US3598126A - Vascular canula for medical applications - Google Patents
Vascular canula for medical applications Download PDFInfo
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- US3598126A US3598126A US747712A US3598126DA US3598126A US 3598126 A US3598126 A US 3598126A US 747712 A US747712 A US 747712A US 3598126D A US3598126D A US 3598126DA US 3598126 A US3598126 A US 3598126A
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- Prior art keywords
- canula
- tube
- vascular
- fibers
- wall
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0009—Making of catheters or other medical or surgical tubes
- A61M25/0012—Making of catheters or other medical or surgical tubes with embedded structures, e.g. coils, braids, meshes, strands or radiopaque coils
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/005—Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids
Definitions
- a vascular canula which is intended for insertion into a blood vessel.
- the canula includes a thin-walled tube made of silicone rubber.
- the tubing wall is reinforced with thin fibers to provide a canula which combines softness and flexibility with stability of shape.
- This invention relates to a vascular canula for medical applications.
- the invention relates to a canula for insertion into a blood vessel wherein the canula is of the silicone rubber type.
- Canulae for this purpose are now often manufactured from silicone rubber as this material is tolerated particularly well by the human body. Moreover, canulae made of silicone rubber can be made with very thin walls relative to the diameter of the tubing.
- thin-walled canulae of this type are often so soft that they collapse easily, that is to say they lose their inside round cross section and it may therefore not be advisable to use these thin-walled canulae directly for introduction into the blood vessel.
- vascular canula Another consideration in the use of a vascular canula is that the transition from the inside wall of the blood vessel into the canula should be a continuous as possible in order to avoid the development of vortices in the blood flow which could lead to fibrinous deposits and finally to thrombosis.
- certain forms of silicone rubber canula in present use may sometimes have certain disadvantages by being either too rigid or too soft, or by creating an undesirably abrupt transition between the blood vessel and the interior of the canula. Similar disadvantages may of course also occur in the transition from the canula to the connecting tube to the exterior.
- a canula constructed in accordance with a preferred embodiment of the invention, intended to accomplish at least some of the foregoing objects comprises a thin-walled silicone rubber tube reinforced by fibers extending along the tube.
- the fibers comprise glass fibers embedded into the wall of the silicone rubber canula.
- the fibers are statistically evenly embedded.
- the fibers are embedded into the wall along the main axis and disposed helically therealong.
- the vascular canula may be axially tapered to provide a generally frustoconical leading end of the canula.
- FIG. I is a side view of a canula according to one preferred embodiment of the invention.
- FIG. 2 is a cross-sectional end view of the canula shown in FIG. 1 taken along lines II-II therein;
- FIG. 3 is a side view of a second embodiment of a canula according to the present invention.
- FIG. 4 is a cross-sectional end view of the canula shown in FIG. 3 taken along lines IVIV therein;
- FIG. 5 is a side view of a third embodiment of a canula according to the present invention.
- FIG. 1 of the drawings a canula constructed in accordance with a preferred embodiment of the invention is there shown.
- the canula extends along a longitudinal axis 1 and comprises an axially extending tube 2 defined by a thin wall 3 which is of very much less thickness than the extent of the tube diameter.
- the thickness of the wall 3 may be of the order of 0.2 mm. while the diameter of the tube is of the order of 6- l 0 mm.
- Embedded in the wall 3 are a plurality of glass fibers 4.
- the fibers extend along the tube in a generally uniform helical configuration about the tube. Distribution if the fibers along the tube is made on a statistically even basis to maintain the strength and flexibility characteristics of the canula on an axially uniform basis.
- the fibers 4 are embedded along the main axis in relatively steep helical pitch 7.
- fibers 6 disposed in a less steep helical pitch are provided.
- the canula is provided with a tapering end portion 8 of generally frustoconical form.
- the fibers may be disposed in axially extending relation (FIG. 5) in the third alternative embodiment of the invention to provide an exceptionally elongated tapering point which nevertheless retains its stability of shape to the very tip.
- quartz fibers have thus far been disclosed, other types of fiber may be utilized under certain circumstances.
- embedded fibers formed of extremely fine quartz filaments of a few microns of thickness may be utilized, particularly as quartz fibers gain mechanical strength in an inverse ratio in their thickness so that they are very flexible. Quartz fibers of this type can therefore be bent without tension in exceedingly small radii especially in view of the support afforded by the surrounding silicone rubber.
