|Publication number||US3749085 A|
|Publication date||31 Jul 1973|
|Filing date||17 May 1971|
|Priority date||26 Jun 1970|
|Publication number||US 3749085 A, US 3749085A, US-A-3749085, US3749085 A, US3749085A|
|Inventors||Eskridge M, Willson J|
|Original Assignee||Eskridge M, Willson J|
|Export Citation||BiBTeX, EndNote, RefMan|
|Referenced by (233), Classifications (10)|
|External Links: USPTO, USPTO Assignment, Espacenet|
United States Patent [1 1 Willson et a1.
VASCULAR TISSUE REMOVING DEVICE Inventors: James K. V. Willson; Marshall Eskridge, both of PD. Box 7544, Mobile, Ala. 36607 Filed: May 17, 1971 Appl. No.: 144,029
Related US Application Data Continuation-impart of Ser. No. 50,182, June 26, 1970, Pat. No. 3,683,891.
US. Cl. 128/2 B, 128/305 Int. Cl A6lb 10/00 Field of Search 128/2 B, 2 M, 2 R, 128/D1G. 9, 304, 305, 310, 328; 15/104.3 G,
References Cited UNITED STATES PATENTS 566,110 8/1896 Wrigley 15/104.3 SN
[451 July 31, 1973 2,631,114 I 3/1953 O'Brien 15/1043 SN 2,694,822 11/1954 Murphy 15/1043 G 2,739,585 3/1956 Ayre 128/2 B 2,955,592 10/1960 MacLean 128/2 B 3,342,175 9/1967 Bulloch 128/2'B 3,452,740 7/1969 Muller 128/2 M 3,628,522 12/1971 Kato 128/2 B Primary Examiner-Kyle L. Howell Attorney-Christen & Sabol  ABSTRACT A device for removing specimens of vascular tissue by scraping various portions of the area to be sampled is formed by a multi-strand coil of wires, the ends of the wires being cut to define radially projecting, axially offset cutters, the device being guided by remote control 12 Claims, 9 Drawing Figures PATENIEU I915 3.749.085
'sum 1 OF 2 nv vE/vfoks JAMES K. v WILLSON MARSHALL [SKIP/06E ATTORNEYS PATENIEUJUW 19H 3.749.085
, sum 2 or a INVENTORS JAMES K. L WILLSON MARSHALL E SKR/OGE BYMMM ATTORNEYS VASCULAR TISSUE REMOVING DEVICE This application is a continuation in part of our earlier copending application, Ser. No. 50,182, filed June 26, 1970, entitled TISSUE AUGER, now US. Pat. No. 3683891.
The-present invention relates to means for performing biopsies and more particularly to a vascular tissue removing device having a scraping tool provided with a plurality of sharp cutters.
Such biopsy devices are used to remove vascular tissues, for example from the lung branches, with the purpose of examination to make a medical diagnosis. At present, devices are known which utilize a so-called auger" action similar to that employed by the common wood auger which resembles a flat strip twisted about its longitudinal axis and terminating in a radially disposed knife. However, all these devices are directed to the extraction of a tissue core from a defined location, whereas in some instances it is more interesting to obtain a tissue sample from the surface of a relatively wide area. This can but be achieved by scraping the de sired surface.
Such devices for removing specimens of tissue by scraping or rubbing are also known, for example in form of brushes, but the action of such tools is uncertain both as to effectiveness and to the amount of the specimen removed. Furthermore, the known devices are suitable for a longitudinal scraping action, but not for a rotating scraping action, since their considerable length and flexibility makes them inappropriate for transmitting a rotational torque.
It is, therefore, an object of the present invention to provide a vascular tissue removing device having a tissue scraping tool to be rotated and which can effectively scrape extended areas of the end or side walls of the branch of the cavitY to be examined and remove determined amounts therefrom.
It is another object of the invention to provide a device which can be guided and operated from the outside of a living body to be examined.
It is a further object of the invention to provide a de vice which can efficiently transmit a rotational torque from the outside of a living body to the operating tool in the inside of said living body.
To realize these objects the present invention comprises a vascular tissue removing device having a tissue scraping tool to be rotated around an axis and including a plurality of cutters substantially radially projecting with respect to this axis of rotation. In addition, the cutters may be partially axially offset with respect to the axis of rotation of the tool, so that tissue portions of different parts of a relatively wide area may be simultaneously scraped. There are several ways in which the tool may be guided to the location where it is to be used. It may be done by first inserting a hollow needle into the tissue to the location to be examined and the tool then inserted to that spot through the hollow. On the other hand, if the tissue to be examined lies within a branched cavity, such as the lungs, the tool may be attached to the end of a flexible deflecting probe and guided to the location by the probe.
Further, in one form of the invention, the tissue scraping tool forms the extremity of a flexible helical coilof wire which, in turn, may be guided to the area in question by means of a deflecting probe.
In addition, the invention also consists of an improved form of deflecting probe means having a multistrand helical coil to provide greater rotational torque for the tool than is possible by means of known deflecting probes and which, in addition, provides more accurate control of the directing of the probe means.
Other objects and advantages will be apparent after the reading the following description in connection with the drawings, in which:
FIG. 1 is a view in elevation, on a greatly enlarged scale, of one form of tissue scraping tool made in accordance with this invention;
FIG. 2 is an end elevation of the device of FIG. 1, showing the position of the cutting means;
FIG. 3 is an end elevation of a modified form of a scraping tool made in accordance with this invention;
FIG. 4 is a view in elevation of the tissue scraping device of FIG. 1, on a reduced scale, forming the extremity of an improved type of deflecting probe in accordance with the invention;
FIG. 5 is an enlarged fragmentary section of the bending portion of the improved deflecting probe;
FIG. 6 is a view in elevation of the tissue scraping device of FIG. 1 using a conventional probe solely as a guiding means;
FIG. 7 is a side elevation of a plastic catheter employed in inserting the probe into a branched cavity;
FIG. 8 is a side view of an assembly of two catheters, the scraping device of the invention and a conventional deflecting probe, which can be employed in exploring a branched cavity; and
FIG. 9 is a diagrammatic representation of the method employed in using the device of FIG. 8.
Referring now to the Figures, FIGS. 1 and 2 show a preferred embodiment of a tissue scraping tool according to the invention, indicated generally by numeral 11. This device comprises a single layer multistrand helically wound coil of wires, having preferably four wires 12, 13,14 and 15, and defining a leading end 16, an intermediate portion 17 behind said leading end and a trailing portion 18 behind said intermediate portion, said trailing portion 18 being only partially illustrated in FIG. 1. The four wires forming the scraping tool may be fabricated of fine stainless steel spring wire which is strong and substantially inert with respect to bodyand tissue fluids.
