implantable cardiac rhythm management systems such as pacemakers, cardioverter/defibrillators, pacer/defibrillators, biventricular or other multi-site resynchronization or coordination devices, and drug delivery systems.
  • implantable cardiac rhythm management systems such as pacemakers, cardioverter/defibrillators, pacer/defibrillators, biventricular or other multi-site resynchronization or coordination devices, and drug delivery systems.
  • these systems, devices, and methods may be employed in unimplanted devices, including, but not limited to, external pacemakers, cardioverter/defibrillators, pacer/defibrillators, biventricular or other multi-site resynchronization or coordination devices, monitors, programmers and recorders, whether such devices are used for providing a diagnostic, a therapy, or both a diagnostic and a therapy.
  • FIG. 1 is a block diagram illustrating generally portions of a cardiac rhythm management system 100 and portions of an environment in which it is used.
  • system 100 includes a cardiac rhythm management device 102 coupled to a heart 104 by one or more electrodes associated with heart 104 , such as for sensing intrinsic cardiac signals and/or for delivering energy or other therapy to heart 104 .
  • System 100 also includes a remote external programmer 106 .
  • Programmer 106 includes a telemetry or other communication circuit 108 , which is wirelessly or otherwise communicatively coupled to a telemetry or other communication circuit in device 102 .
  • Device 102 includes (by way of example, but not by way of limitation) a pacer, a defibrillator, a cardiac resynchronization therapy (CRT) device, a monitor, a device that combines more than one of these functions, or any other implantable or external device for diagnosing and/or treating the heart.
  • device 102 is sized and shaped for being pectorally or abdominally implanted in a human patient.
  • the electrode(s) coupling device 102 to heart 104 may include an intravascular electrode, an intracardiac electrode, an epicardial electrode, or a housing or a header electrode located on a housing of device 102 or a header attached thereto, or any combination of the above.
  • the electrode(s) coupling device 102 to heart 104 may include a skin surface electrode external to the patient.
  • the electrodes may be associated with the heart for bipolar (i.e., two electrodes that are relatively close together) or for unipolar (i.e., two electrodes that are farther apart) signal sensing or therapy energy delivery (e.g., pacing pulse or shocks).
  • programmer 106 includes a controller or processor that is capable of sequencing through various control states such as, for example, by using a digital microprocessor having executable instructions stored in an associated instruction memory circuit, a microsequencer, or a state machine.
  • the controller or processor typically also includes, or is coupled to, a memory circuit for storing data.
  • Programmer 106 also includes a user input/output interface 110 , which includes a display 112 .
  • a physician or other caregiver uses user interface 110 for programming therapy and other operative parameters of device 102 . As discussed above, such parameters are often subject to a complex set of rules governing how they interact with each other.
  • FIG. 2 is a screen shot of a portion of display 112 , including, by way of example, but not by way of limitation, one embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of device 102 .
  • display 112 includes a graphical indication of the at least one parameter to be programmed.
  • three cardiac rhythm management therapy parameters are presented: a post-ventricular atrial refractory period (PVARP), a atrio-ventricular (AV) delay, and a maximum tracking rate (MTR). These particular parameters are presented by way of example only, and not by way of limitation.
  • PVARP post-ventricular atrial refractory period
  • AV atrio-ventricular
  • MTR maximum tracking rate
  • the PVARP defines the length of time (“refractory period”) after a paced or sensed ventricular contraction during which any atrial contraction, sensed from an atrial electrode, will be ignored.
  • the AV delay defines a timeout after a paced or sensed atrial contraction after which a ventricular pacing pulse will be delivered if no ventricular contraction has been sensed during the AV delay.
  • the MTR defines a time interval corresponding to a maximum pacing rate, wherein information received from a physiologic sensor is only allowed to drive the patient's pacing rate up to that MTR rate limit.
  • the graphical indication is presented in the form of a bar graph icon, such as PVARP icon 200 , AV delay icon 202 , and MTR icon 204 .
  • the length of the bar graph icon represents the programmably adjustable value of the corresponding parameter.
  • these values are expressed in terms of time intervals, with an optional corresponding indication of rate provided to assist the user in translating between time interval and rate.
  • the value represented by PVARP icon 200 is 300 milliseconds
  • the value represented by AV Delay icon 202 is 290 milliseconds
  • the value represented by MTR icon 204 is 500 milliseconds.
  • MTR icon 204 also presents the corresponding represented value expressed in terms of rate, i.e., 120 beats per minute (bpm).
  • the parameter icons are “draggable” (e.g., using a computer mouse cursor on display 112 , or using a finger on a touch-screen display 112 ) to change the value of the parameter represented by the icon by dragging an edge of the bar graph parameter icon to increase or decrease its length.
  • this is represented by triangles located at an edge of a bar graph icon; the triangles are pointing in opposite directions to indicate to the user that the length of the bar graph parameter icon can be increased or decreased to change the underlying parameter value.
  • the parameter icons are presented in visual correspondence with one another to illustrate to the user a particular rule imposing a limitation on the value of at least one of the parameters.
  • the illustrated rule represents a relationship between the allowable time intervals of the PVARP, AV delay, and MTR parameters. More particularly, the rule requires that the sum of PVARP and AV delay not exceed the MTR. This is illustrated by presenting PVARP icon 200 and AV Delay icon 202 side-by-side such that their lengths are additively illustrated, and presenting MTR icon 204 , in visual correspondence therewith, such as immediately below PVARP icon 200 and AV Delay icon 202 . In this way, the sum of the lengths of PVARP icon 200 and AV Delay icon 202 can be visually compared to the limit imposed by the length of MTR icon 204 .
  • a graphical indication flags when the rule has been violated.
  • a color of the icons and/or the background may change (e.g., from green to red) when a rule violation occurs.
  • a graphical corrective indication indicates how the rule violation can be corrected.
  • this corrective indication includes arrows 206 and 208 .
  • Arrow 206 indicates that the illustrated rule violation can be corrected by decreasing the values of one of PVARP and AV Delay, such that the sum of PVARP and AV Delay no longer exceeds the MTR.
  • Arrow 208 indicates that the illustrated rule violation can alternatively be corrected by increasing the value of MTR such that it exceeds the sum of PVARP and AV Delay.
  • FIG. 2 also illustrates icons for organizing therapy and other operative parameters for selection and display by the user.
  • FIG. 2 includes “Brady Parameters” icon 210 A, “Tachy Parameters” icon 210 B, and “Other Parameters” icon 210 C.
  • “clicking” on one of these icons using a mouse cursor triggers a rule-illustrative display of one or more corresponding parameters or, alternatively, a menu for selectively displaying one or more such rule-illustrative parameters.
  • FIG. 3 is a screen shot of an alternative portion of display 112 , including, by way of example, but not by way of limitation, one embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of device 102 .
  • display 112 illustrates all rules that are associated with at least one particular parameter being programmed.
  • the parameter being programmed in is PVARP, which, in one example, is divided into two sub-parameters, i.e., a minimum PVARP (“Min PVARP”) and a maximum PVARP (“Max PVARP”).
  • Min PVARP minimum PVARP
  • Max PVARP maximum PVARP
  • FIG. 3 is intended to illustrate an example in which display 112 provides a graphical illustration of each rule governing PVARP (i.e., governing Min PVARP or governing Max PVARP).
  • PVARP rule governing the parameter being programmed
  • FIG. 3 presents an illustrative example of such rules, it is understood that all rules governing the parameter being programmed (e.g., PVARP) need not be displayed concurrently. For example, if the number of rules to be displayed exceeds the available screen space, display 112 provides a scrollbar or other user-accessible device for obtaining or selecting particular rules for display and/or programming.
  • display 112 includes a bar graph Min PVARP icon 300 and a bar graph Max PVARP icon 302 , the length of each indicating its value in milliseconds. As discussed above, the user can programmably adjust these values by “dragging” an edge of the Min PVARP icon 300 or the Max PVARP icon 302 to change its length, thereby increasing or decreasing the corresponding parameter value.
  • display 112 includes four graphical rule indications 304 A–D. Each graphical rule indication 304 A–D graphically illustrates a rule involving the parameter being programmed (in this case PVARP, which comprises two sub-parameters Min PVARP and Max PVARP).
  • Min PVARP icon 300 or Max PVARP icon 302 As the user adjusts the length of Min PVARP icon 300 or Max PVARP icon 302 , a corresponding length of the same sub-parameter is simultaneously changed in the applicable graphical rule indications 304 A–D. This allows the user to visualize how changing a parameter is affected by all the rules related to that parameter. It further enables the user to visualize which rule is violated, if any, how close other rules are to being violated, which other parameters affect those rules, and how the values of those other parameters could be adjusted to avoid violation of one or more rules.
  • graphical rule indication 304 A indicates a rule in which the sum of a Minimum AV Delay (“Min AV Delay”) parameter and Min PVARP must not exceed the Maximum Tracking Rate Interval (MTRI).
  • Graphical rule indication 304 B indicates a rule in which the Min PVARP must not exceed 1 ⁇ 2 of the MTRI.
  • Graphical rule indication 304 C indicates a rule in which the sum of a maximum AV Delay (“Max AV Delay”) and Max PVARP must not exceed a Lower Rate Limit Interval (LRLI).
  • Min AV Delay Minimum AV Delay
  • MTRI Maximum Tracking Rate Interval
  • Graphical rule indication 304 D indicates a rule in which the sum of an Atrial Fibrillation Rate Interval (AFRI), a Left Ventricular Offset (LV Offset), and a 50 millisecond constant must not exceed a difference between LRLI and a margin parameter (“Delta”).
  • AFRI Atrial Fibrillation Rate Interval
  • LV Offset Left Ventricular Offset
  • Delta margin parameter
  • the user has dragged the edge of the Min PVARP icon 300 to increase its value from 180 milliseconds to 220 milliseconds.
  • the second illustrated rule (indicated by graphical rule indication 304 B) has been violated since Min PVARP now exceeds MTRI/2.
  • the background of graphical rule indication 304 B has changed shading or color (e.g., from white to yellow).
  • the user has dragged the edge of the Max PVARP icon 302 to increase its value from 260 milliseconds to 350 milliseconds.
  • the fourth illustrated rule (indicated by graphical rule indication 304 D) has been violated since the sum of AFRI, LV Offset, a 50 millisecond constant, and Max PVARP now exceeds the limit imposed by LRLI—Delta, illustrated immediately below that sum.
  • the background of graphical rule indication 304 D has changed shading or color (e.g., from white to red). In one example, different colors of changed shading in response to a rule violation convey different information.
  • a changed background shading from white to yellow may indicate violation of a recommended rule
  • a changed background from white to red may indicate violation of an absolute rule.
  • a user is allowed to program a combination of parameter values that violates a recommended rule, but is not allowed to program a combination of parameter values that violates an absolute rule.
  • display 112 also includes a “Rationale” button 306 A–D corresponding to each graphical rule indication 304 A–D.
  • display 112 provides a box 600 that provides further textual or graphical information relating to that graphically-illustrated rule, as illustrated in the example of FIG. 6 , for which the user has selected “Rationale” button 306 D.
  • display 112 discontinues its display of box 600 .
  • FIG. 7 is a screen shot of a portion of a display, similar to FIG. 3 , but including a graphical parameter selector icon 700 .
  • Parameter selector icon 700 allows the user to select between different (related or unrelated) parameters, triggering a corresponding display of graphical illustrations of one or more rules associated with the selected parameter.
  • parameter selector icon 700 includes a button menu for selecting either “Dynamic PVARP” or “Fixed PVARP.”
  • the parameters “Dynamic PVARP” and “Fixed PVARP” are related in the sense that both apply to a PVARP, as discussed above.
  • the value of the “Dynamic PVARP” parameter is a function of the patient's underlying heart rate and is, therefore, subject to an at least partially different set of rules governing the PVARP parameter.
  • Patient selector icon 700 triggers display of graphical indications of the appropriate set of rules corresponding to the one of “Dynamic PVARP” and “Fixed PVARP” selector, and allows graphical adjustment of one or more parameters affected by the displayed rules.
  • FIGS. 8A and 8B are screen shots of alternative portions of a display 112 that includes, by way of example, but not by way of limitation, another embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of a device 102 based on a value of a different parameter.
  • FIG. 8A illustrates an example of a display 112 that includes at least two parameter icons.
  • a first parameter icon 800 indicates graphically whether a binary-valued parameter, “Feature A,” is on or off.
  • a second parameter icon 802 indicates graphically a value of a range parameter, “Parameter B.”
  • icon 802 is a bar graph having a length that graphically indicates the value of “Parameter B” (the value is also indicated textually on icon 802 ).
  • Icon 802 also allows the value of “Parameter B” to be adjusted by dragging an edge of the bar graph icon 802 , such as discussed above.
  • the displayed length of the bar graph icon 802 represents graphically to the user the value to which “Parameter B” is being programmed; in this example, the changing value is also indicated textually on bar graph icon 802 .
  • FIG. 8A illustrates an example of a rule being violated.
  • the rule violation triggers the illustrated textual description of the rule violation.
  • the range of values to which “Parameter B” can be programmed is limited.
  • the occurrence of the rule violation is flagged graphically, such as by changing a background color, as discussed above.
  • the example illustrated in FIG. 8A also includes a displayed corrective action indicator 804 .
  • the corrective action indicator 804 includes an arrow indicating the direction that the edge of bar graph icon 802 should be dragged to change the underlying value of “Parameter B” such that the rule is no longer violated; such a result is illustrated in FIG. 8B .
  • FIGS. 9A and 9B are screen shots of alternative portions of a display 112 , including, by way of example, but not by way of limitation, another embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of a device 102 .
  • the example of FIG. 9A illustrates three parameter icons 900 A, 900 B, and 900 C, respectively corresponding to the binary-valued (e.g., “on/off”) parameters “Feature A,” “Feature B,” and “Feature C.”
  • a rule governing these three parameters indicates that only one of these “Feature A,” “Feature B,” and “Feature C” can be on at one time.
  • the three parameter icons 900 A–C are presented in visual correspondence with each other, so that the user can easily determine how to resolve an underlying rule violation.
  • the parameter icons 900 A–C are displayed as user-selectable “buttons” that can be selected to toggle the value of the particular parameter corresponding to the icon between “on” and “off” to correct the rule violation; such a result is illustrated by the example of FIG. 9B .
  • a textual description of the underlying rule or rule violation is presented.
  • a graphical indication flags rule violation, such as by a change in background color or other technique, as discussed above.
  • a graphical indication of corrective action is presented, such as, in this example, arrows pointing to the more than one feature that is “on” simultaneously in violation of the rule.

