US3659615A - Encapsulated non-permeable piezoelectric powered pacesetter - Google Patents
Encapsulated non-permeable piezoelectric powered pacesetter Download PDFInfo
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- US3659615A US3659615A US44406A US3659615DA US3659615A US 3659615 A US3659615 A US 3659615A US 44406 A US44406 A US 44406A US 3659615D A US3659615D A US 3659615DA US 3659615 A US3659615 A US 3659615A
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- silicone rubber
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- grade silicone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/378—Electrical supply
- A61N1/3785—Electrical supply generated by biological activity or substance, e.g. body movement
Definitions
- ABSTRACT An encapsulated non-permeable piezoelectric self-powered 'pacesetter for implantation in an in vivo, or living, system in which the pacesetter is sealed and enclosed in an envelope 5 Claims, 3 Drawing Figures Patented May 2, 1972 F IG.
- This invention relates to pacesetters and more particularly to the encapsulated type enclosing a piezoelectric polycrystalline ceramic mechanical to electrical energy converter wherein the enclosure consists of a non-penneable envelope formed of medical grade silicone rubber and natural or synthetic animal, plant or insect wax to provide a compatible ion obstructing or excluding interface between living tissue and the implant.
- the invention embodies two forms, one of which may consist of a material of uniformly integrated medical grade silicone rubber and one or more natural or synthetic waxes of the type disclosed, or another form consisting of a moulded wax providing a highly non-permeable coating to prevent transfer of relatively highly reactive electrolytes or other conductive moisture from entering the areas in which the piezoelectric unit and its associated electrical components are enclosed.
- the outer cover or envelope of medical grade silicone rubber must be compatible with living tissue, while the inner envelope provides a non-permeable coating for the implantable electrical devices associated with the piezoelectrical generator.
- THE DRAWING .closing envelope is formed of an inner body of moulded wax and an outer covering layer of medical grade silicone rubber.
- the figures illustrate forms of the invention which include an encapsulation constructed of materials compatible with living tissue with which they come into contact by implantation in a living system. While the invention is especially useful as a heart pacesetter for implantation in the chest cavity or ad jacent to the heart left ventricle, it is equally useful in other muscular areas of the living system by implantation to stimulate and regulate muscular activity as, for instance, pacing the bladder, blood pressure control centers of the circulatory system, gastro-intestinal tract, the pancreas and other electrically controlled organs of the living system.
- FIGS. 1 and 2 illustrating a simplified and preferred form of the invention.
- the encapsulation is indicated generally at 10 and is formed of a mass composed of substantially uniformly and intimately in tegrated medical grade silicone rubber and one or more natural waxes of the type herein disclosed, imparting a material having high non-permeable qualities to prevent transfer of highly reactive electrolytes or other conductive moisture from entering the areas in which the piezoelectric generator unit and its associated electrical components are enclosed, yet possessing flexibility sufficient to react to muscular movement in the area of its implantation, in a living system.
- Such material is found to be compatible with living tissue with which it comes into contact.
- a transducer comprising elements 12 extend longitudinally along and within the encapsulation l and have imput electrical connection with a conventional piezoelectric generator unit 16 through electrodes of platinum or other suitable tissuecompatible conductors 18 and 20. Electrodes l8 and 20', respectively, are electrically connected with the output side of the unit 16 for purposes of delivering electrical impulses to the specific part of the body or living system in which the electrodes are implanted.
- the piezoelectric generator which is of very high impedance have a relatively slight ability to flex or bend in use to actively generate electrical energy. This is ensured by its encapsulation in a moulded or formed envelope 14 as disclosed herein.
- the encapsulation 14 is preferably formed of either plant, insect or animal wax as distinguished from synthetic wax materials, to provide a highly non-permeable housing for the piezoelectric unit 16 and the transducer element 12 to prevent transfer of highly reactive electrolytes or other conductive moisture from entering the interior of the encapsulation 10.
- piezoelectric bimorphs 12 have internal impedances of approximately 20 megohms and are adequate, for instance, for implantation in beeswax.
- Spermaciti a mammal wax, also provides suitable non-permeable qualities and such waxes are compatible with living tissue. 1 have found that a thickness of non-permeable wax of the group referred to, when applied in a thickness of from 0.15 to 0.50 inch, is quite satisfactory.
- FIG. 3 is illustrated an embodiment 10a which in many respects is similar to that described above in connection with the description of FIGS. 1 and 2, but differs in that an outer envelope of medical grade silicone rubber 22 completely encloses the inner core or encapsulation surrounding the piezoelectric unit and transducer elements 12a and provides a compatible, non-toxic interface between the implant and the living tissue in contact therewith.
- an outer envelope of medical grade silicone rubber 22 completely encloses the inner core or encapsulation surrounding the piezoelectric unit and transducer elements 12a and provides a compatible, non-toxic interface between the implant and the living tissue in contact therewith.
- the thickness of the envelope 22 may vary from 0.30 to 0.10 inch, depending upon the location of the implant or the mechanical requirements.
- the outer cover 22 also serves as a protective layer over the inner wax encapsulation 14a against abrasion that otherwise could occur in the presence of moving muscle or tissue.
- An encapsulated pacesetter implantable in a living system and responsive to movement of an organic muscle to which it is applied to stimulate and pace the natural movement of the muscle, said pacesetter comprising a piezoelectric unit, a transducer, input electrodes electrically connecting said transducer with said generator unit, generator output electrodes for implantation in the muscle tissue, an encapsulating envelope completely enclosing said pacesetter, said envelope formed of a living tissue compatible material consisting of medical grade silicone rubber and a natural wax substantially uniformly and intimately integrated together as a material possessing flexibility sufficient to respond to movement of the muscle tissue in which it is implanted.
- said envelope comprises a natural wax inner enclosure for the generator and the transducer and a medical grade silicone rubber, outer, living tissue compatible envelope.
- the material forming the capsule consists of a natural wax and medical grade silicone rubber intimately and uniformly dispersed throughout the total mass to form an envelope.
- An encapsulated pacesetter comprising an elongate capsule enclosing a piezoelectric generator unit at one end of the capsule, a transducer unit enclosed in the capsule and extending in a direction from said capsule end enclosing said generator to provide a flat flexing portion responsive to movement of organic muscle tissue in which the device is implanted in close proximity thereto, input electrodes within the capsule electrically connecting said transducer with said generator unit and generator output electrodes for implantation in the muscle tissue, said capsule comprising a mass consisting of medical grade silicone rubber and a natural wax.
Abstract
An encapsulated non-permeable piezoelectric self-powered pacesetter for implantation in an in vivo, or living, system in which the pacesetter is sealed and enclosed in an envelope formed of medical grade silicone rubber and preferably natural or synthetic animal, plant or insect wax, in which a piezoelectric poly-crystalline ceramic is completely embedded, enclosed or housed to function as a mechanical to electrical energy converter, when implanted near moving muscle in a living system, and without connection with a separate source of electrical energy either within or without the living system.
Description
United States Patent Enger [54] ENCAPSULATED NON-PERMEABLE PIEZOELECTRIC POWERED PACESETTER [72] inventor: Carl C. Enger, 12700 Lake Avenue, Lakewood, Ohio 44107 [22] Filed: June 8, 1970 [2 1] Appl. No.: 44,406
52 us. 01 ..l28/419 P, 128/419 B 51 1m. (:1. ..A61n 1/36 58 Field ofSearch ..12s/419 P, 419 B, 421,422,
[56] References Cited UNITED STATES PATENTS 3,486,506 12/1969 Auphan ..128/4l9 P PIEZOELECTRIC 20 UNIT 1451 May 2,1972
3,456,!34 7/1969 K0 ..l28/4l9P Primary Examiner-William E. Kamm Attorney-Arthur H. Van Horn [57] ABSTRACT An encapsulated non-permeable piezoelectric self-powered 'pacesetter for implantation in an in vivo, or living, system in which the pacesetter is sealed and enclosed in an envelope 5 Claims, 3 Drawing Figures Patented May 2, 1972 F IG.|
:l8' I PIEZOELECTRIC P20 l4 UNIT FIG.2
INVENTOR. CARL C. EN G E R @MMK ATTORNEY.