- Other fibers include metal fibers formed of capillary sliver. If it is desired to provide magnetic or electric current conductivity properties steel or iron fibers may be used. In addition, mixtures of different fiber materials may be employed.
- the embedded fibers provide the canula with a combination of high bending in elasticity and high mechanical strength. If extremely high elasticity of extension is required however, then the fibers are embedded in the tube wall at an increased pitch along the tube (as disclosed in the embodiment of FIG. 3) or else extending axially along the canula (as disclosed in the embodiment of FIG. 5).
- canulae depending on the characteristics desired in the individual case, which canulae are very flexible or else which have great tensile strength. Also, the longitudinal elasticity of the canulae can be influenced through the type of development of fibers.
- FIG. 2 In cross section (FIG. 2) it will be seen that the fibers do not extend into the interior of the tube which thus retains its smooth interior wall characteristics. However, under certain circumstances, it is desirable to cause the embedded fibers to project with a noticeable roughness from the inside surface of the tube. This has the advantage that during use the fibrogerminal cells of the blood settle in the rough spots of the wall surfaces to create a vascular wall within the canula which corresponds to artificial live tissue.
- the fibers invention provides a canula having significant advantages. Even in the case of wall thickness of 0.2 mm. and less and with correspondingly very small diameters, silicone rubber canulae provided with embedded fibers as described, combine the advantage of optimum softness with pronounced stability of shape.
- the tubes and canulae furthermore have the desired smooth surfaces which are peculiar to silicone rubber. Furthermore, these canulae are of wide application because of their high elasticity.
- the canula contains the embedded fibers in a relatively close helical pitch. If, however, increased elasticity of extension is required, then the fibers are embedded in a helical disposition of considerably increased pitch, or extending axially along the canula.
- a vascular canula comprising a silicone rubber tube having a wall thickness of no more than about 0.2 mm., having a nonwoven, helical fiber disposition running in a single axial helical direction, embedded in said tube wall, and running substantially the length of the tube, the fiber material being selected from the group consisting of glass, quartz, silver, steel, and iron, whereby radial expansion of said tube under internal pressure is restricted without severe reduction of the axial extensibility of said tube.
- a vascular canula as defined in claim 1 further including,
- a generally frustoconical, tapered portion of relatively reduced diameter positioned at one extremity of said tube.
Abstract
A vascular canula which is intended for insertion into a blood vessel. The canula includes a thin-walled tube made of silicone rubber. The tubing wall is reinforced with thin fibers to provide a canula which combines softness and flexibility with stability of shape.
Description
United States Patent Inventor Jose! Hoeltadiein Munster, Westphalia, Germany Appl. No. 747,712 Filed July 25, 1968 Patented Aug. 10, U7] Assignee Baxter Laboratories, Inc.
Morton Grove, ll. Priority Apr. 30, 1968 Y H 62 605/30k Gh- VASCULAR CANULA FOR MEDICAL OTHER REFERENCES Dow Corning Bulletin, Vol. 8, No. 1, Jan. 1966 page 2 re lied on 128/Si1icone DIG.
Reynolds et a1. Surgery, Vol. 58, No. 6 Dec. 1965 pp. 938- 940 128-348 Primary Examiner-Dalton L. Truluck Attorneyswalter C. Kehm and Robert G. Pollock ABSTRACT: A vascular canula which is intended for insertion into a blood vessel. The canula includes a thin-walled tube made of silicone rubber. The tubing wall is reinforced with thin fibers to provide a canula which combines softness and flexibility with stability of shape.
This invention relates to a vascular canula for medical applications. In particular the invention relates to a canula for insertion into a blood vessel wherein the canula is of the silicone rubber type.
In medical technique it is often necessary to insert a thin canula or tube into a vessel such as an artery. In doing so it is customary to place a ligature around the blood vessel so that blood cannot escape along the outside of the canula. In order to prevent bulging from developing between the exterior of the canula and the interior of the blood vessel, the ligature is usually placed as close as possible to the end of the canula. The remote end of the canula may be placed connected with a suitable tube to guide the blood externally of the patient for appropriate treatment. A similar arrangement may be made for returning blood to the body.
Canulae for this purpose are now often manufactured from silicone rubber as this material is tolerated particularly well by the human body. Moreover, canulae made of silicone rubber can be made with very thin walls relative to the diameter of the tubing.
