US3595231A - Device for simultaneously injecting a liquid at a plurality of injection points - Google Patents

Device for simultaneously injecting a liquid at a plurality of injection points Download PDF

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US3595231A
US3595231A US799673A US3595231DA US3595231A US 3595231 A US3595231 A US 3595231A US 799673 A US799673 A US 799673A US 3595231D A US3595231D A US 3595231DA US 3595231 A US3595231 A US 3595231A
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injection
liquid
ducts
nipples
secondary flow
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US799673A
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Michel Louis Paul Pistor
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SOC DITE A GUERIN
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SOC DITE A GUERIN
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3295—Multiple needle devices, e.g. a plurality of needles arranged coaxially or in parallel
    • A61M5/3298—Needles arranged in parallel

Definitions

  • the device consists in dividing a stream of the liquid to be injected into elementary streams feeding nipples connectable to injection needles.
  • the device consists of a body, preferably constituted by a flat cylindrical disc, which comprises a main flow nipple connectable to an injection syringe, a plurality of secondary flow nipples and a network of internal ducts for dividing the main stream of the aforesaid liquid.
  • the present invention relates essentially to injection of a liquid at a given area at a plurality of points or locations.
  • the invention is particularly concerned with a device enabling the simultaneous injection of a liquid under the aforesaid conditions.
  • This device enables in particular but not exclusively to carry out the injection of a treating liquid into a given area of a living tissue, in particular a human tissue; a very particular application of such a device, which is not a part of the invention, is the mesotherapy according to which several subcutaneous injections are effected into a given area of the integument by means of short needles, having for example a length of about 3 mm.
  • the device forming the subject matter of the present invention may be used for effecting nonsubcutaneous, subcutaneous, for example intramuscular injections
  • this device is especially designed for or adapted to subcutaneous injections for various purposes: administration of a local anesthetic, administration of anti-infectious'(for example antibiotics) agents, anticellulitic agents, antirheumatic agents, local analgesic agents (for example against costal pains), and so on.
  • the injection device divides'one or several main streams of liquid, fed or supplied from a liquid tank, into a plurality of elementary streams, of preferably like flow rates using hollow needles in corresponding relationship with these elementary streams to effect the injection at the various aforesaid points.
  • pushing or thrusting means such as a piston arranged within said tank, are used for displacing or moving the liquid from the tank to each one of said hollow needles.
  • the device according to the invention for the simultaneous injection of a liquid at a plurality of points of a given area is characterized in that it comprises a distributor consisting of a body, at least one main flow nipple or like nozzle means, fitting or piping member, adapted to be connected to an injection syringe, a plurality of secondary flow nipples or like nozzle means, fitting or piping'members, adapted to be connected to injection needles, and a network, set or'system of ducts disposed within said body for distributing the injection liquid.
  • nipples may or may not be provided with locking means for the syringe; when no locking is provided, the adapting means used is based in particular on the principle of nesting in interfitting relationship by means of cylindrical or tapering or conical surfaces.
  • said distributor is adapted to carry out an injection into a substantially circular area and comprises for this purpose, a body in the shape of a substan tially flat cylindrical disc on one of the sides or faces of which is located said main flow nipple whereas the secondary flow nipples are arranged on the other side or face thereof.
  • the network of aforesaid ducts has a substantially axial symmetry, said main flow nipple being disposed in the middle or at the center of the disc whereas said network consists essentially of radial ducts.
  • said secondary flow nipples are located within the peripheral area of the disc and possibly in the middle or at the center of said disc.
  • said distributor includes a body of substantially elongate shape, whereas said secondary flow nipples exhibit a substantially linear arrangement.
  • the secondary flow nipples may hardly be at a constant distance from the main flow nipple or main flow nipples, there should be provided, according to a further characterizing feature of the invention, when it is desired to achieve equal flow rates at the level of said secondary flow nipples, differing flow passage sections for the liquid delivered or discharged by each secondary flow nipple.
