US20100331619A1 - Endoscopic heart surgery method - Google Patents

Endoscopic heart surgery method Download PDF

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Publication number
US20100331619A1
US20100331619A1 US12/871,172 US87117210A US2010331619A1 US 20100331619 A1 US20100331619 A1 US 20100331619A1 US 87117210 A US87117210 A US 87117210A US 2010331619 A1 US2010331619 A1 US 2010331619A1
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United States
Prior art keywords
heart
inserted portion
endoscopic
surgery method
endoscope
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12/871,172
Inventor
Shunichiro MIYOSHI
Michihiro Sugahara
Masayuki Kobayashi
Yoshiro Okazaki
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Olympus Corp
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Olympus Corp
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Filing date
Publication date
Priority claimed from JP2009285073A external-priority patent/JP5415925B2/en
Priority to US12/757,210 priority Critical patent/US8747297B2/en
Application filed by Olympus Corp filed Critical Olympus Corp
Priority to US12/871,172 priority patent/US20100331619A1/en
Assigned to OLYMPUS CORPORATION reassignment OLYMPUS CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: KOBAYASHI, MASAYUKI, OKAZAKI, YOSHIRO, SUGAHARA, MICHIHIRO
Publication of US20100331619A1 publication Critical patent/US20100331619A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/05Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064Constructional details of the endoscope body
    • A61B1/00071Insertion part of the endoscope body
    • A61B1/0008Insertion part of the endoscope body characterised by distal tip features
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064Constructional details of the endoscope body
    • A61B1/00071Insertion part of the endoscope body
    • A61B1/0008Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00082Balloons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • A61B1/00174Optical arrangements characterised by the viewing angles
    • A61B1/00177Optical arrangements characterised by the viewing angles for 90 degrees side-viewing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00238Type of minimally invasive operation
    • A61B2017/00243Type of minimally invasive operation cardiac
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37Surgical systems with images on a monitor during operation
    • A61B2090/376Surgical systems with images on a monitor during operation using X-rays, e.g. fluoroscopy

