US3807119A - Method of assembling a multiple compartment hypodermic syringe - Google Patents

Method of assembling a multiple compartment hypodermic syringe Download PDF

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US3807119A
US3807119A US00264960A US26496072A US3807119A US 3807119 A US3807119 A US 3807119A US 00264960 A US00264960 A US 00264960A US 26496072 A US26496072 A US 26496072A US 3807119 A US3807119 A US 3807119A
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syringe barrel
syringe
neck portion
assembling
barrel
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W Shields
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00—Closing containers or receptacles after filling
    • B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/28—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
    • B65B7/2821—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers applying plugs or threadless stoppers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/53—Means to assemble or disassemble
    • Y10T29/53313—Means to interrelatedly feed plural work parts from plural sources without manual intervention
    • Y10T29/53322—Means to assemble container
    • Y10T29/53339—Hypodermic syringe
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/53—Means to assemble or disassemble
    • Y10T29/53313—Means to interrelatedly feed plural work parts from plural sources without manual intervention
    • Y10T29/53322—Means to assemble container
    • Y10T29/53343—Means to assemble container including fluid component

Definitions

  • a liquid containing syringe barrel is first fully assembled including a valve in the discharge portion of the barrel, liquid above the valve, a plunger above the liquid, a plunger rod attached to the plunger and a piston cap on the discharge end of the liquid syringe barrel, and subsequently a second syringe barrel is engaged over the discharge end portion of the liquid containing syringe barrel, the piston cap retaining the second syringe barrel on the first or liquid containing syringe barrel. Said assembly of the two syringe barrels is then inverted to permit the filling of powder into the second syringe barrel which is subsequently capped and provided with a sheathed hypodermic syringe needle.
  • the first syringe barrel ' is conveyed to'a fourthassembling station wherea plunger rod is'attached to the plungerfwitha manipulating'portion of the plunger rod extended exteriorly from the first syringe barrel through the open end 2' site ends'of said body 10 arranged with liquid-sealing rings 13 to tightly and slidably engage the bore of the syringe barrel
  • the valves v are delivered from a hopper 14 to the vibratory feeder 8 and the mechanism 9.
  • said syringe barrel is advanced by the vibratory feeder 8 to a filling device 15, at station C, which will delivery a measured quantity of liquid 1', such as a solvent, to the syringe barrel against the valve v having the slit l2 closed by the resiliency of the material of saidvalve.
  • a filling device 15 such as a solvent
  • the syringe barrelS is conveyed by the vibratory feeder 8 to station D where plungers p are delivered from a hopper 16 to the. vibratory, feeder 8 relative to apparatus 17 for inserting a plunger p into the syringe barrel 5 through the open end 6 into proximity with the liquid 1 to seal'said liquid 1 in the syringe barrel 5; As shown in FIG. 4, the plunger p comprises thereof.
  • a vibratory feeder 8 relative to apparatus 17 for inserting a plunger p into the syringe barrel 5 through the open end 6 into proximity with the liquid 1 to seal'said liquid 1 in the syringe barrel 5;
  • the plunger p comprises thereof.
  • a second syringe barrel ' is positioned in vertical spaced alignment below the capped neck portion of the first syringe barrel.
  • the second syringe barrel is moved over the first syringe barrel with the piston cap retaining the second syringe barrel on the firstsyringe barrel.
  • the assembled first and second syringe barrels are inverted and in said inverted position they are conveyed toa ninth as'semblingstation where powder is delivered to the second syringe barrel through a neck portion of said second syringe. barrel and against the capped neck portion of the first syringe barrel.
  • a hypodermic needle carrying cap is successively positioned over the 'pierceable cap and spun to the neck portion of the second syringe barrel.
  • FIGS.- 1A to 1N, inclusive, show the successive steps of assembling a multiple compartment hypodermi y e byrs zgwin h .el mentsiuve y d;
  • FIG. 2 is a diagrammaticplan view of the devices for performing the steps of the-present invention
  • FIG. 3 is a vertical-sectional view of a valve
  • FIG. 4 is a vertical-sectional view of a plunger
