|Publication number||US3565074 A|
|Publication date||23 Feb 1971|
|Filing date||24 Apr 1969|
|Priority date||24 Apr 1969|
|Publication number||US 3565074 A, US 3565074A, US-A-3565074, US3565074 A, US3565074A|
|Inventors||Foti Philip R|
|Original Assignee||Becton Dickinson Co|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (5), Referenced by (119), Classifications (4)|
|External Links: USPTO, USPTO Assignment, Espacenet|
United States Patent  Inventor Philip R. Foti FOREIGN PATENTS K Hawaii 1,092,011 11/1954 France 128/214.4 pp 31 1 1969 646,559 6/1937 Germany 128/221 g gg 1971 Primary Examiner-Dalton L. Truluclc  Assignee Becton, Dickinson and Company Attorney-Kane, Dals1mer, Kane, Sullivan and Kurvcz East Rutherford, NJ.
ABSTRACT: An indwelling arterial cannula assembly includes a plastic catheter coaxially removably mounted on a blunt tipped cannula having a pointed stylet removably located in the bore thereof and extended beyond the blunt tip of the cannula; and a method is provided for positioning a por-  INDWELLING ARTERIAL CANNULA ASSEMBLY tion of the plastic catheter of the assembly into an artery. The 10 Claims 7 Drawing Figs. method includes the steps of pro ecting the assembly into the artery by p1erc1ng both the inner and outer walls of the artery m 128,214.49 with the point of the stylet and extending a portion of the as- 128/221 sembly through the openings in both of the walls. Then the Int. C A61"! 5/00 stylet is removed from the assembly and the remainder of the  Field ofSearch assemlfly is retracted until its forward tip reenters the artery 10- g 348 and fluid from the artery flows through the cannula. The remainder of the assembly is then advanced into the lumen of  References cued the vessel to the desired position with the blunt tip of the can- UNITED STATES PATENTS nula alleviating the danger of repuncture of the inner wall of 2,389,355 1 H1945 Goland et al. l28/2l4.4 the artery. Finally, the plastic catheter is slid forward while the 3,030,953 4/1962 Koehn 128/221X cannula is removed therefrom which thereby locates a portion 3,312,220 4/1967 Eisenberg l28/2l4.4 of the catheter in the desired position in the artery.
' i 1 A 1 V 33 25 PATENTEDFEB23|91| 3565074 sumanrg INVENTOR PH/A/P .Q =p
ATTORNEYS There are several different types of arterial indwelling needles in use today; However, these needles produce various shortcomings when is use which demand the development of an improved indwelling arterial cannula assembly for application to a patient.
For example, one type of needle in use is awell-known Coumand needle. This type of needle is generally considered as the original arterial indwelling needle and it is constructed of all steel materials. Therefore, when it is placed within the lumen of a vessel which is located in a portion of the body where considerable movement occurs which is often the case, extensive damage to the vessel could occur. This happens 'quite often since this type of needleis generally placed in an area where considerable flexing by the patient would normally occur such as adjacent the elbow. Consequently, this type of needle is difficult to-leave in place for many hours or days as is often necessary.
Several other attempts have been made to produce a needle which will satisfy the requirements for providing an indwelling catheter for an artery located in a difficult position such as discussed above. For example, one combination employs a plastic catheter positioned on a pointed needle which contains a pointed stylet within its opening with the solid pointed end of the stylet being aligned with the pointed end of the needle. The difficulty with this type of arrangement is that it is very difficult to get into an artery because of the pointed cannula or needle that remains when'the stylet is removed. Trying to slide the plastic catheter and needle combination along the interior walls of the vessel particularly if the vessel is located in a difticult position such as an elbow joint will often cause repeated punctures of the vessel and considerable damage.
Another problem with this type of needle is that the stylet and the pointed cannula are generally beveled and have a common type of needle tapered" point. This presents a problem in the instance of small and thin artery walls where it is preferable to have a cleaner puncture to alleviate the danger of tearing the artery wall which of'course-causes unwanted damage and also discomfort to the patient. Of course the one feature that this type of needle assembly has that the Cournand assembly does not have is the fact that it leaves a flexible catheter in the artery instead of a stiff steel needle as in the instance of the Cournand.