ENCAPSULATED NON-PERMEABLE PIEZOELECTRIC POWERED PACESETTER THE INVENTION This invention relates to pacesetters and more particularly to the encapsulated type enclosing a piezoelectric polycrystalline ceramic mechanical to electrical energy converter wherein the enclosure consists of a non-penneable envelope formed of medical grade silicone rubber and natural or synthetic animal, plant or insect wax to provide a compatible ion obstructing or excluding interface between living tissue and the implant.
The invention embodies two forms, one of which may consist of a material of uniformly integrated medical grade silicone rubber and one or more natural or synthetic waxes of the type disclosed, or another form consisting of a moulded wax providing a highly non-permeable coating to prevent transfer of relatively highly reactive electrolytes or other conductive moisture from entering the areas in which the piezoelectric unit and its associated electrical components are enclosed. The outer cover or envelope of medical grade silicone rubber must be compatible with living tissue, while the inner envelope provides a non-permeable coating for the implantable electrical devices associated with the piezoelectrical generator.
THE DRAWING .closing envelope is formed of an inner body of moulded wax and an outer covering layer of medical grade silicone rubber.
DESCRIPTION The figures illustrate forms of the invention which include an encapsulation constructed of materials compatible with living tissue with which they come into contact by implantation in a living system. While the invention is especially useful as a heart pacesetter for implantation in the chest cavity or ad jacent to the heart left ventricle, it is equally useful in other muscular areas of the living system by implantation to stimulate and regulate muscular activity as, for instance, pacing the bladder, blood pressure control centers of the circulatory system, gastro-intestinal tract, the pancreas and other electrically controlled organs of the living system.
Due to its miniature size and compactness, relatively light weight, non-permeability to body fluids and its ability to obstruct or exclude ion passage therethrough, it is readily adaptable to these many uses.
In the drawing, first referring to FIGS. 1 and 2, illustrating a simplified and preferred form of the invention. In this embodiment, which is shown somewhat enlarged for clearness, the encapsulation is indicated generally at 10 and is formed of a mass composed of substantially uniformly and intimately in tegrated medical grade silicone rubber and one or more natural waxes of the type herein disclosed, imparting a material having high non-permeable qualities to prevent transfer of highly reactive electrolytes or other conductive moisture from entering the areas in which the piezoelectric generator unit and its associated electrical components are enclosed, yet possessing flexibility sufficient to react to muscular movement in the area of its implantation, in a living system. Such material is found to be compatible with living tissue with which it comes into contact.
A transducer comprising elements 12 extend longitudinally along and within the encapsulation l and have imput electrical connection with a conventional piezoelectric generator unit 16 through electrodes of platinum or other suitable tissuecompatible conductors 18 and 20. Electrodes l8 and 20', respectively, are electrically connected with the output side of the unit 16 for purposes of delivering electrical impulses to the specific part of the body or living system in which the electrodes are implanted.
It is essential that the piezoelectric generator which is of very high impedance have a relatively slight ability to flex or bend in use to actively generate electrical energy. This is ensured by its encapsulation in a moulded or formed envelope 14 as disclosed herein.
The encapsulation 14 is preferably formed of either plant, insect or animal wax as distinguished from synthetic wax materials, to provide a highly non-permeable housing for the piezoelectric unit 16 and the transducer element 12 to prevent transfer of highly reactive electrolytes or other conductive moisture from entering the interior of the encapsulation 10.
Electrical generators such as piezoelectric bimorphs 12 have internal impedances of approximately 20 megohms and are adequate, for instance, for implantation in beeswax. Spermaciti, a mammal wax, also provides suitable non-permeable qualities and such waxes are compatible with living tissue. 1 have found that a thickness of non-permeable wax of the group referred to, when applied in a thickness of from 0.15 to 0.50 inch, is quite satisfactory.
l have found that the use of synthetic waxes as encapsulants are permeated by ions under the conditions of use in a living system and they do not maintain sufficient dielectric properties over a long period of implantation.
In FIG. 3 is illustrated an embodiment 10a which in many respects is similar to that described above in connection with the description of FIGS. 1 and 2, but differs in that an outer envelope of medical grade silicone rubber 22 completely encloses the inner core or encapsulation surrounding the piezoelectric unit and transducer elements 12a and provides a compatible, non-toxic interface between the implant and the living tissue in contact therewith.
The thickness of the envelope 22 may vary from 0.30 to 0.10 inch, depending upon the location of the implant or the mechanical requirements. The outer cover 22 also serves as a protective layer over the inner wax encapsulation 14a against abrasion that otherwise could occur in the presence of moving muscle or tissue.
I claim: 7
1. An encapsulated pacesetter implantable in a living system and responsive to movement of an organic muscle to which it is applied to stimulate and pace the natural movement of the muscle, said pacesetter comprising a piezoelectric unit, a transducer, input electrodes electrically connecting said transducer with said generator unit, generator output electrodes for implantation in the muscle tissue, an encapsulating envelope completely enclosing said pacesetter, said envelope formed of a living tissue compatible material consisting of medical grade silicone rubber and a natural wax substantially uniformly and intimately integrated together as a material possessing flexibility sufficient to respond to movement of the muscle tissue in which it is implanted.
2. The invention as defined in claim 1 in which said envelope comprises a natural wax inner enclosure for the generator and the transducer and a medical grade silicone rubber, outer, living tissue compatible envelope.
3. The invention defined in claim 1 in which the material forming the capsule consists of a natural wax and medical grade silicone rubber intimately and uniformly dispersed throughout the total mass to form an envelope.
4. An encapsulated pacesetter comprising an elongate capsule enclosing a piezoelectric generator unit at one end of the capsule, a transducer unit enclosed in the capsule and extending in a direction from said capsule end enclosing said generator to provide a flat flexing portion responsive to movement of organic muscle tissue in which the device is implanted in close proximity thereto, input electrodes within the capsule electrically connecting said transducer with said generator unit and generator output electrodes for implantation in the muscle tissue, said capsule comprising a mass consisting of medical grade silicone rubber and a natural wax.
5. The invention of claim 4 in which said encapsulation consists of an inner core of natural wax enclosing said generator,
transducer and input electrodes, and an outer relatively thin interface of medical grade silicone rubber completely enclos ing the core. 5
Claims (4)
- 2. The invention as defined in claim 1 in which said envelope comprises a natural wax inner enclosure for the generator and the transdUcer and a medical grade silicone rubber, outer, living tissue compatible envelope.
- 3. The invention defined in claim 1 in which the material forming the capsule consists of a natural wax and medical grade silicone rubber intimately and uniformly dispersed throughout the total mass to form an envelope.
- 4. An encapsulated pacesetter comprising an elongate capsule enclosing a piezoelectric generator unit at one end of the capsule, a transducer unit enclosed in the capsule and extending in a direction from said capsule end enclosing said generator to provide a flat flexing portion responsive to movement of organic muscle tissue in which the device is implanted in close proximity thereto, input electrodes within the capsule electrically connecting said transducer with said generator unit and generator output electrodes for implantation in the muscle tissue, said capsule comprising a mass consisting of medical grade silicone rubber and a natural wax.
