|Publication number||US3620676 A|
|Publication date||16 Nov 1971|
|Filing date||20 Feb 1969|
|Priority date||20 Feb 1969|
|Publication number||US 3620676 A, US 3620676A, US-A-3620676, US3620676 A, US3620676A|
|Inventors||Ward Benjamin Davis|
|Original Assignee||Sterilizer Control Royalties A|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (2), Referenced by (69), Classifications (11), Legal Events (1)|
|External Links: USPTO, USPTO Assignment, Espacenet|
United States Patent Inventor Ward Benjamin Davis Glendale, Calif.
Appl. No. 800,887
Filed Feb. 20, 1969 Patented Nov. 16, 1971 Assignee Sterilizer Control Royaltla (a Trust) Los Angeles, Calif.
DISPOSABLE COLORIMETRIC INDICATOR AND SAMPLING DEVICE FOR LIQUIDS 253,259; 206/43,56 A, 17.5; 128/2 R, 231, 132; 116/l14.l9, 114.20
 References Cited UNITED STATES PATENTS 2,940,448 6/1960 Furlong, J1. 23/259 UX 3,476,515 11/1969 Johnson et a]. 23/253 X Primary Examiner-Morris O. Wolk Assistant Examiner-R. M. Reese Attorney-Miner L. l-lartmann ABSTRACT: A disposable colorimetric indicator and sampling device for liquids is formed by embossing a synthetic plastic sheet with a syringelilte cavity and closing the cavity by adhering a plane synthetic plastic sheet over the cavity, the two sheets being either heat sealed or adhesively joined together on the margins around the cavity, the cavity having a tubular portion one end of which opens at the edge of the adhered sheets, and the other end of the cavity being enlarged to form a finger compressible enlargement. A coating of a colorimetric indicator composition, soluble in or reactive with the liquid to be tested, is provided, the liquid being drawn into the tubular cavity by first compressing the enlargement, and releasing the pressure to draw in a liquid sample to react with the colorimetric indicator coating.
PATENTEDMJv 15 197i N [/5 N 70 WARD BENJAMIN DA ws DISPOSABLE COLORIMETRIC INDICATOR AND SAMPLING DEVICE FOR LIQUIDS BACKGROUND OF THE INVENTION This invention relates to a simple portable disposable indicator and sampling device by which a sample of an aqueous liquid may be withdrawn from a larger quantity, and tested colorimetrically either qualitatively or semiquantitively for a selected constituent, for examples, for hydrogen ion concentration of a water solution, or for the presence of free chlorine in the water in a swimming pool, or for ascertaining the presence of other chemically detectable ingredients. The device includes not only chemical reagent for detection of the desired ingredient, but also the reaction vessel and the means for filling it with a liquid sample. At least one facet of the device adjacent the tubular cavity is transparent.
One object of the invention is to provide inexpensive formed plastic disposable indicators for making semiquantitive analyses of liquids. Another object is to provide means for withdrawing a sample of liquid in a formed syringelike device which also contains a colorimetric reagent. A further object is to provide a syringelike indicator device consisting of a plane plastic backing sheet adhered to an embossed plastic sheet, wherein the embossed figure is a tubular cavity with a closed compressible end portion and an opening at the edge of the device.
These and other objects are attained by my invention, which will be understood from the following description, reference being made to the accompanying drawings.
BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is an enlarged plan view of a preferred form of the indicator device;
FIG. 2 is a cross-sectional view taken on the line 2-2 of FIG. 1;
FIG. 3 is a cross-sectional view taken on the line 3-3 of FIG. 1;
FIG. 4 is a cross-sectional view taken on the line 4-4 of FIG. 1;
FIG. 5 is a cross-sectional view similar to FIG. 4 of an alternative form of my device;
FIG. 6 is a plan view of a second alternative form of my device; and
FIG. 7 is a cross-sectional view taken on the line 7-7 of FIG. 6.
DESCRIPTION OF PREFERRED EMBODIMENTS Referring to the drawings, particularly FIGS. 1 to 4, the indicator device 10 consists of a plane backing sheet 11 of elongated shape such as a trapezoid sr rectangle, and an embossed sheeted front member 12, both of synthetic plastic composition, for example, polyvinyl chloride. At least the from sheet is deformable. The front sheet is preformed in the center portion longitudinally with a half-tubular cavity 13 terminating at the lower edge and a half-bulb cavity 14 connected to said tubular part near the upper edge of the front sheet. The front sheet 12 and the back sheet 11 are heat sealed, or alternatively adhesively joined together in the margins around the cavities so that a tubular portion terminating in a halfor part-bulb are formed, the tubular portion opening in the lower edge of the device at 15. Prior to the assembly of the parts, a stripe 16 of a selector indicator composition is imprinted by flexographic printing, on the backing sheet 11 at a position coinciding with the subsequent position of the tube.
