US3225763A - Medicinal injector - Google Patents
Medicinal injector Download PDFInfo
- Publication number
- US3225763A US3225763A US203195A US20319562A US3225763A US 3225763 A US3225763 A US 3225763A US 203195 A US203195 A US 203195A US 20319562 A US20319562 A US 20319562A US 3225763 A US3225763 A US 3225763A
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- Prior art keywords
- nozzle
- flange
- bead
- cover
- groove
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Definitions
- a mainobject of the invention resides in the provision of a throw-away medicinal applicator or injector having a smooth, flexibly rigid, non-metallic tapering and perforated nozzle as for introduction into the anal cavity, said applicator being adapted vto'have hemorrhoidal or other medication contents in a squeezable body for ejection through said nozzle.
- Afurther object of-the invention resides in the provisionof an injector as described wherein the nozzle is provided with an insertion stop orbase portion, the latter further serving to removably engage a nozzle sealing cap applied at the filling plant after the injector body is charged with medication contents.
- a further object of the invention resides in the provision of a medicinal injector formed of a suitable plastic as a polyolefin, including polyethylene and polypropylene, and adapted to be sealed at the filling plant by both a nozzle sealing cap and a bottom wall.
- a further object of the invention resides in the provision of an injector provided with a tapering and hollow nozzle insertable member having end and side perforations for radial and axial distribution of injector contents.
- a further object of the invention resides in the provi sion of a medicinal injector which is sanitary, efficient in operation, discardable after a single use, easy to operate safe in application and economical in cost.
- FIGURE 1 is a view in perspective of a filled and sealed medicinal injector provided with a nozzle sealing
- FIG. 2 is a compound view of the structure of FIG. 1 showing the sealing cap removed from the nozzle of the injector and also showing the body partly cut-away and containing medicaments;
- FIG. 3 is an enlarged and sectional view of FIG. 2 across the plane 33 thereof;
- FIGURE 4 is an enlarged sectional view of FIG. 1 across the plane 44 thereof;
- FIGURE 5 is an enlarged view in perspective of a side edge of the nozzle member per se;
- FIGURE 6 is a sectional view of FIG. 5 across the plane 66 thereof;
- FIGURE 7 is an enlarged sectional view of FIG. 6 across the plane 77 thereof.
- FIGURE 8 is an enlarged sectional view of FIG. 6 across the plane 88 thereof.
- the injector is molded from a suitable plastic such as polyolefin (polyethylene or polypropylene) and is provided with a 'squeezable chambered body generally indicated by numeral 20.
- Body 20 as shown has side wall 21 elliptical in cross-section, said body being adapted to be filled with a medicament 22 ejectable through a nozzle generally indicated by numeral 23.
- a nozzle seal ing cap or cover generally indicated by numeral 24 is applied to nozzle 23 at the filling plant before body 20 is filled from the open bottom, and thereafter a body bottom flexible wall 25 is suitably applied at the filling plant as by heat sealing, said bottom preferably being of the same gauge as side wall 21.
- Nozzle23 is a hollow chamber having a continuous conically shaped side wall 26 and which is of thicker gauge than the squeezable body side wall 21 so as to be relatively rigid.
- Nozzle side wall 26 is provided with an outwardly directed and downwardly inclined flange 27, the outer perimeter thereof following the elliptical perimeter of body side wall 21.
- the flange 27 is of thicker gauge than the body side wall 21 and is connected thereto at the outer perimeter as indicated at numeral 28.
- Nozzle 23 has an upper end wall 29 formed by a inwardly inclined inner side offset providing a central aperture 30. The latter cooperates with radial apertures 31 in the nozzle side wall 26 in spaced banks foroverall distribution of medicament 22.upon squeezing of the body wall 21, the nozzle flange 27 serving as a rigid frame and limitation to the squeezability of said wall 21.
- Flange 27 serves as a stop for insertion of nozzle 23 into the anal or other body cavity and also serves as the base for removable engagement of the sealing cap 24 for nozzle 23.
- Sealing cap 24 is hollow and has a conically shaped relatively rigid side wall 32 terminating in a top wall 33 and a base flange 34, all being formed of thicker gauge so as to be relatively rigid.
- Thewalls and flange of cap 24 follow the shape and are adapted to overlie and seal escape of the injector contents from openings in the nozzle parts.
