US2697438A - Noncoring hypodermic needle - Google Patents
Noncoring hypodermic needle Download PDFInfo
- Publication number
- US2697438A US2697438A US386448A US38644853A US2697438A US 2697438 A US2697438 A US 2697438A US 386448 A US386448 A US 386448A US 38644853 A US38644853 A US 38644853A US 2697438 A US2697438 A US 2697438A
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- US
- United States
- Prior art keywords
- cannula
- point
- needle
- noncoring
- hypodermic needle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3286—Needle tip design, e.g. for improved penetration
Definitions
- This invention relates to a hypodermic needle and more particularly to the shape of the pointed end of the needle.
- An object of the invention is to provide a non-coring needle which permits and does not restrict the free passage of fluid through the pointed end into and out of the lumen of the needle or passageway through the cannula.
- a further object of the invention is to provide a needle in which the penetrating point is in the center line or axis of the cannula.
- Fig. 1 is a side elevational view of a double pointed needle, the left hand pointed end of which is shaped and constructed in accordance with the invention
- Fig. 2 is an enlarged side elevational view of the left hand end of the needle shown in Fig. 1,
- Fig. 3 is an enlarged plan view of the left hand end of the needle shown in Fig. 1 and Fig. 4 is an enlarged end view of the left hand end of the needle shown in Fig. 1.
- 1 is the cannula which has right cylindrical outer and inner surfaces
- 2 is any suitable pointed end such as the conventional end formed by cutting the straight cylindrical cannula on a plane which is oblique to the axis of the cannula
- 3 is a knurled hub secured to the cannula
- 4 is the pointed end in accordance with the invention.
- the penetrating point 5, i. e. the extreme end of the pointed end of the needle lies in the axis of the cannula as appears from its coincidence with the axis line A-A.
- the closed side 6 of the pointed end curves gradually from the cylindrical portion of the cannula 1 to the point as appears in Figs. 1, 2 and 4 but does not extend outwardly with respect to the axis beyond an imaginary projection of the outer cylindrical surface of the cannula.
- the pointed end consists of the cylindrical surface 8 which extends forwardly toward the point 5 from the heel 9 and the bevel surfaces 10 which extend forwardly from the surface 8 to the point 5.
- the shape of the open side of the pointed end of the needle may be visualized by considering that it is formed by first bending the end of the cannula to produce the curvature of the closed side 6 as seen in Fig. 2, then cutting away the other side of the curved end to produce a substantially cylindrical surface curving inwardly toward the curved surface 6 and extending from the heel 9, which is at the point of intersection of the cylindrical outer surface of the straight portion of the cannula with said cut cylindrical surface, to a point adjacent the penetrating point 5 and finally beveling the cut wall of the cannula from the point 5 rearwardly on each side of the opening 7 to points about one half to three fifths of the length of the opening 7.
- the intersection of the resulting bevelled surfaces 10 with each other is at the line 11 and the intersections of the bevelled surfaces with the surface 8 are at the lines 12, 12. It is preferable to bevel the cut walls of the cannula so that the bevelled surfaces 10, 10 merge into the surface 8 with little or no The open side of Patent ice ridge at the intersection.
- the bevelled surfaces 10, 10 may extend all the way across the cut wall of the cannula as shown in Fig. 3 or only partly across said cut wall.
- the curved surface 8 and the curved bevelled Zurfzges 10, 10 do not dip substantially below the axis
- the above described design provides a penetrating point which is at the axis of the cannula.
- the location of the penetrating point below the imaginary extension of the outer cylindrical surface of the cannula and the con cave curvature of the surface 8, 10, 10 facilitate the unrestricted flow of liquid through the opening 7 because, due to the curvature of the surface 8, 10, 10 the surrounding tissue will not be tightly pressed against all portions, thereof particularly the middle portion of said surface.
- the penetrating point is formed by the converging surfaces 6 and 10, 10 so that as the point penetrates it will spread the penetrated tissue in all directions. This minimizes the force required for penetration.
