US3342181A - Forms of ovules - Google Patents

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US3342181A
US3342181A US376690A US37669064A US3342181A US 3342181 A US3342181 A US 3342181A US 376690 A US376690 A US 376690A US 37669064 A US37669064 A US 37669064A US 3342181 A US3342181 A US 3342181A
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ovule
finger
depression
ovules
shape
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Jacquignon Norbert
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/08—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of suppositories or sticks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms

Definitions

  • the present invention relates to ovules, that is to say pharmaceutical preparations intended to be used by placing in position in the vagina of the patient, and more particularly to the shape of the said ovules, irrespective of the substances of which they are constituted.
  • ovules Up to the present time, ovules have been delivered in full, transversely rounded, more or less longitudinally oval shapes from which their name of ovules is derived. These shapes often render their utilization difficult for the operator and/ or painful for the patient.
  • these lesions are usually situated at the top of the vagina, at the level of the uterine cervex.
  • the ovules which are actually in use are not at all convenient to apply, so that in the majority of cases the patient leaves the ovule in the centre or in the lower third of the vaginal duct, which has the result of depriving the treatment of all or part of its therapeutic value.
  • the invention has for its object to obviate these disadvantages.
  • the invention has therefore for its object an ovule having a shape such as to facilitate placing it in its therapeutic position in the vagina.
  • the invention has also for its object an ovule having a shape which permits it to be easily placed in the therapeutic position by the patient herself.
  • the invention has finally for its object an ovule having a shape which permits it to be easily placed in the therapeutic position, even by the patient herself, even 'when the said therapeutic position is at the top of the vagina, at the level of the uterine cervix.
  • the invention contemplates giving the ovule a general shape comprising a depression which fits more or less completely on the end of a finger of the operator or the patient.
  • This depression enables the ovule to be easily taken from its packing box, to be readily handled, and the finger with the ovule fitted over it is easily and conveniently introduced into the vagina up to the prescribed therapeutic position at which the finger must leave the ovule.
  • the ovule according to the invention is in the form of a glove finger which can easily be guided until it comes into contact with the uterine cervix, by the finger on which it is introduced.
  • the invention has for its further object an ovule, the arrangement of which permits the finger to leave the ovule readily in its therapeutic position.
  • These arrangements of the ovule according to the invention may apply to the exterior shape, which may be more or less flared in order to facilitate the retention of the ovule in and by the vagina, and/ or which may comprise for the same purpose, a head in the form of a cupping lass.
  • These arrangements of the ovule accordinging to the invention may be applied to the outer walls, which may be striated, once more in order to facilitate the retention of the ovule in and by the vagina.
  • ovule according to the invention may be applied to the inner walls, which may be fluted longitudinally in order to facilitate releasing the ovule in its position by the finger, by reducing the surface of contact of the ovule with the finger and permitting air to pass along the finger towards the bottom of the depression of the ovule.
  • These arrangements of the ovule according to the invention may comprise an orifice in the head of the ovule and opening into the bottom of the depression in the ovule, leaving air to pass when the ovule is left in position, and furthermore increasing the rapidity of disintegration of the ovule, as will be explained later.
  • the invention consists of new shapes of ovules and eventually of the new arrangements described and claimed below, it being understood that modifications of the particular applications described below may be effected within the scope of the claims without departing from the invention.
  • FIG. 1 shows a perspective view of an ovule which is shown in longitudinal section in FIG. 2.
  • FIG. 3 gives a perspective view of another ovule in the form of a small bell, which is represented in FIG. 4 in transverse section taken along. the line IV-IV of FIG. 3.
  • FIG. 5 shows an axial cross-section of a further form of an ovule fitting over the finger of the operator or the patient.
  • FIG. 6 represents in axial cross-section a further arrangement of an ovule which fits over the finger of the operator or the patient.
  • FIG. 7 shows a further ovule in the shape of a glove finger which is shown in axial section in FIG. 8.
  • FIGS. 9 and 10 are transverse sections showing certain adaptations of the ovule shown in FIGS. 7 and 8.
  • FIG. 11 is an axial cross-section of a still further form of ovule.
