US3675651A - Fluid-powered applicator for medicaments - Google Patents

Fluid-powered applicator for medicaments Download PDF

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US3675651A
US3675651A US14027A US3675651DA US3675651A US 3675651 A US3675651 A US 3675651A US 14027 A US14027 A US 14027A US 3675651D A US3675651D A US 3675651DA US 3675651 A US3675651 A US 3675651A
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medicament
cylinder
container
pressure
inlet
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Louis C Meyer
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/204—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically connected to external reservoirs for multiple refilling

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  • a power-actuated medicament applicator device includes a pressure cylinder and an injection needle or like applicator tool with a piston portion worked by pressure in the cylinder to drive the needle into the skin and then force a quantity of medicament carried in an accompanying container through the piston.
  • the piston is carried in a normally retracted position in the cylinder and will extend through a restricted opening in an end wall thereof.
  • the container for the medicament is located adjacent the cylinder and is carried in a rupturable ampule made of a flexible material. Flow passages between the pressure cylinder and container are arranged so that once the piston has moved to its extended position the container is pressurized to compres the ampule and medicament is forced from the container and through the needle or other applicator tool.
  • This invention relates to medicament applicators and more particularly to fluid-powered applicator apparatus for the controlled application of medicaments.
  • l-[ypodermic needles and various forms of applicator apparatus have heretofore been used for applying medicaments.
  • Previously known injection devices for the most part have been manually actuated and generally comprised a cylindrical housing, a barrel having a needle mounted at one end and a hand-actuated piston to force the medicament therein through the needle.
  • l-lennetically sealed ampules containing medicaments have been used to preserve strength and avoid contamination.
  • the hand or manually operated syringes are satisfactory for some applications but, as will be appreciated from the foregoing, a fluid-powered injection apparatus for projecting the needle and forcing the medicament lends itself to faster and more effective injections.
  • Another object of this invention is to provide novel and improved fluid-powered injection apparatus with a replaceable injection unit including a sterilized needle and a measured amount of medicament in a sealed ampule to be injected.
  • a further object of this invention is to provide an improved power-operated injection device characterized by successively driving the needle into the skin and then positively forcing the medicament from an ampule into the body through the needie.
  • an injection device which includes a medicament container with a rupturable ampule of medicament and a pressure cylinder containing an injection needle with a piston portion arranged to be driven through the end of the cylinder into the skin.
  • Flow passages at particular locations couple the interior of the medicament container to the interior of the cylinder so that the pressure in the cylinder may be used to force the medicament through the needle.
  • the medicament container, cylinder, ampule and needle are constructed as a replaceable or disposable unit which is arranged for releasable coupling to a control valve unit which may be permanently connected to a source of fluid under pressure.
  • FIG. 1 is a vertical sectional view through injection apparatus embodying features of the present invention
  • FIG. 2 is a sectional view taken along lines 2-2 of FIG. 1;
  • FIG. 3 is a sectional view taken along lines 3-3 of FIG. 1.
  • the injection apparatus shown broadly stated comprises an injection unit 11 which is supported by and releasably coupled to a control valve tool or unit 12 for regulating the fluid pressure into the injection unit 11 from a supply line 13 which, for example, leads from a compressed air source or other source of fluid under pressure, not shown.
  • the injection unit 1 1 is constructed to be used as a replaceable unit which is to be used only once and then replaced.
  • the apparatus described herein is particularly suited for air pressure actuation.
  • Unit ll comprises a cylindrical medicament container 15 and a pressure cylinder 16 joined together in a juxtaposed relation with a common wall 17.
  • a pressure passage 18 and a return passage 19 are provided in the wall 17 at the forward end of the container so as to transfer the fluid pressure from the cylinder into the container and to pass medicament from the container in the sequence of operation as described more fully hereinafter.
  • a longitudinal groove 20 is provided in the wall of the container to pass air from passage 18 along one side of the ampule.
  • medicament refers to medicinal materials in a liquid or gas form including nitrogen, narcotics and the like which may be injected.
  • a hollow injection needle 21 having a piston portion 22 at one end is carried in the cylinder 16 for movement from the retracted position wholly within the cylinder, as shown in full, through a restricted opening 23 in the discharge end of the cylinder to an extended position in which it will penetrate the skin, as shown in dashed lines 21a, under the influence of the fluid pressure applied to the cylinder 16.
  • the discharge end of the cylinder may be adapted for attachment of fittings commonly used for application of the medicament, such as, for use in skin treatment.
  • the piston portion 22 has a pair of axially spaced annular seal members or O-rings 25 and 26, and a radial passage 27 in the cylinder 16 is aligned between the rings in the extended position of the needle to vent any fluid under pressure which may leak past the inner seal 25.
  • the piston portion 22 also includes a passage defined by a radial bore 28 which communicates with the hollow interior of the needle from an external annular groove 29 at its upper end to permit the medicament to flow into the interior of the needle regardless of flte circumferential position of the needle relative to the cylinder.