- the opening cut by the point and the adjacent edges is spread substantially equally by the surface 6 on one side and the surfaces 8, 10, 10 on the other side.
- the location of the penetrating point at the axis of the cannula also reduces the tendency to coring by the forward edge of the surface 8.
- the shape of the point does not prevent the use of a cleaning wire because the cross section of the opening 7 is in alinernent with a substantial part of the lumen of the cannula as a pears in Fig. 4.
- the point design of the present invention possesses all of the advantages and wholly or partially eliminates the disadvantages of conventional needle points of the prior art in which the opening is either completely in alinement with the lumen as in the case of the point 2 described above or completely out of alinernent with the lumen as in the case of a needle in which the plane surface surrounding the opening is tangent to the outer cylindrical surface of the cannula. or in which the point is conical with the opening in the side wall thereof.
- the advantages of the needle point are attributed to the combination of the curvature of the surface 8, 10, 10 with the axial location of the penetrating point.
- a hypodermic needle comprising a cannula and an integral pointed end, said cannula having right cylindrical outer and inner surfaces, said pointed end having an open side, a closed side and a penetrating front located substantially in the longitudinal axis of the cannula, the median line of said closed side being curved outwardly with respect to a straight line extending from the penetrating point to the end of said outer cylindrical surface, said open side comprising a surface surrounding an opening communicating with the lumen of the cannula, the last named surface curving inwardly with respect to a straight line extending from the penetrating point to the end of said outer cylindrical surface of the cannula, the surface of said open side of said pointed end comprising a substantially cylindrical portion adjacent said outer cylindrical surface of the cannula and oppositely bevelled surfaces adjacent said penetrating point.
Description
Dec. 21, 1954 M KEY 2,697,438
NONCORING HYPODERMIC NEEDLE Filed Oct. 16, 1953 INVENTOR gamjgh. BY W WP P fl ww a/PAVL ATTORNEYS United NONCORING HYPODERMIC NEEDLE Application October 16, 1953, Serial No. 386,448
1 Claim. (Cl. 128-221) This invention relates to a hypodermic needle and more particularly to the shape of the pointed end of the needle.
An object of the invention is to provide a non-coring needle which permits and does not restrict the free passage of fluid through the pointed end into and out of the lumen of the needle or passageway through the cannula.
A further object of the invention is to provide a needle in which the penetrating point is in the center line or axis of the cannula.
The invention is illustrated in the accompanying drawings in which Fig. 1 is a side elevational view of a double pointed needle, the left hand pointed end of which is shaped and constructed in accordance with the invention,
Fig. 2 is an enlarged side elevational view of the left hand end of the needle shown in Fig. 1,
Fig. 3 is an enlarged plan view of the left hand end of the needle shown in Fig. 1 and Fig. 4 is an enlarged end view of the left hand end of the needle shown in Fig. 1.
Referring to Fig. 1, 1 is the cannula which has right cylindrical outer and inner surfaces, 2 is any suitable pointed end such as the conventional end formed by cutting the straight cylindrical cannula on a plane which is oblique to the axis of the cannula, 3 is a knurled hub secured to the cannula and 4 is the pointed end in accordance with the invention.