  • FIG. 5 is a view of a plunger rod
  • FIG. 6 is a vertical-sectional view of a piston cap.
  • FIG; 2 In carrying out the method ofassembling a multiple compartment hypodermic syringe, there are provided devices or apparatus shown in FIG; 2 as comprising a hopper 4 fora plurality of first syringe barrels 5 having an open filler end 6 and a discharge neckportion 7.
  • the syringe barrels 5 are delivered in a vertical position with the neck portion 7 lowermost to a vibratory feeder 8 conveying said syringe barrels 5 fromstation A to station B where valves v of resilient material, such as rub her, are inserted into the syringe barrels 5 by mechanism 9 to abut the neck portion 7.
  • valves v of resilient material such as rub her
  • the 'valve comprises a tubular body 10 closed by a transverse wall 11 provided with a slit 12 and the oppoa rubber plug 1'8lhaving a recess 19 in the upper end and'liquid-sealing rings 20 to slid-ably engage the bore of the syringe barrel 5.
  • the syringe barrel 5 is conveyed by the vibratory feeder 8 to station E where plunger rods r are delivered from a hopper 21 to a device 22 to insert a plunger rod rinto the recess 19 of the rubber plug 18.
  • plunger rods r comprise a rod 23 having a reduced.
  • the syringe barrel 5 is then conveyed from station E to station F by the vibratory feeder 8 and a rotating table 23 to receive a piston cap 24 of resiliant material, such as rubber, having the closed end or bottom provided with a pair of holes 25 on diametrically/opposite sides of aprotuberance26to plug up the opening in the neck portion 7 and sealing rings 27, as shown in FIG. 6.
  • the caps 24 arede'livered from a hopper 28 by a chute 29to the syringe barrel 5 on the rotating table 23 at station F..
  • the completely assembledsyringe barrel 5 is conveyed by the'rot'ating table 23 'from station F to station G where a second syringe barrel 30is positioned in vertical spaced alignment below theneck portion 7 by a chute 31' delivering saidsyringe barrels 30 from a hopper 32.
  • the stringe barrels 30' have'a bore to snugly fit the sealing rings 27 of the caps 24.
  • the syringe barrel 30 is provided with an open end 33 and a neck portion 34 at the opposite end, and the syringe barrels 30 are delivered and positioned in vertical spaced alignment with the syringe barrel 5with' the open end 33 uppermost.
  • the syringe barrels5 and 30 are conveyed in vertical spaced alignment with each other by the rotating table 23 from station G to station H, where the syringe barrel 30- is moved 'onto the syringe barrel 5 to a predetermined distance toprovide a space between the cap 24 and the neck 'portion'34.
  • the sealing rings 27 will retain thesyringe barrel 30 'on the syringe barrel 5.
  • the connected syringe barrels 5 and 30 are conveyed by the rotatingtable 23 from station H to station I where said connected syringe barrels 5 and 30 are inverted and delivered to a vibratory feeder 35 which conveys the inverted syringe barrels 5 and 30 to a rotating table 36 which conveys said inverted syringe barrels 5 and 30 to a filling device 37 at station J where medicament m in powder form is delivered to the syringe barrel 30 through the neck portion 34.
  • the amount of powder delivered is limited by the space in the syringe barrel 30 between the cap 24 and the neck portion 34.
  • the assembled or connected syringe barrels and 30 are conveyed by the rotating table 36 and rotating tables 38 and 39 to station K where a pierceable closure cap 40 is positioned on the neck portion 34 at the delivery end of a chute 41 receiving said pierceable closure caps 40 from a hopper 42.
  • the assembled syringe barrels 5 and v 30 are conveyed by the rotating table 39 to station L
  • the vibratory feeder 44 conveys the assembled syringe barrels 5 and 30 to station N where a spining device 49 secures the mounting cap 47 to the neck portion 34.
  • the vibratory feeder 44 delivers the fully assembled multiple compartment hypodermic syringe to a suitable depository, not shown.
  • Method of assembling a multiple compartment hypodermic syringe which comprises providing a first syringe barrel open at one end and having a neck portion at the opposite end, inserting a valve into the first syringe barrel through the open end thereof and against the neck portion of the first syringe barrel, delivering a measured quantity of liquid to the first syringe barrel through the open end thereof, inserting a plunger into the first syringe barrel through the open end thereof to retain the liquid in the first syringe barrel, connecting a plunger rod to the plunger through the open end of 4 the first syringe barrel, and applying a piston cap to the neck portion.