A further problem which often appears with existing needle assemblies is that often the assembly does not slip easily into place within the artery once the initial puncture is made. Furthermore, there is often difficulty in sliding an obturator in and out of the plastic catheter when it is in position within the artery each time it is desired to pass fluid the through the catheter. A catheter material which will facilitate this particular step would also be advantageous in construction of the needle assembly. Once again this also provides a catheter ar- SUMMARY OF THE INVENTION Principally it is an objective of this invention to alleviate the above discussed problems existent with presently used needles and to provide a needle assembly which will achieve the above mentioned advantageous features as well as satisfying the above discussed requirements. The present indwelling arterial cannula assembly is capable of easier placement thereby providing a higher success rates in any users hands. The resultant catheter is designed so as to be more comfortable in place because of flexibility thereby avoiding patient immobilization. This allows one to leave such a catheter in place for comparatively long periods of time, for example, in an intensive care unit, The introduction of the assembly and catheter in its proper location is significantly less traumatic to the patient and the assembly is readily adaptable for use in routine pulmonary physiological studies, cardiac output determinations and monitoring, indwelling arterial electrode use for monitoring partial pressure of oxygen, and any procedure requiring easy access to intermittent arterial blood samples over an extended period of time. The technique and method of use of the assembly is easily taught and the assembly is applicable to children as well as adults.
A brief description of the structural features of the indwelling arterial cannula assembly disclosed herein and its method of application is now in order to generally point out how the above mentioned features andv objectives are obtained. An indwelling arterial cannula assembly is provided for the positioning of a portion of a plastic catheter into an artery wherein the assembly includes a plastic catheter coaxially removably mounted on ;a blunt tipped cannula having a pointed stylet removably located in the bore thereof and extending beyond the blunt tip of the cannula. The method of use of this assembly includes projecting the assembly into the artery by piercing both the outer and inner walls of the artery with the point of the stylet and extending a portion of the assembly through the openings in both walls of the artery. The stylet is then removed from the assembly and the remainder of the assembly is retracted until the forward tip thereof reenters the artery and fluid from the artery flows through the cannula.
rangement which is less traumatic and discomforting to patients.
Other features which would be advantageous in an assembly of this type would be to have the outer catheter arranged so that it has a smooth taper from its forward point to its extreme diameter to facilitate entrance within the artery. Furthermore, an assembly of smaller gauges than previously utilized would facilitate use in smaller more difficult arteries within the patient. Furthermore, a tip on the assembly which ishard as well as having the above advantages would be helpful in that it will not hang up on the artery wall when entering. This is often the problem with previously discussed assemblies of this type.
Finally, a catheter should be constructed of a material, if
The remainder of the assembly is then advanced into the lumen of the artery to the desired position with the blunt tip of the cannula alleviating the danger of repuncture of the inner wall of the artery. Finally, the plastic catheter is slid forward while removing the cannula therefrom which thereby locates a portion of the catheter in the desired position within the artery.
With the above objectives in mind, reference is had to the attached drawing for a more detailed description.
BRIEF DESCRIPTION OF THE DRAWINGS DESCRIPTION OF THE PREFERRED EMBODIMENT Initially, discussion will be directed'toward the cannula assembly 20 itself as attention is directed to FIGS. 1 and 2 of the drawings. Assembly 20 is composed of three basic elements, a stylet 21, a cannula 22 and a catheter 23.
Stylet 21 may be constructed of any well-known material to give it its solid properties such as a rigid metallic wire material. The forward end of the stylet 21 has a sharp pointed tip 24 to facilitate the assurance that only tiny pin holes are made in the vessel or artery of the patient during the puncture procedure. The rear end of stylet 21 has affixed thereto a hub 25 generally constructed of any common rigid material.
