US20170281358A1 - Expandable fusion device for positioning between adjacent vertebral bodies - Google Patents
Expandable fusion device for positioning between adjacent vertebral bodies Download PDFInfo
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- US20170281358A1 US20170281358A1 US15/351,943 US201615351943A US2017281358A1 US 20170281358 A1 US20170281358 A1 US 20170281358A1 US 201615351943 A US201615351943 A US 201615351943A US 2017281358 A1 US2017281358 A1 US 2017281358A1
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- expansion
- implant
- fusion device
- expandable fusion
- upper body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
- A61F2/447—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages substantially parallelepipedal, e.g. having a rectangular or trapezoidal cross-section
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2/4611—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
- A61F2/4465—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages having a circular or kidney shaped cross-section substantially perpendicular to the axis of the spine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30476—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements locked by an additional locking mechanism
- A61F2002/30507—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements locked by an additional locking mechanism using a threaded locking member, e.g. a locking screw or a set screw
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30537—Special structural features of bone or joint prostheses not otherwise provided for adjustable
- A61F2002/30556—Special structural features of bone or joint prostheses not otherwise provided for adjustable for adjusting thickness
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30904—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves serrated profile, i.e. saw-toothed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2002/4625—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use
- A61F2002/4627—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use with linear motion along or rotating motion about the instrument axis or the implantation direction, e.g. telescopic, along a guiding rod, screwing inside the instrument
Definitions
- This invention relates to spinal implant devices and methods for promoting fusion between adjacent vertebral bodies, and more particularly to expandable fusion devices that can be inserted between adjacent vertebral bodies to facilitate the fusion thereof.
- the human spine is a complex mechanical structure, composed of alternating bony vertebrae and fibrocartilaginous discs that are connected by strong ligaments and supported by musculature, that extends from the skull to the pelvis and provides axial support for the body.
- the vertebrae generally comprise a vertebral foramen bounded by the anterior vertebral body and the neural arch.
- the vertebral body comprises two end plates (i.e., superior and inferior) made of thin cartilage overlying a thin layer of hard cortical bone that attaches to the spongy, cancellous interior bone of the vertebral body.
- the neural arch consists of two pedicles and two lamina that are united posteriorly. The spinous and transverse processes protrude from the neural arch. The superior and inferior articular facets lie at the root of the transverse processes.
- the intervertebral discs primarily serve as a mechanical cushion between adjacent vertebral segments of the spinal column and generally comprise two basic components: the annulus fibrosis and the nucleus pulposus.
- the annulus fibrosis forms the outer perimeter of the disc and is a tough ring that binds adjacent vertebrae together.
- the nucleus pulposus fills the interior of the disc and carries load.
- the spine as a whole is a highly flexible structure capable of a high degree of curvature and twist in nearly every direction.
- genetic or developmental irregularities, trauma, chronic stress, and degenerative wear can result in spinal pathologies for which surgical intervention may be necessary.
- intervertebral fusion In some cases it is desired to fuse the adjacent vertebrae together after removal of the disc. Such a procedure is sometimes referred to as “intervertebral fusion” or “interbody fusion”.
- intervertebral fusion many techniques and instruments have been devised to perform intervertebral fusion. There is common agreement that the strongest intervertebral fusion is interbody fusion between the lumbar bodies, which may be augmented by a posterior or facet fusion. In cases of intervertebral fusion, either structural bone, or a rigid interbody fusion “cage” typically filled with morselized bone, is placed centrally within the space where the spinal disc once resided. Multiple bony grafts or cages may be used within that space. Furthermore, multiple surgical approaches may be utilized, including anterior, posterior, or lateral surgical approaches.
- Such practices are characterized by certain disadvantages, including the need to distract the disc space in order to implant the fusion device and thereby restore the diseased disc space to its normal or healthy height.
- it can be difficult to distract the adjacent vertebral bodies sufficiently to easily insert the fusion device between adjacent vertebral bodies.
- it is often necessary to drive the fusion device into the space between the vertebral bodies using impaction with a mallet and the application of significant force.
- the use of such impaction and force increases the risk of damage to local soft tissue such as blood vessels and the surrounding nerves, and can lead to suboptimal placement and/or failure of the insertion instrumentation.
- the use of such impaction and force can damage or compromise the vertebral endplates, resulting in eventual failure and subsidence of the fusion device into the vertebral bodies and hence loss of disc height.
- a fusion device that can be placed between adjacent vertebral bodies at minimal height and, thereafter, be variably adjusted with minimal force application to the preferred height for an individual patient. Furthermore, it is desirable that the expandable fusion device be maintained in a closed (i.e., unexpanded) position during insertion and handling, and that it be rigidly attachable to a holder so as to facilitate maximum control by the surgeon during insertion and deployment.
- an expandable fusion device that can be placed between adjacent vertebral bodies at minimal height and, thereafter, be variably adjusted with minimal force application to the preferred height for an individual patient.
- an expandable PLIF (Posterior Lumbar Interbody Fusion) device or an expandable TLIF (Transforaminal Lumbar Interbody Fusion) device is disclosed.
- the expandable fusion device generally includes: a cage, superior and lower bodys, and an expansion mechanism with opposing proximal and second expansion members.
- the application of torque to the expansion mechanism in one direction causes the proximal and second expansion members to separate, whereby to move the superior and lower bodies away from one another and hence increase the height of expandable fusion device 5 .
- the application of torque to the expansion mechanism in the opposite direction causes the proximal and second expansion members to approach one another, whereby to move the superior and lower bodys toward one another and hence decrease the height of the expandable fusion device.
- FIG. 1 may depict a curved or lordotic superior and lower bodys to match the angle of the disc space; (ii) mismatched proximal and second expansion members, such that the anterior portion of the expandable fusion device opens more than the posterior portion of the expandable fusion device, thereby resulting in a fusion device that increases in both height and lordosis; (iii) dual or multiple expansion mechanisms for anterior spinal approaches; (iv) a curved or flexible holder for the expandable fusion device for oblique access approaches; and (v) additional angled components (i.e., intermediate the aforementioned proximal and second expansion members) for longer expandable fusion devices.
- additional angled components i.e., intermediate the aforementioned proximal and second expansion members
- system and/or method may include an intervertebral implant for a human spine including an upper body, a lower body, first and second expansion members, and an expansion mechanism.
- the upper body may include an inferior surface and a superior surface.
- the superior surface of the upper body may function to engage a first vertebra of the human spine.
- the lower body may include a superior surface and an inferior surface.
- the inferior surface of the lower body may function to engage a second vertebra of the human spine.
- the first expansion member may include at least a first angled portion.
- the first angled portion may be positionable, during use, between the inferior surface of the upper body and the superior surface of the lower body. At least the first angled portion may be oriented towards a first end of the intervertebral implant.
- the second expansion member may include at least a second angled portion positionable, during use, between the inferior surface of the upper body and the superior surface of the lower body. At least the second angled portion may be oriented towards a second end of the intervertebral implant. At least the second angled portion may be oriented in an opposing direction relative to at least the first angled portion.
- An expansion mechanism may convey, during use, the first and second angled portions in opposing directions increasing a separation distance between the upper body and the lower body.
- the first and/or second angled portion may include a wedge-shaped portion.
- the expansion mechanism may include a threaded elongated member.
- the threaded elongated member may include a proximally threaded portion.
- the first expansion member may include a threaded opening which the threaded portion of the elongated member engages, during use.
- a distal end of the elongated member engages, during use, a proximal end of the second expansion member.
- the distal end may engage a recess in the second expansion member and rotates freely within it.
- the expansion mechanism may include a first elongated member and a second elongated member.
- the first elongated member may include a proximally threaded portion.
- the first expansion member may include a threaded opening which the threaded portion of the first elongated member engages, during use.
- the second elongated member may be positionable, during use, in an opening in the second expansion member. A distal end of the first elongated member may engage, during use, a proximal end of the second elongated member.
- a distal end of the first elongated member may engage, during use, a proximal end of the second elongated member such that the distal end of the first elongated member is positioned in the opening in the second expansion member.
- the expansion member may include a locking member.
- the locking member may be positionable in the second expansion member such that the distal end of the first elongated member is inhibited, during use, from removal from the opening in the second expansion member.
- the intervertebral implant may include a cage.
- the cage may form a perimeter around the intervertebral implant in which at least portions of the upper body, the lower body, the first expansion member, the second expansion member, and the expansion mechanism are positioned, during use, in the cage.
- the cage may include one or more openings along the perimeter to allow graft material to be positioned during use.
- a lateral cross section of a perimeter of the intervertebral implant may include a curved shape such that at least a first portion of the perimeter is substantially convex and at least a second portion of the perimeter is substantially concave, wherein the second portion is substantially opposite the first portion.
- the upper body and/or the lower body may include an opening wherein graft material is positionable during use.
- the upper body and/or the lower body may include an opening which increases in size as the first and second angled portions are conveyed in opposing directions.
- the superior surface of the upper body and/or the inferior surface of the lower body may include protrusions (e.g., teeth).
- the protrusions may promote, during use, retention of the implant between the first vertebra and the second vertebra after insertion.
- FIG. 1 depicts a schematic side view showing an expandable fusion device formed in accordance with the present invention, with the expandable fusion device being disposed between adjacent vertebral bodies.
- FIG. 2 depicts a schematic exploded view of an expandable fusion device.
- FIG. 3 depicts a schematic front perspective view of an expandable fusion device, with the expandable fusion device being shown in an unexpanded position.
- FIG. 4 depicts a schematic front perspective view of an expandable fusion device, with the expandable fusion device being shown in an expanded position.
- FIG. 5 depicts a schematic rear perspective view of an expandable fusion device, with the expandable fusion device being shown in an unexpanded position.
- FIG. 6 depicts a schematic rear perspective view of an expandable fusion device, with the expandable fusion device being shown in an expanded position.
- FIG. 7 is a schematic side view of an expandable fusion device, with the expandable fusion device being shown in an unexpanded position.
- FIG. 8 depicts a schematic side view of an expandable fusion device, with the expandable fusion device being shown in an expanded position.
- FIG. 9 depicts a schematic top view of an expandable fusion device.
- FIG. 10 depicts a schematic side cross-sectional view of an expandable fusion device, with the expandable fusion device being shown in an unexpanded position.
- FIG. 11 depicts a schematic side cross-sectional view of an expandable fusion device, with the expandable fusion device being shown in an expanded position.
- FIG. 12 depicts a schematic perspective cross-sectional view of an expandable fusion device, with the expandable fusion device being shown in an unexpanded condition.
- FIG. 13 depicts a schematic perspective view of a lower body.
- FIG. 14 depicts a schematic perspective cross-sectional view of a lower body.
- FIG. 15 depicts a schematic perspective cross-sectional view of an upper body.
- FIG. 16 depicts a schematic right side perspective view of the proximal and second expansion members.
- FIG. 17 depicts a schematic left side perspective view of the proximal and second expansion members.
- FIG. 18 depicts a schematic view showing insertion instruments for use with an expandable fusion device.
- FIG. 19 depicts a schematic transparent side view of an expandable fusion device.
- FIG. 20 depicts a schematic exploded view of an expandable fusion device.
- FIG. 21 depicts a schematic cross-sectional view of a curved expandable fusion device in an unexpanded state.
- FIG. 22 depicts a schematic cross-sectional view of a curved expandable fusion device in an expanded state.
- FIG. 23 depicts a schematic view of a curved expandable fusion device as the device is being inserted between two adjacent vertebrae.
- FIG. 24 depicts a schematic view showing insertion instruments for use with an expandable fusion device.
- FIG. 25 depicts a schematic view showing a distal end of an insertion instrument for use with an expandable fusion device.
- FIG. 26 depicts a schematic view showing a proximal end of an insertion instrument for use with an expandable fusion device.
- FIG. 27 depicts a schematic view of a disposable expandable fusion implant insertion device.
- FIG. 28 depicts a schematic transparent view of a disposable expandable fusion implant insertion device.
- FIG. 29 depicts a schematic perspective view of an expandable fusion implant in an expanded state wherein an upper body portion of the implant is depicted as transparent.
- FIG. 30 depicts a schematic perspective view of an expandable fusion implant in an expanded state wherein an upper body portion of the implant is depicted as transparent.
- FIG. 31 depicts a schematic perspective view of an expandable fusion implant in a contracted state.
- FIG. 32 depicts a schematic perspective view of an expandable fusion implant in a contracted state coupled to an insertion instrument with portions of the insertion instruments depicted as transparent. An upper body of the implant is not depicted and a second expandable member is depicted as transparent.
- FIG. 33 depicts a schematic view of an insertion instrument with an expandable fusion device.
- FIG. 34 depicts a schematic view of a distal end of an insertion instrument with an expandable fusion device.
- FIG. 35 depicts a schematic view of a distal end of an insertion instrument with an expandable fusion device with a portion of the insertion instrument removed for clarity.
- FIG. 36 depicts a schematic view of a distal end of an insertion instrument with an expandable fusion device with a portion of the insertion instrument removed for clarity.
- FIG. 37 depicts a schematic perspective view of an expandable fusion implant in a contracted state. At least an upper body and a cage of the implant is not depicted.
- first, second, third, and so forth as used herein are used as labels for nouns that they precede, and do not imply any type of ordering (e.g., spatial, temporal, logical, etc.) unless such an ordering is otherwise explicitly indicated.
- a “third die electrically connected to the module substrate” does not preclude scenarios in which a “fourth die electrically connected to the module substrate” is connected prior to the third die, unless otherwise specified.
- a “second” feature does not require that a “first” feature be implemented prior to the “second” feature, unless otherwise specified.
- Various components may be described as “configured to” perform a task or tasks.
- “configured to” is a broad recitation generally meaning “having structure that” performs the task or tasks during operation. As such, the component can be configured to perform the task even when the component is not currently performing that task (e.g., a set of electrical conductors may be configured to electrically connect a module to another module, even when the two modules are not connected).
- “configured to” may be a broad recitation of structure generally meaning “having circuitry that” performs the task or tasks during operation. As such, the component can be configured to perform the task even when the component is not currently on.
- the circuitry that forms the structure corresponding to “configured to” may include hardware circuits.
- connection generally refers to pieces which may be joined or linked together.
- Coupled generally refers to pieces which may be used operatively with each other, or joined or linked together, with or without one or more intervening members.
- intervertebral implant 5 (e.g., expandable fusion device) formed in accordance with the present invention, with the intervertebral implant 5 being shown disposed between a superior vertebral body 10 and an inferior vertebral body 15 .
- intervertebral implant 5 may be inserted between superior vertebral body 10 and inferior vertebral body 15 while the intervertebral implant is in a contracted condition (e.g., as depicted in FIGS. 3 and 5 ), and thereafter expanded (e.g., as depicted in FIGS. 4 and 6 ) as necessary so as to span and engage the endplate 20 of superior vertebral body 10 and the endplate 25 of inferior vertebral body 15 , whereby to support superior vertebral body 10 and inferior vertebral body 15 relative to one another.
- a contracted condition e.g., as depicted in FIGS. 3 and 5
- expanded e.g., as depicted in FIGS. 4 and 6
- intervertebral implant 5 (e.g., as depicted in FIG. 2 ) generally includes a cage 30 , an upper body 35 , a lower body 40 , an expansion mechanism 45 , a first expansion member 50 (e.g., positioned proximally) and a second expansion member 55 (e.g., positioned distally).
- first expansion member 50 e.g., positioned proximally
- second expansion member 55 e.g., positioned distally
- first expansion member 50 and second expansion member 55 draw towards one another, whereby to move upper body 35 and lower body 40 toward one another and hence decrease the height of intervertebral implant 5 .
- the mechanism may be reversed with, for example, the expansion members moving towards one another during expansion (although the opening for biological material might be reduced in such an embodiment).
- a cage 30 includes a generally rectangular structure 60 having a hollow interior 65 , a distal opening 70 and a proximal opening 75 .
- Two seats 80 are formed in the opposing side surfaces of cage 30 .
- Upper body 35 generally includes a block 85 having an inferior recess 90 , and a textured superior surface 95 , and a pair of inclined camming surfaces 100 , 105 .
- Camming surfaces 100 , 105 of upper body 35 may be inclined in opposite directions (e.g., as depicted in FIG. 15 ).
- Lower body 40 generally includes a block 110 having a superior recess 115 , a textured inferior surface 120 and a pair of inclined camming surfaces 125 , 130 .
- Camming surfaces 125 , 130 of lower body 40 may be inclined in opposite directions (e.g., as depicted in FIGS. 13-14 ).
- the camming surface 100 of upper body 35 and the camming surfaces 130 of lower body 40 extend parallel to one another, and the camming surfaces 105 of upper body 35 and the camming surface 125 of lower body 40 extend parallel to one another.
- Expansion mechanism 45 generally includes an elongated shaft 135 having an annular shoulder 140 formed intermediate its length. A groove 145 is formed distal to annular shoulder 140 . Screw threads 147 are formed on the outer surface of elongated shaft 135 proximal to annular shoulder 140 . A noncircular bore 150 opens on the proximal end of expansion mechanism 45 and extends distally thereof.
- Superior and/or inferior surfaces of the implant may include various features to facilitate engagement of the surfaces with endplates of adjacent vertebrae.
- the implant may include a plurality of surface deformations positioned on the inferior surface and/or the superior surface. Surface deformations may include protrusions.
- superior surface of the implant 5 may include protrusions (e.g., teeth) 154 extending there from. During use, teeth 154 may extend/penetrate into adjacent boney structure of the upper and lower adjacent vertebrae. Such penetration may help to fix a position of the implant 5 relative to the vertebrae.
- Fixing or otherwise stabilizing the implant may reduce the likelihood of implant 5 being expelled from within the intervertebral space, and may promote bone attachment to and through implant 5 .
- various spray coatings may be applied to one or more exterior surfaces to, for example, enhance fixation with adjacent bone surfaces.
- protrusions 154 may include directional teeth that facilitate movement of the members in a first direction, but inhibit movement of the members in a second opposing direction.
- teeth 154 include a ramped leading surface 154 a and a substantially vertical trailing edge 154 b (e.g., depicted in FIGS. 7-8 ).
- forward advancement of the members may be facilitated as boney structure of the vertebrae slides over ramped leading surface 154 a of teeth 154 and backward advancement may be inhibited by substantially vertical trailing edge 154 b hooking into or otherwise engaging the boney structure of the vertebrae.
- one or more portions of the implant may include one or more markers. Markers may be used to assess a position of one or more portions of the implant during implantation in a subject. A portion of the implant may include none, one or multiple markers. Markers may provide radiographic opacity. Markers may be biocompatible. Markers may be of any size or shape. In some embodiments, a system may have multiple markers with different shapes in order to more easily identify different portions or directions of the system and/or an orientation of one or more portions of the implant. In some embodiments, one or more markers may be formed from gold or tantalum.
- the implant 5 may include an opening 152 a extending through the implant (e.g., depicted in FIGS. 9-12 ).
- the opening may hold biological material during use.
- opening 152 a may be filled with a substance/material to facilitate bone growth/fusion.
- the opening may facilitate a column of bone growth between the adjacent vertebrae through the opening 152 a .
- an opening e.g., opening 152 a
- the opening may increase in size as the first and second expansion members move away from each other as the implant is deployed.
- implant 5 may include one or more second openings 152 b (e.g., depicted in FIG. 20 ).
- the second openings may be positioned on either side of cage 30 .
- the openings may facilitate insertion of biological material.
- additional openings 152 b may facilitate in packing of biological material (e.g., bone graft).
- the openings may be initially at least partially blocked by the first and second expansion members and/or the upper and lower bodies, as the implant is expanded the second openings may open up.
- implant 5 may include a proximal opening 152 c (e.g., depicted in FIG. 29 ).
- a proximal opening may allow biological material to be positioned in the interior of the implant after the implant has been positioned.
- the proximal opening may facilitate insertion of biological material after insertion of the implant.
- a proximal opening in the implant may necessitate positioning the expansion mechanism (e.g., elongated members 45 a - b as depicted in FIGS. 30-31 ) off center in order to allow for creating a large enough proximal opening.
- the first expansion member 50 may be modified to allow biological material inserted through the proximal opening to pass beyond the first expansion member into the space between the first and the second expansion member 50 , 55 .
- the first expansion member may include an opening 156 and/or shaped to create an opening in combination with an interior surface of the cage 30 (e.g., as depicted in FIGS. 32 and 37 ).
- a distal end 235 of the elongated member engages, during use, a proximal end of the second expansion member 55 .
- the distal end of the elongated member abuts a proximal end of the second expansion member as opposed to extending through an opening in the second expansion member.
- the distal end may engage a recess 240 in the second expansion member 55 (e.g., as depicted in FIG. 19 ).
- a recess may include a shallow opening. The distal end may turn freely in the recess.
- the recess may assist in centering and/or positioning the distal end of the elongated member 45 such that the distal end is inhibited from misaligning and/or disengaging from the second expansion member.
- the implant 5 may include a second elongated member 45 b .
- the second elongated member 45 b may be positioned in the second expansion member 55 and opening 70 such that the second elongated member keeps the second expansion member centered.
- the expansion mechanism may include a first elongated member 45 a and a second elongated member 45 b (e.g., as depicted in FIG. 20 ).
- the first elongated member 45 a may include a proximally threaded portion 147 .
- the first expansion member 50 may include a threaded opening 180 which the threaded portion of the first elongated member engages, during use.
- the second elongated member 45 b may be positionable, during use, in an opening 210 in the second expansion member 55 .
- a distal end 245 of the first elongated member 45 a may engage, during use, a proximal end 250 of the second elongated member 45 b .