The indicator devices are manufactured in multiples from large sheets, and subsequently are die-cut into the final individual indicators. The back sheet is printed, flexographically, with properly spaced indicator stripes, and the front sheet is embossed or heat formed with a plurality of connected tube and bulb impressions, and the large sheets are surface joined in aligned superimposition.
As shown in FIG. 5, an opaque sheet 17 may be attached to the transparent backing sheet 11, or the backing sheet may be formed of a white plastic composition to provide a white comparison background for the indicator-produced color in the liquid within the tube.
In the alternative form shown in FIGS. 6 and 7, no enlargement or bulb is provided, and the upper portion of the tubular portion may be compressed and released in the same manner as in the preferred bulb type above described.
The preferred material for making the indicator device is sheeted polyvinyl chloride plastic, but other sheeted materials having similar properties may be used, for one example polystyrene. The sheet thickness may be varied, but in the range of 6 to 10 mils is satisfactory. The tube opening may be about one thirty-second to one-sixteenth inch by about onequarter inch wide. The dimensions given are illustrative and are not critical.
The indicator stripe or coating is preferably printed at the proper location on the backing sheet by flexographic printing using fiexographic-type ink. One such composition for use in detection of hydrogen ion concentration consisted of the following essential ingredients in the approximate proportions, which are not critical:
Methanol 8 parts by weight 2-ethoxyethanol 2 parts by weight Phenol red dye 0.1 to 0.5 parts by weight I claim:
1. A disposable colorimetric indicator and sampling device for liquids, comprising a syringelike body formed with sheets of synthetic plastic, and having a tubular cavity with one end open, at least one face of said tubular cavity being transparent and a colorimetric indicator reagent combined in said cavity.
2. The device defined in claim 1 in which said body comprises plane backing sheet of plastic adhered to the plane margins around a figure embossed in a sheet of plastic, said figure consisting of a tubular cavity having an enlargement closing one end thereof, the open end of said tubular cavity being at one edge of said embossed sheet.
3. The device defined in claim 1 in which the said tubular cavity has a coating over at least part of its inside wall, said coating comprising an indicator reagent soluble in the liquid to be tested.
4. The device defined in claim 2 in which the said tubular cavity has a coating over at least part of its inside wall, said coating comprising an indicator reagent soluble in the liquid to be tested.
5. The device defined in claim 4 in which said partial coating on said tubular cavity wall is a stripe of fiexographic ink comprising a colorimetric pI-I indicator.
6. The device claimed in claim 4 in which said partial coating on said tubular cavity wall is a stripe of flexographic ink comprising a free chlorine indicator.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US2940448 *||29 Apr 1957||14 Jun 1960||Jr Norman B Furlong||Disposable blood-gas analyzer|
|US3476515 *||26 Apr 1966||4 Nov 1969||Du Pont||Analytical test pack and process for analysis|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3768974 *||22 Mar 1971||30 Oct 1973||Sterilizer Control Royalties||Disposable colorimetric indicator device for measuring the concentration of chlorine in water|
|US3798004 *||18 Apr 1972||19 Mar 1974||Ames Yissum Ltd||Test device|
|US3898982 *||27 Sep 1973||12 Aug 1975||Jintan Terumo Co||Capillary tube for blood examination|
|US4088448 *||16 Sep 1976||9 May 1978||Lilja Jan Evert||Apparatus for sampling, mixing the sample with a reagent and making particularly optical analyses|