  • the ovules 1 are generally characterized in that they comprise a depression 2 intended to fit over the extremity of a finger, enabling them to be handled, to be directed and deposited easily in the desired positions in the vagina.
  • depressions may have very varied curvatures and parts in relief so as to ensure good coaptation of the finger and an easy Withdrawal of this latter.
  • the external surfaces of the ovules they may be given any shapes which are deemed suitable.
  • FIGS. 1 and 2 represent more particularly a gynecological ovule which is hollowed out in the same way as a sewing thimble, and the internal walls: of the depression 2 are smooth. This form would be more particularly recommended for hard ovules produced by stamping under compression.
  • the ovule 1 has been given the external appearance of a small bell (FIGS. 3 and 4) in which the free edge, slightly flared at 4 facilitates its retention in the vagina.
  • the depression or housing 2 of this ovule may be provided with longitudinal flutes 5 intended to leave a passage for the air so as to facilitate the withdrawal of the finger. This form would be more particularly recommended for soft ovules produced by moulding.
  • the bottom of the depression 2 has a convex portion 6 surrounded by a circular groove 7 serving as a housing to receive the nail 8 of the finger 3.
  • This convex portion may be pierced at 9 so as to permit easy withdrawal of the finger while leaving the ovule in the therapeutic position.
  • the orifice 9 has the further advantage of permitting the rapid passage of vaginal secretions to the interior of the cavity, and by this fact of accelerating the disintegration of the ovule.
  • the ovule 1 is given the shape of a glove finger, the internal cavity 2 of which permits the introduction of the finger in order that this latter, fitting perfectly in the ovule, may guide the latter easily up to the end of the vaginal duct.
  • the ovule may be given any dimensions considered suitable, and the thickness of the head 10 (see FIG. 8) may vary according to the quantity of medicinal products which it is desired to introduce.
  • the ovule In order to facilitate the removal of the finger when the ovule has been put into position, it is preferable in this case that the ovule should be provided with a hole 9 which will permit the passage of air, since otherwise a depression would be produced which might be sufiicient to prevent the finger from being withdrawn from the ovule.
  • FIGS. 9 and 10 are two examples of construction (the finger 3 being shown in chain-dotted lines).
  • the cavity 2 of the ovule is provided, as previously described, with a small circular groove 7 formed in the bottom of the said cavity. This groove is provided so as to receive the nail 8 of the finger 3. A convex portion 11 which comes into contact with the end of the finger permits the ovule to be pushed normally without damaging it.
  • the ovule on the utero-vaginal mucous membrane may be given an external shape in conformity with the treatment considered. It may for example, as already stated, have the shape of a hell with a flared edge, with smooth or striated Walls, and it may also be provided with a head in the form of a cupping-glass, etc.
  • this ovule with a large surface area will be of special value, especially for certain types of ovules, the disintegration of which is generally slow and sometimes causes local irritation.
  • An ovule comprising a one-piece member hollowed out to form a depression contoured to fit over the extremity of the finger of the user during the placing of said ovule in its therapeutic position, said ovule being c0nfigured to a shape similar to that of a sewing thimble including a head portion, internal and external walls, having a free edge, the free edge of said ovule being slightly flared, the external wall of the ovule being striated, the head of the ovule being pierced with at least one orifice opening into said depression, said internal wall of said depression being provided with longitudinal flutings.
  • An ovule comprising a one-piece member hollowed out to form a depression contoured to fit over the extremity of the finger of the user during the placing of the ovule in its therapeutic position, said ovule having the shape of a glove finger and including internal and outer walls having a free edge, said free edge of the ovule being slightly flared, the ovule having the shape of a glove finger, the outer walls of the ovule being striated, the head of the ovule being pierced with at least one orifice opening itno said depression, the internal wall of said depression being provided with longitudinal flutings.
  • An ovule comprising a one-piece member hollowed out to .form a depression contoured to fit over the extremity of the finger of the user during the placing of said ovule in its therapeutic position, said ovule being in the shape of a glove finger, having a closed end portion and internal and outer walls and an edge portion, the edge of the ovule being slightly flared, the outer Walls of said ovule being striated, the internal walls of the depression being provided with longitudinal flutings, said closed end portion of said member having a convex portion and a circular groove surrounding said convex portion adapted to receive the nail of the user.