Definitions

  • the present invention relates to an endoscopic heart surgery method.
  • an endoscope is inserted into the space between the heart and the pericardium surrounding the heart (pericardial space), and the heart is treated while observing a treated area of the heart with the endoscope without cutting the chest open.
  • U.S. Patent Application Publication No. 2004/0064138 discloses a surgery method in which an endoscope and a surgical instrument are inserted into the pericardial space from separate holes formed by puncturing the pericardium, and the atrial appendage is removed while observing the operation of the surgical instrument with the endoscope. In such surgery, the endoscope is inserted into the pericardial space and the heart is observed and treated while still pulsing.
  • the present invention has been made in view of the situation described above, and it is an object thereof to provide an endoscopic heart surgery method with which it is possible to observe an endoscopic image with a stable field of view in the pericardial space.
  • the present invention employs the following solution.
  • the present invention provides an endoscopic heart surgery method including an inserting step of inserting an inserted portion of an endoscope into a body from the subxiphoid area and inserting the inserted portion into the pericardial space by penetrating the pericardium in the vicinity of the heart apex; a moving step of advancing the inserted portion toward the base of the heart so that the inserted portion passes through the vicinity of the roof of the pericardial space and is moved toward the heart apex to a treated area in the pericardial space; and an observing step of observing the treated area with the endoscope.
  • FIG. 1 is an illustration showing a state where an inserted portion is inserted into the pericardial space in an inserting step.
  • FIGS. 2A and 2B are illustrations for explaining a method of performing a posture changing step by tilting the bed, in which FIG. 2A shows a case where the posture of the patient is changed in the left-right direction and FIG. 2B shows a case where the posture of the patient is changed in the top-bottom direction.
  • FIG. 3 is an illustration for explaining a method of performing a posture changing step by changing the position of the patient on the bed.
  • FIG. 4 is an illustration for explaining the positional relationship between the pericardium and the heart and the positional relationship between the heart and an endoscope when the posture of the patient is changed in the posture changing step before the inserting step so that the head side becomes lower.
  • FIG. 5 is an illustration showing a state where the inserted portion is disposed in an I-shaped configuration in a moving step.
  • FIG. 6 is an illustration showing a state where the inserted portion is disposed in an inverted U-shaped configuration in the moving step.
  • FIG. 7 is an illustration for explaining movement of the inserted portion during rotation of the inserted portion in a rotating step.
  • FIG. 8 is an illustration showing an example of the relationship between the moving position of the endoscope and the posture of the patient in the posture changing step performed concurrently with the moving step.
  • FIG. 9 is an illustration for explaining the positional relationship between the pericardium and the heart and the positional relationship between the heart and the endoscope when the patient lies in the prone position or the semi-prone position.
  • FIG. 10 is an illustration showing a state where pulsation is suppressed by a device projected from a channel in a pulsation suppressing step.
  • FIG. 11 is an illustration showing a state where pulsation is suppressed by a device inserted into the pericardial space from a hole different from that used for an endoscope in the pulsation suppressing step.
  • FIGS. 12A to 12E show radiographic images, acquired according to a certain procedure, of the inserted portion inserted into the pericardial space in an endoscopic heart surgery method according to the present invention, in which FIG. 12A shows a state where the inserted portion is disposed in an I-shaped configuration, FIG. 12B shows a state where the bending portion is bent in the vicinity of the roof of the pericardial space, FIG. 12C shows a state where the inserted portion is rotated clockwise, and FIGS. 12D and 12E show states where the inserted portion is advanced further and disposed in an inverted U-shaped configuration.
  • FIG. 14 is a schematic illustration showing the placement of the inserted portion and the relationship between the viewing direction and field of view of the endoscope in the case of a inverted U-shaped configuration.
  • FIGS. 1 to 13 used as reference, show examples where a front-viewing endoscope is used as an endoscope.
  • an endoscope having an outer diameter dimension less than or equal to 6 mm is used.
  • an endoscope having a CCD camera installed at the distal end thereof is used.
  • the endoscopic heart surgery method includes an inserting step of inserting an inserted portion 1 of the endoscope from the subxiphoid area C into the pericardial space A, a moving step of advancing the inserted portion 1 in the pericardial space A to a treated area via the vicinity of the roof of the pericardial space A, an observation-space ensuring step of ensuring an observation space in the pericardial space A, a posture changing step of changing the posture of the patient, a pulsation suppressing step of suppressing the pulsation of the heart B within the field of view of the endoscope, and an observing step of observing the treated area.
  • the posture changing step is performed before another step or concurrently with another step.
  • the inserted portion 1 is inserted into the body via a sheath S from a hole D formed by puncturing the subxiphoid area C, and the pericardium E is penetrated in the vicinity of the heart apex.
  • the sheath S is omitted.
  • the pericardium E is penetrated with the inserted portion 1 by using the Seldinger method. That is, before inserting the inserted portion 1 through the hole at the subxiphoid area C, a puncture needle having a thin diameter is inserted from the subxiphoid area C, the pericardium E is punctured with the distal end thereof, and the puncture needle is inserted to a mid position in the pericardial space A. Then, a guide wire is inserted into the pericardial space A via a lumen formed inside the puncture needle. Then, with the guide wire remaining in the pericardial space A, the puncture needle is removed from the body.
  • the sheath S is inserted into the pericardial space A along the guide wire, and then the guide wire is removed from the body. Then, the inserted portion 1 is inserted into the pericardial space A through the inside of the sheath S.
  • the serdinger method as described above, it is possible to readily introduce the inserted portion 1 into the pericardial space A from a punctured region F formed at a desired position of the pericardium E.
  • the posture changing step may be performed before the inserting step.
  • the posture changing step is performed by tilting the bed H with the body of the patient G immobilized on the bed H with a belt I or the like.
  • the posture changing step is performed by changing the position of the patient G on the fixed bed H and maintaining the posture of the patient G stable with a belt I or a cushion J.
  • the inserted portion 1 inserted into the pericardial space A is advanced toward the base of the heart along the anterior right ventricular wall.
  • the inserted portion 1 is disposed in an I-shaped configuration following the surface of the heart B.
  • the inserted portion 1 is advanced toward the heart apex through the vicinity of the roof of the pericardial space A. Accordingly, as shown in FIG. 6 , the inserted portion 1 is disposed in an inverted U-shaped configuration, so that the heart B is observed from the base of the heart towards the heart apex.
  • the inserted portion 1 is abutted against the inner surface of the pericardium E by its own restoring force in an outward radial direction, by which the inserted portion 1 tends to restore its substantially linear shape.
  • the inserted portion 1 is strongly supported by the entire pericardium E.
  • a bending step is performed. That is, the inserted portion 1 is passed through the vicinity of the roof while bending a bending portion 2 at a maximum angle. At this time, since the bending portion 2 is bent with the pericardium E acting as a fulcrum, the distal end of the inserted portion 1 is disposed at a position away from the surface of the heart B. Thus, an appropriate observation distance is ensured between the distal end of the inserted portion 1 and the surface of the heart B, so that it is possible to observe a sharp endoscopic image of the surface of the heart B.
  • a rotating step is performed simultaneously with the bending step; that is, the inserted portion 1 is advanced and passed through the vicinity of the roof while rotating the inserted portion 1 in a circumferential direction.
  • the distal end of the inserted portion 1 is rotated with the roof of the pericardium E acting as a fulcrum and is moved towards the left and right sides of the heart B.
  • the rotating direction of the inserted portion 1 and adjusting the amount of rotation and the amount of insertion of the inserted portion and the bending angle of the bending portion 2 it is possible to readily move the distal end of the inserted portion to any part of the heart B.
  • the inserted portion 1 by rotating the inserted portion 1 clockwise, it is possible to steer the distal end of the inserted portion 1 to the right atrium, the right ventricle, the right coronary artery, the right coronary vein, the right atrial appendage, the heart apex, or the anterior interventricular groove.
  • the inserted portion 1 by rotating the inserted portion 1 counterclockwise, it is possible to steer the distal end of the inserted portion 1 to the left atrium, the left ventricle, the left coronary artery, the left coronary vein, the coronary sinus, the left atrial appendage, the heart apex, or the posterior interventricular groove.
  • the patient lies in a lateral position.
  • the liquid is injected into the pericardial space A together with a gas.
  • a gas for example, 10 to 20 ml of physiological saline and 50 to 100 ml of gas are injected into the pericardial space A. Accordingly, it is possible to observe the position of the liquid surface clearly.