|US4357945 *||1 Jun 1981||9 Nov 1982||Janko Albert B||Device for testing and rupturing amniotic membrane|
|US4384485 *||11 Feb 1980||24 May 1983||The Kendall Company||Device for indicating liquid level|
|US4469110 *||17 Jun 1982||4 Sep 1984||Slama Gerard J||Device for causing a pinprick to obtain and to test a drop of blood|
|US4753249 *||17 Feb 1987||28 Jun 1988||Davstar Industries, Inc.||Urinometer and patient record combination|
|US4910406 *||29 Dec 1988||20 Mar 1990||E. I. Du Pont De Nemours And Company||Method for detecting the presence of contaminants in a reusable plastic food or beverage container|
|US6001307 *||22 Apr 1997||14 Dec 1999||Kyoto Daiichi Kagaku Co., Ltd.||Device for analyzing a sample|
|US6084660 *||16 Jul 1999||4 Jul 2000||Lifescan, Inc.||Initiation of an analytical measurement in blood|
|US6125292 *||7 Dec 1998||26 Sep 2000||Kyoto Daiichi Kagaku Co., Ltd.||Sensor and a set of sensors|
|US6180062||22 Feb 1999||30 Jan 2001||Kyoto Daiichi Kagaku Co., Ltd.||Device for analyzing a sample|
|US6261519||16 Jul 1999||17 Jul 2001||Lifescan, Inc.||Medical diagnostic device with enough-sample indicator|
|US6325975||20 Aug 1998||4 Dec 2001||Arkray, Inc.||Suction generating device and sample analysis apparatus using the same|
|US6521182||15 Jun 1999||18 Feb 2003||Lifescan, Inc.||Fluidic device for medical diagnostics|
|US6607701 *||3 Apr 2000||19 Aug 2003||Hemocue Ab||Production of microcuvettes|
|US6652814||11 Aug 2000||25 Nov 2003||Lifescan, Inc.||Strip holder for use in a test strip meter|
|US6777242 *||8 Sep 1999||17 Aug 2004||Atofina||Aqueous solution based on an azo dye, process for its manufacture and use thereof|
|US6830934||3 Dec 1999||14 Dec 2004||Lifescan, Inc.||Microdroplet dispensing for a medical diagnostic device|
|US6866822||11 Aug 2000||15 Mar 2005||Lifescan, Inc.||Gimbaled bladder actuator for use with test strips|
|US6991762||5 Sep 2000||31 Jan 2006||Arkray, Inc.||Device for analyzing a sample|
|US7005109||14 Jan 2002||28 Feb 2006||Eppendorf Ag||System for handling liquid samples|
|US7022286||26 Dec 2002||4 Apr 2006||Lifescan, Inc.||Fluidic device for medical diagnostics|
|US7150995||16 Jan 2004||19 Dec 2006||Metrika, Inc.||Methods and systems for point of care bodily fluid analysis|
|US7255832 *||17 Sep 2004||14 Aug 2007||Quidel Corporation||Iconic colorimetric test device with reduced susceptibility to false positive and false negative readings|
|US7635597||19 Apr 2004||22 Dec 2009||Bayer Healthcare Llc||Dry reagent particle assay and device having multiple test zones and method therefor|
|US8343074||30 Jun 2004||1 Jan 2013||Lifescan Scotland Limited||Fluid handling devices|
|US8485360||4 Mar 2011||16 Jul 2013||Sands Innovations Pty, Ltd.||Fracturable container|
|US8511500||7 Jun 2010||20 Aug 2013||Sands Innovations Pty. Ltd.||Dispensing container|
|US8523016||9 Dec 2008||3 Sep 2013||Sands Innovations Pty Ltd.||Dispensing container|
|US8528736||8 Oct 2010||10 Sep 2013||Sands Innovations Pty Ltd.||Frangible container with hinge cover|
|US8919594 *||31 Jan 2008||30 Dec 2014||Sands Innovations Pty Ltd||Dispensing container|
|US9352316 *||28 Apr 2015||31 May 2016||Carclo Technical Plastics Limited||Capillary fluid flow control|
|US20020061260 *||14 Jan 2002||23 May 2002||Dieter Husar||Device for handling liquid samples and a process for the manufacture of the device, and a system for handling liquid samples|
|US20020064480 *||17 Jan 2002||30 May 2002||Shartle Robert Justice||Fluidic device for medical diagnostics|
|US20020098114 *||1 Feb 2002||25 Jul 2002||Harding Ian A.||Microdroplet dispensing for a medical diagnostic device|
|US20020110486 *||11 Apr 2002||15 Aug 2002||Shartle Robert Justice||Analyte test strip with two controls|
|US20020110922 *||11 Apr 2002||15 Aug 2002||Shartle Robert Justice||Vacuum loaded test strip and method of use|
|US20020192833 *||26 Aug 2002||19 Dec 2002||Victor Pan||Method and apparatus for detecting the presence of a fluid on a test strip|