Description

Sefl. 19, 1967 N. JACQUIGNON FORMS OF OVULES Filed June 22, 1964 FIG 2 FIG. I
United States Patent 3,342,181 FORMS OF OVULES Norbert Jacquignon, Paris, France, assignor to Charles Albert Merminod, Paris, France Filed June 22, 1964, Ser. No. 376,690 Claims priority, application France, June 25, 1963, 939,326, Patent 1,407,659 3 Claims. (Cl. 128-260) The present invention relates to ovules, that is to say pharmaceutical preparations intended to be used by placing in position in the vagina of the patient, and more particularly to the shape of the said ovules, irrespective of the substances of which they are constituted.
Up to the present time, ovules have been delivered in full, transversely rounded, more or less longitudinally oval shapes from which their name of ovules is derived. These shapes often render their utilization difficult for the operator and/ or painful for the patient.
In addition, in the case of gynecological lesions Which justify a treatment by ovules, these lesions are usually situated at the top of the vagina, at the level of the uterine cervex. Now, the ovules which are actually in use are not at all convenient to apply, so that in the majority of cases the patient leaves the ovule in the centre or in the lower third of the vaginal duct, which has the result of depriving the treatment of all or part of its therapeutic value.
The invention has for its object to obviate these disadvantages.
The invention has therefore for its object an ovule having a shape such as to facilitate placing it in its therapeutic position in the vagina.
The invention has also for its object an ovule having a shape which permits it to be easily placed in the therapeutic position by the patient herself.
The invention has finally for its object an ovule having a shape which permits it to be easily placed in the therapeutic position, even by the patient herself, even 'when the said therapeutic position is at the top of the vagina, at the level of the uterine cervix.
In its widest aspect, the invention contemplates giving the ovule a general shape comprising a depression which fits more or less completely on the end of a finger of the operator or the patient.
This depression enables the ovule to be easily taken from its packing box, to be readily handled, and the finger with the ovule fitted over it is easily and conveniently introduced into the vagina up to the prescribed therapeutic position at which the finger must leave the ovule.
In the case of gynecological lesions, the ovule according to the invention is in the form of a glove finger which can easily be guided until it comes into contact with the uterine cervix, by the finger on which it is introduced.
The invention has for its further object an ovule, the arrangement of which permits the finger to leave the ovule readily in its therapeutic position.
These arrangements of the ovule according to the invention may apply to the exterior shape, which may be more or less flared in order to facilitate the retention of the ovule in and by the vagina, and/ or which may comprise for the same purpose, a head in the form of a cupping lass. g These arrangements of the ovule acording to the invention may be applied to the outer walls, which may be striated, once more in order to facilitate the retention of the ovule in and by the vagina.
These arrangements of the ovule according to the invention may be applied to the inner walls, which may be fluted longitudinally in order to facilitate releasing the ovule in its position by the finger, by reducing the surface of contact of the ovule with the finger and permitting air to pass along the finger towards the bottom of the depression of the ovule.
These arrangements of the ovule according to the invention may comprise an orifice in the head of the ovule and opening into the bottom of the depression in the ovule, leaving air to pass when the ovule is left in position, and furthermore increasing the rapidity of disintegration of the ovule, as will be explained later.
In view of the above-mentioned objects, and still further objects, the invention consists of new shapes of ovules and eventually of the new arrangements described and claimed below, it being understood that modifications of the particular applications described below may be effected within the scope of the claims without departing from the invention.
Other objects and advantages of the invention will be brought out in the description which follows below, considergd with reference to the accompanying drawings, in whic FIG. 1 shows a perspective view of an ovule which is shown in longitudinal section in FIG. 2.
FIG. 3 gives a perspective view of another ovule in the form of a small bell, which is represented in FIG. 4 in transverse section taken along. the line IV-IV of FIG. 3.
FIG. 5 shows an axial cross-section of a further form of an ovule fitting over the finger of the operator or the patient.
FIG. 6 represents in axial cross-section a further arrangement of an ovule which fits over the finger of the operator or the patient.
FIG. 7 shows a further ovule in the shape of a glove finger which is shown in axial section in FIG. 8.
FIGS. 9 and 10 are transverse sections showing certain adaptations of the ovule shown in FIGS. 7 and 8.
FIG. 11 is an axial cross-section of a still further form of ovule.
Referring now to FIG. 1, which is a perspective view, and to FIG. 2 which is a longitudinal section, the ovules 1 according to the invention are generally characterized in that they comprise a depression 2 intended to fit over the extremity of a finger, enabling them to be handled, to be directed and deposited easily in the desired positions in the vagina.
These depressions may have very varied curvatures and parts in relief so as to ensure good coaptation of the finger and an easy Withdrawal of this latter. As regards the external surfaces of the ovules, they may be given any shapes which are deemed suitable.
