US20090254045A1 - Device for dispensing an injectable product in doses - Google Patents
Device for dispensing an injectable product in doses Download PDFInfo
- Publication number
- US20090254045A1 US20090254045A1 US12/417,204 US41720409A US2009254045A1 US 20090254045 A1 US20090254045 A1 US 20090254045A1 US 41720409 A US41720409 A US 41720409A US 2009254045 A1 US2009254045 A1 US 2009254045A1
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- United States
- Prior art keywords
- threaded rod
- threaded
- threaded nut
- locking arrangement
- casing element
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2492—Ampoule holder connected to rest of syringe via snap connection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Feeding And Watering For Cattle Raising And Animal Husbandry (AREA)
Abstract
A device for dispensing a product in doses including a casing element, a dosing device shiftable relative to the casing element in a dispensing direction, a setting device for setting the position of the dosing device, and a restoring element for returning the dosing device to a starting position, wherein a movement of the dosing device in the dispensing direction charges the restoring element.
Description
- This application is a continuation of U.S. Ser. No. 10/942,391 filed Sep. 16, 2004, which claims priority to German Patent Application No. 10343548.4 filed Sep. 19, 2003, the contents of which are herein incorporated by reference.
- The invention relates to devices and methods for dispensing, including devices and methods for dispensing, administering, injecting and/or infusing a medicinal product, including injectable medicinal products, such as insulin or hormone preparations, in doses. The application claims the priority of German patent application No. 103 43 548.4, filed on Sep. 19, 2003 with the German Patent and Trademark Office.
- Devices for dispensing, administering or injecting injectable products are well-known. Such devices may include a dosing means, some of which are restorable or resettable, but it may be difficult to restore the dosing means and, in some cases, it may not be possible at all.
- EP 0 614 386 B1 describes a device in which a toothed rack which acts on a piston arranged in a container for the dosing product is only provided with teeth over a part of its circumference. The teeth of the toothed rack cooperate with opposing teeth in such a way that the toothed rack can be shifted in discrete increments for the purpose of delivering the product but is prevented from being simply retracted. In order to be restored, the toothed rack is formed such that the teeth and the opposing teeth are disengaged by rotating the toothed rack by 90° and the toothed rack can then be manually retracted and moved to a starting position for a new, dosed delivery. Restoring the driven member requires the user to perform a number of movements in coordination. This, however, can lead to problems for a user who is perhaps not familiar with handling a somewhat complex mechanism, and therefore restrict the range of application of the device.
- A device for administering an injectable product in doses is known from
DE 10 046 279 A1, belonging to the Applicant, wherein a restoring spiral spring is provided which is secured when tensioned and is coupled to a drive unit by a release and can cause a restoring movement of the drive unit towards its dosing starting position. - It is an object of the present invention to provide a device for dispensing an injectable product in doses, in which it is possible to automatically restore or reposition a dosing device. In particular, the intention is to provide such a device in which a restoring element can be used in a number of restoring procedures and wherein the restoring element can be integrated into the device in a way which conserves as much space as possible.
- This object is addressed by providing a device for dispensing a product in doses comprising a casing element, a dosing device which can be shifted relative to the casing element, a setting device using which the position of the dosing device can be set, and a restoring element which uses a movement of the dosing device in a dispensing direction to generate a restoring force by which the dosing device can be returned to a starting position.
- In accordance with one embodiment of the present invention, the device for dispensing an injectable product, such as insulin or hormone preparations, in doses comprises a casing element or a mechanism holder which can accommodate component parts of a dosing mechanism or the complete dosing mechanism. A dosing device, for example a threaded rod, is mounted such that it can be shifted relative to the casing element and preferably in the casing element. An ampoule containing the injectable product to be dosed can be connected to the casing element and a particular amount of the substance contained in the ampoule can be dosed or selected for dispensing by shifting the dosing device relative to the casing element. The selected amount is then dispensed by actuating a triggering button. The position of the dosing device can be set or altered using a setting device, which, for example, can be rotated relative to the dosing device and/or casing element. A restoring element is provided in or on the device and can generate a restoring force which can automatically return the dosing device to its starting position (or another selected position) again after one or more dosing procedures, for example, to exchange a partially or completely emptied ampoule and replace it with a new, filled ampoule. In one embodiment the restoring element is preferably formed and arranged such that the force required to restore the dosing device is accumulated during a setting and/or dispensing procedure of the device and the force thus accumulated can be transferred to the dosing device after the restoring element has been released, in order to move it to a starting position.