|US20030156983 *||26 Dec 2002||21 Aug 2003||Shartle Robert Justice||Fluidic device for medical diagnostics|
|US20030156984 *||26 Dec 2002||21 Aug 2003||John Lemke||Fluidic device for medical diagnostics|
|US20030210287 *||13 Jun 2003||13 Nov 2003||Harding Ian A.||Microdroplet dispensing methods for a medical diagnostic device|
|US20040057878 *||24 Sep 2003||25 Mar 2004||Allen House||Strip holder for use in a test strip meter|
|US20040109790 *||18 Sep 2003||10 Jun 2004||Shartle Robert Justice||Vacuum loaded test strip with stop junction and bypass channel|
|US20050070021 *||17 Sep 2004||31 Mar 2005||Quidel Corporation, A Delaware Corporation||Iconic colorimetric test device with reduced susceptibility to false positive and false negative readings|
|US20050226767 *||23 Sep 2003||13 Oct 2005||Hartmut Klocke||Device for determing and displaying at least one physical, chemical or biological property of a test liquid|
|US20060000709 *||30 Jun 2004||5 Jan 2006||Sebastian Bohm||Methods for modulation of flow in a flow pathway|
|US20060000710 *||30 Jun 2004||5 Jan 2006||Klaus Peter Weidenhaupt||Fluid handling methods|
|US20060001551 *||30 Jun 2004||5 Jan 2006||Ulrich Kraft||Analyte monitoring system with wireless alarm|
|US20060002817 *||30 Jun 2004||5 Jan 2006||Sebastian Bohm||Flow modulation devices|
|US20060018790 *||23 Sep 2005||26 Jan 2006||Arkray, Inc.||Device and method for analyizing a sample|
|US20080032411 *||6 Jul 2007||7 Feb 2008||Quidel Corporation||Iconic Colorimetric Test Device with Reduced Susceptibility To False Positive and False Negative Readings|
|US20090137931 *||26 Jan 2009||28 May 2009||Chan Frank A||Lancet integrated test element tape dispenser|
|US20100116772 *||31 Jan 2008||13 May 2010||Sands Innovations Pty Ltd.||dispensing utensil and manufacturing method therefor|
|US20150238957 *||28 Apr 2015||27 Aug 2015||Carclo Technical Plastics Limited||Capillary fluid flow control|
|DE19933458A1 *||15 Jul 1999||8 Feb 2001||Eppendorf Geraetebau Netheler||Einrichtung zum Handhaben von Flüssigkeitsproben, System zum Handhaben von Flüssigkeitsproben und Verfahren zum Herstellen der Einrichtung|
|DE19933458B4 *||15 Jul 1999||20 Aug 2015||Eppendorf Ag||Einrichtungen und Systeme zum Handhaben von Flüssigkeitsproben|
|EP0203930A1 *||22 Aug 1985||10 Dec 1986||Cedars Sinai Medical Center||Portable blood typing apparatus and method.|
|EP0203930A4 *||22 Aug 1985||26 Mar 1987||Cedars Sinai Medical Center||Portable blood typing apparatus and method.|
|EP0803288A2 *||25 Apr 1997||29 Oct 1997||Kyoto Daiichi Kagaku Co., Ltd.||Device and method for analyzing a sample|
|EP0803288A3 *||25 Apr 1997||2 Sep 1998||Kyoto Daiichi Kagaku Co., Ltd.||Device and method for analyzing a sample|
|EP0903180A2 *||27 Aug 1998||24 Mar 1999||Kyoto Daiichi Kagaku Co., Ltd.||Suction generating device and sample analysis apparatus using the same|
|EP0903180A3 *||27 Aug 1998||22 Mar 2000||Kyoto Daiichi Kagaku Co., Ltd.||Suction generating device and sample analysis apparatus using the same|
|EP1019700B1 *||2 Oct 1998||27 Dec 2006||Hemocue AB||Production of microcuvettes|
|EP1240945A2 *||25 Apr 1997||18 Sep 2002||Kyoto Daiichi Kagaku Co., Ltd.||Device and method for analyzing a sample|
|EP1240945A3 *||25 Apr 1997||21 Apr 2004||Arkray, Inc.||Device and method for analyzing a sample|
|WO1979000122A1 *||31 Aug 1978||22 Mar 1979||Fospur Ltd||Identification of hazardous nature of unknown materials|
|WO2004030821A1 *||23 Sep 2003||15 Apr 2004||Klocke Verpackungs-Service Gmbh||Device for determining and displaying at least one physical, chemical or biological property of a test liquid|
|U.S. Classification||422/405, 600/584, 206/569, 206/305, 206/459.1, 422/944, 116/200, 422/425|
|19 Dec 1988||AS||Assignment|
Owner name: PYMAH CORPORATION
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:DESERET MEDICAL, INC.,;REEL/FRAME:004989/0033
Effective date: 19880601