- 5. The invention of claim 4 in which said encapsulation consists of an inner core of natural wax enclosing said generator, transducer and input electrodes, and an outer relatively thin interface of medical grade silicone rubber completely enclosing the core.
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US4440670A | 1970-06-08 | 1970-06-08 |
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Cited By (101)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3941137A (en) * | 1971-02-27 | 1976-03-02 | U.S. Philips Corporation | Ambulatory stimulator |
US4333469A (en) * | 1979-07-20 | 1982-06-08 | Telectronics Pty. Ltd. | Bone growth stimulator |
US4485268A (en) * | 1983-06-13 | 1984-11-27 | Minnesota Mining And Manufacturing | Sealing device for an electrical connector and method therefor |
US4485813A (en) * | 1981-11-19 | 1984-12-04 | Medtronic, Inc. | Implantable dynamic pressure transducer system |
US4545380A (en) * | 1984-04-16 | 1985-10-08 | Cordis Corporation | Method and apparatus for setting and changing parameters or functions of an implanted device |
US4763646A (en) * | 1985-10-04 | 1988-08-16 | Siemens Aktiengesellschaft | Heart pacemaker |
DE3709022A1 (en) * | 1987-03-19 | 1988-09-29 | Alt Eckhard | Frequency-variable pacemaker |
US4793825A (en) * | 1984-09-11 | 1988-12-27 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom And Northern Ireland | Active silicon implant devices |
US4940052A (en) * | 1989-01-25 | 1990-07-10 | Siemens-Pacesetter, Inc. | Microprocessor controlled rate-responsive pacemaker having automatic rate response threshold adjustment |
US4940053A (en) * | 1989-01-25 | 1990-07-10 | Siemens-Pacesetter, Inc. | Energy controlled rate-responsive pacemaker having automatically adjustable control parameters |
US5040534A (en) * | 1989-01-25 | 1991-08-20 | Siemens-Pacesetter, Inc. | Microprocessor controlled rate-responsive pacemaker having automatic rate response threshold adjustment |
US5040535A (en) * | 1989-01-25 | 1991-08-20 | Siemens-Pacesetter, Inc. | Average amplitude controlled rate-responsive pacemaker having automatically adjustable control parameters |
US5332944A (en) * | 1993-10-06 | 1994-07-26 | Cline David J | Environmentally sealed piezoelectric switch assembly |
DE4330680A1 (en) * | 1993-09-10 | 1995-03-16 | Michael Dr Zwicker | Device for electrical stimulation of cells within a living human or animal |
US5431694A (en) * | 1992-08-18 | 1995-07-11 | Snaper; Alvin A. | Bio-operable power source |
US5749909A (en) * | 1996-11-07 | 1998-05-12 | Sulzer Intermedics Inc. | Transcutaneous energy coupling using piezoelectric device |
US5810015A (en) * | 1995-09-01 | 1998-09-22 | Strato/Infusaid, Inc. | Power supply for implantable device |
US5876424A (en) * | 1997-01-23 | 1999-03-02 | Cardiac Pacemakers, Inc. | Ultra-thin hermetic enclosure for implantable medical devices |
US5883459A (en) * | 1997-07-21 | 1999-03-16 | Balboa Instruments Inc. | Electrical switch assembly encapsulated against moisture intrusion |
US5894651A (en) * | 1990-10-29 | 1999-04-20 | Trw Inc. | Method for encapsulating a ceramic device for embedding in composite structures |
US6016020A (en) * | 1997-09-03 | 2000-01-18 | Balboa Instruments, Inc. | Method and apparatus using low voltage level actuator to control operation of electrical appliance |
US6187028B1 (en) | 1998-04-23 | 2001-02-13 | Intermedics Inc. | Capacitors having metallized film with tapered thickness |
US6249423B1 (en) | 1998-04-21 | 2001-06-19 | Cardiac Pacemakers, Inc. | Electrolytic capacitor and multi-anodic attachment |
US6275729B1 (en) | 1998-10-02 | 2001-08-14 | Cardiac Pacemakers, Inc. | Smaller electrolytic capacitors for implantable defibrillators |
US6385490B1 (en) | 1999-12-16 | 2002-05-07 | Cardiac Pacemakers, Inc. | Capacitors with recessed rivets allow smaller implantable defibrillators |
US6421226B1 (en) | 1998-10-02 | 2002-07-16 | Cardiac Pacemakes, Inc. | High-energy capacitors for implantable defibrillators |
US6426864B1 (en) | 2000-06-29 | 2002-07-30 | Cardiac Pacemakers, Inc. | High energy capacitors for implantable defibrillators |
US20020120295A1 (en) * | 2001-02-27 | 2002-08-29 | Olson Renee C. | Battery-less, human-powered electrotherapy device and method of use |
US20030168861A1 (en) * | 2002-02-28 | 2003-09-11 | Estevez Leonardo W. | Generating electric power in response to activity of a biological system |
US6654638B1 (en) * | 2000-04-06 | 2003-11-25 | Cardiac Pacemakers, Inc. | Ultrasonically activated electrodes |
US20040021322A1 (en) * | 2002-07-31 | 2004-02-05 | Arie Ariav | Method and apparatus for body generation of electrical energy |
US20050256549A1 (en) * | 2002-10-09 | 2005-11-17 | Sirius Implantable Systems Ltd. | Micro-generator implant |
US20060034943A1 (en) * | 2003-10-31 | 2006-02-16 | Technology Innovations Llc | Process for treating a biological organism |
US20060061938A1 (en) * | 2004-07-16 | 2006-03-23 | Cardiac Pacemakers, Inc. | Method and apparatus for insulative film for capacitor components |
US20060136004A1 (en) * | 2004-12-21 | 2006-06-22 | Ebr Systems, Inc. | Leadless tissue stimulation systems and methods |
US20060136005A1 (en) * | 2004-12-21 | 2006-06-22 | Ebr Systems, Inc. | Implantable transducer devices |
US20060147371A1 (en) * | 2003-10-31 | 2006-07-06 | Tuszynski Jack A | Water-soluble compound |
US20060175939A1 (en) * | 2003-07-10 | 2006-08-10 | Kazuo Murata | Piezoelectric device and method of producing the same |
US20060217776A1 (en) * | 2005-03-25 | 2006-09-28 | Robert White | Implantable cardiac motion powered piezoelectric energy source |
US20070060961A1 (en) * | 2005-09-12 | 2007-03-15 | Ebr Systems, Inc. | Methods and apparatus for determining cardiac stimulation sites using hemodynamic data |
US20070078490A1 (en) * | 2004-12-21 | 2007-04-05 | Ebr Systems, Inc. | Leadless tissue stimulation systems and methods |
US20070088402A1 (en) * | 2005-10-18 | 2007-04-19 | Melvin David B | Muscle energy converter with smooth continuous tissue interface |
US20080294208A1 (en) * | 2007-05-23 | 2008-11-27 | Ebr Systems, Inc. | Optimizing energy transmission in a leadless tissue stimulation system |
US20090152990A1 (en) * | 2007-12-07 | 2009-06-18 | Veryst Engineering Llc | Apparatus for in vivo energy harvesting |
WO2009120785A2 (en) | 2008-03-25 | 2009-10-01 | Ebr Systems, Inc. | Implantable wireless acoustic stimulators with high energy conversion efficiencies |
WO2010005915A2 (en) * | 2008-07-06 | 2010-01-14 | Synecor Llc | Energy harvesting for implanted medical devices |