- a distal end of the first elongated member may engage, during use, a proximal end of the second elongated member such that the distal end of the first elongated member is positioned in the opening in the second expansion member.
- the distal end of the first elongated member may turn freely in the opening in the second expansion member.
- the second elongated member may function to keep the second expansion member 55 central in the body of the implant.
- the second elongated member may be essentially non-rotating relative to the first elongated member.
- the separation between the expansion members is thus equal to just one pitch of the thread per rotation, or 1 ⁇ 2 pitch of movement relative to the endplate (upper & lower body) each.
- Embodiments discussed herein would have twice the separation force relative to a turnbuckle thread configured with opposing expansion members (or even with expansion members moving in the same direction) because they separate/collapse at a rate of 2 pitches per rotation and thus have twice the motion relative to the endplates.
- a size of the expansion member may be reduced to get the same force at a lower torque because passive rotation within one of the expansion members is more efficient.
- One may reduce the angle of the ramp or have a single ramp, but you would need considerably more travel to achieve the same height and would run into length limitations. Many embodiments described herein increase rotations not travel.
- Forming the expansion mechanism from two elongated members as opposed to a single elongated member has several advantages. For example when retracting upper body 35 and lower body 40 from an engaged position to an unengaged position, torque applied to the expansion mechanism during retraction may lead to failure of the expansion mechanism when the expansion mechanism includes a single elongated member. When the expansion mechanism includes two elongated members, failure of the expansion mechanism when counter (retracting) torque is applied is inhibited.
- one or more of the expansion members may include a locking member 255 .
- the locking member may be positionable in the second expansion member 55 such that the second elongated member is inhibited, during use, from removal from the opening in the second expansion member.
- the locking member may include a pin.
- the pin may be positioned in an opening in the second expansion member.
- the locking member may engage a recess 260 in the second elongated member.
- the recess may circumscribe the circumference of the second elongated member such that the second elongated member does not have to be oriented in a particular direction relative to the second elongated member.
- the locking member may be used in combination with the single elongated member (e.g., snap ring 215 as depicted in FIG. 2 ).
- first expansion member 50 includes a generally wedge-shaped body 155 having a superior camming surface 160 , an inferior cam surface 165 , a pair of superior fingers 170 and a pair of inferior fingers 175 (e.g., as depicted in FIG. 16 ).
- superior camming surface 160 of first expansion member 50 extends parallel to camming surface 100 of upper body 35
- inferior camming surface 165 of first expansion member 50 extends parallel to camming surface 125 of lower body 40 . In lordotic embodiments these surfaces may only be parallel in the open position. They are not parallel when closed.
- First expansion member 50 may include a threaded bore 180 extending there through. Threaded bore 180 is sized to be threadingly engaged by screw threads 147 on elongated shaft 135 .
- second expansion member 55 includes a generally wedge-shaped body 185 having a superior camming surface 190 , an inferior camming surface 195 , a pair of superior fingers 200 and a pair of inferior fingers 205 (e.g., as depicted in FIGS. 16-17 ).
- superior camming surface 190 of second expansion member 55 extends parallel to camming surface 105 of upper body 35
- inferior camming surface 195 of second expansion member 55 extends parallel to camming surface 130 of lower body 40 . In lordotic embodiments these surfaces may only be parallel in the open position. They are not parallel when closed.
- Second expansion member 55 may include a smooth bore 210 extending there through. Smooth bore 210 may be sized to receive the portion of expansion mechanism 45 distal to annular shoulder 140 .
- Camming surfaces of the upper/lower bodies and the expansion members may be substantially flat as depicted in some of the attached FIGS. In some embodiments, at least some of the camming surfaces may be curved. Complementary camming surfaces may be complementarily shaped. Complementary camming surfaces may not be complementarily shaped.
- intervertebral implant 5 may be assembled so that expansion mechanism 45 extends through proximal opening 75 in cage 30 (without engaging proximal opening 75 in cage 30 ), and first expansion member 50 and second expansion member 55 are disposed on shaft 135 of expansion mechanism 45 within the hollow interior 65 of cage 30 . More particularly, first expansion member 50 may be mounted on elongated shaft 135 of expansion mechanism 45 so that screw threads 147 are threadingly received in threaded bore 180 of first expansion member 50 , and second expansion member 55 is mounted on elongated shaft 135 of expansion mechanism 45 so that second expansion member 55 is captured on elongated shaft 135 between annular shoulder 140 and a snap ring 215 secured in groove 145 .
- upper body 35 and lower body 40 may extend into hollow interior 65 of exterior body 30 so that (i) camming surface 100 of upper body 35 rides on camming surface 160 of first expansion member 50 , (ii) camming surface 105 of upper body 35 rides on camming surface 190 of second expansion member 55 , (iii) camming surface 125 of lower body 40 rides on camming surface 165 of first expansion member 50 , and (iv) camming surface 130 of lower body 40 rides on camming surface 195 of second expansion member 55 .
- the intervertebral implant 5 may include a curved cross-section.
- Straight designs are more commonly associated with PLIF (direct posterior placement in pairs), or lateral approaches (one longer device placed from the side of the spine).
- FIG. 21 is a schematic cross-sectional view of a curved expandable fusion device in an unexpanded state with a curved cross-section.
- FIG. 22 is a schematic cross-sectional view of a curved expandable fusion device in an expanded state with a curved cross-section.
- portions of the implant may be curved or angled in order to accommodate the curved cross-section of the perimeter.
- expansion members and the expansion mechanism may not require adjustments to assimilate into an implant with a curved perimeter.
- the distal end 235 of the expansion mechanism 45 a may engage a recess 240 in the second expansion member 55 as discussed herein and in the case of a curved implant the recess may adjusted to compensate for the varying angle of engagement of the distal end with the recess during expansion.
- the distal end of the expansion mechanism may be curved in order to accommodate a curved perimeter.
- FIG. 23 depicts a schematic view of a curved expandable fusion device 5 as the device is being inserted between two adjacent vertebrae.
- the implant inserter may be curved.
- the expansion mechanism may have a flexible shaft to allow rotation within the curve.
- an implant system may include an implant insertion device 300 .
- FIG. 18 shows a handle 215 , a holder 220 and an engaging member 225 which may be used to manipulate and deploy intervertebral implant 5 .
- handle 215 includes two extensions 230 for positioning in seats 80 (e.g., as depicted in FIGS. 3-6 ) of intervertebral implant 5 .
- Holder 220 may be positionable in handle 215 and threadingly engages the distal end of expansion mechanism 45 , whereby to releasably secure intervertebral implant 5 to handle 215 .
- Engaging member 225 may be positionable in holder 220 and into bore 150 in expansion mechanism 45 , whereby to permit the user to turn expansion mechanism 45 and hence adjust the height of the intervertebral implant 5 .
- Engaging member 225 may include engaging head 226 which engages bore 150 .
- Engaging head 226 may include a complementary shape to bore 150 such that as the head turns the expansion member 45 turns.
- an implant system may include an implant insertion device 300 .
- FIGS. 24-26 depict a schematic view showing insertion instruments 300 for use with an expandable fusion device.
- FIGS. 24-26 depict a handle 215 , a holder 220 and an engaging member 225 which may be used to manipulate and deploy intervertebral implant 5 .
- handle 215 includes two extensions 230 for positioning in seats 80 (e.g., as depicted in FIGS. 24-25 ) of intervertebral implant 5 .
- Engaging member 225 may be positionable in holder 220 and into bore 150 in expansion mechanism 45 , whereby to permit the user to turn expansion mechanism 45 and hence adjust the height of the intervertebral implant 5 .
- Engaging member 225 may include engaging head 226 which engages bore 150 .
- Engaging head 226 may include a complementary shape to bore 150 such that as the head turns the expansion member 45 turns.
- the insertion instrument 300 may include a grip 280 coupled to engaging member 225 .
- engaging member 225 may include a threaded proximal portion 285 . The threaded portion 285 may function to assist in controlling longitudinal movement of the engaging member and therefore expansion of the implant.
- an insertion device may be disposable.
- FIGS. 27-28 depict a schematic view of a disposable expandable fusion implant insertion device 300 .
- a disposable insertion device may be packaged with an implant.
- the insertion device may allow bone graft to be packed after insertion.
- the “disposable” option may allow the holder to act as an internal funnel which would make cleaning difficult, but a “durable version” remains an option.
- engaging member 225 may be used to pack biological material into the implant through holder 220 .
- a separate packing instrument (not depicted) may be used to insert biological material.
- FIGS. 32-36 depict a schematic view showing insertion instruments 300 for use with an expandable fusion device.
- FIGS. 32-36 depict a handle 215 , a holder 220 and an engaging member 225 which may be used to manipulate and deploy intervertebral implant 5 .
- handle 215 includes two extensions 230 for positioning in seats 80 (e.g., as depicted in FIGS. 24-25 ) of intervertebral implant 5 .
- the extensions may be spring loaded (e.g., using springs, forming at least a portion of the extensions from an at least slightly flexible material, etc.) such that they are biased to be positioned such that they apply pressure to the seats of the implant during use.
- a mechanism may be employed to engage/release the extensions from the implant.
- the insertion instrument may include at least two holders 220 which couple to opposing sides (e.g., the inferior and superior surfaces of the implant) of the implant during use.
- the holders may be spring loaded (e.g., using springs, forming at least a portion of the holders from an at least slightly flexible material, etc.) such that they are biased to be positioned such that they apply pressure to the surfaces of the implant during use.
- a mechanism may be employed to engage/release the holders from the implant.
- the holders may include a curved edge or lip which curve towards one another. The curved edge may engage an appropriately shaped portion of the proximal end of the implant.
- Engaging member 225 may be positionable in handle 215 and into bore 150 in expansion mechanism 45 , whereby to permit the user to turn expansion mechanism 45 and hence adjust the height of the intervertebral implant 5 .
- Engaging member 225 may include engaging head 226 which engages bore 150 .
- Engaging head 226 may include a complementary shape to bore 150 such that as the head turns the expansion member 45 turns.
- the insertion instrument 300 may include a grip 280 coupled to engaging member 225 .
Abstract
In some embodiments, system and/or method may include an intervertebral implant for a human spine including an upper body, a lower body, first and second expansion members, and an expansion mechanism. A superior surface of the upper body may function to engage a first vertebra of the human spine. An inferior surface of the lower body may function to engage a second vertebra of the human spine. The first expansion member may include at least a first angled portion positionable, during use, between the upper body and the lower body. The second expansion member may include at least a second angled portion positionable, during use, between the upper body and the lower body. An expansion mechanism may convey, during use, the first and second angled portions in opposing directions increasing a separation distance between the upper body and the lower body.
Description
- This application claims priority to U.S. Provisional Patent Application No. 61/766,982 entitled “EXPANDABLE FUSION DEVICE FOR POSITIONING BETWEEN ADJACENT VERTEBRAL BODIES” filed on Feb. 20, 2013, which is incorporated by reference herein.
- This invention relates to spinal implant devices and methods for promoting fusion between adjacent vertebral bodies, and more particularly to expandable fusion devices that can be inserted between adjacent vertebral bodies to facilitate the fusion thereof.
- The human spine is a complex mechanical structure, composed of alternating bony vertebrae and fibrocartilaginous discs that are connected by strong ligaments and supported by musculature, that extends from the skull to the pelvis and provides axial support for the body.
- The vertebrae generally comprise a vertebral foramen bounded by the anterior vertebral body and the neural arch. The vertebral body comprises two end plates (i.e., superior and inferior) made of thin cartilage overlying a thin layer of hard cortical bone that attaches to the spongy, cancellous interior bone of the vertebral body. The neural arch consists of two pedicles and two lamina that are united posteriorly. The spinous and transverse processes protrude from the neural arch. The superior and inferior articular facets lie at the root of the transverse processes.
- The intervertebral discs primarily serve as a mechanical cushion between adjacent vertebral segments of the spinal column and generally comprise two basic components: the annulus fibrosis and the nucleus pulposus. The annulus fibrosis forms the outer perimeter of the disc and is a tough ring that binds adjacent vertebrae together. The nucleus pulposus fills the interior of the disc and carries load.
- The spine as a whole is a highly flexible structure capable of a high degree of curvature and twist in nearly every direction. However, genetic or developmental irregularities, trauma, chronic stress, and degenerative wear can result in spinal pathologies for which surgical intervention may be necessary.
- It is common practice to remove a spinal disc in cases of spinal disc deterioration, disease or spinal injury. More particularly, the discs sometimes become diseased or damaged such that the height of the disc is reduced, which causes the annulus to buckle in areas where the laminated plies are loosely bonded. As the overlapping laminated plies of the annulus begin to buckle and separate, circumferential and/or radial annular tears may occur, allowing nucleus material to escape or form a bulge in the annulus. Such disruption to the natural intervertebral separation and the resulting herniation produces pain, which can be alleviated by removal of the disc and restoration of the natural separation distance. In cases of chronic back or leg pain resulting from a degenerated or herniated disc, removal of the disc can become the desired course of treatment.
- In some cases it is desired to fuse the adjacent vertebrae together after removal of the disc. Such a procedure is sometimes referred to as “intervertebral fusion” or “interbody fusion”.
- Many techniques and instruments have been devised to perform intervertebral fusion. There is common agreement that the strongest intervertebral fusion is interbody fusion between the lumbar bodies, which may be augmented by a posterior or facet fusion. In cases of intervertebral fusion, either structural bone, or a rigid interbody fusion “cage” typically filled with morselized bone, is placed centrally within the space where the spinal disc once resided. Multiple bony grafts or cages may be used within that space. Furthermore, multiple surgical approaches may be utilized, including anterior, posterior, or lateral surgical approaches.
- Such practices are characterized by certain disadvantages, including the need to distract the disc space in order to implant the fusion device and thereby restore the diseased disc space to its normal or healthy height. However, it can be difficult to distract the adjacent vertebral bodies sufficiently to easily insert the fusion device between adjacent vertebral bodies. As a result, it is often necessary to drive the fusion device into the space between the vertebral bodies using impaction with a mallet and the application of significant force. The use of such impaction and force increases the risk of damage to local soft tissue such as blood vessels and the surrounding nerves, and can lead to suboptimal placement and/or failure of the insertion instrumentation. Furthermore, the use of such impaction and force can damage or compromise the vertebral endplates, resulting in eventual failure and subsidence of the fusion device into the vertebral bodies and hence loss of disc height.
- Therefore, there is a need for a fusion device that can be placed between adjacent vertebral bodies at minimal height and, thereafter, be variably adjusted with minimal force application to the preferred height for an individual patient. Furthermore, it is desirable that the expandable fusion device be maintained in a closed (i.e., unexpanded) position during insertion and handling, and that it be rigidly attachable to a holder so as to facilitate maximum control by the surgeon during insertion and deployment.
- Accordingly, there is now provided an expandable fusion device that can be placed between adjacent vertebral bodies at minimal height and, thereafter, be variably adjusted with minimal force application to the preferred height for an individual patient. In one embodiment, an expandable PLIF (Posterior Lumbar Interbody Fusion) device or an expandable TLIF (Transforaminal Lumbar Interbody Fusion) device, is disclosed. The expandable fusion device generally includes: a cage, superior and lower bodys, and an expansion mechanism with opposing proximal and second expansion members. The application of torque to the expansion mechanism in one direction causes the proximal and second expansion members to separate, whereby to move the superior and lower bodies away from one another and hence increase the height of
expandable fusion device 5. The application of torque to the expansion mechanism in the opposite direction causes the proximal and second expansion members to approach one another, whereby to move the superior and lower bodys toward one another and hence decrease the height of the expandable fusion device. - Further embodiments may include: (i) angled or lordotic superior and lower bodys to match the angle of the disc space; (ii) mismatched proximal and second expansion members, such that the anterior portion of the expandable fusion device opens more than the posterior portion of the expandable fusion device, thereby resulting in a fusion device that increases in both height and lordosis; (iii) dual or multiple expansion mechanisms for anterior spinal approaches; (iv) a curved or flexible holder for the expandable fusion device for oblique access approaches; and (v) additional angled components (i.e., intermediate the aforementioned proximal and second expansion members) for longer expandable fusion devices.
- In some embodiments, system and/or method may include an intervertebral implant for a human spine including an upper body, a lower body, first and second expansion members, and an expansion mechanism. The upper body may include an inferior surface and a superior surface. The superior surface of the upper body may function to engage a first vertebra of the human spine. The lower body may include a superior surface and an inferior surface. The inferior surface of the lower body may function to engage a second vertebra of the human spine. The first expansion member may include at least a first angled portion. The first angled portion may be positionable, during use, between the inferior surface of the upper body and the superior surface of the lower body. At least the first angled portion may be oriented towards a first end of the intervertebral implant. The second expansion member may include at least a second angled portion positionable, during use, between the inferior surface of the upper body and the superior surface of the lower body. At least the second angled portion may be oriented towards a second end of the intervertebral implant. At least the second angled portion may be oriented in an opposing direction relative to at least the first angled portion. An expansion mechanism may convey, during use, the first and second angled portions in opposing directions increasing a separation distance between the upper body and the lower body. The first and/or second angled portion may include a wedge-shaped portion.
- In some embodiments, the expansion mechanism may include a threaded elongated member. The threaded elongated member may include a proximally threaded portion. The first expansion member may include a threaded opening which the threaded portion of the elongated member engages, during use.
- In some embodiments, a distal end of the elongated member engages, during use, a proximal end of the second expansion member. The distal end may engage a recess in the second expansion member and rotates freely within it.
- In some embodiments, the expansion mechanism may include a first elongated member and a second elongated member. The first elongated member may include a proximally threaded portion. The first expansion member may include a threaded opening which the threaded portion of the first elongated member engages, during use. The second elongated member may be positionable, during use, in an opening in the second expansion member. A distal end of the first elongated member may engage, during use, a proximal end of the second elongated member. In some embodiments, a distal end of the first elongated member may engage, during use, a proximal end of the second elongated member such that the distal end of the first elongated member is positioned in the opening in the second expansion member.
- In some embodiments, the expansion member may include a locking member. The locking member may be positionable in the second expansion member such that the distal end of the first elongated member is inhibited, during use, from removal from the opening in the second expansion member.
- In some embodiments, the intervertebral implant may include a cage. The cage may form a perimeter around the intervertebral implant in which at least portions of the upper body, the lower body, the first expansion member, the second expansion member, and the expansion mechanism are positioned, during use, in the cage. The cage may include one or more openings along the perimeter to allow graft material to be positioned during use.
- In some embodiments, a lateral cross section of a perimeter of the intervertebral implant may include a curved shape such that at least a first portion of the perimeter is substantially convex and at least a second portion of the perimeter is substantially concave, wherein the second portion is substantially opposite the first portion.
- In some embodiments, the upper body and/or the lower body may include an opening wherein graft material is positionable during use. The upper body and/or the lower body may include an opening which increases in size as the first and second angled portions are conveyed in opposing directions.
- In some embodiments, the superior surface of the upper body and/or the inferior surface of the lower body may include protrusions (e.g., teeth). The protrusions may promote, during use, retention of the implant between the first vertebra and the second vertebra after insertion.
- Advantages of the present invention may become apparent to those skilled in the art with the benefit of the following detailed description of the preferred embodiments and upon reference to the accompanying drawings.
-
FIG. 1 depicts a schematic side view showing an expandable fusion device formed in accordance with the present invention, with the expandable fusion device being disposed between adjacent vertebral bodies. -
FIG. 2 depicts a schematic exploded view of an expandable fusion device. -
FIG. 3 depicts a schematic front perspective view of an expandable fusion device, with the expandable fusion device being shown in an unexpanded position. -
FIG. 4 depicts a schematic front perspective view of an expandable fusion device, with the expandable fusion device being shown in an expanded position. -
FIG. 5 depicts a schematic rear perspective view of an expandable fusion device, with the expandable fusion device being shown in an unexpanded position. -
FIG. 6 depicts a schematic rear perspective view of an expandable fusion device, with the expandable fusion device being shown in an expanded position. -
FIG. 7 is a schematic side view of an expandable fusion device, with the expandable fusion device being shown in an unexpanded position. -
FIG. 8 depicts a schematic side view of an expandable fusion device, with the expandable fusion device being shown in an expanded position. -
FIG. 9 depicts a schematic top view of an expandable fusion device. -
FIG. 10 depicts a schematic side cross-sectional view of an expandable fusion device, with the expandable fusion device being shown in an unexpanded position. -
FIG. 11 depicts a schematic side cross-sectional view of an expandable fusion device, with the expandable fusion device being shown in an expanded position. -
FIG. 12 depicts a schematic perspective cross-sectional view of an expandable fusion device, with the expandable fusion device being shown in an unexpanded condition. -
FIG. 13 depicts a schematic perspective view of a lower body. -
FIG. 14 depicts a schematic perspective cross-sectional view of a lower body. -
FIG. 15 depicts a schematic perspective cross-sectional view of an upper body. -
FIG. 16 depicts a schematic right side perspective view of the proximal and second expansion members. -
FIG. 17 depicts a schematic left side perspective view of the proximal and second expansion members. -
FIG. 18 depicts a schematic view showing insertion instruments for use with an expandable fusion device. -
FIG. 19 depicts a schematic transparent side view of an expandable fusion device. -
FIG. 20 depicts a schematic exploded view of an expandable fusion device. -
FIG. 21 depicts a schematic cross-sectional view of a curved expandable fusion device in an unexpanded state. -
FIG. 22 depicts a schematic cross-sectional view of a curved expandable fusion device in an expanded state. -
FIG. 23 depicts a schematic view of a curved expandable fusion device as the device is being inserted between two adjacent vertebrae. -
FIG. 24 depicts a schematic view showing insertion instruments for use with an expandable fusion device. -
FIG. 25 depicts a schematic view showing a distal end of an insertion instrument for use with an expandable fusion device. -
FIG. 26 depicts a schematic view showing a proximal end of an insertion instrument for use with an expandable fusion device. -
FIG. 27 depicts a schematic view of a disposable expandable fusion implant insertion device. -
FIG. 28 depicts a schematic transparent view of a disposable expandable fusion implant insertion device. -
FIG. 29 depicts a schematic perspective view of an expandable fusion implant in an expanded state wherein an upper body portion of the implant is depicted as transparent. -
FIG. 30 depicts a schematic perspective view of an expandable fusion implant in an expanded state wherein an upper body portion of the implant is depicted as transparent. -
FIG. 31 depicts a schematic perspective view of an expandable fusion implant in a contracted state. -
FIG. 32 depicts a schematic perspective view of an expandable fusion implant in a contracted state coupled to an insertion instrument with portions of the insertion instruments depicted as transparent. An upper body of the implant is not depicted and a second expandable member is depicted as transparent. -
FIG. 33 depicts a schematic view of an insertion instrument with an expandable fusion device. -
FIG. 34 depicts a schematic view of a distal end of an insertion instrument with an expandable fusion device. -
FIG. 35 depicts a schematic view of a distal end of an insertion instrument with an expandable fusion device with a portion of the insertion instrument removed for clarity. -
FIG. 36 depicts a schematic view of a distal end of an insertion instrument with an expandable fusion device with a portion of the insertion instrument removed for clarity. -
FIG. 37 depicts a schematic perspective view of an expandable fusion implant in a contracted state. At least an upper body and a cage of the implant is not depicted. - While the invention is susceptible to various modifications and alternative forms, specific embodiments thereof are shown by way of example in the drawings and may herein be described in detail. The drawings may not be to scale. It should be understood, however, that the drawings and detailed description thereto are not intended to limit the invention to the particular form disclosed, but on the contrary, the intention is to cover all modifications, equivalents and alternatives falling within the spirit and scope of the present invention as defined by the appended claims.