  • the short channels or ducts establishing the communication between each secondary nipple and the main duct connected to the main nipple could be given cross sections increasing with the distance from said main flow nipple.
  • said distributor is given such a construction that access may be had through outer orifices to the network or system of said ducts, said orifices being provided with removable means such as screw-threaded plugs or the like, so that it may be possible to clean said distributor by mere immersion into boiling water without having to disassemble or dismantle it any further.
  • FIG. 1 shows an elevational view of a device according to the first embodiment of the invention
  • FIG. 2 is a bottom view of the body of such a device
  • FIG. 3 is a cross-sectional view taken upon the line Ill-III of FIG. I ofthe same device;
  • FIG. 4 is an elevational view of a device according to the second embodiment of the invention.
  • FIG. 5 shows a sectional view taken upon the line V-V of FIG. 4 of this same device.
  • the device of FIGS. 1 to 3 is usable in particular for making subcutaneous injections within a substantially circular area.
  • this device consists essentially of'a distributor 1, formed of a disclike body 2 on which is adapted a main flow nozzle 3 and seven secondary flow nozzles 4,5, 6, 7, 8,9 and 10.
  • the axial channel or duct 3a of the flow nipple 3 communicates with six radial ducts 4a, 5a, 6a, 7a, 8a and 9a, respectively connected through short ducts or channels 4b, 5b, 6b, 7b, 8b and 9b, respectively, to the secondary flow nipples 4 to 9.
  • the outer surface of the flow nipple 3 is substantially cylindrical and is formed with fiat portions 3b and 3b, thereby enabling to adapt thereto an injection syringe of conventional type, for example by receiving the syringe in the flow nipple.
  • a flow nipple may be provided, for example of the Luer-Lock type, to allow the adaptation of a syringe having a fiow nipple of corresponding construction, the fiow nipple having a suitable locking means which achieves a locked connection between the disc 2 and the injection syringe.
  • these needles are for example 3 mm. long as to the useful length, ie beyond the flow nipple.
  • the device of FIGS. 1 to 3 is remarkably interesting in mesotherapy; in addition, it may be noted that, due to its construction, it enables a directional effect of each injection needle more precise or accurate than that obtained with the usual injection needles (greater stability of a conventional injection syringe provided with a single needle).
  • the aforesaid distributor is desirably made of plastic or metallic material, for example from stainless steel; it could also be made from a synthetic material or other suitable material.
  • This distributor in particular when it is made from plastic material, may or not be disposed of after each operation.
  • FIGS. 4 and 5 show a distributor the body of which has the shape of an elongated rectangular parallelepiped 18 provided on one of its sides or faces with a main flow nipple 19 and on the other side or face with seven secondary flow nipples ll, 12, 13, 14, 15, 16 and 17, connected through short transverse channels or ducts 11a to 170, respectively, to a longitudinal duct 20 fed by an axial channel or duct 19a of the nipple 19;
  • the diameters of the ducts or channels increase on the one hand according to the order of succession 14a, 13a, 12a and 11a and on the other hand according to the order of succession 14a, 15a, 16a and 17a. thereby enabling upon taking into account the dissymmetry of feed or supply of injection liquid, nevertheless to achieve substantially equal flow rates at the level of the secondary flow nipples 11 to 17.
  • a device for simultaneous injection of a liquid at a plurality of points of a given area wherein the improvement consists in that it comprises a distributor consisting of a body, at least one main flow nipple connectable to an injection syringe, a plurality of secondary flow nipples connectable to injection needles and a network of ducts provided within said body for distributing said injection liquid, said distributor body having the shape ofa substantially flat cylindrical disc on one side of which is located said main flow nipple whereas said secondary flow nipples are located on the other side thereof, said network consisting of substantially radial ducts, said radial ducts communicating with said secondary flow nipples through short substantially axial passageways, whereas said ducts extend to the periphery of said disc where they are adapted to be opened so as to enable their cleaning, removable closure means being provided at the outer ends of said radial ducts.

Abstract

The device consists in dividing a stream of the liquid to be injected into elementary streams feeding nipples connectable to injection needles. The device consists of a body, preferably constituted by a flat cylindrical disc, which comprises a main flow nipple connectable to an injection syringe, a plurality of secondary flow nipples and a network of internal ducts for dividing the main stream of the aforesaid liquid.

