US3368558A - Two compartment cartridge - Google Patents

Two compartment cartridge Download PDF

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Publication number
US3368558A
US3368558A US391836A US39183664A US3368558A US 3368558 A US3368558 A US 3368558A US 391836 A US391836 A US 391836A US 39183664 A US39183664 A US 39183664A US 3368558 A US3368558 A US 3368558A
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United States
Prior art keywords
needle
washer
compartment
wall
stopper
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Expired - Lifetime
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US391836A
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Stanley J Sarnoff
John W Balenger
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Sarnoff Corp
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Sarnoff Corp
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Priority to US391836A priority Critical patent/US3368558A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A61M5/2466Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287Accessories for bringing the needle into the body; Automatic needle insertion

Definitions

  • ABSTRACT OF THE DISCLOSURE In a cartridge wherein medicament is stored in one compartment thereof and a double pointed needle in another compartment, means are provided to prevent the needle from piercing a wall separating the needle from the medicament compartment prior to full emergence of the opposite end of the needle through a wall separating the needle compartment with the ambient atmosphere.
  • This invention relates to a two compartment cartridge for use in a hypodermic syringe. More specifically, it relates to a two compartment cartridge wherein a hollow needle is stored in one of the compartments and a medication is stored in the other compartment.
  • FIG. 1 is a perspective view of the cartridge in unoperated condition, that is, with the needle in storage position.
  • FIG. 2 is an enlarged cross-sectional view of the cartridge, parts being broken away, in the storage position of the needle.
  • FIG. 3 is a similar view with the front end of the needle projected through the wall of the storage compartment and the needle about to penetrate into the medicament compartment.
  • FIG. 4 is a similar view with the rear end of the needle within the medicament compartment, and
  • FIG. 5 is an enlarged view of a portion of the advancing means.
  • a cartridge casing in the form of a cylinder made of metal, plastic or glass, and here shown as of glass, within which is a rear medicament compartment 12 and a hollow needle front storage compartment 14.
  • the two compartments are separated by a translatable wall 16, preferably of rubber, the medicament compartment being closed off by a piston 18, also preferably of rubber.
  • a medicament 19, as a fluid medicament, is located in the compartment 12.
  • a hollow needle with a bevelled rear end 22 and a bevelled front end 24.
  • the rear end of this needle normally rests in a recess 26 in wall 16 with its bevelled end close to a comparatively thin septum or membrane 28 between the recess 26 and a second registering recess 29.
  • the forward end of the front compartment is closed off by a stopper 30, also preferably of rubber, the stopper being provided with a recess 32 accommodating the forward bevelled end of the needle.
  • the closure 34 at the front end of the stopper is a comparatively thin membrane and it may project slightly be- 3,368,558 Patented Feb. 13, 1968 yond the outer surface of the stopper. The stopper is tightly frictionally held in the casing 10.
  • a description of the blocking device follows: Fixed to and surrounding the outer periphery of the needle, and at a slight distance from the diaphragm is an annular washer 36. Embedded in the face of the wall 16, as by being frictionally held in a recess in the wall, is a washer 38 freely surrounding the needle. This washer has one or more pliable fingers 40 extending toward and engaging the rear face of the washer 36. Any number of such fingers may be employed although three fingers equally spaced circumferen'tially of the washer 38 is preferred. Each finger has a toe portion 42 having a face parallel to the rear face of the washer bearing against the washer 36 and an inclined portion 44 forming a cam end of the finger. The toe portion has a bevelled edge 46 for a purpose which will be disclosed.
  • a metal washer 48 loosely surrounding the needle and serving to center the forward end of the needle to ensure penetration of the stopper 30 at the proper area.
  • the washer it is made with a rear conical surface rather than a plane surface to better act as a camming surface, as will be explained.
  • a cartridge comprising a casing, a piston adjacent one end of the casing, a translatable wall within the casing intermediate the ends of the casing, and a stopper at the other end of the casing, a medicament in a first compartment formed in the casing between the piston and translatable wall, a hollow needle in a second compartment formed in the casing between the intermediate wall and the stopper, and a mechanical drive connection between the needle and translatable wall having a part driven by the Wall and a part fixed to the needle to cause the needle to penetrate the stopper on displacement of the piston, and means engaged by a part of the mechanical connection in its displacement within the casing to uncouple the connection whereby the wall moves relative to the needle and the needle subsequently pierces the wall, the fiuid then being ejected through the needle, said drive connection comprising a washer afiixed to the needle and a pliable finger carried by the translatable Wall engaging the washer, the finger extending angularly in a direction toward the stop

