US232807A - Herbert e - Google Patents
Herbert e Download PDFInfo
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- US232807A US232807A US232807DA US232807A US 232807 A US232807 A US 232807A US 232807D A US232807D A US 232807DA US 232807 A US232807 A US 232807A
- Authority
- US
- United States
- Prior art keywords
- nerves
- chloral
- glycerine
- compound
- pain
- Prior art date
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- Expired - Lifetime
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- 150000001875 compounds Chemical class 0.000 description 30
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 18
- 235000011187 glycerol Nutrition 0.000 description 18
- HFFLGKNGCAIQMO-UHFFFAOYSA-N Chloral Chemical compound ClC(Cl)(Cl)C=O HFFLGKNGCAIQMO-UHFFFAOYSA-N 0.000 description 16
- 239000000126 substance Substances 0.000 description 14
- 239000000730 antalgic agent Substances 0.000 description 12
- 239000003518 caustics Substances 0.000 description 10
- 239000002274 desiccant Substances 0.000 description 10
- 239000004615 ingredient Substances 0.000 description 10
- 239000000203 mixture Substances 0.000 description 10
- 210000004268 Dentin Anatomy 0.000 description 8
- 239000001263 FEMA 3042 Substances 0.000 description 8
- 229940033123 Tannic Acid Drugs 0.000 description 8
- LRBQNJMCXXYXIU-NRMVVENXSA-N Tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 description 8
- 239000003921 oil Substances 0.000 description 8
- KWYUFKZDYYNOTN-UHFFFAOYSA-M potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 8
- 235000015523 tannic acid Nutrition 0.000 description 8
- 229920002258 tannic acid Polymers 0.000 description 8
- DSSYKIVIOFKYAU-UHFFFAOYSA-N Camphor Chemical compound C1CC2(C)C(=O)CC1C2(C)C DSSYKIVIOFKYAU-UHFFFAOYSA-N 0.000 description 6
- 229960000846 Camphor Drugs 0.000 description 6
- 241000723346 Cinnamomum camphora Species 0.000 description 6
- VXMKYRQZQXVKGB-CWWHNZPOSA-N Tannin Chemical compound O([C@H]1[C@H]([C@@H]2OC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)O[C@H]([C@H]2O)O1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 VXMKYRQZQXVKGB-CWWHNZPOSA-N 0.000 description 6
- 230000002745 absorbent Effects 0.000 description 6
- 239000002250 absorbent Substances 0.000 description 6
- 229930007890 camphor Natural products 0.000 description 6
- 239000011248 coating agent Substances 0.000 description 6
- 238000000576 coating method Methods 0.000 description 6
- 239000012530 fluid Substances 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 6
- 229920001864 tannin Polymers 0.000 description 6
- 239000001648 tannin Substances 0.000 description 6
- 235000018553 tannin Nutrition 0.000 description 6
- HCHKCACWOHOZIP-UHFFFAOYSA-N zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 6
- 229910052725 zinc Inorganic materials 0.000 description 6
- 239000011701 zinc Substances 0.000 description 6
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butanoic acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 4
- 210000001736 Capillaries Anatomy 0.000 description 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate dianion Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 4
- 210000003298 Dental Enamel Anatomy 0.000 description 4
- LNTHITQWFMADLM-UHFFFAOYSA-N Gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 4
- 229920002456 HOTAIR Polymers 0.000 description 4
- BQJCRHHNABKAKU-KBQPJGBKSA-N Morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 description 4
- GRLPQNLYRHEGIJ-UHFFFAOYSA-J Potassium alum Chemical compound [Al+3].[K+].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O GRLPQNLYRHEGIJ-UHFFFAOYSA-J 0.000 description 4
- 239000003212 astringent agent Substances 0.000 description 4
- XTEGARKTQYYJKE-UHFFFAOYSA-M chlorate Chemical compound [O-]Cl(=O)=O XTEGARKTQYYJKE-UHFFFAOYSA-M 0.000 description 4
- HEDRZPFGACZZDS-UHFFFAOYSA-N chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- 230000000149 penetrating Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- OXVISHZELPRKFQ-UHFFFAOYSA-N 2,2,3-trichlorobutanal Chemical compound CC(Cl)C(Cl)(Cl)C=O OXVISHZELPRKFQ-UHFFFAOYSA-N 0.000 description 2
- 239000004215 Carbon black (E152) Substances 0.000 description 2
- 235000005241 Cistus ladanifer Nutrition 0.000 description 2
- 240000008772 Cistus ladanifer Species 0.000 description 2
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 2
- 235000006965 Commiphora myrrha Nutrition 0.000 description 2
- 240000007311 Commiphora myrrha Species 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 2
