US3620676A - Disposable colorimetric indicator and sampling device for liquids - Google Patents

Disposable colorimetric indicator and sampling device for liquids Download PDF

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Publication number
US3620676A
US3620676A US800887A US3620676DA US3620676A US 3620676 A US3620676 A US 3620676A US 800887 A US800887 A US 800887A US 3620676D A US3620676D A US 3620676DA US 3620676 A US3620676 A US 3620676A
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cavity
coating
indicator
liquid
tubular cavity
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US800887A
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Ward Benjamin Davis
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STERILIZER CONTROL ROYALTIES A
STERILIZER CONTROL ROYALTIES A TRUST
Pymah Corp
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STERILIZER CONTROL ROYALTIES A
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505—Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above

Definitions

  • a disposable colorimetric indicator and sampling device for liquids is formed by embossing a synthetic plastic sheet with a syringelilte cavity and closing the cavity by adhering a plane synthetic plastic sheet over the cavity, the two sheets being either heat sealed or adhesively joined together on the margins around the cavity, the cavity having a tubular portion one end of which opens at the edge of the adhered sheets, and the other end of the cavity being enlarged to form a finger compressible enlargement.
  • a coating of a colorimetric indicator composition, soluble in or reactive with the liquid to be tested, is provided, the liquid being drawn into the tubular cavity by first compressing the enlargement, and releasing the pressure to draw in a liquid sample to react with the colorimetric indicator coating.
  • This invention relates to a simple portable disposable indicator and sampling device by which a sample of an aqueous liquid may be withdrawn from a larger quantity, and tested colorimetrically either qualitatively or semiquantitively for a selected constituent, for examples, for hydrogen ion concentration of a water solution, or for the presence of free chlorine in the water in a swimming pool, or for ascertaining the presence of other chemically detectable ingredients.
  • the device includes not only chemical reagent for detection of the desired ingredient, but also the reaction vessel and the means for filling it with a liquid sample. At least one facet of the device adjacent the tubular cavity is transparent.
  • One object of the invention is to provide inexpensive formed plastic disposable indicators for making semiquantitive analyses of liquids. Another object is to provide means for withdrawing a sample of liquid in a formed syringelike device which also contains a colorimetric reagent. A further object is to provide a syringelike indicator device consisting of a plane plastic backing sheet adhered to an embossed plastic sheet, wherein the embossed figure is a tubular cavity with a closed compressible end portion and an opening at the edge of the device.
  • FIG. 1 is an enlarged plan view of a preferred form of the indicator device
  • FIG. 2 is a cross-sectional view taken on the line 2-2 of FIG. 1;
  • FIG. 3 is a cross-sectional view taken on the line 3-3 of FIG. 1;
  • FIG. 4 is a cross-sectional view taken on the line 4-4 of FIG. 1;
  • FIG. 5 is a cross-sectional view similar to FIG. 4 of an alternative form of my device
  • FIG. 6 is a plan view of a second alternative form of my device.
  • FIG. 7 is a cross-sectional view taken on the line 7-7 of FIG. 6.
  • the indicator device 10 consists of a plane backing sheet 11 of elongated shape such as a trapezoid sr rectangle, and an embossed sheeted front member 12, both of synthetic plastic composition, for example, polyvinyl chloride. At least the from sheet is deformable.
  • the front sheet is preformed in the center portion longitudinally with a half-tubular cavity 13 terminating at the lower edge and a half-bulb cavity 14 connected to said tubular part near the upper edge of the front sheet.
  • the front sheet 12 and the back sheet 11 are heat sealed, or alternatively adhesively joined together in the margins around the cavities so that a tubular portion terminating in a halfor part-bulb are formed, the tubular portion opening in the lower edge of the device at 15.
  • a stripe 16 of a selector indicator composition is imprinted by flexographic printing, on the backing sheet 11 at a position coinciding with the subsequent position of the tube.
  • the indicator devices are manufactured in multiples from large sheets, and subsequently are die-cut into the final individual indicators.