Abstract

A liquid containing syringe barrel is first fully assembled including a valve in the discharge portion of the barrel, liquid above the valve, a plunger above the liquid, a plunger rod attached to the plunger and a piston cap on the discharge end of the liquid syringe barrel, and subsequently a second syringe barrel is engaged over the discharge end portion of the liquid containing syringe barrel, the piston cap retaining the second syringe barrel on the first or liquid containing syringe barrel. Said assembly of the two syringe barrels is then inverted to permit the filling of powder into the second syringe barrel which is subsequently capped and provided with a sheathed hypodermic syringe needle.

Description

United States Patent [1 1 Shields [451 Apr. 30, 1974 METHOD OF ASSEMBLING A MULTIPLE COMPARTMENT HYPODERMIC SYRINGE Inventor: Walter A. Shields, Jamaica, NY.
Filed: June 21, 1972 Appl. No.: 264,960
US. Cl 53/22 R, 29/208 B, 128/218 M, 128/220 Int. Cl B65b 3/06, B65b 29/10 Field of Search 53/22 R, 37, 43; 29/208 B; 128/220, 218 M References Cited UNITED STATES PATENTS Primary ExaminerDonald R. Schran ABSIRACT A liquid containing syringe barrel is first fully assembled including a valve in the discharge portion of the barrel, liquid above the valve, a plunger above the liquid, a plunger rod attached to the plunger and a piston cap on the discharge end of the liquid syringe barrel, and subsequently a second syringe barrel is engaged over the discharge end portion of the liquid containing syringe barrel, the piston cap retaining the second syringe barrel on the first or liquid containing syringe barrel. Said assembly of the two syringe barrels is then inverted to permit the filling of powder into the second syringe barrel which is subsequently capped and provided with a sheathed hypodermic syringe needle.
8 Claims, 19 Drawing Figures :RATENTEDAPR 30 ISM 3807-119 sum 3 ur 3 ringe barrel is conveyed to a second assembling station where a measured quantity of liquid is delivered through the open end of the first syringe barrel above I the valve.' From the liquid delivering station, the first syringe barrel is conveyed to a third assembling station where a plunger is inserted through the open end into the first syringe barrel to sealthe liquid in said syringe barrel. From the third assembling station, the first syringe barrel 'is conveyed to'a fourthassembling station wherea plunger rod is'attached to the plungerfwitha manipulating'portion of the plunger rod extended exteriorly from the first syringe barrel through the open end 2' site ends'of said body 10 arranged with liquid-sealing rings 13 to tightly and slidably engage the bore of the syringe barrel The valves v are delivered from a hopper 14 to the vibratory feeder 8 and the mechanism 9.
After the valve v isins erted in the syringe barrel 5, said syringe barrel is advanced by the vibratory feeder 8 to a filling device 15, at station C, which will delivery a measured quantity of liquid 1', such as a solvent, to the syringe barrel against the valve v having the slit l2 closed by the resiliency of the material of saidvalve.
, After the syringe barrel 5 received its measured quantityof liquid 1, the syringe barrelS is conveyed by the vibratory feeder 8 to station D where plungers p are delivered from a hopper 16 to the. vibratory, feeder 8 relative to apparatus 17 for inserting a plunger p into the syringe barrel 5 through the open end 6 into proximity with the liquid 1 to seal'said liquid 1 in the syringe barrel 5; As shown in FIG. 4, the plunger p comprises thereof. At the succeeding fifth assembling station, a
piston cap is engaged over the neck portion of the first syringe barrel and at the succeeding sixth assembling station, a second syringe barrel 'is positioned in vertical spaced alignment below the capped neck portion of the first syringe barrel. At the seventh assembling station, the second syringe barrel is moved over the first syringe barrel with the piston cap retaining the second syringe barrel on the firstsyringe barrel. At the eight assembling station, the assembled first and second syringe barrels are inverted and in said inverted position they are conveyed toa ninth as'semblingstation where powder is delivered to the second syringe barrel through a neck portion of said second syringe. barrel and against the capped neck portion of the first syringe barrel. At
tion. Finally at thetwelfth and thirteenth assembling stations; a hypodermic needle carrying cap is successively positioned over the 'pierceable cap and spun to the neck portion of the second syringe barrel.
In the drawings accompanyingand forming apart of this application: I
FIGS.- 1A to 1N, inclusive, show the successive steps of assembling a multiple compartment hypodermi y e byrs zgwin h .el mentsiuve y d;
FIG. 2 is a diagrammaticplan view of the devices for performing the steps of the-present invention;
FIG. 3 is a vertical-sectional view of a valve;
FIG. 4 is a vertical-sectional view of a plunger;
FIG. 5 is a view of a plunger rod; and
FIG. 6 is a vertical-sectional view of a piston cap.
In carrying out the method ofassembling a multiple compartment hypodermic syringe, there are provided devices or apparatus shown in FIG; 2 as comprising a hopper 4 fora plurality of first syringe barrels 5 having an open filler end 6 and a discharge neckportion 7. The syringe barrels 5 are delivered in a vertical position with the neck portion 7 lowermost to a vibratory feeder 8 conveying said syringe barrels 5 fromstation A to station B where valves v of resilient material, such as rub her, are inserted into the syringe barrels 5 by mechanism 9 to abut the neck portion 7. As shown in FIG. 3, the 'valve comprises a tubular body 10 closed by a transverse wall 11 provided with a slit 12 and the oppoa rubber plug 1'8lhaving a recess 19 in the upper end and'liquid-sealing rings 20 to slid-ably engage the bore of the syringe barrel 5.