  • the forward or outer end portion 31 of the piston is tapered so as to seal against a complementary tapered.
  • portion 32 within the cylinder in its extended position so as to provide a stop for the needle and, as will be observed with the dashed lines, the annular groove 29 aligns with the discharge passage 19 so that the medicament will be discharged from the container into the needle.
  • the container 15 is formed to receive a flexible ampule 3S and has a concave bottom portion 150.
  • the ampule 35 is made of a plastic or like material containing a medicament 36 to be injected into the body by the needle.
  • the bottom of the ampule terminates above the concave portion to provide a space therebetween and the forward end of the container is welded to the inner surfaces of the container.
  • a sharp pin 38 is mounted in the concave bottom portion 15a so that when fluid under pressure is applied to the interior of the container it is forced into the concave portion and punctured by the pin 38.
  • a cap 39 is secured across the rear end of the container 15 after the ampule has been inserted and is held in place by means of electronic welding or the like.
  • the control valve unit 12 includes an open cylindrical housing 42 at one end of a valve body 43, and the supply line 13 is connected to the opposite end of the body 43.
  • the housing 42 defines an enlarged cylindrical shroud 45 projecting forwardly from a base portion 44 and which forms an extension of a hollow sleeve 46, the latter being offset from the center of the base and threaded at one end into the end of the valve body 43.
  • the sleeve is in communication with the interior of the housing 42 for slidable insertion of the end of the pressure cylinder 16 into sealed relation to a shoulder surface at the forward end of a reduced axial bore 63 which is provided in the threaded end.
  • a nipple 40 made of a flexible material such as rubber and having an enlarged head is provided on the outer surface of the end cap 39.
  • Nipple 40 forcibly inserts into an aperture 41 in the center of base 44 when units 11 and 12 are brought together and removal of unit 11 is accomplished by forcing the nipple back through the aperture 41.
  • An alignment key 51 on the container slides into a complementary groove 52 in the shroud portion to properly align the container and piston with respect to the housing 42.
  • the valve body 43 includes a central bore 62 with an inclined intermediate passage 64 opening through a side of the valve body.
  • a hollow fitting 65 is threaded into the end of the bore 62, and an elongated cylinder 66 is threaded into the intermediate passage so as to be inclined forwardly on an angle with the valve. This forward inclination permits the unit to be held in the palm of the hand of the user and the plunger to be readily depressed a selected amount by use of the thumb or forefinger for controlled application of medicaments.
  • a valve element 67 is disposed in the inclined passage 64 and is normally held against a tapered valve seat 68 at the end of the cylinder 66 by a spring member 69 which abuts against a seat within the fitting 65 and against the enlarged head of the valve element so as to bias the valve to a normally closed position.
  • a plunger 71 is slidable through the cylinder 66 to engage the head of the valve element 67, and a cap 72 is threaded onto the end of the cylinder 66 to retain the plunger therein.
  • a reduced end of the plunger extends through an aperture in the cap and is provided with a flat head 73 to depress the plunger downwardly against the valve element 67 to open the valve against the urging of the spring 69.
  • Fluid under pressure is then free to flow past the valve element through a narrow aperture 74 in the cylinder 66 into the outlet passage 63 which will then pass the fluid under pressure into the cylinder against the inner end of the piston.
  • the needle is driven through the discharge end of the cylinder into the skin until the piston has cleared the port 18, after which the fluid is passed into the container along groove to act across the end of the ampule adjacent to the base 44.
  • the ampule is compressed, as shown in dashed lines 35a, whereby to force the ampule against pin 38 to penetrate same and the medicament is then forced through passage 19 and through the needle.
  • the unit will sequentially drive the needle and automatically inject the medicament into the body. Close regulation of the amount and duration of injection is possible by the pressure applied to the plunger 71 via cap 73.
  • unit 11 Once unit 11 has been used it is removed from unit 12 and replaced with another unit 11 with the required medicament.
  • the medicament can be dispensed in a desired quantity so as to eliminate the possibility of unauthorized use of a portion of the unused medicament.
  • the device is readily adaptable for use in dispensing medicaments from the ampule into a hollow applicator tool positioned at the discharge end of the cylinder in place of an injection needle.
  • the tool may be pressed against the skin and liquid nitrogen selectively released from the ampule in the manner described by driving the piston forwardly to pass fluid under pressure into the container so that the medicament can be forced through the needle into the interior of the tool.
  • a pressure cylinder coupled to the medicament container including a pressure inlet end and an applicator end, with an inlet flow passage between said container and cylinder arranged to admit fluid under pressure from the cylinder into the medicament container and an outlet flow passage between the container and cylinder, means separating the medicament from the pressurized fluid and preventing the medicament from flowing through the outlet passage until the pressure is applied and a piston member movable through said pressure cylinder in response to fluid under pressure delivered into said pressure inlet, said piston member being movable from a retracted position closing said inlet flow passage to an extended position opening said inlet flow passage and said outlet passage into said cylinder via said piston member, the pressure in the cylinder positively forcing the medicament from the container via said inlet and outlet flow passages whereby to discharge the medicament from the container through the applicator end of said pressure cylinder.