  • the back sheet is printed, flexographically, with properly spaced indicator stripes, and the front sheet is embossed or heat formed with a plurality of connected tube and bulb impressions, and the large sheets are surface joined in aligned superimposition.
  • an opaque sheet 17 may be attached to the transparent backing sheet 11, or the backing sheet may be formed of a white plastic composition to provide a white comparison background for the indicator-produced color in the liquid within the tube.
  • the preferred material for making the indicator device is sheeted polyvinyl chloride plastic, but other sheeted materials having similar properties may be used, for one example polystyrene.
  • the sheet thickness may be varied, but in the range of 6 to 10 mils is satisfactory.
  • the tube opening may be about one thirty-second to one-sixteenth inch by about onequarter inch wide. The dimensions given are illustrative and are not critical.
  • the indicator stripe or coating is preferably printed at the proper location on the backing sheet by flexographic printing using fiexographic-type ink.
  • One such composition for use in detection of hydrogen ion concentration consisted of the following essential ingredients in the approximate proportions, which are not critical:
  • a disposable colorimetric indicator and sampling device for liquids comprising a syringelike body formed with sheets of synthetic plastic, and having a tubular cavity with one end open, at least one face of said tubular cavity being transparent and a colorimetric indicator reagent combined in said cavity.
  • said body comprises plane backing sheet of plastic adhered to the plane margins around a figure embossed in a sheet of plastic, said figure consisting of a tubular cavity having an enlargement closing one end thereof, the open end of said tubular cavity being at one edge of said embossed sheet.

Abstract

A disposable colorimetric indicator and sampling device for liquids is formed by embossing a synthetic plastic sheet with a syringelike cavity and closing the cavity by adhering a plane synthetic plastic sheet over the cavity, the two sheets being either heat sealed or adhesively joined together on the margins around the cavity, the cavity having a tubular portion one end of which opens at the edge of the adhered sheets, and the other end of the cavity being enlarged to form a finger compressible enlargement. A coating of a colorimetric indicator composition, soluble in or reactive with the liquid to be tested, is provided, the liquid being drawn into the tubular cavity by first compressing the enlargement, and releasing the pressure to draw in a liquid sample to react with the colorimetric indicator coating.

Description

United States Patent Inventor Ward Benjamin Davis Glendale, Calif.
Appl. No. 800,887
Filed Feb. 20, 1969 Patented Nov. 16, 1971 Assignee Sterilizer Control Royaltla (a Trust) Los Angeles, Calif.
DISPOSABLE COLORIMETRIC INDICATOR AND SAMPLING DEVICE FOR LIQUIDS 253,259; 206/43,56 A, 17.5; 128/2 R, 231, 132; 116/l14.l9, 114.20
[56] References Cited UNITED STATES PATENTS 2,940,448 6/1960 Furlong, J1. 23/259 UX 3,476,515 11/1969 Johnson et a]. 23/253 X Primary Examiner-Morris O. Wolk Assistant Examiner-R. M. Reese Attorney-Miner L. l-lartmann ABSTRACT: A disposable colorimetric indicator and sampling device for liquids is formed by embossing a synthetic plastic sheet with a syringelilte cavity and closing the cavity by adhering a plane synthetic plastic sheet over the cavity, the two sheets being either heat sealed or adhesively joined together on the margins around the cavity, the cavity having a tubular portion one end of which opens at the edge of the adhered sheets, and the other end of the cavity being enlarged to form a finger compressible enlargement. A coating of a colorimetric indicator composition, soluble in or reactive with the liquid to be tested, is provided, the liquid being drawn into the tubular cavity by first compressing the enlargement, and releasing the pressure to draw in a liquid sample to react with the colorimetric indicator coating.