As an example, although not to be considered as a limitating one, each of the four spirally coiled wires, of round stainless steel may have an approximate diameter of 0.020 inch, while the outside diameter of the coil may be approximatey 0.090 inch. Where wire 15 reaches the intermediate portion 17 it is terminated in a sharpened and pointed tissue cutter which is slightly bent to define a cutter l9 projecting partially radially outwardly from said intermediate portion. In the direction towards the leading end 16 and in front of cutter 19 the coil only comprises wires l2, l3 and 14. Further on toward the leading end, preferably after two and a half turns, wire 14 is cut, in a similar way as wire 15, into a sharpened and pointed tissue cutter and is slightly bent to define a cutter 20 projecting partially radially outwardly from said intermediate portion. After another two and a half turns the remaining wires 12 and 13 are cut in the plane normal to the axis of the device into respective sharpened and pointed tissue cutters 21 and 22.
Thus, as the tool is rotated, both the first tissue cutters 21 and 22 arranged at the leading end 16, and the second tissue cutters l9 and 20 arranged at the intermediate portion 17 of the coil will simultaneously scrape different parts of the area to be sampled. The gaps 23 and 24, originated by the removal of the respective wires and 14 which have been cut off, and located between subsequent turns of the unremoved wires 14 and 12, and 13 and 12, respectively, will receive the scraped material and lead it to the interior of the coil, so that the risk of loosing the specimen while extracting the scraping device from the living body is completely eliminated. Moreover, the obtained specimen will comprise surface portions of an area whose size is at least equivalent to the distance between cutters 19 and 21. I
In addition, the cutters 21 and 22 located at the leading end of the tool permit not only a circumferential scraping of the lateral surfaces of a tissue portion but also the extraction of a tissue core, for example from the end surface of a lung branch positioned in a sub stantially normal plane to the axis of the scraping device.
While the described arrangement of the cutters is particularly suitable due to the symmetrical and regular location of the cutters, shown in FIG. 2, it is apparent that any other distribution of the cutters at the leading end and along the intermediate portion can be chosen without departing from the scope of the invention. Also, instead of four wires any desired number of wires can be utilized to define the cutters, the only requirement being that they project partially radially outwardly from the axis of the scraping device and that they are partially axially offset with respect to said axis. Thus, instead of forming the cutters at the ends of the wires of a coil, the scraping tool could be a cylindrical body made of steel sheet and provided with pointed portions projecting outwardly of said body.
According to another embodiment of the invention, shown in FIG. 3, the four wires of the multi-strand coiled wire have each the same length, and their terminal ends are cut off in a plane normal to the axis of the coil and may be bent outwardly to form a sort of rosette composed of four equi-angularly spaced sharpened cutters, 19', 20', 21' and 22', which may be used to scrape a tissue surface and to pierce and grip a small specimen of tissue for removal by withdrawal of the device in an axial direction. Preferably, in this embodiment the leading ends of the cutters are serrated.
Since the instruments just described represent a basic tool, the scraping device embracing the invention concept just described is capable of several modifications. For example, the tool as described may be employed to reach internal organs by the use ofa hollow needle provided with an angled tip and having an internal diameter large enough to aecomodate the present tissue scraping device therein for movement to the site of biopsy conducted by an elongated shank extending outwardly of the other end of the needle and for removal of the core specimens through the needle.
Another system for guiding the tool to the site for use and for manipulating it is to attach the tool to the extremity of a deflecting type probe such as is known as a Muller" wire. This type of device is particularly useful in exploring the various branches of the oral and nasal cavities. A typical Muller deflecting tip comprises a tightly wound wire probe having a central con- 4. trol wire passing therethrough. Over an area of flexure near the forward end of the tip, the coiled wires are reduced in diameter over adjacent half turns so that tension produced at the end of the tip by the control wire, causes deflection.
Deflecting type probes of the type discussed above are disclosed in U. S. Pat. No. 3,452,740 and No. 3,452,742, granted to W. F. Muller on July I, I969, while another form of device of this type is shown in U. S. Pat. No. 3,521,620 granted to W. A. Cook on July 28, 1970, and no claim is made to this form of deflecting probe per se.
According to the invention, the elongated trailing portion 18 which is adapted to guide the scraping tool to the site for use and to manipulate it comprises a single layer multi-strand helical coil, shown in FIGS. 1 and 4, which provides a greater rotational torque for a tool attached to the extremity thereof than is possible by means of the single wire of the known deflecting probes. According to a preferred embodiment, this trailing portion 18 located behind the intermediate portion 17 comprises the same four wires 12, 13, 14 and 15 which form the previously described tools, these wires having the same diameter and pitch of the helix and being wound into a four-strand helical coil, the turns of which lie closely adjacent each other, except for a portion of its length next to the end defining the guide section or flexure area 25, shown in FIG. 5, of the probe. The bending effect is accomplished in a known way, already described in connection with the Muller" wire, and is not part of the invention. The central core wire 26 is also conventional, lies inside the coil 18, and is soldered in 27 to the front end of the trailing portion 18. Thus, when the direction of the front portion of the probe is changed, it urges the attached device to point in the desired direction. The tool means, which extend beyond the end of said probe, can then be rotated to collect the desired specimen of tissue.
The capacity of transmitting a greater rotational torque results from the facts that the number of turns of each single helical wire decreases proportionally to the increase of the number of wires forming the multistrand coil, and that the elasticity of the coil depends, among other factors, from the number of turns of the wires.
Thus, this improved deflecting probe means is particularly useful in the embodiment of FIG. 4, since it offers an increased capability of transmitting rotational torque along the portion 18, which results in a better control of rotational torque from the control means to the tip portion.
It should also be obvious that this improved deflecting probe means comprising a multi-strand helical coil, according to the invention, can be used in connection with brushes, augers or any other kind of tools which require a rotational movement of the deflecting probe means.
The extremity of the deflecting probe is inserted, together with the tissue cutters, into the vascular system from the exterior ofa living body, for guidance and operation of the tissue cutters from the exterior of said body by manual manipulation of the elongated trailing portion. The other end of the deflecting probe to be disposed exteriorly of a living body is provided with manual control means 28 having one element 29 fixedly connected with the single layer wire coil 18 for exerting positive rotation to a scraping tool 11 at the leading end of the coil, and a second element 30 is fixedly connected with said straight flexible wire 26 for exerting axial compression on the flexurc area.