Cannula 22 is also a rigid member and may be constructed of any common type of rigid material, for example a metallic material such as stainless steel. The forward tip 26 of the cannula 22 is blunted and has a somewhat rounded configuration so that cannula 22 will follow stylet 21 through a puncture hole in an artery but which is not sharp enough to readily create a new puncture by itself. Mounted on the rear end of the cannula 22 by any common means or integral therewith is a hub 27. An axial bore 28 extends from the forward tip 26 of the cannula 22 to the rear end thereof and communicates with an opening 29 within hub 27 to provide a continuous passage through cannula 22. Bore 28 is designed to accommodate in close fitting relationship stylet 21 with the forward portion of hub 25 positioned within opening 29 in hub 27. When stylet 21 is thus positioned within cannula 22 the forward tip 24 thereof will extend beyond tip 26 of cannula 22 a predetermined distance. Satisfactory results have been obtained with such as assembly when stylet 21 extends approximately 4 mm. beyond the blunt tip 26 of the cannula 22. However, this is not necessarily required and this distance may be varied depending upon the individual circumstances of use for the assembly The third principal element of assembly 20 is catheter 23 which generally has a taper from its rear end to its forward tip 30. This taper is to facilitate entrance of the catheter 23 through the puncture created in an artery when assembly 20 in introduced therein as will be readily apparent below. At the rear end of catheter 23 either attached thereto by common means or integral therewith is a hub 31. An axial bore 32 extends from the tip 30 of catheter 23 rearwardly into communication with an opening 33 in hub 31 to combine therewith to form a continuous passage from one end of catheter 23 to the other. Bore 32 and catheter 23 is of a sufi'rcient size to snugly accommodate cannula 22 when assembly 20 is formed and opening 33 in hub 31 is designed to accommodate the forward portion of hub 27 of cannula 22. In this manner, stylet 21, cannula 22 and catheter 23 may be assembled in coaxial relationship to form indwelling arterial cannula assembly 20. The configuration of each hub and bore of each element contribute to an interlocking relationship between the elements in assembled form as is readily apparent from FIG. 2.
Cannula 23 is generally constructed of a plastic material, preferably flexible, which will be inert with the portions of the body with which it comes in contact and which will readily accommodate itself to the arterial configuration into which it must extend. It also must be of a material which will readily permit it to be introduced through the opening provided by tip 24 and tip 26 in the arterial walls with the minimum amount of resistance. A material which has been found to be particularly effective for use as catheter 23 is polytetrafluoroethylene which is commonly known as Teflon. As is well known in the art, Teflon is inert to the portions of the body with which it will come in contact as well as the fluids with which it will come in contact. Furthermore, Teflon being a natural lubricating material will easily follow its predecessor needle portions of the assembly into the arterial opening. Other plastic materials have been found to operate successfully, but not as successful as Teflon when fonned as catheter 23 such as polyvinyl chloride with a silicone lubricated inner bore and which is welded to hub 31. Several important features of the catheter 23 which contribute to the ease with which the assembly may be operated, is the fact that the catheter should contain a smooth taper from its rear end to its forward tip, should fit tightly on cannula 22 yet still be easily removable therefrom and the plastic employed should be such that the tip may be electromatically buffed, if desired, to increase hardness and to alleviate the danger of "hang up" of the artery wall when it enters the artery. Previously known cannula assemblies of this type have produced this problem.
The term hang up refers to a catching of the forward edge of the catheter on some portion of the artery as it is moved with respect thereto which could cause tearing of the artery structure itself in resultant damage and discomfort to the patient. Furthermore, the material used for catheter 23 should be a disposable type of material so that the assembly may be economically and easily manufactured at low cost. The above discussed materials satisfy these requirements as well as other materials which are known in the a It should be noted as can be readily seen from FIG. 2 that the smooth rather continuous engagement formed by tip 24 of stylet 21, tip 26 of cannula 22 and tip 30 of catheter 23 facilitates the entrance and movement of theassembly within the arterial area during operation. In this regard it should be pointed out that tip 30 does not extend into coincidence with tip 26 of cannula 22 but tenninates a somewhat short distance therefrom. This contributes to lessening the danger of hang up" as well as limiting the extent of tolerances required during manufacture and thereby facilitating the production of an economic cannula assembly.
Turning to the operation and use of the assembly itself, reference should be made to FIGS. 3-7 which shows the sequence of steps employed in positioning catheter 23 properly within an artery 34. A recommended technique for insertion would be as follows: Initially, the vessel to be entered should be locally anesthetized. Then if desired, scape] blade puncture of the skin is useful to avoid resistance to easy manipulation while transfixing the underlying vessel or artery.
If palpitating fingers are placed above and below the site of arterial puncture, the following procedure aids in accurate, atraumatic cannulation of the vessel, that is, to advance the long needle stylet 21 through both walls somewhat tangentially. If it is placed nearly square through the center of the lumen, slight pressure will cause the blunt metallic cannula 22 to compress the arterial wall, compromise the lumen and the distal pulse will disappear or become markedly attenuated. A release of slight pressure will bring back the pulse. This is a sure sign of proper placement and the assembly 20 may then be advanced through both the outer wall 35 and the inner wall 36 of vessel 34. If the described sign is not obtained, it is best to withdraw completely, to begin again, and only pin holes are left in vessel 34 principally due to the sharp point 24 on stylet 21.