PATENTEDMJv 15 197i N [/5 N 70 WARD BENJAMIN DA ws DISPOSABLE COLORIMETRIC INDICATOR AND SAMPLING DEVICE FOR LIQUIDS BACKGROUND OF THE INVENTION This invention relates to a simple portable disposable indicator and sampling device by which a sample of an aqueous liquid may be withdrawn from a larger quantity, and tested colorimetrically either qualitatively or semiquantitively for a selected constituent, for examples, for hydrogen ion concentration of a water solution, or for the presence of free chlorine in the water in a swimming pool, or for ascertaining the presence of other chemically detectable ingredients. The device includes not only chemical reagent for detection of the desired ingredient, but also the reaction vessel and the means for filling it with a liquid sample. At least one facet of the device adjacent the tubular cavity is transparent.
One object of the invention is to provide inexpensive formed plastic disposable indicators for making semiquantitive analyses of liquids. Another object is to provide means for withdrawing a sample of liquid in a formed syringelike device which also contains a colorimetric reagent. A further object is to provide a syringelike indicator device consisting of a plane plastic backing sheet adhered to an embossed plastic sheet, wherein the embossed figure is a tubular cavity with a closed compressible end portion and an opening at the edge of the device.
These and other objects are attained by my invention, which will be understood from the following description, reference being made to the accompanying drawings.
BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is an enlarged plan view of a preferred form of the indicator device;
FIG. 2 is a cross-sectional view taken on the line 2-2 of FIG. 1;
FIG. 3 is a cross-sectional view taken on the line 3-3 of FIG. 1;
FIG. 4 is a cross-sectional view taken on the line 4-4 of FIG. 1;
FIG. 5 is a cross-sectional view similar to FIG. 4 of an alternative form of my device;
FIG. 6 is a plan view of a second alternative form of my device; and
FIG. 7 is a cross-sectional view taken on the line 7-7 of FIG. 6.
DESCRIPTION OF PREFERRED EMBODIMENTS Referring to the drawings, particularly FIGS. 1 to 4, the indicator device 10 consists of a plane backing sheet 11 of elongated shape such as a trapezoid sr rectangle, and an embossed sheeted front member 12, both of synthetic plastic composition, for example, polyvinyl chloride. At least the from sheet is deformable. The front sheet is preformed in the center portion longitudinally with a half-tubular cavity 13 terminating at the lower edge and a half-bulb cavity 14 connected to said tubular part near the upper edge of the front sheet. The front sheet 12 and the back sheet 11 are heat sealed, or alternatively adhesively joined together in the margins around the cavities so that a tubular portion terminating in a halfor part-bulb are formed, the tubular portion opening in the lower edge of the device at 15. Prior to the assembly of the parts, a stripe 16 of a selector indicator composition is imprinted by flexographic printing, on the backing sheet 11 at a position coinciding with the subsequent position of the tube.
The indicator devices are manufactured in multiples from large sheets, and subsequently are die-cut into the final individual indicators. The back sheet is printed, flexographically, with properly spaced indicator stripes, and the front sheet is embossed or heat formed with a plurality of connected tube and bulb impressions, and the large sheets are surface joined in aligned superimposition.
As shown in FIG. 5, an opaque sheet 17 may be attached to the transparent backing sheet 11, or the backing sheet may be formed of a white plastic composition to provide a white comparison background for the indicator-produced color in the liquid within the tube.
In the alternative form shown in FIGS. 6 and 7, no enlargement or bulb is provided, and the upper portion of the tubular portion may be compressed and released in the same manner as in the preferred bulb type above described.
The preferred material for making the indicator device is sheeted polyvinyl chloride plastic, but other sheeted materials having similar properties may be used, for one example polystyrene. The sheet thickness may be varied, but in the range of 6 to 10 mils is satisfactory. The tube opening may be about one thirty-second to one-sixteenth inch by about onequarter inch wide. The dimensions given are illustrative and are not critical.