- The headings used herein are for organizational purposes only and are not meant to be used to limit the scope of the description. As used throughout this application, the word “may” is used in a permissive sense (i.e., meaning having the potential to), rather than the mandatory sense (i.e., meaning must). The words “include,” “including,” and “includes” indicate open-ended relationships and therefore mean including, but not limited to. Similarly, the words “have,” “having,” and “has” also indicated open-ended relationships, and thus mean having, but not limited to. The terms “first,” “second,” “third,” and so forth as used herein are used as labels for nouns that they precede, and do not imply any type of ordering (e.g., spatial, temporal, logical, etc.) unless such an ordering is otherwise explicitly indicated. For example, a “third die electrically connected to the module substrate” does not preclude scenarios in which a “fourth die electrically connected to the module substrate” is connected prior to the third die, unless otherwise specified. Similarly, a “second” feature does not require that a “first” feature be implemented prior to the “second” feature, unless otherwise specified.
- Various components may be described as “configured to” perform a task or tasks. In such contexts, “configured to” is a broad recitation generally meaning “having structure that” performs the task or tasks during operation. As such, the component can be configured to perform the task even when the component is not currently performing that task (e.g., a set of electrical conductors may be configured to electrically connect a module to another module, even when the two modules are not connected). In some contexts, “configured to” may be a broad recitation of structure generally meaning “having circuitry that” performs the task or tasks during operation. As such, the component can be configured to perform the task even when the component is not currently on. In general, the circuitry that forms the structure corresponding to “configured to” may include hardware circuits.
- Various components may be described as performing a task or tasks, for convenience in the description. Such descriptions should be interpreted as including the phrase “configured to.” Reciting a component that is configured to perform one or more tasks is expressly intended not to invoke 35 U.S.C. §112, paragraph six, interpretation for that component.
- The scope of the present disclosure includes any feature or combination of features disclosed herein (either explicitly or implicitly), or any generalization thereof, whether or not it mitigates any or all of the problems addressed herein. Accordingly, new claims may be formulated during prosecution of this application (or an application claiming priority thereto) to any such combination of features. In particular, with reference to the appended claims, features from dependent claims may be combined with those of the independent claims and features from respective independent claims may be combined in any appropriate manner and not merely in the specific combinations enumerated in the appended claims.
- It is to be understood the present invention is not limited to particular devices or biological systems, which may, of course, vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments only, and is not intended to be limiting. As used in this specification and the appended claims, the singular forms “a”, “an”, and “the” include singular and plural referents unless the content clearly dictates otherwise. Thus, for example, reference to “a linker” includes one or more linkers.
- Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art.
- The term “connected” as used herein generally refers to pieces which may be joined or linked together.
- The term “coupled” as used herein generally refers to pieces which may be used operatively with each other, or joined or linked together, with or without one or more intervening members.
- The term “directly” as used herein generally refers to one structure in physical contact with another structure, or, when used in reference to a procedure, means that one process effects another process or structure without the involvement of an intermediate step or component.
- Looking first at
FIG. 1 , there is shown an intervertebral implant 5 (e.g., expandable fusion device) formed in accordance with the present invention, with theintervertebral implant 5 being shown disposed between a superiorvertebral body 10 and an inferiorvertebral body 15. As will hereinafter be discussed in further detail,intervertebral implant 5 may be inserted between superiorvertebral body 10 and inferiorvertebral body 15 while the intervertebral implant is in a contracted condition (e.g., as depicted inFIGS. 3 and 5 ), and thereafter expanded (e.g., as depicted inFIGS. 4 and 6 ) as necessary so as to span and engage theendplate 20 of superiorvertebral body 10 and theendplate 25 of inferiorvertebral body 15, whereby to support superiorvertebral body 10 and inferiorvertebral body 15 relative to one another. - In some embodiments, (e.g., as depicted in
FIG. 2 ) intervertebral implant 5 (e.g., as depicted inFIG. 2 ) generally includes acage 30, anupper body 35, alower body 40, anexpansion mechanism 45, a first expansion member 50 (e.g., positioned proximally) and a second expansion member 55 (e.g., positioned distally). As will hereinafter be discussed, the application of torque toexpansion mechanism 45 in one direction causesfirst expansion member 50 andsecond expansion member 55 to separate, whereby to moveupper body 35 andlower body 40 away from one another and hence increase the height ofintervertebral implant 5. The application of torque toexpansion mechanism 45 in the opposite direction causesfirst expansion member 50 andsecond expansion member 55 to draw towards one another, whereby to moveupper body 35 andlower body 40 toward one another and hence decrease the height ofintervertebral implant 5. In some embodiments, the mechanism may be reversed with, for example, the expansion members moving towards one another during expansion (although the opening for biological material might be reduced in such an embodiment). - Designs which may be similar but with for example expansion members conveying in the same direction may have a mechanical disadvantage relative to the embodiments described herein wherein the expansion members are conveyed in opposing directions. Expansion members which are conveyed in opposing directions may require half of the input torque to move as opposed to expansion members which are conveyed in the same direction.
- In some embodiments, a
cage 30 includes a generallyrectangular structure 60 having ahollow interior 65, adistal opening 70 and aproximal opening 75. Twoseats 80 are formed in the opposing side surfaces ofcage 30. -
Upper body 35 generally includes ablock 85 having aninferior recess 90, and a texturedsuperior surface 95, and a pair of inclined camming surfaces 100, 105. Camming surfaces 100, 105 ofupper body 35 may be inclined in opposite directions (e.g., as depicted inFIG. 15 ). -
Lower body 40 generally includes ablock 110 having asuperior recess 115, a texturedinferior surface 120 and a pair of inclined camming surfaces 125, 130. Camming surfaces 125, 130 oflower body 40 may be inclined in opposite directions (e.g., as depicted inFIGS. 13-14 ). - In some embodiments, the
camming surface 100 ofupper body 35 and the camming surfaces 130 oflower body 40 extend parallel to one another, and the camming surfaces 105 ofupper body 35 and thecamming surface 125 oflower body 40 extend parallel to one another. -
Expansion mechanism 45 generally includes anelongated shaft 135 having anannular shoulder 140 formed intermediate its length. Agroove 145 is formed distal toannular shoulder 140.Screw threads 147 are formed on the outer surface ofelongated shaft 135 proximal toannular shoulder 140. Anoncircular bore 150 opens on the proximal end ofexpansion mechanism 45 and extends distally thereof. - Superior and/or inferior surfaces of the implant (e.g., textured
superior surface 95 and textured inferior surface 120) may include various features to facilitate engagement of the surfaces with endplates of adjacent vertebrae. In some embodiments, the implant may include a plurality of surface deformations positioned on the inferior surface and/or the superior surface. Surface deformations may include protrusions. For example (e.g., depicted inFIG. 7 ) superior surface of theimplant 5 may include protrusions (e.g., teeth) 154 extending there from. During use,teeth 154 may extend/penetrate into adjacent boney structure of the upper and lower adjacent vertebrae. Such penetration may help to fix a position of theimplant 5 relative to the vertebrae. Fixing or otherwise stabilizing the implant may reduce the likelihood ofimplant 5 being expelled from within the intervertebral space, and may promote bone attachment to and throughimplant 5. In some embodiments, various spray coatings may be applied to one or more exterior surfaces to, for example, enhance fixation with adjacent bone surfaces. - In some embodiments,
protrusions 154 may include directional teeth that facilitate movement of the members in a first direction, but inhibit movement of the members in a second opposing direction. For example, in the illustrated embodiment,teeth 154 include a ramped leadingsurface 154 a and a substantiallyvertical trailing edge 154 b (e.g., depicted inFIGS. 7-8 ). Thus, forward advancement of the members may be facilitated as boney structure of the vertebrae slides over ramped leadingsurface 154 a ofteeth 154 and backward advancement may be inhibited by substantiallyvertical trailing edge 154 b hooking into or otherwise engaging the boney structure of the vertebrae. - In some embodiments, one or more portions of the implant may include one or more markers. Markers may be used to assess a position of one or more portions of the implant during implantation in a subject. A portion of the implant may include none, one or multiple markers. Markers may provide radiographic opacity. Markers may be biocompatible. Markers may be of any size or shape. In some embodiments, a system may have multiple markers with different shapes in order to more easily identify different portions or directions of the system and/or an orientation of one or more portions of the implant. In some embodiments, one or more markers may be formed from gold or tantalum.
- In some embodiments, the
implant 5 may include anopening 152 a extending through the implant (e.g., depicted inFIGS. 9-12 ). The opening may hold biological material during use. In some embodiments, opening 152 a may be filled with a substance/material to facilitate bone growth/fusion. Onceimplant 5 is implanted, the opening may facilitate a column of bone growth between the adjacent vertebrae through the opening 152 a. In some embodiments, an opening (e.g., opening 152 a) may function as a graft window containing bone chips and/or materials which facilitate tissue (e.g., bone) growth. The opening may increase in size as the first and second expansion members move away from each other as the implant is deployed. - In some embodiments,
implant 5 may include one or moresecond openings 152 b (e.g., depicted inFIG. 20 ). The second openings may be positioned on either side ofcage 30. The openings may facilitate insertion of biological material. After positioning an implant during use opening 152 a may be blocked by the vertebrae and thereforeadditional openings 152 b may facilitate in packing of biological material (e.g., bone graft). The openings may be initially at least partially blocked by the first and second expansion members and/or the upper and lower bodies, as the implant is expanded the second openings may open up. - In some embodiments,
implant 5 may include aproximal opening 152 c (e.g., depicted inFIG. 29 ). A proximal opening may allow biological material to be positioned in the interior of the implant after the implant has been positioned. The proximal opening may facilitate insertion of biological material after insertion of the implant. In some embodiments, a proximal opening in the implant may necessitate positioning the expansion mechanism (e.g., elongatedmembers 45 a-b as depicted inFIGS. 30-31 ) off center in order to allow for creating a large enough proximal opening. In some embodiments, thefirst expansion member 50 may be modified to allow biological material inserted through the proximal opening to pass beyond the first expansion member into the space between the first and thesecond expansion member opening 156 and/or shaped to create an opening in combination with an interior surface of the cage 30 (e.g., as depicted inFIGS. 32 and 37 ). - In some embodiments, a
distal end 235 of the elongated member (e.g.,expansion mechanism 45 a) engages, during use, a proximal end of thesecond expansion member 55. In such an embodiment, the distal end of the elongated member abuts a proximal end of the second expansion member as opposed to extending through an opening in the second expansion member. The distal end may engage arecess 240 in the second expansion member 55 (e.g., as depicted inFIG. 19 ). A recess may include a shallow opening. The distal end may turn freely in the recess. The recess may assist in centering and/or positioning the distal end of theelongated member 45 such that the distal end is inhibited from misaligning and/or disengaging from the second expansion member. In some embodiments, theimplant 5 may include a secondelongated member 45 b. The secondelongated member 45 b may be positioned in thesecond expansion member 55 andopening 70 such that the second elongated member keeps the second expansion member centered. - In some embodiments, the expansion mechanism may include a first
elongated member 45 a and a secondelongated member 45 b (e.g., as depicted inFIG. 20 ). The firstelongated member 45 a may include a proximally threadedportion 147. Thefirst expansion member 50 may include a threadedopening 180 which the threaded portion of the first elongated member engages, during use. The secondelongated member 45 b may be positionable, during use, in anopening 210 in thesecond expansion member 55. Adistal end 245 of the firstelongated member 45 a may engage, during use, aproximal end 250 of the secondelongated member 45 b. In some embodiments, a distal end of the first elongated member may engage, during use, a proximal end of the second elongated member such that the distal end of the first elongated member is positioned in the opening in the second expansion member. The distal end of the first elongated member may turn freely in the opening in the second expansion member. In some embodiments, the second elongated member may function to keep thesecond expansion member 55 central in the body of the implant. In some embodiments, the second elongated member may be essentially non-rotating relative to the first elongated member. - The result is that the separation between the expansion members is thus equal to just one pitch of the thread per rotation, or ½ pitch of movement relative to the endplate (upper & lower body) each. As such for a given torque one may provide approximately twice the lifting force as compared to dual expansion members moving in the same direction at 1 pitch per rotation. Embodiments discussed herein would have twice the separation force relative to a turnbuckle thread configured with opposing expansion members (or even with expansion members moving in the same direction) because they separate/collapse at a rate of 2 pitches per rotation and thus have twice the motion relative to the endplates.
- In some embodiments, a size of the expansion member (e.g., screw) may be reduced to get the same force at a lower torque because passive rotation within one of the expansion members is more efficient. One may reduce the angle of the ramp or have a single ramp, but you would need considerably more travel to achieve the same height and would run into length limitations. Many embodiments described herein increase rotations not travel.
- Forming the expansion mechanism from two elongated members as opposed to a single elongated member has several advantages. For example when retracting
upper body 35 andlower body 40 from an engaged position to an unengaged position, torque applied to the expansion mechanism during retraction may lead to failure of the expansion mechanism when the expansion mechanism includes a single elongated member. When the expansion mechanism includes two elongated members, failure of the expansion mechanism when counter (retracting) torque is applied is inhibited. - In some embodiments, one or more of the expansion members may include a locking
member 255. The locking member may be positionable in thesecond expansion member 55 such that the second elongated member is inhibited, during use, from removal from the opening in the second expansion member. The locking member may include a pin. The pin may be positioned in an opening in the second expansion member. In some embodiments, the locking member may engage arecess 260 in the second elongated member. The recess may circumscribe the circumference of the second elongated member such that the second elongated member does not have to be oriented in a particular direction relative to the second elongated member. In some embodiments, the locking member may be used in combination with the single elongated member (e.g.,snap ring 215 as depicted inFIG. 2 ). - In some embodiments,
first expansion member 50 includes a generally wedge-shapedbody 155 having asuperior camming surface 160, aninferior cam surface 165, a pair ofsuperior fingers 170 and a pair of inferior fingers 175 (e.g., as depicted inFIG. 16 ). Significantly,superior camming surface 160 offirst expansion member 50 extends parallel tocamming surface 100 ofupper body 35, andinferior camming surface 165 offirst expansion member 50 extends parallel tocamming surface 125 oflower body 40. In lordotic embodiments these surfaces may only be parallel in the open position. They are not parallel when closed.First expansion member 50 may include a threadedbore 180 extending there through. Threaded bore 180 is sized to be threadingly engaged byscrew threads 147 onelongated shaft 135. - In some embodiments,
second expansion member 55 includes a generally wedge-shapedbody 185 having asuperior camming surface 190, aninferior camming surface 195, a pair ofsuperior fingers 200 and a pair of inferior fingers 205 (e.g., as depicted inFIGS. 16-17 ). Significantly,superior camming surface 190 ofsecond expansion member 55 extends parallel tocamming surface 105 ofupper body 35, andinferior camming surface 195 ofsecond expansion member 55 extends parallel tocamming surface 130 oflower body 40. In lordotic embodiments these surfaces may only be parallel in the open position. They are not parallel when closed.Second expansion member 55 may include asmooth bore 210 extending there through.Smooth bore 210 may be sized to receive the portion ofexpansion mechanism 45 distal toannular shoulder 140. - Camming surfaces of the upper/lower bodies and the expansion members may be substantially flat as depicted in some of the attached FIGS. In some embodiments, at least some of the camming surfaces may be curved. Complementary camming surfaces may be complementarily shaped. Complementary camming surfaces may not be complementarily shaped.
- In some embodiments,
intervertebral implant 5 may be assembled so thatexpansion mechanism 45 extends throughproximal opening 75 in cage 30 (without engagingproximal opening 75 in cage 30), andfirst expansion member 50 andsecond expansion member 55 are disposed onshaft 135 ofexpansion mechanism 45 within thehollow interior 65 ofcage 30. More particularly,first expansion member 50 may be mounted onelongated shaft 135 ofexpansion mechanism 45 so thatscrew threads 147 are threadingly received in threadedbore 180 offirst expansion member 50, andsecond expansion member 55 is mounted onelongated shaft 135 ofexpansion mechanism 45 so thatsecond expansion member 55 is captured onelongated shaft 135 betweenannular shoulder 140 and asnap ring 215 secured ingroove 145. At the same time,upper body 35 andlower body 40 may extend intohollow interior 65 ofexterior body 30 so that (i)camming surface 100 ofupper body 35 rides oncamming surface 160 offirst expansion member 50, (ii)camming surface 105 ofupper body 35 rides oncamming surface 190 ofsecond expansion member 55, (iii)camming surface 125 oflower body 40 rides oncamming surface 165 offirst expansion member 50, and (iv)camming surface 130 oflower body 40 rides oncamming surface 195 ofsecond expansion member 55. - It will be appreciated that, as a result of the foregoing construction, the application of torque to
expansion mechanism 45 in one direction (e.g., in anoncircular bore 150 in expansion mechanism 45) causesfirst expansion member 50 andsecond expansion member 55 to separate, whereby to moveupper body 35 andlower body 40 apart and hence increase the height ofintervertebral implant 5. It will be appreciated that, as a result of the foregoing construction, the application of torque toexpansion mechanism 45 in the opposite direction causesfirst expansion member 50 andsecond expansion member 55 to draw together, whereby to moveupper body 35 andlower body 40 together and hence decrease the height ofintervertebral implant 5. - In some embodiments, the
intervertebral implant 5 may include a curved cross-section. Straight designs are more commonly associated with PLIF (direct posterior placement in pairs), or lateral approaches (one longer device placed from the side of the spine).FIG. 21 is a schematic cross-sectional view of a curved expandable fusion device in an unexpanded state with a curved cross-section.FIG. 22 is a schematic cross-sectional view of a curved expandable fusion device in an expanded state with a curved cross-section. In some embodiments, portions of the implant may be curved or angled in order to accommodate the curved cross-section of the perimeter. In some embodiments, expansion members and the expansion mechanism may not require adjustments to assimilate into an implant with a curved perimeter. Thedistal end 235 of theexpansion mechanism 45 a may engage arecess 240 in thesecond expansion member 55 as discussed herein and in the case of a curved implant the recess may adjusted to compensate for the varying angle of engagement of the distal end with the recess during expansion. In some embodiments, the distal end of the expansion mechanism may be curved in order to accommodate a curved perimeter. - The reason TLIF cages are typically curved is that the surgical technique would be to place them from a posterior-lateral approach, as much as 45 degrees off the midline, where they are tamped and rotated to the front of the vertebral body. A curved implant may facilitate insertion of the implant between adjacent vertebrae. An implant with a curved perimeter may better mimic and accommodate the existing perimeter of the average vertebra.