- 229960002126 Creosote Drugs 0.000 description 2
- IDNUEBSJWINEMI-UHFFFAOYSA-N Ethyl nitrate Chemical compound CCO[N+]([O-])=O IDNUEBSJWINEMI-UHFFFAOYSA-N 0.000 description 2
- 229940074391 Gallic acid Drugs 0.000 description 2
- 235000006173 Larrea tridentata Nutrition 0.000 description 2
- 240000007588 Larrea tridentata Species 0.000 description 2
- 235000007265 Myrrhis odorata Nutrition 0.000 description 2
- 231100000614 Poison Toxicity 0.000 description 2
- 241000282941 Rangifer tarandus Species 0.000 description 2
- 210000002966 Serum Anatomy 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 235000016639 Syzygium aromaticum Nutrition 0.000 description 2
- 240000005147 Syzygium aromaticum Species 0.000 description 2
- 235000015450 Tilia cordata Nutrition 0.000 description 2
- 235000011941 Tilia x europaea Nutrition 0.000 description 2
- 229940046282 Zinc Drugs 0.000 description 2
- 229940091251 Zinc Supplements Drugs 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 229940037003 alum Drugs 0.000 description 2
- 230000003444 anaesthetic Effects 0.000 description 2
- 210000003484 anatomy Anatomy 0.000 description 2
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 2
- 229910052785 arsenic Inorganic materials 0.000 description 2
- BDOSMKKIYDKNTQ-UHFFFAOYSA-N cadmium Chemical compound [Cd] BDOSMKKIYDKNTQ-UHFFFAOYSA-N 0.000 description 2
- 229910052793 cadmium Inorganic materials 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
- 239000000460 chlorine Substances 0.000 description 2
- 229910052801 chlorine Inorganic materials 0.000 description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 239000003974 emollient agent Substances 0.000 description 2
- 235000004515 gallic acid Nutrition 0.000 description 2
- 150000002430 hydrocarbons Chemical class 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 239000011133 lead Substances 0.000 description 2
- 239000004571 lime Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000004570 mortar (masonry) Substances 0.000 description 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- 229940072033 potash Drugs 0.000 description 2
- 235000015320 potassium carbonate Nutrition 0.000 description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Substances [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
- 230000002035 prolonged Effects 0.000 description 2
- 238000009877 rendering Methods 0.000 description 2
- 239000012047 saturated solution Substances 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 239000004328 sodium tetraborate Substances 0.000 description 2
- 235000010339 sodium tetraborate Nutrition 0.000 description 2
- 235000015096 spirit Nutrition 0.000 description 2
- 235000011149 sulphuric acid Nutrition 0.000 description 2
- 239000001117 sulphuric acid Substances 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
Definitions
- My invention relates to that class of dental compounds or preparations which are employed to prevent pain in filling teeth, or during the process of excavating or preparing the cavities to receive the filling; and it consists in a novel combination of ingredients, as hereinafter more fully set forth and claimed, by which a more effective article of this character is produced than is now in ordinary use.
- a tooth consists of three principal parts viz., the enamel or outer coating, the dentine or body, and the pulp or center. Connected with the pulp and extending throughout the body are a series of minute and extremely sen- 0 sitive nerves, which, when exposed to the air or brought into contact with foreign substances, cause more or less pain. Hence when decay takes place, and it becomes necessary to fill the cavity produced thereby, the pain 3 5 caused by the instruments being broughtinto contact with the exposed nerves in excavating the cavity is sometimes very intense, and freqently interferes materially with the work of v the dentist.
- the pain may be lessened. It may also be reduced by means of powerful astringents and caustics; also, by the direct application of substances possessing obtundent properties, and by the use of anaesthetics or anodynes.
- adesiccant hot air has been employed with some success, being forced or injected into the cavity by means of a proper pump or instrument designed for that purpose; but as hot air can be brought into contact with the surface only, the relief afforded is not always certain and always but 5 partial.