Description

United States Patent Inventor Appl. No.
Filed Patented Assignee Priority Michel Louis Paul Pistor Paris, France Feb. 17, 1969 July 27, 1971 Societe dite: A Guerin Paris, France a part interest Feb. 20, 1968 France 140,593
DEVICE FOR SIMULTANEOUSLY INJECTING A LIQUID AT A PLURALIT Y OF INJECTION POINTS 1 Claim, 5 Drawing Figs.
u.s. c| 128/215, 7 128/221,128/253 Int. Cl. A6lm 5/00 Field olSearch 128/218,
Primary Examiner-Joseph S. Reich Attorney-Steinberg and Blake ABSTRACT: The device consists in dividing a stream of the liquid to be injected into elementary streams feeding nipples connectable to injection needles. The device consists of a body, preferably constituted by a flat cylindrical disc, which comprises a main flow nipple connectable to an injection syringe, a plurality of secondary flow nipples and a network of internal ducts for dividing the main stream of the aforesaid liquid.
DEVICE FOR SIMULTANEOUSLY INJECTING A LIQUID AT A PLURALITY OF INJECTION POINTS The present invention relates essentially to injection of a liquid at a given area at a plurality of points or locations.
The invention is particularly concerned with a device enabling the simultaneous injection of a liquid under the aforesaid conditions.
This device enables in particular but not exclusively to carry out the injection of a treating liquid into a given area of a living tissue, in particular a human tissue; a very particular application of such a device, which is not a part of the invention, is the mesotherapy according to which several subcutaneous injections are effected into a given area of the integument by means of short needles, having for example a length of about 3 mm.
Although the device forming the subject matter of the present invention may be used for effecting nonsubcutaneous, subcutaneous, for example intramuscular injections, this device is especially designed for or adapted to subcutaneous injections for various purposes: administration of a local anesthetic, administration of anti-infectious'(for example antibiotics) agents, anticellulitic agents, antirheumatic agents, local analgesic agents (for example against costal pains), and so on.
The injection device according to the invention divides'one or several main streams of liquid, fed or supplied from a liquid tank, into a plurality of elementary streams, of preferably like flow rates using hollow needles in corresponding relationship with these elementary streams to effect the injection at the various aforesaid points.
According to a preferred embodiment, pushing or thrusting means, such as a piston arranged within said tank, are used for displacing or moving the liquid from the tank to each one of said hollow needles.
The device according to the invention for the simultaneous injection of a liquid at a plurality of points of a given area is characterized in that it comprises a distributor consisting of a body, at least one main flow nipple or like nozzle means, fitting or piping member, adapted to be connected to an injection syringe, a plurality of secondary flow nipples or like nozzle means, fitting or piping'members, adapted to be connected to injection needles, and a network, set or'system of ducts disposed within said body for distributing the injection liquid.
The aforesaid nipples may or may not be provided with locking means for the syringe; when no locking is provided, the adapting means used is based in particular on the principle of nesting in interfitting relationship by means of cylindrical or tapering or conical surfaces.
According to a first embodiment, said distributor is adapted to carry out an injection into a substantially circular area and comprises for this purpose, a body in the shape of a substan tially flat cylindrical disc on one of the sides or faces of which is located said main flow nipple whereas the secondary flow nipples are arranged on the other side or face thereof.
According to a feature of this embodiment, the network of aforesaid ducts has a substantially axial symmetry, said main flow nipple being disposed in the middle or at the center of the disc whereas said network consists essentially of radial ducts.
According to a further characterizing feature of the invention, said secondary flow nipples are located within the peripheral area of the disc and possibly in the middle or at the center of said disc.
According to a second form of embodiment of the invention, said distributor includes a body of substantially elongate shape, whereas said secondary flow nipples exhibit a substantially linear arrangement.
According to this embodiment, there may be provided one single duct feeding all of the secondary flow nipples or a network or a system of ducts preferably comprising several parallel ducts.
Since in this second form of embodiment, the secondary flow nipples may hardly be at a constant distance from the main flow nipple or main flow nipples, there should be provided, according to a further characterizing feature of the invention, when it is desired to achieve equal flow rates at the level of said secondary flow nipples, differing flow passage sections for the liquid delivered or discharged by each secondary flow nipple. In particular, the short channels or ducts establishing the communication between each secondary nipple and the main duct connected to the main nipple, could be given cross sections increasing with the distance from said main flow nipple.