Abstract

This document describes systems, devices, and methods for programmably adjusting therapy or other operative parameter values of an implantable cardiac rhythm management device using a programmer that includes a display that graphically illustrates one or more relationship between a parameter being programmed and other parameters and/or rules governing interactions between parameters.

Description

COPYRIGHT NOTICE
A portion of the disclosure of this patent document contains material that is subject to copyright protection. The copyright owner has no objection to the facsimile reproduction by anyone of the patent document or the patent disclosure, as it appears in the Patent and Trademark Office patent files or records, but otherwise reserves all copyright rights whatsoever.
TECHNICAL FIELD
This document relates generally to medical systems, devices, and methods, and particularly, but not by way of limitation, to cardiac rhythm management systems and methods for rule-illustrative parameter entry.
BACKGROUND
When functioning properly, the human heart maintains its own intrinsic rhythm. Its sinoatrial node generates intrinsic electrical cardiac signals that depolarize the atria, causing atrial heart contractions. Its atrioventricular node then passes the intrinsic cardiac signal to depolarize the ventricles, causing ventricular heart contractions. These intrinsic cardiac signals can be sensed on a surface electrocardiogram (i.e., a “surface ECG signal”) obtained from electrodes placed on the patient's skin, or from electrodes implanted within the patient's body (i.e., an “electrogram signal”). The surface ECG and electrogram waveforms, for example, include artifacts associated with atrial depolarizations (“P-waves”) and those associated with ventricular depolarizations (“QRS complexes”).
A normal heart is capable of pumping adequate blood throughout the body's circulatory system. However, some people have irregular cardiac rhythms, referred to as cardiac arrhythmias. Moreover, some patients have poor spatial coordination of heart contractions. In either case, diminished blood circulation may result. For such patients, a cardiac rhythm management system may be used to improve the rhythm and/or spatial coordination of heart contractions. Such systems often include a cardiac rhythm management device that is implanted in the patient to deliver therapy to the heart.
Cardiac rhythm management systems include, among other things, pacemakers, also referred to as pacers. Pacers deliver timed sequences of low energy electrical stimuli, called pace pulses, to the heart, such as via an intravascular lead wire or catheter (referred to as a “lead”) having one or more electrodes disposed in or about the heart. Heart contractions are initiated in response to such pace pulses (this is referred to as “capturing” the heart). By properly timing the delivery of pace pulses, the heart can be induced to contract in proper rhythm, greatly improving its efficiency as a pump. Pacers are often used to treat patients with bradyarrhythmias, that is, hearts that beat too slowly, or irregularly. Such pacers may also coordinate atrial and ventricular contractions to improve pumping efficiency.
Cardiac rhythm management systems also include cardiac resynchronization therapy (CRT) devices for coordinating the spatial nature of heart depolarizations for improving pumping efficiency. For example, a CRT device may deliver appropriately timed pace pulses to different locations of the same heart chamber to better coordinate the contraction of that heart chamber, or the CRT device may deliver appropriately timed pace pulses to different heart chambers to improve the manner in which these different heart chambers contract together.
Cardiac rhythm management systems also include defibrillators that are capable of delivering higher energy electrical stimuli to the heart. Such defibrillators include cardioverters, which typically synchronize the delivery of such stimuli to sensed intrinsic heart activity signals. Defibrillators are often used to treat patients with tachyarrhythmias, that is, hearts that beat too quickly. Such too-fast heart rhythms also cause diminished blood circulation because the heart isn't allowed sufficient time to fill with blood before contracting to expel the blood. Such pumping by the heart is inefficient. A defibrillator is capable of delivering a high energy electrical stimulus that is sometimes referred to as a defibrillation countershock, also referred to simply as a “shock.” The shock interrupts the tachyarrhythmia, allowing the heart to reestablish a normal rhythm for the efficient pumping of blood. In addition to pacers, CRT devices, and defibrillators, cardiac rhythm management systems also include devices that combine these functions, as well as monitors, drug delivery devices, and any other implantable or external systems or devices for diagnosing or treating the heart. Cardiac rhythm management systems often include external remote user interfaces (sometimes referred to as “programmers”) for programming parameters of an implantable cardiac rhythm management device and/or receiving data telemetered from the implantable cardiac rhythm management device.
One problem faced by cardiac rhythm management systems is in using an external remote user interface to program parameters of the implantable cardiac rhythm management device to tailor the therapy delivered by the implantable cardiac rhythm management device to the needs of the particular subject being treated by that device. Programmable implantable cardiac rhythm management devices often make use of a plethora of programmable parameters. Moreover, such programmable parameters may interact with each other. For example, programming a first parameter to a particular value may limit the range of particular values to which a second parameter may be programmed. Because of this interaction between different programmable parameters, a complex set of rules typically governs how the set of parameters may be programmed. Consequently, a physician faces a daunting task in programming the whole set of parameters to self-consistent values. Moreover, as new therapies are developed (e.g., congestive heart failure therapies that treat both left and right sides of the heart), more parameters and more interactions between parameters are inevitable, further complicating the task of programming a complete set of parameters to allowable values. For these and other reasons, the present inventors have recognized a need for improved techniques for assisting a physician, caregiver, or other user in programming one or more parameters of an implantable cardiac rhythm management device.
BRIEF DESCRIPTION OF THE DRAWINGS
In the drawings, which are offered by way of example, and not by way of limitation, and which are not necessarily drawn to scale, like numerals describe substantially similar components throughout the several views. Like numerals having different letter suffixes represent different instances of substantially similar components.
FIG. 1 is a schematic diagram illustrating generally, by way of example, but not by way of limitation, portions of a cardiac rhythm management system.
FIG. 2 is a screen shot of a portion of display, including, by way of example, but not by way of limitation, one embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of a device.
FIG. 3 is a screen shot of an alternative portion of a display, including, by way of example, but not by way of limitation, one embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of a device.
FIG. 4 illustrates the screen shot of FIG. 3 in which a first rule violation is flagged.
FIG. 5 illustrates the screen shot of FIG. 3 in which a second rule violation is flagged.
FIG. 6 illustrates the screen shot of FIG. 5 in which the display includes a further explanation of the flagged second rule violation.
FIG. 7 is a screen shot of a portion of a display, similar to FIG. 3, but including a graphical parameter selector icon.
FIGS. 8A and 8B are screen shots of alternative portions of a display illustrating generally another embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of a device based on a value of a different parameter.
FIGS. 9A and 9B are screen shots of alternative portions of a display illustrating generally another embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of a device.
DETAILED DESCRIPTION
In the following detailed description, reference is made to the accompanying drawings, which form a part hereof, and in which is shown by way of illustration specific embodiments in which the invention may be practiced. These embodiments are described in sufficient detail to enable those skilled in the art to practice the invention, and it is to be understood that the embodiments may be combined, or that other embodiments may be utilized and that structural, logical and electrical changes may be made without departing from the scope of the present invention. The following detailed description is, therefore, not to be taken in a limiting sense, and the scope of the present invention is defined by the appended claims and their equivalents.
In this document, the terms “a” or “an” are used, as is common in patent documents, to include one or more than one. Furthermore, all publications, patents, and patent documents referred to in this document are incorporated by reference herein in their entirety, as though individually incorporated by reference. In the event of inconsistent usages between this documents and those documents so incorporated by reference, the usage in the incorporated reference(s) should be considered supplementary to that of this document; for irreconcilable inconsistencies, the usage in this document controls.
This document discusses, among other things, systems, devices, and methods that will be described in applications involving implantable medical devices including, but not limited to, implantable cardiac rhythm management systems such as pacemakers, cardioverter/defibrillators, pacer/defibrillators, biventricular or other multi-site resynchronization or coordination devices, and drug delivery systems. However, these systems, devices, and methods may be employed in unimplanted devices, including, but not limited to, external pacemakers, cardioverter/defibrillators, pacer/defibrillators, biventricular or other multi-site resynchronization or coordination devices, monitors, programmers and recorders, whether such devices are used for providing a diagnostic, a therapy, or both a diagnostic and a therapy.
FIG. 1 is a block diagram illustrating generally portions of a cardiac rhythm management system 100 and portions of an environment in which it is used. In this example, system 100 includes a cardiac rhythm management device 102 coupled to a heart 104 by one or more electrodes associated with heart 104, such as for sensing intrinsic cardiac signals and/or for delivering energy or other therapy to heart 104. System 100 also includes a remote external programmer 106. Programmer 106 includes a telemetry or other communication circuit 108, which is wirelessly or otherwise communicatively coupled to a telemetry or other communication circuit in device 102. Device 102 includes (by way of example, but not by way of limitation) a pacer, a defibrillator, a cardiac resynchronization therapy (CRT) device, a monitor, a device that combines more than one of these functions, or any other implantable or external device for diagnosing and/or treating the heart. In one example, device 102 is sized and shaped for being pectorally or abdominally implanted in a human patient. The electrode(s) coupling device 102 to heart 104 may include an intravascular electrode, an intracardiac electrode, an epicardial electrode, or a housing or a header electrode located on a housing of device 102 or a header attached thereto, or any combination of the above. In some configurations, such as where portion(s) of device 102 are external to the patient, the electrode(s) coupling device 102 to heart 104 may include a skin surface electrode external to the patient. The electrodes may be associated with the heart for bipolar (i.e., two electrodes that are relatively close together) or for unipolar (i.e., two electrodes that are farther apart) signal sensing or therapy energy delivery (e.g., pacing pulse or shocks).
In the illustrative example of FIG. 1, programmer 106 includes a controller or processor that is capable of sequencing through various control states such as, for example, by using a digital microprocessor having executable instructions stored in an associated instruction memory circuit, a microsequencer, or a state machine. The controller or processor typically also includes, or is coupled to, a memory circuit for storing data. Programmer 106 also includes a user input/output interface 110, which includes a display 112. Among other things, a physician or other caregiver (or, in certain cases, the patient) uses user interface 110 for programming therapy and other operative parameters of device 102. As discussed above, such parameters are often subject to a complex set of rules governing how they interact with each other. This often makes the task of programming a consistent set of values for the various parameters extremely difficult for the user. Moreover, because some of these parameters are used for tailoring the particulars of therapy being delivered to the subject, the programming of appropriate values for these parameters is often very important to providing proper therapy to the subject. For these and other reasons, the present inventors have recognized a need for improved techniques for assisting a physician, caregiver, or other user in programming one or more parameters of an implantable cardiac rhythm management device.
FIG. 2 is a screen shot of a portion of display 112, including, by way of example, but not by way of limitation, one embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of device 102. In this example, display 112 includes a graphical indication of the at least one parameter to be programmed. In FIG. 2, three cardiac rhythm management therapy parameters are presented: a post-ventricular atrial refractory period (PVARP), a atrio-ventricular (AV) delay, and a maximum tracking rate (MTR). These particular parameters are presented by way of example only, and not by way of limitation. The PVARP defines the length of time (“refractory period”) after a paced or sensed ventricular contraction during which any atrial contraction, sensed from an atrial electrode, will be ignored. The AV delay defines a timeout after a paced or sensed atrial contraction after which a ventricular pacing pulse will be delivered if no ventricular contraction has been sensed during the AV delay. The MTR defines a time interval corresponding to a maximum pacing rate, wherein information received from a physiologic sensor is only allowed to drive the patient's pacing rate up to that MTR rate limit.
