US20120078159A1 - Multi-lumen ventricular drainage catheter - Google Patents
Multi-lumen ventricular drainage catheter Download PDFInfo
- Publication number
- US20120078159A1 US20120078159A1 US12/894,111 US89411110A US2012078159A1 US 20120078159 A1 US20120078159 A1 US 20120078159A1 US 89411110 A US89411110 A US 89411110A US 2012078159 A1 US2012078159 A1 US 2012078159A1
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- Prior art keywords
- catheter
- aperture
- distal end
- enlarged opening
- lumens
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
- A61M27/002—Implant devices for drainage of body fluids from one part of the body to another
- A61M27/006—Cerebrospinal drainage; Accessories therefor, e.g. valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
- A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
- A61M25/0071—Multiple separate lumens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/04—General characteristics of the apparatus implanted
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0693—Brain, cerebrum
Definitions
- the present invention relates generally to a shunt and a catheter having a system for reducing the risk of blockage or obstruction of the catheter apertures and also increases the ease of revision surgery if the catheter is removed.
- Hydrocephalus is a neurological condition that is caused by the abnormal accumulation of cerebrospinal fluid (CSF) within the ventricles, or cavities, of the brain.
- CSF cerebrospinal fluid
- CSF is a clear, colorless fluid that is primarily produced by the choroid plexus and surrounds the brain and spinal cord.
- CSF constantly circulates through the ventricular system of the brain and is ultimately absorbed into the bloodstream.
- CSF aids in the protection of the brain and spinal cord. Because CSF keeps the brain and spinal cord buoyant, it acts as a protective cushion or “shock absorber” to prevent injuries to the central nervous system.
- Hydrocephalus which affects children and adults, arises when the normal drainage of CSF in the brain is blocked in some way.
- Such blockage can be caused by a number of factors, including, for example, genetic predisposition, intraventricular or intracranial hemorrhage, infections such as meningitis, head trauma, or the like. Blockage of the flow of CSF consequently creates an imbalance between the amount of CSF produced by the choroid plexus and the rate at which CSF is absorbed into the bloodstream, thereby increasing pressure on the brain, which causes the ventricles to enlarge.
- Hydrocephalus is most often treated by surgically inserting a shunt system that diverts the flow of CSF from the ventricle to another area of the body where the CSF can be absorbed as part of the circulatory system.
- Shunt systems come in a variety of models, and typically share similar functional components. These components include a ventricular catheter which is introduced through a burr hole in the skull and implanted in the patient's ventricle, a drainage catheter that carries the CSF to its ultimate drainage site, and optionally a flow-control mechanism, e.g., shunt valve, that regulates the one-way flow of CSF from the ventricle to the drainage site to maintain normal pressure within the ventricles.
- the ventricular catheter typically contains multiple holes or apertures positioned along the length of the ventricular catheter to allow the CSF to enter into the shunt system, as shown in FIGS. 6 and 7 .
- Shunting is considered one of the basic neurosurgical procedures, yet it has the highest complication rate.
- the most common complication with shunting is obstruction of the system. Although obstruction or clogging may occur at any point along the shunt system, it most frequently occurs at the ventricular end of the shunt system. While there are several ways that the ventricular catheter may become blocked or clogged, obstruction is typically caused by growth of tissue, such as the choroid plexus, around the catheter and into the apertures, as shown in FIG. 7 .
- the apertures of the ventricular catheter can also be obstructed by debris, bacteria, or coagulated blood.
- backflushing is a process that uses the CSF present in the shunt system to remove the obstructing matter. This process can be ineffective, however, due to the small size of the apertures of the ventricular catheter and due to the small amount of flushing liquid available in the shunt system.
- Other shunt systems have been designed to include a mechanism for flushing the shunt system.
- some shunt systems include a pumping device within the system which causes fluid in the system to flow with considerable pressure and velocity, thereby flushing the system.
- using a built-in mechanism to flush the shunt system can also fail to remove the obstruction due to factors such as the size of the apertures and the degree and extent to which the apertures have been clogged.
- Occluded ventricular catheters can also be repaired by cauterizing the catheter to remove blocking tissue, thereby reopening existing apertures that have become occluded.
- new apertures can be created in the catheter. These repairs, however, may be incapable of removing obstructions from the ventricular catheter depending on the location of the clogged apertures.
- the extent of tissue growth into and around the catheter can also preclude the creation of additional apertures, for example, in situations where the tissue growth covers a substantial portion of the ventricular catheter.