As appears in Fig. 2, the penetrating point 5, i. e. the extreme end of the pointed end of the needle lies in the axis of the cannula as appears from its coincidence with the axis line A-A. The closed side 6 of the pointed end curves gradually from the cylindrical portion of the cannula 1 to the point as appears in Figs. 1, 2 and 4 but does not extend outwardly with respect to the axis beyond an imaginary projection of the outer cylindrical surface of the cannula. the pointed end consists of the cylindrical surface 8 which extends forwardly toward the point 5 from the heel 9 and the bevel surfaces 10 which extend forwardly from the surface 8 to the point 5. The shape of the open side of the pointed end of the needle may be visualized by considering that it is formed by first bending the end of the cannula to produce the curvature of the closed side 6 as seen in Fig. 2, then cutting away the other side of the curved end to produce a substantially cylindrical surface curving inwardly toward the curved surface 6 and extending from the heel 9, which is at the point of intersection of the cylindrical outer surface of the straight portion of the cannula with said cut cylindrical surface, to a point adjacent the penetrating point 5 and finally beveling the cut wall of the cannula from the point 5 rearwardly on each side of the opening 7 to points about one half to three fifths of the length of the opening 7. The intersection of the resulting bevelled surfaces 10 with each other is at the line 11 and the intersections of the bevelled surfaces with the surface 8 are at the lines 12, 12. It is preferable to bevel the cut walls of the cannula so that the bevelled surfaces 10, 10 merge into the surface 8 with little or no The open side of Patent ice ridge at the intersection. The bevelled surfaces 10, 10 may extend all the way across the cut wall of the cannula as shown in Fig. 3 or only partly across said cut wall. The curved surface 8 and the curved bevelled Zurfzges 10, 10 do not dip substantially below the axis The above described design provides a penetrating point which is at the axis of the cannula. The location of the penetrating point below the imaginary extension of the outer cylindrical surface of the cannula and the con cave curvature of the surface 8, 10, 10 facilitate the unrestricted flow of liquid through the opening 7 because, due to the curvature of the surface 8, 10, 10 the surrounding tissue will not be tightly pressed against all portions, thereof particularly the middle portion of said surface. The penetrating point is formed by the converging surfaces 6 and 10, 10 so that as the point penetrates it will spread the penetrated tissue in all directions. This minimizes the force required for penetration. The opening cut by the point and the adjacent edges is spread substantially equally by the surface 6 on one side and the surfaces 8, 10, 10 on the other side. The location of the penetrating point at the axis of the cannula also reduces the tendency to coring by the forward edge of the surface 8. The shape of the point does not prevent the use of a cleaning wire because the cross section of the opening 7 is in alinernent with a substantial part of the lumen of the cannula as a pears in Fig. 4. The point design of the present invention possesses all of the advantages and wholly or partially eliminates the disadvantages of conventional needle points of the prior art in which the opening is either completely in alinement with the lumen as in the case of the point 2 described above or completely out of alinernent with the lumen as in the case of a needle in which the plane surface surrounding the opening is tangent to the outer cylindrical surface of the cannula. or in which the point is conical with the opening in the side wall thereof. The advantages of the needle point are attributed to the combination of the curvature of the surface 8, 10, 10 with the axial location of the penetrating point.
It is within the scope of my invention to make the surface 6 straight instead of curved and to omit the bevels 10, 10.
I claim:
A hypodermic needle comprising a cannula and an integral pointed end, said cannula having right cylindrical outer and inner surfaces, said pointed end having an open side, a closed side and a penetrating front located substantially in the longitudinal axis of the cannula, the median line of said closed side being curved outwardly with respect to a straight line extending from the penetrating point to the end of said outer cylindrical surface, said open side comprising a surface surrounding an opening communicating with the lumen of the cannula, the last named surface curving inwardly with respect to a straight line extending from the penetrating point to the end of said outer cylindrical surface of the cannula, the surface of said open side of said pointed end comprising a substantially cylindrical portion adjacent said outer cylindrical surface of the cannula and oppositely bevelled surfaces adjacent said penetrating point.