FIG. 23 depicts a schematic view of a curvedexpandable fusion device 5 as the device is being inserted between two adjacent vertebrae. In some embodiments, the implant inserter may be curved. The expansion mechanism may have a flexible shaft to allow rotation within the curve. The relative advantages of an expandable feature may in fact be greater because it would significantly reduce the impaction required to maneuver the device into final position at the front of the spine. - In some embodiments, an implant system may include an
implant insertion device 300.FIG. 18 shows ahandle 215, aholder 220 and an engagingmember 225 which may be used to manipulate and deployintervertebral implant 5. More particularly, handle 215 includes twoextensions 230 for positioning in seats 80 (e.g., as depicted inFIGS. 3-6 ) ofintervertebral implant 5.Holder 220 may be positionable inhandle 215 and threadingly engages the distal end ofexpansion mechanism 45, whereby to releasably secureintervertebral implant 5 to handle 215. Engagingmember 225 may be positionable inholder 220 and intobore 150 inexpansion mechanism 45, whereby to permit the user to turnexpansion mechanism 45 and hence adjust the height of theintervertebral implant 5. Engagingmember 225 may include engaginghead 226 which engages bore 150.Engaging head 226 may include a complementary shape to bore 150 such that as the head turns theexpansion member 45 turns. - In some embodiments, an implant system may include an
implant insertion device 300.FIGS. 24-26 depict a schematic view showinginsertion instruments 300 for use with an expandable fusion device.FIGS. 24-26 depict ahandle 215, aholder 220 and an engagingmember 225 which may be used to manipulate and deployintervertebral implant 5. More particularly, handle 215 includes twoextensions 230 for positioning in seats 80 (e.g., as depicted inFIGS. 24-25 ) ofintervertebral implant 5. Engagingmember 225 may be positionable inholder 220 and intobore 150 inexpansion mechanism 45, whereby to permit the user to turnexpansion mechanism 45 and hence adjust the height of theintervertebral implant 5. Engagingmember 225 may include engaginghead 226 which engages bore 150.Engaging head 226 may include a complementary shape to bore 150 such that as the head turns theexpansion member 45 turns. In some embodiments, theinsertion instrument 300 may include agrip 280 coupled to engagingmember 225. In some embodiments, engagingmember 225 may include a threadedproximal portion 285. The threadedportion 285 may function to assist in controlling longitudinal movement of the engaging member and therefore expansion of the implant. - In some embodiments, an insertion device may be disposable.
FIGS. 27-28 depict a schematic view of a disposable expandable fusionimplant insertion device 300. A disposable insertion device may be packaged with an implant. The insertion device may allow bone graft to be packed after insertion. The “disposable” option may allow the holder to act as an internal funnel which would make cleaning difficult, but a “durable version” remains an option. In some embodiments, engagingmember 225 may be used to pack biological material into the implant throughholder 220. In some embodiments, a separate packing instrument (not depicted) may be used to insert biological material. -
FIGS. 32-36 depict a schematic view showinginsertion instruments 300 for use with an expandable fusion device.FIGS. 32-36 depict ahandle 215, aholder 220 and an engagingmember 225 which may be used to manipulate and deployintervertebral implant 5. More particularly, handle 215 includes twoextensions 230 for positioning in seats 80 (e.g., as depicted inFIGS. 24-25 ) ofintervertebral implant 5. In some embodiments, the extensions may be spring loaded (e.g., using springs, forming at least a portion of the extensions from an at least slightly flexible material, etc.) such that they are biased to be positioned such that they apply pressure to the seats of the implant during use. In some embodiments, a mechanism may be employed to engage/release the extensions from the implant. - The insertion instrument may include at least two
holders 220 which couple to opposing sides (e.g., the inferior and superior surfaces of the implant) of the implant during use. In some embodiments, the holders may be spring loaded (e.g., using springs, forming at least a portion of the holders from an at least slightly flexible material, etc.) such that they are biased to be positioned such that they apply pressure to the surfaces of the implant during use. In some embodiments, a mechanism may be employed to engage/release the holders from the implant. The holders may include a curved edge or lip which curve towards one another. The curved edge may engage an appropriately shaped portion of the proximal end of the implant. - Engaging
member 225 may be positionable inhandle 215 and intobore 150 inexpansion mechanism 45, whereby to permit the user to turnexpansion mechanism 45 and hence adjust the height of theintervertebral implant 5. Engagingmember 225 may include engaginghead 226 which engages bore 150.Engaging head 226 may include a complementary shape to bore 150 such that as the head turns theexpansion member 45 turns. In some embodiments, theinsertion instrument 300 may include agrip 280 coupled to engagingmember 225. - In this patent, certain U.S. patents, U.S. patent applications, and other materials (e.g., articles) have been incorporated by reference. The text of such U.S. patents, U.S. patent applications, and other materials is, however, only incorporated by reference to the extent that no conflict exists between such text and the other statements and drawings set forth herein. In the event of such conflict, then any such conflicting text in such incorporated by reference U.S. patents, U.S. patent applications, and other materials is specifically not incorporated by reference in this patent.
- Further modifications and alternative embodiments of various aspects of the invention will be apparent to those skilled in the art in view of this description. Accordingly, this description is to be construed as illustrative only and is for the purpose of teaching those skilled in the art the general manner of carrying out the invention. It is to be understood that the forms of the invention shown and described herein are to be taken as the presently preferred embodiments. Elements and materials may be substituted for those illustrated and described herein, parts and processes may be reversed, and certain features of the invention may be utilized independently, all as would be apparent to one skilled in the art after having the benefit of this description of the invention. Changes may be made in the elements described herein without departing from the spirit and scope of the invention as described in the following claims.
Claims (5)
1.-17. (canceled)
18. A method for maintaining the spacing between two adjacent vertebral bodies, comprising:
removing at least a portion of a disc between two vertebrae of the human spine to create a disc space between the two vertebrae;
positioning an unexpanded intervertebral implant in the disc space between the two vertebrae, wherein the intervertebral implant comprises:
an upper body comprising an inferior surface and a superior surface;
a lower body comprising a superior surface and an inferior surface;
a first expansion member comprising at least a first angled portion positionable, during use, between the inferior surface of the upper body and the superior surface of the lower body, wherein at least the first angled portion is oriented towards a first end of the intervertebral implant;
a second expansion member comprising at least a second angled portion positionable, during use, between the inferior surface of the upper body and the superior surface of the lower body, wherein at least the second angled portion is oriented towards a second end of the intervertebral implant, wherein at least the second angled portion is oriented in an opposing direction relative to at least the first angled portion; and
an expansion mechanism;
moving the first and second expansion members in opposing directions using the expansion member; and
increasing a separation distance between the upper body and the lower body.
19. The method of claim 18 , further comprising engaging a first vertebra of the human spine using the superior surface of the upper body.
20. The method of claim 18 , further comprising engaging a second vertebra of the human spine using the inferior surface of the lower body.
21. The method of claim 18 , further comprising:
increasing a size of an opening between the first and second angled portions as the first and second angled portions are conveyed in opposing directions; and
positioning graft material in the opening between first and second angled portions.
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Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10052215B2 (en) * | 2016-06-29 | 2018-08-21 | Globus Medical, Inc. | Expandable fusion device and method of installation thereof |
US10322014B2 (en) | 2013-09-09 | 2019-06-18 | Integrity Implants Inc. | Expandable trial with telescopic stabilizers |
US10383743B2 (en) | 2016-09-21 | 2019-08-20 | Integrity Implants Inc. | Laterovertically-expanding fusion cage systems |
US10507116B2 (en) | 2017-01-10 | 2019-12-17 | Integrity Implants Inc. | Expandable intervertebral fusion device |
US10709578B2 (en) | 2017-08-25 | 2020-07-14 | Integrity Implants Inc. | Surgical biologics delivery system and related methods |
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US10758368B2 (en) | 2015-01-20 | 2020-09-01 | Integrity Implants Inc. | Stabilized, 4 beam intervertebral scaffolding system |
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US11013610B2 (en) * | 2017-10-18 | 2021-05-25 | Spine Wave, Inc. | Expandable anterior lumbar interbody fusion device |
US11013612B2 (en) | 2012-08-31 | 2021-05-25 | Institute for Musculoskeletal Science and Education, Ltd. | Fixation devices for anterior lumbar or cervical interbody fusion |
US11224522B2 (en) | 2017-07-24 | 2022-01-18 | Integrity Implants Inc. | Surgical implant and related methods |
US11246716B2 (en) | 2016-10-18 | 2022-02-15 | Institute for Musculoskeletal Science and Education, Ltd. | Implant with deployable blades |
USD946151S1 (en) | 2020-11-06 | 2022-03-15 | Mirus Llc | Medical device |
US11285018B2 (en) | 2018-03-01 | 2022-03-29 | Integrity Implants Inc. | Expandable fusion device with independent expansion systems |
US11413157B2 (en) | 2016-10-25 | 2022-08-16 | Institute for Musculoskeletal Science and Education, Ltd. | Spinal fusion implant |
US11872143B2 (en) | 2016-10-25 | 2024-01-16 | Camber Spine Technologies, LLC | Spinal fusion implant |
US11918489B2 (en) | 2021-04-02 | 2024-03-05 | Nuvasive Inc. | Expansion driver |
US11951016B2 (en) | 2021-05-11 | 2024-04-09 | Integrity Implants Inc. | Spinal fusion device with staged expansion |
Families Citing this family (145)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7041309B2 (en) | 2002-06-13 | 2006-05-09 | Neuropro Technologies, Inc. | Spinal fusion using an HMG-CoA reductase inhibitor |
US8597360B2 (en) | 2004-11-03 | 2013-12-03 | Neuropro Technologies, Inc. | Bone fusion device |
US9801733B2 (en) * | 2005-03-31 | 2017-10-31 | Life Spine, Inc. | Expandable spinal interbody and intravertebral body devices |
US9526525B2 (en) | 2006-08-22 | 2016-12-27 | Neuropro Technologies, Inc. | Percutaneous system for dynamic spinal stabilization |
US8105382B2 (en) | 2006-12-07 | 2012-01-31 | Interventional Spine, Inc. | Intervertebral implant |
EP2124778B1 (en) | 2007-02-21 | 2019-09-25 | Benvenue Medical, Inc. | Devices for treating the spine |
US8900307B2 (en) | 2007-06-26 | 2014-12-02 | DePuy Synthes Products, LLC | Highly lordosed fusion cage |
EP2237748B1 (en) | 2008-01-17 | 2012-09-05 | Synthes GmbH | An expandable intervertebral implant |
US8088163B1 (en) | 2008-02-06 | 2012-01-03 | Kleiner Jeffrey B | Tools and methods for spinal fusion |
CA2720580A1 (en) | 2008-04-05 | 2009-10-08 | Synthes Usa, Llc | Expandable intervertebral implant |
US8366748B2 (en) | 2008-12-05 | 2013-02-05 | Kleiner Jeffrey | Apparatus and method of spinal implant and fusion |
CN102369332B (en) | 2008-12-31 | 2014-07-02 | 奥马尔·F·希门尼斯 | Flexible joint arrangement incorporating flexure members |
US9247943B1 (en) | 2009-02-06 | 2016-02-02 | Kleiner Intellectual Property, Llc | Devices and methods for preparing an intervertebral workspace |
US8628577B1 (en) | 2009-03-19 | 2014-01-14 | Ex Technology, Llc | Stable device for intervertebral distraction and fusion |
US9526620B2 (en) | 2009-03-30 | 2016-12-27 | DePuy Synthes Products, Inc. | Zero profile spinal fusion cage |
US9642722B2 (en) | 2009-07-02 | 2017-05-09 | Atlas Spine, Inc. | Intervertebral expandable spacer |
EP2457001B1 (en) | 2009-07-22 | 2017-11-01 | Spinex Tec, LLC | Coaxial screw gear sleeve mechanism |
US20170238984A1 (en) | 2009-09-18 | 2017-08-24 | Spinal Surgical Strategies, Llc | Bone graft delivery device with positioning handle |
US8906028B2 (en) | 2009-09-18 | 2014-12-09 | Spinal Surgical Strategies, Llc | Bone graft delivery device and method of using the same |
US9629729B2 (en) | 2009-09-18 | 2017-04-25 | Spinal Surgical Strategies, Llc | Biological delivery system with adaptable fusion cage interface |
US10973656B2 (en) | 2009-09-18 | 2021-04-13 | Spinal Surgical Strategies, Inc. | Bone graft delivery system and method for using same |
US10245159B1 (en) | 2009-09-18 | 2019-04-02 | Spinal Surgical Strategies, Llc | Bone graft delivery system and method for using same |
CN102892387B (en) | 2010-03-16 | 2016-03-16 | 品尼高脊柱集团有限责任公司 | Intervertebral implant and graft induction system and method |
US9907560B2 (en) | 2010-06-24 | 2018-03-06 | DePuy Synthes Products, Inc. | Flexible vertebral body shavers |
US8979860B2 (en) | 2010-06-24 | 2015-03-17 | DePuy Synthes Products. LLC | Enhanced cage insertion device |
US10779957B2 (en) * | 2010-09-03 | 2020-09-22 | Globus Medical, Inc. | Expandable fusion device and method of installation thereof |
US9402732B2 (en) | 2010-10-11 | 2016-08-02 | DePuy Synthes Products, Inc. | Expandable interspinous process spacer implant |
US8518087B2 (en) | 2011-03-10 | 2013-08-27 | Interventional Spine, Inc. | Method and apparatus for minimally invasive insertion of intervertebral implants |
US8394129B2 (en) | 2011-03-10 | 2013-03-12 | Interventional Spine, Inc. | Method and apparatus for minimally invasive insertion of intervertebral implants |
US9265620B2 (en) | 2011-03-18 | 2016-02-23 | Raed M. Ali, M.D., Inc. | Devices and methods for transpedicular stabilization of the spine |
WO2013023096A1 (en) | 2011-08-09 | 2013-02-14 | Neuropro Technologies, Inc. | Bone fusion device, system and method |
US10420654B2 (en) | 2011-08-09 | 2019-09-24 | Neuropro Technologies, Inc. | Bone fusion device, system and method |
US9358123B2 (en) * | 2011-08-09 | 2016-06-07 | Neuropro Spinal Jaxx, Inc. | Bone fusion device, apparatus and method |
US9380932B1 (en) | 2011-11-02 | 2016-07-05 | Pinnacle Spine Group, Llc | Retractor devices for minimally invasive access to the spine |
US10159583B2 (en) | 2012-04-13 | 2018-12-25 | Neuropro Technologies, Inc. | Bone fusion device |
US9532883B2 (en) | 2012-04-13 | 2017-01-03 | Neuropro Technologies, Inc. | Bone fusion device |
US8940052B2 (en) | 2012-07-26 | 2015-01-27 | DePuy Synthes Products, LLC | Expandable implant |
US20140067069A1 (en) | 2012-08-30 | 2014-03-06 | Interventional Spine, Inc. | Artificial disc |
US9204972B2 (en) * | 2013-03-01 | 2015-12-08 | Globus Medical, Inc. | Articulating expandable intervertebral implant |
US10004607B2 (en) * | 2013-03-01 | 2018-06-26 | Globus Medical, Inc. | Articulating expandable intervertebral implant |
US9198772B2 (en) * | 2013-03-01 | 2015-12-01 | Globus Medical, Inc. | Articulating expandable intervertebral implant |
US9522070B2 (en) * | 2013-03-07 | 2016-12-20 | Interventional Spine, Inc. | Intervertebral implant |
US9277928B2 (en) | 2013-03-11 | 2016-03-08 | Interventional Spine, Inc. | Method and apparatus for minimally invasive insertion of intervertebral implants |
US10383741B2 (en) | 2013-03-13 | 2019-08-20 | Life Spine, Inc. | Expandable spinal interbody assembly |
US10154911B2 (en) * | 2013-03-13 | 2018-12-18 | Life Spine, Inc. | Expandable implant assembly |
US11304818B2 (en) | 2013-03-13 | 2022-04-19 | Life Spine, Inc. | Expandable spinal interbody assembly |
US10426632B2 (en) | 2013-03-13 | 2019-10-01 | Life Spine, Inc. | Expandable spinal interbody assembly |
US9993353B2 (en) | 2013-03-14 | 2018-06-12 | DePuy Synthes Products, Inc. | Method and apparatus for minimally invasive insertion of intervertebral implants |
US9480574B2 (en) | 2013-03-14 | 2016-11-01 | Benvenue Medical, Inc. | Spinal fusion implants and devices and methods for deploying such implants |
US10070970B2 (en) | 2013-03-14 | 2018-09-11 | Pinnacle Spine Group, Llc | Interbody implants and graft delivery systems |
US10687962B2 (en) | 2013-03-14 | 2020-06-23 | Raed M. Ali, M.D., Inc. | Interbody fusion devices, systems and methods |
JP6836899B2 (en) * | 2013-03-14 | 2021-03-03 | ラエド エム.アリ,エム.ディー.,インク. | Lateral interbody fusion devices, systems, and methods |
US11311312B2 (en) | 2013-03-15 | 2022-04-26 | Medtronic, Inc. | Subcutaneous delivery tool |
AU2014236698B2 (en) | 2013-03-15 | 2018-09-13 | Neuropro Technologies, Inc. | Bodiless bone fusion device, apparatus and method |
WO2014145995A2 (en) | 2013-03-15 | 2014-09-18 | Spectrum Spine Ip Holdings, Llc | Expandable inter-body fusion devices and methods |
US9788971B1 (en) * | 2013-05-22 | 2017-10-17 | Nuvasive, Inc. | Expandable fusion implant and related methods |
US9801734B1 (en) * | 2013-08-09 | 2017-10-31 | Nuvasive, Inc. | Lordotic expandable interbody implant |
US9364341B2 (en) * | 2014-01-09 | 2016-06-14 | Warsaw Orthopedic, Inc. | Spinal implant system and method |
US9402739B2 (en) * | 2014-02-07 | 2016-08-02 | Globus Medical, Inc. | Variable lordosis spacer and related methods of use |
US9486328B2 (en) | 2014-04-01 | 2016-11-08 | Ex Technology, Llc | Expandable intervertebral cage |