Description

Feb. 13, 1968 5. J. SARNOFF ET AL 3,368,558
TWO COMPARTMENT CARTRIDGE Filed Aug. 21, 1964 r INVENTORS Sfan/ew J. Sarnoff lll John W fialehger BY ATTORNEYS United States Patent ()fiice 3,368,558 TWO CUMPARTMENT CARTRIDGE Stanley J. Sarnofi, 7801 Woodmont Avc., Montgomery County, Md. 20014, and John W. Balenger, Montgomery County, Md.; said Balenger assignor to said Sarnoff Filed Aug. 21, 1964, Ser. No. 391,836 2 Claims. (Cl. 128218) ABSTRACT OF THE DISCLOSURE In a cartridge wherein medicament is stored in one compartment thereof and a double pointed needle in another compartment, means are provided to prevent the needle from piercing a wall separating the needle from the medicament compartment prior to full emergence of the opposite end of the needle through a wall separating the needle compartment with the ambient atmosphere.
This invention relates to a two compartment cartridge for use in a hypodermic syringe. More specifically, it relates to a two compartment cartridge wherein a hollow needle is stored in one of the compartments and a medication is stored in the other compartment.
It is an object of this invention to provide a positive means for ensuring that the needle be advanced from its storage position in the compartment to an operative position with the forward end of the needle exterior of the compartment before the rear end of the needle is brought into communication with the medicament in the rear compartment.
Other objects will become apparent after consideration of the following specification when taken in conjunction with the accompanying drawing in which:
FIG. 1 is a perspective view of the cartridge in unoperated condition, that is, with the needle in storage position.
FIG. 2 is an enlarged cross-sectional view of the cartridge, parts being broken away, in the storage position of the needle.
FIG. 3 is a similar view with the front end of the needle projected through the wall of the storage compartment and the needle about to penetrate into the medicament compartment.
FIG. 4 is a similar view with the rear end of the needle within the medicament compartment, and
FIG. 5 is an enlarged view of a portion of the advancing means.
Referring to the drawing in greater detail, at is indicated a cartridge casing in the form of a cylinder made of metal, plastic or glass, and here shown as of glass, within which is a rear medicament compartment 12 and a hollow needle front storage compartment 14. The two compartments are separated by a translatable wall 16, preferably of rubber, the medicament compartment being closed off by a piston 18, also preferably of rubber. A medicament 19, as a fluid medicament, is located in the compartment 12.
Within the front compartment is a hollow needle with a bevelled rear end 22 and a bevelled front end 24. The rear end of this needle normally rests in a recess 26 in wall 16 with its bevelled end close to a comparatively thin septum or membrane 28 between the recess 26 and a second registering recess 29. The forward end of the front compartment is closed off by a stopper 30, also preferably of rubber, the stopper being provided with a recess 32 accommodating the forward bevelled end of the needle. The closure 34 at the front end of the stopper is a comparatively thin membrane and it may project slightly be- 3,368,558 Patented Feb. 13, 1968 yond the outer surface of the stopper. The stopper is tightly frictionally held in the casing 10.
When pressure is applied to the piston 18, the wall 16 will be advanced due to the transmission of force through the liquid medicament 14. In the absence of control devices such as will be described, the bevelled ends of the needle would penetrate the membranes 28 and 34 in an order detremined by the sharpness of the bevelled ends of the needles, the thickness and density of the membranes, and the quality of the membranes. A further variable exists in that continued contact of the medicament with the rubber septum 28 may cause softening and deterioration of the rubber. Because of all of these variables, even though it may have been intended to have the membrane 34 pierced before the septum 28 was pierced, there was no certainty that this order of piercing would take place.
However, by interposing a releasable blocking device between the translatable wall 16 and needle it is possible to ensure the piercing of the membrane 34 and extrusion of the forward needle end beyond the stopper 30 prior to establishing communication between the medicament containing chamber and the lumen of the needle.