  • the posture changing step is performed concurrently with the moving step.
  • the posture of the patient G is changed in accordance with movement of the inserted portion 1 so that the distal end of the inserted portion 1 is constantly disposed above the heart B.
  • the bed H may be tilted with the body of the patient G immobilized on the bed H, or the position of the patient G on the bed H may be changed from the supine position to the lateral position, semi-lateral position, prone position, or semi-prone position.
  • the endoscope is moved following the side wall of the left ventricle, the patient G lies in the right lateral position, as shown in FIG. 8 .
  • a wide pericardial space A is ensured between the side wall of the left ventricle and the pericardium E.
  • a space ensuring step After disposing the distal end of the inserted portion 1 at the treated area in the moving step, a space ensuring step, a posture changing step and a pulsation suppressing step are performed.
  • the space ensuring step is performed by injecting a fluid into the pericardial space A via a channel. Accordingly, the pericardium E is pushed and expanded outward, whereby the pericardial space A can be expanded.
  • a fluid for example, a gas, such as carbon dioxide, is used.
  • the amount of the fluid injected is less than or equal to 150 ml.
  • the posture of the patient G is changed so that the observed area of the heart B faces upward.
  • the patient G is placed in the right lateral position.
  • the patient G is placed in the right semi-lateral position, and the bed H is tilted so that the leg side becomes higher.
  • the patient G is placed in the prone position or the semi-prone position.
  • the patient G is placed in the right lateral position or the right semi-lateral position.
  • the base of the posterior wall the patient G is placed in the prone position or the semi-prone position.
  • the bed H having a hole K at the position of the chest of the patient G is used, and the endoscope is operated from under the patient G.
  • the posture changing step is performed as described above, since the fluid injected into the pericardial space A in the space ensuring step is lighter than the heart B, the fluid moves upward in the pericardial space A. That is, in the vicinity of the observed area of the heart B, the fluid pushes and expands the pericardium E, so that it is possible to ensure a wider observation space.
  • the posture changing step since it has been difficult to perform observation by inserting an endoscope into the back side of the heart in the conventional posture for operation, in which the patient lies horizontally in the prone position, the posture changing step here is particularly effective when observing the back side of the heart.
  • the pulsation suppressing step is performed by abutting against the surface of the heart B a device 3 inserted into the pericardial space A via a channel, as shown in FIG. 10 .
  • a device 3 a tube, basket forceps, a balloon, or the like is used.
  • the pulsation suppressing step is performed by inserting the device 3 into the pericardial space A from another punctured region F′ formed at the pericardium E and abutting the device 3 against the surface of the heart B, as shown in FIG. 11 . Accordingly, it is possible to partially suppress the pulsation of the heart B, thereby reducing movement of the treated area in the endoscopic image.
  • the treated area is observed in the endoscopic image.
  • the treated area may be treated by introducing an instrument into the pericardial space A via another channel that is different from the channel through which the device for suppressing pulsation is inserted.
  • the treated area may be treated by inserting an instrument into the pericardial space A from another punctured region formed at the pericardium E.
  • FIGS. 12A to 12E show radiographic images (fluoroscopic images) acquired by actually applying the endoscopic heart surgery method according to the present invention to the heart B of a pig.
  • FIG. 12A shows a state where the inserted portion 1 is disposed in an I-shaped configuration. At this time, it is possible to observe the left atrial appendage and the root of the aorta.
  • FIG. 12B shows a state where the distal end of the inserted portion 1 is trapped at the roof of the pericardial space A between the right ventricular outflow and the left atrial appendage.
  • FIG. 12C shows a state where the bending portion 2 is bent maximally and the inserted portion 1 is advanced while rotating the inserted portion 1 clockwise.
  • FIGS. 12D and 12E show states where the inserted portion 1 is advanced further and disposed in an inverted U-shaped configuration.
  • the inserted portion 1 by disposing the inserted portion 1 in an inverted U-shaped configuration in the pericardial space A, the inserted portion 1 is stably supported by the pericardium E.
  • the distal end of the inserted portion 1 is prevented from rotating or moving in an unintended direction on the surface of the heart B. Accordingly, it is possible to stably retain the distal end of the inserted portion 1 at a desired position and posture and to observe an endoscopic image with a stable position of the field of view.
  • the inserted portion 1 is advanced so as to slide over the surface of the heart B, and the distal end of the inserted portion 1 is oriented ahead toward the pericardium E.
  • the pericardium E occupies a large portion of the endoscopic image, and the heart B appears in only a part of the endoscopic image.
  • the surface of the heart B serves as a fulcrum of bending of the bending portion 2 , and the distal end of the inserted portion 1 becomes separated from the surface of the heart B.
  • the pericardium E is displayed in the entire field of view of the endoscopic image.
  • a lateral-viewing endoscope or an oblique-viewing endoscope may be used as the endoscope.
  • a lateral-viewing or oblique-viewing endoscope it is possible to readily increase the ratio of the surface of the heart B displayed in the endoscopic image, as shown in FIG. 14 .
  • an oblique-viewing endoscope with a viewing direction of 30° to 60° is suitable. Accordingly, it is possible to show both the surface of the heart B and the pericardium E at an appropriate ratio in the endoscopic image.
  • the present invention has the following aspects.
  • the present invention provides an endoscopic heart surgery method including an inserting step of inserting an inserted portion of an endoscope into a body from the subxiphoid area and inserting the inserted portion into the pericardial space by penetrating the pericardium in the vicinity of the heart apex; a moving step of advancing the inserted portion toward the base of the heart so that the inserted portion passes through the vicinity of the roof of the pericardial space and is moved toward the heart apex to a treated area in the pericardial space; and an observing step of observing the treated area with the endoscope.
  • the inserted portion inserted into the pericardial space from the vicinity of the heart apex in the inserting step is moved to the treated area via the roof of the pericardial space in the moving step, whereby the inserted portion is disposed in an inverted U-shaped configuration following the shape of the inner surface of the pericardium, so that a mid position of the inserted portion is strongly supported by the entire pericardium. Accordingly, even with the heart pulsing, it is possible to observe a desired region stably in the pericardial space with the inserted portion in a stable position and posture.
  • the moving step may include a rotating step of passing the inserted portion through the vicinity of the roof of the pericardial space while rotating the inserted portion in a circumferential direction thereof.
  • the moving step may include a bending step of passing the inserted portion through the vicinity of the roof of the pericardial space while bending a bending portion provided at the inserted portion.
  • the inserted portion in the rotating step, may be rotated clockwise, and in the observing step, the right atrium, the right ventricle, the right coronary artery, the right coronary vein, the right atrial appendage, the heart apex, or the anterior interventricular groove may be observed.
  • the inserted portion in the rotating step, may be rotated counterclockwise, and in the observing step, the left atrium, the left ventricle, the left coronary artery, the left coronary vein, the coronary sinus, the left atrial appendage, the heart apex, or the posterior interventricular groove may be observed.
  • the inserting step and the moving step may be performed under radiography.
  • the pericardium is penetrated with the inserted portion by the Seldinger method.
  • a space ensuring step of ensuring a space between the pericardium and the surface of the heart prior to the observing step by injecting a fluid into the pericardial space via a channel in the inserted portion.
  • the heart becomes deviated to the lower side in the pericardial space due to gravity, whereby the pericardial space above the heart expands, so that it is possible to ensure an even wider observation space.
  • the fluid injected in the pericardial space in the space ensuring step moves upward, so that the pericardium is pushed and expanded above the heart.
  • an orientation confirming step of confirming the orientation of the inserted portion by observing an organ that is outside and adjacent to the pericardium transparently through the pericardium.
  • an orientation confirming step of confirming the orientation of the inserted portion by injecting a liquid into the pericardial space and observing the position of the surface of the liquid.
  • a pulsation suppressing step of suppressing the pulsation of the heart prior to the observing step by projecting a device toward the heart from a channel in the inserted portion and abutting the device against the heart.
  • a pulsation suppressing step of suppressing the pulsation of the heart prior to the observing step by abutting against the heart a device that is inserted into the pericardial space by penetrating the pericardium at a position different from that of the endoscope.
  • an oblique-viewing endoscope or a lateral-viewing endoscope may be used as the endoscope.
  • an endoscope having a viewing angle wider than or equal to 120° is used as the endoscope.