Once vessel 34 is transfixed and the entire assembly 20 has extended through both walls of vessel 34, then stylet 21 may be removed from the assembly. The remainder of assembly 20 should then be retracted until the tip 26 of cannula 22 has reentered the vessel which will be indicated by flow of fluid being established so that it issues from hub 27 of cannula 22. This position is indicated by FIG. 5 of the drawing. It should be noted at this point that inner wall 36 of artery 34 will tend to close and seal once again at the original point of puncture 37.
The next step is to advance the remainder of assembly 20 into the lumen of artery 34 to the desired degree. As illustrated in FIG. 6, the blunt tip 26 on cannula 22 will facilitate this movement in the sense that it will allow the assembly to move through the vessel without danger of tearing or repuncturing the inner wall of vessel 34.
The final step as illustrated in FIG. 7 is to simply slide the plastic catheter 23 forward and remove blunt cannula 22 rearwardly at the same time to properly locate catheter 23 within the lumen of the artery 34 where it will assume the natural configuration of the artery and may be kept in that position for a considerable length of time. A plastic style! or obturator may be placed into the lumen of the needle to keep it from clotting between blood samples or if the catheters course is too tortuous, a syringe with anticoagulant may be attached thereto. A common type of Teflon or obturator may be sued used to occlude the Teflon catheter lumen since it will not clot and flow will be maintained well. It is further recommended that a sterile glove be used for intermittent sampling, especially with smaller needles, to avoid contamination of the obturator shafl.
Obturators of this typeare common as well as the use of a syringe with an anticoagulant which may-be attached to the hub of the catheter. Therefore, since these items are not part of the assembly itself they are not shown in the drawings for simplicity purposes. Assemblies of this type may remain in place for a considerable length of time without thromboembolic or other problems and with a minimum of patient discomfort.
The advantages of such an assembly as disclosed herein are readily apparent and include easier placement of an indwelling arterial catheterand higher success rates in any hands. Furthermore, they are more comfortable when placed in a difficult position because of the flexible features possible thereby avoiding patient immobilization. This allows one to leave such a catheter in place for comparatively long periods of time, for example, in an intensive care unit. It isrreadily apparent that from the ease of and simplicity of construction, the utilization of the assembly is significantly less traumatic. for the patient and the assembly is readilyadaptable for use in routine pulmonary physiological studies, cardiac output determinations and monitoring, indwelling arterial electrode use for monitoring partial pressure of oxygen, on-line arterial pressure monitoring, and any procedure requiring easy access to intermittent arterial blood samples over an extended period of time. As
discussed above, the technique of use is easily taught and the assembly is equally applicable to children as well as adults.
Thus, the above mentioned objects of the invention, among others, are achieved.
1. An indwelling arterial cannula assembly comprising:
a rigid cannula having a blunted forward tip, a hub connected to its rear end and a passage therethrough;
a plastic catheter having a passage therethrough, a hub connected to its rear end and being coaxially removably mounted on said cannula said catheter being shorter in length than said cannula; and l a stylet having a pointed forward end, a hub attached to its rear end and being removably positioned within the passage of said cannula with its forward end portion extending beyond the blunted tip of said cannula thereby facilitating the positioning of a portion of said assembly into an artery and the subsequent removal of said cannula and stylet from said catheterto leave a portion of said plastic catheter in the desired position within said artery.
2. The invention in accordance with-claim 1 wherein the forward portion of said catheter tapers. inwardly toward the forward end thereof and terminates to the rear of the blunt tip of said cannula to facilitate entrance of said assembly into said artery.
3. The invention in accordance with claim 1 wherein said cannula is composed of a metallic material.
4. The invention in accordance with claim 1 wherein said pointed stylet is composed of a metallic material.
5. The invention in accordance with claim 1 wherein said catheter is composed of polytetrafluoroethylene.
6. The invention in accordance with claim 1 wherein said cannula is rounded at its blunted tip end.
7. The invention is accordance with claim 1 wherein said printed stylet extends 4 mm. beyond the blunted tip of said cannula.