In another form of the scraping device a conventional deflecting tip, such as a Muller wire, or the deflecting probe of the present invention, is employed solely as a guide means. The scraping device is constructed generally as previously described with the exception that the trailing portion consists of a uniform multistrand wire coil, without having a flexure area nor a central core wire, which passes over into the scraping tool 11 having an intermediate portion 17 provided with the cutters 19 and 20 and a leading end 16 pro vided with the cutters 21 and 22.
The inner diameter of the tool according to this modification is such that the deflecting probe means may be pushed completely through the tool to serve as a guide to reach the desired location, and the length of the coiled wire forming the trailing portion of the tool is such that it will extend along the entire length of the deflecting probe means to permit rotation of the tool, either when the deflecting tip has been partially, or completely, removed from the interior of the trailing portion. With this form of the invention, instead of attaching the cutter 11 to a deflecting probe and using the deflecting probe to both guide and rotate the cutter, the deflecting probe 31 may be used solely to guide the cutter II to the remote portion of the cavity, after which the probe can be removed and the cutter manipulated by manually rotating the other extremity of the trailing portion 18, as shown in FIG. 6.
In this case the inside diameter of the helix forming the trailing portion 18 and cutter 11 should be such that the entire length of the device may be easily slid over the exterior of a deflecting probe 31, and the length of the coil should be sufficient to permit the remote end of the coiled wire to extend outwardly of the cavity into which the tool is inserted and to be secured to an annular portion 32. By manually gripping the annular portion 32 the cutter and trailing portion may be rotationally and axially manipulated, independently of the deflecting probe means indicated generally by numeral 31. In practice, the length of the coil does not usually exceed 2 to 3 feet.
FIGS. 7 to 9 show a particularly useful application of the scraping device of FIG. 6 and a method for removing tissue from the interior of a living body usingthis particular combination.
It is known that tubular devices to be inserted into living bodies, commonly known as catheters, may be manufactured of a semi-rigid material such as plastic, and that during the manufacture of these plastic cathe ters any desired form may be given to them, so that this form remains inherent to the catheter even ifdue to its semi-rigid nature the catheter is forced to momentarily adopt a different form.
This quality is illustrated in FIG. 7 which shows a J- shaped catheter 33, that is, a catheter which has the tendency to bend into a .l-form defining a substantially right angle at its leading portion. However, due to its semi-rigid nature this catheter can be forced into a straight line indicated by dotted lines.
FIG. 8 shows the combination of an .l-shaped catheter 33 with a straight catheter 34, the outer diameter of catheter 33 being slightly smaller than the inner diameter of catheter 34, so that both catheters are in axially and rotatably slidable' relationship to each other.
Within catheter 33 a scraping device according to the invention, and particularly as shown in FIG. 6, is located in axially and rotatably slidable relationship thereto. That is, the inner diameter of catheter 33 is slightly larger than the outer diameter of the trailing portion 18 and the scraping tool I]. As already mentioned, a conventional deflecting probe 3] is slidably located within the scraping device.
A method of using the above described combination to remove tissue specimens from the interior of a living body consists in first inserting a normally J-shaped semi-rigid catheter 33 into the interior of a larger straight catheter 34, so that catheter 33 momentarily adopts the straight form of catheter 34. Both catheters are inserted into the oral cavity 35 of a body until the leading end of catheter 34 reaches a primary branch in said cavity, indicated for example with 36 in FIG. 9. Catheter 33 is now axially oriented and advanced with respect to catheter 34, so that its leading end protrudes from catheter 34, bends to recover its inherent form and enters said branch 36. Subsequently, a longitudinally and angularly basically inflexible but radially flexible biopsy device, such as the tissue scraping device according to the invention is inserted into said catheter 33 and advanced into the primary branch 36 beyond the end of catheter 33. The bent end portion of catheter 33 thus provides an accurate and constant guide for the advancing leading portion of tool 11 into a secondary branch 37, to the desired area 38 to be sampled, by the guiding action of the deflecting probe 31. When the tool 11 has reached the area 38, as indicated by dotted lines, the probe 31 is partially or totally withdrawn, so that the tool can be rotated from the outside of the body, as described above, to capture a tissue specimen. Due to the ability of the device according to the invention to transmit rotational torque, and to the design of the tool, a desired amount of tissue can be easily removed from the area 38 and be effectively withdrawn when the tool is retrieved from the cavity through the catheters.
It will be understood that this method described above can also be used in connection with a device as shown in FIG. 4, where the scraping device and the deflecting probe are unitary.
It will further be understood that while the examples described illustrate various modifications of the invention, they are not to be considered as limiting. The dimensions and types of materials may be varied within reasonable limits.
The claims are:
l. A vascular tissue removing device comprising a tissue scraping tool to be rotated around an axis and having a plurality of cutters substantially radially projecting with respect to said axis of rotation, means for transmitting a rotational torque and a longitudinal movement to said tool and connected to said plurality of cutters, said means comprising a single layer multistrand closely spaced helically wound coil of wires, and means for guiding the direction of said longitudinal movement.
2. A device as defined in claim 1, wherein said plurality of cutters are partially axially offset along the longitudinal axis of the tool.
3. A device as defined in claim 2, wherein said means for guiding said longitudinal movement of the tool includes a tubular element surrounding said tool, and said means for transmitting a rotational torque and a longitudinal movement to said tool includes an elongated shank extending outwardly of the other end of the tubular element.
4. A device as defined in claim I, wherein said plurality of cutters comprises the terminal ends of the wires of the helically wound coil, said coil being cut off in a plane normal to the axis of the helix and said terminal ends projecting partially radially outwardly from the periphery of said coil to define a rosette-shaped tool.
5. A device as defined in claim 1, wherein said single layer multi-strand helically wound coil of wires has a leading end, an intermediate portion behind the leading end and an elongated trailing portion behind the intermediate portion, at least one of said wires terminating at the leading end of the coil in a first sharpened tissue cutter, and at least one of the other wires of the coil terminating in a second sharpened tissue cutter projecting partially radially outwardly from said intermediate portion behind said first cutter.
6. A device as defined in claim 5, wherein each ofthe wires forming said single layer coil terminates in a sharpened tissue cutter.
7. A device as defined in claim 6, wherein at least two of said wires forming said coil terminate at the leading end of the coil in sharpened tissue cutters.
8. A device as defined in claim 7, wherein at least two of the wires forming said tissue cutters terminate at locations spaced from each other axially of the coil.
9. A device as defined in claim 8, wherein said single layer multi-strand helically wound coil comprises at least four helical wires with substantially the same diameter and the same pitch of the helix, at least two of said wires terminating in sharpened tissue cutters axially spaced from each other and from the leading end of the coil.
10. A device as defined in claim 5, wherein said elongated trailing portion is radially flexible for insertion of the tissue cutters into the vascular system from the exterior of a living body and for operation of said tissue cutters from the exterior of said body by manual manipulation of said elongated trailing portion.