Abstract

It is an object to provide an endoscopic heart surgery method with which it is possible to observe an endoscopic image with a stable field of view in the pericardial space. Provided is an endoscopic heart surgery method including an inserting step of inserting an inserted portion of an endoscope into a body from the subxiphoid area and inserting the inserted portion into the pericardial space by penetrating the pericardium in the vicinity of the heart apex; a moving step of advancing the inserted portion toward the base of the heart so that the inserted portion passes through the vicinity of the roof of the pericardial space and is moved toward the heart apex to a treated area in the pericardial space; and an observing step of observing the treated area with the endoscope.

Description

    CROSS REFERENCE TO RELATED APPLICATIONS
  • This application claims the benefit of U.S. Provisional Application No. 61/244,586, filed Sep. 22, 2009, which is hereby incorporated by reference herein in its entirety.
  • This application is a continuation-in-part of U.S. patent application Ser. No. 12/757,210, filed Apr. 9, 2010, and U.S. patent application Ser. No. 12/714,827, filed Mar. 1, 2010, which are hereby incorporated by reference herein in their entireties.
  • This application claims the benefit of Japanese Patent Application No. 2009-048460 and Japanese Patent Application No. 2009-285073, the contents of which are incorporated herein by reference.
  • BACKGROUND OF THE INVENTION
  • 1. Field of the Invention
  • The present invention relates to an endoscopic heart surgery method.
  • 2. Description of Related Art
  • In conventional known heart surgery methods, an endoscope is inserted into the space between the heart and the pericardium surrounding the heart (pericardial space), and the heart is treated while observing a treated area of the heart with the endoscope without cutting the chest open. For example, U.S. Patent Application Publication No. 2004/0064138 discloses a surgery method in which an endoscope and a surgical instrument are inserted into the pericardial space from separate holes formed by puncturing the pericardium, and the atrial appendage is removed while observing the operation of the surgical instrument with the endoscope. In such surgery, the endoscope is inserted into the pericardial space and the heart is observed and treated while still pulsing.
  • BRIEF SUMMARY OF THE INVENTION
  • The present invention has been made in view of the situation described above, and it is an object thereof to provide an endoscopic heart surgery method with which it is possible to observe an endoscopic image with a stable field of view in the pericardial space.
  • In order to achieve the above object, the present invention employs the following solution.
  • The present invention provides an endoscopic heart surgery method including an inserting step of inserting an inserted portion of an endoscope into a body from the subxiphoid area and inserting the inserted portion into the pericardial space by penetrating the pericardium in the vicinity of the heart apex; a moving step of advancing the inserted portion toward the base of the heart so that the inserted portion passes through the vicinity of the roof of the pericardial space and is moved toward the heart apex to a treated area in the pericardial space; and an observing step of observing the treated area with the endoscope.
  • BRIEF DESCRIPTION OF THE SEVERAL VIEWS OF THE DRAWINGS
  • FIG. 1 is an illustration showing a state where an inserted portion is inserted into the pericardial space in an inserting step.
  • FIGS. 2A and 2B are illustrations for explaining a method of performing a posture changing step by tilting the bed, in which FIG. 2A shows a case where the posture of the patient is changed in the left-right direction and FIG. 2B shows a case where the posture of the patient is changed in the top-bottom direction.
  • FIG. 3 is an illustration for explaining a method of performing a posture changing step by changing the position of the patient on the bed.
  • FIG. 4 is an illustration for explaining the positional relationship between the pericardium and the heart and the positional relationship between the heart and an endoscope when the posture of the patient is changed in the posture changing step before the inserting step so that the head side becomes lower.
  • FIG. 5 is an illustration showing a state where the inserted portion is disposed in an I-shaped configuration in a moving step.
  • FIG. 6 is an illustration showing a state where the inserted portion is disposed in an inverted U-shaped configuration in the moving step.
  • FIG. 7 is an illustration for explaining movement of the inserted portion during rotation of the inserted portion in a rotating step.
  • FIG. 8 is an illustration showing an example of the relationship between the moving position of the endoscope and the posture of the patient in the posture changing step performed concurrently with the moving step.
  • FIG. 9 is an illustration for explaining the positional relationship between the pericardium and the heart and the positional relationship between the heart and the endoscope when the patient lies in the prone position or the semi-prone position.
  • FIG. 10 is an illustration showing a state where pulsation is suppressed by a device projected from a channel in a pulsation suppressing step.
  • FIG. 11 is an illustration showing a state where pulsation is suppressed by a device inserted into the pericardial space from a hole different from that used for an endoscope in the pulsation suppressing step.
  • FIGS. 12A to 12E show radiographic images, acquired according to a certain procedure, of the inserted portion inserted into the pericardial space in an endoscopic heart surgery method according to the present invention, in which FIG. 12A shows a state where the inserted portion is disposed in an I-shaped configuration, FIG. 12B shows a state where the bending portion is bent in the vicinity of the roof of the pericardial space, FIG. 12C shows a state where the inserted portion is rotated clockwise, and FIGS. 12D and 12E show states where the inserted portion is advanced further and disposed in an inverted U-shaped configuration.
  • FIG. 13 is a schematic illustration showing the placement of the inserted portion and the field of view in the case of the I-shaped configuration.
  • FIG. 14 is a schematic illustration showing the placement of the inserted portion and the relationship between the viewing direction and field of view of the endoscope in the case of a inverted U-shaped configuration.
  • DETAILED DESCRIPTION OF THE INVENTION
  • An endoscopic heart surgery method according to an embodiment of the present invention will be described below with reference to the drawings.
  • FIGS. 1 to 13, used as reference, show examples where a front-viewing endoscope is used as an endoscope. In an endoscopic heart surgery according to this embodiment, from the viewpoints of maneuverability in the pericardial space A and the influence on the heart B, preferably, an endoscope having an outer diameter dimension less than or equal to 6 mm is used. Furthermore, in order to acquire a sharp image, preferably, an endoscope having a CCD camera installed at the distal end thereof is used.
  • The endoscopic heart surgery method according to this embodiment includes an inserting step of inserting an inserted portion 1 of the endoscope from the subxiphoid area C into the pericardial space A, a moving step of advancing the inserted portion 1 in the pericardial space A to a treated area via the vicinity of the roof of the pericardial space A, an observation-space ensuring step of ensuring an observation space in the pericardial space A, a posture changing step of changing the posture of the patient, a pulsation suppressing step of suppressing the pulsation of the heart B within the field of view of the endoscope, and an observing step of observing the treated area. The posture changing step is performed before another step or concurrently with another step.
  • First, in the inserting step, while observing the position of the inserted portion 1 inside the body in a radiographic image, as shown in FIG. 1, the inserted portion 1 is inserted into the body via a sheath S from a hole D formed by puncturing the subxiphoid area C, and the pericardium E is penetrated in the vicinity of the heart apex. In FIG. 2 and the subsequent figures, the sheath S is omitted.
  • At this time, preferably, the pericardium E is penetrated with the inserted portion 1 by using the Seldinger method. That is, before inserting the inserted portion 1 through the hole at the subxiphoid area C, a puncture needle having a thin diameter is inserted from the subxiphoid area C, the pericardium E is punctured with the distal end thereof, and the puncture needle is inserted to a mid position in the pericardial space A. Then, a guide wire is inserted into the pericardial space A via a lumen formed inside the puncture needle. Then, with the guide wire remaining in the pericardial space A, the puncture needle is removed from the body. Then, the sheath S is inserted into the pericardial space A along the guide wire, and then the guide wire is removed from the body. Then, the inserted portion 1 is inserted into the pericardial space A through the inside of the sheath S. By using the serdinger method as described above, it is possible to readily introduce the inserted portion 1 into the pericardial space A from a punctured region F formed at a desired position of the pericardium E.
  • The posture changing step may be performed before the inserting step.
  • As shown in FIGS. 2A and 2B, the posture changing step is performed by tilting the bed H with the body of the patient G immobilized on the bed H with a belt I or the like. Alternatively, as shown in FIG. 3, the posture changing step is performed by changing the position of the patient G on the fixed bed H and maintaining the posture of the patient G stable with a belt I or a cushion J.
  • In the case of the ordinary position for operation, in which the patient lies horizontally in the supine position, there is almost no gap between the pericardium E and the heart B in the vicinity of the heart apex. Here, as shown in FIG. 4, in the posture changing step, the bed H with the body of the patient G immobilized on the bed H is tilted so that the head side of the patient G becomes lower. Thus, the heart B becomes deviated to the head side inside the pericardium E, whereby the pericardial space A on the heart apex side expands. Accordingly, it is possible to introduce the inserted portion 1 into the pericardial space A more easily in the inserting step. After the inserting step, the posture of the patient G may be returned to the horizontal position.
  • Then, in the moving step, the inserted portion 1 inserted into the pericardial space A is advanced toward the base of the heart along the anterior right ventricular wall. At this time, as shown in FIG. 5, the inserted portion 1 is disposed in an I-shaped configuration following the surface of the heart B. Then, the inserted portion 1 is advanced toward the heart apex through the vicinity of the roof of the pericardial space A. Accordingly, as shown in FIG. 6, the inserted portion 1 is disposed in an inverted U-shaped configuration, so that the heart B is observed from the base of the heart towards the heart apex. In the inverted U-shaped configuration, the inserted portion 1 is abutted against the inner surface of the pericardium E by its own restoring force in an outward radial direction, by which the inserted portion 1 tends to restore its substantially linear shape. As a result, the inserted portion 1 is strongly supported by the entire pericardium E.
  • Here, a bending step is performed. That is, the inserted portion 1 is passed through the vicinity of the roof while bending a bending portion 2 at a maximum angle. At this time, since the bending portion 2 is bent with the pericardium E acting as a fulcrum, the distal end of the inserted portion 1 is disposed at a position away from the surface of the heart B. Thus, an appropriate observation distance is ensured between the distal end of the inserted portion 1 and the surface of the heart B, so that it is possible to observe a sharp endoscopic image of the surface of the heart B.
  • Furthermore, a rotating step is performed simultaneously with the bending step; that is, the inserted portion 1 is advanced and passed through the vicinity of the roof while rotating the inserted portion 1 in a circumferential direction. At this time, as shown in FIG. 7, the distal end of the inserted portion 1 is rotated with the roof of the pericardium E acting as a fulcrum and is moved towards the left and right sides of the heart B. Here, by choosing the rotating direction of the inserted portion 1 and adjusting the amount of rotation and the amount of insertion of the inserted portion and the bending angle of the bending portion 2, it is possible to readily move the distal end of the inserted portion to any part of the heart B. Specifically, by rotating the inserted portion 1 clockwise, it is possible to steer the distal end of the inserted portion 1 to the right atrium, the right ventricle, the right coronary artery, the right coronary vein, the right atrial appendage, the heart apex, or the anterior interventricular groove. On the other hand, by rotating the inserted portion 1 counterclockwise, it is possible to steer the distal end of the inserted portion 1 to the left atrium, the left ventricle, the left coronary artery, the left coronary vein, the coronary sinus, the left atrial appendage, the heart apex, or the posterior interventricular groove. In the case of observing the posterior left ventricular wall, preferably, the patient lies in a lateral position.
  • During the moving step, the orientation of the distal end of the inserted portion 1 may be confirmed by performing an orientation confirming step as needed. The orientation confirming step is performed by observing an organ adjacent to the pericardium E, for example, the lungs or the thoracic diaphragm, transparently through the pericardium E. By using these organs as landmarks, it is possible to ascertain the direction of the field of view. Alternatively, the orientation confirming step is performed by injecting a liquid into the pericardial space A via a channel formed through the inserted portion 1 and observing the position of the surface of the liquid. As the liquid, for example, physiological saline is used. Accordingly, it is possible to ascertain the vertically upward and downward directions. Preferably, the liquid is injected into the pericardial space A together with a gas. For example, 10 to 20 ml of physiological saline and 50 to 100 ml of gas are injected into the pericardial space A. Accordingly, it is possible to observe the position of the liquid surface clearly.
  • The posture changing step is performed concurrently with the moving step. Here, the posture of the patient G is changed in accordance with movement of the inserted portion 1 so that the distal end of the inserted portion 1 is constantly disposed above the heart B. As the method of changing the posture of the patient G, as described above, the bed H may be tilted with the body of the patient G immobilized on the bed H, or the position of the patient G on the bed H may be changed from the supine position to the lateral position, semi-lateral position, prone position, or semi-prone position. For example, when the endoscope is moved following the side wall of the left ventricle, the patient G lies in the right lateral position, as shown in FIG. 8. Thus, a wide pericardial space A is ensured between the side wall of the left ventricle and the pericardium E. By changing the posture of the patient G so that the pericardial space A is dilated at the position of the distal end of the inserted portion 1 as described above, it is possible to move the inserted portion 1 smoothly in the pericardial space A without rubbing the heart B or the pericardium E with the inserted portion 1.