- cap flange 34 overlies and abuts nozzle flange 27, the latter having an intermediate and peripheral groove 35 for engagement with a depending peripheral bead.36 from cap flange.34.
- cap flange 34 is provided with a peripheral skirt 37 having and engaging in a recess 38 at the upper edge of the inner side therounded peripheral edge 39 of flange 27 as seen in FIG. 4.
- Each bank of nozzle peripheral perforations 31 as shown is radially disposed and is formed in spaced grooves 40 along outer surface elements and intermediate the height of nozzle side wall 26, the side walls 40a of said grooves being tapered as seen in FIG. 5.
- Opposite and corresponding grooves 41 having straight side walls 41a run along the inner surface elements.
- Spaced banks of perforations 31 have separators 31a formed intermediate the common base wall of the outer and inner grooves and each of the perforations 31 at the lower banks presents smaller width openings for differential distribution and when forcing the medicament out under pressure at the nozzle contacting areas with the anal walls (see FIGS. 5, 7 and 8).
- opening 30 at the outer end of nozzle 23 is also sized for controlling distribution relatively. It is understood, however, that other types of openings or perforations are feasible and with various dispositions on wall 26.
- sealing cap 24 is provided with a pair of cars 42 at opposite ends of the long axis of flange 34 for handling and removal purposes.
- the applicator of the invention is intended to be used for single injections and then thrown away. Moreover, in use the user is provided with a sealed charge of medicament and upon removal of cap 24 nozzle 23 is introduced into the anal cavity and squeezed for broad distribution along the nozzle surfaces.
- the nozzle itself although relatively rigid is somewhat flexible and is formed of sterile material such as polypropylene. No tissue damage can be done.
- flange 27 serves as a stop for nozzle insertion and as a relatively rigid frame about which body walls 21 and 25 are squeezed for injection of the medicament through the openings 30 and 31 of the nozzle.
- a medical injector composed of plastic and comprising, a chambered body having compressible side walls, a rigid hollow nozzle integral with the body and having a thicker wall than the side walls of the body, the nozzle being provided at one end with an outwardly-extending, relatively rigid peripheral flange located between the base portion of the nozzle and the upper end of the body, the nozzle being tapered from said flange to its forward end, the nozzle having an outlet opening in said forward end, a plurality of longitudinal grooves in the side wall of the nozzle, at least some of said grooves being provided in their bottoms with a row of elongated outlet slots, which slots decrease in size from the outer part of the nozzle in a direction toward the flange, said nozzle having a sealing cover, the flange on the nozzle terminating in a rounded peripheral edge and having an upward 1y facing angular groove located inwardly of said rounded edge, the sealing cover having a base flange adapted to superpose the nozzle flange, said base f
- a medicinal injector composed of plastic material walls and containing injectable material, a nozzle formed integrally with the side Walls, said nozzle having a tapering, perforated tip, the nozzle having a plurality of spacedapart grooves formed in its outer surface, the grooves defining depressed channels between them, each channel being provided with a plurality of spaced-apart longitudinally-extending slots, said slots differing in width, with the widest slot being located adjacent to the tip of the nozzle, the nozzle being provided at its base with an outwardly-extending flange, said flange having an upwardly-directed groove encircling the base of the nozzle, said flange including a rounded bead disposed around the outside of the groove, a sealing cover for placement over the nozzle, said cover being provided at its bottom with a flange, said flange having an internal downwardly-directed bead and having an annular groove encircling the said bead, the bead Within the cover flange entering the upwardly-facing groove
Description
1366- 1965 N. s. WATERMAN MEDICINAL INJECTOR 2 Sheets-Sheet 1 Filed June 18, 1962 INVENTOR. NEIL S WATERMAN N. 5. WATERMAN MEDICINAL INJECTOR Dec. 28, 1965 2 Sheets-Sheet 2 Filed June 18, 1962 NEIL 6. WATER/441v INVENTOR.
BY a
United States Patent ()flice,
3 ,225 ,763 Patented Dec. 28, 1965 3,225,763 MEDICINAL INJECTOR Neil S. Waterman, Stamford, Conn., assignor, by mesne assignments, to Chesebrough-Ponds, Inc., New York,
N.Y., a corporation of New York Filed June :18, 1962, Ser. No. 203,195
3 Claims. (Cl. 128-232) of the .device and squeezing the body member of the device.
A mainobject of the invention resides in the provision of a throw-away medicinal applicator or injector having a smooth, flexibly rigid, non-metallic tapering and perforated nozzle as for introduction into the anal cavity, said applicator being adapted vto'have hemorrhoidal or other medication contents in a squeezable body for ejection through said nozzle.