However, certain considerations should be borne in mind in the use of silicone rubber canulae. For example, thin-walled canulae of this type are often so soft that they collapse easily, that is to say they lose their inside round cross section and it may therefore not be advisable to use these thin-walled canulae directly for introduction into the blood vessel.
Another consideration in the use of a vascular canula is that the transition from the inside wall of the blood vessel into the canula should be a continuous as possible in order to avoid the development of vortices in the blood flow which could lead to fibrinous deposits and finally to thrombosis.
Additionally, it is important that the inside skin of blood vessel should not be mechanically irritated.
Summarizing, certain forms of silicone rubber canula in present use may sometimes have certain disadvantages by being either too rigid or too soft, or by creating an undesirably abrupt transition between the blood vessel and the interior of the canula. Similar disadvantages may of course also occur in the transition from the canula to the connecting tube to the exterior.
OBJECTS AND SUMMARY OF THE INVENTION It is therefore a general object of the invention to provide a canula which obviates or minimizes problems of the type generally noted above.
It is a particular object of the invention to provide a thin walled canula formed of silicone rubber which combines very great mechanical strength and stability of shape with the customary surface smoothness of silicone rubber.
A canula constructed in accordance with a preferred embodiment of the invention, intended to accomplish at least some of the foregoing objects comprises a thin-walled silicone rubber tube reinforced by fibers extending along the tube.
In the preferred embodiment the fibers comprise glass fibers embedded into the wall of the silicone rubber canula. The fibers are statistically evenly embedded.
In further refinements of the invention, the fibers are embedded into the wall along the main axis and disposed helically therealong. In addition, the vascular canula may be axially tapered to provide a generally frustoconical leading end of the canula.
THE DRAWINGS A canula according to certain preferred embodiments of the invention is illustrated in the accompanying drawings in which;
FIG. I is a side view of a canula according to one preferred embodiment of the invention;
FIG. 2 is a cross-sectional end view of the canula shown in FIG. 1 taken along lines II-II therein;
FIG. 3 is a side view ofa second embodiment ofa canula according to the present invention;
FIG. 4 is a cross-sectional end view of the canula shown in FIG. 3 taken along lines IVIV therein; and
FIG. 5 is a side view of a third embodiment of a canula according to the present invention.
DETAILED DESCRIPTION Referring to FIG. 1 of the drawings, a canula constructed in accordance with a preferred embodiment of the invention is there shown. The canula extends along a longitudinal axis 1 and comprises an axially extending tube 2 defined by a thin wall 3 which is of very much less thickness than the extent of the tube diameter. For example, the thickness of the wall 3 may be of the order of 0.2 mm. while the diameter of the tube is of the order of 6- l 0 mm.
Embedded in the wall 3 are a plurality of glass fibers 4. The fibers extend along the tube in a generally uniform helical configuration about the tube. Distribution if the fibers along the tube is made on a statistically even basis to maintain the strength and flexibility characteristics of the canula on an axially uniform basis. In the preferred embodiment the fibers 4 are embedded along the main axis in relatively steep helical pitch 7.
However, in the second alternative embodiment shown in FIG. 3, fibers 6 disposed in a less steep helical pitch are provided.
As disclosed in FIG. 1 the canula is provided with a tapering end portion 8 of generally frustoconical form.
Additionally, the fibers may be disposed in axially extending relation (FIG. 5) in the third alternative embodiment of the invention to provide an exceptionally elongated tapering point which nevertheless retains its stability of shape to the very tip.
Although glass fibers have thus far been disclosed, other types of fiber may be utilized under certain circumstances. In particular, embedded fibers formed of extremely fine quartz filaments of a few microns of thickness may be utilized, particularly as quartz fibers gain mechanical strength in an inverse ratio in their thickness so that they are very flexible. Quartz fibers of this type can therefore be bent without tension in exceedingly small radii especially in view of the support afforded by the surrounding silicone rubber. Other fibers include metal fibers formed of capillary sliver. If it is desired to provide magnetic or electric current conductivity properties steel or iron fibers may be used. In addition, mixtures of different fiber materials may be employed.
The embedded fibers provide the canula with a combination of high bending in elasticity and high mechanical strength. If extremely high elasticity of extension is required however, then the fibers are embedded in the tube wall at an increased pitch along the tube (as disclosed in the embodiment of FIG. 3) or else extending axially along the canula (as disclosed in the embodiment of FIG. 5).