11. A device as defined in claim 10, wherein the turns of said helical wires in said trailing portion are disposed in axially abutting relation, certain of said turns comprising a direction--changing flexure area, the axial thickness of adjacent portions of each of the turns of wire at said flexure area being reduced over approximately one-half of the adjacent circumferences thereof, a straight flexible wire being connected at one end with the extremity of the trailing portion adjacent said intermediate portion for exerting axial compression on the flexure area for altering the longitudinal curvature of said flexure area of the trailing portion.
12. A device as defined in claim 11, wherein the extremity of said trailing portion to be disposed exteriorly ofa living body is provided with manual control means, said control means being fixedly connected with said single layer wire coil for exerting positive rotation to said cutters at the leading end of the coil, and with said straight flexible wire for exerting axial compression on the trailing portion.
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3941119 *||19 Jul 1974||2 Mar 1976||Mario Corrales||Means for introducing and guiding objects into body cavities and blood vessels|
|US4020829 *||23 Oct 1975||3 May 1977||Willson James K V||Spring guide wire with torque control for catheterization of blood vessels and method of using same|
|US4030503 *||5 Nov 1975||21 Jun 1977||Clark Iii William T||Embolectomy catheter|
|US4057149 *||17 Feb 1976||8 Nov 1977||Rogers And Clarke Manufacturing Co.||Mechanism for transferring parts|
|US4108162 *||21 Dec 1976||22 Aug 1978||Kiyoshi Chikashige||Twisted wire brush with threaded assembly for collecting cells|
|US4271845 *||2 Jul 1979||9 Jun 1981||Kabushiki Kaisha Medos Kenkyusho||Device for bending a medical instrument inserted into the body cavity|
|US4445509 *||4 Feb 1982||1 May 1984||Auth David C||Method and apparatus for removal of enclosed abnormal deposits|
|US4653496 *||1 Feb 1985||31 Mar 1987||Bundy Mark A||Transluminal lysing system|
|US4655217 *||11 Oct 1985||7 Apr 1987||Reed Matt H||Method and apparatus for disabling vein valves in-situ|
|US4696667 *||20 Mar 1986||29 Sep 1987||Helmut Masch||Intravascular catheter and method|
|US4790812 *||15 Nov 1985||13 Dec 1988||Hawkins Jr Irvin F||Apparatus and method for removing a target object from a body passsageway|
|US4898575 *||10 Jun 1988||6 Feb 1990||Medinnovations, Inc.||Guide wire following tunneling catheter system and method for transluminal arterial atherectomy|
|US4909781 *||19 Jul 1989||20 Mar 1990||Husted Royce Hill||Catheter with flexible cutter|
|US4919146 *||25 Oct 1988||24 Apr 1990||Medrad, Inc.||Biopsy device|
|US4922924 *||27 Apr 1989||8 May 1990||C. R. Bard, Inc.||Catheter guidewire with varying radiopacity|
|US4932419 *||21 Mar 1988||12 Jun 1990||Boston Scientific Corporation||Multi-filar, cross-wound coil for medical devices|
|US4936845 *||21 Jun 1989||26 Jun 1990||Cordis Corporation||Catheter system having distal tip for opening obstructions|
|US4951677 *||21 Mar 1988||28 Aug 1990||Prutech Research And Development Partnership Ii||Acoustic imaging catheter and the like|
|US4979951 *||18 Jan 1989||25 Dec 1990||Simpson John B||Atherectomy device and method|
|US5065769 *||18 Jan 1991||19 Nov 1991||Boston Scientific Corporation||Small diameter guidewires of multi-filar, cross-wound coils|
|US5078723 *||19 Dec 1990||7 Jan 1992||Medtronic, Inc.||Atherectomy device|
|US5116350 *||14 Jun 1990||26 May 1992||Cordis Corporation||Catheter system having distal tip for opening obstructions|
|US5131406 *||19 Sep 1990||21 Jul 1992||Martin Kaltenbach||Guide for introduction of catheters into blood vessels and the like|
|US5197482 *||2 Apr 1991||30 Mar 1993||Research Corporation Technologies, Inc.||Helical-tipped lesion localization needle device and method of using the same|
|US5217474 *||15 Jul 1991||8 Jun 1993||Zacca Nadim M||Expandable tip atherectomy method and apparatus|
|US5234451 *||15 Nov 1991||10 Aug 1993||Peter Osypka||Apparatus for eliminating occlusions and stenoses in body cavities|
|US5308354 *||10 Dec 1991||3 May 1994||Zacca Nadim M||Atherectomy and angioplasty method and apparatus|
|US5336234 *||7 May 1993||9 Aug 1994||Interventional Technologies, Inc.||Method and apparatus for dilatation of a stenotic vessel|
|US5423799 *||28 Jan 1993||13 Jun 1995||Medtronic, Inc.||Surgical instrument|
|US5524630 *||17 May 1995||11 Jun 1996||Crowley; Robert J.||Acoustic imaging catheter and the like|
|US5527326 *||7 Nov 1994||18 Jun 1996||Thomas J. Fogarty||Vessel deposit shearing apparatus|
|US5601599 *||23 Sep 1994||11 Feb 1997||Symbiosis Corporation||Flexible surgical instruments incorporating a hollow lumen coil having areas of different preload tension|
|US5630806 *||24 Aug 1995||20 May 1997||Hudson International Conductors||Spiral wrapped medical tubing|
|US5715825 *||10 Jun 1996||10 Feb 1998||Boston Scientific Corporation||Acoustic imaging catheter and the like|
|US5766192 *||16 Oct 1996||16 Jun 1998||Zacca; Nadim M.||Atherectomy, angioplasty and stent method and apparatus|
|US6001112 *||10 Apr 1998||14 Dec 1999||Endicor Medical, Inc.||Rotational atherectomy device|
|US6165127 *||26 Sep 1997||26 Dec 2000||Boston Scientific Corporation||Acoustic imaging catheter and the like|
|US6206898||1 Mar 1999||27 Mar 2001||Endicor Medical, Inc.||Rotational atherectomy device|