From station D, the syringe barrel 5 is conveyed by the vibratory feeder 8 to station E where plunger rods r are delivered from a hopper 21 to a device 22 to insert a plunger rod rinto the recess 19 of the rubber plug 18. As shown in FIG. 5,:said plunger rods r comprise a rod 23 having a reduced. screw-threaded end 24 to be threaded into the recess 19 and a knob 25 at the oppo site erid which ispositioned exteriorly of the open end The syringe barrel 5 is then conveyed from station E to station F by the vibratory feeder 8 and a rotating table 23 to receive a piston cap 24 of resiliant material, such as rubber, having the closed end or bottom provided with a pair of holes 25 on diametrically/opposite sides of aprotuberance26to plug up the opening in the neck portion 7 and sealing rings 27, as shown in FIG. 6. The caps 24 arede'livered from a hopper 28 by a chute 29to the syringe barrel 5 on the rotating table 23 at station F..
The completely assembledsyringe barrel 5 is conveyed by the'rot'ating table 23 'from station F to station G where a second syringe barrel 30is positioned in vertical spaced alignment below theneck portion 7 by a chute 31' delivering saidsyringe barrels 30 from a hopper 32. The stringe barrels 30'have'a bore to snugly fit the sealing rings 27 of the caps 24. The syringe barrel 30 is provided with an open end 33 and a neck portion 34 at the opposite end, and the syringe barrels 30 are delivered and positioned in vertical spaced alignment with the syringe barrel 5with' the open end 33 uppermost.
I The syringe barrels5 and 30 are conveyed in vertical spaced alignment with each other by the rotating table 23 from station G to station H, where the syringe barrel 30- is moved 'onto the syringe barrel 5 to a predetermined distance toprovide a space between the cap 24 and the neck 'portion'34. The sealing rings 27 will retain thesyringe barrel 30 'on the syringe barrel 5.
The connected syringe barrels 5 and 30 are conveyed by the rotatingtable 23 from station H to station I where said connected syringe barrels 5 and 30 are inverted and delivered to a vibratory feeder 35 which conveys the inverted syringe barrels 5 and 30 to a rotating table 36 which conveys said inverted syringe barrels 5 and 30 to a filling device 37 at station J where medicament m in powder form is delivered to the syringe barrel 30 through the neck portion 34. The amount of powder delivered is limited by the space in the syringe barrel 30 between the cap 24 and the neck portion 34.
From station J, the assembled or connected syringe barrels and 30 are conveyed by the rotating table 36 and rotating tables 38 and 39 to station K where a pierceable closure cap 40 is positioned on the neck portion 34 at the delivery end of a chute 41 receiving said pierceable closure caps 40 from a hopper 42.
From station K, the assembled syringe barrels 5 and v 30 are conveyed by the rotating table 39 to station L From station M, the vibratory feeder 44 conveys the assembled syringe barrels 5 and 30 to station N where a spining device 49 secures the mounting cap 47 to the neck portion 34.
From station N, the vibratory feeder 44 delivers the fully assembled multiple compartment hypodermic syringe to a suitable depository, not shown.
Having thus described my invention, I claim:
1. Method of assembling a multiple compartment hypodermic syringe which comprises providing a first syringe barrel open at one end and having a neck portion at the opposite end, inserting a valve into the first syringe barrel through the open end thereof and against the neck portion of the first syringe barrel, delivering a measured quantity of liquid to the first syringe barrel through the open end thereof, inserting a plunger into the first syringe barrel through the open end thereof to retain the liquid in the first syringe barrel, connecting a plunger rod to the plunger through the open end of 4 the first syringe barrel, and applying a piston cap to the neck portion.
2. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 1, providing a second empty syringe barrel open at one end and having a neck portion at the opposite end and having a bore of a diameter to form a tight sliding fit with the piston cap on the-neck portion of the first syringe barrel, positioning said second syringe barrel in vertical spaced alignment below the first syringe barrel with the neck portion of the second syringebarrel lowermost, and raising the second syringe barrel onto the first syringe barrel with the piston cap of the first syringe barrel spaced from the neck portion of the second syringe barrel and retaining the second syringe barrel on the first syringe barrel. I
3. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 2, reversing the vertical positions of the first and second syringe barrels with the second syringe barrel uppermost.
4. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 3, filling the second syringe barrel with powder through the neck portion thereof.
5. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 4, positioning a pierceable closure cap on the neck portion of the second syringe barrel. 1
6. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 5, securing said pierceable closure cap to the neck portion of the second syringe barrel.
7. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 6, positioning an assembled sheathed hypodermic needle and mounting cap on the pierceable closure cap secured to the neck portion of the second syringe barrel.
8. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 7, securing the mounting cap to the neck portion of the second syringe barrel.