US7658196B2 (en) | 2005-02-24 | 2010-02-09 | Ethicon Endo-Surgery, Inc. | System and method for determining implanted device orientation |
US20100140956A1 (en) * | 2008-12-04 | 2010-06-10 | Searete Llc. | Method for generation of power from intraluminal pressure changes |
US20100140957A1 (en) * | 2008-12-04 | 2010-06-10 | Searete Llc | Method for generation of power from intraluminal pressure changes |
US20100140958A1 (en) * | 2008-12-04 | 2010-06-10 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Method for powering devices from intraluminal pressure changes |
WO2010070650A1 (en) | 2008-12-21 | 2010-06-24 | Sirius Implantable Systems Ltd. | High efficiency piezoelectric micro-generator and energy storage system |
US20100160994A1 (en) * | 2007-01-04 | 2010-06-24 | Board Of Regents, The University Of Texas System | Cardiovascular power source for automatic implantable cardioverter defibrillators |
US20100179628A1 (en) * | 2002-08-19 | 2010-07-15 | Arizona Board of Regents, a body corporate acting for and on behalf of Arizona State University | Neurostimulator |
US7765001B2 (en) | 2005-08-31 | 2010-07-27 | Ebr Systems, Inc. | Methods and systems for heart failure prevention and treatments using ultrasound and leadless implantable devices |
US7775966B2 (en) | 2005-02-24 | 2010-08-17 | Ethicon Endo-Surgery, Inc. | Non-invasive pressure measurement in a fluid adjustable restrictive device |
US7775215B2 (en) | 2005-02-24 | 2010-08-17 | Ethicon Endo-Surgery, Inc. | System and method for determining implanted device positioning and obtaining pressure data |
US20100217354A1 (en) * | 2009-02-20 | 2010-08-26 | Biotronik Crm Patent Ag | Active Medical Implant |
US20100234924A1 (en) * | 2008-03-25 | 2010-09-16 | Ebr Systems, Inc. | Operation and estimation of output voltage of wireless stimulators |
US7844342B2 (en) | 2008-02-07 | 2010-11-30 | Ethicon Endo-Surgery, Inc. | Powering implantable restriction systems using light |
US20100317978A1 (en) * | 2009-06-10 | 2010-12-16 | Maile Keith R | Implantable medical device housing modified for piezoelectric energy harvesting |
US20100317977A1 (en) * | 2009-06-10 | 2010-12-16 | Piaget Thomas W | Implantable medical device with internal piezoelectric energy harvesting |
US7927270B2 (en) | 2005-02-24 | 2011-04-19 | Ethicon Endo-Surgery, Inc. | External mechanical pressure sensor for gastric band pressure measurements |
US7953493B2 (en) | 2007-12-27 | 2011-05-31 | Ebr Systems, Inc. | Optimizing size of implantable medical devices by isolating the power source |
US8016744B2 (en) | 2005-02-24 | 2011-09-13 | Ethicon Endo-Surgery, Inc. | External pressure-based gastric band adjustment system and method |
US8016745B2 (en) | 2005-02-24 | 2011-09-13 | Ethicon Endo-Surgery, Inc. | Monitoring of a food intake restriction device |
US20110237967A1 (en) * | 2008-03-25 | 2011-09-29 | Ebr Systems, Inc. | Temporary electrode connection for wireless pacing systems |
US8034065B2 (en) | 2008-02-26 | 2011-10-11 | Ethicon Endo-Surgery, Inc. | Controlling pressure in adjustable restriction devices |
US8057492B2 (en) | 2008-02-12 | 2011-11-15 | Ethicon Endo-Surgery, Inc. | Automatically adjusting band system with MEMS pump |
US8066629B2 (en) | 2005-02-24 | 2011-11-29 | Ethicon Endo-Surgery, Inc. | Apparatus for adjustment and sensing of gastric band pressure |
US8100870B2 (en) | 2007-12-14 | 2012-01-24 | Ethicon Endo-Surgery, Inc. | Adjustable height gastric restriction devices and methods |
US8114345B2 (en) | 2008-02-08 | 2012-02-14 | Ethicon Endo-Surgery, Inc. | System and method of sterilizing an implantable medical device |
WO2012020034A1 (en) | 2010-08-09 | 2012-02-16 | Pi-Harvest Holding Ag | Medical system, piezoelectric kit, related methods and medical procedures |
US8142452B2 (en) | 2007-12-27 | 2012-03-27 | Ethicon Endo-Surgery, Inc. | Controlling pressure in adjustable restriction devices |
US8152710B2 (en) | 2006-04-06 | 2012-04-10 | Ethicon Endo-Surgery, Inc. | Physiological parameter analysis for an implantable restriction device and a data logger |
US8187162B2 (en) | 2008-03-06 | 2012-05-29 | Ethicon Endo-Surgery, Inc. | Reorientation port |
US8187163B2 (en) | 2007-12-10 | 2012-05-29 | Ethicon Endo-Surgery, Inc. | Methods for implanting a gastric restriction device |
US8192350B2 (en) | 2008-01-28 | 2012-06-05 | Ethicon Endo-Surgery, Inc. | Methods and devices for measuring impedance in a gastric restriction system |
US8221439B2 (en) | 2008-02-07 | 2012-07-17 | Ethicon Endo-Surgery, Inc. | Powering implantable restriction systems using kinetic motion |
US8233995B2 (en) | 2008-03-06 | 2012-07-31 | Ethicon Endo-Surgery, Inc. | System and method of aligning an implantable antenna |
US8337389B2 (en) | 2008-01-28 | 2012-12-25 | Ethicon Endo-Surgery, Inc. | Methods and devices for diagnosing performance of a gastric restriction system |
US8377079B2 (en) | 2007-12-27 | 2013-02-19 | Ethicon Endo-Surgery, Inc. | Constant force mechanisms for regulating restriction devices |
US8591395B2 (en) | 2008-01-28 | 2013-11-26 | Ethicon Endo-Surgery, Inc. | Gastric restriction device data handling devices and methods |
US8591532B2 (en) | 2008-02-12 | 2013-11-26 | Ethicon Endo-Sugery, Inc. | Automatically adjusting band system |
US8870742B2 (en) | 2006-04-06 | 2014-10-28 | Ethicon Endo-Surgery, Inc. | GUI for an implantable restriction device and a data logger |
US9180285B2 (en) | 2008-03-25 | 2015-11-10 | Ebr Systems, Inc. | Implantable wireless accoustic stimulators with high energy conversion efficiencies |
US9289612B1 (en) | 2014-12-11 | 2016-03-22 | Medtronic Inc. | Coordination of ventricular pacing in a leadless pacing system |
US9353733B2 (en) | 2008-12-04 | 2016-05-31 | Deep Science, Llc | Device and system for generation of power from intraluminal pressure changes |
US9399140B2 (en) | 2014-07-25 | 2016-07-26 | Medtronic, Inc. | Atrial contraction detection by a ventricular leadless pacing device for atrio-synchronous ventricular pacing |
US9492668B2 (en) | 2014-11-11 | 2016-11-15 | Medtronic, Inc. | Mode switching by a ventricular leadless pacing device |
US9492669B2 (en) | 2014-11-11 | 2016-11-15 | Medtronic, Inc. | Mode switching by a ventricular leadless pacing device |
US9526418B2 (en) | 2008-12-04 | 2016-12-27 | Deep Science, Llc | Device for storage of intraluminally generated power |
US9623234B2 (en) | 2014-11-11 | 2017-04-18 | Medtronic, Inc. | Leadless pacing device implantation |
US9631610B2 (en) | 2008-12-04 | 2017-04-25 | Deep Science, Llc | System for powering devices from intraluminal pressure changes |