|US6210395||20 Oct 1997||3 Apr 2001||Lake Region Mfg., Inc.||Hollow lumen cable apparatus|
|US6238405||30 Apr 1999||29 May 2001||Edwards Lifesciences Corp.||Percutaneous material removal device and method|
|US6364840||27 Sep 2000||2 Apr 2002||Boston Scientific Corporation||Acoustic imaging catheter and the like|
|US6440147||4 May 2000||27 Aug 2002||Rubicor Medical, Inc.||Excisional biopsy devices and methods|
|US6443966||16 Oct 1997||3 Sep 2002||Intravascular Medical, Inc.||Surgical instrument|
|US6451036||12 Jun 2000||17 Sep 2002||Endicor Medical, Inc.||Rotational atherectomy system with stationary cutting elements|
|US6454779||4 Oct 1999||24 Sep 2002||Endicor Medical, Inc.||Rotational atherectomy device|
|US6482217||7 Sep 2000||19 Nov 2002||Endicor Medical, Inc.||Neuro thrombectomy catheter|
|US6572553||4 Jan 2002||3 Jun 2003||Scimed Life Systems, Inc.||Medical imaging device|
|US6585655||31 May 2002||1 Jul 2003||Scimed Life Systems, Inc.||Medical imaging device|
|US6602264||11 Feb 2000||5 Aug 2003||Rex Medical, L.P.||Rotational thrombectomy apparatus and method with standing wave|
|US6623495||18 Jan 2001||23 Sep 2003||Edwards Lifesciences Corporation||Percutaneous material removal device tip|
|US6666874||17 Sep 1999||23 Dec 2003||Endicor Medical, Inc.||Rotational atherectomy system with serrated cutting tip|
|US6685696||9 Feb 2001||3 Feb 2004||Lake Region Manufacturing, Inc.||Hollow lumen cable apparatus|
|US6764495||14 Mar 2002||20 Jul 2004||Rubicor Medical, Inc.||Excisional biopsy devices and methods|
|US6790215||2 Mar 2001||14 Sep 2004||Edwards Lifesciences Corporation||Method of use for percutaneous material removal device and tip|
|US6849080||31 Jan 2002||1 Feb 2005||Rubicon Medical, Inc.||Excisional biopsy device and methods|
|US6863676||31 Jan 2002||8 Mar 2005||Rubicor Medical, Inc.||Excisional biopsy devices and methods|
|US6926725||17 Mar 2003||9 Aug 2005||Rex Medical, L.P.||Thrombectomy device with multi-layered rotational wire|
|US6936014||16 Oct 2002||30 Aug 2005||Rubicor Medical, Inc.||Devices and methods for performing procedures on a breast|
|US7029451||6 Nov 2002||18 Apr 2006||Rubicor Medical, Inc.||Excisional devices having selective cutting and atraumatic configurations and methods of using same|
|US7037271||27 May 2003||2 May 2006||Boston Scientific Corporation||Medical imaging device|
|US7037316||1 Apr 2002||2 May 2006||Mcguckin Jr James F||Rotational thrombectomy device|
|US7044956||16 Oct 2002||16 May 2006||Rubicor Medical, Inc.||Methods and devices for cutting and collecting soft tissue|
|US7104966||16 Jul 2003||12 Sep 2006||Samuel Shiber||Guidewire system with exposed midsection|
|US7122011||18 Jun 2003||17 Oct 2006||Rubicor Medical, Inc.||Methods and devices for cutting and collecting soft tissue|
|US7153314||16 Aug 2002||26 Dec 2006||Ndo Surgical||Tissue reconfiguration|
|US7172610||17 Oct 2003||6 Feb 2007||Ev3 Endovascular, Inc.||Rotational atherectomy system with stationary cutting elements|
|US7198626||23 Jan 2003||3 Apr 2007||Rubicor Medical, Inc.||Methods and devices for radiofrequency electrosurgery|
|US7235088||19 Jul 2002||26 Jun 2007||Ev3 Endovascular, Inc.||Neuro thrombectomy catheter|
|US7291158||12 Nov 2004||6 Nov 2007||Boston Scientific Scimed, Inc.||Cutting balloon catheter having a segmented blade|
|US7303531||8 Mar 2004||4 Dec 2007||Rubicor Medical, Inc.||Excisional biopsy devices and methods|
|US7329253||9 Dec 2003||12 Feb 2008||Rubicor Medical, Inc.||Suction sleeve and interventional devices having such a suction sleeve|
|US7438693||6 Jun 2005||21 Oct 2008||Rubicor Medical, Inc.||Devices and methods for performing procedures on a breast|
|US7479147||14 Dec 2000||20 Jan 2009||Ev3 Endovascular, Inc.||Rotational atherectomy device|
|US7507246||21 Sep 2005||24 Mar 2009||Rex Medical, L.P.||Rotational thrombectomy device|
|US7517348||20 Aug 2004||14 Apr 2009||Rubicor Medical, Inc.||Devices and methods for performing procedures on a breast|
|US7566319||21 Apr 2004||28 Jul 2009||Boston Scientific Scimed, Inc.||Traction balloon|
|US7615013||25 May 2006||10 Nov 2009||Rubicor Medical, Inc.||Methods and devices for cutting and collecting soft tissue|
|US7632288||12 May 2003||15 Dec 2009||Boston Scientific Scimed, Inc.||Cutting balloon catheter with improved pushability|
|US7645261||4 Nov 2005||12 Jan 2010||Rex Medical, L.P||Double balloon thrombectomy catheter|
|US7713277||21 Apr 2004||11 May 2010||Ethicon Endo-Surgery, Inc.||Tissue reconfiguration|
|US7722633||8 Apr 2004||25 May 2010||Ethicon Endo-Surgery, Inc.||Tissue reconfiguration|
|US7736373||8 Apr 2004||15 Jun 2010||Ndo Surical, Inc.||Methods and devices for tissue reconfiguration|
|US7754047||8 Apr 2004||13 Jul 2010||Boston Scientific Scimed, Inc.||Cutting balloon catheter and method for blade mounting|
|US7758604||29 May 2003||20 Jul 2010||Boston Scientific Scimed, Inc.||Cutting balloon catheter with improved balloon configuration|
|US7771445||20 Jun 2002||10 Aug 2010||Ev3 Endovascular, Inc.||Rotational atherectomy system with stationary cutting elements|
|US7776057||19 Nov 2004||17 Aug 2010||Ethicon Endo-Surgery, Inc.||Methods and devices for tissue reconfiguration|
|US7780626||8 Aug 2003||24 Aug 2010||Boston Scientific Scimed, Inc.||Catheter shaft for regulation of inflation and deflation|
|US7819887 *||20 Dec 2004||26 Oct 2010||Rex Medical, L.P.||Rotational thrombectomy wire|