US9498347B2 (en) * | 2014-06-25 | 2016-11-22 | Spine Wave, Inc. | Expandable interbody fusion device with nested correction surface |
US10314605B2 (en) | 2014-07-08 | 2019-06-11 | Benvenue Medical, Inc. | Apparatus and methods for disrupting intervertebral disc tissue |
WO2016049784A1 (en) * | 2014-09-29 | 2016-04-07 | Startech Engineering Ag | Expandable spinal implant |
FR3026294A1 (en) * | 2014-09-30 | 2016-04-01 | Yellowsteps | INTERSOMATIC CAGE WITH ADJUSTABLE COVER AND METHOD OF MANUFACTURING THE SAME |
US10575964B2 (en) * | 2014-10-28 | 2020-03-03 | Spectrum Spine Ip Holdings, Llc | Expandable, adjustable inter-body fusion devices and methods |
WO2016069796A1 (en) * | 2014-10-28 | 2016-05-06 | Spectrum Spine Ip Holdings, Llc | Expandable, adjustable inter-body fusion devices and methods |
US10363142B2 (en) | 2014-12-11 | 2019-07-30 | K2M, Inc. | Expandable spinal implants |
US10022243B2 (en) | 2015-02-06 | 2018-07-17 | Benvenue Medical, Inc. | Graft material injector system and method |
US11426290B2 (en) * | 2015-03-06 | 2022-08-30 | DePuy Synthes Products, Inc. | Expandable intervertebral implant, system, kit and method |
CH711040A1 (en) * | 2015-05-05 | 2016-11-15 | Rs-Technik Cad-Cam Gmbh | Intervertebral implant. |
AU2016260301B2 (en) | 2015-05-12 | 2020-06-25 | Nuvasive, Inc. | Expandable lordosis intervertebral implants |
US9713536B2 (en) * | 2015-08-12 | 2017-07-25 | Warsaw Orthopedic, Inc. | Expandable spinal implant and method of implanting same |
US10137009B2 (en) * | 2015-09-02 | 2018-11-27 | Globus Medical, Inc. | Expandable intervertebral fusion devices and methods of installation thereof |
EP3349686B1 (en) * | 2015-09-18 | 2020-08-12 | The Board of Trustees of the University of Illinois | Adjustable, implantable spinal disc device for deformity correction in intervertebral fusion procedures |
USD797290S1 (en) | 2015-10-19 | 2017-09-12 | Spinal Surgical Strategies, Llc | Bone graft delivery tool |
CN105342729B (en) * | 2015-12-09 | 2017-05-24 | 北京市富乐科技开发有限公司 | Arc-shaped distraction fusion apparatus |
WO2017117513A1 (en) * | 2015-12-30 | 2017-07-06 | Nuvasive, Inc. | Lordotic expandable fusion implant |
US10076423B2 (en) | 2016-01-04 | 2018-09-18 | Warsaw Orthopedic, Inc. | Pivoting wedge expanding spinal implant and method of implanting same |
US11596523B2 (en) | 2016-06-28 | 2023-03-07 | Eit Emerging Implant Technologies Gmbh | Expandable and angularly adjustable articulating intervertebral cages |
EP3474783B1 (en) | 2016-06-28 | 2023-05-03 | Eit Emerging Implant Technologies GmbH | Expandable, angularly adjustable intervertebral cages |
US9974662B2 (en) * | 2016-06-29 | 2018-05-22 | Globus Medical, Inc. | Expandable fusion device and method of installation thereof |
US10537436B2 (en) | 2016-11-01 | 2020-01-21 | DePuy Synthes Products, Inc. | Curved expandable cage |
CN108143522A (en) * | 2016-12-02 | 2018-06-12 | 上海锐植医疗器械有限公司 | A kind of height-adjustable fusion device |
US20180161175A1 (en) * | 2016-12-14 | 2018-06-14 | DePuy Synthes Products, Inc. | Intervertebral implant inserter and related methods |
US10888433B2 (en) | 2016-12-14 | 2021-01-12 | DePuy Synthes Products, Inc. | Intervertebral implant inserter and related methods |
EP3345575B1 (en) * | 2017-01-06 | 2023-08-16 | Ke Ling Biotech Limited | Expandable spinal interbody cage |
TWM558049U (en) * | 2017-01-06 | 2018-04-11 | 克菱生技有限公司 | Expandable spinal interbody cage |
US10729560B2 (en) | 2017-01-18 | 2020-08-04 | Neuropro Technologies, Inc. | Bone fusion system, device and method including an insertion instrument |
US10111760B2 (en) | 2017-01-18 | 2018-10-30 | Neuropro Technologies, Inc. | Bone fusion system, device and method including a measuring mechanism |
US10213321B2 (en) | 2017-01-18 | 2019-02-26 | Neuropro Technologies, Inc. | Bone fusion system, device and method including delivery apparatus |
WO2018136304A1 (en) * | 2017-01-18 | 2018-07-26 | Neuropro Technologies, Inc. | Bone fusion device, system and method |
US10973657B2 (en) | 2017-01-18 | 2021-04-13 | Neuropro Technologies, Inc. | Bone fusion surgical system and method |
EP3357459A1 (en) | 2017-02-03 | 2018-08-08 | Spinal Surgical Strategies, LLC | Bone graft delivery device with positioning handle |
US10758286B2 (en) | 2017-03-22 | 2020-09-01 | Benvenue Medical, Inc. | Minimal impact access system to disc space |
US10398563B2 (en) | 2017-05-08 | 2019-09-03 | Medos International Sarl | Expandable cage |
US11344424B2 (en) | 2017-06-14 | 2022-05-31 | Medos International Sarl | Expandable intervertebral implant and related methods |
CN107157629A (en) * | 2017-06-15 | 2017-09-15 | 北京安德思考普商贸有限公司 | New vertebrae mixer |
US10940016B2 (en) | 2017-07-05 | 2021-03-09 | Medos International Sarl | Expandable intervertebral fusion cage |
US11033403B2 (en) | 2017-07-10 | 2021-06-15 | Life Spine, Inc. | Expandable implant assembly |
US11896494B2 (en) | 2017-07-10 | 2024-02-13 | Life Spine, Inc. | Expandable implant assembly |
US10441430B2 (en) * | 2017-07-24 | 2019-10-15 | K2M, Inc. | Expandable spinal implants |
JP7337087B2 (en) | 2017-12-18 | 2023-09-01 | ニューヴェイジヴ,インコーポレイテッド | expandable implant device |
US11583327B2 (en) | 2018-01-29 | 2023-02-21 | Spinal Elements, Inc. | Minimally invasive interbody fusion |
US10278830B1 (en) | 2018-02-07 | 2019-05-07 | Zavation, Llc | Expandable orthopedic implant |
AU2019226102A1 (en) | 2018-02-22 | 2020-08-13 | Warsaw Orthopedic, Inc. | Expandable spinal implant system and method of using same |
EP3755272A4 (en) | 2018-02-22 | 2021-11-17 | Warsaw Orthopedic, Inc. | Expandable spinal implant system and method of using same |
US11806250B2 (en) * | 2018-02-22 | 2023-11-07 | Warsaw Orthopedic, Inc. | Expandable spinal implant system and method of using same |
US10869769B2 (en) * | 2018-03-06 | 2020-12-22 | Eit Emerging Implant Technologies Gmbh | Intervertebral cages with integrated expansion and angular adjustment mechanism |
WO2019178575A1 (en) | 2018-03-16 | 2019-09-19 | Benvenue Medical, Inc. | Articulated instrumentation and methods of using the same |
FR3087334B1 (en) * | 2018-10-18 | 2021-11-05 | Hassan Razian | INTEROSSEUSE CAGE |
US11446156B2 (en) | 2018-10-25 | 2022-09-20 | Medos International Sarl | Expandable intervertebral implant, inserter instrument, and related methods |
CN109758272B (en) * | 2019-02-26 | 2020-01-17 | 珠海维尔康生物科技有限公司 | Distracting fusion cage with adjustable middle bone grafting height |
US11234835B2 (en) | 2019-03-05 | 2022-02-01 | Octagon Spine Llc | Transversely expandable minimally invasive intervertebral cage |
US11497622B2 (en) | 2019-03-05 | 2022-11-15 | Ex Technology, Llc | Transversely expandable minimally invasive intervertebral cage and insertion and extraction device |
USD955579S1 (en) | 2019-04-26 | 2022-06-21 | Warsaw Orthopedic, Inc. | Surgical implant |
USD948048S1 (en) | 2019-04-26 | 2022-04-05 | Warsaw Orthopedic, Inc. | Surgical implant |
WO2020251943A1 (en) | 2019-06-10 | 2020-12-17 | Life Spine, Inc. | Expandable implant assembly with compression features |
US11678906B2 (en) | 2019-09-09 | 2023-06-20 | Amplify Surgical, Inc. | Multi-portal surgical systems, cannulas, and related technologies |
US11464648B2 (en) | 2019-09-09 | 2022-10-11 | Amplify Surgical, Inc. | Multi-portal surgical systems |
US11547575B2 (en) | 2019-09-27 | 2023-01-10 | Degen Medical, Inc. | Expandable intervertebral spacers |
US11191650B2 (en) * | 2020-02-03 | 2021-12-07 | Globus Medical Inc. | Expandable fusions devices, instruments, and methods thereof |
US11564809B2 (en) | 2020-03-05 | 2023-01-31 | Alphatec Spine, Inc. | Expandable interbodies and related methods |
US11426286B2 (en) | 2020-03-06 | 2022-08-30 | Eit Emerging Implant Technologies Gmbh | Expandable intervertebral implant |
US11857432B2 (en) | 2020-04-13 | 2024-01-02 | Life Spine, Inc. | Expandable implant assembly |
US11602439B2 (en) | 2020-04-16 | 2023-03-14 | Life Spine, Inc. | Expandable implant assembly |
US11298240B2 (en) * | 2020-06-16 | 2022-04-12 | Globus Medical, Inc. | Expanding intervertebral implants |
US11602440B2 (en) | 2020-06-25 | 2023-03-14 | Life Spine, Inc. | Expandable implant assembly |
US11554020B2 (en) | 2020-09-08 | 2023-01-17 | Life Spine, Inc. | Expandable implant with pivoting control assembly |
US11638653B2 (en) | 2020-11-05 | 2023-05-02 | Warsaw Orthopedic, Inc. | Surgery instruments with a movable handle |
US20220133497A1 (en) * | 2020-11-05 | 2022-05-05 | Warsaw Orthopedic, Inc. | Dual wedge expandable implant with eyelets, system, and method of use |
US11833059B2 (en) | 2020-11-05 | 2023-12-05 | Warsaw Orthopedic, Inc. | Expandable inter-body device, expandable plate system, and associated methods |
US11291554B1 (en) | 2021-05-03 | 2022-04-05 | Medtronic, Inc. | Unibody dual expanding interbody implant |
US11376134B1 (en) | 2020-11-05 | 2022-07-05 | Warsaw Orthopedic, Inc. | Dual expanding spinal implant, system, and method of use |
US11285014B1 (en) | 2020-11-05 | 2022-03-29 | Warsaw Orthopedic, Inc. | Expandable inter-body device, system, and method |
US11617658B2 (en) | 2020-11-05 | 2023-04-04 | Warsaw Orthopedic, Inc. | Expandable inter-body device, system and method |
US11517443B2 (en) * | 2020-11-05 | 2022-12-06 | Warsaw Orthopedic, Inc. | Dual wedge expandable implant, system and method of use |
US11395743B1 (en) | 2021-05-04 | 2022-07-26 | Warsaw Orthopedic, Inc. | Externally driven expandable interbody and related methods |
US11291559B1 (en) * | 2021-03-05 | 2022-04-05 | CTL Amedica Corporation | Expandable interbody fusion device and method of manufacturing the same |
US11850160B2 (en) | 2021-03-26 | 2023-12-26 | Medos International Sarl | Expandable lordotic intervertebral fusion cage |
US11752009B2 (en) | 2021-04-06 | 2023-09-12 | Medos International Sarl | Expandable intervertebral fusion cage |
US11173044B1 (en) | 2021-04-20 | 2021-11-16 | Zavation Medical Products, Llc | Expanding orthopedic implant |
US11612499B2 (en) | 2021-06-24 | 2023-03-28 | Warsaw Orthopedic, Inc. | Expandable interbody implant |
US11730608B2 (en) | 2021-07-13 | 2023-08-22 | Warsaw Orthopedic, Inc. | Monoblock expandable interbody implant |
US11389303B1 (en) | 2021-10-07 | 2022-07-19 | Zavation Medical Products, Llc | Externally threaded expandable orthopedic implant |
US11850163B2 (en) | 2022-02-01 | 2023-12-26 | Warsaw Orthopedic, Inc. | Interbody implant with adjusting shims |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7217291B2 (en) * | 2003-12-08 | 2007-05-15 | St. Francis Medical Technologies, Inc. | System and method for replacing degenerated spinal disks |
US20120059470A1 (en) * | 2010-09-03 | 2012-03-08 | Mark Weiman | Expandable Fusion Device and Method of Installation Thereof |
WO2013023098A1 (en) * | 2011-08-09 | 2013-02-14 | Neuropro Spinal Jaxx Inc. | Bone fusion device, apparatus and method |
US20130204371A1 (en) * | 2011-08-09 | 2013-08-08 | Gary R. McLuen | Bone fusion device, system and method |
US20140277500A1 (en) * | 2013-03-15 | 2014-09-18 | Neuropro Technologies, INC | Bodiless bone fusion device, apparatus and method |
US9320610B2 (en) * | 2011-08-16 | 2016-04-26 | Stryker European Holdings I, Llc | Expandable implant |
Family Cites Families (481)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE391122B (en) | 1971-01-25 | 1977-02-07 | Cutter Lab | PROTESTS IN THE FORM OF A SPINE BONIC DISC AND PROCEDURES FOR MANUFACTURE THEREOF |
US3848601A (en) | 1972-06-14 | 1974-11-19 | G Ma | Method for interbody fusion of the spine |
CA1146301A (en) | 1980-06-13 | 1983-05-17 | J. David Kuntz | Intervertebral disc prosthesis |
US4309777A (en) | 1980-11-13 | 1982-01-12 | Patil Arun A | Artificial intervertebral disc |
US4696290A (en) | 1983-12-16 | 1987-09-29 | Acromed Corporation | Apparatus for straightening spinal columns |
US4611581A (en) | 1983-12-16 | 1986-09-16 | Acromed Corporation | Apparatus for straightening spinal columns |
GB2173104B (en) | 1984-02-28 | 1987-11-25 | Peter John Webb | Spinal fixation apparatus |
EP0176728B1 (en) | 1984-09-04 | 1989-07-26 | Humboldt-Universität zu Berlin | Intervertebral-disc prosthesis |
FR2575059B1 (en) | 1984-12-21 | 1988-11-10 | Daher Youssef | SHORING DEVICE FOR USE IN A VERTEBRAL PROSTHESIS |
US4743260A (en) | 1985-06-10 | 1988-05-10 | Burton Charles V | Method for a flexible stabilization system for a vertebral column |
US4854311A (en) | 1986-01-09 | 1989-08-08 | Acro Med Corporation | Bone screw |
DE3614101C1 (en) | 1986-04-25 | 1987-10-22 | Juergen Prof Dr Med Harms | Pedicle screw |
GB8620937D0 (en) | 1986-08-29 | 1986-10-08 | Shepperd J A N | Spinal implant |
CA1283501C (en) | 1987-02-12 | 1991-04-30 | Thomas P. Hedman | Artificial spinal disc |
US4863477A (en) | 1987-05-12 | 1989-09-05 | Monson Gary L | Synthetic intervertebral disc prosthesis |
DE3800052A1 (en) | 1987-07-08 | 1989-07-13 | Harms Juergen | POSITIONING SCREW |
US5108438A (en) | 1989-03-02 | 1992-04-28 | Regen Corporation | Prosthetic intervertebral disc |
US4772287A (en) | 1987-08-20 | 1988-09-20 | Cedar Surgical, Inc. | Prosthetic disc and method of implanting |
JPH01136655A (en) | 1987-11-24 | 1989-05-29 | Asahi Optical Co Ltd | Movable type pyramid spacer |
US4911718A (en) | 1988-06-10 | 1990-03-27 | University Of Medicine & Dentistry Of N.J. | Functional and biocompatible intervertebral disc spacer |
EP0703757B1 (en) | 1988-06-13 | 2003-08-27 | Karlin Technology, Inc. | Apparatus for inserting spinal implants |
US5484437A (en) | 1988-06-13 | 1996-01-16 | Michelson; Gary K. | Apparatus and method of inserting spinal implants |
US5015247A (en) | 1988-06-13 | 1991-05-14 | Michelson Gary K | Threaded spinal implant |
US5772661A (en) | 1988-06-13 | 1998-06-30 | Michelson; Gary Karlin | Methods and instrumentation for the surgical correction of human thoracic and lumbar spinal disease from the antero-lateral aspect of the spine |
US7452359B1 (en) | 1988-06-13 | 2008-11-18 | Warsaw Orthopedic, Inc. | Apparatus for inserting spinal implants |
US5609635A (en) | 1988-06-28 | 1997-03-11 | Michelson; Gary K. | Lordotic interbody spinal fusion implants |
CA1333209C (en) | 1988-06-28 | 1994-11-29 | Gary Karlin Michelson | Artificial spinal fusion implants |
DE3823737A1 (en) | 1988-07-13 | 1990-01-18 | Lutz Biedermann | CORRECTION AND HOLDING DEVICE, ESPECIALLY FOR THE SPINE |
AU624627B2 (en) | 1988-08-18 | 1992-06-18 | Johnson & Johnson Orthopaedics, Inc. | Functional and biocompatible intervertebral disc spacer containing elastomeric material of varying hardness |
CA1318469C (en) | 1989-02-15 | 1993-06-01 | Acromed Corporation | Artificial disc |
US4907577A (en) | 1989-04-03 | 1990-03-13 | Wu Shing Sheng | Spinal transpedicle drill jig |
US5895427A (en) | 1989-07-06 | 1999-04-20 | Sulzer Spine-Tech Inc. | Method for spinal fixation |
DE3923996A1 (en) | 1989-07-20 | 1991-01-31 | Lutz Biedermann | RECORDING PART FOR JOINTLY CONNECTING TO A SCREW FOR MAKING A PEDICLE SCREW |
US4932975A (en) | 1989-10-16 | 1990-06-12 | Vanderbilt University | Vertebral prosthesis |
DE3936702C2 (en) | 1989-11-03 | 1994-07-28 | Lutz Biedermann | Pedicle screw and correction and holding device with such a pedicle screw |
US5059194A (en) | 1990-02-12 | 1991-10-22 | Michelson Gary K | Cervical distractor |
FR2659226B1 (en) | 1990-03-07 | 1992-05-29 | Jbs Sa | PROSTHESIS FOR INTERVERTEBRAL DISCS AND ITS IMPLEMENTATION INSTRUMENTS. |
US5360431A (en) | 1990-04-26 | 1994-11-01 | Cross Medical Products | Transpedicular screw system and method of use |
GB9014817D0 (en) | 1990-07-04 | 1990-08-22 | Mehdian Seyed M H | Improvements in or relating to apparatus for use in the treatment of spinal disorders |
FR2666981B1 (en) | 1990-09-21 | 1993-06-25 | Commarmond Jacques | SYNTHETIC LIGAMENT VERTEBRAL. |
US5047055A (en) | 1990-12-21 | 1991-09-10 | Pfizer Hospital Products Group, Inc. | Hydrogel intervertebral disc nucleus |
US5192326A (en) | 1990-12-21 | 1993-03-09 | Pfizer Hospital Products Group, Inc. | Hydrogel bead intervertebral disc nucleus |
US5123926A (en) | 1991-02-22 | 1992-06-23 | Madhavan Pisharodi | Artificial spinal prosthesis |
US5171278A (en) | 1991-02-22 | 1992-12-15 | Madhavan Pisharodi | Middle expandable intervertebral disk implants |
JP3007903B2 (en) | 1991-03-29 | 2000-02-14 | 京セラ株式会社 | Artificial disc |
FR2676911B1 (en) | 1991-05-30 | 1998-03-06 | Psi Ste Civile Particuliere | INTERVERTEBRAL STABILIZATION DEVICE WITH SHOCK ABSORBERS. |
US5306307A (en) | 1991-07-22 | 1994-04-26 | Calcitek, Inc. | Spinal disk implant |
US5320644A (en) | 1991-08-30 | 1994-06-14 | Sulzer Brothers Limited | Intervertebral disk prosthesis |
GB9125798D0 (en) | 1991-12-04 | 1992-02-05 | Customflex Limited | Improvements in or relating to spinal vertebrae implants |
US5425773A (en) | 1992-01-06 | 1995-06-20 | Danek Medical, Inc. | Intervertebral disk arthroplasty device |
US5258031A (en) | 1992-01-06 | 1993-11-02 | Danek Medical | Intervertebral disk arthroplasty |
US5261909A (en) | 1992-02-18 | 1993-11-16 | Danek Medical, Inc. | Variable angle screw for spinal implant system |
DE4208116C2 (en) | 1992-03-13 | 1995-08-03 | Link Waldemar Gmbh Co | Intervertebral disc prosthesis |
DE4208115A1 (en) | 1992-03-13 | 1993-09-16 | Link Waldemar Gmbh Co | DISC ENDOPROTHESIS |
EP0566810B1 (en) | 1992-04-21 | 1996-08-14 | SULZER Medizinaltechnik AG | Artificial spinal disc |
CA2134671A1 (en) | 1992-04-29 | 1993-11-11 | Richard B. Ashman | Positionable spinal fixation device |
US5306309A (en) | 1992-05-04 | 1994-04-26 | Calcitek, Inc. | Spinal disk implant and implantation kit |
FR2692952B1 (en) | 1992-06-25 | 1996-04-05 | Psi | IMPROVED SHOCK ABSORBER WITH MOVEMENT LIMIT. |
US5545165A (en) | 1992-10-09 | 1996-08-13 | Biedermann Motech Gmbh | Anchoring member |
US5246458A (en) | 1992-10-07 | 1993-09-21 | Graham Donald V | Artificial disk |
JPH06178787A (en) | 1992-12-14 | 1994-06-28 | Shima Yumiko | Centrum spacer with joint, intervertebral cavity measuring device and centrum spacer pattern |
US5527314A (en) | 1993-01-04 | 1996-06-18 | Danek Medical, Inc. | Spinal fixation system |
US5676701A (en) | 1993-01-14 | 1997-10-14 | Smith & Nephew, Inc. | Low wear artificial spinal disc |
AU3502893A (en) | 1993-01-19 | 1994-08-15 | Jbs Sa | Spinal osteosynthesis device |
US5336223A (en) | 1993-02-04 | 1994-08-09 | Rogers Charles L | Telescoping spinal fixator |