  • After disposing the distal end of the inserted portion 1 at the treated area in the moving step, a space ensuring step, a posture changing step and a pulsation suppressing step are performed.
  • The space ensuring step is performed by injecting a fluid into the pericardial space A via a channel. Accordingly, the pericardium E is pushed and expanded outward, whereby the pericardial space A can be expanded. As the fluid, for example, a gas, such as carbon dioxide, is used. Preferably, the amount of the fluid injected is less than or equal to 150 ml. By expanding the pericardial space A in this manner, it is possible to ensure a distance between the distal end of the inserted portion 1 and the surface of the heart B and to observe a sharp image of the surface of the heart B.
  • In the posture changing step here, the posture of the patient G is changed so that the observed area of the heart B faces upward. Specifically, when observing the anterior side wall or the base of the anterior wall, the patient G is placed in the right lateral position. When observing the anterior wall, the patient G is placed in the right semi-lateral position, and the bed H is tilted so that the leg side becomes higher. When observing the lower posterior wall or the posterior wall, the patient G is placed in the prone position or the semi-prone position. When observing the posterior side wall, the patient G is placed in the right lateral position or the right semi-lateral position. When observing the base of the posterior wall, the patient G is placed in the prone position or the semi-prone position. When observing the heart B with the patient G placed in the prone position or the semi-prone position, as shown in FIG. 9, the bed H having a hole K at the position of the chest of the patient G is used, and the endoscope is operated from under the patient G.
  • When the posture changing step is performed as described above, since the fluid injected into the pericardial space A in the space ensuring step is lighter than the heart B, the fluid moves upward in the pericardial space A. That is, in the vicinity of the observed area of the heart B, the fluid pushes and expands the pericardium E, so that it is possible to ensure a wider observation space. In particular, since it has been difficult to perform observation by inserting an endoscope into the back side of the heart in the conventional posture for operation, in which the patient lies horizontally in the prone position, the posture changing step here is particularly effective when observing the back side of the heart.
  • The pulsation suppressing step is performed by abutting against the surface of the heart B a device 3 inserted into the pericardial space A via a channel, as shown in FIG. 10. As the device 3, a tube, basket forceps, a balloon, or the like is used. Alternatively, the pulsation suppressing step is performed by inserting the device 3 into the pericardial space A from another punctured region F′ formed at the pericardium E and abutting the device 3 against the surface of the heart B, as shown in FIG. 11. Accordingly, it is possible to partially suppress the pulsation of the heart B, thereby reducing movement of the treated area in the endoscopic image.
  • Then, in the observing step, the treated area is observed in the endoscopic image. In this step, the treated area may be treated by introducing an instrument into the pericardial space A via another channel that is different from the channel through which the device for suppressing pulsation is inserted. Alternatively, the treated area may be treated by inserting an instrument into the pericardial space A from another punctured region formed at the pericardium E.
  • FIGS. 12A to 12E show radiographic images (fluoroscopic images) acquired by actually applying the endoscopic heart surgery method according to the present invention to the heart B of a pig. FIG. 12A shows a state where the inserted portion 1 is disposed in an I-shaped configuration. At this time, it is possible to observe the left atrial appendage and the root of the aorta. FIG. 12B shows a state where the distal end of the inserted portion 1 is trapped at the roof of the pericardial space A between the right ventricular outflow and the left atrial appendage. FIG. 12C shows a state where the bending portion 2 is bent maximally and the inserted portion 1 is advanced while rotating the inserted portion 1 clockwise. FIGS. 12D and 12E show states where the inserted portion 1 is advanced further and disposed in an inverted U-shaped configuration.
  • As described above, according to this embodiment, by disposing the inserted portion 1 in an inverted U-shaped configuration in the pericardial space A, the inserted portion 1 is stably supported by the pericardium E. Thus, even when the heart B is pulsing, the distal end of the inserted portion 1 is prevented from rotating or moving in an unintended direction on the surface of the heart B. Accordingly, it is possible to stably retain the distal end of the inserted portion 1 at a desired position and posture and to observe an endoscopic image with a stable position of the field of view.
  • Furthermore, in the case of the I-shaped configuration, as shown in FIGS. 5 and 13, the inserted portion 1 is advanced so as to slide over the surface of the heart B, and the distal end of the inserted portion 1 is oriented ahead toward the pericardium E. In this state, it is difficult to ensure an adequate distance between the distal end of the inserted portion 1 and the surface of the heart B. Thus, even if it is attempted to observe the surface of the heart B, the surface of the heart B is too close to the objective lens, so that focusing is not possible. Furthermore, the pericardium E occupies a large portion of the endoscopic image, and the heart B appears in only a part of the endoscopic image. If the bending portion 2 is bent, on the other hand, the surface of the heart B serves as a fulcrum of bending of the bending portion 2, and the distal end of the inserted portion 1 becomes separated from the surface of the heart B. Thus, the pericardium E is displayed in the entire field of view of the endoscopic image.
  • On the other hand, in the case of the inverted U-shaped configuration, as shown in FIG. 14, an adequate distance is ensured between the distal end of the inserted portion 1 and the surface of the heart B. Accordingly, it is possible to capture a sharp image of the surface of the heart B. Furthermore, by bending the bending portion 2 in this shape, it is possible to capture an image of the surface of the heart B from an angle viewing from above, thereby showing the heart B in a wider range of the endoscopic image. Furthermore, by using an endoscope with a wider viewing angle, preferably, a viewing angle wider than or equal to 120°, it is possible to observe the surface of the heart B even more readily.
  • Furthermore, when an attempt is made to mechanically widen the gap between the heart B and the pericardium E, a burden is imposed on the heart B, the pericardium E, or the neighboring tissue. In contrast, with the posture changing step in this embodiment, it is possible to readily ensure a space at a desired position of the pericardial space A without imposing an excessive burden on the heart B or other tissue.
  • In the embodiment described above, a lateral-viewing endoscope or an oblique-viewing endoscope may be used as the endoscope. By using a lateral-viewing or oblique-viewing endoscope, it is possible to readily increase the ratio of the surface of the heart B displayed in the endoscopic image, as shown in FIG. 14. As the endoscope used for an endoscopic heart surgery according to the present invention, an oblique-viewing endoscope with a viewing direction of 30° to 60° is suitable. Accordingly, it is possible to show both the surface of the heart B and the pericardium E at an appropriate ratio in the endoscopic image. In the case where a lateral-viewing endoscope is used, even though the objective lens is disposed closer to the surface of the heart B, by shaping the inserted portion 1 into an inverted U-shaped configuration, it is possible to keep the objective lens at a position away from the surface of the heart B.
  • The present invention has the following aspects.
  • The present invention provides an endoscopic heart surgery method including an inserting step of inserting an inserted portion of an endoscope into a body from the subxiphoid area and inserting the inserted portion into the pericardial space by penetrating the pericardium in the vicinity of the heart apex; a moving step of advancing the inserted portion toward the base of the heart so that the inserted portion passes through the vicinity of the roof of the pericardial space and is moved toward the heart apex to a treated area in the pericardial space; and an observing step of observing the treated area with the endoscope.
  • According to the present invention, the inserted portion inserted into the pericardial space from the vicinity of the heart apex in the inserting step is moved to the treated area via the roof of the pericardial space in the moving step, whereby the inserted portion is disposed in an inverted U-shaped configuration following the shape of the inner surface of the pericardium, so that a mid position of the inserted portion is strongly supported by the entire pericardium. Accordingly, even with the heart pulsing, it is possible to observe a desired region stably in the pericardial space with the inserted portion in a stable position and posture.
  • In the above invention, the moving step may include a rotating step of passing the inserted portion through the vicinity of the roof of the pericardial space while rotating the inserted portion in a circumferential direction thereof.
  • Accordingly, it is possible to advance the distal end of the inserted portion toward the heart apex while maneuvering it in the left and right directions of the heart with the roof of the pericardial space acting as a fulcrum.
  • In the above invention, the moving step may include a bending step of passing the inserted portion through the vicinity of the roof of the pericardial space while bending a bending portion provided at the inserted portion.
  • Accordingly, since the bending portion is bent with the pericardium acting as a fulcrum, an adequate observation distance is ensured between the surface of the heart and the distal end of the inserted portion. Thus, it is possible to observe an endoscopic image with proper focusing at the surface of the heart.
  • In the above invention, in the rotating step, the inserted portion may be rotated clockwise, and in the observing step, the right atrium, the right ventricle, the right coronary artery, the right coronary vein, the right atrial appendage, the heart apex, or the anterior interventricular groove may be observed. Alternatively, in the above invention, in the rotating step, the inserted portion may be rotated counterclockwise, and in the observing step, the left atrium, the left ventricle, the left coronary artery, the left coronary vein, the coronary sinus, the left atrial appendage, the heart apex, or the posterior interventricular groove may be observed.
  • As described above, by just choosing the rotating direction of the inserted portion, it is possible to readily make the distal end of the inserted portion approach a desired region of the heart.
  • In the above invention, the inserting step and the moving step may be performed under radiography.
  • Accordingly, it is possible to readily operate the endoscope while confirming the position thereof.
  • In the above invention, preferably, in the inserting step, the pericardium is penetrated with the inserted portion by the Seldinger method.
  • Accordingly, the degree of invasiveness in the pericardium is reduced.
  • In the above invention, there may be included a space ensuring step of ensuring a space between the pericardium and the surface of the heart prior to the observing step by injecting a fluid into the pericardial space via a channel in the inserted portion.
  • Accordingly, it is possible to further facilitate treatment of the treated area with an instrument.
  • Alternatively, in the above-described invention, there may be further provided a posture changing step of changing the posture of the patient before the observing step so that the distal end of the inserted portion is disposed above the heart in the pericardial space.
  • Accordingly, the heart becomes deviated to the lower side in the pericardial space due to gravity, whereby the pericardial space above the heart expands, so that it is possible to ensure an even wider observation space.
  • Alternatively, in the above-described invention, there may be further provided a posture changing step of changing the posture of the patient after the space ensuring step so that the distal end of the inserted portion is disposed above the heart in the pericardial space.
  • Accordingly, the fluid injected in the pericardial space in the space ensuring step moves upward, so that the pericardium is pushed and expanded above the heart. Thus, it is possible to ensure an even wider observation space in the observation step performed next.
  • In the above invention, there may be included an orientation confirming step of confirming the orientation of the inserted portion by observing an organ that is outside and adjacent to the pericardium transparently through the pericardium.
  • Accordingly, it is possible to readily confirm the orientation of the inserted portion.
  • Alternatively, in the above invention, there may be included an orientation confirming step of confirming the orientation of the inserted portion by injecting a liquid into the pericardial space and observing the position of the surface of the liquid.
  • Accordingly, since the liquid accumulates downward due to its own weight, it is possible to readily confirm the vertically upward and downward directions from the position of the liquid surface.
  • In the above invention, there may be included a pulsation suppressing step of suppressing the pulsation of the heart prior to the observing step by projecting a device toward the heart from a channel in the inserted portion and abutting the device against the heart.
  • Alternatively, in the above invention, there may be provided a pulsation suppressing step of suppressing the pulsation of the heart prior to the observing step by abutting against the heart a device that is inserted into the pericardial space by penetrating the pericardium at a position different from that of the endoscope.
  • Accordingly, it is possible to acquire an endoscopic image with an even more stable field of view.
  • In the above invention, an oblique-viewing endoscope or a lateral-viewing endoscope may be used as the endoscope.
  • Accordingly, it is possible to readily observe the surface of the heart even when the bending portion is not bent.
  • In the above invention, preferably, an endoscope having a viewing angle wider than or equal to 120° is used as the endoscope.
  • Accordingly, it is possible to show a wider area of the heart in the endoscopic image.
  • In the above invention, preferably, an endoscope with an outer diameter less than or equal to 6 mm is used as the endoscope.
  • Accordingly, it is possible to alleviate the stress placed on the heart.