8. A method of positioning into an artery a portion of a plastic catheter of an indwelling arterial cannula assembly including a plastic catheter coaxially removably mounted on a blunt tipped, rigid cannula having a pointed stylet removably located in the bore thereof and extending beyond the blunt tip of the cannula said catheter being shorter in length than said cannula comprising;
projecting said assembly into the artery by piercing both the outer and inner wallsof the artery with the point of said stylet and extending a portion of said assembly through the openings in the walls of said artery;
removing the stylet from said assembly;
retracting the remainder of said assembly until the forward tip thereof reenters the artery and fluid from said artery flows through said cannula; advancing the remainder of said assembly into the lumen of the artery to the desired position with the blunt tip of said cannula alleviating the danger of repuncture of the inner wall of the artery; and sliding the plastic catheter forward while removing the cannula therefrom thereby locating a portion of the catheter in the desired position in the artery. 9. The invention in accordance with claim 8 wherein after said cannula is removed from said catheter a plastic obturator is placed into the lumen of the catheter to alleviate the danger of clotting between the taking of samples of fluid from the artery.
10. The invention in accordance with claim 8 after said cannula is removed from said catheter a syringe containing an anticoagulant substance may be attached to the rear end of the catheter to alleviate the danger of clotting between the taking of samples of fluid from the artery.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US2389355 *||27 Jan 1943||20 Nov 1945||Althea D Kessler||Surgical needle|
|US3030953 *||17 Oct 1957||24 Apr 1962||Koehn Wilbur R||Apparatus for applying catheter|
|US3312220 *||2 Apr 1963||4 Apr 1967||Eisenberg Myron Michael||Disposable indwelling plastic cannula assembly|
|DE646559C *||5 Jun 1935||17 Jun 1937||Brynjulf Ingebrigtsen||Punktionsnadel|
|FR1092011A *||Title not available|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3792703 *||10 Jul 1972||19 Feb 1974||Deseret Pharma||Catheter placement unit|
|US3856009 *||29 May 1973||24 Dec 1974||Johnson & Johnson||Catheter placement unit|
|US4308875 *||11 Mar 1981||5 Jan 1982||Universal Medical Instrument Corporation||Amniocentesis needle|
|US4327722 *||20 Aug 1979||4 May 1982||Groshong Leroy E||Methods and apparatus for intravenous therapy and hyperalimentation|
|US4509534 *||14 Jun 1982||9 Apr 1985||Tassin Jr Myron J||Blood withdrawal apparatus and method of using same|
|US4535773 *||26 Mar 1982||20 Aug 1985||Inbae Yoon||Safety puncturing instrument and method|
|US4581019 *||22 Apr 1982||8 Apr 1986||Curelaru Johan||Device for introducing a catheter-cannula into a blood vessel|
|US4643712 *||18 Oct 1985||17 Feb 1987||Blagoveschensky Gosudarstvenny Meditsinsky Institut||Aortic cannula|
|US4699611 *||19 Apr 1985||13 Oct 1987||C. R. Bard, Inc.||Biliary stent introducer|
|US4804365 *||13 Feb 1987||14 Feb 1989||C. R. Bard||Vascular cannulae for transfemoral cardiopulmonary bypass and method of use|
|US4995866 *||15 Dec 1989||26 Feb 1991||Microvena Corporation||Combined needle and dilator apparatus|
|US5160325 *||22 Jan 1991||3 Nov 1992||C. R. Bard, Inc.||Catheter with novel lumens shapes|
|US5226426 *||18 Dec 1990||13 Jul 1993||Inbae Yoon||Safety penetrating instrument|
|US5232442 *||26 Dec 1991||3 Aug 1993||Brigham And Women's Hospital||Method and apparatus for inducing anesthesia|