In this particular example, the graphical indication is presented in the form of a bar graph icon, such as PVARP icon 200, AV delay icon 202, and MTR icon 204. The length of the bar graph icon represents the programmably adjustable value of the corresponding parameter. In the example of FIG. 2, these values are expressed in terms of time intervals, with an optional corresponding indication of rate provided to assist the user in translating between time interval and rate. For example, in FIG. 2, the value represented by PVARP icon 200 is 300 milliseconds, the value represented by AV Delay icon 202 is 290 milliseconds, and the value represented by MTR icon 204 is 500 milliseconds. Additionally, MTR icon 204 also presents the corresponding represented value expressed in terms of rate, i.e., 120 beats per minute (bpm).
In the example of FIG. 2, the parameter icons are “draggable” (e.g., using a computer mouse cursor on display 112, or using a finger on a touch-screen display 112) to change the value of the parameter represented by the icon by dragging an edge of the bar graph parameter icon to increase or decrease its length. In FIG. 2, this is represented by triangles located at an edge of a bar graph icon; the triangles are pointing in opposite directions to indicate to the user that the length of the bar graph parameter icon can be increased or decreased to change the underlying parameter value.
In the example of FIG. 2, the parameter icons are presented in visual correspondence with one another to illustrate to the user a particular rule imposing a limitation on the value of at least one of the parameters. In the example of FIG. 2, the illustrated rule represents a relationship between the allowable time intervals of the PVARP, AV delay, and MTR parameters. More particularly, the rule requires that the sum of PVARP and AV delay not exceed the MTR. This is illustrated by presenting PVARP icon 200 and AV Delay icon 202 side-by-side such that their lengths are additively illustrated, and presenting MTR icon 204, in visual correspondence therewith, such as immediately below PVARP icon 200 and AV Delay icon 202. In this way, the sum of the lengths of PVARP icon 200 and AV Delay icon 202 can be visually compared to the limit imposed by the length of MTR icon 204.
In a further example, a graphical indication flags when the rule has been violated. In one example, a color of the icons and/or the background may change (e.g., from green to red) when a rule violation occurs. In yet a further example, a graphical corrective indication indicates how the rule violation can be corrected. In the example illustrated in FIG. 2, this corrective indication includes arrows 206 and 208. Arrow 206 indicates that the illustrated rule violation can be corrected by decreasing the values of one of PVARP and AV Delay, such that the sum of PVARP and AV Delay no longer exceeds the MTR. Arrow 208 indicates that the illustrated rule violation can alternatively be corrected by increasing the value of MTR such that it exceeds the sum of PVARP and AV Delay.
The rule-illustrative graphical indications, such as illustrated in FIG. 2, make it easier for the user to understand how to program one or more related parameters to particular values that do not violate the illustrated rule governing the relationship between the parameters. FIG. 2 also illustrates icons for organizing therapy and other operative parameters for selection and display by the user. As illustrative examples, FIG. 2 includes “Brady Parameters” icon 210A, “Tachy Parameters” icon 210B, and “Other Parameters” icon 210C. In operation, “clicking” on one of these icons using a mouse cursor triggers a rule-illustrative display of one or more corresponding parameters or, alternatively, a menu for selectively displaying one or more such rule-illustrative parameters.
FIG. 3 is a screen shot of an alternative portion of display 112, including, by way of example, but not by way of limitation, one embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of device 102. In the example of FIG. 3, display 112 illustrates all rules that are associated with at least one particular parameter being programmed. For example, in FIG. 3, the parameter being programmed in is PVARP, which, in one example, is divided into two sub-parameters, i.e., a minimum PVARP (“Min PVARP”) and a maximum PVARP (“Max PVARP”). FIG. 3 is intended to illustrate an example in which display 112 provides a graphical illustration of each rule governing PVARP (i.e., governing Min PVARP or governing Max PVARP). Although FIG. 3 presents an illustrative example of such rules, it is understood that all rules governing the parameter being programmed (e.g., PVARP) need not be displayed concurrently. For example, if the number of rules to be displayed exceeds the available screen space, display 112 provides a scrollbar or other user-accessible device for obtaining or selecting particular rules for display and/or programming.
In the example of FIG. 3, display 112 includes a bar graph Min PVARP icon 300 and a bar graph Max PVARP icon 302, the length of each indicating its value in milliseconds. As discussed above, the user can programmably adjust these values by “dragging” an edge of the Min PVARP icon 300 or the Max PVARP icon 302 to change its length, thereby increasing or decreasing the corresponding parameter value. In this example, display 112 includes four graphical rule indications 304A–D. Each graphical rule indication 304A–D graphically illustrates a rule involving the parameter being programmed (in this case PVARP, which comprises two sub-parameters Min PVARP and Max PVARP). As the user adjusts the length of Min PVARP icon 300 or Max PVARP icon 302, a corresponding length of the same sub-parameter is simultaneously changed in the applicable graphical rule indications 304A–D. This allows the user to visualize how changing a parameter is affected by all the rules related to that parameter. It further enables the user to visualize which rule is violated, if any, how close other rules are to being violated, which other parameters affect those rules, and how the values of those other parameters could be adjusted to avoid violation of one or more rules.
For example, graphical rule indication 304A indicates a rule in which the sum of a Minimum AV Delay (“Min AV Delay”) parameter and Min PVARP must not exceed the Maximum Tracking Rate Interval (MTRI). Graphical rule indication 304B indicates a rule in which the Min PVARP must not exceed ½ of the MTRI. Graphical rule indication 304C indicates a rule in which the sum of a maximum AV Delay (“Max AV Delay”) and Max PVARP must not exceed a Lower Rate Limit Interval (LRLI). Graphical rule indication 304D indicates a rule in which the sum of an Atrial Fibrillation Rate Interval (AFRI), a Left Ventricular Offset (LV Offset), and a 50 millisecond constant must not exceed a difference between LRLI and a margin parameter (“Delta”).
In the example of FIG. 4, the user has dragged the edge of the Min PVARP icon 300 to increase its value from 180 milliseconds to 220 milliseconds. As a result, the second illustrated rule (indicated by graphical rule indication 304B) has been violated since Min PVARP now exceeds MTRI/2. In response to this rule violation, the background of graphical rule indication 304B has changed shading or color (e.g., from white to yellow).
In the example of FIG. 5, the user has dragged the edge of the Max PVARP icon 302 to increase its value from 260 milliseconds to 350 milliseconds. As a result, the fourth illustrated rule (indicated by graphical rule indication 304D) has been violated since the sum of AFRI, LV Offset, a 50 millisecond constant, and Max PVARP now exceeds the limit imposed by LRLI—Delta, illustrated immediately below that sum. In response to this rule violation, the background of graphical rule indication 304D has changed shading or color (e.g., from white to red). In one example, different colors of changed shading in response to a rule violation convey different information. For example, a changed background shading from white to yellow may indicate violation of a recommended rule, whereas a changed background from white to red may indicate violation of an absolute rule. In one example, a user is allowed to program a combination of parameter values that violates a recommended rule, but is not allowed to program a combination of parameter values that violates an absolute rule.
In FIG. 3, display 112 also includes a “Rationale” button 306A–D corresponding to each graphical rule indication 304A–D. In response to the user clicking on the appropriate “Rationale” button, display 112 provides a box 600 that provides further textual or graphical information relating to that graphically-illustrated rule, as illustrated in the example of FIG. 6, for which the user has selected “Rationale” button 306D. By clicking on the “OK” button of box 600, display 112 discontinues its display of box 600.
FIG. 7 is a screen shot of a portion of a display, similar to FIG. 3, but including a graphical parameter selector icon 700. Parameter selector icon 700 allows the user to select between different (related or unrelated) parameters, triggering a corresponding display of graphical illustrations of one or more rules associated with the selected parameter. In the example of FIG. 7, parameter selector icon 700 includes a button menu for selecting either “Dynamic PVARP” or “Fixed PVARP.” In this example, the parameters “Dynamic PVARP” and “Fixed PVARP” are related in the sense that both apply to a PVARP, as discussed above. Unlike “Fixed PVARP,” the value of the “Dynamic PVARP” parameter is a function of the patient's underlying heart rate and is, therefore, subject to an at least partially different set of rules governing the PVARP parameter. Patient selector icon 700 triggers display of graphical indications of the appropriate set of rules corresponding to the one of “Dynamic PVARP” and “Fixed PVARP” selector, and allows graphical adjustment of one or more parameters affected by the displayed rules.
FIGS. 8A and 8B are screen shots of alternative portions of a display 112 that includes, by way of example, but not by way of limitation, another embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of a device 102 based on a value of a different parameter. FIG. 8A illustrates an example of a display 112 that includes at least two parameter icons. In this example, a first parameter icon 800 indicates graphically whether a binary-valued parameter, “Feature A,” is on or off. A second parameter icon 802 indicates graphically a value of a range parameter, “Parameter B.” In this example, icon 802 is a bar graph having a length that graphically indicates the value of “Parameter B” (the value is also indicated textually on icon 802). Icon 802 also allows the value of “Parameter B” to be adjusted by dragging an edge of the bar graph icon 802, such as discussed above. The displayed length of the bar graph icon 802 represents graphically to the user the value to which “Parameter B” is being programmed; in this example, the changing value is also indicated textually on bar graph icon 802.
FIG. 8A illustrates an example of a rule being violated. In one example, the rule violation triggers the illustrated textual description of the rule violation. In this case, when “Feature A” is “on,” then the range of values to which “Parameter B” can be programmed is limited. Alternatively (or additionally), the occurrence of the rule violation is flagged graphically, such as by changing a background color, as discussed above. The example illustrated in FIG. 8A also includes a displayed corrective action indicator 804. In this example, the corrective action indicator 804 includes an arrow indicating the direction that the edge of bar graph icon 802 should be dragged to change the underlying value of “Parameter B” such that the rule is no longer violated; such a result is illustrated in FIG. 8B.
FIGS. 9A and 9B are screen shots of alternative portions of a display 112, including, by way of example, but not by way of limitation, another embodiment of a rule-illustrative system and method for programmably adjusting at least one parameter of a device 102. The example of FIG. 9A illustrates three parameter icons 900A, 900B, and 900C, respectively corresponding to the binary-valued (e.g., “on/off”) parameters “Feature A,” “Feature B,” and “Feature C.” In this example, a rule governing these three parameters indicates that only one of these “Feature A,” “Feature B,” and “Feature C” can be on at one time. Therefore, in this example, the three parameter icons 900A–C are presented in visual correspondence with each other, so that the user can easily determine how to resolve an underlying rule violation. In one example, the parameter icons 900A–C are displayed as user-selectable “buttons” that can be selected to toggle the value of the particular parameter corresponding to the icon between “on” and “off” to correct the rule violation; such a result is illustrated by the example of FIG. 9B. Moreover, in one example, a textual description of the underlying rule or rule violation is presented. In another example, a graphical indication flags rule violation, such as by a change in background color or other technique, as discussed above. In yet a further example, a graphical indication of corrective action is presented, such as, in this example, arrows pointing to the more than one feature that is “on” simultaneously in violation of the rule.
It is to be understood that the above description is intended to be illustrative, and not restrictive. For example, the above-discussed examples may be used in combination with each other. Many other embodiments will be apparent to those of skill in the art upon reviewing the above description. The scope of the invention should, therefore, be determined with reference to the appended claims, along with the full scope of equivalents to which such claims are entitled. Moreover, in the following claims, the terms “first,” “second,” “third,” etc. are used merely as labels, and are not intended to impose numeric requirements on their objects.