- In one embodiment, the present invention comprises a device for dispensing a product in doses including a casing element, a dosing device shiftable relative to the casing element in a dispensing direction, a setting device for setting the position of the dosing device, and a restoring element for returning the dosing device to a starting position, wherein a movement of the dosing device in the dispensing direction charges or loads the restoring element.
- The “dosing device” is to be understood to be a device for adjusting, setting or selecting the amount of a substance to be dispensed or injected, including from an ampoule or other container. It should also be understood that it is possible for the dosing device to also be used to dispense the substance, e.g., by shifting the dosing device.
- In one embodiment, the restoring element is preferably a spring element such as a helical spring or a spiral spring which can be compressed by moving the dosing device in the dispensing direction and thus accumulates the force required to restore the dosing device. Using a helical spring is advantageous since it can be integrated into a dispensing device without a great need for space, for example by being arranged around a threaded rod or the like used as the dosing device. Additional, separate elements do not then have to be attached to the dispensing device, which simplifies the design of the dispensing device. In one embodiment, the restoring spring element is advantageously arranged coaxially with the dosing device, the casing element and/or at least partially within the casing element. In some embodiments, the restoring or spring element generates a force in an axial direction of the casing element and/or in the movement direction of the dosing device by being arranged, for example, between the dosing device and the casing element itself or between the dosing device and an element which can be inserted into the casing element, such as, for example, a sealing part as described below.
- In some embodiments, including in preferred embodiments, a safety mechanism is provided which prevents the dosing device from being restored or moved by the restoring element. This safety mechanism can, for example, be a switch or a rotational block such as described below.
- In some embodiments, a threaded engagement is preferably provided between the setting device and the dosing device, wherein the setting device is preferably arranged coaxially with the dosing device. The setting device can, for example, have an inner thread which can be engaged with the dosing device which for example is formed by a threaded rod with an outer thread. It is equally possible for the setting device to comprise an outer thread which can be engaged with an inner thread of the dosing device.
- If the dosing device comprises a thread which engages with a corresponding thread of the setting device, then it is advantageous to form the thread such that it is not self-locking, i.e., the thread pitch should be chosen such that the force applied to the dosing device by the restoring element is sufficient to move the dosing device towards a starting position.
- In one preferred embodiment, the dosing device can be secured against rotation relative to the casing element, during a dosing procedure, dispensing procedure, or other operation by the dosing device exhibiting a rotationally asymmetrical cross-section, such that a passage opening corresponding to the cross-section and arranged in an element which is mounted secured against rotation relative to the casing element can hold the dosing device in the casing element, secured against rotation. The dosing device can then still be freely moved through the this rotational block. If the element serving as the rotational block for the dosing device is released relative to the casing element, then the dosing device can also be moved and, in particular, rotated relative to the casing element. When the dosing device is secured against rotation, the position of the dosing device can then be altered by rotating the setting device coupled to the dosing device via a thread, in order to set a dosage of the substance to be dispensed for example from an ampoule. Advantageously, the setting device can be rotated relative to the casing element.
- Advantageously, in some embodiments, the setting device can be secured against rotation relative to the casing element and the dosing device can preferably be freely moved, in particular rotated, relative to the casing element when the setting device is secured against rotation. This enables the restoring element provided in accordance with the invention to return or retract the dosing device to a starting position, e.g., once the restoring element has been released. The dosing device can be coupled to the setting device via a threaded engagement, in which case the dosing device is screwed back when restored to the starting position by the force of the restoring element. It is equally possible for the threaded engagement to be released, which enables the dosing device to be returned to the starting position by the force generated or provided by the restoring element, in which position the setting device is coupled to the dosing device again by rotating the dosing device and/or the restoring device in order to re-establish a threaded engagement between these two devices. Other suitable coupling arrangements and coupling/decoupling operations could be used to engage the devices.
- In one embodiment, the rotational blocks of the dosing device and the setting device are preferably coupled such that in a first state the setting device can be freely moved and the dosing device is secured against rotation and, in a second state the dosing device can be freely moved and the setting device is secured against rotation. The term “secured against rotation” is to be understood as a holder, mounting structure or shape of the device in question which prevents said device from rotating relative to another device acting on said device. Thus, for example, in the case of a threaded engagement rotating one device coupled to the device secured against rotation causes the device secured against rotation to not rotate with the one device but to convert the rotational force into an advancing or retracting movement.