FIGS. 1 and 2 represent more particularly a gynecological ovule which is hollowed out in the same way as a sewing thimble, and the internal walls: of the depression 2 are smooth. This form would be more particularly recommended for hard ovules produced by stamping under compression.
In accordance with a further application of the inven: tion, the ovule 1 has been given the external appearance of a small bell (FIGS. 3 and 4) in which the free edge, slightly flared at 4 facilitates its retention in the vagina. The depression or housing 2 of this ovule may be provided with longitudinal flutes 5 intended to leave a passage for the air so as to facilitate the withdrawal of the finger. This form would be more particularly recommended for soft ovules produced by moulding.
In accordance with still another application of the invention shown in FIGS. 5 and 6, the bottom of the depression 2 has a convex portion 6 surrounded by a circular groove 7 serving as a housing to receive the nail 8 of the finger 3. This convex portion may be pierced at 9 so as to permit easy withdrawal of the finger while leaving the ovule in the therapeutic position. In addition, the orifice 9 has the further advantage of permitting the rapid passage of vaginal secretions to the interior of the cavity, and by this fact of accelerating the disintegration of the ovule.
In accordance with a further application of the invention shown in FIGS. 7 and 8, the ovule 1 is given the shape of a glove finger, the internal cavity 2 of which permits the introduction of the finger in order that this latter, fitting perfectly in the ovule, may guide the latter easily up to the end of the vaginal duct.
The ovule may be given any dimensions considered suitable, and the thickness of the head 10 (see FIG. 8) may vary according to the quantity of medicinal products which it is desired to introduce.
In order to facilitate the removal of the finger when the ovule has been put into position, it is preferable in this case that the ovule should be provided with a hole 9 which will permit the passage of air, since otherwise a depression would be produced which might be sufiicient to prevent the finger from being withdrawn from the ovule.
The entry of air could also be obtained, as already stated, by means of longitudinal flutings (see FIGS. 9 and 10) formed in the face of the cavity 2 in order that the finger is only in contact with portions of this face, of which the FIGS. 9 and 10 are two examples of construction (the finger 3 being shown in chain-dotted lines).
In accordance with still a further application of the invention shown in FIG. 11, the cavity 2 of the ovule is provided, as previously described, with a small circular groove 7 formed in the bottom of the said cavity. This groove is provided so as to receive the nail 8 of the finger 3. A convex portion 11 which comes into contact with the end of the finger permits the ovule to be pushed normally without damaging it.
In order to facilitate the retention of the ovule on the utero-vaginal mucous membrane, it may be given an external shape in conformity with the treatment considered. It may for example, as already stated, have the shape of a hell with a flared edge, with smooth or striated Walls, and it may also be provided with a head in the form of a cupping-glass, etc.
As the speed of disintegration of the ovule is a function of its surface, this ovule with a large surface area will be of special value, especially for certain types of ovules, the disintegration of which is generally slow and sometimes causes local irritation.
It is obvious that the ovules described and shown have only been given by way of examples and without any limitation, and that all modifications of form and detail may be made to them without thereby departing from the scope of the invention. As will be readily understood by those skilled in the art, such modifications and other combinations of the various arrangements described above, are considered as falling within the scope of the invention as defined in the appended claims.
What I claim is:
1. An ovule comprising a one-piece member hollowed out to form a depression contoured to fit over the extremity of the finger of the user during the placing of said ovule in its therapeutic position, said ovule being c0nfigured to a shape similar to that of a sewing thimble including a head portion, internal and external walls, having a free edge, the free edge of said ovule being slightly flared, the external wall of the ovule being striated, the head of the ovule being pierced with at least one orifice opening into said depression, said internal wall of said depression being provided with longitudinal flutings.
2. An ovule comprising a one-piece member hollowed out to form a depression contoured to fit over the extremity of the finger of the user during the placing of the ovule in its therapeutic position, said ovule having the shape of a glove finger and including internal and outer walls having a free edge, said free edge of the ovule being slightly flared, the ovule having the shape of a glove finger, the outer walls of the ovule being striated, the head of the ovule being pierced with at least one orifice opening itno said depression, the internal wall of said depression being provided with longitudinal flutings.
3. An ovule comprising a one-piece member hollowed out to .form a depression contoured to fit over the extremity of the finger of the user during the placing of said ovule in its therapeutic position, said ovule being in the shape of a glove finger, having a closed end portion and internal and outer walls and an edge portion, the edge of the ovule being slightly flared, the outer Walls of said ovule being striated, the internal walls of the depression being provided with longitudinal flutings, said closed end portion of said member having a convex portion and a circular groove surrounding said convex portion adapted to receive the nail of the user.
References Cited UNITED STATES PATENTS Re. 21,943 11/1941 Munro 128271 3,054,403 9/1962 Baker 128-27O 3,170,464 2/1965 Forti et al 128--271 FOREIGN PATENTS 479 1/ 1888 Great Britain.
ADELE M. EAGER, Primary Examiner.