Afurther object of-the invention resides in the provisionof an injector as described wherein the nozzle is provided with an insertion stop orbase portion, the latter further serving to removably engage a nozzle sealing cap applied at the filling plant after the injector body is charged with medication contents.
A further object of the invention resides in the provision of a medicinal injector formed of a suitable plastic as a polyolefin, including polyethylene and polypropylene, and adapted to be sealed at the filling plant by both a nozzle sealing cap and a bottom wall.
A further object of the invention resides in the provision of an injector provided with a tapering and hollow nozzle insertable member having end and side perforations for radial and axial distribution of injector contents.
A further object of the invention resides in the provi sion of a medicinal injector which is sanitary, efficient in operation, discardable after a single use, easy to operate safe in application and economical in cost.
These .objects and other incidental ends and advantages of the invention will hereinafter appear in the progress of the disclosure and as pointed out in the appended claims.
Accompanying this specification are drawings showing a preferred form of the invention wherein:
FIGURE 1 is a view in perspective of a filled and sealed medicinal injector provided with a nozzle sealing FIG. 2 is a compound view of the structure of FIG. 1 showing the sealing cap removed from the nozzle of the injector and also showing the body partly cut-away and containing medicaments;
FIG. 3 is an enlarged and sectional view of FIG. 2 across the plane 33 thereof;
FIGURE 4 is an enlarged sectional view of FIG. 1 across the plane 44 thereof;
FIGURE 5 is an enlarged view in perspective of a side edge of the nozzle member per se;
FIGURE 6 is a sectional view of FIG. 5 across the plane 66 thereof;
FIGURE 7 is an enlarged sectional view of FIG. 6 across the plane 77 thereof; and
FIGURE 8 is an enlarged sectional view of FIG. 6 across the plane 88 thereof.
In accordance with the invention and the preferred form shown, the injector is molded from a suitable plastic such as polyolefin (polyethylene or polypropylene) and is provided with a 'squeezable chambered body generally indicated by numeral 20. Body 20 as shown has side wall 21 elliptical in cross-section, said body being adapted to be filled with a medicament 22 ejectable through a nozzle generally indicated by numeral 23. A nozzle seal ing cap or cover generally indicated by numeral 24 is applied to nozzle 23 at the filling plant before body 20 is filled from the open bottom, and thereafter a body bottom flexible wall 25 is suitably applied at the filling plant as by heat sealing, said bottom preferably being of the same gauge as side wall 21.
, Nozzle23 is a hollow chamber having a continuous conically shaped side wall 26 and which is of thicker gauge than the squeezable body side wall 21 so as to be relatively rigid. Nozzle side wall 26 is provided with an outwardly directed and downwardly inclined flange 27, the outer perimeter thereof following the elliptical perimeter of body side wall 21. The flange 27 is of thicker gauge than the body side wall 21 and is connected thereto at the outer perimeter as indicated at numeral 28.
Sealing cap 24 is hollow and has a conically shaped relatively rigid side wall 32 terminating in a top wall 33 and a base flange 34, all being formed of thicker gauge so as to be relatively rigid. Thewalls and flange of cap 24 follow the shape and are adapted to overlie and seal escape of the injector contents from openings in the nozzle parts. As best seen'in FIG. 4, cap flange 34 overlies and abuts nozzle flange 27, the latter having an intermediate and peripheral groove 35 for engagement with a depending peripheral bead.36 from cap flange.34. As shown, cap flange 34 is provided with a peripheral skirt 37 having and engaging in a recess 38 at the upper edge of the inner side therounded peripheral edge 39 of flange 27 as seen in FIG. 4. Thus, a seal-tight and disengageable joint structure is effected between the applicator and the sealing cap parts.
Each bank of nozzle peripheral perforations 31 as shown is radially disposed and is formed in spaced grooves 40 along outer surface elements and intermediate the height of nozzle side wall 26, the side walls 40a of said grooves being tapered as seen in FIG. 5. Opposite and corresponding grooves 41 having straight side walls 41a run along the inner surface elements. Spaced banks of perforations 31 have separators 31a formed intermediate the common base wall of the outer and inner grooves and each of the perforations 31 at the lower banks presents smaller width openings for differential distribution and when forcing the medicament out under pressure at the nozzle contacting areas with the anal walls (see FIGS. 5, 7 and 8). Further, it is to be noted that opening 30 at the outer end of nozzle 23 is also sized for controlling distribution relatively. It is understood, however, that other types of openings or perforations are feasible and with various dispositions on wall 26.