- surfacc-desiccants such, for instance, as burnt alum, carbonate of potassa, &c., their action being mainly superfiroo cial, as they possess very slight, if any, capillary or penetrative properties, their astringent or caustic action tending to greatly limit their absorbent action when used as indicated--anobjection which applies with equal force to various other metallic and vegetable substances possessing absorbent, or absorbent and astringent, properties which have been tried for the same purpose.
- the desiccant should possess few or no astringent properties, and should not act as a caustic or escharotic. It should also be of such anature as to readily penetrate the tubes or ducts of the dentine and absorb the fluids contained therein.
- the obtundent should be strictly what its name indicates, deadening sensibility by coating and sheathing the exposed nerves, producing at the same time a soothing demulcent effect.
- the astringent should be purely of an astringent nature without caustic properties, and the anodyne one that will have a prolonged action, or not be readily evaporated or dissipated in use. It is also equally important that none of these elements should, either by themselves or when combined, operate to injuriously affect the teeth or health.
- My improved compound is believed to possess in a marked degree all of the essential features mentioned, and is prepared as follows: Take of glycerine one fluid ounce; tannic acid, two drams chloral, four grains. Mix thoroughly by rubbing up all of the ingredients in a mortar or other suitable vessel, after which they must be strained or filtered until clear.
- the glycerine should be of the very best quality, free from water, lime, butyric acid, chlorine, chloride of calcium, lead, sulphuric acid, sugar, and all other adulterations or impurities.
- the tannic acid should also be pure and of full strength, the white being best, as it usually contains less gallic acid than the yellow.
- tannic acid may also be substituted by sulphate of zinc, sulphate of cadmium, and various other astringents; but the tannin is far superior in every respect to any similar article with which I am familiar, being very powerful and entirely harmless.
- glycerine As glycerine possesses remarkable capillary or penetrative powers and has an intense affinity for water, its peculiar value as a desiccant in this connection will be readily appreciated. It rapidly penetrates the dentine, absorbin g the contents of the tubes or ducts, and also all moisture from the cavity, at the same time serving as a perfect obtundent by sheathing or coating the exposed nerves, thus combining in itself two very essential features or elements of my invention-to wit, an obtundcut and a desiccant.
- the glycerine also acts as a vehicle by means of which the astringent and anodyne are brought more speedily and effectually into contact with the sensitive portions of the tooth than is possible by any other agent with which I am familiar.
- oils or oily compounds may be used in place of the glycerine, but are far less effectual in nearly every respect.
- the compound may In a dental compound for preventing pain be employed to prevent pain not only in prein excavating and preparing teeth for filling, paring the cavities and filling the same, but in the combination of glycerine, tannic acid, and numerous other operations on the teeth; also, chloral, substantially as set forth and speci- 5 that on account of its transparency it will not fied.
Description
NI'rEn STATES ATEN rricn,
HERBERT E. DENNETT, OF BOSTON, MASS, ASSIGNOR TO THE DENNETT DENTAL NABOLI' COMPANY, OF HARTFORD, CONN.
DENTAL COMPOUND FOR PREVENTING PAlN.
SPECIFICATION forming part of Letters Patent No. 232,807, dated October 5, 1880.
Application filed J annary 26, 1880. (Specimen) To all whom it may concern:
Be it known that I, HERBERT Enos DEN- NETT, of Boston, in the county of Suffolk, State of Massachusetts, have invented a cer tain new and useful Improvement in Dental Compounds, of which the following is a description sufficiently full, clear, and exact to enable any person skilled in the art or science to which my invention appertains to make and I0 use the same.
My invention relates to that class of dental compounds or preparations which are employed to prevent pain in filling teeth, or during the process of excavating or preparing the cavities to receive the filling; and it consists in a novel combination of ingredients, as hereinafter more fully set forth and claimed, by which a more effective article of this character is produced than is now in ordinary use.
As the structure or anatomy of the teeth is well understood by all practical dentists, a brief description of the same is all that is deemed necessary in order to show the nature of my improvement.