Claims (19)

1. An endoscopic heart surgery method comprising:
an inserting step of inserting an inserted portion of an endoscope into a body from the subxiphoid area and inserting the inserted portion into the pericardial space by penetrating the pericardium in the vicinity of the heart apex;
a moving step of advancing the inserted portion toward the base of the heart so that the inserted portion passes through the vicinity of the roof of the pericardial space and is moved toward the heart apex to a treated area in the pericardial space; and
an observing step of observing the treated area with the endoscope.
2. An endoscopic heart surgery method according to claim 1, wherein the moving step includes a rotating step of passing the inserted portion through the vicinity of the roof of the pericardial space while rotating the inserted portion in a circumferential direction thereof.
3. An endoscopic heart surgery method according to claim 1, wherein the moving step includes a bending step of passing the inserted portion through the vicinity of the roof of the pericardial space while bending a bending portion provided at the inserted portion.
4. An endoscopic heart surgery method according to claim 2, wherein
in the rotating step, the inserted portion is rotated clockwise, and
in the observing step, the right atrium, the right ventricle, the right coronary artery, the right coronary vein, the right atrial appendage, the heart apex, or the anterior interventricular groove is observed.
5. An endoscopic heart surgery method according to claim 2, wherein
in the rotating step, the inserted portion is rotated counterclockwise, and
in the observing step, the left atrium, the left ventricle, the left coronary artery, the left coronary vein, the coronary sinus, the left atrial appendage, the heart apex, or the posterior interventricular groove is observed.
6. An endoscopic heart surgery method according to claim 1, wherein the inserting step and the moving step are performed under radiography.
7. An endoscopic heart surgery method according to claim 1, wherein, in the inserting step, the pericardium is penetrated with the inserted portion by the Seldinger method.
8. An endoscopic heart surgery method according to claim 1, further comprising a space ensuring step of ensuring a space between the pericardium and the surface of the heart prior to the observing step by injecting a fluid into the pericardial space via a channel in the inserted portion.
9. An endoscopic heart surgery method according to claim 1, further comprising a posture changing step of changing the posture of the patient before the observing step so that the distal end of the inserted portion is disposed above the heart in the pericardial space.
10. An endoscopic heart surgery method according to claim 9, wherein the posture changing step is performed before the inserting step.
11. An endoscopic heart surgery method according to claim 9, wherein the posture changing step is performed concurrently with the moving step.
12. An endoscopic heart surgery method according to claim 8, further comprising a posture changing step of changing the posture of the patient after the space ensuring step so that the distal end of the inserted portion is disposed above the heart in the pericardial space.
13. An endoscopic heart surgery method according to claim 1, further comprising an orientation confirming step of confirming the orientation of the inserted portion by observing an organ that is outside and adjacent to the pericardium transparently through the pericardium.
14. An endoscopic heart surgery method according to claim 1, further comprising an orientation confirming step of confirming the orientation of the inserted portion by injecting a liquid into the pericardial space and observing the position of the surface of the liquid.
15. An endoscopic heart surgery method according to claim 1, further comprising a pulsation suppressing step of suppressing the pulsation of the heart prior to the observing step by projecting a device toward the heart from a channel of the inserted portion and abutting the device against the heart.
16. An endoscopic heart surgery method according to claim 1, further comprising a pulsation suppressing step of suppressing the pulsation of the heart prior to the observing step by abutting against the heart a device that is inserted into the pericardial space by penetrating the pericardium at a position different from that of the endoscope.
17. An endoscopic heart surgery method according to claim 1, wherein an oblique-viewing endoscope or a lateral-viewing endoscope is used as the endoscope.
18. An endoscopic heart surgery method according to claim 1, wherein an endoscope having a viewing angle wider than or equal to 120° is used as the endoscope.
19. An endoscopic heart surgery method according to claim 1, wherein an endoscope with an outer diameter less than or equal to 6 mm is used as the endoscope.
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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9393001B2 (en) 2011-07-29 2016-07-19 Olympus Corporation Operation method of endoscope
US10159586B2 (en) 2015-06-29 2018-12-25 480 Biomedical Inc. Scaffold loading and delivery systems
US10201639B2 (en) 2017-05-01 2019-02-12 480 Biomedical, Inc. Drug-eluting medical implants
US10232082B2 (en) 2015-06-29 2019-03-19 480 Biomedical, Inc. Implantable scaffolds for treatment of sinusitis
US10278812B2 (en) 2015-06-29 2019-05-07 480 Biomedical, Inc. Implantable scaffolds and methods for treatment of sinusitis
US10973664B2 (en) 2015-12-30 2021-04-13 Lyra Therapeutics, Inc. Scaffold loading and delivery systems
US11172807B2 (en) 2016-05-23 2021-11-16 Olympus Corporation Endoscope device and endoscope system with deforming insertion portion wire
US20220054118A1 (en) * 2020-08-20 2022-02-24 Satoshi AWADU Flexible endoscope insertion method for examining the lateral wall of the lumen or the lateral side of the organ
US11304686B2 (en) 2011-06-17 2022-04-19 Koninklijke Philips N.V. System and method for guided injection during endoscopic surgery

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5718077B2 (en) * 2011-02-03 2015-05-13 オリンパス株式会社 Endoscope
EP3603501A1 (en) 2012-08-09 2020-02-05 University of Iowa Research Foundation Catheter systems for surrounding a tissue structure
JP6104045B2 (en) * 2013-05-16 2017-03-29 オリンパス株式会社 Medical device guide for heart
WO2015103574A1 (en) 2014-01-06 2015-07-09 Iowa Approach Inc. Apparatus and methods for renal denervation ablation
EP4238521A3 (en) 2014-05-07 2023-11-29 Farapulse, Inc. Methods and apparatus for selective tissue ablation
WO2015192027A1 (en) 2014-06-12 2015-12-17 Iowa Approach Inc. Method and apparatus for rapid and selective transurethral tissue ablation
WO2015192018A1 (en) 2014-06-12 2015-12-17 Iowa Approach Inc. Method and apparatus for rapid and selective tissue ablation with cooling
EP3206613B1 (en) 2014-10-14 2019-07-03 Farapulse, Inc. Apparatus for rapid and safe pulmonary vein cardiac ablation
US10660702B2 (en) 2016-01-05 2020-05-26 Farapulse, Inc. Systems, devices, and methods for focal ablation
US20170189097A1 (en) 2016-01-05 2017-07-06 Iowa Approach Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US10172673B2 (en) 2016-01-05 2019-01-08 Farapulse, Inc. Systems devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
US10130423B1 (en) 2017-07-06 2018-11-20 Farapulse, Inc. Systems, devices, and methods for focal ablation
WO2017218734A1 (en) 2016-06-16 2017-12-21 Iowa Approach, Inc. Systems, apparatuses, and methods for guide wire delivery
US10617867B2 (en) 2017-04-28 2020-04-14 Farapulse, Inc. Systems, devices, and methods for delivery of pulsed electric field ablative energy to esophageal tissue
EP3681391A1 (en) 2017-09-12 2020-07-22 Farapulse, Inc. Systems, apparatuses, and methods for ventricular focal ablation
EP3459469A1 (en) 2017-09-23 2019-03-27 Universität Zürich Medical occluder device
US10750936B2 (en) * 2017-11-02 2020-08-25 Olympus Corporation Pericardial-cavity observing method
JP2021522903A (en) 2018-05-07 2021-09-02 ファラパルス,インコーポレイテッド Systems, devices, and methods for delivering ablation energy to tissues
WO2019217317A1 (en) 2018-05-07 2019-11-14 Farapulse, Inc. Systems, apparatuses, and methods for filtering high voltage noise induced by pulsed electric field ablation
CN116327352A (en) 2018-05-07 2023-06-27 波士顿科学医学有限公司 Epicardial ablation catheter
JP2022501112A (en) 2018-09-20 2022-01-06 ファラパルス,インコーポレイテッド Systems, devices, and methods for the delivery of pulsed field ablation energy to endocardial tissue
US10625080B1 (en) 2019-09-17 2020-04-21 Farapulse, Inc. Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation
JP2022549717A (en) 2019-09-26 2022-11-28 ウニベルシタット チューリッヒ left atrial appendage closure device
US11065047B2 (en) 2019-11-20 2021-07-20 Farapulse, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US11497541B2 (en) 2019-11-20 2022-11-15 Boston Scientific Scimed, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US10842572B1 (en) 2019-11-25 2020-11-24 Farapulse, Inc. Methods, systems, and apparatuses for tracking ablation devices and generating lesion lines

Citations (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3281141A (en) * 1963-01-15 1966-10-25 American Sterilizer Co Surgical table
US4884567A (en) * 1987-12-03 1989-12-05 Dimed Inc. Method for transvenous implantation of objects into the pericardial space of patients
US5035231A (en) * 1987-04-27 1991-07-30 Olympus Optical Co., Ltd. Endoscope apparatus
US5309896A (en) * 1991-05-29 1994-05-10 Origin Medsystems, Inc. Retraction methods using endoscopic inflatable retraction devices
US5336252A (en) * 1992-06-22 1994-08-09 Cohen Donald M System and method for implanting cardiac electrical leads
US5549569A (en) * 1994-02-15 1996-08-27 Lawrence A. Lynn Ex vivo blood isolation system
US5697916A (en) * 1995-11-21 1997-12-16 Stat Medical Devices Inc. Hypodermic dosage measuring device
US5725525A (en) * 1993-03-16 1998-03-10 Ep Technologies, Inc. Multiple electrode support structures with integral hub and spline elements
US5759150A (en) * 1995-07-07 1998-06-02 Olympus Optical Co., Ltd. System for evulsing subcutaneous tissue
US5968017A (en) * 1997-10-14 1999-10-19 Merit Medical Systems, Inc. Pulse fluid infusion systems
US6071295A (en) * 1997-02-27 2000-06-06 Medivas Opcab, Inc. Device to hold an anastomotic site of coronary artery motionless and bloodless for the bypass operation
US6203490B1 (en) * 1998-05-28 2001-03-20 KRAJíĈEK MILAN Myocardial stabilizer
US20070023334A1 (en) * 2003-09-23 2007-02-01 Gambro Lundia Ab Apparatus, a system and a method relating to hemodialysis, hemodiafiltration, hemofiltration or peritoneal dialysis
US20070255100A1 (en) * 2006-01-06 2007-11-01 Olympus Medical Systems Corporation Medical method and medical system conducted percutaneous or using naturally occurring body orifice
US20080167621A1 (en) * 2005-05-16 2008-07-10 Wagner Gary S Multi-Barrel Syringe Having Integral Manifold
US7398781B1 (en) * 1999-08-10 2008-07-15 Maquet Cardiovascular, Llc Method for subxiphoid endoscopic access
US20080275371A1 (en) * 2003-09-04 2008-11-06 Ahof Biophysical Systems Inc. Vibrator with a plurality of contact nodes for treatment of myocardial ischemia
US7485624B2 (en) * 1999-08-10 2009-02-03 Allergan, Inc. Method for treating cardiac muscle disorders
US7621867B2 (en) * 2004-05-14 2009-11-24 Olympus Corporation Insertion device
US20100191164A1 (en) * 2007-06-29 2010-07-29 Futoshi Sasaki Hemodialysis apparatus
US7914444B2 (en) * 2003-12-15 2011-03-29 Olympus Corporation Endoscope system and endoscope