Claims (1)

1. AN OVULE COMPRISING A ONE-PIECE MEMBER HOLLOWED OUT TO FORM A DEPRESSION CONTOURED TO FIT OVER THE EXTREMITY OF THE FINGER OF THE USER DURING THE PLACING OF SAID OVULE IN ITS THERAPEUTIC POSITION, SAID OVULE BEING CONFIGURED TO A SHAPE SIMILAR TO THAT OF A SEWING THIMBLE INCLUDING A HEAD PORTION, INTERNAL AND EXTERNAL WALLS, HAVING A FREE EDGE, THE FREE EDGE OF SAID OVULE BEING SLIGHTLY FLARED, THE EXTERNAL WALL OF THE OVULE BEING STRIATED, THE HEAD OF THE OVULE BEING PIERCED WITH AT LEAST ONE ORIFICE OPENING INTO SAID DEPRESSION, SAID INTERNAL WALL OF SAID DEPRESSION BEING PROVIDED WITH LONGITUDINAL FLUTINGS.
US376690A 1963-06-25 1964-06-22 Forms of ovules Expired - Lifetime US3342181A (en)

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FR939326A FR1407659A (en) 1963-06-25 1963-06-25 Perfected egg shapes

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BE (1) BE649660A (en)
CH (1) CH429020A (en)
DE (1) DE1931257U (en)
DK (1) DK115947B (en)
ES (1) ES111317Y (en)
FR (1) FR1407659A (en)
NL (1) NL6407188A (en)
OA (1) OA00085A (en)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3443563A (en) * 1966-08-29 1969-05-13 Atsumi Ishihama Vaginal suppository
US3496938A (en) * 1966-08-18 1970-02-24 Eisai Co Ltd Contraceptive membranes and preparation thereof
US3763861A (en) * 1968-12-16 1973-10-09 E Forti Contraceptive means
US3766008A (en) * 1970-03-31 1973-10-16 L Macomber Equine semen extender
US3786807A (en) * 1972-02-29 1974-01-22 D Dubin Disposable diaphragm and insertion-removal unit therefor
US3881485A (en) * 1973-07-16 1975-05-06 Jr Hal M Davis Rectal appliance
US3886940A (en) * 1970-07-10 1975-06-03 Squibb & Sons Inc Capsule
US4037601A (en) * 1976-04-30 1977-07-26 Denkinger Marian C Process for preparing sterilized feminine hygiene articles of non-woven and woven textures
US4252787A (en) * 1976-12-27 1981-02-24 Cambridge Research And Development Group Anti-fertility composition and method
US4310510A (en) * 1976-12-27 1982-01-12 Sherman Kenneth N Self administrable anti-fertility composition
US20040097866A1 (en) * 2002-11-15 2004-05-20 Kyoto Kogyo Co., Ltd. Anal prolapse prevention aid
USD740424S1 (en) * 2012-07-26 2015-10-06 Paragon 28, Inc. Metatarsal phalangeal length restoration disc
USD757925S1 (en) * 2014-05-20 2016-05-31 3M Innovative Properties Company Earplug tip
USD759802S1 (en) * 2014-05-20 2016-06-21 3M Innovative Properties Company Earplug tip
USD1001994S1 (en) 2021-03-11 2023-10-17 Leo Corona Condom