  • inlet flow passage comprises an opening through said common wall portion disposed rearwardly of the piston member when moved to its extended position to pressurize the container.
  • a medicament applicator as set forth in claim 3 further including an injection needle located at the leading end of said piston member movable through the applicator end of said cylinder, and said outlet flow passage comprises an opening through said common wall portion which aligns with a passage in the side of the piston member opening to the interior of said needle.
  • said means separating the medicament from the pressurized fluid comprises a rupturable ampule made of a flexible material in said container enclosing said medicament.
  • a medicament applicator as set forth in claim 8 including a passage in the cylinder between said sealing rings in their extended position to vent the pressure in the cylinder to the atmosphere if one of the rings should fail.
  • a cartridge including a medicament container having a rupturable ampule of medicament to be injected and a fluid pressure cylinder with a common wall joining said container and cylinder, said cylinder having a pressure inlet, an inlet flow passage in said common wall to admit fluid under pressure from the cylinder into the interior of the container and an outlet flow passage for the flow of medicament from the medicament container through the cylinder, the pressure in the cylinder positively forcing the medicament from the ampule and container via said inlet and outlet flow passages,
  • a hollow injection needle having a piston portion in the pressure cylinder movable in response to fluid under pres sure delivered into said pressure inlet, said piston portion being movable from a retracted to an extended position and after being extended to open said inlet flow passage and said outlet flow passage into said cylinder and position an inlet of the needle in communication with the container for said ampule, and
  • a flow-control valve releasably coupled to the cartridge to selectively admit fluid under pressure from the source into the pressure cylinder into said pressure inlet whereby to successively drive the needle to penetrate the skin of a body and regulate the application of the medicament through the needle into the body.
  • a fluid-powered applicator tool as set forth in claim 10 including a housing extending beyond one end of the valve into which the cartridge is releasably inserted.
  • said medicament container has an end cap having a flexible nipple adapted to be forced through an aperture at the base of the housing to releasably secure the cartridge to the housing.
  • a pneumatic-powered injection device having a source of fluid under pressure comprising a disposable injection cartridge unit including a medicament container with a rupturable ampule of medicament to be injected and a pressure cylinder having a pressure inlet with a hollow injection needle having a piston porsaid extended position, said unit including means to selection, said container and cylinder being a part of a single tively rupture said ampule at said outlet passage, and body joined by a common wall having an inlet pressure a flow-control valve assembly coupled to the cartridge unit passage to pressurize the container from the cylinder and having a housing at one end for releasable insertion of the an outlet flow passage to pass medicament from h 5 cartridge unit to selectively admit air under pressure into tainer into the pressure cylinder, said piston portion being y f Via said N inlet f nowadays

Abstract

A power-actuated medicament applicator device includes a pressure cylinder and an injection needle or like applicator tool with a piston portion worked by pressure in the cylinder to drive the needle into the skin and then force a quantity of medicament carried in an accompanying container through the piston. The piston is carried in a normally retracted position in the cylinder and will extend through a restricted opening in an end wall thereof. The container for the medicament is located adjacent the cylinder and is carried in a rupturable ampule made of a flexible material. Flow passages between the pressure cylinder and container are arranged so that once the piston has moved to its extended position the container is pressurized to compress the ampule and medicament is forced from the container and through the needle or other applicator tool.

Description

United States Patent Meyer [54] FLUID-POWERED APPLICATOR FOR MEDICAMENTS [72] Inventor: Louis C. Meyer, Box 434 Rte. '1, Morrison, Colo. 80465 [22] Filed: Feb. 25, 1970 [21] Appl. No.: 14,027
521 user ..l28/215 s11 lnt.Cl. ..A6lm5/00 [$8] FieldoISearch ..12s/21sA,2|so,2|sc,21soA.
128/173 H, 215, 218 F. 218 D. 223; 222/80, 320.
[ 51 July 11,1972
Primary Examiner-Richard A. Gaudet Assistant Examiner-.1. B. Mitchell At!0meyRcilly and Lewis ABSTRACT A power-actuated medicament applicator device includes a pressure cylinder and an injection needle or like applicator tool with a piston portion worked by pressure in the cylinder to drive the needle into the skin and then force a quantity of medicament carried in an accompanying container through the piston. The piston is carried in a normally retracted position in the cylinder and will extend through a restricted opening in an end wall thereof. The container for the medicament is located adjacent the cylinder and is carried in a rupturable ampule made of a flexible material. Flow passages between the pressure cylinder and container are arranged so that once the piston has moved to its extended position the container is pressurized to compres the ampule and medicament is forced from the container and through the needle or other applicator tool.