|US5242410 *||23 Apr 1992||7 Sep 1993||University Of Florida||Wireless high flow intravascular sheath introducer and method|
|US5304141 *||31 Dec 1990||19 Apr 1994||Brigham And Women's Hospital||Method and apparatus for inducing anesthesia|
|US5401247 *||6 Jan 1994||28 Mar 1995||Yoon; Inbae||Safety penetrating instrument|
|US5458579 *||25 Nov 1992||17 Oct 1995||Technalytics, Inc.||Mechanical trocar insertion apparatus|
|US5522832 *||26 Jan 1994||4 Jun 1996||Terumo Kabushiki Kaisha||Blood vessel piercing instrument|
|US5538509 *||31 Jan 1994||23 Jul 1996||Richard-Allan Medical Industries, Inc.||Trocar assembly|
|US5549564 *||7 Jun 1993||27 Aug 1996||Yoon; Inbae||Safety penetrating instrument|
|US5569288 *||6 Jan 1994||29 Oct 1996||Yoon; Inbae||Safety penetrating instrument|
|US5584812 *||16 Dec 1994||17 Dec 1996||Stonefield Medical Products, Inc.||Closed intravenous system|
|US5586991 *||6 Jan 1994||24 Dec 1996||Yoon; Inbae||Safety penetrating instrument|
|US5855566 *||1 Jun 1995||5 Jan 1999||Urohealth, Inc. (California)||Trocar assembly|
|US5941852 *||1 Jun 1995||24 Aug 1999||Imagyn Medical Technologies California, Inc.||Trocar assembly|
|US6156010 *||17 Jun 1998||5 Dec 2000||Injectimed, Inc.||Method and apparatus for introducing an intravenous catheter|
|US6558353 *||25 Jan 2001||6 May 2003||Walter A. Zohmann||Spinal needle|
|US6607511 *||9 Aug 2001||19 Aug 2003||Mdc Investment Holdings, Inc.||Medical device with safety flexible needle|
|US7025746||24 Dec 2002||11 Apr 2006||Yale University||Vascular access device|
|US7156836 *||19 Apr 2001||2 Jan 2007||Richard Keng Siang Teo||Cannula assembly|
|US7206642 *||22 Apr 2002||17 Apr 2007||Medtronic, Inc.||Implantable lead with improved stylet lumen|
|US7722567||21 Dec 2005||25 May 2010||Yale University||Access device|
|US7740598||1 Mar 2007||22 Jun 2010||C. R. Bard, Inc.||Coaxial cannula provided with a sealing element|
|US7762961||29 Mar 2004||27 Jul 2010||C. R. Bard, Inc.||Pressure generating unit|
|US7828747||1 Mar 2007||9 Nov 2010||C. R. Bard, Inc.||Pressure generating unit|
|US7856707||11 Apr 2003||28 Dec 2010||Medtronic, Inc.||Method for performing a coplanar connection between a conductor and a contact on an implantable lead|
|US7922696||24 Jan 2008||12 Apr 2011||Access Scientific, Inc.||Access device|
|US7953496||11 Apr 2003||31 May 2011||Medtronic, Inc.||Implantable lead with isolated contact coupling|
|US8000802||22 Apr 2002||16 Aug 2011||Medtronic, Inc.||Implantable lead with coplanar contact coupling|
|US8002713||5 Mar 2003||23 Aug 2011||C. R. Bard, Inc.||Biopsy device and insertable biopsy needle module|
|US8012102||1 Mar 2007||6 Sep 2011||C. R. Bard, Inc.||Quick cycle biopsy system|
|US8016772||1 Mar 2007||13 Sep 2011||C. R. Bard, Inc.||Biopsy device for removing tissue specimens using a vacuum|
|US8052614||30 Dec 2009||8 Nov 2011||C. R. Bard, Inc.||Biopsy device having a vacuum pump|
|US8052615||8 Jul 2005||8 Nov 2011||Bard Peripheral Vascular, Inc.||Length detection system for biopsy device|
|US8075529||18 Dec 2007||13 Dec 2011||Medikit Co., Ltd.||Indwelling needle assembly|
|US8083720 *||13 May 2008||27 Dec 2011||Solar Matthew S||Device and method for delivering therapeutic agents to an area of the body|
|US8105286 *||18 Apr 2008||31 Jan 2012||Access Scientific, Inc.||Access device|
|US8109885||17 Mar 2003||7 Feb 2012||C. R. Bard, Inc.||Biopsy device for removing tissue specimens using a vacuum|
|US8157744||8 Jul 2005||17 Apr 2012||Bard Peripheral Vascular, Inc.||Tissue sample flushing system for biopsy device|
|US8162851||5 Oct 2010||24 Apr 2012||C. R. Bard, Inc.||Biopsy needle system having a pressure generating unit|