References Cited in the file of this patent UNITED STATES PATENTS Number Name Date 2,409,979 Huber Oct. 22, 1946 2,562,129 Scherer et a1. July 24, 1951 FOREIGN PATENTS Number Country Date 137,455 Great Britain Ian. 15, 1920
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US386448A US2697438A (en) | 1953-10-16 | 1953-10-16 | Noncoring hypodermic needle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US386448A US2697438A (en) | 1953-10-16 | 1953-10-16 | Noncoring hypodermic needle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US2697438A true US2697438A (en) | 1954-12-21 |
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ID=23525616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US386448A Expired - Lifetime US2697438A (en) | 1953-10-16 | 1953-10-16 | Noncoring hypodermic needle |
Country Status (1)
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|---|---|
| US (1) | US2697438A (en) |
Cited By (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2989053A (en) * | 1956-01-17 | 1961-06-20 | Baxter Don Inc | Hypodermic needle |
| US3063451A (en) * | 1959-09-28 | 1962-11-13 | Arthur J Kowalk | Self-venting type needle |
| US3540112A (en) * | 1967-01-18 | 1970-11-17 | Knox Lab Inc | Method for manufacturing a hypodermic needle |
| US3633580A (en) * | 1967-01-18 | 1972-01-11 | Knox Lab Inc | Hypodermic needle |
| US3893445A (en) * | 1974-01-09 | 1975-07-08 | Becton Dickinson Co | Bone marrow biopsy instrument |
| US3924617A (en) * | 1973-09-28 | 1975-12-09 | Crinospital Spa | Aspiration and infusion needle |
| FR2481930A1 (en) * | 1980-05-06 | 1981-11-13 | Villette Alain | Hypodermic needle having coaxial point - for ease of insertion by rotary drill without plugging |
| US4383530A (en) * | 1981-06-05 | 1983-05-17 | John Bruno | Hypodermic needle and method of making needles |
| EP0301246A1 (en) * | 1987-07-10 | 1989-02-01 | B. Braun Melsungen AG | Cannula |
| DE4109442A1 (en) * | 1991-03-22 | 1992-09-24 | Haindl Hans | Steel syringe for spinal anaesthesia - has external and passage diameters tapering to insertion point and aperture |
| WO1994003223A1 (en) * | 1992-08-10 | 1994-02-17 | Hans Haindl | Cannula |
| US5520193A (en) * | 1993-02-22 | 1996-05-28 | Issei Suzuki | Blood collecting needle with vein indicator |
| US5536259A (en) * | 1995-07-28 | 1996-07-16 | Medisystems Technology Corp | Hypodermic cannula |
| DE19512607A1 (en) * | 1995-04-04 | 1996-10-10 | Johann Dr Med Rull | Completely tragmentation-free cannulas |
| US6012213A (en) * | 1995-06-07 | 2000-01-11 | Chang; Joseph J. | Method for forming a rib on a cannula for a tip protection device |
| US20020106813A1 (en) * | 2001-01-26 | 2002-08-08 | Symyx Technologies, Inc. | Apparatus and methods for parallel processing of multiple reaction mixtures |
| US20020110493A1 (en) * | 1998-08-13 | 2002-08-15 | Symyx Technologies , Inc | Apparatus and methods for parallel processing of multiple reaction mixtures |
| US20040111066A1 (en) * | 1996-06-20 | 2004-06-10 | Becton, Dickinson And Company | Mult-beveled point needle and syringe having a multi-beveled point needle |
| WO2004064903A1 (en) * | 2003-01-21 | 2004-08-05 | Carmel Pharma Ab | A needle for penetrating a membrane |
| US20040153026A1 (en) * | 2002-12-13 | 2004-08-05 | Mackool Richard J. | Tapered infusion sleeve portal |