2 5 A tooth consists of three principal parts viz., the enamel or outer coating, the dentine or body, and the pulp or center. Connected with the pulp and extending throughout the body are a series of minute and extremely sen- 0 sitive nerves, which, when exposed to the air or brought into contact with foreign substances, cause more or less pain. Hence when decay takes place, and it becomes necessary to fill the cavity produced thereby, the pain 3 5 caused by the instruments being broughtinto contact with the exposed nerves in excavating the cavity is sometimes very intense, and freqently interferes materially with the work of v the dentist. To obviate this has long been the study of the profession, use having been made of a great variety of articles designed to produce deadening or anodyne effects on the nerves of the tooth, such as oil of cloves, creosote, camphor, spirits of nitric ether, borax,
4 5 carbolic acid, laudanum, chloroform, alum, myrrh, tinctures of iron, chloral, morphia, carbonate of potassa, sulphate of zinc, chlorate of potassa, &c., and also compounds embodying more or less of these ingredients. Caustic 5o preparations of arsenic, burnt alum, zinc, potash, acid, &c., have also been employed to kill or destroy the ner 'es; but, aside from the poisonous nature of some of the last named articles and the great dangerincurredin their use, it is now considered by nearly all scientific dentists very objectionable to destroy the nerves of the tooth when possible to avoid it.
In view of the foregoing I have for many years experimented constantly to discover a substance or compound that would produce, when directly applied, such an effectas to enable cavities to be properly excavated and filled without causing pain or killing or destroying the nerves of the teeth. These ex periments have disclosed the following facts having direct relation to my present invention, viz: The body or dentine of the tooth is formed or built up of superposed layers composed of infinitesimal tubes, between which layers and in immediate contact with the nerves there are a series of exceedingly small flattened tubes or ducts filled with serum, or a thin watery fluid, and extending through from the enamel to the pulp. These ducts, while in their normal state, act as liquid telegraphs, 7 so to speak, to convey along the line of the nerves the impulse or vibrations produced by the dental instruments used in excavating or preparing the cavity and filling the same, thus greatly increasing the sensitivity of the nerves, and rendering the operation much more painful.
By simply desiccating or drying the exposed surfaces in the cavity the pain may be lessened. It may also be reduced by means of powerful astringents and caustics; also, by the direct application of substances possessing obtundent properties, and by the use of anaesthetics or anodynes. As adesiccant, hot air has been employed with some success, being forced or injected into the cavity by means of a proper pump or instrument designed for that purpose; but as hot air can be brought into contact with the surface only, the relief afforded is not always certain and always but 5 partial. For the same reason several of the substances hereinbefore enumerated may be properly termed surfacc-desiccants, such, for instance, as burnt alum, carbonate of potassa, &c., their action being mainly superfiroo cial, as they possess very slight, if any, capillary or penetrative properties, their astringent or caustic action tending to greatly limit their absorbent action when used as indicated--anobjection which applies with equal force to various other metallic and vegetable substances possessing absorbent, or absorbent and astringent, properties which have been tried for the same purpose.
I have found, therefore, that in excavating and filling teeth an article designed to produce insensibility to pain by direct application to the cavity should, in order to accomplish the desired results,possess qualifications which do not pertain exclusively to any of the substances named, or to analogous substances or their compounds. I have also found that at least three elements, acting wholly or in a measure independently of each other, and producing somewhat different results, are essential in a compound or preparation of this character, and also that a fourth may sometimes be employed to advantage as auxiliary to the others, to wit: first, a desiccant; secondly, an obtundent; thirdly, an astringent; and, fourthly, an anodyne. These elements should also have certain peculiarities of their own, viz: The desiccant should possess few or no astringent properties, and should not act as a caustic or escharotic. It should also be of such anature as to readily penetrate the tubes or ducts of the dentine and absorb the fluids contained therein. The obtundent should be strictly what its name indicates, deadening sensibility by coating and sheathing the exposed nerves, producing at the same time a soothing demulcent effect. The astringent should be purely of an astringent nature without caustic properties, and the anodyne one that will have a prolonged action, or not be readily evaporated or dissipated in use. It is also equally important that none of these elements should, either by themselves or when combined, operate to injuriously affect the teeth or health.
My improved compound is believed to possess in a marked degree all of the essential features mentioned, and is prepared as follows: Take of glycerine one fluid ounce; tannic acid, two drams chloral, four grains. Mix thoroughly by rubbing up all of the ingredients in a mortar or other suitable vessel, after which they must be strained or filtered until clear. The glycerine should be of the very best quality, free from water, lime, butyric acid, chlorine, chloride of calcium, lead, sulphuric acid, sugar, and all other adulterations or impurities. The tannic acid should also be pure and of full strength, the white being best, as it usually contains less gallic acid than the yellow.