The indicator stripe or coating is preferably printed at the proper location on the backing sheet by flexographic printing using fiexographic-type ink. One such composition for use in detection of hydrogen ion concentration consisted of the following essential ingredients in the approximate proportions, which are not critical:
Methanol 8 parts by weight 2-ethoxyethanol 2 parts by weight Phenol red dye 0.1 to 0.5 parts by weight I claim:
1. A disposable colorimetric indicator and sampling device for liquids, comprising a syringelike body formed with sheets of synthetic plastic, and having a tubular cavity with one end open, at least one face of said tubular cavity being transparent and a colorimetric indicator reagent combined in said cavity.
2. The device defined in claim 1 in which said body comprises plane backing sheet of plastic adhered to the plane margins around a figure embossed in a sheet of plastic, said figure consisting of a tubular cavity having an enlargement closing one end thereof, the open end of said tubular cavity being at one edge of said embossed sheet.
3. The device defined in claim 1 in which the said tubular cavity has a coating over at least part of its inside wall, said coating comprising an indicator reagent soluble in the liquid to be tested.
4. The device defined in claim 2 in which the said tubular cavity has a coating over at least part of its inside wall, said coating comprising an indicator reagent soluble in the liquid to be tested.
5. The device defined in claim 4 in which said partial coating on said tubular cavity wall is a stripe of fiexographic ink comprising a colorimetric pI-I indicator.
6. The device claimed in claim 4 in which said partial coating on said tubular cavity wall is a stripe of flexographic ink comprising a free chlorine indicator.

Claims (5)

  1. 2. The device defined in claim 1 in which said body comprises a plane backing sheet of plastic adhered to the plane margins around a figure embossed in a sheet of plastic, said figure consisting of a tubular cavity having an enlargement closing one end thereof, the open end of said tubular cavity being at one edge of said embossed sheet.
  2. 3. The device defined in claim 1 in which the said tubular cavity has a coating over at least part of its inside wall, said coating comprising an indicator reagent soluble in the liquid to be tested.
  3. 4. The device defined in claim 2 in which the said tubular cavity has a coating over at least part of its inside wall, said coating comprising an indicator reagent soluble in the liquid to be tested.
  4. 5. The device defined in claim 4, in which said partial coating on said tubular cavity wall is a stripe of flexographic ink comprising a colorimetric pH indicator.
  5. 6. The device claimed in claim 4 in which said partial coating on said tubular cavity wall is a stripe of flexographic ink comprising a free chlorine indicator.
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Cited By (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3768974A (en) * 1971-03-22 1973-10-30 Sterilizer Control Royalties Disposable colorimetric indicator device for measuring the concentration of chlorine in water
US3798004A (en) * 1972-04-18 1974-03-19 Ames Yissum Ltd Test device
US3898982A (en) * 1972-11-13 1975-08-12 Jintan Terumo Co Capillary tube for blood examination
US4088448A (en) * 1975-09-29 1978-05-09 Lilja Jan Evert Apparatus for sampling, mixing the sample with a reagent and making particularly optical analyses
WO1979000122A1 (en) * 1977-09-01 1979-03-22 Fospur Ltd Identification of hazardous nature of unknown materials
US4357945A (en) * 1981-06-01 1982-11-09 Janko Albert B Device for testing and rupturing amniotic membrane
US4384485A (en) * 1980-02-11 1983-05-24 The Kendall Company Device for indicating liquid level
US4469110A (en) * 1981-06-25 1984-09-04 Slama Gerard J Device for causing a pinprick to obtain and to test a drop of blood
EP0203930A1 (en) * 1984-11-13 1986-12-10 Cedars Sinai Medical Center Portable blood typing apparatus and method.