Thus, one can produce canulae depending on the characteristics desired in the individual case, which canulae are very flexible or else which have great tensile strength. Also, the longitudinal elasticity of the canulae can be influenced through the type of development of fibers.
In cross section (FIG. 2) it will be seen that the fibers do not extend into the interior of the tube which thus retains its smooth interior wall characteristics. However, under certain circumstances, it is desirable to cause the embedded fibers to project with a noticeable roughness from the inside surface of the tube. This has the advantage that during use the fibrogerminal cells of the blood settle in the rough spots of the wall surfaces to create a vascular wall within the canula which corresponds to artificial live tissue.
SUMMARY or ADVANTAGES The fibers invention provides a canula having significant advantages. Even in the case of wall thickness of 0.2 mm. and less and with correspondingly very small diameters, silicone rubber canulae provided with embedded fibers as described, combine the advantage of optimum softness with pronounced stability of shape. The tubes and canulae furthermore have the desired smooth surfaces which are peculiar to silicone rubber. Furthermore, these canulae are of wide application because of their high elasticity.
A particular advantage is afforded by the ease with which the mechanical strength as well as the degree of elasticity may be regulated within wide limits. In some cases where a high bending elasticity and where a high mechanical strength are important, the canula contains the embedded fibers in a relatively close helical pitch. If, however, increased elasticity of extension is required, then the fibers are embedded in a helical disposition of considerably increased pitch, or extending axially along the canula.
it is furthermore an advantage that one can also produce canulae having elongated tapered extreme portions which are pliable to their extremities and yet which retain their rigidity.
Although certain embodiments have been described it will be appreciated by those skilled in the art that numerous additions, deletions, substitutions, modifications, and other changes not specifically disclosed or described may be made which will fall within the purview of the appended claims.
Iclaim:
l. A vascular canula comprising a silicone rubber tube having a wall thickness of no more than about 0.2 mm., having a nonwoven, helical fiber disposition running in a single axial helical direction, embedded in said tube wall, and running substantially the length of the tube, the fiber material being selected from the group consisting of glass, quartz, silver, steel, and iron, whereby radial expansion of said tube under internal pressure is restricted without severe reduction of the axial extensibility of said tube.
2. A vascular canula as defined in claim I wherein, the fiber material is gloss.
3. A- vascular canula as defined in claim 1 wherein, said fibers extend at least partially from said wall into the interior of said tube to make the interior of said tube noticeably rough.
4. A vascular canula as defined in claim 1 further including,
a generally frustoconical, tapered portion of relatively reduced diameter positioned at one extremity of said tube.
5. The canula of claim I in which said fiber material is steel.
6. The canula of claim 1 in which said fiber material is quartz.
Claims (6)
1. A vascular canula comprising a silicone rubber tube having a wall thickness of no more than about 0.2 mm., having a nonwoven, helical fiber disposition running in a single axial helical direction, embedded in said tube wall, and running substantially the length of the tube, the fiber material being selected from the group consisting of glass, quartz, silver, steel, and iron, whereby radial expansion of said tube under internal pressure is restricted without severe reduction of the axial extensibility of said tube.
2. A vascular canula as defined in claim 1 wherein, the fiber material is glass.
3. A vascular canula as defined in claim 1 wherein, said fibers extend at least partially from said wall into the interior of said tube to make the interior of said tube noticeably rough.
4. A vascular canula as defined in claim 1 further including, a generally frustoconical, tapered portion of relatively reduced diameter positioned at one extremity of said tube.