It is to be noted that sealing cap 24 is provided with a pair of cars 42 at opposite ends of the long axis of flange 34 for handling and removal purposes.
The applicator of the invention is intended to be used for single injections and then thrown away. Moreover, in use the user is provided with a sealed charge of medicament and upon removal of cap 24 nozzle 23 is introduced into the anal cavity and squeezed for broad distribution along the nozzle surfaces. The nozzle itself although relatively rigid is somewhat flexible and is formed of sterile material such as polypropylene. No tissue damage can be done. In addition, flange 27 serves as a stop for nozzle insertion and as a relatively rigid frame about which body walls 21 and 25 are squeezed for injection of the medicament through the openings 30 and 31 of the nozzle.
It is understood that minor changes and variations in the size, shape, integration, manner of molding, thickness and material of parts may all be resorted to without departing from the spirit of the invention and the scope of the appended claims.
I claim:
1. A medical injector composed of plastic and comprising, a chambered body having compressible side walls, a rigid hollow nozzle integral with the body and having a thicker wall than the side walls of the body, the nozzle being provided at one end with an outwardly-extending, relatively rigid peripheral flange located between the base portion of the nozzle and the upper end of the body, the nozzle being tapered from said flange to its forward end, the nozzle having an outlet opening in said forward end, a plurality of longitudinal grooves in the side wall of the nozzle, at least some of said grooves being provided in their bottoms with a row of elongated outlet slots, which slots decrease in size from the outer part of the nozzle in a direction toward the flange, said nozzle having a sealing cover, the flange on the nozzle terminating in a rounded peripheral edge and having an upward 1y facing angular groove located inwardly of said rounded edge, the sealing cover having a base flange adapted to superpose the nozzle flange, said base flange having an annular downwardly-extending bead entering the groove in the nozzle flange when the cover is fitted over the nozzle, the base flange having an annular recess located outside of the bead and adapted to fit around and interlock with the rounded peripheral edge of the nozzle flange when the cover is placed over the nozzle and the bead is entered into the groove.
2. A medicinal injector as provided for in claim 1, wherein the rounded peripheral edge of the nozzle flange starts at the outer edge of the groove in the nozzle flange the flange on the cover is provided with a pair of separate radially-projecting, diametrically-opposite ears for manual engagement to separate the cover from the nozzle by an upward prying action.
3. A medicinal injector composed of plastic material walls and containing injectable material, a nozzle formed integrally with the side Walls, said nozzle having a tapering, perforated tip, the nozzle having a plurality of spacedapart grooves formed in its outer surface, the grooves defining depressed channels between them, each channel being provided with a plurality of spaced-apart longitudinally-extending slots, said slots differing in width, with the widest slot being located adjacent to the tip of the nozzle, the nozzle being provided at its base with an outwardly-extending flange, said flange having an upwardly-directed groove encircling the base of the nozzle, said flange including a rounded bead disposed around the outside of the groove, a sealing cover for placement over the nozzle, said cover being provided at its bottom with a flange, said flange having an internal downwardly-directed bead and having an annular groove encircling the said bead, the bead Within the cover flange entering the upwardly-facing groove in the base of the cap while the groove in the cover flange interlocks with the bead on the base of the nozzle when the sealing cover is fitted over the nozzle.
References Cited by the Examiner 1 UNITED STATES PATENTS 1,971,096 8/1934 De Laney 128-232 2,139,653 12/1938 Belfrage 128-251 2,620,938 12/1952 Jesnig 215-41 2,664,088 12/1953 Hoch 128-261 2,690,181 9/1954 Boyer 128-232 2,771,071 11/1956 Mann 128-232 2,778,525 1/1957 Lermer 220- 2,831,600 4/1958 Powers 220-60 2,848,997 8/1958 Miskel et a1 128-232 2,869,545 1/ 1959 Forsyth 128-232 2,987,223 6/1961 Armour 128-261 2,990,563 7/1961 Davidson 128-260 3,109,427 11/1963 Davidson 128-261 FOREIGN PATENTS 1,179,779 12/1958 France.