Claims (8)

1. Method of assembling a multiple compartment hypodermic syringe which comprises providing a first syringe barrel open at one end and having a neck portion at the opposite end, inserting a valve into the first syringe barrel through the open end thereof and against the neck portion of the first syringe barrel, delivering a measured quantity of liquid to the first syringe barrel through the open end thereof, inserting a plunger into the first syringe barrel through the open end thereof to retain the liquid in the first syringe barrel, connecting a plunger rod to the plunger through the open end of the first syringe barrel, and applying a piston cap to the neck portion.
2. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 1, providing a second empty syringe barrel open at one end and having a neck portion at the opposite end and having a bore of a diameter to form a tight sliding fit with the piston cap on the neck portion of the first syringe barrel, positioning said second syringe barrel in vertical spaced alignment below the first syringe barrel with the neck portion of the second syringe barrel lowermost, and raising the second syringe barrel onto the first syringe barrel with the piston cap of the first syringe barrel spaced from the neck portion of the second syringe barrel and retaining the second syringe barrel on the first syringe barrel.
3. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 2, reversing the vertical positions of the first and second syringe barrels with the second syringe barrel uppermost.
4. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 3, filling the second syringe barrel with powder through the neck portion thereof.
5. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 4, positioning a pierceable closure cap on the neck portion of the second syringe barrel.
6. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 5, securing said pierceable closure cap to the neck portion of the second syringe barrel.
7. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 6, positioning an assembled sheathed hypodermic needle and mounting cap on the pierceAble closure cap secured to the neck portion of the second syringe barrel.
8. Method of assembling a multiple compartment hypodermic syringe as claimed in claim 7, securing the mounting cap to the neck portion of the second syringe barrel.
US00264960A 1972-06-21 1972-06-21 Method of assembling a multiple compartment hypodermic syringe Expired - Lifetime US3807119A (en)