- Another disadvantage of creating new apertures to repair an occluded ventricular catheter is that this method fails to prevent or reduce the risk of repeated obstructions.
- occlusion is more often treated by replacing the catheter. Although this can be accomplished by removing the obstructed catheter from the ventricle, the growth of the choroid plexus and other tissues around the catheter and into the apertures can hinder removal and replacement of the catheter. Care must be exercised to avoid damage to the choroid plexus, which can cause severe injury to the patient, such as, for example, hemorrhaging. Not only do these procedures pose a significant risk of injury to the patient, they can also be very costly, especially when shunt obstruction is a recurring problem.
- the present invention provides a shunt that includes a housing having an inlet, an outlet and a flow control mechanism disposed within the housing.
- a ventricular catheter is connected to the inlet of the housing.
- the catheter has a longitudinal length, a proximal end, a distal end, and an inner lumen extending therethrough.
- the inner lumen of the catheter includes at least two lumens at the distal end and has only one lumen at the proximal end.
- the catheter has one aperture corresponding to each of the at least two lumens located at the distal end of the catheter.
- FIG. 1 is a top perspective view of the shunt and ventricular catheter according to the present invention
- FIG. 2 is a partial perspective view, with parts broken away, showing the interior of the ventricular catheter according to the present invention
- FIG. 3 is a cross-sectional view taken along lines 3 - 3 of FIG. 2 and looking in the direction of the arrows;
- FIG. 4 is a cross-sectional view taken along lines 4 - 4 of FIG. 3 and looking in the direction of the arrows;
- FIG. 4A is a cross-sectional view taken along lines 4 A- 4 A of FIG. 3 and looking in the direction of the arrows;
- FIG. 5 is a cross-sectional view taken along lines 5 - 5 of FIG. 3 and looking in the direction of the arrows;
- FIG. 6 is a partial top view of a prior art ventricular catheter
- FIG. 7 is cross-sectional view taken along lines 7 - 7 of FIG. 6 and looking in the direction of the arrows;
- FIG. 8A is a partial top view of the ventricular catheter according to the present invention.
- FIG. 8B is a partial top view of the ventricular catheter according to the present invention.
- FIGS. 1-5 , 8 A, 8 B and 9 a shunt 10 and a ventricular catheter 12 in accordance with the present invention is illustrated.
- shunt 10 has a housing 14 , which has an inlet 16 , an outlet 18 and a flow control mechanism disposed therein.
- Ventricular catheter 12 is connected to inlet 16 of the housing.
- Catheter 12 has a longitudinal length, a proximal end 20 , a distal end 22 , and an inner lumen 24 extending therethrough.
- Inner lumen 24 is a single lumen at proximal end 20 of the catheter and is comprised of two or more lumens 24 1 , 24 11 , 24 111 , 24 1111 , etc. at the distal end 22 of catheter 12 .
- Catheter 12 is preferably made of silicone.
- catheter 12 can be impregnated with antimicrobial antibiotics, such as the CODMAN® BACTISEAL® catheter, which is commercially sold by Codman & Shurtleff, Inc. of Raynham, Mass.
- Ventricular catheter 12 has only one aperture 26 at distal end 22 of catheter 12 corresponding to each of the lumens 24 1 , 24 111 , 24 1111 , etc. There are preferably between 2 and 7lumens, with only three and four lumens being shown in the drawing Figures for the sake of brevity. Of course, one skilled in the art would readily know how to make the ventricular catheter of the present invention with multiple lumens based on the present disclosure.
- Each tapering slit 30 receives cerebrospinal fluid (CSF) when in use.
- Each aperture 26 has an enlarged opening 28 at the distal end and transitions from the enlarged opening to a tapering slit 30 at the proximal end of the aperture.
- a portion 32 between the enlarged opening 28 and the tapering slit 30 is a slit 32 of constant thickness.
- a slit 42 of constant thickness can be disposed between the enlarged opening 28 and the proximal end of the aperture with no tapering slit being utilized.
- the entire aperture, from the enlarged opening 28 to the proximal end of tapering slit 30 is in fluid communication with its respective lumen 24 1 , 24 111 , 24 1111 , etc.
- the enlarged opening 28 of each aperture has a smooth concave inner surface 34 , similar to a spoon shape.
- multiple lumens 24 1 , 24 111 , 24 1111 , etc. in accordance with the present invention help prevent complete occlusion of ventricular catheter 12 .
- ventricular catheter 12 can only be completely occluded if all the lumens become blocked.