RICHARD A. GAUDET, Primary Examiner.
RICHARD J. HOFFMAN, JORDAN FRANKLIN,
Examiners.
Claims (1)
1. A MEDICAL INJECTOR COMPOSED OF PLASTIC AND COMPRISING, A CHAMBERED BODY HAVING COMPRESSIBLE SIDE WALLS, A RIGID HOLLOW NOZZLE INTEGRAL WITH THE BODY AND HAVING A THICKER WALL THAN THE SIDE WALLS OF THE BODY, THE NOZZLE BEING PROVIDED AT ONE END WITH AN OUTWARDLY-EXTENDING, RELATIVELY RIGID PERIPHERAL FLANGE LOCATED BETWEEN THE BASE PORTION OF THE NOZZLE AND THE UPPER END OF THE BODY, THE NOZZLE BEING TAPERED FROM SAID FLANGE TO ITS FORWARD END, THE NOZZLE HAVING AN OUTLET OPENING IN SAID FORWARD END, A PLURALITY OF LONGITUDINAL GROOVES IN THE SIDE WALL OF THE NOZZLE, AT LEAST SOME OF SAID GROOVES BEING PROVIDED IN THEIR BOTTOMS WITH A ROW OF ELONGATED OUTLET SLOTS, WHICH SLOTS DECREASE IN SIZE FROM THE OUTER PART OF THE NOZZLE IN A DIRECTION TOWARD THE FLANGE, SAID NOZZLE HAVING A SEALING COVER, THE FLANGE ON THE NOZZLE TERMINATING IN A ROUNDED PERIPHERAL EDGE AND HAVING AN UPWARDLY FACING ANGULAR GROOVE LOCATED INWARDLY OF SAID ROUNDED EDGE, THE SEALING COVER HAVING A BASE FLANGE ADAPTED TO SUPERPOSE THE NOZZLE FLANGE, SAID BASE FLANGE HAVING AN ANNULAR DOWNWARDLY-EXTENDING BEAD ENTERING THE GROOVE IN THE NOZZLE FLANGE WHEN THE COVER IS FITTED OVER THE NOZZLE, THE BASE FLANGE HAVING AN ANNULAR RECESS LOCATED OUTSIDE OF THE BEAD AND ADAPTED TO FIT AROUND AND INTERLOCK WITH THE ROUNDED PERIPHERAL EDGE OF THE NOZZLE FLANGE WHEN THE COVER IS PLACED OVER THE NOZZLE AND THE BEAD IS ENTERED INTO THE GROOVE.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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US203195A US3225763A (en) | 1962-06-18 | 1962-06-18 | Medicinal injector |
Applications Claiming Priority (1)
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US203195A US3225763A (en) | 1962-06-18 | 1962-06-18 | Medicinal injector |
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US3225763A true US3225763A (en) | 1965-12-28 |
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US203195A Expired - Lifetime US3225763A (en) | 1962-06-18 | 1962-06-18 | Medicinal injector |
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Cited By (53)
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US3838681A (en) * | 1972-12-29 | 1974-10-01 | J Dalton | Device for collection of cells from the vagina |
US4453935A (en) * | 1982-04-16 | 1984-06-12 | Chester Labs, Inc. | Disposable container-applicator with leak-proof cover |
DE3406829A1 (en) * | 1983-03-25 | 1984-09-27 | Neopac AG, Oberdiessbach | Device for the application of a liquid to pasty product in body orifices, and a method of producing and operating the same |
EP0139855A1 (en) * | 1983-07-08 | 1985-05-08 | PLANTORGAN WERK Heinrich G.E. Christensen KG | Device for intra-anal application of medicaments in liquid or pasty form |
AT377916B (en) * | 1983-01-20 | 1985-05-28 | Laske Gerfried Dr | TAPERED DEVICE FOR TREATING THE ANAL AREA |
US4573981A (en) * | 1983-10-24 | 1986-03-04 | Mcfarlane Richard H | Protective sheath structure for a catheter assembly |
US4906239A (en) * | 1982-05-26 | 1990-03-06 | Wilhelm Bruhl | Hemorrhoid-treatment rod |
US5380300A (en) * | 1993-08-19 | 1995-01-10 | Smithkline Beecham | Douche nozzle |
US5843043A (en) * | 1997-03-25 | 1998-12-01 | Markus; George | Syringe and process for dispensing treatment fluid |