EP0610837B1 (en) | 1993-02-09 | 2001-09-05 | Acromed Corporation | Spine disc |
FR2701650B1 (en) | 1993-02-17 | 1995-05-24 | Psi | Double shock absorber for intervertebral stabilization. |
DE4307576C1 (en) | 1993-03-10 | 1994-04-21 | Biedermann Motech Gmbh | Bone screw esp. for spinal column correction - has U=shaped holder section for receiving straight or bent rod |
US5415661A (en) | 1993-03-24 | 1995-05-16 | University Of Miami | Implantable spinal assist device |
US5534028A (en) | 1993-04-20 | 1996-07-09 | Howmedica, Inc. | Hydrogel intervertebral disc nucleus with diminished lateral bulging |
EP0621020A1 (en) | 1993-04-21 | 1994-10-26 | SULZER Medizinaltechnik AG | Intervertebral prosthesis and method of implanting such a prosthesis |
FR2707480B1 (en) | 1993-06-28 | 1995-10-20 | Bisserie Michel | Intervertebral disc prosthesis. |
US5423816A (en) | 1993-07-29 | 1995-06-13 | Lin; Chih I. | Intervertebral locking device |
DE4328690B4 (en) | 1993-08-26 | 2006-08-17 | SDGI Holdings, Inc., Wilmington | Intervertebral implant for vertebral body blocking and implantation instrument for positioning the intervertebral implant |
FR2709246B1 (en) | 1993-08-27 | 1995-09-29 | Martin Jean Raymond | Dynamic implanted spinal orthosis. |
FR2709247B1 (en) | 1993-08-27 | 1995-09-29 | Martin Jean Raymond | Device for anchoring spinal instrumentation on a vertebra. |
FR2709949B1 (en) | 1993-09-14 | 1995-10-13 | Commissariat Energie Atomique | Intervertebral disc prosthesis. |
US5397364A (en) | 1993-10-12 | 1995-03-14 | Danek Medical, Inc. | Anterior interbody fusion device |
FR2712481B1 (en) | 1993-11-18 | 1996-01-12 | Graf Henry | Improvements to flexible inter-vertebral stabilizers. |
ATE262839T1 (en) | 1993-11-19 | 2004-04-15 | Cross Med Prod Inc | MOUNTING ROD SEAT WITH SLIDING LOCK |
US5514180A (en) | 1994-01-14 | 1996-05-07 | Heggeness; Michael H. | Prosthetic intervertebral devices |
US5458642A (en) | 1994-01-18 | 1995-10-17 | Beer; John C. | Synthetic intervertebral disc |
FR2716616A1 (en) | 1994-02-25 | 1995-09-01 | Lenfant Jean Pierre | Pedicular bone screw e.g. for vertebral reinforcement operation |
CA2551185C (en) | 1994-03-28 | 2007-10-30 | Sdgi Holdings, Inc. | Apparatus and method for anterior spinal stabilization |
FR2718946B1 (en) | 1994-04-25 | 1996-09-27 | Soprane Sa | Flexible rod for lumbosacral osteosynthesis fixator. |
US5888220A (en) | 1994-05-06 | 1999-03-30 | Advanced Bio Surfaces, Inc. | Articulating joint repair |
AU2621295A (en) | 1994-05-24 | 1995-12-18 | Smith & Nephew Plc | Intervertebral disc implant |
FR2721501B1 (en) | 1994-06-24 | 1996-08-23 | Fairant Paulette | Prostheses of the vertebral articular facets. |
US5498263A (en) | 1994-06-28 | 1996-03-12 | Acromed Corporation | Transverse connector for spinal column corrective devices |
US5980522A (en) | 1994-07-22 | 1999-11-09 | Koros; Tibor | Expandable spinal implants |
FR2722980B1 (en) | 1994-07-26 | 1996-09-27 | Samani Jacques | INTERTEPINOUS VERTEBRAL IMPLANT |
US7494507B2 (en) | 2000-01-30 | 2009-02-24 | Diamicron, Inc. | Articulating diamond-surfaced spinal implants |
RU2085145C1 (en) | 1994-09-05 | 1997-07-27 | Нижегородский государственный научно-исследовательский институт травматологии и ортопедии | Apparatus for surgical treatment of vertebral column deformation |
EP0700671B1 (en) | 1994-09-08 | 2001-08-08 | Stryker Technologies Corporation | Hydrogel intervertebral disc nucleus |
US5824093A (en) | 1994-10-17 | 1998-10-20 | Raymedica, Inc. | Prosthetic spinal disc nucleus |
US5567356A (en) | 1994-11-07 | 1996-10-22 | Monsanto Company | Emulsion-polymerization process and electrically-conductive polyaniline salts |
US5674296A (en) | 1994-11-14 | 1997-10-07 | Spinal Dynamics Corporation | Human spinal disc prosthesis |
FR2728159B1 (en) | 1994-12-16 | 1997-06-27 | Tornier Sa | ELASTIC DISC PROSTHESIS |
US5665122A (en) * | 1995-01-31 | 1997-09-09 | Kambin; Parviz | Expandable intervertebral cage and surgical method |
US5860973A (en) | 1995-02-27 | 1999-01-19 | Michelson; Gary Karlin | Translateral spinal implant |
FR2731344B1 (en) | 1995-03-06 | 1997-08-22 | Dimso Sa | SPINAL INSTRUMENTATION ESPECIALLY FOR A ROD |
DE19509331C2 (en) | 1995-03-15 | 1998-01-15 | Juergen Harms | Element for stabilizing the cervical vertebrae |
DE19509332C1 (en) | 1995-03-15 | 1996-08-14 | Harms Juergen | Anchoring element |
US5571191A (en) | 1995-03-16 | 1996-11-05 | Fitz; William R. | Artificial facet joint |
US5782919A (en) | 1995-03-27 | 1998-07-21 | Sdgi Holdings, Inc. | Interbody fusion device and method for restoration of normal spinal anatomy |
US5882350A (en) | 1995-04-13 | 1999-03-16 | Fastenetix, Llc | Polyaxial pedicle screw having a threaded and tapered compression locking mechanism |
DE19519101B4 (en) | 1995-05-24 | 2009-04-23 | Harms, Jürgen, Prof. Dr. | Height adjustable vertebral body replacement |
US5562663A (en) | 1995-06-07 | 1996-10-08 | Danek Medical, Inc. | Implant interconnection mechanism |
US5683391A (en) | 1995-06-07 | 1997-11-04 | Danek Medical, Inc. | Anterior spinal instrumentation and method for implantation and revision |
FR2735351B1 (en) | 1995-06-13 | 1997-09-12 | Sofamor | IMPLANT FOR THE SURGICAL TREATMENT OF A VERTEBRAL ISTHMIC FRACTURE |
ES2278091T3 (en) | 1995-11-08 | 2007-08-01 | Zimmer Gmbh | DEVICE FOR INTRODUCING AN IMPLANT, IN PARTICULAR AN INTERVERTEBRAL PROTESIS. |
FR2745706A1 (en) | 1996-03-05 | 1997-09-12 | Option Sa | Prosthetic vertebral support device |
US5800550A (en) | 1996-03-13 | 1998-09-01 | Sertich; Mario M. | Interbody fusion cage |
US5683465A (en) | 1996-03-18 | 1997-11-04 | Shinn; Gary Lee | Artificial intervertebral disk prosthesis |
AU5521496A (en) | 1996-03-27 | 1997-10-17 | Lubos Rehak | The device for the correction of spinal deformities |
US5653763A (en) | 1996-03-29 | 1997-08-05 | Fastenetix, L.L.C. | Intervertebral space shape conforming cage device |
US5785647A (en) | 1996-07-31 | 1998-07-28 | United States Surgical Corporation | Surgical instruments useful for spinal surgery |
US5964807A (en) | 1996-08-08 | 1999-10-12 | Trustees Of The University Of Pennsylvania | Compositions and methods for intervertebral disc reformation |
FR2753368B1 (en) | 1996-09-13 | 1999-01-08 | Chauvin Jean Luc | EXPANSIONAL OSTEOSYNTHESIS CAGE |
US5782832A (en) | 1996-10-01 | 1998-07-21 | Surgical Dynamics, Inc. | Spinal fusion implant and method of insertion thereof |
US5863293A (en) | 1996-10-18 | 1999-01-26 | Spinal Innovations | Spinal implant fixation assembly |
US6416515B1 (en) | 1996-10-24 | 2002-07-09 | Spinal Concepts, Inc. | Spinal fixation system |
EP0934026B1 (en) | 1996-10-24 | 2009-07-15 | Zimmer Spine Austin, Inc | Apparatus for spinal fixation |
US5895428A (en) | 1996-11-01 | 1999-04-20 | Berry; Don | Load bearing spinal joint implant |
US5827328A (en) | 1996-11-22 | 1998-10-27 | Buttermann; Glenn R. | Intervertebral prosthetic device |
US5776135A (en) | 1996-12-23 | 1998-07-07 | Third Millennium Engineering, Llc | Side mounted polyaxial pedicle screw |
US5961554A (en) | 1996-12-31 | 1999-10-05 | Janson; Frank S | Intervertebral spacer |
US6712819B2 (en) | 1998-10-20 | 2004-03-30 | St. Francis Medical Technologies, Inc. | Mating insertion instruments for spinal implants and methods of use |
US5861041A (en) | 1997-04-07 | 1999-01-19 | Arthit Sitiso | Intervertebral disk prosthesis and method of making the same |
US5800549A (en) | 1997-04-30 | 1998-09-01 | Howmedica Inc. | Method and apparatus for injecting an elastic spinal implant |
US6045579A (en) | 1997-05-01 | 2000-04-04 | Spinal Concepts, Inc. | Adjustable height fusion device |
US6641614B1 (en) | 1997-05-01 | 2003-11-04 | Spinal Concepts, Inc. | Multi-variable-height fusion device |
FR2762778B1 (en) | 1997-05-02 | 1999-07-16 | Stryker France Sa | IMPLANT, IN PARTICULAR FOR THE REPLACEMENT OF A VERTEBRAL BODY IN RACHIS SURGERY |
US5810819A (en) | 1997-05-15 | 1998-09-22 | Spinal Concepts, Inc. | Polyaxial pedicle screw having a compression locking rod gripping mechanism |
US5785711A (en) | 1997-05-15 | 1998-07-28 | Third Millennium Engineering, Llc | Polyaxial pedicle screw having a through bar clamp locking mechanism |
US6022376A (en) | 1997-06-06 | 2000-02-08 | Raymedica, Inc. | Percutaneous prosthetic spinal disc nucleus and method of manufacture |
US5893889A (en) | 1997-06-20 | 1999-04-13 | Harrington; Michael | Artificial disc |
GB9713330D0 (en) | 1997-06-25 | 1997-08-27 | Bridport Gundry Plc | Surgical implant |
GB9714580D0 (en) | 1997-07-10 | 1997-09-17 | Wardlaw Douglas | Prosthetic intervertebral disc nucleus |
US5928243A (en) | 1997-07-16 | 1999-07-27 | Spinal Concepts, Inc. | Pedicle probe and depth gage |
US6030389A (en) | 1997-08-04 | 2000-02-29 | Spinal Concepts, Inc. | System and method for stabilizing the human spine with a bone plate |
US6146421A (en) | 1997-08-04 | 2000-11-14 | Gordon, Maya, Roberts And Thomas, Number 1, Llc | Multiple axis intervertebral prosthesis |
IL134387A0 (en) | 1997-08-04 | 2001-04-30 | Gordon Maya Robert & Thomas Nu | Multiple axis intervertebral prosthesis |
US6454769B2 (en) | 1997-08-04 | 2002-09-24 | Spinal Concepts, Inc. | System and method for stabilizing the human spine with a bone plate |
WO1999007312A1 (en) | 1997-08-06 | 1999-02-18 | Synthes Ag Chur | Intervertebral implant whereof the parts can be spaced |
US5964769A (en) | 1997-08-26 | 1999-10-12 | Spinal Concepts, Inc. | Surgical cable system and method |
US6053921A (en) | 1997-08-26 | 2000-04-25 | Spinal Concepts, Inc. | Surgical cable system and method |
US5865848A (en) | 1997-09-12 | 1999-02-02 | Artifex, Ltd. | Dynamic intervertebral spacer and method of use |
US5824094A (en) | 1997-10-17 | 1998-10-20 | Acromed Corporation | Spinal disc |
US6139579A (en) | 1997-10-31 | 2000-10-31 | Depuy Motech Acromed, Inc. | Spinal disc |
US5888226A (en) | 1997-11-12 | 1999-03-30 | Rogozinski; Chaim | Intervertebral prosthetic disc |
FR2771280B1 (en) | 1997-11-26 | 2001-01-26 | Albert P Alby | RESILIENT VERTEBRAL CONNECTION DEVICE |
US5899941A (en) | 1997-12-09 | 1999-05-04 | Chubu Bearing Kabushiki Kaisha | Artificial intervertebral disk |
US6162252A (en) | 1997-12-12 | 2000-12-19 | Depuy Acromed, Inc. | Artificial spinal disc |
US6214049B1 (en) | 1999-01-14 | 2001-04-10 | Comfort Biomedical, Inc. | Method and apparatus for augmentating osteointegration of prosthetic implant devices |
DE19804765C2 (en) | 1998-02-06 | 2000-09-28 | Biedermann Motech Gmbh | Placeholder with adjustable axial length |
DE19807236C2 (en) * | 1998-02-20 | 2000-06-21 | Biedermann Motech Gmbh | Intervertebral implant |
US6045552A (en) | 1998-03-18 | 2000-04-04 | St. Francis Medical Technologies, Inc. | Spine fixation plate system |
US6428541B1 (en) | 1998-04-09 | 2002-08-06 | Sdgi Holdings, Inc. | Method and instrumentation for vertebral interbody fusion |
US6019792A (en) | 1998-04-23 | 2000-02-01 | Cauthen Research Group, Inc. | Articulating spinal implant |
US6679915B1 (en) | 1998-04-23 | 2004-01-20 | Sdgi Holdings, Inc. | Articulating spinal implant |
JP2002512079A (en) | 1998-04-23 | 2002-04-23 | コーゼン リサーチ グループ インク. | Articulated spinal implant |
US6290724B1 (en) | 1998-05-27 | 2001-09-18 | Nuvasive, Inc. | Methods for separating and stabilizing adjacent vertebrae |
US6132465A (en) | 1998-06-04 | 2000-10-17 | Raymedica, Inc. | Tapered prosthetic spinal disc nucleus |
US6126689A (en) | 1998-06-15 | 2000-10-03 | Expanding Concepts, L.L.C. | Collapsible and expandable interbody fusion device |
US6296664B1 (en) | 1998-06-17 | 2001-10-02 | Surgical Dynamics, Inc. | Artificial intervertebral disc |
US6136031A (en) | 1998-06-17 | 2000-10-24 | Surgical Dynamics, Inc. | Artificial intervertebral disc |
US6231609B1 (en) | 1998-07-09 | 2001-05-15 | Hamid M. Mehdizadeh | Disc replacement prosthesis |
ATE363877T1 (en) | 1998-07-22 | 2007-06-15 | Warsaw Orthopedic Inc | SCREWED CYLINDRICAL MULTIDISCOID SINGLE OR MULTIPLE NETWORK PLATE PROSTHESIS |
PT1100417E (en) | 1998-08-03 | 2004-08-31 | Synthes Ag | ALOGENIC IMPLANT INTERVERTEBRAL DILATADOR |
US6099531A (en) | 1998-08-20 | 2000-08-08 | Bonutti; Peter M. | Changing relationship between bones |
FR2782632B1 (en) | 1998-08-28 | 2000-12-29 | Materiel Orthopedique En Abreg | EXPANSIBLE INTERSOMATIC FUSION CAGE |
US7029473B2 (en) | 1998-10-20 | 2006-04-18 | St. Francis Medical Technologies, Inc. | Deflectable spacer for use as an interspinous process implant and method |
US6113637A (en) | 1998-10-22 | 2000-09-05 | Sofamor Danek Holdings, Inc. | Artificial intervertebral joint permitting translational and rotational motion |
US6039763A (en) | 1998-10-27 | 2000-03-21 | Disc Replacement Technologies, Inc. | Articulating spinal disc prosthesis |
US6174311B1 (en) | 1998-10-28 | 2001-01-16 | Sdgi Holdings, Inc. | Interbody fusion grafts and instrumentation |
US6537320B1 (en) | 1998-10-30 | 2003-03-25 | Gary K. Michelson | Self-broaching, rotatable, push-in interbody spinal fusion implant and method for deployment thereof |
FR2787018B1 (en) | 1998-12-11 | 2001-03-02 | Dimso Sa | INTERVERTEBRAL DISC PROSTHESIS WITH LIQUID ENCLOSURE |
US6159244A (en) | 1999-07-30 | 2000-12-12 | Suddaby; Loubert | Expandable variable angle intervertebral fusion implant |
US6123707A (en) | 1999-01-13 | 2000-09-26 | Spinal Concepts, Inc. | Reduction instrument |
US6102950A (en) | 1999-01-19 | 2000-08-15 | Vaccaro; Alex | Intervertebral body fusion device |
US6146422A (en) | 1999-01-25 | 2000-11-14 | Lawson; Kevin Jon | Prosthetic nucleus replacement for surgical reconstruction of intervertebral discs and treatment method |
US6368350B1 (en) | 1999-03-11 | 2002-04-09 | Sulzer Spine-Tech Inc. | Intervertebral disc prosthesis and method |
US6110210A (en) | 1999-04-08 | 2000-08-29 | Raymedica, Inc. | Prosthetic spinal disc nucleus having selectively coupled bodies |
US6442814B1 (en) | 1999-04-23 | 2002-09-03 | Spinal Concepts, Inc. | Apparatus for manufacturing a bone dowel |
US6558423B1 (en) | 1999-05-05 | 2003-05-06 | Gary K. Michelson | Interbody spinal fusion implants with multi-lock for locking opposed screws |
US6607530B1 (en) | 1999-05-10 | 2003-08-19 | Highgate Orthopedics, Inc. | Systems and methods for spinal fixation |
US6214050B1 (en) | 1999-05-11 | 2001-04-10 | Donald R. Huene | Expandable implant for inter-bone stabilization and adapted to extrude osteogenic material, and a method of stabilizing bones while extruding osteogenic material |
US6419704B1 (en) | 1999-10-08 | 2002-07-16 | Bret Ferree | Artificial intervertebral disc replacement methods and apparatus |
US6491724B1 (en) | 1999-08-13 | 2002-12-10 | Bret Ferree | Spinal fusion cage with lordosis correction |
US6371990B1 (en) | 1999-10-08 | 2002-04-16 | Bret A. Ferree | Annulus fibrosis augmentation methods and apparatus |
EP1185221B1 (en) | 1999-06-04 | 2005-03-23 | SDGI Holdings, Inc. | Artificial disc implant |
US20020128714A1 (en) | 1999-06-04 | 2002-09-12 | Mark Manasas | Orthopedic implant and method of making metal articles |
US6520996B1 (en) | 1999-06-04 | 2003-02-18 | Depuy Acromed, Incorporated | Orthopedic implant |
WO2001001895A1 (en) | 1999-07-02 | 2001-01-11 | Petrus Besselink | Reinforced expandable cage |
US6936071B1 (en) | 1999-07-02 | 2005-08-30 | Spine Solutions, Inc. | Intervertebral implant |
WO2002009626A1 (en) | 1999-07-26 | 2002-02-07 | Advanced Prosthetic Technologies, Inc. | Improved spinal surgical prosthesis |
US6454806B1 (en) | 1999-07-26 | 2002-09-24 | Advanced Prosthetic Technologies, Inc. | Spinal surgical prosthesis |
FR2796828B1 (en) | 1999-07-27 | 2001-10-19 | Dev Sed Soc Et | IMPLANTABLE INTERVERTEBRAL CONNECTION DEVICE |
EP1779815A3 (en) | 1999-09-14 | 2007-06-27 | Spine Solutions Inc. | Insert instrument for an implant between vertebrae |
WO2001022893A1 (en) | 1999-09-27 | 2001-04-05 | Blackstone Medical, Inc. | A surgical screw system and related methods |
US6554834B1 (en) | 1999-10-07 | 2003-04-29 | Stryker Spine | Slotted head pedicle screw assembly |
US7060100B2 (en) | 1999-10-08 | 2006-06-13 | Ferree Bret A | Artificial disc and joint replacements with modular cushioning components |
FR2799638B1 (en) | 1999-10-14 | 2002-08-16 | Fred Zacouto | FIXATOR AND VERTEBRAL JOINT |
US6206924B1 (en) | 1999-10-20 | 2001-03-27 | Interpore Cross Internat | Three-dimensional geometric bio-compatible porous engineered structure for use as a bone mass replacement or fusion augmentation device |
US6500180B1 (en) | 1999-10-20 | 2002-12-31 | Sdgi Holdings, Inc. | Methods and instrumentation for distraction of a disc space |
US6830570B1 (en) | 1999-10-21 | 2004-12-14 | Sdgi Holdings, Inc. | Devices and techniques for a posterior lateral disc space approach |
WO2001028469A2 (en) | 1999-10-21 | 2001-04-26 | Sdgi Holdings, Inc. | Devices and techniques for a posterior lateral disc space approach |
US6974478B2 (en) | 1999-10-22 | 2005-12-13 | Archus Orthopedics, Inc. | Prostheses, systems and methods for replacement of natural facet joints with artificial facet joint surfaces |
US20050027361A1 (en) | 1999-10-22 | 2005-02-03 | Reiley Mark A. | Facet arthroplasty devices and methods |
EP1223872B2 (en) | 1999-10-22 | 2007-09-26 | Archus Orthopedics Inc. | Facet arthroplasty devices |
US6811567B2 (en) | 1999-10-22 | 2004-11-02 | Archus Orthopedics Inc. | Facet arthroplasty devices and methods |
FR2799949B1 (en) | 1999-10-22 | 2002-06-28 | Abder Benazza | SPINAL OSTETHOSYNTHESIS DEVICE |
US6592624B1 (en) | 1999-11-24 | 2003-07-15 | Depuy Acromed, Inc. | Prosthetic implant element |
US6395034B1 (en) | 1999-11-24 | 2002-05-28 | Loubert Suddaby | Intervertebral disc prosthesis |
AU778410B2 (en) | 1999-12-01 | 2004-12-02 | Henry Graf | Intervertebral stabilising device |
US6648915B2 (en) | 1999-12-23 | 2003-11-18 | John A. Sazy | Intervertebral cage and method of use |
US6447512B1 (en) | 2000-01-06 | 2002-09-10 | Spinal Concepts, Inc. | Instrument and method for implanting an interbody fusion device |
US6331179B1 (en) | 2000-01-06 | 2001-12-18 | Spinal Concepts, Inc. | System and method for stabilizing the human spine with a bone plate |
EP1645248B8 (en) | 2000-02-04 | 2010-06-16 | Warsaw Orthopedic, Inc. | Expandable interbody spinal fusion implant having pivotally attached blocker |
US6500205B1 (en) | 2000-04-19 | 2002-12-31 | Gary K. Michelson | Expandable threaded arcuate interbody spinal fusion implant with cylindrical configuration during insertion |