- any ingrowth of choroid plexus or ependymal tissue must extend beyond this junction to cause complete occlusion and interconnection of tissue from multiple apertures, which is unlikely to happen because of the length the tissue has to grow.
- the only other way that the choroid plexus or ependymal tissue would cause a complete occlusion is for the tissue to block each of the multiple lumens 24 beyond the slit 30 , or to occlude the entire slit 30 and the aperture 26 .
- the slit lumen geometry is preferably tapered or purposely shaped to provide resistance to fluid flow through the slit that corresponds to the size of the pathway provided by the slit.
- the size of the slit opening distributes the pressure gradient over a larger distance and surface area than conventional ventricular catheters. Diffusing the pressure gradient diminishes the attractive fluid forces and diminishes areas of high fluid flow, thereby lessens the propensity for tissue ingrowth.
- tissue ingrowth 36 is illustrated. As can be seen, tissue ingrowth into aperture 26 will not interconnect with tissue ingrowth from another lumen. Thus, should the ventricular catheter 12 need to be removed, catheter 12 will be pulled back out and tissue ingrowth 36 can be removed from the lumen at the wider end of the taper or at the enlarged opening 28 , as illustrated in FIG. 8B . In contrast, in the prior art, tissue ingrowth 36 can be rather difficult to remover from the ventricular catheter should the ventricular catheter 12 need to be removed, as discussed above.
- ventricular catheter 12 has a blunt distal end 38 to permit the catheter to be introduced into the brain without damaging brain tissue.
- an inner concave surface 40 is sized to receive a stylet for use in introducing the catheter.
Abstract
Description
- The present invention relates generally to a shunt and a catheter having a system for reducing the risk of blockage or obstruction of the catheter apertures and also increases the ease of revision surgery if the catheter is removed.
- Hydrocephalus is a neurological condition that is caused by the abnormal accumulation of cerebrospinal fluid (CSF) within the ventricles, or cavities, of the brain. CSF is a clear, colorless fluid that is primarily produced by the choroid plexus and surrounds the brain and spinal cord. CSF constantly circulates through the ventricular system of the brain and is ultimately absorbed into the bloodstream. CSF aids in the protection of the brain and spinal cord. Because CSF keeps the brain and spinal cord buoyant, it acts as a protective cushion or “shock absorber” to prevent injuries to the central nervous system.
- Hydrocephalus, which affects children and adults, arises when the normal drainage of CSF in the brain is blocked in some way. Such blockage can be caused by a number of factors, including, for example, genetic predisposition, intraventricular or intracranial hemorrhage, infections such as meningitis, head trauma, or the like. Blockage of the flow of CSF consequently creates an imbalance between the amount of CSF produced by the choroid plexus and the rate at which CSF is absorbed into the bloodstream, thereby increasing pressure on the brain, which causes the ventricles to enlarge.
- Hydrocephalus is most often treated by surgically inserting a shunt system that diverts the flow of CSF from the ventricle to another area of the body where the CSF can be absorbed as part of the circulatory system. Shunt systems come in a variety of models, and typically share similar functional components. These components include a ventricular catheter which is introduced through a burr hole in the skull and implanted in the patient's ventricle, a drainage catheter that carries the CSF to its ultimate drainage site, and optionally a flow-control mechanism, e.g., shunt valve, that regulates the one-way flow of CSF from the ventricle to the drainage site to maintain normal pressure within the ventricles. The ventricular catheter typically contains multiple holes or apertures positioned along the length of the ventricular catheter to allow the CSF to enter into the shunt system, as shown in
FIGS. 6 and 7 . - Shunting is considered one of the basic neurosurgical procedures, yet it has the highest complication rate. The most common complication with shunting is obstruction of the system. Although obstruction or clogging may occur at any point along the shunt system, it most frequently occurs at the ventricular end of the shunt system. While there are several ways that the ventricular catheter may become blocked or clogged, obstruction is typically caused by growth of tissue, such as the choroid plexus, around the catheter and into the apertures, as shown in
FIG. 7 . The apertures of the ventricular catheter can also be obstructed by debris, bacteria, or coagulated blood. - Some of these problems can be treated by backflushing, which is a process that uses the CSF present in the shunt system to remove the obstructing matter. This process can be ineffective, however, due to the small size of the apertures of the ventricular catheter and due to the small amount of flushing liquid available in the shunt system. Other shunt systems have been designed to include a mechanism for flushing the shunt system. For example, some shunt systems include a pumping device within the system which causes fluid in the system to flow with considerable pressure and velocity, thereby flushing the system. As with the process of backflushing, using a built-in mechanism to flush the shunt system can also fail to remove the obstruction due to factors such as the size of the apertures and the degree and extent to which the apertures have been clogged.