| US6802199B2 (en) | 1999-02-04 | 2004-10-12 | Integ, Inc. | Needle for body fluid tester |
| US20040241875A1 (en) * | 2001-01-26 | 2004-12-02 | Symyx Technologies, Inc. | Apparatus and methods for parallel processing of multiple reaction mixtures |
| US20050096594A1 (en) * | 2002-04-30 | 2005-05-05 | Doctor's Research Group, Incorporated | Cannula arrangements |
| US20070123935A1 (en) * | 2005-11-30 | 2007-05-31 | Myers Gene E | Method and apparatus for contemporaneous formation of a body structure opening and homologous pedicle |
| US20090099535A1 (en) * | 2005-06-20 | 2009-04-16 | Yuean Wang | Disposable Needle for Syringes and Infusions and the Manufacture Thereof |
| US7867215B2 (en) | 2002-04-17 | 2011-01-11 | Carmel Pharma Ab | Method and device for fluid transfer in an infusion system |
| USD637713S1 (en) | 2009-11-20 | 2011-05-10 | Carmel Pharma Ab | Medical device adaptor |
| US7942860B2 (en) | 2007-03-16 | 2011-05-17 | Carmel Pharma Ab | Piercing member protection device |
| US7975733B2 (en) | 2007-05-08 | 2011-07-12 | Carmel Pharma Ab | Fluid transfer device |
| US8029747B2 (en) | 2007-06-13 | 2011-10-04 | Carmel Pharma Ab | Pressure equalizing device, receptacle and method |
| US8075550B2 (en) | 2008-07-01 | 2011-12-13 | Carmel Pharma Ab | Piercing member protection device |
| US8162013B2 (en) | 2010-05-21 | 2012-04-24 | Tobias Rosenquist | Connectors for fluid containers |
| US8287513B2 (en) | 2007-09-11 | 2012-10-16 | Carmel Pharma Ab | Piercing member protection device |
| US8480646B2 (en) | 2009-11-20 | 2013-07-09 | Carmel Pharma Ab | Medical device connector |
| US8523838B2 (en) | 2008-12-15 | 2013-09-03 | Carmel Pharma Ab | Connector device |
| US8545475B2 (en) | 2002-07-09 | 2013-10-01 | Carmel Pharma Ab | Coupling component for transmitting medical substances |
| US8562583B2 (en) | 2002-03-26 | 2013-10-22 | Carmel Pharma Ab | Method and assembly for fluid transfer and drug containment in an infusion system |
| US8622985B2 (en) | 2007-06-13 | 2014-01-07 | Carmel Pharma Ab | Arrangement for use with a medical device |
| US8657803B2 (en) | 2007-06-13 | 2014-02-25 | Carmel Pharma Ab | Device for providing fluid to a receptacle |
| US8790330B2 (en) | 2008-12-15 | 2014-07-29 | Carmel Pharma Ab | Connection arrangement and method for connecting a medical device to the improved connection arrangement |
| US8827978B2 (en) | 2007-09-17 | 2014-09-09 | Carmel Pharma Ab | Bag connector |
| US8852091B2 (en) | 2012-04-04 | 2014-10-07 | Alcon Research, Ltd. | Devices, systems, and methods for pupil expansion |
| US20150196747A1 (en) * | 2014-01-13 | 2015-07-16 | Heather Lee Alvarez | Buttonhole tool |
| US9168203B2 (en) | 2010-05-21 | 2015-10-27 | Carmel Pharma Ab | Connectors for fluid containers |
| US20160338734A1 (en) * | 2015-05-22 | 2016-11-24 | Dexcom, Inc. | Needle for transcutaneous analyte sensor delivery |
| WO2018010709A1 (en) * | 2016-07-15 | 2018-01-18 | Acti-Med Ag | Needle for piercing a membrane |
| CN109069737A (en) * | 2016-03-28 | 2018-12-21 | 泰尔茂株式会社 | The manufacturing method of medical puncture needle and puncture needle |
| US20190038877A1 (en) * | 2017-08-04 | 2019-02-07 | Becton, Dickinson And Company | Method and apparatus for introducing a needle for catheter placement |
| WO2019028318A1 (en) | 2017-08-04 | 2019-02-07 | Becton, Dickinson And Company | Needle and catheter insertion device |