14Claim3DrawingFlgures PATENTEnJuu 1 1972 IN VE N TOR LOUIS YER ATTORNEYS FLUID-POWERED APPLICATOR FOR MEDICAMENTS This invention relates to medicament applicators and more particularly to fluid-powered applicator apparatus for the controlled application of medicaments.
l-[ypodermic needles and various forms of applicator apparatus have heretofore been used for applying medicaments. Previously known injection devices for the most part have been manually actuated and generally comprised a cylindrical housing, a barrel having a needle mounted at one end and a hand-actuated piston to force the medicament therein through the needle. l-lennetically sealed ampules containing medicaments have been used to preserve strength and avoid contamination. The hand or manually operated syringes are satisfactory for some applications but, as will be appreciated from the foregoing, a fluid-powered injection apparatus for projecting the needle and forcing the medicament lends itself to faster and more effective injections.
Accordingly, it is an object of this invention to provide a simple, durable and efficient fluid-powered applicator apparatus for injecting a variety of medicaments into the body or for the application of same to the skin.
Another object of this invention is to provide novel and improved fluid-powered injection apparatus with a replaceable injection unit including a sterilized needle and a measured amount of medicament in a sealed ampule to be injected.
A further object of this invention is to provide an improved power-operated injection device characterized by successively driving the needle into the skin and then positively forcing the medicament from an ampule into the body through the needie.
In accordance with the present invention, a preferred form of an injection device has been constructed which includes a medicament container with a rupturable ampule of medicament and a pressure cylinder containing an injection needle with a piston portion arranged to be driven through the end of the cylinder into the skin. Flow passages at particular locations couple the interior of the medicament container to the interior of the cylinder so that the pressure in the cylinder may be used to force the medicament through the needle. The medicament container, cylinder, ampule and needle are constructed as a replaceable or disposable unit which is arranged for releasable coupling to a control valve unit which may be permanently connected to a source of fluid under pressure.
Other objects, advantages and capabilities of the present invention will become more apparent as the description proceeds taken in conjunction with the accompanying drawings, in which:
FIG. 1 is a vertical sectional view through injection apparatus embodying features of the present invention;
FIG. 2 is a sectional view taken along lines 2-2 of FIG. 1; and
FIG. 3 is a sectional view taken along lines 3-3 of FIG. 1.
Referring now to the drawings, the injection apparatus shown broadly stated comprises an injection unit 11 which is supported by and releasably coupled to a control valve tool or unit 12 for regulating the fluid pressure into the injection unit 11 from a supply line 13 which, for example, leads from a compressed air source or other source of fluid under pressure, not shown. The injection unit 1 1 is constructed to be used as a replaceable unit which is to be used only once and then replaced. The apparatus described herein is particularly suited for air pressure actuation. Unit ll comprises a cylindrical medicament container 15 and a pressure cylinder 16 joined together in a juxtaposed relation with a common wall 17. A pressure passage 18 and a return passage 19 are provided in the wall 17 at the forward end of the container so as to transfer the fluid pressure from the cylinder into the container and to pass medicament from the container in the sequence of operation as described more fully hereinafter. A longitudinal groove 20 is provided in the wall of the container to pass air from passage 18 along one side of the ampule. The term medicament" as used herein refers to medicinal materials in a liquid or gas form including nitrogen, narcotics and the like which may be injected.
A hollow injection needle 21 having a piston portion 22 at one end is carried in the cylinder 16 for movement from the retracted position wholly within the cylinder, as shown in full, through a restricted opening 23 in the discharge end of the cylinder to an extended position in which it will penetrate the skin, as shown in dashed lines 21a, under the influence of the fluid pressure applied to the cylinder 16. The discharge end of the cylinder may be adapted for attachment of fittings commonly used for application of the medicament, such as, for use in skin treatment. The piston portion 22 has a pair of axially spaced annular seal members or O- rings 25 and 26, and a radial passage 27 in the cylinder 16 is aligned between the rings in the extended position of the needle to vent any fluid under pressure which may leak past the inner seal 25. This avoids introducing fluid under pressure into the body. The piston portion 22 also includes a passage defined by a radial bore 28 which communicates with the hollow interior of the needle from an external annular groove 29 at its upper end to permit the medicament to flow into the interior of the needle regardless of flte circumferential position of the needle relative to the cylinder. The forward or outer end portion 31 of the piston is tapered so as to seal against a complementary tapered. portion 32 within the cylinder in its extended position so as to provide a stop for the needle and, as will be observed with the dashed lines, the annular groove 29 aligns with the discharge passage 19 so that the medicament will be discharged from the container into the needle.
The container 15 is formed to receive a flexible ampule 3S and has a concave bottom portion 150. The ampule 35 is made of a plastic or like material containing a medicament 36 to be injected into the body by the needle. The bottom of the ampule terminates above the concave portion to provide a space therebetween and the forward end of the container is welded to the inner surfaces of the container. To rupture the ampule as required, a sharp pin 38 is mounted in the concave bottom portion 15a so that when fluid under pressure is applied to the interior of the container it is forced into the concave portion and punctured by the pin 38. A cap 39 is secured across the rear end of the container 15 after the ampule has been inserted and is held in place by means of electronic welding or the like.