US9724519B2 (en) | 2014-11-11 | 2017-08-08 | Medtronic, Inc. | Ventricular leadless pacing device mode switching |
US9731139B2 (en) | 2008-07-16 | 2017-08-15 | Ebr Systems, Inc. | Local lead to improve energy efficiency in implantable wireless acoustic stimulators |
US10390720B2 (en) | 2014-07-17 | 2019-08-27 | Medtronic, Inc. | Leadless pacing system including sensing extension |
US10675476B2 (en) | 2016-12-22 | 2020-06-09 | Cardiac Pacemakers, Inc. | Internal thoracic vein placement of a transmitter electrode for leadless stimulation of the heart |
IT201900006717A1 (en) * | 2019-05-10 | 2020-11-10 | Scuola Superiore Di Studi Univ E Di Perfezionamento Santanna | AN IMPROVED MEDICAL DEVICE FOR HEART ELECTRIC STIMULATION |
US11207527B2 (en) | 2016-07-06 | 2021-12-28 | Cardiac Pacemakers, Inc. | Method and system for determining an atrial contraction timing fiducial in a leadless cardiac pacemaker system |
US11654287B2 (en) | 2019-08-30 | 2023-05-23 | Ebr Systems, Inc. | Pulse delivery device including slew rate detector, and associated systems and methods |
US11771901B2 (en) | 2015-11-17 | 2023-10-03 | Inspire Medical Systems, Inc. | Microstimulation sleep disordered breathing (SDB) therapy device |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3456134A (en) * | 1967-10-05 | 1969-07-15 | Us Health Education & Welfare | Piezoelectric energy converter for electronic implants |
US3486506A (en) * | 1965-10-13 | 1969-12-30 | Philips Corp | Heart-actuated,spring driven cardiac stimulator |
-
1970
- 1970-06-08 US US44406A patent/US3659615A/en not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3486506A (en) * | 1965-10-13 | 1969-12-30 | Philips Corp | Heart-actuated,spring driven cardiac stimulator |
US3456134A (en) * | 1967-10-05 | 1969-07-15 | Us Health Education & Welfare | Piezoelectric energy converter for electronic implants |
Cited By (177)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3941137A (en) * | 1971-02-27 | 1976-03-02 | U.S. Philips Corporation | Ambulatory stimulator |
US4333469A (en) * | 1979-07-20 | 1982-06-08 | Telectronics Pty. Ltd. | Bone growth stimulator |
US4485813A (en) * | 1981-11-19 | 1984-12-04 | Medtronic, Inc. | Implantable dynamic pressure transducer system |
US4485268A (en) * | 1983-06-13 | 1984-11-27 | Minnesota Mining And Manufacturing | Sealing device for an electrical connector and method therefor |
US4545380A (en) * | 1984-04-16 | 1985-10-08 | Cordis Corporation | Method and apparatus for setting and changing parameters or functions of an implanted device |
US4793825A (en) * | 1984-09-11 | 1988-12-27 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom And Northern Ireland | Active silicon implant devices |
US4763646A (en) * | 1985-10-04 | 1988-08-16 | Siemens Aktiengesellschaft | Heart pacemaker |
DE3709022A1 (en) * | 1987-03-19 | 1988-09-29 | Alt Eckhard | Frequency-variable pacemaker |
US5040534A (en) * | 1989-01-25 | 1991-08-20 | Siemens-Pacesetter, Inc. | Microprocessor controlled rate-responsive pacemaker having automatic rate response threshold adjustment |
US4940053A (en) * | 1989-01-25 | 1990-07-10 | Siemens-Pacesetter, Inc. | Energy controlled rate-responsive pacemaker having automatically adjustable control parameters |
US4940052A (en) * | 1989-01-25 | 1990-07-10 | Siemens-Pacesetter, Inc. | Microprocessor controlled rate-responsive pacemaker having automatic rate response threshold adjustment |
US5040535A (en) * | 1989-01-25 | 1991-08-20 | Siemens-Pacesetter, Inc. | Average amplitude controlled rate-responsive pacemaker having automatically adjustable control parameters |
US5894651A (en) * | 1990-10-29 | 1999-04-20 | Trw Inc. | Method for encapsulating a ceramic device for embedding in composite structures |
US5431694A (en) * | 1992-08-18 | 1995-07-11 | Snaper; Alvin A. | Bio-operable power source |
DE4330680A1 (en) * | 1993-09-10 | 1995-03-16 | Michael Dr Zwicker | Device for electrical stimulation of cells within a living human or animal |
US5332944A (en) * | 1993-10-06 | 1994-07-26 | Cline David J | Environmentally sealed piezoelectric switch assembly |
US5810015A (en) * | 1995-09-01 | 1998-09-22 | Strato/Infusaid, Inc. | Power supply for implantable device |
US5749909A (en) * | 1996-11-07 | 1998-05-12 | Sulzer Intermedics Inc. | Transcutaneous energy coupling using piezoelectric device |
US5876424A (en) * | 1997-01-23 | 1999-03-02 | Cardiac Pacemakers, Inc. | Ultra-thin hermetic enclosure for implantable medical devices |
US5883459A (en) * | 1997-07-21 | 1999-03-16 | Balboa Instruments Inc. | Electrical switch assembly encapsulated against moisture intrusion |
US6016020A (en) * | 1997-09-03 | 2000-01-18 | Balboa Instruments, Inc. | Method and apparatus using low voltage level actuator to control operation of electrical appliance |
US6249423B1 (en) | 1998-04-21 | 2001-06-19 | Cardiac Pacemakers, Inc. | Electrolytic capacitor and multi-anodic attachment |
US6881232B2 (en) | 1998-04-21 | 2005-04-19 | Cardiac Pacemakers, Inc. | Electrolytic capacitor and multi-anodic attachment |
US20040105212A1 (en) * | 1998-04-21 | 2004-06-03 | Cardiac Pacemakers, Inc. | Electrolytic capacitor and multi-anodic attachment |
US6597564B2 (en) | 1998-04-21 | 2003-07-22 | Cardiac Pacemakers, Inc. | Electrolytic capacitor and multi-anodic attachment |
US6514276B2 (en) | 1998-04-23 | 2003-02-04 | Intermedics, Inc. | Metallized film capacitor for use in implantable defibrillator |
US6187028B1 (en) | 1998-04-23 | 2001-02-13 | Intermedics Inc. | Capacitors having metallized film with tapered thickness |
US6535374B2 (en) | 1998-10-02 | 2003-03-18 | Cardiac Pacemakers, Inc. | Smaller electrolytic capacitors for implantable defibrillators |
US7558051B2 (en) | 1998-10-02 | 2009-07-07 | Cardiac Pacemakers, Inc. | High-energy capacitors for implantable defibrillators |
US20090269610A1 (en) * | 1998-10-02 | 2009-10-29 | O'phelan Michael J | High-energy capacitors for implantable defibrillators |
US7251123B2 (en) | 1998-10-02 | 2007-07-31 | Cardiac Pacemakers, Inc. | Smaller electrolytic capacitors for implantable defibrillators |
US6556863B1 (en) | 1998-10-02 | 2003-04-29 | Cardiac Pacemakers, Inc. | High-energy capacitors for implantable defibrillators |
US6421226B1 (en) | 1998-10-02 | 2002-07-16 | Cardiac Pacemakes, Inc. | High-energy capacitors for implantable defibrillators |
US20060256505A1 (en) * | 1998-10-02 | 2006-11-16 | Cardiac Pacemakers, Inc. | High-energy capacitors for implantable defibrillators |