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX164212B (en) * 1984-11-15 1992-07-20 Wolfgang Knogler IMPROVED CONTRACEPTIVE APPARATUS WITH CYLINDRICAL SUPPORTING BODY

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE21943E (en) * 1941-11-11 Medical device
US3054403A (en) * 1960-04-22 1962-09-18 Glennie G Baker Vaginal sanitation apparatus
US3170464A (en) * 1961-01-26 1965-02-23 Forti Emilio Contraceptive means

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE21943E (en) * 1941-11-11 Medical device
US3054403A (en) * 1960-04-22 1962-09-18 Glennie G Baker Vaginal sanitation apparatus
US3170464A (en) * 1961-01-26 1965-02-23 Forti Emilio Contraceptive means

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496938A (en) * 1966-08-18 1970-02-24 Eisai Co Ltd Contraceptive membranes and preparation thereof
US3443563A (en) * 1966-08-29 1969-05-13 Atsumi Ishihama Vaginal suppository
US3763861A (en) * 1968-12-16 1973-10-09 E Forti Contraceptive means
US3766008A (en) * 1970-03-31 1973-10-16 L Macomber Equine semen extender
US3886940A (en) * 1970-07-10 1975-06-03 Squibb & Sons Inc Capsule
US3786807A (en) * 1972-02-29 1974-01-22 D Dubin Disposable diaphragm and insertion-removal unit therefor
US3881485A (en) * 1973-07-16 1975-05-06 Jr Hal M Davis Rectal appliance
US4037601A (en) * 1976-04-30 1977-07-26 Denkinger Marian C Process for preparing sterilized feminine hygiene articles of non-woven and woven textures
US4252787A (en) * 1976-12-27 1981-02-24 Cambridge Research And Development Group Anti-fertility composition and method
US4310510A (en) * 1976-12-27 1982-01-12 Sherman Kenneth N Self administrable anti-fertility composition
US20040097866A1 (en) * 2002-11-15 2004-05-20 Kyoto Kogyo Co., Ltd. Anal prolapse prevention aid
USD740424S1 (en) * 2012-07-26 2015-10-06 Paragon 28, Inc. Metatarsal phalangeal length restoration disc
USD757925S1 (en) * 2014-05-20 2016-05-31 3M Innovative Properties Company Earplug tip
USD759802S1 (en) * 2014-05-20 2016-06-21 3M Innovative Properties Company Earplug tip
USD1001994S1 (en) 2021-03-11 2023-10-17 Leo Corona Condom

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AT255653B (en) 1967-07-10
CH429020A (en) 1967-01-31
DK115947B (en) 1969-11-24
ES111317U (en) 1967-12-16
NL6407188A (en) 1964-12-28
DE1931257U (en) 1966-01-20
BE649660A (en) 1964-10-16
OA00085A (en) 1966-01-15
ES111317Y (en) 1968-05-01
FR1407659A (en) 1965-08-06

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