|US8172773||1 Mar 2007||8 May 2012||C. R. Bard, Inc.||Biopsy device and biopsy needle module that can be inserted into the biopsy device|
|US8192402||18 Apr 2008||5 Jun 2012||Access Scientific, Inc.||Access device|
|US8202251||13 Mar 2009||19 Jun 2012||Access Scientific, Inc.||Access device|
|US8251917||17 Aug 2007||28 Aug 2012||C. R. Bard, Inc.||Self-contained handheld biopsy needle|
|US8262585||10 Aug 2006||11 Sep 2012||C. R. Bard, Inc.||Single-insertion, multiple sampling biopsy device with linear drive|
|US8262586||23 Oct 2007||11 Sep 2012||C. R. Bard, Inc.||Large sample low aspect ratio biopsy needle|
|US8267868||10 Aug 2006||18 Sep 2012||C. R. Bard, Inc.||Single-insertion, multiple sample biopsy device with integrated markers|
|US8282574||10 Aug 2006||9 Oct 2012||C. R. Bard, Inc.||Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers|
|US8306631||5 Aug 2011||6 Nov 2012||Medtronic, Inc.||Implantable lead with coplanar contact coupling|
|US8333734||3 Jul 2003||18 Dec 2012||Walter A. Zohmann||Fenestrated peripheral nerve block needle and method for using the same|
|US8366636||8 Jul 2005||5 Feb 2013||Bard Peripheral Vascular, Inc.||Firing system for biopsy device|
|US8377005||30 Nov 2010||19 Feb 2013||Custom Medical Applications||Neural injection system and related methods|
|US8377006||11 Apr 2011||19 Feb 2013||Access Scientific, Inc.||Access device|
|US8382793 *||14 Jan 2003||26 Feb 2013||Radi Medical Systems Ab||Introducer sheath|
|US8386055||28 Apr 2011||26 Feb 2013||Medtronic, Inc.||Implantable lead with isolated contact coupling|
|US8430824||29 Oct 2009||30 Apr 2013||Bard Peripheral Vascular, Inc.||Biopsy driver assembly having a control circuit for conserving battery power|
|US8449503||30 Nov 2010||28 May 2013||Custom Medical Applications||Neural injection system and related methods|
|US8454532||11 Nov 2010||4 Jun 2013||Devicor Medical Products, Inc.||Clutch and valving system for tetherless biopsy device|
|US8485987||5 Oct 2007||16 Jul 2013||Bard Peripheral Vascular, Inc.||Tissue handling system with reduced operator exposure|
|US8485989||1 Sep 2009||16 Jul 2013||Bard Peripheral Vascular, Inc.||Biopsy apparatus having a tissue sample retrieval mechanism|
|US8504168||7 Dec 2010||6 Aug 2013||Medtronic, Inc.||Implantable lead with coplanar contact coupling|
|US8597205||17 Jul 2012||3 Dec 2013||C. R. Bard, Inc.||Biopsy device|
|US8597206||12 Oct 2009||3 Dec 2013||Bard Peripheral Vascular, Inc.||Biopsy probe assembly having a mechanism to prevent misalignment of components prior to installation|
|US8641677 *||21 Jan 2010||4 Feb 2014||James T. Rawls||Low-profile intravenous catheter device|
|US8657790||27 Oct 2011||25 Feb 2014||Access Scientific, Inc.||Access device with blunting device|
|US8672888||25 May 2010||18 Mar 2014||Yale University||Access device|
|US8690793||16 Mar 2009||8 Apr 2014||C. R. Bard, Inc.||Biopsy device having rotational cutting|
|US8702621||29 Apr 2011||22 Apr 2014||C.R. Bard, Inc.||Quick cycle biopsy system|
|US8702622||10 Aug 2011||22 Apr 2014||C.R. Bard, Inc.||Quick cycle biopsy system|
|US8708928||15 Apr 2009||29 Apr 2014||Bard Peripheral Vascular, Inc.||Biopsy apparatus having integrated fluid management|
|US8708929||12 Mar 2013||29 Apr 2014||Bard Peripheral Vascular, Inc.||Biopsy apparatus having integrated fluid management|
|US8708930||13 Mar 2013||29 Apr 2014||Bard Peripheral Vascular, Inc.||Biopsy apparatus having integrated fluid management|
|US8721563||28 Aug 2012||13 May 2014||C. R. Bard, Inc.||Single-insertion, multiple sample biopsy device with integrated markers|