- Occluded ventricular catheters can also be repaired by cauterizing the catheter to remove blocking tissue, thereby reopening existing apertures that have become occluded. Alternatively, new apertures can be created in the catheter. These repairs, however, may be incapable of removing obstructions from the ventricular catheter depending on the location of the clogged apertures. Additionally, the extent of tissue growth into and around the catheter can also preclude the creation of additional apertures, for example, in situations where the tissue growth covers a substantial portion of the ventricular catheter. Another disadvantage of creating new apertures to repair an occluded ventricular catheter is that this method fails to prevent or reduce the risk of repeated obstructions.
- Because attempts at flushing or repairing a blocked ventricular catheter are often futile and ineffective, occlusion is more often treated by replacing the catheter. Although this can be accomplished by removing the obstructed catheter from the ventricle, the growth of the choroid plexus and other tissues around the catheter and into the apertures can hinder removal and replacement of the catheter. Care must be exercised to avoid damage to the choroid plexus, which can cause severe injury to the patient, such as, for example, hemorrhaging. Not only do these procedures pose a significant risk of injury to the patient, they can also be very costly, especially when shunt obstruction is a recurring problem.
- Accordingly, there exists a need for a shunt and a ventricular catheter that minimizes or eliminates the risk of blockage or obstruction of the catheter apertures, that increases the ease of revision surgery if the catheter is removed and reduces the need for repeated repair and/or replacement.
- The present invention provides a shunt that includes a housing having an inlet, an outlet and a flow control mechanism disposed within the housing. A ventricular catheter is connected to the inlet of the housing. The catheter has a longitudinal length, a proximal end, a distal end, and an inner lumen extending therethrough. The inner lumen of the catheter includes at least two lumens at the distal end and has only one lumen at the proximal end. The catheter has one aperture corresponding to each of the at least two lumens located at the distal end of the catheter.
-
FIG. 1 is a top perspective view of the shunt and ventricular catheter according to the present invention; -
FIG. 2 is a partial perspective view, with parts broken away, showing the interior of the ventricular catheter according to the present invention; -
FIG. 3 is a cross-sectional view taken along lines 3-3 ofFIG. 2 and looking in the direction of the arrows; -
FIG. 4 is a cross-sectional view taken along lines 4-4 ofFIG. 3 and looking in the direction of the arrows; -
FIG. 4A is a cross-sectional view taken along lines 4A-4A ofFIG. 3 and looking in the direction of the arrows; -
FIG. 5 is a cross-sectional view taken along lines 5-5 ofFIG. 3 and looking in the direction of the arrows; -
FIG. 6 is a partial top view of a prior art ventricular catheter; -
FIG. 7 is cross-sectional view taken along lines 7-7 ofFIG. 6 and looking in the direction of the arrows; -
FIG. 8A is a partial top view of the ventricular catheter according to the present invention; and -
FIG. 8B is a partial top view of the ventricular catheter according to the present invention. - Referring now to
FIGS. 1-5 , 8A, 8B and 9 a shunt 10 and aventricular catheter 12 in accordance with the present invention is illustrated. - As illustrated in
FIG. 1 , shunt 10 has a housing 14, which has an inlet 16, anoutlet 18 and a flow control mechanism disposed therein.Ventricular catheter 12 is connected to inlet 16 of the housing.Catheter 12 has a longitudinal length, aproximal end 20, adistal end 22, and aninner lumen 24 extending therethrough.Inner lumen 24 is a single lumen atproximal end 20 of the catheter and is comprised of two ormore lumens distal end 22 ofcatheter 12.Catheter 12 is preferably made of silicone. In addition,catheter 12 can be impregnated with antimicrobial antibiotics, such as the CODMAN® BACTISEAL® catheter, which is commercially sold by Codman & Shurtleff, Inc. of Raynham, Mass. -