|US7842055||21 Jul 2006||30 Nov 2010||Ev3 Endovascular, Inc.||Neuro thrombectomy catheter|
|US7846180||2 Oct 2003||7 Dec 2010||Ethicon Endo-Surgery, Inc.||Tissue fixation devices and methods of fixing tissue|
|US7857823||8 Apr 2004||28 Dec 2010||Ethicon Endo-Surgery, Inc.||Tissue reconfiguration|
|US7867176 *||27 Dec 2005||11 Jan 2011||Cordis Corporation||Variable stiffness guidewire|
|US7887557||14 Aug 2003||15 Feb 2011||Boston Scientific Scimed, Inc.||Catheter having a cutting balloon including multiple cavities or multiple channels|
|US7896893||8 Apr 2004||1 Mar 2011||Ethicon Endo-Surgery, Inc.||Methods and devices for tissue reconfiguration|
|US7909801||4 Dec 2009||22 Mar 2011||Rex Medical, L.P.||Double balloon thrombectomy catheter|
|US7955253||19 Dec 2005||7 Jun 2011||Usgi Medical, Inc.||Apparatus and methods for achieving endoluminal access|
|US7993358||24 Mar 2009||9 Aug 2011||Boston Scientific Scimed, Inc.||Cutting balloon catheter having increased flexibility regions|
|US8038691||12 Nov 2004||18 Oct 2011||Boston Scientific Scimed, Inc.||Cutting balloon catheter having flexible atherotomes|
|US8057494||18 Mar 2009||15 Nov 2011||Ethicon Endo-Surgery, Inc.||Methods and devices for tissue reconfiguration|
|US8062317||11 Aug 2010||22 Nov 2011||Rex Medical, L.P.||Rotational thrombectomy wire|
|US8066727||30 Apr 2007||29 Nov 2011||Rubicor Medical Llc||Methods and devices for cutting and collecting soft tissue|
|US8123769||11 Aug 2006||28 Feb 2012||Cook Medical Technologies Llc||Thrombus removal device|
|US8172864||15 Dec 2009||8 May 2012||Boston Scientific Scimed, Inc.||Balloon catheter with improved pushability|
|US8192452||14 May 2010||5 Jun 2012||Tyco Healthcare Group Lp||Easily cleaned atherectomy catheters and methods of use|
|US8216260||25 Aug 2008||10 Jul 2012||Usgi Medical, Inc.||Apparatus and methods for forming and securing gastrointestinal tissue folds|
|US8226674||9 Apr 2010||24 Jul 2012||Tyco Healthcare Group Lp||Debulking catheters and methods|
|US8246640||18 May 2006||21 Aug 2012||Tyco Healthcare Group Lp||Methods and devices for cutting tissue at a vascular location|
|US8246641||7 Nov 2007||21 Aug 2012||Cook Medical Technolgies, LLC||Thrombus removal device|
|US8273100||31 Jul 2003||25 Sep 2012||Microvention, Inc.||Three element coaxial vaso-occlusive device|
|US8277468||24 Nov 2010||2 Oct 2012||Ethicon Endo-Surgery, Inc.||Tissue reconfiguration|
|US8287554||15 May 2003||16 Oct 2012||Ethicon Endo-Surgery, Inc.||Method and devices for tissue reconfiguration|
|US8328829||2 Nov 2007||11 Dec 2012||Covidien Lp||High capacity debulking catheter with razor edge cutting window|
|US8361096||19 Sep 2011||29 Jan 2013||Boston Scientific Scimed, Inc.||Cutting balloon catheter having flexible atherotomes|
|US8414543||23 Aug 2010||9 Apr 2013||Rex Medical, L.P.||Rotational thrombectomy wire with blocking device|
|US8414604||13 Oct 2009||9 Apr 2013||Covidien Lp||Devices and methods for manipulating a catheter shaft|
|US8435218||9 Feb 2011||7 May 2013||Rex Medical, L.P.||Double balloon thrombectomy catheter|
|US8465511||19 Oct 2011||18 Jun 2013||Rex Medical, L.P.||Rotational thrombectomy wire|
|US8469979||22 Sep 2011||25 Jun 2013||Covidien Lp||High capacity debulking catheter with distal driven cutting wheel|
|US8496677||2 Dec 2010||30 Jul 2013||Covidien Lp||Methods and devices for cutting tissue|
|US8523899 *||22 Aug 2012||3 Sep 2013||Olympus Medical Systems Corp.||Treatment device for endoscope|
|US8574249||1 May 2012||5 Nov 2013||Covidien Lp||Easily cleaned atherectomy catheters and methods of use|
|US8579926||28 Nov 2011||12 Nov 2013||Covidien Lp||Plaque removal device with rotatable cutting element|
|US8597315||1 Jul 2010||3 Dec 2013||Covidien Lp||Atherectomy catheter with first and second imaging devices|
|US8608761||19 Jul 2012||17 Dec 2013||Cook Medical Technologies Llc||Thrombus removal device|
|US8617193||4 May 2012||31 Dec 2013||Boston Scientific Scimed, Inc.||Balloon catheter with improved pushability|
|US8663259||27 Apr 2011||4 Mar 2014||Rex Medical L.P.||Rotational thrombectomy wire|
|US8690903||19 Dec 2012||8 Apr 2014||Boston Scientific Scimed, Inc.||Cutting balloon catheter having flexible atherotomes|
|US8728089 *||28 Mar 2008||20 May 2014||Olympus Medical Systems Corp.||Endoscope treatment instrument|
|US8764779||23 Nov 2011||1 Jul 2014||Rex Medical, L.P.||Rotational thrombectomy wire|
|US8764788||20 Jun 2011||1 Jul 2014||Microvention, Inc.||Multi-layer coaxial vaso-occlusive device|
|US8784440||1 Dec 2008||22 Jul 2014||Covidien Lp||Methods and devices for cutting tissue|
|US8808186||10 Nov 2011||19 Aug 2014||Covidien Lp||Flexible debulking catheters with imaging and methods of use and manufacture|
|US8852216||23 Mar 2007||7 Oct 2014||Ethicon Endo-Surgery, Inc.||Tissue approximation methods|
|US8882796||24 Aug 2012||11 Nov 2014||Microvention, Inc.||Three element coaxial vaso-occlusive device|
|US8911459||28 Jun 2012||16 Dec 2014||Covidien Lp||Debulking catheters and methods|
|US8920450||27 Oct 2011||30 Dec 2014||Covidien Lp||Material removal device and method of use|
|US8920451 *||12 Oct 2012||30 Dec 2014||Cook Medical Technologies Llc||Device and method for removing tissue inside a body vessel|
|US8945047||20 Jul 2009||3 Feb 2015||Boston Scientific Scimed, Inc.||Traction balloon|
|US8961546||17 Jul 2012||24 Feb 2015||Covidien Lp||Methods and devices for cutting tissue at a vascular location|