US7043300B2 (en) | 1998-10-02 | 2006-05-09 | Cardiac Pacemakers, Inc. | High-energy electrolytic capacitors for implantable defibrillators |
US20030223178A1 (en) * | 1998-10-02 | 2003-12-04 | Cardiac Pacemakers, Inc. | Smaller electrolytic capacitors for implantable defibrillators |
US20050237697A1 (en) * | 1998-10-02 | 2005-10-27 | Cardiac Pacemakers, Inc. | Smaller electrolytic capacitors for implantable defibrillators |
US20040039421A1 (en) * | 1998-10-02 | 2004-02-26 | Cardiac Pacemakers, Inc. | High-energy electrolytic capacitors for implantable defibrillators |
US6839224B2 (en) | 1998-10-02 | 2005-01-04 | Cardiac Pacemakers, Inc. | Smaller electrolytic capacitors for implantable defibrillators |
US6275729B1 (en) | 1998-10-02 | 2001-08-14 | Cardiac Pacemakers, Inc. | Smaller electrolytic capacitors for implantable defibrillators |
US6853538B2 (en) | 1999-12-16 | 2005-02-08 | Cardiac Pacemakers, Inc. | Capacitors with recessed rivets allow smaller implantable defibrillators |
US6385490B1 (en) | 1999-12-16 | 2002-05-07 | Cardiac Pacemakers, Inc. | Capacitors with recessed rivets allow smaller implantable defibrillators |
US6654638B1 (en) * | 2000-04-06 | 2003-11-25 | Cardiac Pacemakers, Inc. | Ultrasonically activated electrodes |
US6426864B1 (en) | 2000-06-29 | 2002-07-30 | Cardiac Pacemakers, Inc. | High energy capacitors for implantable defibrillators |
US20020120295A1 (en) * | 2001-02-27 | 2002-08-29 | Olson Renee C. | Battery-less, human-powered electrotherapy device and method of use |
US6546286B2 (en) * | 2001-02-27 | 2003-04-08 | Koninklijke Philips Electronics N.V. | Battery-less, human-powered electrotherapy device |
US6822343B2 (en) | 2002-02-28 | 2004-11-23 | Texas Instruments Incorporated | Generating electric power in response to activity of a biological system |
US20030168861A1 (en) * | 2002-02-28 | 2003-09-11 | Estevez Leonardo W. | Generating electric power in response to activity of a biological system |
US7081683B2 (en) * | 2002-07-31 | 2006-07-25 | Arie Ariav | Method and apparatus for body generation of electrical energy |
US20040021322A1 (en) * | 2002-07-31 | 2004-02-05 | Arie Ariav | Method and apparatus for body generation of electrical energy |
US8340773B2 (en) * | 2002-08-19 | 2012-12-25 | Arizona Board Of Regents, A Body Corporate, Acting For And On Behalf Of Arizona State University | Neurostimulator |
US8626303B2 (en) | 2002-08-19 | 2014-01-07 | Arizona Board Of Regents, A Body Corporate, Acting For And On Behalf Of Arizona State University | Neurostimulator |
US8369956B2 (en) | 2002-08-19 | 2013-02-05 | Arizona Board Of Regents, A Body Corporate, Acting For And On Behalf Of Arizona State University | Neurostimulator |
US10016612B2 (en) | 2002-08-19 | 2018-07-10 | Arizona Board Of Regents On Behalf Of Arizona State University | Neurostimulator |
US8774928B2 (en) | 2002-08-19 | 2014-07-08 | Arizona Board of Regents on Behalf Arizona State University | Neurostimulator |
US9555258B2 (en) | 2002-08-19 | 2017-01-31 | Arizona Board Of Regents On Behalf Of Arizona State Unveristy | Neurostimulator |
US20100179628A1 (en) * | 2002-08-19 | 2010-07-15 | Arizona Board of Regents, a body corporate acting for and on behalf of Arizona State University | Neurostimulator |
US9457196B2 (en) | 2002-08-19 | 2016-10-04 | Arizona Board Of Regents On Behalf Of Arizona State University | Neurostimulator |
US20110077722A1 (en) * | 2002-08-19 | 2011-03-31 | Arizona Board of Regents, a body corporate acting and on behalf of Arizona State University | Neurostimulator |
US20050256549A1 (en) * | 2002-10-09 | 2005-11-17 | Sirius Implantable Systems Ltd. | Micro-generator implant |
US20060175939A1 (en) * | 2003-07-10 | 2006-08-10 | Kazuo Murata | Piezoelectric device and method of producing the same |
US20060034943A1 (en) * | 2003-10-31 | 2006-02-16 | Technology Innovations Llc | Process for treating a biological organism |
US20060147371A1 (en) * | 2003-10-31 | 2006-07-06 | Tuszynski Jack A | Water-soluble compound |
US9333364B2 (en) | 2004-06-15 | 2016-05-10 | Ebr Systems, Inc. | Methods and systems for heart failure treatments using ultrasound and leadless implantable devices |
US20100286744A1 (en) * | 2004-06-15 | 2010-11-11 | Ebr Systems, Inc. | Methods and systems for heart failure treatments using ultrasound and leadless implantable devices |
US7426104B2 (en) | 2004-07-16 | 2008-09-16 | Cardiac Pacemakers, Inc. | Method and apparatus for insulative film for capacitor components |
US20060061938A1 (en) * | 2004-07-16 | 2006-03-23 | Cardiac Pacemakers, Inc. | Method and apparatus for insulative film for capacitor components |
US7558631B2 (en) | 2004-12-21 | 2009-07-07 | Ebr Systems, Inc. | Leadless tissue stimulation systems and methods |
US7610092B2 (en) | 2004-12-21 | 2009-10-27 | Ebr Systems, Inc. | Leadless tissue stimulation systems and methods |
US7606621B2 (en) | 2004-12-21 | 2009-10-20 | Ebr Systems, Inc. | Implantable transducer devices |
US20090326601A1 (en) * | 2004-12-21 | 2009-12-31 | Ebr Systems, Inc. | Implantable transducer devices |
US9008776B2 (en) | 2004-12-21 | 2015-04-14 | Ebr Systems, Inc. | Leadless tissue stimulation systems and methods |
US8315701B2 (en) | 2004-12-21 | 2012-11-20 | Ebr Systems, Inc. | Leadless tissue stimulation systems and methods |
US20100063562A1 (en) * | 2004-12-21 | 2010-03-11 | Ebr Systems, Inc. | Leadless tissue stimulation systems and methods |
US7996087B2 (en) | 2004-12-21 | 2011-08-09 | Ebr Systems, Inc. | Leadless tissue stimulation systems and methods |
US20060136004A1 (en) * | 2004-12-21 | 2006-06-22 | Ebr Systems, Inc. | Leadless tissue stimulation systems and methods |
US7890173B2 (en) | 2004-12-21 | 2011-02-15 | Ebr Systems, Inc. | Implantable transducer devices |
US7848815B2 (en) | 2004-12-21 | 2010-12-07 | Ebr Systems, Inc. | Implantable transducer devices |
US20070078490A1 (en) * | 2004-12-21 | 2007-04-05 | Ebr Systems, Inc. | Leadless tissue stimulation systems and methods |
US20100228308A1 (en) * | 2004-12-21 | 2010-09-09 | Ebr Systems, Inc. | Leadless tissue stimulation systems and methods |
US20060136005A1 (en) * | 2004-12-21 | 2006-06-22 | Ebr Systems, Inc. | Implantable transducer devices |
US7775215B2 (en) | 2005-02-24 | 2010-08-17 | Ethicon Endo-Surgery, Inc. | System and method for determining implanted device positioning and obtaining pressure data |
US7927270B2 (en) | 2005-02-24 | 2011-04-19 | Ethicon Endo-Surgery, Inc. | External mechanical pressure sensor for gastric band pressure measurements |
US7658196B2 (en) | 2005-02-24 | 2010-02-09 | Ethicon Endo-Surgery, Inc. | System and method for determining implanted device orientation |