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3859985A (en) * 1973-06-27 1975-01-14 Becton Dickinson Co Angiography valve
US4063553A (en) * 1976-04-08 1977-12-20 Bell & Howell Company Pressure transducing methods and apparatus
US4224929A (en) * 1977-11-08 1980-09-30 Olympus Optical Co., Ltd. Endoscope with expansible cuff member and operation section
US4319568A (en) * 1979-10-29 1982-03-16 Vickers Limited Liquid dispensing apparatus
GB8424101D0 (en) * 1984-09-24 1984-10-31 Vi Tal Hospital Products Ltd Air-in-line detector
JPS6235318A (en) 1985-08-09 1987-02-16 Canon Inc Endoscope operating method
JP2575395B2 (en) 1987-07-15 1997-01-22 オリンパス光学工業株式会社 Antenna device for NMR measurement
JPH0255960A (en) 1988-08-20 1990-02-26 Fujikura Ltd Photoelectric current sensor
US4991603A (en) * 1989-10-30 1991-02-12 Siemens-Pacesetter, Inc. Transvenously placed defibrillation leads via an inferior vena cava access site and method of use
US5048537A (en) * 1990-05-15 1991-09-17 Medex, Inc. Method and apparatus for sampling blood
US5361752A (en) 1991-05-29 1994-11-08 Origin Medsystems, Inc. Retraction apparatus and methods for endoscopic surgery
US5795325A (en) * 1991-07-16 1998-08-18 Heartport, Inc. Methods and apparatus for anchoring an occluding member
AU3136993A (en) 1991-11-19 1993-06-15 Origin Medsystems, Inc. Endoscopic inflatable retraction devices for separating layers of tissue, and methods of using
US5297536A (en) * 1992-08-25 1994-03-29 Wilk Peter J Method for use in intra-abdominal surgery
US5324266A (en) * 1992-12-23 1994-06-28 Abbott Laboratories In-line sampling system incorporating an improved blood sampling device
US5400773A (en) * 1993-01-19 1995-03-28 Loma Linda University Medical Center Inflatable endoscopic retractor
US6478029B1 (en) * 1993-02-22 2002-11-12 Hearport, Inc. Devices and methods for port-access multivessel coronary artery bypass surgery
SE9303253D0 (en) 1993-10-05 1993-10-05 Siemens Elema Ab Instruments for peephole surgery
JPH08117232A (en) 1994-10-24 1996-05-14 Olympus Optical Co Ltd Biopsy needle
JPH08280815A (en) 1995-04-19 1996-10-29 Sumitomo Bakelite Co Ltd Catheter for stent delivery
JP3053566B2 (en) 1995-07-07 2000-06-19 オリンパス光学工業株式会社 Cavity securing tool
US5894843A (en) * 1996-02-20 1999-04-20 Cardiothoracic Systems, Inc. Surgical method for stabilizing the beating heart during coronary artery bypass graft surgery
CA2197614C (en) * 1996-02-20 2002-07-02 Charles S. Taylor Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft surgery
ES2128936B1 (en) 1996-05-22 2000-01-16 Patentes Novedades Sa PROCEDURE FOR OBTAINING PENTAERITRITOL.
US6059750A (en) * 1996-08-01 2000-05-09 Thomas J. Fogarty Minimally invasive direct cardiac massage device and method
JP3017451B2 (en) 1996-11-11 2000-03-06 オリンパス光学工業株式会社 Hood for endoscope
US5735791A (en) * 1997-01-31 1998-04-07 Research Medical, Inc. Inflatable heart elevation apparatus and method
US6390976B1 (en) * 1997-09-17 2002-05-21 Origin Medsystems, Inc. System to permit offpump beating heart coronary bypass surgery
US6015382A (en) * 1997-10-16 2000-01-18 General Surgical Innovations, Inc. Inflatable manipulator for organ positioning during surgery and method of use
US6017332A (en) * 1997-10-20 2000-01-25 Urrutia; Hector Medical dye delivery system
US6267717B1 (en) * 1998-03-31 2001-07-31 Advanced Research & Technology Institute Apparatus and method for treating a body structure with radiation
JPH11276422A (en) 1998-03-31 1999-10-12 Fuji Photo Optical Co Ltd Ultrasonic endoscope
US6740082B2 (en) * 1998-12-29 2004-05-25 John H. Shadduck Surgical instruments for treating gastro-esophageal reflux
US6309374B1 (en) 1998-08-03 2001-10-30 Insite Vision Incorporated Injection apparatus and method of using same
JP2000176011A (en) 1998-12-18 2000-06-27 Urrutia Hector Medical pigment transmitting system
DE60031970T2 (en) 1999-04-16 2007-06-14 Medivas, LLC, La Jolla DEVICE FOR STABILIZING A TREATMENT AGENCY
US7526342B2 (en) * 1999-08-10 2009-04-28 Maquet Cardiovascular Llc Apparatus for endoscopic cardiac mapping and lead placement
US6517477B1 (en) * 2000-01-27 2003-02-11 Scimed Life Systems, Inc. Catheter introducer system for exploration of body cavities
WO2001078809A1 (en) 2000-04-12 2001-10-25 Sherwood Services Ag Thoracentesis device with hyper-sensitive detection mechanism
US6471644B1 (en) * 2000-04-27 2002-10-29 Medtronic, Inc. Endoscopic stabilization device and method of use
JP4517321B2 (en) 2000-06-05 2010-08-04 有限会社エスアールジェイ Overtube
JP2002017854A (en) 2000-07-11 2002-01-22 Daiken Iki Kk Flow rate adjuster for medical liquid injector
US6666861B1 (en) * 2000-10-05 2003-12-23 James R. Grabek Atrial appendage remodeling device and method
US6786898B2 (en) * 2003-01-15 2004-09-07 Medtronic, Inc. Methods and tools for accessing an anatomic space
US6890295B2 (en) * 2002-10-31 2005-05-10 Medtronic, Inc. Anatomical space access tools and methods
US6706013B1 (en) * 2001-06-29 2004-03-16 Advanced Cardiovascular Systems, Inc. Variable length drug delivery catheter
JP4768154B2 (en) * 2001-06-29 2011-09-07 テルモ株式会社 Medical energy irradiation device
WO2003039354A1 (en) * 2001-10-18 2003-05-15 Atropos Limited A device to aid advancement of a colonoscope
JP3859491B2 (en) 2001-11-15 2006-12-20 オリンパス株式会社 Endoscope sheath
US7376456B2 (en) 2002-08-05 2008-05-20 Infraredx, Inc. Near-infrared spectroscopic analysis of blood vessel walls
JP4334838B2 (en) 2002-09-06 2009-09-30 オリンパス株式会社 Endoscope device
JP4088918B2 (en) 2002-09-13 2008-05-21 東レ・メディカル株式会社 Hemodialysis machine
JP4642477B2 (en) * 2003-01-21 2011-03-02 ティーエイチディー エス.ピー.エー. Surgical retractor for hemorrhoid artery
US7394976B2 (en) * 2003-03-25 2008-07-01 Arizant Healthcare Inc. Fluid warming cassette and system capable of operation under negative pressure
JP4274073B2 (en) * 2003-08-08 2009-06-03 住友ベークライト株式会社 Coronary artery bypass surgery instrument
US7341558B2 (en) * 2003-09-19 2008-03-11 Medcanica, Llc Pericardial retractor
US20050159645A1 (en) * 2003-11-12 2005-07-21 Bertolero Arthur A. Balloon catheter sheath
US7399272B2 (en) * 2004-03-24 2008-07-15 Medtronic, Inc. Methods and apparatus providing suction-assisted tissue engagement
US8926635B2 (en) * 2004-06-18 2015-01-06 Medtronic, Inc. Methods and devices for occlusion of an atrial appendage
US7229408B2 (en) * 2004-06-30 2007-06-12 Ethicon, Inc. Low profile surgical retractor
ITBO20040443A1 (en) * 2004-07-16 2004-10-16 Cefla Coop ORAL CABLE RETRACTOR
WO2006058434A1 (en) 2004-12-02 2006-06-08 Strauss Bradley H Augmentation of intraluminal microvessel formation to facilitate guide wire crossing in chronic total occlusions
US20080015569A1 (en) * 2005-02-02 2008-01-17 Voyage Medical, Inc. Methods and apparatus for treatment of atrial fibrillation
JP2006271831A (en) 2005-03-30 2006-10-12 Terumo Corp Medical treatment device and its usage
US20060259017A1 (en) * 2005-04-27 2006-11-16 Cardiac Pacemakers, Inc. Adhesive elements and methods for accessing the pericardial space
US20070088203A1 (en) * 2005-05-25 2007-04-19 Liming Lau Surgical assemblies and methods for visualizing and performing surgical procedures in reduced-access surgical sites
US7837688B2 (en) * 2005-06-13 2010-11-23 Globus Medical Spinous process spacer
JP2007029556A (en) * 2005-07-28 2007-02-08 Olympus Corp Insertion assisting appliance for medical apparatus
JP2007054333A (en) 2005-08-25 2007-03-08 Pentax Corp Oct probe, and oct system
US20070135686A1 (en) * 2005-12-14 2007-06-14 Pruitt John C Jr Tools and methods for epicardial access
EP1968466A2 (en) * 2005-12-19 2008-09-17 M. S. Abdou Devices for inter-vertebral orthopedic device placement
JP5116985B2 (en) * 2006-04-13 2013-01-09 富士フイルム株式会社 Endoscope
US8342183B2 (en) * 2006-04-19 2013-01-01 Vibrynt, Inc. Devices and methods for treatment of obesity
CN104887171B (en) * 2006-05-18 2018-03-20 智能医疗系统有限公司 Flexible endoscope system and its function
US20070270882A1 (en) * 2006-05-19 2007-11-22 Acorn Cardiovascular, Inc. Pericardium management method for intra-pericardial surgical procedures
US8092470B2 (en) * 2006-06-08 2012-01-10 Olympus Medical Systems Corp. Calculus crushing apparatus and medical procedure using endoscope
WO2008111070A2 (en) * 2007-03-12 2008-09-18 David Tolkowsky Devices and methods for performing medical procedures in tree-like luminal structures
JP2008259701A (en) * 2007-04-12 2008-10-30 Olympus Corp Apparatus inserted into living body
FR2914840A1 (en) 2007-04-16 2008-10-17 Lk2 Soc Responsabilite Limitee Connection for blood sampling device, has sampling valve sampling fluid sample contained in sampling path, where path has Luer lock type syringe that drives part of fluid contained in sampling path towards catheter path
EP2148608A4 (en) 2007-04-27 2010-04-28 Voyage Medical Inc Complex shape steerable tissue visualization and manipulation catheter
JP2008284108A (en) 2007-05-16 2008-11-27 Olympus Corp Stabilizer
WO2008142685A2 (en) * 2007-05-21 2008-11-27 Smart Medical Systems Ltd. Catheter including a bendable portion
JP5011024B2 (en) * 2007-08-10 2012-08-29 オリンパスメディカルシステムズ株式会社 Endoscope
US8311620B2 (en) * 2007-08-22 2012-11-13 Cardiac Pacemakers, Inc. Methods and apparatus to treat and prevent atrial tachyarrhythmias
JP2011510786A (en) * 2008-02-05 2011-04-07 シーヴィ デヴァイシズ,エルエルシー Steering engagement catheter apparatus, system and method
WO2009132009A1 (en) * 2008-04-21 2009-10-29 Medtronic, Inc. Suction force ablation device
US8690762B2 (en) * 2008-06-18 2014-04-08 Raytheon Company Transparent endoscope head defining a focal length
JP5745413B2 (en) * 2008-10-10 2015-07-08 サージクェスト,インコーポレーテッド Low profile surgical access device with anchor mechanism
EP2378990B1 (en) * 2008-12-22 2018-05-16 Synthes GmbH Expandable interspinous process spacer
US20100268029A1 (en) * 2009-04-21 2010-10-21 Xlumena, Inc. Methods and apparatus for advancing a device from one body lumen to another
US20100317925A1 (en) * 2009-06-12 2010-12-16 Banchieri Michael J Suction-assisted tissue stabilizers
WO2011041638A2 (en) * 2009-10-02 2011-04-07 Cardiofocus, Inc. Cardiac ablation system with automatic safety shut-off feature