- In accordance with another embodiment and/or effect of the present invention, the invention relates to a system comprising a device as described above and a coupling device for an ampoule, into which an ampoule can be inserted or plugged or to which an ampoule can be connected generally, wherein the dosing device can be inserted into the interior of the ampoule, for example during or after the setting procedure, in order to displace a substance in the ampoule, the amount of the substance dispensed from the ampoule being determined by the insertion depth of the dosing device.
- In one embodiment, the ampoule coupling device is advantageously configured such that when an ampoule is plugged onto the dispensing device or connected to the dispensing device, the dosing device is secured against rotation and can be moved into or towards the ampoule by rotating the setting device. If the ampoule coupling is not coupled or connected to an ampoule, the rotational block on the dosing device is advantageously released, enabling the dosing device to be rotated back to a starting position by the restoring element.
-
FIG. 1 depicts an embodiment of the device in accordance with the invention, in an exploded view; -
FIG. 2 depicts the device ofFIG. 1 , cut open in the longitudinal direction; -
FIG. 3 is a cross-sectional view of the device shown inFIG. 1 , assembled in the starting position; -
FIG. 4 depicts the device shown inFIG. 3 , with an ampoule sleeve attached, in the starting position; -
FIG. 5 depicts the device shown inFIG. 4 , with the threaded rod extended; and -
FIG. 6 depicts the device shown inFIG. 5 , after the ampoule has been removed. -
FIG. 1 shows an embodiment of a device in accordance with the present invention, comprising amechanism holder 5 which serves as the casing element and comprises astopper 5′ at its front end, shown on the left inFIG. 1 , anabrasive disc 10 being attached to said stopper. Anabrasive disc 11 is arranged opposite theabrasive disc 10 and is fastened on a rotatingring 12. When assembled as shown inFIG. 3 , theabrasive discs FIG. 4 , such that therotating ring 12 can be rotated relative to themechanism holder 5. The threaded rod exhibits a threaded profile 8 a on the upper side shown inFIGS. 1 and 2 and on the lower side (not shown) and is flattened on the front side shown inFIG. 1 and on the opposite side, such that the threadedrod 8 can be guided in a mounting or passage opening 12 a of therotating ring 12 shown inFIG. 2 , which approximately corresponds to the cross-section of the threadedrod 8, enabling the threadedrod 8 to be mounted in therotating ring 12, secured against rotation. - In the embodiment shown, the
mechanism holder 5 comprises four passages 5 a through which theinsertion elements 4′ of the releasingpart 4 can be guided in order to be able to connect the releasingpart 4 to themechanism holder 5 or insert the releasingpart 4 into themechanism holder 5 secured against rotation. - A grating 4 a is provided on the surface of the releasing
part 4 facing away from theinsertion elements 4′ of the releasingpart 4 and can engage with a corresponding grating 3 a of the sealingpart 3 when the sealingpart 3 and the releasingpart 4 are abutting or lying on each other, which couples the sealingpart 3 and the releasingpart 4 such that a rotation can be transferred. Thepressure spring 2 arranged between the threadednut 1 and the sealingpart 3 causes the sealingpart 3 and the releasingpart 4 to tend to always be lying on each other when assembled as shown inFIG. 3 . - The threaded nut comprises tappets 1 a which engage with cavities 3 b of the sealing
part 3 and so establish a rotational block between the threadednut 1 and the sealingpart 3. An inner thread 1 b is provided in the interior of the threadednut 1 and can engage with the outer thread 8 a of the threadedrod 8, such that the threadedrod 8 mounted in therotating ring 12, secured against rotation, can be moved in the axial direction of the device, e.g., to the left in the representation shown inFIG. 1 , by rotating the threadednut 1. - In the starting position shown in
FIG. 3 , the sealingpart 3 is mounted, secured against rotation, in corresponding grooves 5 b of themechanism holder 5, viatappets 3′. - A
helical spring 7 serving as a restoring element is arranged at the rear end of the threadedrod 8, shown on the right inFIG. 2 , and when assembled is bounded or contacted on one side by the head of the threadedrod 8 and on the other side by an inner stopper of the threadednut 1. - A
mechanism lock 6 and adosing button cap 9 seal the mechanism and can serve as end stoppers. - In the starting position (shown in