A description of the blocking device follows: Fixed to and surrounding the outer periphery of the needle, and at a slight distance from the diaphragm is an annular washer 36. Embedded in the face of the wall 16, as by being frictionally held in a recess in the wall, is a washer 38 freely surrounding the needle. This washer has one or more pliable fingers 40 extending toward and engaging the rear face of the washer 36. Any number of such fingers may be employed although three fingers equally spaced circumferen'tially of the washer 38 is preferred. Each finger has a toe portion 42 having a face parallel to the rear face of the washer bearing against the washer 36 and an inclined portion 44 forming a cam end of the finger. The toe portion has a bevelled edge 46 for a purpose which will be disclosed.
While not necessary, it is preferred to supply a metal washer 48 loosely surrounding the needle and serving to center the forward end of the needle to ensure penetration of the stopper 30 at the proper area. In a preferred form of the washer it is made with a rear conical surface rather than a plane surface to better act as a camming surface, as will be explained. In operation, when pressure is applied to the piston 18, as by thrust of a plunger rod of a syringe against the piston, the wall 16 is translated through the intermediary of the liquid link 19. Thereupon the toe 42 or the toes 42 thrust on the needle mounted washer 36 and drive the washer and afiixed needle through the membrane 34 of the stopper 30. The needle is thrust through the stopper by reason of the coupling action of the fingers until the cam portion 44 of pliable finger 40 engages the stopper 30 or the washer 48 where the latter is used. Since this end of the finger extends only slightly below the washer 36, washer 36 is now close to washer 48. The free end of each of the fingers, on further downward movement of the wall 16, slides along the rear surface of the washer 48 and radially away from the needle thereby freeing the toe from the washer 36 the cam portion 46 assisting such action. Now that the block between the needle and wall 16 is removed, the wall 16 slides along the length of the needle, causing the needle to pierce the septum 28. Continued movement of the piston, under the influence exerted by pressure on the piston 18 and liquid medicament 19 causes the forward face of the washer 38 to engage and drive the washer 36 into firm engagement with the washer 48, thereby preventing rearward movement of the needle 20. Also, medicament is now ejected from the needle.
Having thus described the invention, what is claimed is:
l. A cartridge comprising a casing, a piston adjacent one end of the casing, a translatable wall within the casing intermediate the ends of the casing, and a stopper at the other end of the casing, a medicament in a first compartment formed in the casing between the piston and translatable wall, a hollow needle in a second compartment formed in the casing between the intermediate wall and the stopper, and a mechanical drive connection between the needle and translatable wall having a part driven by the Wall and a part fixed to the needle to cause the needle to penetrate the stopper on displacement of the piston, and means engaged by a part of the mechanical connection in its displacement within the casing to uncouple the connection whereby the wall moves relative to the needle and the needle subsequently pierces the wall, the fiuid then being ejected through the needle, said drive connection comprising a washer afiixed to the needle and a pliable finger carried by the translatable Wall engaging the washer, the finger extending angularly in a direction toward the stopper and away from the needle, and the means for uncoupling the connection including a second Washer adjacent the stopper, the second washer being engaged by the end of the finger and effecting radial displacement of the end of the finger away from the needle.
2. The structure of claim 1 wherein the rear face of the "washer is conical with the conical apex of the Washer surrounding the needle.
References Cited UNITED STATES PATENTS 1,767,304 6/1930 Morton 128220 2,408,323 9/1946 Lockhart 128220 2,460,039 1/1949 Scherer 128218 RICHARD A. GAUDET, Primary Examiner.
D. L. BAKER, Assistant Examiner.
US391836A 1964-08-21 1964-08-21 Two compartment cartridge Expired - Lifetime US3368558A (en)