Patent Citations (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3281141A (en) * 1963-01-15 1966-10-25 American Sterilizer Co Surgical table
US5035231A (en) * 1987-04-27 1991-07-30 Olympus Optical Co., Ltd. Endoscope apparatus
US4884567A (en) * 1987-12-03 1989-12-05 Dimed Inc. Method for transvenous implantation of objects into the pericardial space of patients
US5309896A (en) * 1991-05-29 1994-05-10 Origin Medsystems, Inc. Retraction methods using endoscopic inflatable retraction devices
US5336252A (en) * 1992-06-22 1994-08-09 Cohen Donald M System and method for implanting cardiac electrical leads
US5725525A (en) * 1993-03-16 1998-03-10 Ep Technologies, Inc. Multiple electrode support structures with integral hub and spline elements
US5549569A (en) * 1994-02-15 1996-08-27 Lawrence A. Lynn Ex vivo blood isolation system
US5759150A (en) * 1995-07-07 1998-06-02 Olympus Optical Co., Ltd. System for evulsing subcutaneous tissue
US5697916A (en) * 1995-11-21 1997-12-16 Stat Medical Devices Inc. Hypodermic dosage measuring device
US6071295A (en) * 1997-02-27 2000-06-06 Medivas Opcab, Inc. Device to hold an anastomotic site of coronary artery motionless and bloodless for the bypass operation
US6338710B1 (en) * 1997-02-27 2002-01-15 Medivas, Llc Device for stabilizing a treatment site and method of use
US5968017A (en) * 1997-10-14 1999-10-19 Merit Medical Systems, Inc. Pulse fluid infusion systems
US6203490B1 (en) * 1998-05-28 2001-03-20 KRAJíĈEK MILAN Myocardial stabilizer
US7398781B1 (en) * 1999-08-10 2008-07-15 Maquet Cardiovascular, Llc Method for subxiphoid endoscopic access
US7485624B2 (en) * 1999-08-10 2009-02-03 Allergan, Inc. Method for treating cardiac muscle disorders
US20080275371A1 (en) * 2003-09-04 2008-11-06 Ahof Biophysical Systems Inc. Vibrator with a plurality of contact nodes for treatment of myocardial ischemia
US20070023334A1 (en) * 2003-09-23 2007-02-01 Gambro Lundia Ab Apparatus, a system and a method relating to hemodialysis, hemodiafiltration, hemofiltration or peritoneal dialysis
US7914444B2 (en) * 2003-12-15 2011-03-29 Olympus Corporation Endoscope system and endoscope
US7621867B2 (en) * 2004-05-14 2009-11-24 Olympus Corporation Insertion device
US20080167621A1 (en) * 2005-05-16 2008-07-10 Wagner Gary S Multi-Barrel Syringe Having Integral Manifold
US20070255100A1 (en) * 2006-01-06 2007-11-01 Olympus Medical Systems Corporation Medical method and medical system conducted percutaneous or using naturally occurring body orifice
US20100191164A1 (en) * 2007-06-29 2010-07-29 Futoshi Sasaki Hemodialysis apparatus

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11304686B2 (en) 2011-06-17 2022-04-19 Koninklijke Philips N.V. System and method for guided injection during endoscopic surgery
US9393001B2 (en) 2011-07-29 2016-07-19 Olympus Corporation Operation method of endoscope
US10159586B2 (en) 2015-06-29 2018-12-25 480 Biomedical Inc. Scaffold loading and delivery systems
US10232082B2 (en) 2015-06-29 2019-03-19 480 Biomedical, Inc. Implantable scaffolds for treatment of sinusitis
US10278812B2 (en) 2015-06-29 2019-05-07 480 Biomedical, Inc. Implantable scaffolds and methods for treatment of sinusitis
US10857013B2 (en) 2015-06-29 2020-12-08 Lyra Therapeutics, Inc. Scaffold loading and delivery systems
US10973664B2 (en) 2015-12-30 2021-04-13 Lyra Therapeutics, Inc. Scaffold loading and delivery systems
US11172807B2 (en) 2016-05-23 2021-11-16 Olympus Corporation Endoscope device and endoscope system with deforming insertion portion wire
US10201639B2 (en) 2017-05-01 2019-02-12 480 Biomedical, Inc. Drug-eluting medical implants
US20220054118A1 (en) * 2020-08-20 2022-02-24 Satoshi AWADU Flexible endoscope insertion method for examining the lateral wall of the lumen or the lateral side of the organ

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