| US10398834B2 (en) | 2007-08-30 | 2019-09-03 | Carmel Pharma Ab | Device, sealing member and fluid container |
| WO2019219480A1 (en) | 2018-05-17 | 2019-11-21 | Novo Nordisk A/S | A needle cannula with a grinded point |
| US11793942B2 (en) | 2014-12-11 | 2023-10-24 | Facet Technologies, Llc | Needle with multi-bevel tip geometry |
| US11944373B2 (en) * | 2012-10-29 | 2024-04-02 | Ablative Solutions, Inc. | Peri-vascular tissue ablation catheters |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB137455A (en) * | 1919-02-05 | 1920-01-15 | Andre Jousset | Improved combined phial and needle for hypodermic injections and other purposes |
| US2409979A (en) * | 1946-03-14 | 1946-10-22 | Ralph L Huber | Hypodermic needle |
| US2562129A (en) * | 1946-01-23 | 1951-07-24 | Scherer Corp R P | Hypodermic syringe |
-
1953
- 1953-10-16 US US386448A patent/US2697438A/en not_active Expired - Lifetime
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB137455A (en) * | 1919-02-05 | 1920-01-15 | Andre Jousset | Improved combined phial and needle for hypodermic injections and other purposes |
| US2562129A (en) * | 1946-01-23 | 1951-07-24 | Scherer Corp R P | Hypodermic syringe |
| US2409979A (en) * | 1946-03-14 | 1946-10-22 | Ralph L Huber | Hypodermic needle |
Cited By (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2989053A (en) * | 1956-01-17 | 1961-06-20 | Baxter Don Inc | Hypodermic needle |
| US3063451A (en) * | 1959-09-28 | 1962-11-13 | Arthur J Kowalk | Self-venting type needle |
| US3540112A (en) * | 1967-01-18 | 1970-11-17 | Knox Lab Inc | Method for manufacturing a hypodermic needle |
| US3633580A (en) * | 1967-01-18 | 1972-01-11 | Knox Lab Inc | Hypodermic needle |
| US3924617A (en) * | 1973-09-28 | 1975-12-09 | Crinospital Spa | Aspiration and infusion needle |
| US3893445A (en) * | 1974-01-09 | 1975-07-08 | Becton Dickinson Co | Bone marrow biopsy instrument |
| FR2481930A1 (en) * | 1980-05-06 | 1981-11-13 | Villette Alain | Hypodermic needle having coaxial point - for ease of insertion by rotary drill without plugging |
| US4383530A (en) * | 1981-06-05 | 1983-05-17 | John Bruno | Hypodermic needle and method of making needles |
| EP0301246A1 (en) * | 1987-07-10 | 1989-02-01 | B. Braun Melsungen AG | Cannula |
| US4889529A (en) * | 1987-07-10 | 1989-12-26 | B. Braun Melsungen Ag | Needle |
| DE4109442A1 (en) * | 1991-03-22 | 1992-09-24 | Haindl Hans | Steel syringe for spinal anaesthesia - has external and passage diameters tapering to insertion point and aperture |
| WO1994003223A1 (en) * | 1992-08-10 | 1994-02-17 | Hans Haindl | Cannula |
| US5520193A (en) * | 1993-02-22 | 1996-05-28 | Issei Suzuki | Blood collecting needle with vein indicator |
| DE19512607A1 (en) * | 1995-04-04 | 1996-10-10 | Johann Dr Med Rull | Completely tragmentation-free cannulas |
| US6012213A (en) * | 1995-06-07 | 2000-01-11 | Chang; Joseph J. | Method for forming a rib on a cannula for a tip protection device |
| US6213989B1 (en) | 1995-07-28 | 2001-04-10 | Dsu Medical Corporation | Hypodermic cannula |
| US5536259A (en) * | 1995-07-28 | 1996-07-16 | Medisystems Technology Corp | Hypodermic cannula |
| US20040111066A1 (en) * | 1996-06-20 | 2004-06-10 | Becton, Dickinson And Company | Mult-beveled point needle and syringe having a multi-beveled point needle |