The control valve unit 12 includes an open cylindrical housing 42 at one end of a valve body 43, and the supply line 13 is connected to the opposite end of the body 43. The housing 42 defines an enlarged cylindrical shroud 45 projecting forwardly from a base portion 44 and which forms an extension of a hollow sleeve 46, the latter being offset from the center of the base and threaded at one end into the end of the valve body 43. The sleeve is in communication with the interior of the housing 42 for slidable insertion of the end of the pressure cylinder 16 into sealed relation to a shoulder surface at the forward end of a reduced axial bore 63 which is provided in the threaded end.
To releasably hold unit 11 in the housing 42, a nipple 40 made of a flexible material such as rubber and having an enlarged head is provided on the outer surface of the end cap 39. Nipple 40 forcibly inserts into an aperture 41 in the center of base 44 when units 11 and 12 are brought together and removal of unit 11 is accomplished by forcing the nipple back through the aperture 41. An alignment key 51 on the container slides into a complementary groove 52 in the shroud portion to properly align the container and piston with respect to the housing 42.
The valve body 43 includes a central bore 62 with an inclined intermediate passage 64 opening through a side of the valve body. A hollow fitting 65 is threaded into the end of the bore 62, and an elongated cylinder 66 is threaded into the intermediate passage so as to be inclined forwardly on an angle with the valve. This forward inclination permits the unit to be held in the palm of the hand of the user and the plunger to be readily depressed a selected amount by use of the thumb or forefinger for controlled application of medicaments.
A valve element 67 is disposed in the inclined passage 64 and is normally held against a tapered valve seat 68 at the end of the cylinder 66 by a spring member 69 which abuts against a seat within the fitting 65 and against the enlarged head of the valve element so as to bias the valve to a normally closed position. A plunger 71 is slidable through the cylinder 66 to engage the head of the valve element 67, and a cap 72 is threaded onto the end of the cylinder 66 to retain the plunger therein. A reduced end of the plunger extends through an aperture in the cap and is provided with a flat head 73 to depress the plunger downwardly against the valve element 67 to open the valve against the urging of the spring 69. Fluid under pressure is then free to flow past the valve element through a narrow aperture 74 in the cylinder 66 into the outlet passage 63 which will then pass the fluid under pressure into the cylinder against the inner end of the piston. In rapid succession the needle is driven through the discharge end of the cylinder into the skin until the piston has cleared the port 18, after which the fluid is passed into the container along groove to act across the end of the ampule adjacent to the base 44. The ampule is compressed, as shown in dashed lines 35a, whereby to force the ampule against pin 38 to penetrate same and the medicament is then forced through passage 19 and through the needle.
Thus once the valve plunger has been depressed the unit will sequentially drive the needle and automatically inject the medicament into the body. Close regulation of the amount and duration of injection is possible by the pressure applied to the plunger 71 via cap 73.
Once unit 11 has been used it is removed from unit 12 and replaced with another unit 11 with the required medicament. One particular advantage of this arrangement is that the medicament can be dispensed in a desired quantity so as to eliminate the possibility of unauthorized use of a portion of the unused medicament. Another advantage is that the device is readily adaptable for use in dispensing medicaments from the ampule into a hollow applicator tool positioned at the discharge end of the cylinder in place of an injection needle. For example, in the treatment of skin cancer, the tool may be pressed against the skin and liquid nitrogen selectively released from the ampule in the manner described by driving the piston forwardly to pass fluid under pressure into the container so that the medicament can be forced through the needle into the interior of the tool.
While there has been shown and described a preferred form of the present invention as well as adaptations thereof to different uses, it is to be understood that various modifications and changes may be resorted to without departing from the spirit and scope of the present invention as defined in the appended claims.
What is claimed is:
1. In a medicament applicator operated by a source of fluid under pressure, the combination of a container having a medicament to be delivered,
a pressure cylinder coupled to the medicament container including a pressure inlet end and an applicator end, with an inlet flow passage between said container and cylinder arranged to admit fluid under pressure from the cylinder into the medicament container and an outlet flow passage between the container and cylinder, means separating the medicament from the pressurized fluid and preventing the medicament from flowing through the outlet passage until the pressure is applied and a piston member movable through said pressure cylinder in response to fluid under pressure delivered into said pressure inlet, said piston member being movable from a retracted position closing said inlet flow passage to an extended position opening said inlet flow passage and said outlet passage into said cylinder via said piston member, the pressure in the cylinder positively forcing the medicament from the container via said inlet and outlet flow passages whereby to discharge the medicament from the container through the applicator end of said pressure cylinder.