According to still another characterizing feature of the invention, said distributor is given such a construction that access may be had through outer orifices to the network or system of said ducts, said orifices being provided with removable means such as screw-threaded plugs or the like, so that it may be possible to clean said distributor by mere immersion into boiling water without having to disassemble or dismantle it any further.
Further characteristics and advantages of the invention will appear as the following description proceeds.
In the accompanying drawings, given by way of example only:
FIG. 1 shows an elevational view of a device according to the first embodiment of the invention;
FIG. 2 is a bottom view of the body ofsuch a device;
FIG. 3 is a cross-sectional view taken upon the line Ill-III of FIG. I ofthe same device;
FIG. 4 is an elevational view of a device according to the second embodiment of the invention;
FIG. 5 shows a sectional view taken upon the line V-V of FIG. 4 of this same device.
The device of FIGS. 1 to 3 is usable in particular for making subcutaneous injections within a substantially circular area.
It is seen in FIGS. 1 to 3 that this device consists essentially of'a distributor 1, formed of a disclike body 2 on which is adapted a main flow nozzle 3 and seven secondary flow nozzles 4,5, 6, 7, 8,9 and 10. The axial channel or duct 3a of the flow nipple 3 communicates with six radial ducts 4a, 5a, 6a, 7a, 8a and 9a, respectively connected through short ducts or channels 4b, 5b, 6b, 7b, 8b and 9b, respectively, to the secondary flow nipples 4 to 9.
These radial ducts open on the periphery of the disc 2 through tapped orifices wherein there are screw-threaded small screwplugs of screws 40, 5e, 6e, 7c, and 9c, respectively.
The outer surface of the flow nipple 3 is substantially cylindrical and is formed with fiat portions 3b and 3b, thereby enabling to adapt thereto an injection syringe of conventional type, for example by receiving the syringe in the flow nipple.
According to a modification or alternative embodiment, a flow nipple may be provided, for example of the Luer-Lock type, to allow the adaptation of a syringe having a fiow nipple of corresponding construction, the fiow nipple having a suitable locking means which achieves a locked connection between the disc 2 and the injection syringe.
On the secondary flow nipples 4 to 10 are adaptable injection needles which are inserted inside of these flow nipples;
these needles are for example 3 mm. long as to the useful length, ie beyond the flow nipple.
The device of FIGS. 1 to 3 is remarkably interesting in mesotherapy; in addition, it may be noted that, due to its construction, it enables a directional effect of each injection needle more precise or accurate than that obtained with the usual injection needles (greater stability of a conventional injection syringe provided with a single needle).
The aforesaid distributor is desirably made of plastic or metallic material, for example from stainless steel; it could also be made from a synthetic material or other suitable material.
This distributor, in particular when it is made from plastic material, may or not be disposed of after each operation.
FIGS. 4 and 5 show a distributor the body of which has the shape of an elongated rectangular parallelepiped 18 provided on one of its sides or faces with a main flow nipple 19 and on the other side or face with seven secondary flow nipples ll, 12, 13, 14, 15, 16 and 17, connected through short transverse channels or ducts 11a to 170, respectively, to a longitudinal duct 20 fed by an axial channel or duct 19a of the nipple 19; it should be noted that the diameters of the ducts or channels increase on the one hand according to the order of succession 14a, 13a, 12a and 11a and on the other hand according to the order of succession 14a, 15a, 16a and 17a. thereby enabling upon taking into account the dissymmetry of feed or supply of injection liquid, nevertheless to achieve substantially equal flow rates at the level of the secondary flow nipples 11 to 17.
It is understood that the invention should not be limited to the forms of embodiments described and shown which have been given by way ofexamples only. In particular, it comprises all the means constituting technical equivalents of the means described as well as their combinations if the latter are carried out according to the gist ofthe invention.
What I claim is:
l. A device for simultaneous injection of a liquid at a plurality of points of a given area, wherein the improvement consists in that it comprises a distributor consisting of a body, at least one main flow nipple connectable to an injection syringe, a plurality of secondary flow nipples connectable to injection needles and a network of ducts provided within said body for distributing said injection liquid, said distributor body having the shape ofa substantially flat cylindrical disc on one side of which is located said main flow nipple whereas said secondary flow nipples are located on the other side thereof, said network consisting of substantially radial ducts, said radial ducts communicating with said secondary flow nipples through short substantially axial passageways, whereas said ducts extend to the periphery of said disc where they are adapted to be opened so as to enable their cleaning, removable closure means being provided at the outer ends of said radial ducts.