|US8992717||30 Aug 2012||31 Mar 2015||Covidien Lp||Catheter with helical drive shaft and methods of manufacture|
|US8998937||28 Apr 2009||7 Apr 2015||Covidien Lp||Methods and devices for cutting tissue|
|US9017294||9 Mar 2013||28 Apr 2015||Rex Medical, L.P.||Rotational thrombectomy wire with blocking device|
|US9017352 *||7 Feb 2013||28 Apr 2015||Cook Medical Technologies Llc||Helical fibrin removal tool|
|US9017353||20 Jan 2014||28 Apr 2015||Boston Scientific Scimed, Inc.||Cutting balloon catheter having flexible atherotomes|
|US9023070||26 Apr 2012||5 May 2015||Rex Medical, L.P.||Rotational thrombectomy wire coupler|
|US9028512||18 Sep 2012||12 May 2015||Covidien Lp||Material removal device having improved material capture efficiency and methods of use|
|US9114200||24 Sep 2010||25 Aug 2015||Microvention, Inc.||Injectable hydrogel filaments for biomedical uses|
|US9119662||14 Jun 2011||1 Sep 2015||Covidien Lp||Material removal device and method of use|
|US9192406||15 Mar 2013||24 Nov 2015||Covidien Lp||Method for manipulating catheter shaft|
|US9220530||27 Sep 2013||29 Dec 2015||Covidien Lp||Easily cleaned atherectomy catheters and methods of use|
|US9241733||10 Jun 2013||26 Jan 2016||Covidien Lp||Debulking catheter|
|US9259228||18 Jan 2013||16 Feb 2016||Microvention, Inc.||Embolization device constructed from expansile polymer|
|US9282992||1 Jun 2014||15 Mar 2016||Rex Medical, L.P.||Rotational thrombectomy wire|
|US9326789||13 Jun 2014||3 May 2016||Covidien Lp||Flexible debulking catheters with imaging and methods of use and manufacture|
|US9339282||6 Mar 2013||17 May 2016||Cook Medical Technologies Llc||Auger guidewire|
|US9345509 *||20 Dec 2013||24 May 2016||Baylis Medical Company Inc.||Guide-wire dilation device for facilitation of lesion crossing|
|US9381278||18 Mar 2015||5 Jul 2016||Microvention, Inc.||Embolic devices|
|US9445834||19 May 2014||20 Sep 2016||Covidien Lp||Methods and devices for cutting tissue|
|US9451963||19 Jul 2012||27 Sep 2016||Microvention, Inc.||Embolization device constructed from expansile polymer|
|US9456823||18 Apr 2012||4 Oct 2016||Terumo Corporation||Embolic devices|
|US9456843||3 Feb 2014||4 Oct 2016||Covidien Lp||Tissue-removing catheter including angular displacement sensor|
|US9474543||2 Jun 2013||25 Oct 2016||Argon Medical Devices, Inc.||Rotational thrombectomy wire|
|US9486221||21 May 2013||8 Nov 2016||Microvision, Inc.||Hydrogel filaments for biomedical uses|
|US9486237||12 Jul 2013||8 Nov 2016||Covidien Lp||Methods and devices for cutting tissue|
|US9526519||3 Feb 2014||27 Dec 2016||Covidien Lp||Tissue-removing catheter with improved angular tissue-removing positioning within body lumen|
|US9532799||13 Mar 2015||3 Jan 2017||Covidien Lp||Method and devices for cutting tissue|
|US9532844||13 Sep 2013||3 Jan 2017||Covidien Lp||Cleaning device for medical instrument and method of use|
|US9579157||13 Sep 2013||28 Feb 2017||Covidien Lp||Cleaning device for medical instrument and method of use|
|US9597110||8 Nov 2013||21 Mar 2017||Covidien Lp||Tissue-removing catheter including operational control mechanism|
|US9603619||27 Mar 2015||28 Mar 2017||Boston Scientific Scimed, Inc.||Cutting balloon catheter having flexible atherotomes|
|US9615850||25 Nov 2013||11 Apr 2017||Covidien Lp||Atherectomy catheter with aligned imager|
|US20020077648 *||31 Jan 2002||20 Jun 2002||Rubicor Medical, Inc.||Excisional biopsy devices and methods|
|US20020188307 *||19 Jul 2002||12 Dec 2002||Rafael Pintor||Neuro thrombectomy catheter|
|US20020193816 *||16 Aug 2002||19 Dec 2002||Ndo Surgical, Inc., A Delaware Corporation||Tissue reconfiguration|
|US20030037570 *||24 Jun 2002||27 Feb 2003||Sklyarevich Vladislav E.||Method for the rapid thermal treatment of glass and glass-like materials using microwave radiation|
|US20030208119 *||27 May 2003||6 Nov 2003||Crowley Robert J.||Medical imaging device|
|US20030216761 *||17 Jun 2003||20 Nov 2003||Samuel Shiber||Guidewire system|
|US20040006338 *||16 Oct 2002||8 Jan 2004||Rubicor Medical, Inc.||Methods and devices for cutting and collecting soft tissue|
|US20040006355 *||3 Jul 2002||8 Jan 2004||Rubicor Medical, Inc.||Methods and devices for cutting and collecting soft tissue|
|US20040006362 *||2 Jul 2002||8 Jan 2004||Dean Schaefer||Uniaxial multifilar vaso-occlusive device with high stretch resistance and low buckling strength|
|US20040006363 *||12 Nov 2002||8 Jan 2004||Dean Schaefer||Coaxial stretch-resistant vaso-occlusive device|
|US20040077971 *||16 Oct 2002||22 Apr 2004||Rubicor Medical, Inc.||Devices and methods for performing procedures on a breast|
|US20040087872 *||6 Nov 2002||6 May 2004||Rubicor Medical, Inc.||Excisional devices having selective cutting and atraumatic configurations and methods of using same|
|US20040098028 *||31 Jul 2003||20 May 2004||George Martinez||Three element coaxial vaso-occlusive device|
|US20040176789 *||8 Mar 2004||9 Sep 2004||Rubicor Medical, Inc.||Excisional biopsy devices and methods|
|US20040193184 *||8 Apr 2004||30 Sep 2004||Ndo Surgical, Inc., A Massachusetts Corporation||Methods and devices for tissue reconfiguration|
|US20040193194 *||8 Apr 2004||30 Sep 2004||Ndo Surgical, Inc., A Massachusetts Corporation||Tissue reconfiguration|
|US20040243156 *||29 May 2003||2 Dec 2004||Scimed Life Systems, Inc.||Cutting balloon catheter with improved balloon configuration|