USD421120S (en) * | 1998-08-21 | 2000-02-22 | Pharmacia & Upjohn Company | Spray bottle grip |
USD428141S (en) * | 1999-08-04 | 2000-07-11 | Pharmacia & Upjohn Company | Spray bottle grip |
US6276568B1 (en) | 1998-08-21 | 2001-08-21 | Pharmacia & Upjohn Company | Spray bottle grip |
US20040039352A1 (en) * | 2002-06-28 | 2004-02-26 | Paul Bergeson | Nasal dosing device |
US20040127861A1 (en) * | 2002-12-26 | 2004-07-01 | Bradley Pharmaceuticals, Inc. | Method and apparatus for dispensing a composition |
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US7473245B2 (en) * | 2003-01-30 | 2009-01-06 | Sorin Group Deutschland Gmbh | Aortic cannula |
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US20120035559A1 (en) * | 2010-08-09 | 2012-02-09 | Rucinski Paul J | Device and Method for Abscess Irrigation |
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US3439675A (en) * | 1966-06-14 | 1969-04-22 | Becton Dickinson Co | Deformable needle assembly |
US3838681A (en) * | 1972-12-29 | 1974-10-01 | J Dalton | Device for collection of cells from the vagina |
US4453935A (en) * | 1982-04-16 | 1984-06-12 | Chester Labs, Inc. | Disposable container-applicator with leak-proof cover |
US4906239A (en) * | 1982-05-26 | 1990-03-06 | Wilhelm Bruhl | Hemorrhoid-treatment rod |
AT377916B (en) * | 1983-01-20 | 1985-05-28 | Laske Gerfried Dr | TAPERED DEVICE FOR TREATING THE ANAL AREA |
DE3406829A1 (en) * | 1983-03-25 | 1984-09-27 | Neopac AG, Oberdiessbach | Device for the application of a liquid to pasty product in body orifices, and a method of producing and operating the same |
AT392009B (en) * | 1983-03-25 | 1991-01-10 | Neopac Ag | DEVICE FOR APPLYING A LIQUID TO PASTE-SHAPED PREPARATE IN BODY OPENINGS, ESPECIALLY FOR RECTAL APPLICATION |
EP0139855A1 (en) * | 1983-07-08 | 1985-05-08 | PLANTORGAN WERK Heinrich G.E. Christensen KG | Device for intra-anal application of medicaments in liquid or pasty form |
US4573981A (en) * | 1983-10-24 | 1986-03-04 | Mcfarlane Richard H | Protective sheath structure for a catheter assembly |
US5380300A (en) * | 1993-08-19 | 1995-01-10 | Smithkline Beecham | Douche nozzle |
US5843043A (en) * | 1997-03-25 | 1998-12-01 | Markus; George | Syringe and process for dispensing treatment fluid |
USD421120S (en) * | 1998-08-21 | 2000-02-22 | Pharmacia & Upjohn Company | Spray bottle grip |
US6276568B1 (en) | 1998-08-21 | 2001-08-21 | Pharmacia & Upjohn Company | Spray bottle grip |
US6386397B2 (en) | 1998-08-21 | 2002-05-14 | Pharmacia & Upjohn Company | Spray bottle grip |
USD428141S (en) * | 1999-08-04 | 2000-07-11 | Pharmacia & Upjohn Company | Spray bottle grip |
US20040039352A1 (en) * | 2002-06-28 | 2004-02-26 | Paul Bergeson | Nasal dosing device |
US20040127861A1 (en) * | 2002-12-26 | 2004-07-01 | Bradley Pharmaceuticals, Inc. | Method and apparatus for dispensing a composition |
US20070118083A1 (en) * | 2002-12-26 | 2007-05-24 | Bradley Pharmaceuticals, Inc. | Method and apparatus for dispensing a composition |
US20090048579A1 (en) * | 2002-12-26 | 2009-02-19 | Nycomed Us Inc. | Method and apparatus for dispensing a composition |
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US7473245B2 (en) * | 2003-01-30 | 2009-01-06 | Sorin Group Deutschland Gmbh | Aortic cannula |
US20070197958A1 (en) * | 2005-09-22 | 2007-08-23 | Contura Sa | Probe for insertion in the anal canal and rectum of a body |
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