2. In a medicament applicator as set forth in claim I wherein said medicament container and pressure cylinder are a part of a single body and have a common wall portion.
3. In a medicament applicator as set forth in claim 2 wherein said inlet flow passage comprises an opening through said common wall portion disposed rearwardly of the piston member when moved to its extended position to pressurize the container.
4. In a medicament applicator as set forth in claim 3 further including an injection needle located at the leading end of said piston member movable through the applicator end of said cylinder, and said outlet flow passage comprises an opening through said common wall portion which aligns with a passage in the side of the piston member opening to the interior of said needle.
5. In a medicament applicator as set forth in claim 1 wherein said means separating the medicament from the pressurized fluid comprises a rupturable ampule made of a flexible material in said container enclosing said medicament.
6. in a medicament applicator as set forth in claim 5 including means in the container against which the ampule is forced to rupture said ampule.
7. In a medicament applicator as set forth in claim 5 wherein said container and cylinder are preloaded with said ampule and needle to provide a disposable injection unit.
8. In a medicament applicator as set forth in claim I wherein said piston member has spaced sealing rings to seal against pressure loss in the cylinder.
9. In a medicament applicator as set forth in claim 8 including a passage in the cylinder between said sealing rings in their extended position to vent the pressure in the cylinder to the atmosphere if one of the rings should fail.
10. In a fluid powered applicator tool having a source of fluid under pressure, the combination of a cartridge including a medicament container having a rupturable ampule of medicament to be injected and a fluid pressure cylinder with a common wall joining said container and cylinder, said cylinder having a pressure inlet, an inlet flow passage in said common wall to admit fluid under pressure from the cylinder into the interior of the container and an outlet flow passage for the flow of medicament from the medicament container through the cylinder, the pressure in the cylinder positively forcing the medicament from the ampule and container via said inlet and outlet flow passages,
a hollow injection needle having a piston portion in the pressure cylinder movable in response to fluid under pres sure delivered into said pressure inlet, said piston portion being movable from a retracted to an extended position and after being extended to open said inlet flow passage and said outlet flow passage into said cylinder and position an inlet of the needle in communication with the container for said ampule, and
a flow-control valve releasably coupled to the cartridge to selectively admit fluid under pressure from the source into the pressure cylinder into said pressure inlet whereby to successively drive the needle to penetrate the skin of a body and regulate the application of the medicament through the needle into the body.
II. In a fluid-powered applicator tool as set forth in claim 10 including a housing extending beyond one end of the valve into which the cartridge is releasably inserted.
12. In a fluid-powered applicator tool as set forth in claim 11 wherein said medicament container has an end cap having a flexible nipple adapted to be forced through an aperture at the base of the housing to releasably secure the cartridge to the housing.
13. In a fluid-powered applicator tool as set forth in claim 11 wherein said housing has an enlarged bore sized to slidably receive an end of the cylinder.
14. A pneumatic-powered injection device having a source of fluid under pressure comprising a disposable injection cartridge unit including a medicament container with a rupturable ampule of medicament to be injected and a pressure cylinder having a pressure inlet with a hollow injection needle having a piston porsaid extended position, said unit including means to selection, said container and cylinder being a part of a single tively rupture said ampule at said outlet passage, and body joined by a common wall having an inlet pressure a flow-control valve assembly coupled to the cartridge unit passage to pressurize the container from the cylinder and having a housing at one end for releasable insertion of the an outlet flow passage to pass medicament from h 5 cartridge unit to selectively admit air under pressure into tainer into the pressure cylinder, said piston portion being y f Via said N inlet f?! w succesmovable from a retracted position to an extended posily drive the new! the extend Pamon f p tion to open said inlet flow passage and said outlet flow the Inlet and out!" flow Passages to force medlcamem passage Said piston portion having a passage to pass through the needle under the regulation of the control medicament from the outlet flow passage into the needle 10 valvewhen advanced by fluid under pressure in the cylinder to

Claims (14)

1. In a medicament applicator operated by a source of fluid under pressure, the combination of a container having a medicament to be delivered, a pressure cylinder coupled to the medicament container including a pressure inlet end and an applicator end, with an inlet flow passage between said container and cylinder arranged to admit fluid under pressure from the cylinder into the medicament container and an outlet flow passage between the container and cylinder, means separating the medicament from the pressurized fluid and preventing the medicament from flowing through the outlet passage until the pressure is applied and a piston member movable through said pressure cylinder in response to fluid under pressure delivered into said pressure inlet, said piston member being movable from a retracted position closing said inlet flow passage to an extended position opening said inlet flow passage and said outlet passage into said cylinder via said piston member, the pressure in the cylinder positively forcing the medicament from the container via said inlet and outlet flow passages whereby to discharge the medicament from the container through the applicator end of said pressure cylinder.
2. In a medicament applicator as set forth in claim 1 wherein said medicament container and pressure cylinder are a part of a single body and have a common wall portion.