| US7468055B2 (en) * | 1996-06-20 | 2008-12-23 | Becton Dickinson And Company | Multi-beveled point needle and syringe having a multi-beveled point needle |
| US20020110493A1 (en) * | 1998-08-13 | 2002-08-15 | Symyx Technologies , Inc | Apparatus and methods for parallel processing of multiple reaction mixtures |
| US6913934B2 (en) * | 1998-08-13 | 2005-07-05 | Symyx Technologies, Inc. | Apparatus and methods for parallel processing of multiple reaction mixtures |
| US6802199B2 (en) | 1999-02-04 | 2004-10-12 | Integ, Inc. | Needle for body fluid tester |
| US20040236249A1 (en) * | 1999-02-04 | 2004-11-25 | Hilgers Michael Edward | Needle for body fluid tester |
| US7858049B2 (en) | 2001-01-26 | 2010-12-28 | Freeslate, Inc. | Apparatus and methods for parallel processing of multiple reaction mixtures |
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| US20080138260A1 (en) * | 2001-01-26 | 2008-06-12 | Symyx Technologies, Inc | Apparatus and methods for parallel processing of multiple reaction mixtures |
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| US7335513B2 (en) | 2001-01-26 | 2008-02-26 | Symyx Technologies, Inc. | Apparatus and methods for parallel processing of multiple reaction mixtures |
| US8562583B2 (en) | 2002-03-26 | 2013-10-22 | Carmel Pharma Ab | Method and assembly for fluid transfer and drug containment in an infusion system |
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| US7867215B2 (en) | 2002-04-17 | 2011-01-11 | Carmel Pharma Ab | Method and device for fluid transfer in an infusion system |
| US20050096594A1 (en) * | 2002-04-30 | 2005-05-05 | Doctor's Research Group, Incorporated | Cannula arrangements |
| US8545475B2 (en) | 2002-07-09 | 2013-10-01 | Carmel Pharma Ab | Coupling component for transmitting medical substances |
| US9039672B2 (en) | 2002-07-09 | 2015-05-26 | Carmel Pharma Ab | Coupling component for transmitting medical substances |
| US7014629B2 (en) * | 2002-12-13 | 2006-03-21 | Alcon, Inc | Tapered infusion sleeve portal |
| US20040153026A1 (en) * | 2002-12-13 | 2004-08-05 | Mackool Richard J. | Tapered infusion sleeve portal |
| WO2004064903A1 (en) * | 2003-01-21 | 2004-08-05 | Carmel Pharma Ab | A needle for penetrating a membrane |
| JP2006514874A (en) * | 2003-01-21 | 2006-05-18 | カルメル プハルマ アクチボラゲット | Needle for piercing the membrane |
| US8328772B2 (en) * | 2003-01-21 | 2012-12-11 | Carmel Pharma Ab | Needle for penetrating a membrane |
| US20090099535A1 (en) * | 2005-06-20 | 2009-04-16 | Yuean Wang | Disposable Needle for Syringes and Infusions and the Manufacture Thereof |
| US20070123935A1 (en) * | 2005-11-30 | 2007-05-31 | Myers Gene E | Method and apparatus for contemporaneous formation of a body structure opening and homologous pedicle |
| US8381776B2 (en) | 2007-03-16 | 2013-02-26 | Carmel Pharma Ab | Piercing member protection device |
| US7942860B2 (en) | 2007-03-16 | 2011-05-17 | Carmel Pharma Ab | Piercing member protection device |
| US7975733B2 (en) | 2007-05-08 | 2011-07-12 | Carmel Pharma Ab | Fluid transfer device |
| US8225826B2 (en) | 2007-05-08 | 2012-07-24 | Carmel Pharma Ab | Fluid transfer device |
| US9309020B2 (en) | 2007-06-13 | 2016-04-12 | Carmel Pharma Ab | Device for providing fluid to a receptacle |
| US8029747B2 (en) | 2007-06-13 | 2011-10-04 | Carmel Pharma Ab | Pressure equalizing device, receptacle and method |
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