FIG. 3 ), the releasingpart 4 and the sealingpart 3 are inserted far enough into themechanism holder 5 for thetappets 3′ provided as the rotational block to engage with the corresponding grooves 5 b of themechanism holder 5. In this position, the sealingpart 3 cannot be rotated relative to themechanism holder 5 and the threadednut 1 held together with the sealingpart 3 via the tappets 1 a which engage with the cavities 3 b of the sealingpart 3 is likewise secured against rotation relative to themechanism holder 5. In the starting position shown inFIG. 3 , the threadedrod 8 is in a rear position and can be rotated relative to themechanism holder 5, since theabrasive discs rod 8 is thus pushed backwards far enough so no force acting backwards is applied to the threadedrod 8 by thehelical spring 7, which could shift the threadedrod 8 even further backwards. - If an
ampoule sleeve 13 is plugged onto the device as shown inFIG. 3 , then theampoule sleeve 13 snaps in at the undercut 15 as shown inFIGS. 4 and 5 . The rotatingring 12 is pushed backwards—to the right in FIG. 3—such that theabrasive discs rotating ring 12, secured against rotation, to themechanism holder 5, which also secures the threadedrod 8, mounted in the passage opening 12 a, against rotation. Furthermore, theinsertion elements 4′ of the releasingpart 4 are pushed through the passages 5 a of themechanism holder 5, which likewise pushes the releasingpart 4 backwards together with the sealingpart 3. The sealingpart 3 is pushed backwards far enough for thetappets 3′ (serving as the rotational block with respect to the mechanism holder 5) to be pushed out of the corresponding grooves 5 b of themechanism holder 5, enabling the sealingpart 3 to be rotated relative to themechanism holder 5. This releases the threadednut 1, coupled to the sealingpart 3, relative to themechanism holder 5, which can then be rotated. - Rotating the threaded
nut 1 leads to an axial movement of the threadedrod 8, via the inner thread 1 b which is coupled to the outer thread 8 a of the threadedrod 8 now mounted, secured against rotation, by the rotatingring 12 which is secured against rotation. By continuing to rotate the threadednut 1, the threadedrod 8 can be shifted towards theampoule sleeve 13 until the threadedrod 8 is in a front position as shown inFIG. 5 , in which the maximum volume to be displaced or dispensed from the ampoule is set. Thehelical spring 7 arranged around the threadedrod 8 is maximally biased by shifting the threadedrod 8. - A dispensing procedure is triggered or actuated by pressing the
dosing button cap 9, which presses the threadedrod 8—which is extended forward in accordance with the desired dosage—onto a displacement body in theampoule 13 by which the substance stored in the ampoule is displaced and output from an ampoule opening, e.g., to be injected. - If the ampoule has been sufficiently emptied that it needs to be exchanged, then the threaded
rod 8 is situated in a front position as shown inFIG. 5 . If theampoule sleeve 13 is released from the device in accordance with the invention by means of apressure device 14, then thefront pressure spring 2 pushes the sealingpart 3, the releasingpart 4 and therotating ring 12 forwards again. Thus, the sealingpart 3 is secured against rotation via thetappets 3′ which engage with the corresponding grooves 5 b of themechanism holder 5, and the threadednut 1 is secured against rotation again. - Shifting the
rotating ring 12 forwards releases theabrasive disc 11 from theabrasive disc 10, i.e., theabrasive discs rotating ring 12 free and no longer secured against rotation, such that the threadedrod 8, mounted in therotating ring 12 in the mounting 12 a, can likewise be rotated. Thehelical spring 7 pressing onto the threadedrod 8 causes the threadedrod 8 to be rotated back in the axial direction of the device, as far as its starting position shown inFIG. 3 . It is thus no longer necessary, when exchanging an ampoule, for a user to manually rotate the threadedrod 8 back, which simplifies the handling of the device in accordance with the invention. - Instead of the coupling or operable connection formed by the
abrasive discs - In the foregoing description, embodiments of the present invention, including preferred embodiments, have been presented for the purpose of illustration and description. They are not intended to be exhaustive or to limit the invention to the precise steps and forms disclosed. Obvious modifications or variations are possible in light of the above teachings. The embodiments were chosen and described to provide the best illustration of the principals of the invention and its practical application, and to enable one of ordinary skill in the art to utilize the invention in various embodiments and with various modifications as are suited to the particular use contemplated. All such modifications and variations are within the scope of the invention as determined by the appended claims when interpreted in accordance with the breadth they are fairly, legally, and equitably entitled.