3. In a medicament applicator as set forth in claim 2 wherein said inlet flow passage comprises an opening through said common wall portion disposed rearwardly of the piston member when moved to its extended position to pressurize the container.
4. In a medicament applicator as set forth in claim 3 further including an injection needle located at the leading end of said piston member movable through the applicator end of said cylinder, and said outlet flow passage comprises an opening through said common wall portion which aligns with a passage in the side of the piston member opening to the interior of said needle.
5. In a medicament applicator as set forth in claim 1 wherein said means separating the medicament from the pressurized fluid comprises a rupturable ampule made of a flexible material in said container enclosing said medicament.
6. In a medicament applicator as set forth in claim 5 including means in the container against which the ampule is forced to rupture said ampule.
7. In a medicament applicator as set forth in claim 5 wherein said container and cylinder are preloaded with said ampule and needle to provide a disposable injection unit.
8. In a medicament applicator as set forth in claim 1 wherein said piston member has spaced sealing rings to seal against pressure loss in the cylinder.
9. In a medicament applicator as set forth in claim 8 including a passage in the cylinder between said sealing rings in their extended position to vent the pressure in the cylinder to the atmosphere if one of the rings should fail.
10. In a fluid powered applicator tool having a source of fluid under pressure, the combination of a cartridge including a medicament container having a rupturable ampule of medicament to be injected and a fluid pressure cylinder with a common wall joining said container and cylinder, said cylinder having a pressure inlet, an inlet flow passage in said common wall to admit fluid under pressure from the cylinder into the interior of the container and an outlet flow passage for the flow of medicament from the medicament container through the cylinder, the pressure in the cylinder positively forcing the medicament from the ampule and container via said inlet and outlet flow passages, a hollow injection needle having a piston portion in the pressure cylinder movable in response to fluid under pressure delivered into said pressure inlet, said piston portion being movable from a retracted to an extended position and after being extended to open said inlet flow passage and said outlet flow passage into said cylinder and position an inlet of the needle in communication with the container for said ampule, and a flow-control valve releasably coupled to the cartridge to selectively admit fluid under pressure from the source into the pressure cylinder into said pressure inlet whereby to successively drive the needle to penetrate the skin of a body and regulate the application of the medicament through the needle into the body.
11. In a fluid-powered applicator tool as set forth in claim 10 including a housing extending beyond one end of the valve into which the cartridge is releasably inserted.
12. In a fluid-powered applicator tool as set forth in claim 11 wherein said medicament container has an end cap having a flexible nipple adapted to be forced through an aperture at the base of the housing to releasably secure the cartridge to the housing.
13. In a fluid-powered applicator tool as set forth in claim 11 wherein said housing has an enlarged bore sized to slidably receive an end of the cylinder.
14. A pneumatic-powered injection device having a source of fluid under pressure comprising a disposable injection cartridge unit including a medicament container with a rupturable ampule of medicament to be injected and a pressure cylinder having a pressure inlet with a hollow injection needle having a piston portion, said container and cylinder being a part of a single body joined by a common wall having an inlet pressure passage to pressurize the container from the cylinder and an outlet flow passage to pass medicament from the container into the pressure cylinder, said piston portion being movable from a retracted position to an extended position to open said inlet flow passage and said outlet flow passage, said piston portion having a passage to pass medicament from the outlet flow passage into the needle when advanced by fluid under pressure in the cylinder to said extended position, said unit including means to selectively rupture said ampule at said outlet passage, and a flow-control valve assembly coupled to the cartridge unit having a housing at one end for releasable insertion of the cartridge unit to selectively admit air under pressure into said cylinder via said pressure inlet whereby to successively drive the needle to the extended position and open the inlet and outlet flow passages to force medicament through the needle under the regulation of the control valve.