Claims (29)

1. A system comprising:
a programmer device, including a communication circuit configured to be communicatively coupled to an implantable cardiac rhythm management (CRM) device, and including a user interface configured to program a plurality of parameters used by the CRM device, the user interface configured to interactively display, during a programming of at least one of the parameters:
a graphical indication of a changing value of at least one of the parameters as at least one of the parameters is being programmed graphically; and
a graphical illustration of how a rule constrains the value of the at least one of the parameters being programmed graphically.
2. The system of claim 1, in which the user interface is configured to interactively flag a violation of the rule constraining the at least one of the parameters being programmed as the value of the at least one of the parameters being programmed is being changed such that it violates the rule constraining the at least one of the parameters being programmed.
3. The system of claim 2, in which the user interface is configured to provide a corrective indication, if a violation of the rule is flagged, the corrective indication informing a user how the value of at least one parameter included by the rule should be changed to correct the violation of the rule.
4. The system of claim 1, in which the graphical indication of the changing value of the at least one parameter being programmed includes a draggable bar graph icon having a bar length indicative of the value of the at least one parameter being programmed.
5. The system of claim 4, in which the graphical indication of the rule includes a bar graph icon presented in visual correspondence with the graphical indication of the changing value of the at least one parameter being programmed.
6. The system of claim 1, in which the rule constraining the value of the at least one parameter being programmed includes a limit that constrains a combination of the value of the at least one parameter being programmed and a value of at least one other parameter.
7. The system of claim 1, in which the user interface includes a graphical indication of a changing value of the at least one parameter as it is being programmed together with a graphical indication of a plurality of rules constraining the value of the at least one parameter being programmed.
8. The system of claim 1, in which the user interface includes a graphical indication of a changing value of the at least one parameter as it is being programmed together with a graphical indication of every rule constraining the value of the at least one parameter being programmed.
9. The system of claim 1, in which the graphical indication of the rule constraining the value of the at least one parameter being programmed includes an accompanying icon that, when selected, triggers a textual display of a rationale underlying the rule constraining the value of the at least one parameter being programmed.
10. A system comprising:
a programmer device, including a communication circuit configured to be communicatively coupled to an implantable cardiac rhythm management (CRM) device, and including a user interface configured to program a plurality of parameters used by the CRM device, the user interface interactively displaying, during a programming of at least one parameter, at least one graphical bar graph indication of a changing time interval value of the at least one parameter as it is being programmed together with a corresponding graphical illustration of how every applicable rule constrains the value of the at least one parameter being programmed.
11. The system of claim 10, in which at least one rule constraining the value of the at least one parameter being programmed includes a limit that constrains a combination of the value of the at least one parameter being programmed and a value of at least one other parameter.
12. A method of programming an implantable cardiac rhythm management device, the method comprising:
providing to a user a graphical indication of a value of a first parameter being programmed graphically by the user, the graphical indication being modifiable by the user to program the value of the first parameter; and
providing to the user a graphical illustration of how a rule constrains the value of the first parameter being programmed graphically by the user.
13. The method of claim 12, further comprising flagging a violation of the rule constraining the first parameter being programmed as the value of the first parameter being programmed is being changed such that it violates the rule constraining the first parameter being programmed.
14. The method of claim 13, further comprising providing a corrective indication, upon the flagging the violation of the rule, the corrective indication informing a user how the value of the first parameter should be changed to correct the violation of the rule.
15. The method of claim 12, in which the providing to the user the graphical indication of the value of the first parameter being programmed includes providing a draggable bar graph icon having a bar length indicative of the value of the first parameter.
16. The method of claim 15, in which the providing to the user the graphical indication of the rule includes providing a bar graph icon presented in visual correspondence with the graphical indication of the value of the first parameter.
17. The method of claim 12, in which the providing to the user the graphical indication of the rule includes providing a limit that constrains a combination of the value of the first parameter being programmed and a value of at least one other parameter.
18. The method of claim 12, further comprising providing to the user a graphical indication of a changing value of the first parameter as it is being programmed together with a graphical indication of a plurality of rules constraining the value of the first parameter being programmed.
19. The method of claim 12, further comprising providing to the user a graphical indication of a changing value of the first parameter as it is being programmed together with a graphical indication of every rule constraining the value of the first parameter being programmed.
20. The method of claim 12, in which the providing to the user a graphical indication of the rule constraining the value of the first parameter being programmed further comprises providing an accompanying icon that, when selected by the user, triggers a textual display of the rationale underlying the rule constraining the value of the first parameter being programmed.
21. A system comprising:
a programmer device, including a communication circuit configured to be communicatively coupled to an implantable cardiac rhythm management (CRM) device, and including a user interface configured to program a plurality of parameters used by the CRM device, the user interface interactively displaying together, during a programming of at least one parameter, a plurality of graphical icons corresponding to respective binary-valued parameters and an indication of how a rule limits the number of the parameters that can concurrently be programmed to a particular binary-valued state.
22. The system of claim 21, in which the user interface is configured to interactively graphically flag a violation of the rule.
23. The system of claim 22, in which the user interface is configured to provide a corrective indication, if a violation of the rule is flagged, the corrective indication informing a user how the value of at least one parameter governed by the rule should be changed to correct the violation of the rule.
24. A method of programming an implantable cardiac rhythm management device, the method comprising:
displaying to a user, in visual correspondence, graphical icons corresponding to binary-valued parameters and an indication of how a rule limits the number of the parameters that can concurrently be programmed to a particular binary-valued state, each icon being selectable to program the parameter corresponding to that icon; and
receiving from the user a selection of one of the icons to program the corresponding parameter to a particular binary-valued state.
25. The method of claim 24, further comprising graphically flagging a violation of the rule.
26. The method of claim 24, further comprising providing a graphical corrective action indication, if a violation of the rule exists, the corrective indication informing a user how to correct the violation of the rule.
27. A system comprising:
a programmer device, including a communication circuit configured to be communicatively coupled to an implantable cardiac rhythm management (CRM) device, and including a user interface configured to program a plurality of parameters used by the CRM device, the user interface configured to interactively display, during a programming of at least one of the parameters:
means for graphically changing value of at least one of the parameters as at least one of the parameters is being programmed graphically; and
a graphical illustration of how a rule constrains the value of the at least one of the parameters being programmed graphically.
28. The system of claim 27, in which the user interface is configured to interactively flag a violation of the rule constraining the at least one of the parameters being programmed as the value of the at least one of the parameters being programmed is being changed such that it violates the rule constraining the at least one of the parameters being programmed.
29. The system of claim 28, in which the user interface is configured to provide a corrective indication, if a violation of the rule is flagged, the corrective indication informing a user how the value of at least one parameter included by the rule should be changed to correct the violation of the rule.
US10/310,702 2002-12-05 2002-12-05 Cardiac rhythm management systems and methods for rule-illustrative parameter entry Expired - Lifetime US7191006B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US10/310,702 US7191006B2 (en) 2002-12-05 2002-12-05 Cardiac rhythm management systems and methods for rule-illustrative parameter entry

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/310,702 US7191006B2 (en) 2002-12-05 2002-12-05 Cardiac rhythm management systems and methods for rule-illustrative parameter entry

Publications (2)

Publication Number Publication Date
US20040111131A1 US20040111131A1 (en) 2004-06-10
US7191006B2 true US7191006B2 (en) 2007-03-13

Family

ID=32468095

Family Applications (1)

Application Number Title Priority Date Filing Date
US10/310,702 Expired - Lifetime US7191006B2 (en) 2002-12-05 2002-12-05 Cardiac rhythm management systems and methods for rule-illustrative parameter entry

Country Status (1)