Claims (8)
1. A device for dispensing a product in doses comprising:
a casing element comprising a front dispensing end and a rear end;
an ampoule sleeve coupleable to the front dispensing end of the casing element;
a threaded nut for setting a dosage and arranged at the rear end of the casing;
a threaded rod arranged at least partly in an interior of the threaded nut, the threaded rod and the threaded nut comprising complementary threading such that in response to rotation of the threaded nut, the threaded rod moves in the axial direction, the threaded rod axially movable in one or more dosing procedure movements towards the front dispensing end;
a releasable locking arrangement for locking the threaded rod against rotation; and
a helical spring contained within the interior of the threaded nut and encircling the portion of the threaded rod arranged in the interior of the threaded nut, the helical spring acting between the threaded nut and the threaded rod, wherein the helical spring is in a relaxed state when the a rear end of the threaded rod is arranged in a starting position within the threaded nut and the threaded nut is proximate the rear end of the casing element, and the helical spring is biased when the rear end of the threaded rod is in a front position and the threaded nut is proximate the rear end of the casing element;
wherein, upon releasing the locking arrangement, the biased helical spring urges the threaded rod to rotate towards its starting position.
2. The device as set forth in claim 1 , further comprising another releasable locking arrangement for locking the threaded nut against rotation.
3. The device as set forth in claim 2 , wherein the another releasable locking arrangement comprises an axially movable engagement of the threaded nut with the casing element
4. The device as set forth in claim 2 , wherein said releasable locking arrangement and said another releasable locking arrangement are coupled such that in the starting position, the threaded nut can be rotated and the threaded rod is secured against rotation, and in the front position the threaded nut is secured against rotation and the threaded rod can be rotated.
5. The device as set forth in claim 1 , wherein the releasable locking arrangement comprises a pressure spring arranged at a front dispensing end of the casing element.
6. The device as set forth in claim 1 , wherein upon releasing the locking arrangement, the threaded rod rotates towards its starting position to a selected position.
7. The device as set forth in claim 1 , wherein upon releasing the locking arrangement, the threaded rod rotates to its starting position.
8. The device as set forth in claim 1 , further comprising a coupling device for releasably receiving the ampoule sleeve, wherein at least one of the releasable locking arrangement and the another releasable locking arrangement can be established or released by said coupling device.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/417,204 US20090254045A1 (en) | 2003-09-19 | 2009-04-02 | Device for dispensing an injectable product in doses |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEDE10343548.4 | 2003-09-19 | ||
DE10343548A DE10343548B4 (en) | 2003-09-19 | 2003-09-19 | Device for metered delivery of an injectable product |
US10/942,391 US7513889B2 (en) | 2003-09-19 | 2004-09-16 | Device for dispensing an injectable product in doses |
US12/417,204 US20090254045A1 (en) | 2003-09-19 | 2009-04-02 | Device for dispensing an injectable product in doses |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/942,391 Continuation US7513889B2 (en) | 2003-09-19 | 2004-09-16 | Device for dispensing an injectable product in doses |
Publications (1)
Publication Number | Publication Date |
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US20090254045A1 true US20090254045A1 (en) | 2009-10-08 |
Family
ID=34177852
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/942,391 Expired - Fee Related US7513889B2 (en) | 2003-09-19 | 2004-09-16 | Device for dispensing an injectable product in doses |
US12/417,204 Abandoned US20090254045A1 (en) | 2003-09-19 | 2009-04-02 | Device for dispensing an injectable product in doses |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/942,391 Expired - Fee Related US7513889B2 (en) | 2003-09-19 | 2004-09-16 | Device for dispensing an injectable product in doses |
Country Status (7)
Country | Link |
---|---|
US (2) | US7513889B2 (en) |
EP (1) | EP1516638B1 (en) |
JP (1) | JP2005087739A (en) |
CN (1) | CN100448494C (en) |
AT (1) | ATE454913T1 (en) |
AU (1) | AU2004205277B2 (en) |
DE (2) | DE10343548B4 (en) |