US4753249A (en) * 1984-07-19 1988-06-28 Davstar Industries, Inc. Urinometer and patient record combination
US4910406A (en) * 1988-03-23 1990-03-20 E. I. Du Pont De Nemours And Company Method for detecting the presence of contaminants in a reusable plastic food or beverage container
EP0803288A2 (en) * 1996-04-26 1997-10-29 Kyoto Daiichi Kagaku Co., Ltd. Device and method for analyzing a sample
EP0903180A2 (en) * 1997-08-27 1999-03-24 Kyoto Daiichi Kagaku Co., Ltd. Suction generating device and sample analysis apparatus using the same
US6084660A (en) * 1998-07-20 2000-07-04 Lifescan, Inc. Initiation of an analytical measurement in blood
US6125292A (en) * 1997-12-17 2000-09-26 Kyoto Daiichi Kagaku Co., Ltd. Sensor and a set of sensors
DE19933458A1 (en) * 1999-07-15 2001-02-08 Eppendorf Geraetebau Netheler Device for handling liquid samples, system for handling liquid samples and method for producing the device
US6261519B1 (en) 1998-07-20 2001-07-17 Lifescan, Inc. Medical diagnostic device with enough-sample indicator
US20020064480A1 (en) * 1998-07-20 2002-05-30 Shartle Robert Justice Fluidic device for medical diagnostics
US20020098114A1 (en) * 1998-07-20 2002-07-25 Harding Ian A. Microdroplet dispensing for a medical diagnostic device
US20020192833A1 (en) * 2000-07-31 2002-12-19 Victor Pan Method and apparatus for detecting the presence of a fluid on a test strip
US6607701B1 (en) * 1997-10-03 2003-08-19 Hemocue Ab Production of microcuvettes
US6652814B1 (en) 2000-08-11 2003-11-25 Lifescan, Inc. Strip holder for use in a test strip meter
WO2004030821A1 (en) * 2002-09-27 2004-04-15 Klocke Verpackungs-Service Gmbh Device for determining and displaying at least one physical, chemical or biological property of a test liquid
US6777242B1 (en) * 1998-09-09 2004-08-17 Atofina Aqueous solution based on an azo dye, process for its manufacture and use thereof
US6866822B1 (en) 2000-08-11 2005-03-15 Lifescan, Inc. Gimbaled bladder actuator for use with test strips
US20050070021A1 (en) * 2003-09-19 2005-03-31 Quidel Corporation, A Delaware Corporation Iconic colorimetric test device with reduced susceptibility to false positive and false negative readings
US20060000709A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Methods for modulation of flow in a flow pathway
US20060000710A1 (en) * 2004-06-30 2006-01-05 Klaus Peter Weidenhaupt Fluid handling methods
US20060001551A1 (en) * 2004-06-30 2006-01-05 Ulrich Kraft Analyte monitoring system with wireless alarm
US20060002817A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Flow modulation devices
US20060018790A1 (en) * 1996-04-26 2006-01-26 Arkray, Inc. Device and method for analyizing a sample
US7150995B2 (en) 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
US20090137931A1 (en) * 2006-01-05 2009-05-28 Chan Frank A Lancet integrated test element tape dispenser
US7635597B2 (en) 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
US20100116772A1 (en) * 2007-01-31 2010-05-13 Sands Innovations Pty Ltd. dispensing utensil and manufacturing method therefor
US8485360B2 (en) 2011-03-04 2013-07-16 Sands Innovations Pty, Ltd. Fracturable container
US8511500B2 (en) 2010-06-07 2013-08-20 Sands Innovations Pty. Ltd. Dispensing container
US8523016B2 (en) 2008-12-09 2013-09-03 Sands Innovations Pty Ltd. Dispensing container
US8528736B2 (en) 2004-01-02 2013-09-10 Sands Innovations Pty Ltd. Frangible container with hinge cover
US20150087077A1 (en) * 2013-09-26 2015-03-26 Quick Llc Sample collection device for optical analysis
US20150238957A1 (en) * 2011-03-15 2015-08-27 Carclo Technical Plastics Limited Capillary fluid flow control