The proportions given in the above formula may be varied, as desired, without departing from the spirit of my invention, although I prefer in all cases to use a saturated solution of tannin and glycerine, the relative proportions of the last-named ingredients in such a solution being substantially as stated, or about four parts of glycerine to one of tannin. The amount of ordinary chloral required for one and one-fourth ounce of the compound is one grain; but I sometimes omit the anodyne entirely, and at others increase this quantity to five grains or more, or use butyl chloral instead where a stronger anodyne is indicated. Acetate of morphia and some other anodynes may be substituted for the chloral, or used in varying proportions therewith, but simple chloral is deemed preferable. I also sometimes employ camphor in place of chloral, as well asin combination with the same and the other ingredients, the camphor and chloral being used in nearly equal quantities. The tannic acid may also be substituted by sulphate of zinc, sulphate of cadmium, and various other astringents; but the tannin is far superior in every respect to any similar article with which I am familiar, being very powerful and entirely harmless.
As glycerine possesses remarkable capillary or penetrative powers and has an intense affinity for water, its peculiar value as a desiccant in this connection will be readily appreciated. It rapidly penetrates the dentine, absorbin g the contents of the tubes or ducts, and also all moisture from the cavity, at the same time serving as a perfect obtundent by sheathing or coating the exposed nerves, thus combining in itself two very essential features or elements of my invention-to wit, an obtundcut and a desiccant. The glycerine also acts as a vehicle by means of which the astringent and anodyne are brought more speedily and effectually into contact with the sensitive portions of the tooth than is possible by any other agent with which I am familiar.
Other oils or oily compounds may be used in place of the glycerine, but are far less effectual in nearly every respect. For instance, the hydrocarbon oils, both light and heavy, either alone or in combination with oils of a different nature, while possessing some of the charac teristics of glycerine, produce very unsatisfactory results, so far as my observation and experience have extended.
The method of using my improved compound will readily suggest itself to any dentist without explicit instructions in that respect. It may be conveyed to the cavity as often as required before and during the operation of excavating by means of a small piece of punk or cotton saturated in the solution and held in any proper implement, or it may be applied in any other manner most convenient, using about one drop at each application. When prepared in accordance with the formula the compound is too strong for use in making the first applications to the tooth, and should be diluted with distilled water until reduced to the proper strength to be borne by the patient, the undiluted compound being used for the later and final applications.
It will be obvious that the compound may In a dental compound for preventing pain be employed to prevent pain not only in prein excavating and preparing teeth for filling, paring the cavities and filling the same, but in the combination of glycerine, tannic acid, and numerous other operations on the teeth; also, chloral, substantially as set forth and speci- 5 that on account of its transparency it will not fied.
interfere with a free inspection of the work being done-a very essential feature in an arti- HERBERT ENOS BENNETT cle of this character. Witnesses:
Having thus explained my invention, what SoLoN S. ROBIE,
10 I claim is-- O. A. SHAW.
Publications (1)
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US232807A true US232807A (en) | 1880-10-05 |
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US232807D Expired - Lifetime US232807A (en) | Herbert e |
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US20040028750A1 (en) * | 1998-04-24 | 2004-02-12 | Cell Therapeutics, Inc. | Arsenic sulfide compounds and derivatives thereof for the treatment of malignancies |
US6723351B2 (en) | 1997-11-10 | 2004-04-20 | Memorial Sloan-Kettering Cancer Center | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
US20040096518A1 (en) * | 1997-10-15 | 2004-05-20 | Polarx Biopharmaceuticals, Inc. | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds |
US20090176876A1 (en) * | 2008-01-04 | 2009-07-09 | Jr Chem, Llc | Compositions, kits and regimens for the treatment of skin, especially decolletage |
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US7927614B2 (en) | 2006-02-03 | 2011-04-19 | Jr Chem, Llc | Anti-aging treatment using copper and zinc compositions |
US8952057B2 (en) | 2011-01-11 | 2015-02-10 | Jr Chem, Llc | Compositions for anorectal use and methods for treating anorectal disorders |
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0
- US US232807D patent/US232807A/en not_active Expired - Lifetime
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US20040161475A1 (en) * | 1997-10-15 | 2004-08-19 | Polarx Biopharmaceuticals, Inc. | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds |
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