|US8728003||28 Aug 2012||20 May 2014||C.R. Bard Inc.||Single insertion, multiple sample biopsy device with integrated markers|
|US8728004||12 Apr 2012||20 May 2014||C.R. Bard, Inc.||Biopsy needle system having a pressure generating unit|
|US8771200||22 Aug 2012||8 Jul 2014||C.R. Bard, Inc.||Single insertion, multiple sampling biopsy device with linear drive|
|US8808197||14 Mar 2013||19 Aug 2014||Bard Peripheral Vascular, Inc.||Biopsy driver assembly having a control circuit for conserving battery power|
|US8827958||12 May 2010||9 Sep 2014||Access Scientific, Llc||Access device with valve|
|US8845547||1 Dec 2009||30 Sep 2014||C. R. Bard, Inc.||Cannula provided with a sealing element for use in a medical procedure|
|US8845548||19 Apr 2012||30 Sep 2014||Devicor Medical Products, Inc.||Cutter drive assembly for biopsy device|
|US8858463||7 Nov 2013||14 Oct 2014||C. R. Bard, Inc.||Biopsy device|
|US8864680||8 Jul 2005||21 Oct 2014||Bard Peripheral Vascular, Inc.||Transport system for biopsy device|
|US8864682||1 May 2013||21 Oct 2014||Devicor Medical Products, Inc.||Clutch and valving system for tetherless biopsy device|
|US8882712||15 Jan 2013||11 Nov 2014||Custom Medical Applications||Neural injection system and related methods|
|US8900192||18 Jul 2011||2 Dec 2014||Access Scientific, Llc||Access device|
|US8915884||22 Jan 2013||23 Dec 2014||Access Scientific, Inc.||Access device|
|US8926527||27 Mar 2012||6 Jan 2015||Bard Peripheral Vascular, Inc.||Tissue sample flushing system for biopsy device|
|US8951208||13 Aug 2012||10 Feb 2015||C. R. Bard, Inc.||Self-contained handheld biopsy needle|
|US8951209||18 Apr 2012||10 Feb 2015||C. R. Bard, Inc.||Biopsy device and insertable biopsy needle module|
|US8956327||8 Feb 2011||17 Feb 2015||Access Scientific, Llc||Access device|
|US8961430||10 Sep 2012||24 Feb 2015||C.R. Bard, Inc.||Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers|
|US8992440||26 Sep 2011||31 Mar 2015||Bard Peripheral Vascular, Inc.||Length detection system for biopsy device|
|US9072502||29 Dec 2011||7 Jul 2015||C. R. Bard, Inc.||Disposable biopsy unit|
|US20040138674 *||14 Jan 2003||15 Jul 2004||Radi Medical Systems Ab||Introducer sheath|
|US20050004521 *||3 Jul 2003||6 Jan 2005||Zohmann Walter A.||Fenestrated peripheral nerve block needle and method for using the same|
|US20050165328 *||5 Mar 2003||28 Jul 2005||Norbert Heske||Biopsy device and biopsy needle module that can be inserted into the biopsy device|
|US20050203439 *||17 Mar 2003||15 Sep 2005||Norbert Heske||Vacuum biopsy device|
|US20080228149 *||16 Mar 2007||18 Sep 2008||Smiths Medical Asd, Inc.||Blunt cannula for accessing a slit septum|
|US20110178464 *||21 Jan 2010||21 Jul 2011||Rawls James T||Low-profile intravenous catheter device|
|CN100525850C||24 Dec 2002||12 Aug 2009||耶鲁大学||Vascular access device|
|EP0433717A1 *||28 Nov 1990||26 Jun 1991||B. Braun Melsungen AG||Instrument set for puncture|
|EP0608854A2 *||26 Jan 1994||3 Aug 1994||Terumo Kabushiki Kaisha||Blood vessel piercing instrument|
|EP1935447A1 *||14 Dec 2007||25 Jun 2008||Medikit Co., Ltd.||Indwelling needle assembly|
|EP2740422A1||5 Dec 2012||11 Jun 2014||Custom Medical Applications||Safety neural injection system and related methods|
|WO1982003003A1 *||2 Nov 1981||16 Sep 1982||Ruperto S Young||An amniocentesis needle|
|WO1983000429A1 *||2 Aug 1982||17 Feb 1983||Electro Catheter Corp||Catheter-needle assembly and method for drainage of fluid collections|
|WO1993014710A1 *||29 Jan 1993||5 Aug 1993||Al Rawi Muthafar Muflih||Fine gauge needles and cannulae|
|WO2003057272A2 *||24 Dec 2002||17 Jul 2003||Michael Tal||Vascular access device|