US14027A 1970-02-25 1970-02-25 Fluid-powered applicator for medicaments Expired - Lifetime US3675651A (en)

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4381006A (en) * 1980-11-10 1983-04-26 Abbott Laboratories Continuous low flow rate fluid dispenser
EP0080112A2 (en) * 1981-11-24 1983-06-01 Coopers Animal Health New Zealand Limited Improvements in and relating to applicators
US4578061A (en) * 1980-10-28 1986-03-25 Lemelson Jerome H Injection catheter and method
US5312353A (en) * 1993-03-24 1994-05-17 Boggess Gregory D Modular poultry automatic vaccine injection and spray apparatus
US5612050A (en) * 1993-03-23 1997-03-18 Focal, Inc. Apparatus and method for local application of polymeric material to tissue
US20020004639A1 (en) * 2000-01-07 2002-01-10 Willis John P. Injection device
US20020151842A1 (en) * 2000-11-30 2002-10-17 Gonnelli Robert R. Injection systems
US6468520B1 (en) 1993-03-23 2002-10-22 Focal, Inc. Apparatus and method for local application of polymeric material to tissue
US20040249339A1 (en) * 1998-12-18 2004-12-09 Biovalve Technologies, Inc. Injection devices
US20060009737A1 (en) * 2004-07-12 2006-01-12 Whiting James S Methods and devices for transseptal access
US20130006216A1 (en) * 2010-02-01 2013-01-03 Margaret Taylor Low dose prefilled drug delivery device and method

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2693186A (en) * 1953-05-18 1954-11-02 William M Riker Disposable hypodermic injection syringe
US3051173A (en) * 1960-05-12 1962-08-28 Alvin P Johnson Veterinary hypodermic syringe
US3057349A (en) * 1959-12-14 1962-10-09 Ismach Aaron Multi-dose jet injection device
US3461867A (en) * 1966-03-14 1969-08-19 Mizzy Inc Needleless injector

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2693186A (en) * 1953-05-18 1954-11-02 William M Riker Disposable hypodermic injection syringe
US3057349A (en) * 1959-12-14 1962-10-09 Ismach Aaron Multi-dose jet injection device
US3051173A (en) * 1960-05-12 1962-08-28 Alvin P Johnson Veterinary hypodermic syringe
US3461867A (en) * 1966-03-14 1969-08-19 Mizzy Inc Needleless injector

Cited By (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578061A (en) * 1980-10-28 1986-03-25 Lemelson Jerome H Injection catheter and method
US4381006A (en) * 1980-11-10 1983-04-26 Abbott Laboratories Continuous low flow rate fluid dispenser
EP0080112A2 (en) * 1981-11-24 1983-06-01 Coopers Animal Health New Zealand Limited Improvements in and relating to applicators
EP0080112A3 (en) * 1981-11-24 1983-07-06 Wellcome New Zealand Limited Improvements in and relating to applicators
US5698189A (en) * 1993-03-23 1997-12-16 Focal, Inc. Method for local application of polymeric material to tissue
US5612050A (en) * 1993-03-23 1997-03-18 Focal, Inc. Apparatus and method for local application of polymeric material to tissue
US7037490B2 (en) 1993-03-23 2006-05-02 Genzyme Corporation Apparatus and method for local application of polymeric material to tissue
US6468520B1 (en) 1993-03-23 2002-10-22 Focal, Inc. Apparatus and method for local application of polymeric material to tissue
US6960340B2 (en) 1993-03-23 2005-11-01 Focal, Inc Apparatus and method for local application of polymeric material to tissue
US20040131554A1 (en) * 1993-03-23 2004-07-08 Focal, Inc. Apparatus and method for local application of polymeric material to tissue
US5312353A (en) * 1993-03-24 1994-05-17 Boggess Gregory D Modular poultry automatic vaccine injection and spray apparatus
US20040249339A1 (en) * 1998-12-18 2004-12-09 Biovalve Technologies, Inc. Injection devices
US7740607B2 (en) 1998-12-18 2010-06-22 Valeritas, Inc. Modular units for use in an injection device
US6960184B2 (en) 1998-12-18 2005-11-01 Biovalve Technologies, Inc. Injection devices
US20050154350A1 (en) * 1998-12-18 2005-07-14 Biovalve Technologies, Inc. Injection devices
US20040220525A1 (en) * 2000-01-07 2004-11-04 Willis John P Injection device
US20020004639A1 (en) * 2000-01-07 2002-01-10 Willis John P. Injection device
US7806867B2 (en) 2000-01-07 2010-10-05 Valeritas, Inc. Injection device
US20110172634A1 (en) * 2000-11-30 2011-07-14 Valeritas, Inc. Injection systems
US20020161329A1 (en) * 2000-11-30 2002-10-31 Gonnelli Robert R. Injection systems
US20020156418A1 (en) * 2000-11-30 2002-10-24 Gonnelli Robert R. Injection systems
US20030149397A9 (en) * 2000-11-30 2003-08-07 Gonnelli Robert R. Injection systems
US20020151842A1 (en) * 2000-11-30 2002-10-17 Gonnelli Robert R. Injection systems
US7150409B2 (en) 2000-11-30 2006-12-19 Biovalve Technologies, Inc. Injection systems
US8500681B2 (en) 2000-11-30 2013-08-06 Valeritas, Inc. Injection systems
US20060009737A1 (en) * 2004-07-12 2006-01-12 Whiting James S Methods and devices for transseptal access
US7678081B2 (en) * 2004-07-12 2010-03-16 Pacesetter, Inc. Methods and devices for transseptal access
US20130006216A1 (en) * 2010-02-01 2013-01-03 Margaret Taylor Low dose prefilled drug delivery device and method
US9849247B2 (en) * 2010-02-01 2017-12-26 Becton, Dickinson And Company Low dose prefilled drug delivery device and method
US10898648B2 (en) 2010-02-01 2021-01-26 Becton, Dickinson And Company Low dose prefilled drug delivery device and method
US11738150B2 (en) 2010-02-01 2023-08-29 Becton, Dickinson And Company Low dose prefilled drug delivery device and method

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