US6716247B2 (en) | 2000-02-04 | 2004-04-06 | Gary K. Michelson | Expandable push-in interbody spinal fusion implant |
DE60119279T2 (en) | 2000-02-04 | 2007-03-08 | Warsaw Orthopedic, Inc., Minneapolis | EXPANDABLE INSERT INTERMEDIATE FUSION IMPLANT |
US6814756B1 (en) | 2000-02-04 | 2004-11-09 | Gary K. Michelson | Expandable threaded arcuate interbody spinal fusion implant with lordotic configuration during insertion |
DE60030404T2 (en) | 2000-02-22 | 2007-02-22 | Lucent Technologies Inc. | Procedures for passing on real-time connections in wireless communication systems |
US6565566B1 (en) | 2000-03-22 | 2003-05-20 | Spinal Concepts, Inc. | Sacral screw assembly and method |
US6402750B1 (en) | 2000-04-04 | 2002-06-11 | Spinlabs, Llc | Devices and methods for the treatment of spinal disorders |
US6821298B1 (en) | 2000-04-18 | 2004-11-23 | Roger P. Jackson | Anterior expandable spinal fusion cage system |
US6482234B1 (en) | 2000-04-26 | 2002-11-19 | Pearl Technology Holdings, Llc | Prosthetic spinal disc |
DE10026172A1 (en) | 2000-05-26 | 2001-11-29 | Roche Diagnostics Gmbh | Body fluid withdrawal system |
US6533817B1 (en) | 2000-06-05 | 2003-03-18 | Raymedica, Inc. | Packaged, partially hydrated prosthetic disc nucleus |
AU2001268749A1 (en) | 2000-06-05 | 2001-12-17 | Tensegra, Inc. | Orthopedic implant and method of making metal articles |
US6579318B2 (en) | 2000-06-12 | 2003-06-17 | Ortho Development Corporation | Intervertebral spacer |
FR2810874B1 (en) | 2000-06-30 | 2002-08-23 | Materiel Orthopedique En Abreg | IMPLANT FOR OSTEOSYNTHESIS DEVICE COMPRISING A PART FOR BONE ANCHORING AND A BODY FOR FIXING ON A ROD |
US6447545B1 (en) | 2000-07-01 | 2002-09-10 | George W. Bagby | Self-aligning bone implant |
US6482207B1 (en) | 2000-07-13 | 2002-11-19 | Fastenetix, Llc | Efficient assembling modular locking pedicle screw |
US6610093B1 (en) | 2000-07-28 | 2003-08-26 | Perumala Corporation | Method and apparatus for stabilizing adjacent vertebrae |
US6626905B1 (en) | 2000-08-02 | 2003-09-30 | Sulzer Spine-Tech Inc. | Posterior oblique lumbar arthrodesis |
US6500206B1 (en) | 2000-09-15 | 2002-12-31 | Donald W. Bryan | Instruments for inserting spinal vertebral implant |
US20080177310A1 (en) | 2000-10-20 | 2008-07-24 | Archus Orthopedics, Inc. | Facet arthroplasty devices and methods |
US6733531B1 (en) | 2000-10-20 | 2004-05-11 | Sdgi Holdings, Inc. | Anchoring devices and implants for intervertebral disc augmentation |
US6648893B2 (en) | 2000-10-27 | 2003-11-18 | Blackstone Medical, Inc. | Facet fixation devices |
US6582467B1 (en) | 2000-10-31 | 2003-06-24 | Vertelink Corporation | Expandable fusion cage |
US6666891B2 (en) | 2000-11-13 | 2003-12-23 | Frank H. Boehm, Jr. | Device and method for lumbar interbody fusion |
US6579319B2 (en) | 2000-11-29 | 2003-06-17 | Medicinelodge, Inc. | Facet joint replacement |
US6454807B1 (en) | 2000-11-30 | 2002-09-24 | Roger P. Jackson | Articulated expandable spinal fusion cage system |
US6773460B2 (en) | 2000-12-05 | 2004-08-10 | Roger P. Jackson | Anterior variable expandable fusion cage |
FR2817462B1 (en) | 2000-12-05 | 2003-08-08 | Stryker Spine Sa | IN SITU INTERSOMATIC SPINAL IMPLANT WITH HARD PASSAGE POINTS |
US6419703B1 (en) | 2001-03-01 | 2002-07-16 | T. Wade Fallin | Prosthesis for the replacement of a posterior element of a vertebra |
US6565605B2 (en) | 2000-12-13 | 2003-05-20 | Medicinelodge, Inc. | Multiple facet joint replacement |
US6413259B1 (en) | 2000-12-14 | 2002-07-02 | Blackstone Medical, Inc | Bone plate assembly including a screw retaining member |
US6743257B2 (en) | 2000-12-19 | 2004-06-01 | Cortek, Inc. | Dynamic implanted intervertebral spacer |
US6666870B2 (en) | 2001-01-05 | 2003-12-23 | Robert A Dixon | Method utilizing chemical bonding to improve the bone screw fixation interface |
US6936070B1 (en) | 2001-01-17 | 2005-08-30 | Nabil L. Muhanna | Intervertebral disc prosthesis and methods of implantation |
ATE384500T1 (en) | 2001-02-04 | 2008-02-15 | Warsaw Orthopedic Inc | INSTRUMENTS FOR INSERTING AND POSITIONING AN EXPANDABLE INTERVERBEL FUSION IMPLANT |
US6989032B2 (en) | 2001-07-16 | 2006-01-24 | Spinecore, Inc. | Artificial intervertebral disc |
US6451021B1 (en) | 2001-02-15 | 2002-09-17 | Third Millennium Engineering, Llc | Polyaxial pedicle screw having a rotating locking element |
US7604664B2 (en) | 2001-07-16 | 2009-10-20 | Spinecore, Inc. | Spinal baseplates with ball joint coupling and a retaining member |
US6896680B2 (en) | 2001-03-01 | 2005-05-24 | Gary K. Michelson | Arcuate dynamic lordotic guard with movable extensions for creating an implantation space posteriorly in the lumbar spine |
US7090698B2 (en) | 2001-03-02 | 2006-08-15 | Facet Solutions | Method and apparatus for spine joint replacement |
US6595998B2 (en) | 2001-03-08 | 2003-07-22 | Spinewave, Inc. | Tissue distraction device |
US6478822B1 (en) | 2001-03-20 | 2002-11-12 | Spineco, Inc. | Spherical spinal implant |
US6802844B2 (en) | 2001-03-26 | 2004-10-12 | Nuvasive, Inc | Spinal alignment apparatus and methods |
US7128760B2 (en) | 2001-03-27 | 2006-10-31 | Warsaw Orthopedic, Inc. | Radially expanding interbody spinal fusion implants, instrumentation, and methods of insertion |
US6368351B1 (en) | 2001-03-27 | 2002-04-09 | Bradley J. Glenn | Intervertebral space implant for use in spinal fusion procedures |
FR2824261B1 (en) | 2001-05-04 | 2004-05-28 | Ldr Medical | INTERVERTEBRAL DISC PROSTHESIS AND IMPLEMENTATION METHOD AND TOOLS |
US6558424B2 (en) | 2001-06-28 | 2003-05-06 | Depuy Acromed | Modular anatomic fusion device |
US6468310B1 (en) | 2001-07-16 | 2002-10-22 | Third Millennium Engineering, Llc | Intervertebral spacer device having a wave washer force restoring element |
US7118599B2 (en) | 2001-07-16 | 2006-10-10 | Spinecore, Inc. | Artificial intervertebral disc |
US7153310B2 (en) | 2001-07-16 | 2006-12-26 | Spinecore, Inc. | Vertebral bone distraction instruments |
DE10138079B4 (en) | 2001-08-03 | 2004-02-12 | Biedermann Motech Gmbh | Placeholder with variable axial length |
US6375682B1 (en) | 2001-08-06 | 2002-04-23 | Lewis W. Fleischmann | Collapsible, rotatable and expandable spinal hydraulic prosthetic device |
AU2002330146B2 (en) | 2001-09-28 | 2007-10-18 | Zimmer Spine, Inc. | Skeletal stabilization implant |
US6648917B2 (en) | 2001-10-17 | 2003-11-18 | Medicinelodge, Inc. | Adjustable bone fusion implant and method |
US8025684B2 (en) | 2001-11-09 | 2011-09-27 | Zimmer Spine, Inc. | Instruments and methods for inserting a spinal implant |
FR2832054B1 (en) | 2001-11-15 | 2004-09-10 | Rene Louis | POSTERIOR VERTEBRAL JOINT PROSTHESIS |
US7025787B2 (en) | 2001-11-26 | 2006-04-11 | Sdgi Holdings, Inc. | Implantable joint prosthesis and associated instrumentation |
US7052515B2 (en) | 2001-12-07 | 2006-05-30 | Simonson Rush E | Vertebral implant with dampening matrix adapted for posterior insertion |
US6572653B1 (en) | 2001-12-07 | 2003-06-03 | Rush E. Simonson | Vertebral implant adapted for posterior insertion |
US6736850B2 (en) | 2001-12-28 | 2004-05-18 | Spinal Concepts, Inc. | Vertebral pseudo arthrosis device and method |
US20040019353A1 (en) | 2002-02-01 | 2004-01-29 | Freid James M. | Spinal plate system for stabilizing a portion of a spine |
US7303564B2 (en) | 2002-02-01 | 2007-12-04 | Spinal Concepts, Inc. | Spinal plate extender system and method |
US6893464B2 (en) | 2002-03-05 | 2005-05-17 | The Regents Of The University Of California | Method and apparatus for providing an expandable spinal fusion cage |
CA2478311C (en) | 2002-03-11 | 2010-07-20 | Spinal Concepts, Inc. | Instrumentation and procedure for implanting spinal implant devices |
RU2303422C2 (en) | 2002-03-12 | 2007-07-27 | Сервитек Инк. | Intervertebral prosthesis and system of intervertebral prostheses, in peculiar case, for cervical department of vertebral column |
US6966910B2 (en) | 2002-04-05 | 2005-11-22 | Stephen Ritland | Dynamic fixation device and method of use |
US8696749B2 (en) | 2002-04-25 | 2014-04-15 | Blackstone Medical, Inc. | Artificial intervertebral disc |
US7338525B2 (en) | 2002-04-30 | 2008-03-04 | Ferree Bret A | Methods and apparatus for preventing the migration of intradiscal devices |
US8388684B2 (en) | 2002-05-23 | 2013-03-05 | Pioneer Signal Technology, Inc. | Artificial disc device |
US20030220643A1 (en) | 2002-05-24 | 2003-11-27 | Ferree Bret A. | Devices to prevent spinal extension |
EP1534194A2 (en) | 2002-06-26 | 2005-06-01 | Nuvasive, Inc. | Total disc replacement system and related methods |
US7192448B2 (en) | 2002-06-27 | 2007-03-20 | Ferree Bret A | Arthroplasty devices with resorbable component |
DE10236691B4 (en) | 2002-08-09 | 2005-12-01 | Biedermann Motech Gmbh | Dynamic stabilization device for bones, in particular for vertebrae |
US20040087947A1 (en) | 2002-08-28 | 2004-05-06 | Roy Lim | Minimally invasive expanding spacer and method |
US7044971B2 (en) | 2002-08-30 | 2006-05-16 | Loubert Suddaby | Lordotic fusion implant |
WO2004019828A1 (en) | 2002-09-02 | 2004-03-11 | Mathys Medizinaltechnik Ag | Intervertebral implant comprising a three-part articulation |
FR2844180B1 (en) | 2002-09-11 | 2005-08-05 | Spinevision | CONNECTING ELEMENT FOR THE DYNAMIC STABILIZATION OF A SPINAL FIXING SYSTEM AND SPINAL FASTENING SYSTEM COMPRISING SUCH A MEMBER |
US7018415B1 (en) | 2002-09-23 | 2006-03-28 | Sdgi Holdings, Inc. | Expandable spinal fusion device and methods of promoting spinal fusion |
US7214243B2 (en) | 2002-10-21 | 2007-05-08 | 3Hbfm, Llc | Intervertebral disk prosthesis |
US6966929B2 (en) | 2002-10-29 | 2005-11-22 | St. Francis Medical Technologies, Inc. | Artificial vertebral disk replacement implant with a spacer |
US7083649B2 (en) | 2002-10-29 | 2006-08-01 | St. Francis Medical Technologies, Inc. | Artificial vertebral disk replacement implant with translating pivot point |
US7273496B2 (en) | 2002-10-29 | 2007-09-25 | St. Francis Medical Technologies, Inc. | Artificial vertebral disk replacement implant with crossbar spacer and method |
US20040147928A1 (en) | 2002-10-30 | 2004-07-29 | Landry Michael E. | Spinal stabilization system using flexible members |
EP3222231A1 (en) | 2002-10-30 | 2017-09-27 | Zimmer Spine, Inc. | Spinal stabilization system insertion |
US20040133278A1 (en) | 2002-10-31 | 2004-07-08 | Marino James F. | Spinal disc implant |
US20040143332A1 (en) | 2002-10-31 | 2004-07-22 | Krueger David J. | Movable disc implant |
US20040106997A1 (en) | 2002-11-01 | 2004-06-03 | Lieberson Robert E. | Apparatus and method for creating a surgical channel |
US6723126B1 (en) | 2002-11-01 | 2004-04-20 | Sdgi Holdings, Inc. | Laterally expandable cage |
FR2846550B1 (en) | 2002-11-05 | 2006-01-13 | Ldr Medical | INTERVERTEBRAL DISC PROSTHESIS |
US6685742B1 (en) | 2002-11-12 | 2004-02-03 | Roger P. Jackson | Articulated anterior expandable spinal fusion cage system |
WO2004047689A1 (en) | 2002-11-21 | 2004-06-10 | Sdgi Holdings, Inc. | Systems and techniques for intravertebral spinal stablization with expandable devices |
US6974479B2 (en) | 2002-12-10 | 2005-12-13 | Sdgi Holdings, Inc. | System and method for blocking and/or retaining a prosthetic spinal implant |
US7204852B2 (en) | 2002-12-13 | 2007-04-17 | Spine Solutions, Inc. | Intervertebral implant, insertion tool and method of inserting same |
KR101004464B1 (en) | 2002-12-17 | 2010-12-31 | 신세스 게엠바하 | Intervertebral implant |
US7473276B2 (en) | 2002-12-17 | 2009-01-06 | Synthes (U.S.A.) | Intervertebral implant with joint parts mounted on roller bodies |
WO2004058098A2 (en) | 2002-12-17 | 2004-07-15 | Amedica Corporation | Total disc implant |
US7101398B2 (en) | 2002-12-31 | 2006-09-05 | Depuy Acromed, Inc. | Prosthetic facet joint ligament |
US20040167626A1 (en) | 2003-01-23 | 2004-08-26 | Geremakis Perry A. | Expandable artificial disc prosthesis |
US7828849B2 (en) | 2003-02-03 | 2010-11-09 | Warsaw Orthopedic, Inc. | Expanding interbody implant and articulating inserter and method |
US7235101B2 (en) | 2003-09-15 | 2007-06-26 | Warsaw Orthopedic, Inc. | Revisable prosthetic device |
US20040158254A1 (en) | 2003-02-12 | 2004-08-12 | Sdgi Holdings, Inc. | Instrument and method for milling a path into bone |
JP4598760B2 (en) | 2003-02-25 | 2010-12-15 | リットランド、ステファン | ADJUSTING ROD AND CONNECTOR DEVICE, AND ITS USING METHOD |
US7819801B2 (en) | 2003-02-27 | 2010-10-26 | Nuvasive, Inc. | Surgical access system and related methods |
US20050049590A1 (en) | 2003-03-07 | 2005-03-03 | Neville Alleyne | Spinal implant with securement spikes |
WO2004084742A1 (en) | 2003-03-24 | 2004-10-07 | Theken Surgical Llc | Spinal implant adjustment device |
US6981989B1 (en) | 2003-04-22 | 2006-01-03 | X-Pantu-Flex Drd Limited Liability Company | Rotatable and reversibly expandable spinal hydraulic prosthetic device |
US20050182401A1 (en) | 2003-05-02 | 2005-08-18 | Timm Jens P. | Systems and methods for spine stabilization including a dynamic junction |
WO2004098466A2 (en) | 2003-05-02 | 2004-11-18 | Smart Disc, Inc. | Artificial spinal disk |
US7713287B2 (en) | 2003-05-02 | 2010-05-11 | Applied Spine Technologies, Inc. | Dynamic spine stabilizer |
US20050171543A1 (en) | 2003-05-02 | 2005-08-04 | Timm Jens P. | Spine stabilization systems and associated devices, assemblies and methods |
US8652175B2 (en) | 2003-05-02 | 2014-02-18 | Rachiotek, Llc | Surgical implant devices and systems including a sheath member |
US7635379B2 (en) | 2003-05-02 | 2009-12-22 | Applied Spine Technologies, Inc. | Pedicle screw assembly with bearing surfaces |
US20050177164A1 (en) | 2003-05-02 | 2005-08-11 | Carmen Walters | Pedicle screw devices, systems and methods having a preloaded set screw |
US7615068B2 (en) | 2003-05-02 | 2009-11-10 | Applied Spine Technologies, Inc. | Mounting mechanisms for pedicle screws and related assemblies |
US7029475B2 (en) | 2003-05-02 | 2006-04-18 | Yale University | Spinal stabilization method |
US7291173B2 (en) | 2003-05-06 | 2007-11-06 | Aesculap Ii, Inc. | Artificial intervertebral disc |
US7608104B2 (en) | 2003-05-14 | 2009-10-27 | Archus Orthopedics, Inc. | Prostheses, tools and methods for replacement of natural facet joints with artifical facet joint surfaces |
US6997929B2 (en) | 2003-05-16 | 2006-02-14 | Spine Wave, Inc. | Tissue distraction device |
US6986771B2 (en) | 2003-05-23 | 2006-01-17 | Globus Medical, Inc. | Spine stabilization system |
DE10326517A1 (en) | 2003-06-12 | 2005-01-05 | Stratec Medical | Device for the dynamic stabilization of bones or bone fragments, in particular vertebrae |
FR2856587B1 (en) | 2003-06-26 | 2006-02-24 | Scient X | DISCRETE PROSTHESIS FOR CERVICAL VERTEBRATES WITH CONTROLLED DEBATMENT |
DE10330698B4 (en) | 2003-07-08 | 2005-05-25 | Aesculap Ag & Co. Kg | Intervertebral implant |
US20050021040A1 (en) | 2003-07-21 | 2005-01-27 | Rudolf Bertagnoli | Vertebral retainer-distracter and method of using same |
DE602004023039D1 (en) | 2003-07-23 | 2009-10-22 | Ebi Llc | Expandable intervertebral implant |
US7621956B2 (en) | 2003-07-31 | 2009-11-24 | Globus Medical, Inc. | Prosthetic spinal disc replacement |
US7153325B2 (en) | 2003-08-01 | 2006-12-26 | Ultra-Kinetics, Inc. | Prosthetic intervertebral disc and methods for using the same |
FR2858546B1 (en) | 2003-08-04 | 2006-04-28 | Spine Next Sa | INTERVERTEBRAL DISC PROSTHESIS |
WO2005016194A2 (en) | 2003-08-05 | 2005-02-24 | Flexuspine, Inc. | Artificial spinal unit assemblies |
US7909869B2 (en) | 2003-08-05 | 2011-03-22 | Flexuspine, Inc. | Artificial spinal unit assemblies |
US7316714B2 (en) | 2003-08-05 | 2008-01-08 | Flexuspine, Inc. | Artificial functional spinal unit assemblies |
US20060229729A1 (en) | 2003-08-05 | 2006-10-12 | Gordon Charles R | Expandable intervertebral implant for use with instrument |
US8052723B2 (en) | 2003-08-05 | 2011-11-08 | Flexuspine Inc. | Dynamic posterior stabilization systems and methods of use |
US7753958B2 (en) | 2003-08-05 | 2010-07-13 | Gordon Charles R | Expandable intervertebral implant |
US7204853B2 (en) | 2003-08-05 | 2007-04-17 | Flexuspine, Inc. | Artificial functional spinal unit assemblies |
US7137985B2 (en) | 2003-09-24 | 2006-11-21 | N Spine, Inc. | Marking and guidance method and system for flexible fixation of a spine |
US20050203513A1 (en) | 2003-09-24 | 2005-09-15 | Tae-Ahn Jahng | Spinal stabilization device |
US7763052B2 (en) | 2003-12-05 | 2010-07-27 | N Spine, Inc. | Method and apparatus for flexible fixation of a spine |
ES2325989T3 (en) | 2003-09-29 | 2009-09-28 | Synthes Gmbh | DEVICE FOR THE ELASTIC STABILIZATION OF THE VERTEBRAL BODIES. |
DE10348329B3 (en) | 2003-10-17 | 2005-02-17 | Biedermann Motech Gmbh | Rod-shaped element used in spinal column and accident surgery for connecting two bone-anchoring elements comprises a rigid section and an elastic section that are made in one piece |
US6966930B2 (en) | 2003-10-20 | 2005-11-22 | Impliant Ltd. | Facet prosthesis |
US7520899B2 (en) | 2003-11-05 | 2009-04-21 | Kyphon Sarl | Laterally insertable artificial vertebral disk replacement implant with crossbar spacer |
ES2287686T3 (en) | 2003-11-07 | 2007-12-16 | Impliant Ltd. | VERTEBRAL PROTESIS. |
US7083622B2 (en) | 2003-11-10 | 2006-08-01 | Simonson Peter M | Artificial facet joint and method |
US7289613B2 (en) | 2003-11-13 | 2007-10-30 | Metro One Telecommunications, Inc. | Technique for selecting a profile to use to service a call |
US7862586B2 (en) | 2003-11-25 | 2011-01-04 | Life Spine, Inc. | Spinal stabilization systems |
US20050154462A1 (en) | 2003-12-02 | 2005-07-14 | St. Francis Medical Technologies, Inc. | Laterally insertable artificial vertebral disk replacement implant with translating pivot point |
DE502004010737D1 (en) | 2003-12-09 | 2010-03-25 | Biedermann Motech Gmbh | Height-adjustable intervertebral implant |
US20050131406A1 (en) | 2003-12-15 | 2005-06-16 | Archus Orthopedics, Inc. | Polyaxial adjustment of facet joint prostheses |
DE10361772B4 (en) | 2003-12-31 | 2006-10-12 | Henning Kloss | Intervertebral disc implant |
US7550010B2 (en) | 2004-01-09 | 2009-06-23 | Warsaw Orthopedic, Inc. | Spinal arthroplasty device and method |
US7771479B2 (en) | 2004-01-09 | 2010-08-10 | Warsaw Orthopedic, Inc. | Dual articulating spinal device and method |