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US5522804A (en) * 1994-02-15 1996-06-04 Lynn; Lawrence A. Aspiration, mixing, and injection syringe
US5586975A (en) * 1994-02-18 1996-12-24 Takeda Chemical Industries. Ltd. Air and liquid tight container with a slidable gasket
US5605542A (en) * 1992-04-30 1997-02-25 Takeda Chemical Industries, Ltd. Prefilled syringe
US5884457A (en) * 1997-02-05 1999-03-23 Smithkline Beecham Corporation Method and apparatus for automatically producing a plurality of sterile liquid filled delivery devices
US6065270A (en) * 1996-12-18 2000-05-23 Schott Glaswerke Method of producing a filled plastic syringe body for medical purposes
US20040088951A1 (en) * 2000-08-10 2004-05-13 Baldwin Brian Eugene Method, system, and apparatus for handling, labeling, filling, and capping syringes
US20040138611A1 (en) * 2000-10-10 2004-07-15 Meridian Medical Technologies, Inc. Wet/dry automatic injector assembly
US20050075602A1 (en) * 1999-10-13 2005-04-07 Societe De Conseils De Recherches Et D'applictaion Scientifiques (S.C.R.A.S.) Device for reconstituting a therapeutic solution, suspension or dispersion
US6915619B2 (en) 2001-08-10 2005-07-12 Baxa Corporation Method for handling syringe bodies
US20060219317A1 (en) * 2000-08-10 2006-10-05 Baldwin Brian E Method, system, and apparatus for handling, labeling, filling, and capping syringes with improved cap
US20100162548A1 (en) * 2006-09-28 2010-07-01 Juergen Leidig Device and method for mounting a needle guard on a syringe body
US20100299904A1 (en) * 2009-05-26 2010-12-02 Angelo Ansaloni Method and apparatus for screwing pistons of syringes
US20110094189A1 (en) * 2008-06-19 2011-04-28 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Method for filling dual-chamber systems in pre-sterilizable carrier systems and pre-sterilizable carrier system
US20110138749A1 (en) * 2009-12-15 2011-06-16 Donald Chow System and method for manufacturing a tubular container with opening and closing means
US20130219710A1 (en) * 2010-11-19 2013-08-29 Michael Jugl Assembly Device for Injection Needles
US20130319576A1 (en) * 2007-04-30 2013-12-05 Medtronic Minimed, Inc. Automated filling systems and methods
US20140223862A1 (en) * 2010-07-16 2014-08-14 Safety Syringes, Inc. Manufacturing Process For Packing Of Injectables
WO2015163751A1 (en) * 2014-04-24 2015-10-29 Meneses Fernández Leopoldo Automated machine for assembling oral medicine dispensers
US9199030B2 (en) 2005-05-06 2015-12-01 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US9522225B2 (en) 2007-04-30 2016-12-20 Medtronic Minimed, Inc. Adhesive patch systems and methods
US20170043896A1 (en) * 2014-04-24 2017-02-16 Leopoldo Meneses Fernandez Automated machine for assembling oral medicament dispensers
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US11027882B2 (en) * 2008-06-19 2021-06-08 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Pre-sterilizable carrier system
US8763350B2 (en) * 2008-06-19 2014-07-01 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Method for filling dual-chamber systems in pre-sterilizable carrier systems
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US20170043896A1 (en) * 2014-04-24 2017-02-16 Leopoldo Meneses Fernandez Automated machine for assembling oral medicament dispensers
WO2015163751A1 (en) * 2014-04-24 2015-10-29 Meneses Fernández Leopoldo Automated machine for assembling oral medicine dispensers
US20210283337A1 (en) * 2017-03-28 2021-09-16 Amgen Inc. Plunger rod and syringe assembly system and method
US11957883B2 (en) * 2018-03-20 2024-04-16 Amgen Inc. Plunger rod and syringe assembly system and method
IT201800009185A1 (en) * 2018-10-05 2020-04-05 Orofino Pharmaceuticals Group Srl Syringe for the reconstitution and injection of a pharmaceutical solution
WO2020070564A1 (en) * 2018-10-05 2020-04-09 Orofino Pharmaceuticals Group Srl Syringe for reconstituting and injecting a pharmaceutical solution

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