US20180364176A1 (en) * 2017-06-15 2018-12-20 Tesfa-Michael Tekleab Instantaneous and time-lapse fluid-flow contaminant indicator

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US2940448A (en) * 1957-04-29 1960-06-14 Jr Norman B Furlong Disposable blood-gas analyzer
US3476515A (en) * 1966-04-26 1969-11-04 Du Pont Analytical test pack and process for analysis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2940448A (en) * 1957-04-29 1960-06-14 Jr Norman B Furlong Disposable blood-gas analyzer
US3476515A (en) * 1966-04-26 1969-11-04 Du Pont Analytical test pack and process for analysis

Cited By (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3768974A (en) * 1971-03-22 1973-10-30 Sterilizer Control Royalties Disposable colorimetric indicator device for measuring the concentration of chlorine in water
US3798004A (en) * 1972-04-18 1974-03-19 Ames Yissum Ltd Test device
US3898982A (en) * 1972-11-13 1975-08-12 Jintan Terumo Co Capillary tube for blood examination
US4088448A (en) * 1975-09-29 1978-05-09 Lilja Jan Evert Apparatus for sampling, mixing the sample with a reagent and making particularly optical analyses
WO1979000122A1 (en) * 1977-09-01 1979-03-22 Fospur Ltd Identification of hazardous nature of unknown materials
US4384485A (en) * 1980-02-11 1983-05-24 The Kendall Company Device for indicating liquid level
US4357945A (en) * 1981-06-01 1982-11-09 Janko Albert B Device for testing and rupturing amniotic membrane
US4469110A (en) * 1981-06-25 1984-09-04 Slama Gerard J Device for causing a pinprick to obtain and to test a drop of blood
US4753249A (en) * 1984-07-19 1988-06-28 Davstar Industries, Inc. Urinometer and patient record combination
EP0203930A4 (en) * 1984-11-13 1987-03-26 Cedars Sinai Medical Center Portable blood typing apparatus and method.
EP0203930A1 (en) * 1984-11-13 1986-12-10 Cedars Sinai Medical Center Portable blood typing apparatus and method.
US4910406A (en) * 1988-03-23 1990-03-20 E. I. Du Pont De Nemours And Company Method for detecting the presence of contaminants in a reusable plastic food or beverage container
US7635597B2 (en) 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
US20060018790A1 (en) * 1996-04-26 2006-01-26 Arkray, Inc. Device and method for analyizing a sample
EP0803288A2 (en) * 1996-04-26 1997-10-29 Kyoto Daiichi Kagaku Co., Ltd. Device and method for analyzing a sample
EP0803288A3 (en) * 1996-04-26 1998-09-02 Kyoto Daiichi Kagaku Co., Ltd. Device and method for analyzing a sample
US6991762B1 (en) 1996-04-26 2006-01-31 Arkray, Inc. Device for analyzing a sample
US6001307A (en) * 1996-04-26 1999-12-14 Kyoto Daiichi Kagaku Co., Ltd. Device for analyzing a sample
EP1240945A3 (en) * 1996-04-26 2004-04-21 Arkray, Inc. Device and method for analyzing a sample
US6180062B1 (en) 1996-04-26 2001-01-30 Kyoto Daiichi Kagaku Co., Ltd. Device for analyzing a sample
EP1240945A2 (en) * 1996-04-26 2002-09-18 Kyoto Daiichi Kagaku Co., Ltd. Device and method for analyzing a sample
US6325975B1 (en) 1997-08-27 2001-12-04 Arkray, Inc. Suction generating device and sample analysis apparatus using the same
EP0903180A2 (en) * 1997-08-27 1999-03-24 Kyoto Daiichi Kagaku Co., Ltd. Suction generating device and sample analysis apparatus using the same
EP0903180A3 (en) * 1997-08-27 2000-03-22 Kyoto Daiichi Kagaku Co., Ltd. Suction generating device and sample analysis apparatus using the same
EP1019700B1 (en) * 1997-10-03 2006-12-27 Hemocue AB Production of microcuvettes
US6607701B1 (en) * 1997-10-03 2003-08-19 Hemocue Ab Production of microcuvettes
US6125292A (en) * 1997-12-17 2000-09-26 Kyoto Daiichi Kagaku Co., Ltd. Sensor and a set of sensors