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Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3583399A (en) * 1968-09-03 1971-06-08 Astra Chem Ltd Self-aspirating syringe
US3636950A (en) * 1968-11-14 1972-01-25 American Home Prod Disposable cartridge for admixing two components of injectable medicament
US4553962A (en) * 1983-01-17 1985-11-19 Brunet Jean Louis Medical syringe
US4643721A (en) * 1984-11-20 1987-02-17 Poutrait-Morin Multiple compartment ampule for automatic hypodermic syringes
US4747829A (en) * 1987-01-21 1988-05-31 E. R. Squibb & Sons, Inc. Pre-filled syringe
EP0276522A1 (en) * 1986-01-13 1988-08-03 Eldon E. Larson Lubricating device
US4929237A (en) * 1988-11-07 1990-05-29 David Medway Hypodermic needle protection device
US4932944A (en) * 1988-03-09 1990-06-12 The University Of Virginia Alumni Patents Foundation Intravenous port injection and connector system
US4988339A (en) * 1988-12-30 1991-01-29 Vadher Dinesh L Retractable needle/syringe devices for blood collection, catheterization, and medicinal injection procedures
US5102393A (en) * 1989-07-17 1992-04-07 Survival Technology, Inc. Autoinjector converted from intramuscular to subcutaneous mode of injection
EP0598055A1 (en) * 1991-08-06 1994-05-25 Senetek Plc Medicament injector and method
EP0616541A1 (en) * 1992-10-05 1994-09-28 Senetek Plc Medicament injectors and methods
WO1995011712A1 (en) * 1993-10-26 1995-05-04 Eastland Technology Australia Pty. Ltd. Syringe or like parenteral device
US5562635A (en) * 1992-04-21 1996-10-08 Eastland Technology Australia Pty Ltd Parenteral device
WO1997002855A1 (en) * 1995-07-12 1997-01-30 Societe D'etudes Et D'applications Techniques - Sedat Self-protected injection syringe
US5709668A (en) * 1991-01-16 1998-01-20 Senetek Plc Automatic medicament injector employing non-coring needle
US5993418A (en) * 1998-02-24 1999-11-30 Medisys Technologies, Inc. Safety syringe
US6450216B1 (en) * 1998-10-26 2002-09-17 Valois, S.A. Reservoir provided with a device for closing and/or filling and device for dispensing a fluid product comprising same
US6626863B1 (en) 2000-11-22 2003-09-30 Nusaf, L.L.C. Safety syringe
US20050029288A1 (en) * 2001-11-15 2005-02-10 Frederic Heldt Fluid product dispensing device
WO2010100244A1 (en) * 2009-03-06 2010-09-10 Sanofi-Aventis Deutschland Gmbh Seal member for syringe with retractable needle
JP2013542022A (en) * 2010-11-03 2013-11-21 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Medicinal module with a deformable membrane
US20150335827A1 (en) * 2012-12-19 2015-11-26 Novo Nordisk A/S A Needle Device
US20160166765A1 (en) * 2011-10-14 2016-06-16 Amgen Inc. Injector and method of assembly
US20190060569A1 (en) * 2017-08-30 2019-02-28 Pirouette Medical LLC Compact auto-injector
US10850037B2 (en) 2013-03-22 2020-12-01 Amgen Inc. Injector and method of assembly
US11097055B2 (en) 2013-10-24 2021-08-24 Amgen Inc. Injector and method of assembly