US8066629B2 (en) | 2005-02-24 | 2011-11-29 | Ethicon Endo-Surgery, Inc. | Apparatus for adjustment and sensing of gastric band pressure |
US8016745B2 (en) | 2005-02-24 | 2011-09-13 | Ethicon Endo-Surgery, Inc. | Monitoring of a food intake restriction device |
US7775966B2 (en) | 2005-02-24 | 2010-08-17 | Ethicon Endo-Surgery, Inc. | Non-invasive pressure measurement in a fluid adjustable restrictive device |
US8016744B2 (en) | 2005-02-24 | 2011-09-13 | Ethicon Endo-Surgery, Inc. | External pressure-based gastric band adjustment system and method |
US7729768B2 (en) * | 2005-03-25 | 2010-06-01 | Proteus Biomedical, Inc. | Implantable cardiac motion powered piezoelectric energy source |
US20100228312A1 (en) * | 2005-03-25 | 2010-09-09 | Robert White | Implantable Cardiac Motion Powered Piezoelectric Energy Source |
US20060217776A1 (en) * | 2005-03-25 | 2006-09-28 | Robert White | Implantable cardiac motion powered piezoelectric energy source |
US20090000090A1 (en) * | 2005-05-09 | 2009-01-01 | Cardiac Pacemakers, Inc. | Method for insulative film for capacitor components |
US7699899B2 (en) | 2005-05-09 | 2010-04-20 | Cardiac Pacemakers, Inc. | Method for insulative film for capacitor components |
US10207115B2 (en) | 2005-08-31 | 2019-02-19 | Ebr Systems, Inc. | Method and systems for heart failure prevention and treatments using ultrasound and leadless implantable devices |
US7765001B2 (en) | 2005-08-31 | 2010-07-27 | Ebr Systems, Inc. | Methods and systems for heart failure prevention and treatments using ultrasound and leadless implantable devices |
US11376439B2 (en) | 2005-08-31 | 2022-07-05 | Ebr Systems, Inc. | Methods and systems for heart failure prevention and treatments using ultrasound and leadless implantable devices |
US7702392B2 (en) | 2005-09-12 | 2010-04-20 | Ebr Systems, Inc. | Methods and apparatus for determining cardiac stimulation sites using hemodynamic data |
US20070060961A1 (en) * | 2005-09-12 | 2007-03-15 | Ebr Systems, Inc. | Methods and apparatus for determining cardiac stimulation sites using hemodynamic data |
US7715918B2 (en) * | 2005-10-18 | 2010-05-11 | University Of Cincinnati | Muscle energy converter with smooth continuous tissue interface |
US20070088402A1 (en) * | 2005-10-18 | 2007-04-19 | Melvin David B | Muscle energy converter with smooth continuous tissue interface |
US8152710B2 (en) | 2006-04-06 | 2012-04-10 | Ethicon Endo-Surgery, Inc. | Physiological parameter analysis for an implantable restriction device and a data logger |
US8870742B2 (en) | 2006-04-06 | 2014-10-28 | Ethicon Endo-Surgery, Inc. | GUI for an implantable restriction device and a data logger |
WO2008039619A2 (en) | 2006-09-27 | 2008-04-03 | Ebr Systems, Inc. | Temporary leadless pacing systems and methods |
US20100160994A1 (en) * | 2007-01-04 | 2010-06-24 | Board Of Regents, The University Of Texas System | Cardiovascular power source for automatic implantable cardioverter defibrillators |
US20080294208A1 (en) * | 2007-05-23 | 2008-11-27 | Ebr Systems, Inc. | Optimizing energy transmission in a leadless tissue stimulation system |
US10080903B2 (en) | 2007-05-23 | 2018-09-25 | Ebr Systems, Inc. | Optimizing energy transmission in a leadless tissue stimulation system |
US11452879B2 (en) | 2007-05-23 | 2022-09-27 | Ebr Systems, Inc. | Optimizing energy transmission in a leadless tissue stimulation system |
US8718773B2 (en) | 2007-05-23 | 2014-05-06 | Ebr Systems, Inc. | Optimizing energy transmission in a leadless tissue stimulation system |
US10456588B2 (en) | 2007-05-23 | 2019-10-29 | Ebr Systems, Inc. | Optimizing energy transmission in a leadless tissue stimulation system |
US8217523B2 (en) * | 2007-12-07 | 2012-07-10 | Veryst Engineering Llc | Apparatus for in vivo energy harvesting |
US20090152990A1 (en) * | 2007-12-07 | 2009-06-18 | Veryst Engineering Llc | Apparatus for in vivo energy harvesting |
US8187163B2 (en) | 2007-12-10 | 2012-05-29 | Ethicon Endo-Surgery, Inc. | Methods for implanting a gastric restriction device |
US8100870B2 (en) | 2007-12-14 | 2012-01-24 | Ethicon Endo-Surgery, Inc. | Adjustable height gastric restriction devices and methods |
US8377079B2 (en) | 2007-12-27 | 2013-02-19 | Ethicon Endo-Surgery, Inc. | Constant force mechanisms for regulating restriction devices |
US8142452B2 (en) | 2007-12-27 | 2012-03-27 | Ethicon Endo-Surgery, Inc. | Controlling pressure in adjustable restriction devices |
US7953493B2 (en) | 2007-12-27 | 2011-05-31 | Ebr Systems, Inc. | Optimizing size of implantable medical devices by isolating the power source |
US8192350B2 (en) | 2008-01-28 | 2012-06-05 | Ethicon Endo-Surgery, Inc. | Methods and devices for measuring impedance in a gastric restriction system |
US8337389B2 (en) | 2008-01-28 | 2012-12-25 | Ethicon Endo-Surgery, Inc. | Methods and devices for diagnosing performance of a gastric restriction system |
US8591395B2 (en) | 2008-01-28 | 2013-11-26 | Ethicon Endo-Surgery, Inc. | Gastric restriction device data handling devices and methods |
US8221439B2 (en) | 2008-02-07 | 2012-07-17 | Ethicon Endo-Surgery, Inc. | Powering implantable restriction systems using kinetic motion |
US7844342B2 (en) | 2008-02-07 | 2010-11-30 | Ethicon Endo-Surgery, Inc. | Powering implantable restriction systems using light |
US8114345B2 (en) | 2008-02-08 | 2012-02-14 | Ethicon Endo-Surgery, Inc. | System and method of sterilizing an implantable medical device |
US8057492B2 (en) | 2008-02-12 | 2011-11-15 | Ethicon Endo-Surgery, Inc. | Automatically adjusting band system with MEMS pump |
US8591532B2 (en) | 2008-02-12 | 2013-11-26 | Ethicon Endo-Sugery, Inc. | Automatically adjusting band system |
US8034065B2 (en) | 2008-02-26 | 2011-10-11 | Ethicon Endo-Surgery, Inc. | Controlling pressure in adjustable restriction devices |
US8233995B2 (en) | 2008-03-06 | 2012-07-31 | Ethicon Endo-Surgery, Inc. | System and method of aligning an implantable antenna |
US8187162B2 (en) | 2008-03-06 | 2012-05-29 | Ethicon Endo-Surgery, Inc. | Reorientation port |
US9180285B2 (en) | 2008-03-25 | 2015-11-10 | Ebr Systems, Inc. | Implantable wireless accoustic stimulators with high energy conversion efficiencies |
US9283392B2 (en) | 2008-03-25 | 2016-03-15 | Ebr Systems, Inc. | Temporary electrode connection for wireless pacing systems |
US8364276B2 (en) | 2008-03-25 | 2013-01-29 | Ebr Systems, Inc. | Operation and estimation of output voltage of wireless stimulators |