5. The canula of claim 1 in which said fiber material is steel.
6. The canula of claim 1 in which said fiber material is quartz.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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DEH0062605 | 1968-04-30 |
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US3598126A true US3598126A (en) | 1971-08-10 |
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US747712A Expired - Lifetime US3598126A (en) | 1968-04-30 | 1968-07-25 | Vascular canula for medical applications |
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Cited By (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3687129A (en) * | 1970-10-02 | 1972-08-29 | Abcor Inc | Contraceptive device and method of employing same |
US3757768A (en) * | 1972-04-07 | 1973-09-11 | Medical Evaluation Devices And | Manipulable spring guide-catheter and tube for intravenous feeding |
US3905399A (en) * | 1973-01-02 | 1975-09-16 | Uniroyal Ltd | Liquid-conveying hose |
US3921674A (en) * | 1974-03-18 | 1975-11-25 | Dayco Corp | Hose construction and method of making same |
US3924632A (en) * | 1972-12-07 | 1975-12-09 | William A Cook | Fiber glass reinforced catheter |
US4003581A (en) * | 1973-06-06 | 1977-01-18 | Chevron Research Company | Field dressable inflatable packer |
US4106967A (en) * | 1975-11-18 | 1978-08-15 | Dayco Corporation | Hose construction and method of making same |
US4173981A (en) * | 1977-05-23 | 1979-11-13 | University Of Utah | Cannula for arterial and venous bypass cannulation |
JPS5767751U (en) * | 1980-10-09 | 1982-04-23 | ||
US4343788A (en) * | 1979-06-29 | 1982-08-10 | The Procter & Gamble Company | Antimicrobial polymer compositions |
US4354491A (en) * | 1979-03-18 | 1982-10-19 | Marbry Steven L | Fluid transfer device |
US4392848A (en) * | 1979-06-25 | 1983-07-12 | The Procter & Gamble Company | Catheterization |
US4448195A (en) * | 1981-05-08 | 1984-05-15 | Leveen Harry H | Reinforced balloon catheter |
US4479795A (en) * | 1979-06-29 | 1984-10-30 | The Procter & Gamble Company | Antimicrobial polymer compositions |
US4553959A (en) * | 1982-01-27 | 1985-11-19 | The Victoria University Of Manchester | Urethral catheter |
US4571241A (en) * | 1983-12-16 | 1986-02-18 | Christopher T Graham | Urinary catheter with collapsible urethral tube |
US4638803A (en) * | 1982-09-30 | 1987-01-27 | Rand Robert W | Medical apparatus for inducing scar tissue formation in a body |
EP0341049A2 (en) * | 1988-05-06 | 1989-11-08 | Menlo Care Inc. | Multi-layer cannula structure |
US4886506A (en) * | 1986-12-23 | 1989-12-12 | Baxter Travenol Laboratories, Inc. | Soft tip catheter |
US4981478A (en) * | 1988-09-06 | 1991-01-01 | Advanced Cardiovascular Systems | Composite vascular catheter |
US4990138A (en) * | 1989-07-18 | 1991-02-05 | Baxter International Inc. | Catheter apparatus, and compositions useful for producing same |
US5190520A (en) * | 1990-10-10 | 1993-03-02 | Strato Medical Corporation | Reinforced multiple lumen catheter |
US5217440A (en) * | 1989-10-06 | 1993-06-08 | C. R. Bard, Inc. | Multilaminate coiled film catheter construction |
US5222949A (en) * | 1991-07-23 | 1993-06-29 | Intermed, Inc. | Flexible, noncollapsible catheter tube with hard and soft regions |
US5364357A (en) * | 1989-09-25 | 1994-11-15 | Schneider (Usa) Inc. | Small diameter dilatation catheter having wire reinforced coaxial tubular body |
US5573520A (en) * | 1991-09-05 | 1996-11-12 | Mayo Foundation For Medical Education And Research | Flexible tubular device for use in medical applications |
WO1998050098A1 (en) * | 1997-05-08 | 1998-11-12 | Microvena Corporation | Improved multi-durometer catheter |
US5965204A (en) * | 1989-05-04 | 1999-10-12 | Ad Tech Holdings Limited | Deposition of silver layer on nonconducting substrate |
US6053901A (en) * | 1994-01-18 | 2000-04-25 | Vasca, Inc. | Subcutaneously implanted cannula and method for arterial access |
US20030191447A1 (en) * | 1997-01-09 | 2003-10-09 | Medtronic, Inc. | Oval-shaped cardiac cannula |
US6685680B2 (en) * | 1999-04-20 | 2004-02-03 | Dsu Medical Corporation | Tapered intravenous cannula |
US20060051535A1 (en) * | 2004-09-08 | 2006-03-09 | Arney Michael S | Medical devices |