US6521182B1 (en) 1998-07-20 2003-02-18 Lifescan, Inc. Fluidic device for medical diagnostics
US7022286B2 (en) 1998-07-20 2006-04-04 Lifescan, Inc. Fluidic device for medical diagnostics
US20020110922A1 (en) * 1998-07-20 2002-08-15 Shartle Robert Justice Vacuum loaded test strip and method of use
US20040109790A1 (en) * 1998-07-20 2004-06-10 Shartle Robert Justice Vacuum loaded test strip with stop junction and bypass channel
US20020110486A1 (en) * 1998-07-20 2002-08-15 Shartle Robert Justice Analyte test strip with two controls
US20030156984A1 (en) * 1998-07-20 2003-08-21 John Lemke Fluidic device for medical diagnostics
US20030156983A1 (en) * 1998-07-20 2003-08-21 Shartle Robert Justice Fluidic device for medical diagnostics
US20030210287A1 (en) * 1998-07-20 2003-11-13 Harding Ian A. Microdroplet dispensing methods for a medical diagnostic device
US6261519B1 (en) 1998-07-20 2001-07-17 Lifescan, Inc. Medical diagnostic device with enough-sample indicator
US20020098114A1 (en) * 1998-07-20 2002-07-25 Harding Ian A. Microdroplet dispensing for a medical diagnostic device
US6084660A (en) * 1998-07-20 2000-07-04 Lifescan, Inc. Initiation of an analytical measurement in blood
US20020064480A1 (en) * 1998-07-20 2002-05-30 Shartle Robert Justice Fluidic device for medical diagnostics
US6777242B1 (en) * 1998-09-09 2004-08-17 Atofina Aqueous solution based on an azo dye, process for its manufacture and use thereof
US6830934B1 (en) 1999-06-15 2004-12-14 Lifescan, Inc. Microdroplet dispensing for a medical diagnostic device
DE19933458B4 (en) * 1999-07-15 2015-08-20 Eppendorf Ag Equipment and systems for handling liquid samples
DE19933458A1 (en) * 1999-07-15 2001-02-08 Eppendorf Geraetebau Netheler Device for handling liquid samples, system for handling liquid samples and method for producing the device
US7005109B2 (en) 1999-07-15 2006-02-28 Eppendorf Ag System for handling liquid samples
US20020061260A1 (en) * 1999-07-15 2002-05-23 Dieter Husar Device for handling liquid samples and a process for the manufacture of the device, and a system for handling liquid samples
US20020192833A1 (en) * 2000-07-31 2002-12-19 Victor Pan Method and apparatus for detecting the presence of a fluid on a test strip
US20040057878A1 (en) * 2000-08-11 2004-03-25 Allen House Strip holder for use in a test strip meter
US6652814B1 (en) 2000-08-11 2003-11-25 Lifescan, Inc. Strip holder for use in a test strip meter
US6866822B1 (en) 2000-08-11 2005-03-15 Lifescan, Inc. Gimbaled bladder actuator for use with test strips
WO2004030821A1 (en) * 2002-09-27 2004-04-15 Klocke Verpackungs-Service Gmbh Device for determining and displaying at least one physical, chemical or biological property of a test liquid
US20050226767A1 (en) * 2002-09-27 2005-10-13 Hartmut Klocke Device for determing and displaying at least one physical, chemical or biological property of a test liquid
US7255832B2 (en) * 2003-09-19 2007-08-14 Quidel Corporation Iconic colorimetric test device with reduced susceptibility to false positive and false negative readings
US20080032411A1 (en) * 2003-09-19 2008-02-07 Quidel Corporation Iconic Colorimetric Test Device with Reduced Susceptibility To False Positive and False Negative Readings
US20050070021A1 (en) * 2003-09-19 2005-03-31 Quidel Corporation, A Delaware Corporation Iconic colorimetric test device with reduced susceptibility to false positive and false negative readings
US8528736B2 (en) 2004-01-02 2013-09-10 Sands Innovations Pty Ltd. Frangible container with hinge cover
US7150995B2 (en) 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
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