Country Link
US (1) US7191006B2 (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060031094A1 (en) * 2004-08-06 2006-02-09 Medtronic Minimed, Inc. Medical data management system and process
US20060041288A1 (en) * 2004-08-18 2006-02-23 Medtronic, Inc. Conversational interface for programmable implantable medical device
US20080126968A1 (en) * 2006-04-27 2008-05-29 Jeff West Medical device user interface automatically resolving interaction between programmable parameters
US20090187426A1 (en) * 2006-05-31 2009-07-23 Kerstna Juergen Implantable medical device system and method for adapting functions of the clinician's workstation thereof
US20100069991A1 (en) * 2008-09-15 2010-03-18 Cardiac Pacemakers, Inc. Systems and methods for highly safe adjustment of device parameters
US20100318155A1 (en) * 2009-05-14 2010-12-16 Cardiac Pacemakers, Inc. Systems and methods for programming implantable medical devices
US8121689B2 (en) 2007-10-01 2012-02-21 Cardiac Pacemakers, Inc. Proactive interactive limits override for implantable medical device user interface

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6321117B1 (en) 1999-08-20 2001-11-20 Cardiac Pacemakers, Inc. Change log for implantable medical device
US6289248B1 (en) * 1999-08-20 2001-09-11 Cardiac Pacemakers, Inc. System and method for detecting and displaying parameter interactions
US7894908B2 (en) * 2003-04-02 2011-02-22 Medtronic, Inc. Neurostimulation therapy optimization based on a rated session log
US7489970B2 (en) * 2003-04-02 2009-02-10 Medtronic, Inc. Management of neurostimulation therapy using parameter sets
US7505815B2 (en) * 2003-04-02 2009-03-17 Medtronic, Inc. Neurostimulation therapy usage diagnostics
US7548786B2 (en) * 2003-04-02 2009-06-16 Medtronic, Inc. Library for management of neurostimulation therapy programs
US7751892B2 (en) 2003-05-07 2010-07-06 Cardiac Pacemakers, Inc. Implantable medical device programming apparatus having a graphical user interface
US7272444B2 (en) * 2003-05-07 2007-09-18 Cardiac Pacemakers, Inc. Medical device interface system with automatic rate threshold adjustment
US7333856B1 (en) * 2004-05-17 2008-02-19 Pacesetter, Inc. Method and system to graphically display programming parameters for multi-chamber devices
US7819909B2 (en) * 2004-07-20 2010-10-26 Medtronic, Inc. Therapy programming guidance based on stored programming history
GB2421135A (en) 2004-12-09 2006-06-14 Sony Uk Ltd User resizable video display of catalogue entries
US7747330B2 (en) * 2006-03-09 2010-06-29 Medtronic, Inc. Global parameter adjustment for multiple stimulation programs
US8380300B2 (en) * 2006-04-28 2013-02-19 Medtronic, Inc. Efficacy visualization
US8306624B2 (en) * 2006-04-28 2012-11-06 Medtronic, Inc. Patient-individualized efficacy rating
US9968732B2 (en) * 2008-07-14 2018-05-15 Medtronic, Inc. Interface for implantable medical device programming
WO2016044169A1 (en) * 2014-09-15 2016-03-24 Boston Scientific Neuromodulation Corporation Graphical user interface for programming neurostimulation pulse patterns
AU2015343483B2 (en) 2014-11-04 2018-03-01 Boston Scientific Neuromodulation Corporation Method and apparatus for programming complex neurostimulation patterns
CN107921255B (en) 2015-07-30 2021-02-26 波士顿科学神经调制公司 User interface for custom-patterned electrical stimulation
WO2017066187A1 (en) 2015-10-15 2017-04-20 Boston Scientific Neuromodulation Corporation User interface for neurostimulation waveform composition