|US20040255739 *||18 Jun 2003||23 Dec 2004||Rubicor Medical, Inc.||Methods and devices for cutting and collecting soft tissue|
|US20050027309 *||9 Sep 2004||3 Feb 2005||Samuel Shiber||Guidewire system|
|US20050033225 *||8 Aug 2003||10 Feb 2005||Scimed Life Systems, Inc.||Catheter shaft for regulation of inflation and deflation|
|US20050038383 *||14 Aug 2003||17 Feb 2005||Scimed Life Systems, Inc.||Catheter having a cutting balloon including multiple cavities or multiple channels|
|US20050119652 *||20 Aug 2004||2 Jun 2005||Rubicor Medical, Inc.||Devices and methods for performing procedures on a breast|
|US20050124986 *||9 Dec 2003||9 Jun 2005||Rubicor Medical, Inc.||Suction sleeve and interventional devices having such a suction sleeve|
|US20050143768 *||3 Mar 2005||30 Jun 2005||Samuel Shiber||Sleeved guidewire system method of use|
|US20050171572 *||24 Mar 2005||4 Aug 2005||Microvention, Inc.||Multi-layer coaxial vaso-occlusive device|
|US20050177073 *||1 Apr 2005||11 Aug 2005||Samuel Shiber||Guidewire system with a deflectable distal tip|
|US20050182339 *||26 Jan 2005||18 Aug 2005||Roberta Lee||Excisional biopsy devices and methods|
|US20050222521 *||6 Jun 2005||6 Oct 2005||Rubicor Medical, Inc.||Devices and methods for performing procedures on a breast|
|US20050228343 *||8 Apr 2004||13 Oct 2005||Scimed Life Systems, Inc.||Cutting balloon catheter and method for blade mounting|
|US20060100480 *||19 Dec 2005||11 May 2006||Usgi Medical Inc.||Apparatus and methods for achieving endoluminal access|
|US20060106407 *||20 Dec 2004||18 May 2006||Mcguckin James F Jr||Rotational thrombectomy wire|
|US20060224083 *||25 May 2006||5 Oct 2006||Rubicor Medical, Inc.||Methods and devices for cutting and collecting soft tissue|
|US20060229650 *||28 Mar 2006||12 Oct 2006||Rubicor Medical, Inc.||Methods and devices for cutting and collecting soft tissue|
|US20070010840 *||18 May 2006||11 Jan 2007||Fox Hollow Technologies, Inc.||Methods and devices for cutting tissue at a vascular location|
|US20070038225 *||11 Aug 2006||15 Feb 2007||Cook Incorporated||Thrombus removal device|
|US20070149951 *||27 Dec 2005||28 Jun 2007||Mina Wu||Variable stiffness guidewire|
|US20070197934 *||26 Apr 2007||23 Aug 2007||Rubicor Medical, Inc.||Devices and methods for performing procedures on a breast|
|US20070203427 *||26 Apr 2007||30 Aug 2007||Rubicor Medical, Inc.||Devices and methods for performing procedures on a breast|
|US20070203428 *||26 Apr 2007||30 Aug 2007||Rubicor Medical, Inc.||Devices and methods for performing procedures on a breast|
|US20070203513 *||30 Apr 2007||30 Aug 2007||Rubicor Medical, Inc.||Methods and devices for cutting and collecting soft tissue|
|US20070276419 *||26 May 2006||29 Nov 2007||Fox Hollow Technologies, Inc.||Methods and devices for rotating an active element and an energy emitter on a catheter|
|US20080125798 *||7 Nov 2007||29 May 2008||Cook Incorporated||Thrombus removal device|
|US20090247822 *||28 Mar 2008||1 Oct 2009||Olympus Medical Systems Corp.||Endoscope treatment instrument|
|US20090299394 *||28 Apr 2009||3 Dec 2009||Fox Hollow Technologies, Inc.||Methods and devices for cutting tissue|
|US20100022943 *||25 Jul 2008||28 Jan 2010||Medtronic Vascular, Inc.||Hydrodynamic Thrombectomy Catheter|
|US20100130996 *||13 Oct 2009||27 May 2010||Fox Hollow Technologies, Inc.||Devices and methods for manipulating a catheter shaft|
|US20100198240 *||9 Apr 2010||5 Aug 2010||Fox Hollow Technologies, Inc.||Debulking catheters and methods|
|US20100292721 *||14 May 2010||18 Nov 2010||Fox Hollow Technologies, Inc.||Easily cleaned atherectomy catheters and methods of use|
|US20100298850 *||1 Jul 2010||25 Nov 2010||Fox Hollow Technologies, Inc.||Atherectomy catheter with aligned imager|
|US20110130777 *||2 Dec 2010||2 Jun 2011||Fox Hollow Technologies, Inc.||Methods and devices for cutting tissue|
|US20110144673 *||9 Dec 2010||16 Jun 2011||Fox Hollow Technologies, Inc.||Material removal device having improved material capture efficiency and methods of use|
|US20110184455 *||25 Oct 2010||28 Jul 2011||Microvention, Inc.||Embolization Device Constructed From Expansile Polymer|
|US20110212178 *||24 Sep 2010||1 Sep 2011||Microvention, Inc.||Injectable Hydrogel Filaments For Biomedical Uses|
|US20120316543 *||22 Aug 2012||13 Dec 2012||Olympus Medical Systems Corp.||Treatment device for endoscope|
|US20140107678 *||7 Feb 2013||17 Apr 2014||Cook Medical Technologies Llc||Helical fibrin removal tool|
|US20140107681 *||20 Dec 2013||17 Apr 2014||Baylis Medical Company Inc.||Guide-Wire Dilation Device for Facilitation of Lesion Crossing|
|US20140107693 *||12 Oct 2012||17 Apr 2014||Cook Medical Technologies Llc||Device and method for removing tissue inside a body vessel|
|USRE36764 *||7 Jun 1995||4 Jul 2000||Nadim M. Zacca||Expandable tip atherectomy method and apparatus|
|DE3931350A1 *||20 Sep 1989||28 Mar 1991||Kaltenbach Martin||Fuehrungshuelse zum einfuehren von kathetern|
|EP1447052A3 *||22 Jun 2000||20 Oct 2004||NDO Surgical, Inc.||Gerd treatment apparatus and method|
|EP1658812A1 *||22 Jun 2000||24 May 2006||NDO Surgical, Inc.||Tissue reconfiguration|
|WO1989000835A1 *||17 May 1988||9 Feb 1989||Husted Royce Hill||Catheter with rotatable annular cutter|
|U.S. Classification||600/570, 606/159|
|International Classification||A61B10/00, A61B17/00, A61B10/02, A61M23/00, A61B10/04|
|Cooperative Classification||A61B2017/00685, A61B10/04|