Ventricular catheter 12 has only oneaperture 26 atdistal end 22 ofcatheter 12 corresponding to each of thelumens aperture 26 has anenlarged opening 28 at the distal end and transitions from the enlarged opening to a tapering slit 30 at the proximal end of the aperture. In some examples of the present invention, for eachaperture 26, aportion 32 between theenlarged opening 28 and the tapering slit 30 is aslit 32 of constant thickness. Likewise, in other examples of the present invention, for eachaperture 26, there may be noportion 32 between theenlarged opening 28 and the tapering slit 30. In addition, as illustrated inFIG. 9 , for eachaperture 26, aslit 42 of constant thickness can be disposed between theenlarged opening 28 and the proximal end of the aperture with no tapering slit being utilized. The entire aperture, from theenlarged opening 28 to the proximal end of taperingslit 30 is in fluid communication with itsrespective lumen enlarged opening 28 of each aperture has a smooth concaveinner surface 34, similar to a spoon shape. - The use of
multiple lumens ventricular catheter 12. In the present invention,ventricular catheter 12 can only be completely occluded if all the lumens become blocked. In addition, because the transition from multiple lumens to asingle lumen 24 occurs from about 0.5 to about 3.0 centimeters from the distal end of the ventricular catheter, any ingrowth of choroid plexus or ependymal tissue must extend beyond this junction to cause complete occlusion and interconnection of tissue from multiple apertures, which is unlikely to happen because of the length the tissue has to grow. The only other way that the choroid plexus or ependymal tissue would cause a complete occlusion is for the tissue to block each of themultiple lumens 24 beyond theslit 30, or to occlude theentire slit 30 and theaperture 26. - The slit lumen geometry is preferably tapered or purposely shaped to provide resistance to fluid flow through the slit that corresponds to the size of the pathway provided by the slit. The size of the slit opening distributes the pressure gradient over a larger distance and surface area than conventional ventricular catheters. Diffusing the pressure gradient diminishes the attractive fluid forces and diminishes areas of high fluid flow, thereby lessens the propensity for tissue ingrowth.
- Referring now to
FIGS. 8A and 8B of the present invention,tissue ingrowth 36 is illustrated. As can be seen, tissue ingrowth intoaperture 26 will not interconnect with tissue ingrowth from another lumen. Thus, should theventricular catheter 12 need to be removed,catheter 12 will be pulled back out andtissue ingrowth 36 can be removed from the lumen at the wider end of the taper or at theenlarged opening 28, as illustrated inFIG. 8B . In contrast, in the prior art,tissue ingrowth 36 can be rather difficult to remover from the ventricular catheter should theventricular catheter 12 need to be removed, as discussed above. - Referring now to
FIGS. 2 and 3 ,ventricular catheter 12, has a bluntdistal end 38 to permit the catheter to be introduced into the brain without damaging brain tissue. In addition, an innerconcave surface 40 is sized to receive a stylet for use in introducing the catheter. - It will be understood that the foregoing is only illustrative of the principles of the invention, and that various modifications can be made by those skilled in the art without departing from the scope and spirit of the invention. All references cited herein are expressly incorporated by reference in their entirety.
Claims (29)
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
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US12/894,111 US20120078159A1 (en) | 2010-09-29 | 2010-09-29 | Multi-lumen ventricular drainage catheter |
CA2749653A CA2749653C (en) | 2010-09-29 | 2011-08-19 | Multiple lumen ventricular drainage catheter |
CO11119195A CO6640044A1 (en) | 2010-09-29 | 2011-09-14 | Multilumen ventricular drainage catheter |
AU2011226839A AU2011226839A1 (en) | 2010-09-29 | 2011-09-23 | Multi-lumen ventricular drainage catheter |
JP2011212506A JP2012071135A (en) | 2010-09-29 | 2011-09-28 | Multi-lumen ventricular drainage catheter |
EP11183166.5A EP2436419B1 (en) | 2010-09-29 | 2011-09-28 | Multiple lumen ventricular drainage catheter |
US14/182,997 US10232151B2 (en) | 2010-09-29 | 2014-02-18 | Multi-lumen ventricular drainage catheter |
AU2016204328A AU2016204328B2 (en) | 2010-09-29 | 2016-06-24 | Multi-lumen ventricular drainage catheter |
Applications Claiming Priority (1)