Claims (1)

1. A device for simultaneous injection of a liquid at a plurality of points of a given area, wherein the improvement consists in that it comprises a distributor consisting of a body, at least one main flow nipple connectable to an injection syringe, a plurality of secondary flow nipples connectable to injection needles and a network of ducts provided within said body for distributing said injection liquid, said distributor body having the shape of a substantially flat cylindrical disc on one side of which is located said main flow nipple whereas said secondary flow nipples are located on the other side thereof, said network consisting of substantially radial ducts, said radial ducts communicating with said secondary flow nipples through short substantially axial passageways, whereas said ducts extend to the periphery of said disc where they are adapted to be opened so as to enable their cleaning, removable closure means being provided at the outer ends of said radial ducts.
US799673A 1968-02-20 1969-02-17 Device for simultaneously injecting a liquid at a plurality of injection points Expired - Lifetime US3595231A (en)

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US3814097A (en) * 1972-02-14 1974-06-04 Ici Ltd Dressing
US3918449A (en) * 1973-06-06 1975-11-11 Guerin A Ets Device for cutaneous therapeutic treatment
US3941126A (en) * 1974-08-08 1976-03-02 Dietrich Joseph W Apparatus for long term intravenous administration of diluted incompatible multiple medications
US4191183A (en) * 1977-10-31 1980-03-04 Barry Mendelson Mixing chamber for use in plural medical liquid intravenous administration set
US4360435A (en) * 1979-11-01 1982-11-23 Baxter Travenol Laboratories, Inc. Process for sterilizing and transferring a solution
US4372100A (en) * 1979-11-01 1983-02-08 Baxter Travenol Laboratories, Inc. Process and apparatus for compounding hyperalimentation solutions
US4452600A (en) * 1979-05-01 1984-06-05 Schachar Ronald A Cornea endothelial protection method
EP0167662A2 (en) * 1983-10-10 1986-01-15 Mario Aluigi Multi-needle syringe for filling through a barrel plunger, particularly useful in mesotherapy
US4586490A (en) * 1984-02-27 1986-05-06 Katz Harry R Needle inserting instrument means for interstitial radiotherapy
EP0205915A1 (en) * 1985-05-21 1986-12-30 Mario Aluigi A multi-needle plate unit with point-saving case for mesotherapeutical use
US5207643A (en) * 1991-05-08 1993-05-04 Ballard Medical Products Multi-lumen-catheter flow valve system
US5290258A (en) * 1992-07-27 1994-03-01 Genesis Industries, Inc. Syringe for administering sequentially multiple doses of a medicament
US5846225A (en) * 1997-02-19 1998-12-08 Cornell Research Foundation, Inc. Gene transfer therapy delivery device and method
WO2000054827A1 (en) * 1999-03-15 2000-09-21 Powderject Research Limited Needleless syringe
EP1086718A1 (en) * 1999-09-22 2001-03-28 Becton Dickinson and Company Method and apparatus for the transdermal administration of a substance
US6322536B1 (en) 1998-03-06 2001-11-27 Cornell Research Foundation, Inc. Minimally invasive gene therapy delivery and method
US20020082543A1 (en) * 2000-12-14 2002-06-27 Jung-Hwan Park Microneedle devices and production thereof
US6508802B1 (en) 2000-05-23 2003-01-21 Cornell Research Foundation, Inc. Remote sensing gene therapy delivery device and method of administering a therapeutic solution to a heart
US6518255B2 (en) 1997-01-29 2003-02-11 Cornell Research Foundation, Inc. Multiple site delivery of adenoviral vector directly into muscle for the induction of angiogenesis
US20030130624A1 (en) * 2002-01-07 2003-07-10 Kowalik Francis C. Medical infusion system with integrated power supply and pump therefor
US6592545B1 (en) 1994-12-23 2003-07-15 Powderject Research Limited Particle delivery
WO2003066126A2 (en) 2002-02-04 2003-08-14 Becton, Dickinson And Company Dermal access member
US20030187423A1 (en) * 2002-04-02 2003-10-02 Wilkinson Bradley M. Valved intradermal delivery device and method of intradermally delivering a substance to a patient