US7556651B2 (en) | 2004-01-09 | 2009-07-07 | Warsaw Orthopedic, Inc. | Posterior spinal device and method |
US20050171610A1 (en) | 2004-01-09 | 2005-08-04 | Sdgi Holdings, Inc. | Mobile bearing spinal device and method |
US7901459B2 (en) | 2004-01-09 | 2011-03-08 | Warsaw Orthopedic, Inc. | Split spinal device and method |
US7485146B1 (en) | 2004-03-08 | 2009-02-03 | Nuvasive, Inc. | Total disc replacement system and related methods |
ATE387165T1 (en) | 2004-03-08 | 2008-03-15 | Impliant Ltd | SPINAL PROSTHESIS |
US20050251261A1 (en) | 2004-05-05 | 2005-11-10 | Sdgi Holdings, Inc. | Artificial intervertebral disc for lateral insertion |
US7338527B2 (en) | 2004-05-11 | 2008-03-04 | Geoffrey Blatt | Artificial spinal disc, insertion tool, and method of insertion |
US7708760B2 (en) | 2004-05-27 | 2010-05-04 | Depuy Spine, Inc. | Tri-joint implant |
US7588578B2 (en) | 2004-06-02 | 2009-09-15 | Facet Solutions, Inc | Surgical measurement systems and methods |
US20060015100A1 (en) | 2004-06-23 | 2006-01-19 | Panjabi Manohar M | Spinal stabilization devices coupled by torsional member |
ES2398085T3 (en) | 2004-06-30 | 2013-03-13 | Synergy Disc Replacement Inc. | Artificial intervertebral disc |
US8172904B2 (en) | 2004-06-30 | 2012-05-08 | Synergy Disc Replacement, Inc. | Artificial spinal disc |
US7637914B2 (en) | 2004-08-04 | 2009-12-29 | Leslie Stern | Surgical base unit and retractor support mechanism |
US7854752B2 (en) | 2004-08-09 | 2010-12-21 | Theken Spine, Llc | System and method for dynamic skeletal stabilization |
US7780731B2 (en) | 2004-11-26 | 2010-08-24 | Spine Solutions, Inc. | Intervertebral implant |
US7547309B2 (en) | 2004-09-23 | 2009-06-16 | Spine Solutions, Inc. | Distractor for lumbar insertion instrument |
US7896906B2 (en) | 2004-12-30 | 2011-03-01 | Depuy Spine, Inc. | Artificial facet joint |
US8298235B2 (en) | 2004-09-30 | 2012-10-30 | Depuy Spine, Inc. | Instrument and method for the insertion and alignment of an intervertebral implant |
US20060085076A1 (en) | 2004-10-15 | 2006-04-20 | Manoj Krishna | Posterior spinal arthroplasty-development of a new posteriorly inserted artificial disc and an artificial facet joint |
US20060265074A1 (en) | 2004-10-21 | 2006-11-23 | Manoj Krishna | Posterior spinal arthroplasty-development of a new posteriorly inserted artificial disc, a new anteriorly inserted artifical disc and an artificial facet joint |
WO2006047587A2 (en) | 2004-10-25 | 2006-05-04 | Alphaspine, Inc. | Expandable intervertebral spacer method and apparatus |
US7566346B2 (en) | 2004-10-29 | 2009-07-28 | X-Spine Systems, Inc. | Prosthetic implant and method |
US20060095136A1 (en) * | 2004-11-03 | 2006-05-04 | Mcluen Design, Inc. | Bone fusion device |
US20060122701A1 (en) | 2004-11-23 | 2006-06-08 | Kiester P D | Posterior lumbar interbody fusion expandable cage with lordosis and method of deploying the same |
EP1814474B1 (en) | 2004-11-24 | 2011-09-14 | Samy Abdou | Devices for inter-vertebral orthopedic device placement |
US20060149372A1 (en) | 2004-12-17 | 2006-07-06 | Paxson Robert D | Artificial spinal disc |
US7491238B2 (en) | 2004-12-23 | 2009-02-17 | Impliant Ltd. | Adjustable spinal prosthesis |
KR20070101239A (en) | 2005-01-08 | 2007-10-16 | 알파스파인, 아이엔씨. | Modular disk device |
US20060167547A1 (en) | 2005-01-21 | 2006-07-27 | Loubert Suddaby | Expandable intervertebral fusion implants having hinged sidewalls |
US7361196B2 (en) | 2005-02-22 | 2008-04-22 | Stryker Spine | Apparatus and method for dynamic vertebral stabilization |
WO2006105437A2 (en) | 2005-03-31 | 2006-10-05 | Life Spine, Inc. | Expandable spinal interbody and intravertebral body devices |
CA2604144A1 (en) | 2005-04-11 | 2006-10-19 | Impliant Ltd. | Inserting anterior and posterior spinal prostheses |
US7674296B2 (en) | 2005-04-21 | 2010-03-09 | Globus Medical, Inc. | Expandable vertebral prosthesis |
GB0508678D0 (en) | 2005-04-28 | 2005-06-08 | Cope Aiden | Motion segment intervertebral disc prosthesis |
WO2006116851A1 (en) | 2005-05-02 | 2006-11-09 | Kinetic Spine Technologies Inc. | Intervertebral disc prosthesis |
US20060264937A1 (en) | 2005-05-04 | 2006-11-23 | White Patrick M | Mobile spine stabilization device |
US8323342B2 (en) | 2005-05-17 | 2012-12-04 | Schwab Frank J | Intervertebral implant |
JP5081822B2 (en) | 2005-07-14 | 2012-11-28 | スタウト メディカル グループ,エル.ピー. | Expandable support device and system |
US7811309B2 (en) | 2005-07-26 | 2010-10-12 | Applied Spine Technologies, Inc. | Dynamic spine stabilization device with travel-limiting functionality |
US7713288B2 (en) | 2005-08-03 | 2010-05-11 | Applied Spine Technologies, Inc. | Spring junction and assembly methods for spinal device |
US7699875B2 (en) | 2006-04-17 | 2010-04-20 | Applied Spine Technologies, Inc. | Spinal stabilization device with weld cap |
US8157806B2 (en) | 2005-10-12 | 2012-04-17 | Synthes Usa, Llc | Apparatus and methods for vertebral augmentation |
US7993376B2 (en) | 2005-09-29 | 2011-08-09 | Depuy Spine, Inc. | Methods of implanting a motion segment repair system |
WO2007044705A2 (en) | 2005-10-07 | 2007-04-19 | Abdou Samy M | Devices and methods for inter-verterbral orthopedic device placement |
US7517359B2 (en) | 2005-12-20 | 2009-04-14 | Sdgi Holdings, Inc. | Vertebral rod assemblies and methods |
US7918792B2 (en) | 2006-01-04 | 2011-04-05 | Depuy Spine, Inc. | Surgical retractor for use with minimally invasive spinal stabilization systems and methods of minimally invasive surgery |
US8556973B2 (en) | 2006-02-10 | 2013-10-15 | DePuy Synthes Products, LLC | Intervertebral disc prosthesis having multiple bearing surfaces |
US8118869B2 (en) | 2006-03-08 | 2012-02-21 | Flexuspine, Inc. | Dynamic interbody device |
US7766967B2 (en) | 2006-04-06 | 2010-08-03 | Warsaw Orthopedic Inc. | Intervertebral disc nucleus replacement implants and methods |
US7942905B2 (en) | 2006-04-20 | 2011-05-17 | Warsaw Orthopedic, Inc. | Vertebral stabilizer |
US8043379B2 (en) | 2006-04-21 | 2011-10-25 | Depuy Spine, Inc. | Disc prosthesis having remote flexion/extension center of rotation |
US8303660B1 (en) | 2006-04-22 | 2012-11-06 | Samy Abdou | Inter-vertebral disc prosthesis with variable rotational stop and methods of use |
US20070270838A1 (en) | 2006-05-08 | 2007-11-22 | Sdgi Holdings, Inc. | Dynamic spinal stabilization device with dampener |
US7905906B2 (en) | 2006-06-08 | 2011-03-15 | Disc Motion Technologies, Inc. | System and method for lumbar arthroplasty |
US7780676B2 (en) | 2006-07-11 | 2010-08-24 | Ebi, Llc | Intervertebral implantation apparatus |
US20080027547A1 (en) | 2006-07-27 | 2008-01-31 | Warsaw Orthopedic Inc. | Prosthetic device for spinal joint reconstruction |
US8425601B2 (en) | 2006-09-11 | 2013-04-23 | Warsaw Orthopedic, Inc. | Spinal stabilization devices and methods of use |
US8128700B2 (en) | 2006-09-13 | 2012-03-06 | Synthes Usa, Llc | Allograft intervertebral implant and method of manufacturing the same |
DE602006011762D1 (en) * | 2006-11-23 | 2010-03-04 | Biedermann Motech Gmbh | Expandable intervertebral implant |
US8105382B2 (en) * | 2006-12-07 | 2012-01-31 | Interventional Spine, Inc. | Intervertebral implant |
US20080161853A1 (en) | 2006-12-28 | 2008-07-03 | Depuy Spine, Inc. | Spine stabilization system with dynamic screw |
US9066811B2 (en) | 2007-01-19 | 2015-06-30 | Flexuspine, Inc. | Artificial functional spinal unit system and method for use |
WO2008134703A2 (en) | 2007-04-30 | 2008-11-06 | Globus Medical, Inc. | Flexible spine stabilization system |
CA2690038C (en) | 2007-05-31 | 2012-11-27 | Roger P. Jackson | Dynamic stabilization connecting member with pre-tensioned solid core |
US8864832B2 (en) | 2007-06-20 | 2014-10-21 | Hh Spinal Llc | Posterior total joint replacement |
US8313515B2 (en) | 2007-06-15 | 2012-11-20 | Rachiotek, Llc | Multi-level spinal stabilization system |
US20090076549A1 (en) | 2007-09-17 | 2009-03-19 | Warsaw Orthopedic, Inc. | Orthopedic implant system |
US20090088847A1 (en) | 2007-10-01 | 2009-04-02 | Manoj Krishna | Surgical instrument system |
US20090093846A1 (en) | 2007-10-04 | 2009-04-09 | Zimmer Spine Inc. | Pre-Curved Flexible Member For Providing Dynamic Stability To A Spine |
US8187330B2 (en) | 2007-10-22 | 2012-05-29 | Flexuspine, Inc. | Dampener system for a posterior stabilization system with a variable length elongated member |
US8162994B2 (en) | 2007-10-22 | 2012-04-24 | Flexuspine, Inc. | Posterior stabilization system with isolated, dual dampener systems |
US8523912B2 (en) | 2007-10-22 | 2013-09-03 | Flexuspine, Inc. | Posterior stabilization systems with shared, dual dampener systems |
US8182514B2 (en) | 2007-10-22 | 2012-05-22 | Flexuspine, Inc. | Dampener system for a posterior stabilization system with a fixed length elongated member |
US8267965B2 (en) | 2007-10-22 | 2012-09-18 | Flexuspine, Inc. | Spinal stabilization systems with dynamic interbody devices |
US8157844B2 (en) | 2007-10-22 | 2012-04-17 | Flexuspine, Inc. | Dampener system for a posterior stabilization system with a variable length elongated member |
US8911477B2 (en) | 2007-10-23 | 2014-12-16 | Roger P. Jackson | Dynamic stabilization member with end plate support and cable core extension |
US20090105764A1 (en) | 2007-10-23 | 2009-04-23 | Jackson Roger P | Dynamic stabilization member with fin support and solid core extension |
US20090177196A1 (en) | 2008-01-09 | 2009-07-09 | Applied Spine Technologies, Inc. | Medical Instrument For Rod Positioning |
WO2009092030A1 (en) | 2008-01-16 | 2009-07-23 | Life Spine, Inc. | Spinal inetrbody fusion cages providing variable anterior/posterior profieles |
US8147499B2 (en) | 2008-04-24 | 2012-04-03 | Spinecore, Inc. | Dynamic distractor |
US20100082109A1 (en) | 2008-09-22 | 2010-04-01 | Stout Medical Group, L.P. | Expandable intervertebral implant |
WO2010056895A1 (en) | 2008-11-12 | 2010-05-20 | Stout Medical Group, L.P. | Fixation device and method |
US20100191336A1 (en) | 2008-11-12 | 2010-07-29 | Stout Medical Group. L.P. | Fixation device and method |
US20100211176A1 (en) | 2008-11-12 | 2010-08-19 | Stout Medical Group, L.P. | Fixation device and method |
WO2010132841A1 (en) | 2009-05-14 | 2010-11-18 | Stout Medical Group, L.P. | Expandable support device and method of use |
US9084688B2 (en) | 2009-05-19 | 2015-07-21 | DePuy Synthes Products, Inc. | Dynamic trial implants |
US8475461B2 (en) | 2009-06-10 | 2013-07-02 | Life Spine, Inc. | Instruments for installing multi-section intervertebral spinal implants |
TW201103521A (en) | 2009-07-20 | 2011-02-01 | Wei-Zhen Hong | Spinal fusion device |
US8556979B2 (en) | 2009-10-15 | 2013-10-15 | Globus Medical, Inc. | Expandable fusion device and method of installation thereof |
US8062375B2 (en) | 2009-10-15 | 2011-11-22 | Globus Medical, Inc. | Expandable fusion device and method of installation thereof |
US8709086B2 (en) | 2009-10-15 | 2014-04-29 | Globus Medical, Inc. | Expandable fusion device and method of installation thereof |
US8685098B2 (en) | 2010-06-25 | 2014-04-01 | Globus Medical, Inc. | Expandable fusion device and method of installation thereof |
US8679183B2 (en) | 2010-06-25 | 2014-03-25 | Globus Medical | Expandable fusion device and method of installation thereof |
US9474625B2 (en) | 2010-09-03 | 2016-10-25 | Globus Medical, Inc | Expandable fusion device and method of installation thereof |
US8398713B2 (en) | 2010-09-03 | 2013-03-19 | Globus Medical, Inc. | Expandable fusion device and method of installation thereof |
US8491659B2 (en) | 2010-09-03 | 2013-07-23 | Globus Medical, Inc. | Expandable fusion device and method of installation thereof |
US9855151B2 (en) * | 2010-09-03 | 2018-01-02 | Globus Medical, Inc | Expandable fusion device and method of installation thereof |
US8632595B2 (en) | 2010-09-03 | 2014-01-21 | Globus Medical, Inc. | Expandable fusion device and method of installation thereof |
US8435298B2 (en) | 2010-09-03 | 2013-05-07 | Globus Medical, Inc. | Expandable fusion device and method of installation thereof |
US8518087B2 (en) * | 2011-03-10 | 2013-08-27 | Interventional Spine, Inc. | Method and apparatus for minimally invasive insertion of intervertebral implants |
US8388687B2 (en) | 2011-03-25 | 2013-03-05 | Flexuspine, Inc. | Interbody device insertion systems and methods |
US9526627B2 (en) | 2011-11-17 | 2016-12-27 | Exactech, Inc. | Expandable interbody device system and method |
US20130190876A1 (en) * | 2012-01-19 | 2013-07-25 | Warsaw Orthopedic, Inc. | Expandable interbody implant and methods of use |
US9233007B2 (en) | 2012-02-13 | 2016-01-12 | Blue Tip Biologics, Llc | Expandable self-anchoring interbody cage for orthopedic applications |
US9717601B2 (en) * | 2013-02-28 | 2017-08-01 | DePuy Synthes Products, Inc. | Expandable intervertebral implant, system, kit and method |
US11426290B2 (en) * | 2015-03-06 | 2022-08-30 | DePuy Synthes Products, Inc. | Expandable intervertebral implant, system, kit and method |
US20180161175A1 (en) * | 2016-12-14 | 2018-06-14 | DePuy Synthes Products, Inc. | Intervertebral implant inserter and related methods |
US10729560B2 (en) * | 2017-01-18 | 2020-08-04 | Neuropro Technologies, Inc. | Bone fusion system, device and method including an insertion instrument |
US9962272B1 (en) * | 2017-06-28 | 2018-05-08 | Amendia, Inc. | Intervertebral implant device with lordotic expansion |
US11752009B2 (en) * | 2021-04-06 | 2023-09-12 | Medos International Sarl | Expandable intervertebral fusion cage |
-
2014
- 2014-02-20 US US14/185,561 patent/US9492288B2/en active Active
-
2016
- 2016-11-15 US US15/351,943 patent/US20170281358A1/en not_active Abandoned
-
2018
- 2018-11-16 US US16/192,932 patent/US11369484B2/en active Active
-
2022
- 2022-06-09 US US17/836,741 patent/US11766341B2/en active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7217291B2 (en) * | 2003-12-08 | 2007-05-15 | St. Francis Medical Technologies, Inc. | System and method for replacing degenerated spinal disks |
US20120059470A1 (en) * | 2010-09-03 | 2012-03-08 | Mark Weiman | Expandable Fusion Device and Method of Installation Thereof |
WO2013023098A1 (en) * | 2011-08-09 | 2013-02-14 | Neuropro Spinal Jaxx Inc. | Bone fusion device, apparatus and method |
US20130204371A1 (en) * | 2011-08-09 | 2013-08-08 | Gary R. McLuen | Bone fusion device, system and method |
US9320610B2 (en) * | 2011-08-16 | 2016-04-26 | Stryker European Holdings I, Llc | Expandable implant |
US20140277500A1 (en) * | 2013-03-15 | 2014-09-18 | Neuropro Technologies, INC | Bodiless bone fusion device, apparatus and method |
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US11076968B2 (en) | 2012-12-13 | 2021-08-03 | Integrity Implants Inc. | Expandable scaffolding with a rigid, central beam |
US11234837B2 (en) | 2012-12-13 | 2022-02-01 | Integrity Implants Inc | Staged laterovertical expansion |
US10786366B2 (en) | 2012-12-13 | 2020-09-29 | Integrity Implants Inc. | Angled, rigid intervertebral scaffolding |
US10322014B2 (en) | 2013-09-09 | 2019-06-18 | Integrity Implants Inc. | Expandable trial with telescopic stabilizers |
US11253376B2 (en) | 2013-09-09 | 2022-02-22 | Integrity Implants Inc. | System for distracting and measuring an intervertebral space |
US10758368B2 (en) | 2015-01-20 | 2020-09-01 | Integrity Implants Inc. | Stabilized, 4 beam intervertebral scaffolding system |
US11918484B2 (en) | 2015-01-20 | 2024-03-05 | Integrity Implants Inc. | Methods of stabilizing an inter vertebral scaffolding |
US10052215B2 (en) * | 2016-06-29 | 2018-08-21 | Globus Medical, Inc. | Expandable fusion device and method of installation thereof |
US11717415B2 (en) | 2016-09-21 | 2023-08-08 | Integrity Implants Inc. | Scaffolding with locking expansion member |
US10912653B2 (en) | 2016-09-21 | 2021-02-09 | Integrity Implants Inc. | Stabilized laterovertically-expanding fusion cage systems with tensioner |
US10383743B2 (en) | 2016-09-21 | 2019-08-20 | Integrity Implants Inc. | Laterovertically-expanding fusion cage systems |
US11246716B2 (en) | 2016-10-18 | 2022-02-15 | Institute for Musculoskeletal Science and Education, Ltd. | Implant with deployable blades |
US11413157B2 (en) | 2016-10-25 | 2022-08-16 | Institute for Musculoskeletal Science and Education, Ltd. | Spinal fusion implant |
US11872143B2 (en) | 2016-10-25 | 2024-01-16 | Camber Spine Technologies, LLC | Spinal fusion implant |
US11331197B2 (en) | 2017-01-10 | 2022-05-17 | Integrity Implants Inc. | Spinal fusion device with staged expansion |
US11033401B2 (en) | 2017-01-10 | 2021-06-15 | Integrity Implants Inc. | Expandable intervertebral fusion device |
US10507116B2 (en) | 2017-01-10 | 2019-12-17 | Integrity Implants Inc. | Expandable intervertebral fusion device |
US11850165B2 (en) | 2017-07-24 | 2023-12-26 | Integrity Implants Inc. | Asymmetrically expandable cage |
US11224522B2 (en) | 2017-07-24 | 2022-01-18 | Integrity Implants Inc. | Surgical implant and related methods |
US10709578B2 (en) | 2017-08-25 | 2020-07-14 | Integrity Implants Inc. | Surgical biologics delivery system and related methods |
US11013610B2 (en) * | 2017-10-18 | 2021-05-25 | Spine Wave, Inc. | Expandable anterior lumbar interbody fusion device |
US11684484B2 (en) | 2018-03-01 | 2023-06-27 | Integrity Implants Inc. | Expandable fusion device with interdigitating fingers |
US11285018B2 (en) | 2018-03-01 | 2022-03-29 | Integrity Implants Inc. | Expandable fusion device with independent expansion systems |
US10849758B2 (en) | 2018-08-22 | 2020-12-01 | Institute for Musculoskeletal Science and Education, Ltd. | Spinal fusion implant |
DE102020200882A1 (en) | 2019-01-30 | 2020-07-30 | i-Pego GmbH | Inserter, adapter and display device for introducing a placeholder in spinal surgery |
USD946151S1 (en) | 2020-11-06 | 2022-03-15 | Mirus Llc | Medical device |
US11918489B2 (en) | 2021-04-02 | 2024-03-05 | Nuvasive Inc. | Expansion driver |
US11951016B2 (en) | 2021-05-11 | 2024-04-09 | Integrity Implants Inc. | Spinal fusion device with staged expansion |
Also Published As
Publication number | Publication date |
---|---|
US20220304821A1 (en) | 2022-09-29 |
US11369484B2 (en) | 2022-06-28 |
US20140236296A1 (en) | 2014-08-21 |
US20190321190A1 (en) | 2019-10-24 |
US9492288B2 (en) | 2016-11-15 |
US11766341B2 (en) | 2023-09-26 |
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