Citations (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4006737A (en) 1974-01-04 1977-02-08 Del Mar Engineering Laboratories Electrocardiographic computer
US4090505A (en) * 1976-06-01 1978-05-23 Marquette Electronics, Inc. Electrocardiographic recording method and means
US4166470A (en) 1977-10-17 1979-09-04 Medtronic, Inc. Externally controlled and powered cardiac stimulating apparatus
US4172459A (en) 1977-10-17 1979-10-30 Medtronic, Inc. Cardiac monitoring apparatus and monitor
US4187854A (en) 1977-10-17 1980-02-12 Medtronic, Inc. Implantable demand pacemaker and monitor
US4197850A (en) 1978-11-03 1980-04-15 Pacesetter Systems, Inc. Implantable human tissue stimulator with memory protect means
US4208008A (en) 1978-11-06 1980-06-17 Medtronic, Inc. Pacing generator programming apparatus including error detecting means
US4232679A (en) 1977-01-26 1980-11-11 Pacesetter Systems, Inc. Programmable human tissue stimulator
US4236524A (en) 1978-11-06 1980-12-02 Medtronic, Inc. Program testing apparatus
US4316249A (en) 1979-09-28 1982-02-16 Hittman Corporation Automatic high speed Holter scanning system
US4323074A (en) 1979-03-12 1982-04-06 Medtronic, Inc. Pacemaker programming apparatus utilizing a computer system with simplified data input
US4336810A (en) 1980-09-30 1982-06-29 Del Mar Avionics Method and apparatus for arrhythmia analysis of ECG recordings
US4407288A (en) 1981-02-18 1983-10-04 Mieczyslaw Mirowski Implantable heart stimulator and stimulation method
US4432360A (en) 1981-07-06 1984-02-21 Cordis Corporation Interactive programmer for biomedical implantable devices
US4509530A (en) 1983-12-27 1985-04-09 International Business Machines Corporation System for plotting a miniature ECG
US4529401A (en) 1982-01-11 1985-07-16 Cardiac Pacemakers, Inc. Ambulatory infusion pump having programmable parameters
US4549552A (en) 1981-03-06 1985-10-29 Siemens Gammasonics, Inc. Heart sound detector and cardiac cycle data are combined for diagnostic reliability
US4680708A (en) 1984-03-20 1987-07-14 Washington University Method and apparatus for analyzing electrocardiographic signals
US4726380A (en) 1983-10-17 1988-02-23 Telectronics, N.V. Implantable cardiac pacer with discontinuous microprocessor, programmable antitachycardia mechanisms and patient data telemetry
US4809697A (en) 1987-10-14 1989-03-07 Siemens-Pacesetter, Inc. Interactive programming and diagnostic system for use with implantable pacemaker
US4825869A (en) 1987-09-28 1989-05-02 Telectronics N.V. System for automatically performing a clinical assessment of an implanted pacer based on information that is telemetrically received
US4947857A (en) 1989-02-01 1990-08-14 Corazonix Corporation Method and apparatus for analyzing and interpreting electrocardiograms using spectro-temporal mapping
US4958632A (en) 1978-07-20 1990-09-25 Medtronic, Inc. Adaptable, digital computer controlled cardiac pacemaker
US4969460A (en) * 1988-03-25 1990-11-13 Telectronics N.V. Pacemaker with improved automatic output regulation
US4974598A (en) 1988-04-22 1990-12-04 Heart Map, Inc. EKG system and method using statistical analysis of heartbeats and topographic mapping of body surface potentials
US4979506A (en) * 1989-08-08 1990-12-25 Siemens-Pacesetter, Inc. Self-test system and method for external programming device
US4989610A (en) 1987-11-16 1991-02-05 Spacelabs, Inc. Method and system of ECG data review and analysis
US5000189A (en) 1989-11-15 1991-03-19 Regents Of The University Of Michigan Method and system for monitoring electrocardiographic signals and detecting a pathological cardiac arrhythmia such as ventricular tachycardia
US5012814A (en) 1989-11-09 1991-05-07 Instromedix, Inc. Implantable-defibrillator pulse detection-triggered ECG monitoring method and apparatus
US5027824A (en) 1989-12-01 1991-07-02 Edmond Dougherty Method and apparatus for detecting, analyzing and recording cardiac rhythm disturbances
US5046504A (en) 1989-02-01 1991-09-10 Corazonix Corporation Method and apparatus for analyzing and interpreting electrocardiograms using spectro-temporal mapping
US5047930A (en) 1987-06-26 1991-09-10 Nicolet Instrument Corporation Method and system for analysis of long term physiological polygraphic recordings
US5050612A (en) 1989-09-12 1991-09-24 Matsumura Kenneth N Device for computer-assisted monitoring of the body
US5052395A (en) 1987-11-16 1991-10-01 Waters Instruments, Inc. Non-invasive ultrasonic pulse doppler cardiac output monitor
US5107850A (en) 1990-11-02 1992-04-28 Cardiac Pacemakers, Inc. Method and apparatus for classifying and treating cardiac arrhythmias based on atrial and ventricular activity
US5113869A (en) 1990-08-21 1992-05-19 Telectronics Pacing Systems, Inc. Implantable ambulatory electrocardiogram monitor
US5159926A (en) * 1989-08-28 1992-11-03 Siemens Aktiengesellschaft Medical stimulation and/or monitoring device interacting with the body of a patient based upon selectable parameter set
US5184614A (en) 1990-10-19 1993-02-09 Telectronics Pacing Systems, Inc. Implantable haemodynamically responsive cardioverting/defibrillating pacemaker
US5193550A (en) 1990-11-30 1993-03-16 Medtronic, Inc. Method and apparatus for discriminating among normal and pathological tachyarrhythmias
US5215083A (en) 1991-10-07 1993-06-01 Telectronics Pacing Systems, Inc. Apparatus and method for arrhythmia induction in arrhythmia control system
US5224475A (en) 1991-11-20 1993-07-06 Medtronic, Inc. Method and apparatus for termination of ventricular tachycardia and ventricular fibrillation
US5273049A (en) 1992-04-09 1993-12-28 Telectronics Pacing Systems, Inc. Detection of cardiac arrhythmias using template matching by signature analysis
US5292341A (en) 1992-03-02 1994-03-08 Siemens Pacesetter, Inc. Method and system for determining and automatically adjusting the sensor parameters of a rate-responsive pacemaker
US5309919A (en) 1992-03-02 1994-05-10 Siemens Pacesetter, Inc. Method and system for recording, reporting, and displaying the distribution of pacing events over time and for using same to optimize programming
US5312448A (en) 1989-09-07 1994-05-17 Siemens Aktiengesellschaft Medical appliance for stimulating tissue contractions
US5311873A (en) 1992-08-28 1994-05-17 Ecole Polytechnique Comparative analysis of body surface potential distribution during cardiac pacing
US5311874A (en) 1992-05-18 1994-05-17 Cardiac Pacemakers, Inc. Method for tachycardia discrimination
US5315512A (en) 1989-09-01 1994-05-24 Montefiore Medical Center Apparatus and method for generating image representations of a body utilizing an ultrasonic imaging subsystem and a three-dimensional digitizer subsystem
US5341811A (en) 1991-03-26 1994-08-30 Allegheny-Singer Research Institute Method and apparatus for observation of ventricular late potentials
US5342402A (en) 1993-01-29 1994-08-30 Medtronic, Inc. Method and apparatus for detection and treatment of tachycardia and fibrillation
US5360437A (en) 1991-10-31 1994-11-01 Medtronic, Inc. Implantable medical device with flexible hardware platform
US5371851A (en) * 1989-04-26 1994-12-06 Credence Systems Corporation Graphical data base editor
US5379776A (en) 1993-04-01 1995-01-10 Telectronics Pacing Systems, Inc. Heart rhythm classification method, and implantable dual chamber cardioverter/defibrillator employing the same
US5404877A (en) 1993-06-04 1995-04-11 Telectronics Pacing Systems, Inc. Leadless implantable sensor assembly and a cardiac emergency warning alarm
US5411528A (en) 1992-11-19 1995-05-02 Pacesetter, Inc. Electrically programmable polarity connector for an implantable body tissue stimulator
US5421830A (en) * 1993-08-27 1995-06-06 Pacesetter, Inc. Programming system having means for recording and analyzing a patient's cardiac signal
US5423871A (en) 1993-01-29 1995-06-13 Pacesetter Ab Method and device for monitoring electrodes of electrical heart stimulators
US5431691A (en) 1992-03-02 1995-07-11 Siemens Pacesetter, Inc. Method and system for recording and displaying a sequential series of pacing events
US5433198A (en) 1993-03-11 1995-07-18 Desai; Jawahar M. Apparatus and method for cardiac ablation
US5447164A (en) * 1993-11-08 1995-09-05 Hewlett-Packard Company Interactive medical information display system and method for displaying user-definable patient events
US5458623A (en) 1994-03-04 1995-10-17 Telectronics Pacing Systems, Inc. Automatic atrial pacing threshold determination utilizing an external programmer and a surface electrogram
US5464433A (en) 1994-06-14 1995-11-07 Incontrol, Inc. Atrial defibrillator and method providing dual reset of an interval timer
US5480422A (en) 1993-07-20 1996-01-02 Biosense, Inc. Apparatus for treating cardiac arrhythmias
US5496351A (en) 1993-10-05 1996-03-05 Sorin Biomedica S.P.A. Device for determining myocardial function and corresponding procedure
US5507786A (en) 1994-04-14 1996-04-16 Pacesetter, Inc. System and method for measuring and storing parametric data pertaining to operating characteristics of an implantable medical device
US5513645A (en) 1993-11-17 1996-05-07 Ela Medical S.A. Holter functions with a zoom feature
US5523942A (en) 1994-03-31 1996-06-04 New England Mutual Life Insurance Company Design grid for inputting insurance and investment product information in a computer system
US5535753A (en) 1994-10-04 1996-07-16 Rutgers University Apparatus and methods for the noninvasive measurement of cardiovascular system parameters
US5549646A (en) 1994-12-06 1996-08-27 Pacesetter, Inc. Periodic electrical lead intergrity testing system and method for implantable cardiac stimulating devices
US5549654A (en) 1994-04-15 1996-08-27 Medtronic, Inc. Interactive interpretation of event markers in body-implantable medical device
US5555888A (en) 1995-02-27 1996-09-17 Brewer; James E. Method for automatic, adaptive, active facilitation to access myocardial electrical instability
US5578063A (en) 1995-10-19 1996-11-26 Incontrol, Inc. Implantable atrial defibrillator and system having multiple channel electrogram telemetry and method
US5584298A (en) * 1993-10-25 1996-12-17 Kabal; John Noninvasive hemodynamic analyzer alterable to a continuous invasive hemodynamic monitor
US5603331A (en) 1996-02-12 1997-02-18 Cardiac Pacemakers, Inc. Data logging system for implantable cardiac device
US5607460A (en) * 1996-03-15 1997-03-04 Angeion Corporation Physician interface expert system for programming implantable arrythmia treatment devices
US5609612A (en) 1993-10-05 1997-03-11 Sorin Biomedica Cardio S.P.A. Device for determining myocardial function and corresponding procedure and method
US5613495A (en) 1991-12-26 1997-03-25 Instromedix, Inc. High functional density cardiac monitoring system for captured windowed ECG data
US5620472A (en) 1995-01-12 1997-04-15 Pacesetter, Inc. Apparatus and method for dynamically interpreting and displaying a real-time telemetry link
US5620474A (en) 1995-04-24 1997-04-15 Vitatron Medical, B.V. System and method for determining indicated pacemaker replacement time based upon battery impedance measurement
US5620471A (en) 1995-06-16 1997-04-15 Pacesetter, Inc. System and method for discriminating between atrial and ventricular arrhythmias and for applying cardiac therapy therefor
US5626620A (en) 1995-02-21 1997-05-06 Medtronic, Inc. Dual chamber pacing system and method with continual adjustment of the AV escape interval so as to maintain optimized ventricular pacing for treating cardiomyopathy
US5626623A (en) 1996-04-30 1997-05-06 Medtronic, Inc. Method and apparatus for optimizing pacemaker AV delay
US5628321A (en) 1995-12-18 1997-05-13 Diasonics Ultrasound, Inc. Processing velocity information in an ultrasonic system
US5643255A (en) 1994-12-12 1997-07-01 Hicor, Inc. Steerable catheter with rotatable tip electrode and method of use
US5674249A (en) 1996-05-02 1997-10-07 Incontrol, Inc. Atrial defibrillation system having a portable communication device
US5682489A (en) * 1991-06-04 1997-10-28 Digital Equipment Corporation, Inc. Method and device for monitoring, manipulating, and viewing system information
US5683431A (en) 1996-03-27 1997-11-04 Medtronic, Inc. Verification of capture by sensing evoked response across cardioversion electrodes
US5687737A (en) 1992-10-09 1997-11-18 Washington University Computerized three-dimensional cardiac mapping with interactive visual displays
US5697959A (en) 1996-01-11 1997-12-16 Pacesetter, Inc. Method and system for analyzing and displaying complex pacing event records
US5713366A (en) 1996-09-16 1998-02-03 Sulzer Intermedics Inc. Method and apparatus for dual chamber cardiac analysis
US5713937A (en) * 1995-11-07 1998-02-03 Pacesetter, Inc. Pacemaker programmer menu with selectable real or simulated implant data graphics
US5716383A (en) 1996-02-28 1998-02-10 Medtronic, Inc. Dual chamber pacing system and method with continual adjustment of the AV escape interval so as to maintain optimized ventricular pacing for treating cardiomyopathy
US5716384A (en) 1996-07-08 1998-02-10 Pacesetter, Inc. Method and system for organizing, viewing and manipulating information in implantable device programmer
US5716382A (en) 1995-08-02 1998-02-10 Pacesetter, Inc. Programmer for an implantable cardiac stimulating device
US5722999A (en) 1995-08-02 1998-03-03 Pacesetter, Inc. System and method for storing and displaying historical medical data measured by an implantable medical device
US5725559A (en) 1996-05-16 1998-03-10 Intermedics Inc. Programmably upgradable implantable medical device
US5724985A (en) 1995-08-02 1998-03-10 Pacesetter, Inc. User interface for an implantable medical device using an integrated digitizer display screen
US5743268A (en) 1993-10-25 1998-04-28 Kabal; John Noninvasive hemodynamic analyzer alterable to a continuous invasive hemodynamic monitor
US5749900A (en) 1995-12-11 1998-05-12 Sulzer Intermedics Inc. Implantable medical device responsive to heart rate variability analysis
US5749907A (en) 1997-02-18 1998-05-12 Pacesetter, Inc. System and method for identifying and displaying medical data which violate programmable alarm conditions
US5755736A (en) 1996-05-14 1998-05-26 Medtronic, Inc. Prioritized rule based method and apparatus for diagnosis and treatment of arrhythmias
US5755742A (en) 1996-11-05 1998-05-26 Medtronic, Inc. Cardioversion/defibrillation lead impedance measurement system
US5759199A (en) 1995-08-02 1998-06-02 Pacesetter, Inc. System and method for ambulatory monitoring and programming of an implantable medical device
US5891178A (en) * 1996-05-14 1999-04-06 Pacesetter, Inc. Programmer system and associated methods for rapidly evaluating and programming an implanted cardiac device
US5951484A (en) * 1997-08-01 1999-09-14 Harbinger Medical, Inc. Method of noninvasively determining a patient's susceptibility to arrhythmia
US5974341A (en) * 1997-12-22 1999-10-26 Pacesetter, Inc. Method and apparatus for detecting and displaying diagnostic information in conjunction with intracardiac electrograms and surface electrocardiograms
US6289244B1 (en) * 1999-08-20 2001-09-11 Cardiac Pacemakers, Inc. Self audit system
US6308100B1 (en) * 1997-12-22 2001-10-23 Pacesetter, Inc. Method and apparatus for displaying programming events detected by an implantable medical device
US6308102B1 (en) * 1999-09-29 2001-10-23 Stimsoft, Inc. Patient interactive neurostimulation system and method
US6418340B1 (en) * 1999-08-20 2002-07-09 Cardiac Pacemakers, Inc. Method and system for identifying and displaying groups of cardiac arrhythmic episodes
US6449504B1 (en) * 1999-08-20 2002-09-10 Cardiac Pacemakers, Inc. Arrhythmia display
US6842644B2 (en) * 2001-11-02 2005-01-11 Cardiac Pacemakers, Inc. User navigation and guidance during configuration and storage of parameters for medical device

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5924989A (en) * 1995-04-03 1999-07-20 Polz; Hans Method and device for capturing diagnostically acceptable three-dimensional ultrasound image data records
US6035233A (en) * 1995-12-11 2000-03-07 Intermedics Inc. Implantable medical device responsive to heart rate variability analysis
US5908392A (en) * 1996-03-13 1999-06-01 Pacesetter, Inc. System and method for recording and storing medical data in response to a programmable trigger
US5785660A (en) * 1996-03-28 1998-07-28 Pacesetter, Inc. Methods and apparatus for storing intracardiac electrograms
US6017307A (en) * 1996-05-31 2000-01-25 Vasocor, Inc. Integrated peripheral vascular diagnostic system and method therefor
US5876353A (en) * 1997-01-31 1999-03-02 Medtronic, Inc. Impedance monitor for discerning edema through evaluation of respiratory rate
US5772604A (en) * 1997-03-14 1998-06-30 Emory University Method, system and apparatus for determining prognosis in atrial fibrillation
US5891043A (en) * 1998-01-29 1999-04-06 Medtronic, Inc. Implantable medical device with automated last session identification
US5897577A (en) * 1997-11-07 1999-04-27 Medtronic, Inc. Pacing lead impedance monitoring circuit and method
US5891179A (en) * 1997-11-20 1999-04-06 Paceseter, Inc. Method and apparatus for monitoring and displaying lead impedance in real-time for an implantable medical device
US6016442A (en) * 1998-03-25 2000-01-18 Cardiac Pacemakers, Inc. System for displaying cardiac arrhythmia data
US6014581A (en) * 1998-03-26 2000-01-11 Ep Technologies, Inc. Interface for performing a diagnostic or therapeutic procedure on heart tissue with an electrode structure
US6045513A (en) * 1998-05-13 2000-04-04 Medtronic, Inc. Implantable medical device for tracking patient functional status
US6088618A (en) * 1998-07-07 2000-07-11 Vitatron Medical, B.V. Pacemaker system and method for providing manual display concurrent with pacemaker software modification
US6016447A (en) * 1998-10-27 2000-01-18 Medtronic, Inc. Pacemaker implant recognition
US6016448A (en) * 1998-10-27 2000-01-18 Medtronic, Inc. Multilevel ERI for implantable medical devices
US6240317B1 (en) * 1999-04-30 2001-05-29 Medtronic, Inc. Telemetry system for implantable medical devices
US6289248B1 (en) * 1999-08-20 2001-09-11 Cardiac Pacemakers, Inc. System and method for detecting and displaying parameter interactions
US6400981B1 (en) * 2000-06-21 2002-06-04 Biosense, Inc. Rapid mapping of electrical activity in the heart