US20070005003A1 (en) * | 2003-12-31 | 2007-01-04 | Patterson Ryan C | Reinforced multi-lumen catheter |
US20070208300A1 (en) * | 2006-03-01 | 2007-09-06 | Applied Medical Resources Corporation | Gas insufflation and suction/irrigation tubing |
JP2019202174A (en) * | 2009-01-12 | 2019-11-28 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | Infusion device with catheter and method of making catheter |
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Cited By (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3687129A (en) * | 1970-10-02 | 1972-08-29 | Abcor Inc | Contraceptive device and method of employing same |
US3757768A (en) * | 1972-04-07 | 1973-09-11 | Medical Evaluation Devices And | Manipulable spring guide-catheter and tube for intravenous feeding |
US3924632A (en) * | 1972-12-07 | 1975-12-09 | William A Cook | Fiber glass reinforced catheter |
US3905399A (en) * | 1973-01-02 | 1975-09-16 | Uniroyal Ltd | Liquid-conveying hose |
US4003581A (en) * | 1973-06-06 | 1977-01-18 | Chevron Research Company | Field dressable inflatable packer |
US3921674A (en) * | 1974-03-18 | 1975-11-25 | Dayco Corp | Hose construction and method of making same |
US4106967A (en) * | 1975-11-18 | 1978-08-15 | Dayco Corporation | Hose construction and method of making same |
US4173981A (en) * | 1977-05-23 | 1979-11-13 | University Of Utah | Cannula for arterial and venous bypass cannulation |
US4354491A (en) * | 1979-03-18 | 1982-10-19 | Marbry Steven L | Fluid transfer device |
US4392848A (en) * | 1979-06-25 | 1983-07-12 | The Procter & Gamble Company | Catheterization |
US4343788A (en) * | 1979-06-29 | 1982-08-10 | The Procter & Gamble Company | Antimicrobial polymer compositions |
US4479795A (en) * | 1979-06-29 | 1984-10-30 | The Procter & Gamble Company | Antimicrobial polymer compositions |
JPS5767751U (en) * | 1980-10-09 | 1982-04-23 | ||
JPS617735Y2 (en) * | 1980-10-09 | 1986-03-10 | ||
US4448195A (en) * | 1981-05-08 | 1984-05-15 | Leveen Harry H | Reinforced balloon catheter |
US4553959A (en) * | 1982-01-27 | 1985-11-19 | The Victoria University Of Manchester | Urethral catheter |
US4638803A (en) * | 1982-09-30 | 1987-01-27 | Rand Robert W | Medical apparatus for inducing scar tissue formation in a body |
US4571241A (en) * | 1983-12-16 | 1986-02-18 | Christopher T Graham | Urinary catheter with collapsible urethral tube |
US4886506A (en) * | 1986-12-23 | 1989-12-12 | Baxter Travenol Laboratories, Inc. | Soft tip catheter |
EP0341049A2 (en) * | 1988-05-06 | 1989-11-08 | Menlo Care Inc. | Multi-layer cannula structure |
US4994047A (en) * | 1988-05-06 | 1991-02-19 | Menlo Care, Inc. | Multi-layer cannula structure |
EP0341049A3 (en) * | 1988-05-06 | 1991-09-18 | Menlo Care Inc. | Multi-layer cannula structure |
US4981478A (en) * | 1988-09-06 | 1991-01-01 | Advanced Cardiovascular Systems | Composite vascular catheter |
US5965204A (en) * | 1989-05-04 | 1999-10-12 | Ad Tech Holdings Limited | Deposition of silver layer on nonconducting substrate |
US4990138A (en) * | 1989-07-18 | 1991-02-05 | Baxter International Inc. | Catheter apparatus, and compositions useful for producing same |
US5364357A (en) * | 1989-09-25 | 1994-11-15 | Schneider (Usa) Inc. | Small diameter dilatation catheter having wire reinforced coaxial tubular body |
US5217440A (en) * | 1989-10-06 | 1993-06-08 | C. R. Bard, Inc. | Multilaminate coiled film catheter construction |
US5190520A (en) * | 1990-10-10 | 1993-03-02 | Strato Medical Corporation | Reinforced multiple lumen catheter |
US5695482A (en) * | 1991-07-23 | 1997-12-09 | Intermed, Inc. | UV treated catheter |
US5222949A (en) * | 1991-07-23 | 1993-06-29 | Intermed, Inc. | Flexible, noncollapsible catheter tube with hard and soft regions |
US5573520A (en) * | 1991-09-05 | 1996-11-12 | Mayo Foundation For Medical Education And Research | Flexible tubular device for use in medical applications |
US6398764B1 (en) | 1994-01-18 | 2002-06-04 | Vasca. Inc. | Subcutaneously implanted cannula and method for arterial access |
US6053901A (en) * | 1994-01-18 | 2000-04-25 | Vasca, Inc. | Subcutaneously implanted cannula and method for arterial access |
US8167867B2 (en) | 1997-01-09 | 2012-05-01 | Medtronic, Inc. | Oval-shaped cardiac cannula |
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