US11752352B2 (en) | 2008-03-25 | 2023-09-12 | Ebr Systems, Inc. | Temporary electrode connection for wireless pacing systems |
EP2452721A1 (en) | 2008-03-25 | 2012-05-16 | EBR Systems, Inc. | Method of manufacturing implantable wireless acoustic stimulators with high energy conversion efficiencies |
US11712572B2 (en) | 2008-03-25 | 2023-08-01 | Ebr Systems, Inc. | Implantable wireless acoustic stimulators with high energy conversion efficiencies |
US10806938B2 (en) | 2008-03-25 | 2020-10-20 | Ebr Systems, Inc. | Implantable wireless accoustic stimulators with high energy conversion efficiencies |
US10688307B2 (en) | 2008-03-25 | 2020-06-23 | Ebr Systems, Inc. | Temporary electrode connection for wireless pacing systems |
WO2009120785A2 (en) | 2008-03-25 | 2009-10-01 | Ebr Systems, Inc. | Implantable wireless acoustic stimulators with high energy conversion efficiencies |
US9907968B2 (en) | 2008-03-25 | 2018-03-06 | Ebr Systems, Inc. | Temporary electrode connection for wireless pacing systems |
US10512785B2 (en) | 2008-03-25 | 2019-12-24 | Ebr Systems, Inc. | Implantable wireless accoustic stimulators with high energy conversion efficiencies |
US20110237967A1 (en) * | 2008-03-25 | 2011-09-29 | Ebr Systems, Inc. | Temporary electrode connection for wireless pacing systems |
US9343654B2 (en) | 2008-03-25 | 2016-05-17 | Ebr Systems, Inc. | Method of manufacturing implantable wireless acoustic stimulators with high energy conversion efficiencies |
US20100234924A1 (en) * | 2008-03-25 | 2010-09-16 | Ebr Systems, Inc. | Operation and estimation of output voltage of wireless stimulators |
US10052493B2 (en) | 2008-03-25 | 2018-08-21 | Ebr Systems, Inc. | Implantable wireless accoustic stimulators with high energy conversion efficiencies |
US9981138B2 (en) | 2008-03-25 | 2018-05-29 | Ebr Systems, Inc. | Operation and estimation of output voltage of wireless stimulators |
WO2010005915A3 (en) * | 2008-07-06 | 2010-04-01 | Synecor Llc | Energy harvesting for implanted medical devices |
WO2010005915A2 (en) * | 2008-07-06 | 2010-01-14 | Synecor Llc | Energy harvesting for implanted medical devices |
US9731139B2 (en) | 2008-07-16 | 2017-08-15 | Ebr Systems, Inc. | Local lead to improve energy efficiency in implantable wireless acoustic stimulators |
US9759202B2 (en) | 2008-12-04 | 2017-09-12 | Deep Science, Llc | Method for generation of power from intraluminal pressure changes |
US9631610B2 (en) | 2008-12-04 | 2017-04-25 | Deep Science, Llc | System for powering devices from intraluminal pressure changes |
US9567983B2 (en) | 2008-12-04 | 2017-02-14 | Deep Science, Llc | Method for generation of power from intraluminal pressure changes |
US9526418B2 (en) | 2008-12-04 | 2016-12-27 | Deep Science, Llc | Device for storage of intraluminally generated power |
US20100140958A1 (en) * | 2008-12-04 | 2010-06-10 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Method for powering devices from intraluminal pressure changes |
US20100140957A1 (en) * | 2008-12-04 | 2010-06-10 | Searete Llc | Method for generation of power from intraluminal pressure changes |
US20100140956A1 (en) * | 2008-12-04 | 2010-06-10 | Searete Llc. | Method for generation of power from intraluminal pressure changes |
US9353733B2 (en) | 2008-12-04 | 2016-05-31 | Deep Science, Llc | Device and system for generation of power from intraluminal pressure changes |
WO2010070650A1 (en) | 2008-12-21 | 2010-06-24 | Sirius Implantable Systems Ltd. | High efficiency piezoelectric micro-generator and energy storage system |
US8401647B2 (en) * | 2009-02-20 | 2013-03-19 | Biotronik Crm Patent Ag | Active medical implant |
US20100217354A1 (en) * | 2009-02-20 | 2010-08-26 | Biotronik Crm Patent Ag | Active Medical Implant |
US8777863B2 (en) * | 2009-06-10 | 2014-07-15 | Cardiac Pacemakers, Inc. | Implantable medical device with internal piezoelectric energy harvesting |
US20100317978A1 (en) * | 2009-06-10 | 2010-12-16 | Maile Keith R | Implantable medical device housing modified for piezoelectric energy harvesting |
US20100317977A1 (en) * | 2009-06-10 | 2010-12-16 | Piaget Thomas W | Implantable medical device with internal piezoelectric energy harvesting |
WO2012020034A1 (en) | 2010-08-09 | 2012-02-16 | Pi-Harvest Holding Ag | Medical system, piezoelectric kit, related methods and medical procedures |
US10390720B2 (en) | 2014-07-17 | 2019-08-27 | Medtronic, Inc. | Leadless pacing system including sensing extension |
US10674928B2 (en) | 2014-07-17 | 2020-06-09 | Medtronic, Inc. | Leadless pacing system including sensing extension |
USRE48197E1 (en) | 2014-07-25 | 2020-09-08 | Medtronic, Inc. | Atrial contraction detection by a ventricular leadless pacing device for atrio-synchronous ventricular pacing |
US9399140B2 (en) | 2014-07-25 | 2016-07-26 | Medtronic, Inc. | Atrial contraction detection by a ventricular leadless pacing device for atrio-synchronous ventricular pacing |
US9492668B2 (en) | 2014-11-11 | 2016-11-15 | Medtronic, Inc. | Mode switching by a ventricular leadless pacing device |
US10279168B2 (en) | 2014-11-11 | 2019-05-07 | Medtronic, Inc. | Leadless pacing device implantation |
US9492669B2 (en) | 2014-11-11 | 2016-11-15 | Medtronic, Inc. | Mode switching by a ventricular leadless pacing device |
US9808628B2 (en) | 2014-11-11 | 2017-11-07 | Medtronic, Inc. | Mode switching by a ventricular leadless pacing device |
US9724519B2 (en) | 2014-11-11 | 2017-08-08 | Medtronic, Inc. | Ventricular leadless pacing device mode switching |
US9623234B2 (en) | 2014-11-11 | 2017-04-18 | Medtronic, Inc. | Leadless pacing device implantation |
US9289612B1 (en) | 2014-12-11 | 2016-03-22 | Medtronic Inc. | Coordination of ventricular pacing in a leadless pacing system |
US11771901B2 (en) | 2015-11-17 | 2023-10-03 | Inspire Medical Systems, Inc. | Microstimulation sleep disordered breathing (SDB) therapy device |
US11207527B2 (en) | 2016-07-06 | 2021-12-28 | Cardiac Pacemakers, Inc. | Method and system for determining an atrial contraction timing fiducial in a leadless cardiac pacemaker system |
US10675476B2 (en) | 2016-12-22 | 2020-06-09 | Cardiac Pacemakers, Inc. | Internal thoracic vein placement of a transmitter electrode for leadless stimulation of the heart |
IT201900006717A1 (en) * | 2019-05-10 | 2020-11-10 | Scuola Superiore Di Studi Univ E Di Perfezionamento Santanna | AN IMPROVED MEDICAL DEVICE FOR HEART ELECTRIC STIMULATION |
US11654287B2 (en) | 2019-08-30 | 2023-05-23 | Ebr Systems, Inc. | Pulse delivery device including slew rate detector, and associated systems and methods |
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