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1767304A (en) * 1927-12-30 1930-06-24 Henry S Morton Injection apparatus
US2408323A (en) * 1943-06-10 1946-09-24 Margaret L Lockhart Hypodermic syringe
US2460039A (en) * 1944-04-14 1949-01-25 Scherer Corp R P Hypodermic syringe

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1767304A (en) * 1927-12-30 1930-06-24 Henry S Morton Injection apparatus
US2408323A (en) * 1943-06-10 1946-09-24 Margaret L Lockhart Hypodermic syringe
US2460039A (en) * 1944-04-14 1949-01-25 Scherer Corp R P Hypodermic syringe

Cited By (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3583399A (en) * 1968-09-03 1971-06-08 Astra Chem Ltd Self-aspirating syringe
US3636950A (en) * 1968-11-14 1972-01-25 American Home Prod Disposable cartridge for admixing two components of injectable medicament
US4553962A (en) * 1983-01-17 1985-11-19 Brunet Jean Louis Medical syringe
US4643721A (en) * 1984-11-20 1987-02-17 Poutrait-Morin Multiple compartment ampule for automatic hypodermic syringes
EP0276522A1 (en) * 1986-01-13 1988-08-03 Eldon E. Larson Lubricating device
US4747829A (en) * 1987-01-21 1988-05-31 E. R. Squibb & Sons, Inc. Pre-filled syringe
EP0276160A2 (en) * 1987-01-21 1988-07-27 E.R. Squibb & Sons, Inc. Pre-filled syringe
EP0276160A3 (en) * 1987-01-21 1988-10-05 Squibb & Sons Inc Pre-filled syringe
US4932944A (en) * 1988-03-09 1990-06-12 The University Of Virginia Alumni Patents Foundation Intravenous port injection and connector system
US4929237A (en) * 1988-11-07 1990-05-29 David Medway Hypodermic needle protection device
WO1991018634A1 (en) * 1988-11-07 1991-12-12 David Charles Medway Hypodermic needle protection device
US4988339A (en) * 1988-12-30 1991-01-29 Vadher Dinesh L Retractable needle/syringe devices for blood collection, catheterization, and medicinal injection procedures
US5102393A (en) * 1989-07-17 1992-04-07 Survival Technology, Inc. Autoinjector converted from intramuscular to subcutaneous mode of injection
US5709668A (en) * 1991-01-16 1998-01-20 Senetek Plc Automatic medicament injector employing non-coring needle
EP0598055A1 (en) * 1991-08-06 1994-05-25 Senetek Plc Medicament injector and method
EP0598055A4 (en) * 1991-08-06 1995-05-24 Senetek Plc Medicament injector and method.
US5562635A (en) * 1992-04-21 1996-10-08 Eastland Technology Australia Pty Ltd Parenteral device
EP0616541A1 (en) * 1992-10-05 1994-09-28 Senetek Plc Medicament injectors and methods
EP0616541A4 (en) * 1992-10-05 1995-04-19 Senetek Plc Medicament injectors and methods.
WO1995011712A1 (en) * 1993-10-26 1995-05-04 Eastland Technology Australia Pty. Ltd. Syringe or like parenteral device
US5762633A (en) * 1993-10-26 1998-06-09 Eastland Technology Australia Pty, Ltd. Syringe or like parenteral device
WO1997002855A1 (en) * 1995-07-12 1997-01-30 Societe D'etudes Et D'applications Techniques - Sedat Self-protected injection syringe
US6110147A (en) * 1995-07-12 2000-08-29 Societe D'etudes D'applications Techniques-Sedat Self-protected injection syringe
US6569124B1 (en) 1995-07-12 2003-05-27 Societe D'etudes Et D'applications Techniques-Sedat Self-protected injection syringe
US5993418A (en) * 1998-02-24 1999-11-30 Medisys Technologies, Inc. Safety syringe
US6450216B1 (en) * 1998-10-26 2002-09-17 Valois, S.A. Reservoir provided with a device for closing and/or filling and device for dispensing a fluid product comprising same
US6626863B1 (en) 2000-11-22 2003-09-30 Nusaf, L.L.C. Safety syringe
US20050029288A1 (en) * 2001-11-15 2005-02-10 Frederic Heldt Fluid product dispensing device
US8419706B2 (en) * 2001-11-15 2013-04-16 Aptar France Sas Fluid product dispensing device
WO2010100244A1 (en) * 2009-03-06 2010-09-10 Sanofi-Aventis Deutschland Gmbh Seal member for syringe with retractable needle
JP2012519512A (en) * 2009-03-06 2012-08-30 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Seal member for a syringe with a retractable needle
US8597256B2 (en) 2009-03-06 2013-12-03 Sanofi-Aventis Deutschland Gmbh Seal member
JP2013542022A (en) * 2010-11-03 2013-11-21 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Medicinal module with a deformable membrane
US10537681B2 (en) * 2011-10-14 2020-01-21 Amgen Inc. Injector and method of assembly
US11110225B2 (en) * 2011-10-14 2021-09-07 Amgen Inc. Injector and method of assembly
US20160199578A1 (en) * 2011-10-14 2016-07-14 Amgen Inc. Injector and method of assembly
US20180256821A1 (en) * 2011-10-14 2018-09-13 Amgen Inc. Injector and method of assembly
US11298463B2 (en) 2011-10-14 2022-04-12 Amgen Inc. Method of assembling and filling a drug delivery device
US11273260B2 (en) 2011-10-14 2022-03-15 Amgen Inc. Injector and method of assembly
US11160931B2 (en) 2011-10-14 2021-11-02 Amgen Inc. Method of assembling and filling a drug delivery device
US10314976B2 (en) 2011-10-14 2019-06-11 Amgen Inc. Method of assembling and filling a drug delivery device
AU2020200659B2 (en) * 2011-10-14 2021-10-21 Amgen Inc. Injector and method of assembly
US11129941B2 (en) 2011-10-14 2021-09-28 Amgen Inc. Method of assembling and filling a drug delivery device
US10537682B2 (en) * 2011-10-14 2020-01-21 Amgen Inc. Injector and method of assembly
US20200179609A1 (en) * 2011-10-14 2020-06-11 Amgen Inc. Injector and method of assembly
US20160166765A1 (en) * 2011-10-14 2016-06-16 Amgen Inc. Injector and method of assembly
US11058821B2 (en) * 2011-10-14 2021-07-13 Amgen Inc. Injector and method of assembly
US20150335827A1 (en) * 2012-12-19 2015-11-26 Novo Nordisk A/S A Needle Device
US10850037B2 (en) 2013-03-22 2020-12-01 Amgen Inc. Injector and method of assembly
US11759571B2 (en) 2013-03-22 2023-09-19 Amgen Inc. Injector and method of assembly
US11097055B2 (en) 2013-10-24 2021-08-24 Amgen Inc. Injector and method of assembly
JP2020532379A (en) * 2017-08-30 2020-11-12 ピルエット メディカル エルエルシー Compact automatic syringe
US10449296B2 (en) * 2017-08-30 2019-10-22 Pirouette Medical LLC Compact auto-injector
US20190167905A1 (en) * 2017-08-30 2019-06-06 Pirouette Medical LLC Compact auto-injector
US10265471B2 (en) * 2017-08-30 2019-04-23 Pirouette Medical LLC Compact auto-injector
US20190060569A1 (en) * 2017-08-30 2019-02-28 Pirouette Medical LLC Compact auto-injector

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