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US12/894,111 US20120078159A1 (en) | 2010-09-29 | 2010-09-29 | Multi-lumen ventricular drainage catheter |
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US14/182,997 Continuation US10232151B2 (en) | 2010-09-29 | 2014-02-18 | Multi-lumen ventricular drainage catheter |
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US20120078159A1 true US20120078159A1 (en) | 2012-03-29 |
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US12/894,111 Abandoned US20120078159A1 (en) | 2010-09-29 | 2010-09-29 | Multi-lumen ventricular drainage catheter |
US14/182,997 Active 2033-05-21 US10232151B2 (en) | 2010-09-29 | 2014-02-18 | Multi-lumen ventricular drainage catheter |
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US14/182,997 Active 2033-05-21 US10232151B2 (en) | 2010-09-29 | 2014-02-18 | Multi-lumen ventricular drainage catheter |
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US (2) | US20120078159A1 (en) |
EP (1) | EP2436419B1 (en) |
JP (1) | JP2012071135A (en) |
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CO (1) | CO6640044A1 (en) |
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US8852156B2 (en) | 2012-02-08 | 2014-10-07 | Windrose Medical, Llc. | Device for implanting medical catheters |
US20160331927A1 (en) * | 2014-01-31 | 2016-11-17 | The Regents Of The University Of Colorado, A Body Corporate | Ventricular Catheter |
WO2019035020A1 (en) | 2017-08-18 | 2019-02-21 | Aljazaeri Ayman Hassan A | Drainage catheter with retractable internal drains |
US10493249B2 (en) | 2014-04-18 | 2019-12-03 | Anuncia, Inc. | System and methods for shunting fluid |
US10518069B2 (en) | 2016-10-28 | 2019-12-31 | Integra LifeSciences Switzerland Sarl | Implantable valve assembly with extended lifespan |
US10639461B2 (en) | 2013-01-22 | 2020-05-05 | Anuncia, Inc. | Systems and methods for shunting fluid |
US10765847B1 (en) | 2019-12-10 | 2020-09-08 | Ayman H. Al-Jazaeri | Single lumen drainage catheter with extendable and retractable drains |
US10792480B2 (en) | 2016-10-13 | 2020-10-06 | Anuncia, Inc. | Shunt flushers and related methods |
WO2023089344A1 (en) * | 2021-11-22 | 2023-05-25 | Buckingham Medical Technologies Ltd. | Medical cannulas |
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CA2904628C (en) | 2013-03-15 | 2024-02-13 | Children's Medical Center Corporation | Shunt flusher |
CA2987931A1 (en) * | 2015-06-01 | 2016-12-08 | University Of Massachusetts | Catheter assemblies |
US20210338991A1 (en) * | 2020-04-29 | 2021-11-04 | Medtronic Xomed, Inc. | System and Method for a Covering |
WO2022237108A1 (en) * | 2021-05-08 | 2022-11-17 | 宁波市第一医院 | Anti-blocking nephrostomy tube and curved drainage nephrostomy tube |
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US8852156B2 (en) | 2012-02-08 | 2014-10-07 | Windrose Medical, Llc. | Device for implanting medical catheters |
US10639461B2 (en) | 2013-01-22 | 2020-05-05 | Anuncia, Inc. | Systems and methods for shunting fluid |
US20210016068A1 (en) * | 2013-01-22 | 2021-01-21 | Anuncia, Inc. | Systems and methods for shunting fluid |
US20160331927A1 (en) * | 2014-01-31 | 2016-11-17 | The Regents Of The University Of Colorado, A Body Corporate | Ventricular Catheter |
US10493249B2 (en) | 2014-04-18 | 2019-12-03 | Anuncia, Inc. | System and methods for shunting fluid |
US10792480B2 (en) | 2016-10-13 | 2020-10-06 | Anuncia, Inc. | Shunt flushers and related methods |
US10518069B2 (en) | 2016-10-28 | 2019-12-31 | Integra LifeSciences Switzerland Sarl | Implantable valve assembly with extended lifespan |
WO2019035020A1 (en) | 2017-08-18 | 2019-02-21 | Aljazaeri Ayman Hassan A | Drainage catheter with retractable internal drains |
US10500331B2 (en) | 2017-08-18 | 2019-12-10 | Ayman H. Al-Jazaeri | Drainage catheter with retractable internal drains |
US10765847B1 (en) | 2019-12-10 | 2020-09-08 | Ayman H. Al-Jazaeri | Single lumen drainage catheter with extendable and retractable drains |
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Also Published As
Publication number | Publication date |
---|---|
AU2016204328A1 (en) | 2016-07-14 |
AU2011226839A1 (en) | 2012-04-12 |
CA2749653C (en) | 2019-12-10 |
CA2749653A1 (en) | 2012-03-29 |
US10232151B2 (en) | 2019-03-19 |
AU2016204328B2 (en) | 2018-05-24 |
EP2436419B1 (en) | 2019-05-08 |
CO6640044A1 (en) | 2013-03-22 |
US20140228734A1 (en) | 2014-08-14 |
JP2012071135A (en) | 2012-04-12 |
EP2436419A1 (en) | 2012-04-04 |
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