US20030187394A1 (en) * 2002-04-02 2003-10-02 Wilkinson Bradley M Method and device for intradermally delivering a substance
US6629949B1 (en) * 2000-05-08 2003-10-07 Sterling Medivations, Inc. Micro infusion drug delivery device
US6659982B2 (en) 2000-05-08 2003-12-09 Sterling Medivations, Inc. Micro infusion drug delivery device
US6716190B1 (en) * 2000-04-19 2004-04-06 Scimed Life Systems, Inc. Device and methods for the delivery and injection of therapeutic and diagnostic agents to a target site within a body
US20050277887A1 (en) * 2000-05-08 2005-12-15 Joel Douglas Micro infusion drug delivery device
US20070225676A1 (en) * 1999-06-04 2007-09-27 Prausnitz Mark R Microneedle drug delivery device
US20070265570A1 (en) * 2006-04-27 2007-11-15 Gerut Zachary E Device and method for treating skin prior to performing surgery
US20100312191A1 (en) * 1998-06-10 2010-12-09 Georgia Tech Research Corporation Microneedle Devices and Methods of Manufacture and Use Thereof
US20110046556A1 (en) * 2009-08-22 2011-02-24 Joseph Wayne Kraft Rapid Local Anesthesia Injection Cone
US20110137250A1 (en) * 2009-08-22 2011-06-09 Joseph Wayne Kraft Rapid Local Anesthesia Linear Injection Device
US20170173318A1 (en) * 2004-04-12 2017-06-22 Allergan, Inc. Multi-site injection system
US20180264204A1 (en) * 2017-01-26 2018-09-20 Allergan Industrie Sas Needle array device
US10433928B2 (en) 2015-03-10 2019-10-08 Allergan Pharmaceuticals Holdings (Ireland) Unlimited Company Multiple needle injector
USD865950S1 (en) 2017-03-24 2019-11-05 Allergan, Inc. Syringe device
USD868246S1 (en) * 2017-07-28 2019-11-26 Asti Corporation Microneedle array
US10575897B2 (en) 2004-04-01 2020-03-03 The General Hospital Corporation Method and apparatus for dermatological treatment and tissue reshaping
US10596321B2 (en) 2016-04-08 2020-03-24 Allergan, Inc. Aspiration and injection device
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FR447368A (en) * 1912-08-19 1912-12-31 Marcel Mairesse Prickle injector for intra-dermal medicating revulsion
US1496126A (en) * 1922-06-09 1924-06-03 Joseph W Livingstone Syringe
US2551902A (en) * 1948-09-10 1951-05-08 Arthur Schaffer Dehorning fluid ejector
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Cited By (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3814097A (en) * 1972-02-14 1974-06-04 Ici Ltd Dressing
US3918449A (en) * 1973-06-06 1975-11-11 Guerin A Ets Device for cutaneous therapeutic treatment
US3941126A (en) * 1974-08-08 1976-03-02 Dietrich Joseph W Apparatus for long term intravenous administration of diluted incompatible multiple medications
US4191183A (en) * 1977-10-31 1980-03-04 Barry Mendelson Mixing chamber for use in plural medical liquid intravenous administration set
US4452600A (en) * 1979-05-01 1984-06-05 Schachar Ronald A Cornea endothelial protection method
US4360435A (en) * 1979-11-01 1982-11-23 Baxter Travenol Laboratories, Inc. Process for sterilizing and transferring a solution
US4372100A (en) * 1979-11-01 1983-02-08 Baxter Travenol Laboratories, Inc. Process and apparatus for compounding hyperalimentation solutions
EP0167662A3 (en) * 1983-10-10 1986-08-27 Mario Aluigi Multi-needle syringe for filling through a barrel plunger, particularly useful in mesotherapy
EP0167662A2 (en) * 1983-10-10 1986-01-15 Mario Aluigi Multi-needle syringe for filling through a barrel plunger, particularly useful in mesotherapy
US4586490A (en) * 1984-02-27 1986-05-06 Katz Harry R Needle inserting instrument means for interstitial radiotherapy
EP0205915A1 (en) * 1985-05-21 1986-12-30 Mario Aluigi A multi-needle plate unit with point-saving case for mesotherapeutical use
US5207643A (en) * 1991-05-08 1993-05-04 Ballard Medical Products Multi-lumen-catheter flow valve system
US5290258A (en) * 1992-07-27 1994-03-01 Genesis Industries, Inc. Syringe for administering sequentially multiple doses of a medicament
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DE1907296A1 (en) 1969-09-11
FR1584474A (en) 1969-12-26

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