Patent Citations (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4006737A (en) 1974-01-04 1977-02-08 Del Mar Engineering Laboratories Electrocardiographic computer
US4090505A (en) * 1976-06-01 1978-05-23 Marquette Electronics, Inc. Electrocardiographic recording method and means
US4232679A (en) 1977-01-26 1980-11-11 Pacesetter Systems, Inc. Programmable human tissue stimulator
US4232679B1 (en) 1977-01-26 1988-05-31
US4166470A (en) 1977-10-17 1979-09-04 Medtronic, Inc. Externally controlled and powered cardiac stimulating apparatus
US4172459A (en) 1977-10-17 1979-10-30 Medtronic, Inc. Cardiac monitoring apparatus and monitor
US4187854A (en) 1977-10-17 1980-02-12 Medtronic, Inc. Implantable demand pacemaker and monitor
US4958632A (en) 1978-07-20 1990-09-25 Medtronic, Inc. Adaptable, digital computer controlled cardiac pacemaker
US4197850A (en) 1978-11-03 1980-04-15 Pacesetter Systems, Inc. Implantable human tissue stimulator with memory protect means
US4236524A (en) 1978-11-06 1980-12-02 Medtronic, Inc. Program testing apparatus
US4208008A (en) 1978-11-06 1980-06-17 Medtronic, Inc. Pacing generator programming apparatus including error detecting means
US4323074A (en) 1979-03-12 1982-04-06 Medtronic, Inc. Pacemaker programming apparatus utilizing a computer system with simplified data input
US4316249A (en) 1979-09-28 1982-02-16 Hittman Corporation Automatic high speed Holter scanning system
US4336810A (en) 1980-09-30 1982-06-29 Del Mar Avionics Method and apparatus for arrhythmia analysis of ECG recordings
US4407288A (en) 1981-02-18 1983-10-04 Mieczyslaw Mirowski Implantable heart stimulator and stimulation method
US4407288B1 (en) 1981-02-18 2000-09-19 Mieczyslaw Mirowski Implantable heart stimulator and stimulation method
US4549552A (en) 1981-03-06 1985-10-29 Siemens Gammasonics, Inc. Heart sound detector and cardiac cycle data are combined for diagnostic reliability
US4432360A (en) 1981-07-06 1984-02-21 Cordis Corporation Interactive programmer for biomedical implantable devices
US4529401A (en) 1982-01-11 1985-07-16 Cardiac Pacemakers, Inc. Ambulatory infusion pump having programmable parameters
US4726380A (en) 1983-10-17 1988-02-23 Telectronics, N.V. Implantable cardiac pacer with discontinuous microprocessor, programmable antitachycardia mechanisms and patient data telemetry
US4509530A (en) 1983-12-27 1985-04-09 International Business Machines Corporation System for plotting a miniature ECG
US4680708A (en) 1984-03-20 1987-07-14 Washington University Method and apparatus for analyzing electrocardiographic signals
US5047930A (en) 1987-06-26 1991-09-10 Nicolet Instrument Corporation Method and system for analysis of long term physiological polygraphic recordings
US5299118A (en) 1987-06-26 1994-03-29 Nicolet Instrument Corporation Method and system for analysis of long term physiological polygraphic recordings
US4825869A (en) 1987-09-28 1989-05-02 Telectronics N.V. System for automatically performing a clinical assessment of an implanted pacer based on information that is telemetrically received
US4809697A (en) 1987-10-14 1989-03-07 Siemens-Pacesetter, Inc. Interactive programming and diagnostic system for use with implantable pacemaker
US4989610A (en) 1987-11-16 1991-02-05 Spacelabs, Inc. Method and system of ECG data review and analysis
US5052395A (en) 1987-11-16 1991-10-01 Waters Instruments, Inc. Non-invasive ultrasonic pulse doppler cardiac output monitor
US4969460A (en) * 1988-03-25 1990-11-13 Telectronics N.V. Pacemaker with improved automatic output regulation
US4974598A (en) 1988-04-22 1990-12-04 Heart Map, Inc. EKG system and method using statistical analysis of heartbeats and topographic mapping of body surface potentials
US4947857A (en) 1989-02-01 1990-08-14 Corazonix Corporation Method and apparatus for analyzing and interpreting electrocardiograms using spectro-temporal mapping
US5046504A (en) 1989-02-01 1991-09-10 Corazonix Corporation Method and apparatus for analyzing and interpreting electrocardiograms using spectro-temporal mapping
US5371851A (en) * 1989-04-26 1994-12-06 Credence Systems Corporation Graphical data base editor
US4979506A (en) * 1989-08-08 1990-12-25 Siemens-Pacesetter, Inc. Self-test system and method for external programming device
US5159926A (en) * 1989-08-28 1992-11-03 Siemens Aktiengesellschaft Medical stimulation and/or monitoring device interacting with the body of a patient based upon selectable parameter set
US5315512A (en) 1989-09-01 1994-05-24 Montefiore Medical Center Apparatus and method for generating image representations of a body utilizing an ultrasonic imaging subsystem and a three-dimensional digitizer subsystem
US5312448A (en) 1989-09-07 1994-05-17 Siemens Aktiengesellschaft Medical appliance for stimulating tissue contractions
US5050612A (en) 1989-09-12 1991-09-24 Matsumura Kenneth N Device for computer-assisted monitoring of the body
US5012814A (en) 1989-11-09 1991-05-07 Instromedix, Inc. Implantable-defibrillator pulse detection-triggered ECG monitoring method and apparatus
US5000189A (en) 1989-11-15 1991-03-19 Regents Of The University Of Michigan Method and system for monitoring electrocardiographic signals and detecting a pathological cardiac arrhythmia such as ventricular tachycardia
US5027824A (en) 1989-12-01 1991-07-02 Edmond Dougherty Method and apparatus for detecting, analyzing and recording cardiac rhythm disturbances
US5113869A (en) 1990-08-21 1992-05-19 Telectronics Pacing Systems, Inc. Implantable ambulatory electrocardiogram monitor
US5184614A (en) 1990-10-19 1993-02-09 Telectronics Pacing Systems, Inc. Implantable haemodynamically responsive cardioverting/defibrillating pacemaker
US5107850A (en) 1990-11-02 1992-04-28 Cardiac Pacemakers, Inc. Method and apparatus for classifying and treating cardiac arrhythmias based on atrial and ventricular activity
US5193550A (en) 1990-11-30 1993-03-16 Medtronic, Inc. Method and apparatus for discriminating among normal and pathological tachyarrhythmias
US5341811A (en) 1991-03-26 1994-08-30 Allegheny-Singer Research Institute Method and apparatus for observation of ventricular late potentials
US5682489A (en) * 1991-06-04 1997-10-28 Digital Equipment Corporation, Inc. Method and device for monitoring, manipulating, and viewing system information
US5215083A (en) 1991-10-07 1993-06-01 Telectronics Pacing Systems, Inc. Apparatus and method for arrhythmia induction in arrhythmia control system
US5360437A (en) 1991-10-31 1994-11-01 Medtronic, Inc. Implantable medical device with flexible hardware platform
US5344430A (en) 1991-11-20 1994-09-06 Medtronic, Inc. Method and apparatus for termination of ventricular tachycardia and ventricular fibrillation
US5224475A (en) 1991-11-20 1993-07-06 Medtronic, Inc. Method and apparatus for termination of ventricular tachycardia and ventricular fibrillation
US5613495A (en) 1991-12-26 1997-03-25 Instromedix, Inc. High functional density cardiac monitoring system for captured windowed ECG data
US5292341A (en) 1992-03-02 1994-03-08 Siemens Pacesetter, Inc. Method and system for determining and automatically adjusting the sensor parameters of a rate-responsive pacemaker
US5487755A (en) 1992-03-02 1996-01-30 Pacesetter, Inc. Methods for displaying a sequential series of pacing events
US5309919A (en) 1992-03-02 1994-05-10 Siemens Pacesetter, Inc. Method and system for recording, reporting, and displaying the distribution of pacing events over time and for using same to optimize programming
US5431691A (en) 1992-03-02 1995-07-11 Siemens Pacesetter, Inc. Method and system for recording and displaying a sequential series of pacing events
US5487754A (en) 1992-03-02 1996-01-30 Pacesetter, Inc. Method and apparatus for reporting and displaying a sequential series of pacing events
US5273049A (en) 1992-04-09 1993-12-28 Telectronics Pacing Systems, Inc. Detection of cardiac arrhythmias using template matching by signature analysis
US5311874A (en) 1992-05-18 1994-05-17 Cardiac Pacemakers, Inc. Method for tachycardia discrimination
US5311873A (en) 1992-08-28 1994-05-17 Ecole Polytechnique Comparative analysis of body surface potential distribution during cardiac pacing
US5687737A (en) 1992-10-09 1997-11-18 Washington University Computerized three-dimensional cardiac mapping with interactive visual displays
US5411528A (en) 1992-11-19 1995-05-02 Pacesetter, Inc. Electrically programmable polarity connector for an implantable body tissue stimulator
US5423871A (en) 1993-01-29 1995-06-13 Pacesetter Ab Method and device for monitoring electrodes of electrical heart stimulators
US5342402A (en) 1993-01-29 1994-08-30 Medtronic, Inc. Method and apparatus for detection and treatment of tachycardia and fibrillation
US5433198A (en) 1993-03-11 1995-07-18 Desai; Jawahar M. Apparatus and method for cardiac ablation
US5379776A (en) 1993-04-01 1995-01-10 Telectronics Pacing Systems, Inc. Heart rhythm classification method, and implantable dual chamber cardioverter/defibrillator employing the same
US5404877A (en) 1993-06-04 1995-04-11 Telectronics Pacing Systems, Inc. Leadless implantable sensor assembly and a cardiac emergency warning alarm
US5480422A (en) 1993-07-20 1996-01-02 Biosense, Inc. Apparatus for treating cardiac arrhythmias
US5421830A (en) * 1993-08-27 1995-06-06 Pacesetter, Inc. Programming system having means for recording and analyzing a patient's cardiac signal
US5693075A (en) 1993-10-05 1997-12-02 Sorin Biomedica S.P.A. Device for determining myocardial function and corresponding procedure
US5496351A (en) 1993-10-05 1996-03-05 Sorin Biomedica S.P.A. Device for determining myocardial function and corresponding procedure
US5609612A (en) 1993-10-05 1997-03-11 Sorin Biomedica Cardio S.P.A. Device for determining myocardial function and corresponding procedure and method
US5743268A (en) 1993-10-25 1998-04-28 Kabal; John Noninvasive hemodynamic analyzer alterable to a continuous invasive hemodynamic monitor
US5584298A (en) * 1993-10-25 1996-12-17 Kabal; John Noninvasive hemodynamic analyzer alterable to a continuous invasive hemodynamic monitor
US5447164A (en) * 1993-11-08 1995-09-05 Hewlett-Packard Company Interactive medical information display system and method for displaying user-definable patient events
US5513645A (en) 1993-11-17 1996-05-07 Ela Medical S.A. Holter functions with a zoom feature
US5458623A (en) 1994-03-04 1995-10-17 Telectronics Pacing Systems, Inc. Automatic atrial pacing threshold determination utilizing an external programmer and a surface electrogram
US5523942A (en) 1994-03-31 1996-06-04 New England Mutual Life Insurance Company Design grid for inputting insurance and investment product information in a computer system
US5507786A (en) 1994-04-14 1996-04-16 Pacesetter, Inc. System and method for measuring and storing parametric data pertaining to operating characteristics of an implantable medical device
US5549654A (en) 1994-04-15 1996-08-27 Medtronic, Inc. Interactive interpretation of event markers in body-implantable medical device
US5464433A (en) 1994-06-14 1995-11-07 Incontrol, Inc. Atrial defibrillator and method providing dual reset of an interval timer
US5535753A (en) 1994-10-04 1996-07-16 Rutgers University Apparatus and methods for the noninvasive measurement of cardiovascular system parameters
US5647369A (en) 1994-10-04 1997-07-15 Rutgers University Apparatus and methods for the noninvasive measurment of cardiovascular system parameters
US5549646A (en) 1994-12-06 1996-08-27 Pacesetter, Inc. Periodic electrical lead intergrity testing system and method for implantable cardiac stimulating devices
US5643255A (en) 1994-12-12 1997-07-01 Hicor, Inc. Steerable catheter with rotatable tip electrode and method of use
US5620472A (en) 1995-01-12 1997-04-15 Pacesetter, Inc. Apparatus and method for dynamically interpreting and displaying a real-time telemetry link
US5749906A (en) 1995-02-21 1998-05-12 Medtronic, Inc. Dual chamber pacing system and method with continual adjustment of the AV escape interval so as to maintain optimized ventricular pacing for treating cardiomyopathy
US5626620A (en) 1995-02-21 1997-05-06 Medtronic, Inc. Dual chamber pacing system and method with continual adjustment of the AV escape interval so as to maintain optimized ventricular pacing for treating cardiomyopathy
US5555888A (en) 1995-02-27 1996-09-17 Brewer; James E. Method for automatic, adaptive, active facilitation to access myocardial electrical instability
US5620474A (en) 1995-04-24 1997-04-15 Vitatron Medical, B.V. System and method for determining indicated pacemaker replacement time based upon battery impedance measurement
US5620471A (en) 1995-06-16 1997-04-15 Pacesetter, Inc. System and method for discriminating between atrial and ventricular arrhythmias and for applying cardiac therapy therefor
US5724985A (en) 1995-08-02 1998-03-10 Pacesetter, Inc. User interface for an implantable medical device using an integrated digitizer display screen
US5759199A (en) 1995-08-02 1998-06-02 Pacesetter, Inc. System and method for ambulatory monitoring and programming of an implantable medical device
US5722999A (en) 1995-08-02 1998-03-03 Pacesetter, Inc. System and method for storing and displaying historical medical data measured by an implantable medical device
US5716382A (en) 1995-08-02 1998-02-10 Pacesetter, Inc. Programmer for an implantable cardiac stimulating device
US5578063A (en) 1995-10-19 1996-11-26 Incontrol, Inc. Implantable atrial defibrillator and system having multiple channel electrogram telemetry and method
US5713937A (en) * 1995-11-07 1998-02-03 Pacesetter, Inc. Pacemaker programmer menu with selectable real or simulated implant data graphics
US5749900A (en) 1995-12-11 1998-05-12 Sulzer Intermedics Inc. Implantable medical device responsive to heart rate variability analysis
US5628321A (en) 1995-12-18 1997-05-13 Diasonics Ultrasound, Inc. Processing velocity information in an ultrasonic system
US5697959A (en) 1996-01-11 1997-12-16 Pacesetter, Inc. Method and system for analyzing and displaying complex pacing event records
US5603331A (en) 1996-02-12 1997-02-18 Cardiac Pacemakers, Inc. Data logging system for implantable cardiac device
US5716383A (en) 1996-02-28 1998-02-10 Medtronic, Inc. Dual chamber pacing system and method with continual adjustment of the AV escape interval so as to maintain optimized ventricular pacing for treating cardiomyopathy
US5607460A (en) * 1996-03-15 1997-03-04 Angeion Corporation Physician interface expert system for programming implantable arrythmia treatment devices
US5683431A (en) 1996-03-27 1997-11-04 Medtronic, Inc. Verification of capture by sensing evoked response across cardioversion electrodes
US5626623A (en) 1996-04-30 1997-05-06 Medtronic, Inc. Method and apparatus for optimizing pacemaker AV delay
US5674249A (en) 1996-05-02 1997-10-07 Incontrol, Inc. Atrial defibrillation system having a portable communication device
US5755736A (en) 1996-05-14 1998-05-26 Medtronic, Inc. Prioritized rule based method and apparatus for diagnosis and treatment of arrhythmias
US5891178A (en) * 1996-05-14 1999-04-06 Pacesetter, Inc. Programmer system and associated methods for rapidly evaluating and programming an implanted cardiac device
US5725559A (en) 1996-05-16 1998-03-10 Intermedics Inc. Programmably upgradable implantable medical device
US5716384A (en) 1996-07-08 1998-02-10 Pacesetter, Inc. Method and system for organizing, viewing and manipulating information in implantable device programmer
US5713366A (en) 1996-09-16 1998-02-03 Sulzer Intermedics Inc. Method and apparatus for dual chamber cardiac analysis
US5755742A (en) 1996-11-05 1998-05-26 Medtronic, Inc. Cardioversion/defibrillation lead impedance measurement system
US5749907A (en) 1997-02-18 1998-05-12 Pacesetter, Inc. System and method for identifying and displaying medical data which violate programmable alarm conditions
US5951484A (en) * 1997-08-01 1999-09-14 Harbinger Medical, Inc. Method of noninvasively determining a patient's susceptibility to arrhythmia
US5974341A (en) * 1997-12-22 1999-10-26 Pacesetter, Inc. Method and apparatus for detecting and displaying diagnostic information in conjunction with intracardiac electrograms and surface electrocardiograms
US6308100B1 (en) * 1997-12-22 2001-10-23 Pacesetter, Inc. Method and apparatus for displaying programming events detected by an implantable medical device
US6289244B1 (en) * 1999-08-20 2001-09-11 Cardiac Pacemakers, Inc. Self audit system
US6418340B1 (en) * 1999-08-20 2002-07-09 Cardiac Pacemakers, Inc. Method and system for identifying and displaying groups of cardiac arrhythmic episodes
US6449504B1 (en) * 1999-08-20 2002-09-10 Cardiac Pacemakers, Inc. Arrhythmia display
US6308102B1 (en) * 1999-09-29 2001-10-23 Stimsoft, Inc. Patient interactive neurostimulation system and method
US6842644B2 (en) * 2001-11-02 2005-01-11 Cardiac Pacemakers, Inc. User navigation and guidance during configuration and storage of parameters for medical device

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"Screenshots taken of Display of Model 2920 Programmer, Using Model 2845 Software Application", Guidant Corporation, 5 pgs, no date.
US 7,010,348, 03/2006, Koshiol et al. (withdrawn)

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10073948B2 (en) 2004-08-06 2018-09-11 Medtronic Minimed, Inc. Medical data management system and process
US8313433B2 (en) * 2004-08-06 2012-11-20 Medtronic Minimed, Inc. Medical data management system and process
US20060031094A1 (en) * 2004-08-06 2006-02-09 Medtronic Minimed, Inc. Medical data management system and process
US20120216297A1 (en) * 2004-08-06 2012-08-23 Medtronic Minimed, Inc. Medical data management system and process
US8715180B2 (en) * 2004-08-06 2014-05-06 Medtronic Minimed, Inc. Medical data management system and process
US20060041288A1 (en) * 2004-08-18 2006-02-23 Medtronic, Inc. Conversational interface for programmable implantable medical device
US20060041222A1 (en) * 2004-08-18 2006-02-23 Medtronic, Inc. Graphical infusion screen interface for programmable implantable medical device
US20100016996A1 (en) * 2006-04-27 2010-01-21 Jeff West Medical device user interface automatically resolving interaction between programmable parameters
US8738560B2 (en) 2006-04-27 2014-05-27 Cardiac Pacemakers, Inc. Systems and methods for automatically resolving interaction between programmable parameters
US7979378B2 (en) 2006-04-27 2011-07-12 Cardiac Pacemakers, Inc. Medical device user interface automatically resolving interaction between programmable parameters
US8321366B2 (en) 2006-04-27 2012-11-27 Cardiac Pacemakers, Inc. Systems and methods for automatically resolving interaction between programmable parameters
US7613672B2 (en) 2006-04-27 2009-11-03 Cardiac Pacemakers, Inc. Medical device user interface automatically resolving interaction between programmable parameters
US20080126968A1 (en) * 2006-04-27 2008-05-29 Jeff West Medical device user interface automatically resolving interaction between programmable parameters
US20090187426A1 (en) * 2006-05-31 2009-07-23 Kerstna Juergen Implantable medical device system and method for adapting functions of the clinician's workstation thereof
US8121689B2 (en) 2007-10-01 2012-02-21 Cardiac Pacemakers, Inc. Proactive interactive limits override for implantable medical device user interface
US9259586B2 (en) * 2008-09-15 2016-02-16 Cardiac Pacemakers, Inc. Systems and methods for highly safe adjustment of device parameters
US20100069991A1 (en) * 2008-09-15 2010-03-18 Cardiac Pacemakers, Inc. Systems and methods for highly safe adjustment of device parameters
US8346369B2 (en) * 2009-05-14 2013-01-01 Cardiac Pacemakers, Inc. Systems and methods for programming implantable medical devices
US20100318155A1 (en) * 2009-05-14 2010-12-16 Cardiac Pacemakers, Inc. Systems and methods for programming implantable medical devices

Also Published As

Publication number Publication date
US20040111131A1 (en) 2004-06-10

Similar Documents

Publication Publication Date Title
US7191006B2 (en) Cardiac rhythm management systems and methods for rule-illustrative parameter entry
US8321366B2 (en) Systems and methods for automatically resolving interaction between programmable parameters
US8725242B2 (en) System and method for displaying a histogram of cardiac events
US8060205B2 (en) Cardiac rhythm management system with user interface for threshold test
US7966069B2 (en) Medical device interface system with automatic rate threshold adjustment
US6594523B1 (en) Implantable stimulation device, programmer, and method for automatically evaluating interaction of the device with a patient's heart
US20100249868A1 (en) Implantable medical device programming apparatus having a graphical user interface
US9533166B2 (en) System and method for correlation of patient health information and device data
US7346393B2 (en) Implantable cardiac rhythm management system having multiple therapy modalities
US20090088815A1 (en) Proactive interactive limits override for implantable medical device user interface
US7457663B2 (en) Cardiac rhythm management system providing control of pacing features with a reduced number of variables
EP2948217B1 (en) Systems to identify cardiac dysynchrony

Legal Events

Date Code Title Description
AS Assignment

Owner name: CARDIAC PACEMAKERS, INC., MINNESOTA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:HU, BO;CAO, WEI;KOSHIOL, ALLAN T.;AND OTHERS;REEL/FRAME:013858/0787;SIGNING DATES FROM 20030207 TO 20030228

STCF Information on status: patent grant

Free format text: PATENTED CASE

FPAY Fee payment

Year of fee payment: 4

FPAY Fee payment

Year of fee payment: 8

MAFP Maintenance fee payment

Free format text: PAYMENT OF MAINTENANCE FEE, 12TH YEAR, LARGE ENTITY (ORIGINAL EVENT CODE: M1553); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY

Year of fee payment: 12