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US20070060887A1 (en) * | 2005-08-22 | 2007-03-15 | Marsh David A | Ophthalmic injector |
US20070293820A1 (en) * | 2006-05-17 | 2007-12-20 | Bruno Dacquay | Disposable Ophthalmic Injection Device |
US20090036846A1 (en) * | 2006-05-17 | 2009-02-05 | Bruno Dacquay | Ophthalmic Injection System |
US20100106083A1 (en) * | 2006-10-16 | 2010-04-29 | Alcon Research, Ltd. | Method of Operating Ophthalmic Hand Piece with Disposable End |
US20100211044A1 (en) * | 2006-05-17 | 2010-08-19 | Alcon Manufacturing, Lted. | Battery operated surgical hand piece with disposable end |
US8177747B2 (en) | 2009-12-22 | 2012-05-15 | Alcon Research, Ltd. | Method and apparatus for drug delivery |
US8372036B2 (en) | 2009-05-06 | 2013-02-12 | Alcon Research, Ltd. | Multi-layer heat assembly for a drug delivery device |
US8535268B2 (en) | 2010-12-22 | 2013-09-17 | Alcon Research, Ltd. | Device for at least one of injection or aspiration |
US8608708B2 (en) | 2009-10-16 | 2013-12-17 | Owen Mumford Limited | Injector apparatus |
US11167092B2 (en) | 2015-02-27 | 2021-11-09 | Novo Nordisk A/S | Drug delivery device with dose reset mechanism |
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DE102006038103B4 (en) * | 2006-08-14 | 2017-02-23 | Tecpharma Licensing Ag | Injection device with variable thread guide |
EP2077878B1 (en) * | 2006-09-15 | 2020-01-01 | TecPharma Licensing AG | Injection device comprising an improved delivery element |
US20080125712A1 (en) * | 2006-09-26 | 2008-05-29 | Alcon Manufacturing, Ltd. | Ophthalmic injection system |
US20080097390A1 (en) * | 2006-09-27 | 2008-04-24 | Alcon Manufacturing, Ltd. | Spring actuated delivery system |
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US20080281292A1 (en) * | 2006-10-16 | 2008-11-13 | Hickingbotham Dyson W | Retractable Injection Port |
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US9022970B2 (en) | 2006-10-16 | 2015-05-05 | Alcon Research, Ltd. | Ophthalmic injection device including dosage control device |
US20080234625A1 (en) * | 2006-10-16 | 2008-09-25 | Bruno Dacquay | Fuse Assembly For Single Use Medical Device |
WO2008071804A1 (en) * | 2006-12-15 | 2008-06-19 | Novo Nordisk A/S | A medical delivery system comprising a container and a dosing assembly with radially moving fastening means |
WO2008074897A1 (en) * | 2006-12-21 | 2008-06-26 | Novo Nordisk A/S | A syringe device |
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DE102007026083A1 (en) * | 2007-05-25 | 2008-11-27 | Haselmeier S.A.R.L. | injection device |
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US20090036842A1 (en) * | 2007-08-03 | 2009-02-05 | Raffi Pinedjian | Consumable Activation Lever For Injection Device |
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US11400218B2 (en) * | 2015-03-23 | 2022-08-02 | Sanofi-Aventis Deutschland Gmbh | Housing for an injection device and interconnection of housing components |
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- 2004-08-27 AU AU2004205277A patent/AU2004205277B2/en not_active Ceased
- 2004-08-31 DE DE502004010632T patent/DE502004010632D1/en active Active
- 2004-08-31 AT AT04020575T patent/ATE454913T1/en not_active IP Right Cessation
- 2004-08-31 EP EP04020575A patent/EP1516638B1/en not_active Not-in-force
- 2004-09-16 US US10/942,391 patent/US7513889B2/en not_active Expired - Fee Related
- 2004-09-16 JP JP2004269322A patent/JP2005087739A/en active Pending
- 2004-09-17 CN CNB2004100797617A patent/CN100448494C/en not_active Expired - Fee Related
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2009
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US4883472A (en) * | 1985-11-08 | 1989-11-28 | Disetronic Ag. | Injection device |
US5626566A (en) * | 1991-10-18 | 1997-05-06 | Novo Nordisk A/S | Large dose pen |
US6193698B1 (en) * | 1997-07-18 | 2001-02-27 | Disetronic Licensing Ag | System for locking a dosing button in a device for the adminstration of a product to be injected |
US5957896A (en) * | 1997-08-11 | 1999-09-28 | Becton, Dickinson And Company | Medication delivery pen |
US20020052578A1 (en) * | 2000-06-16 | 2002-05-02 | Moller Claus Schmidt | Injection device |
US20020111587A1 (en) * | 2001-02-15 | 2002-08-15 | Edgar Hommann | Injection device for injecting fluid |
US20050131355A1 (en) * | 2002-06-12 | 2005-06-16 | Fritz Kirchhofer | Injection or infusion device with refined surface |
US20050137571A1 (en) * | 2002-06-28 | 2005-06-23 | Edgar Hommann | Administering apparatus with a resettable activating block |
Cited By (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070060887A1 (en) * | 2005-08-22 | 2007-03-15 | Marsh David A | Ophthalmic injector |
US20070293820A1 (en) * | 2006-05-17 | 2007-12-20 | Bruno Dacquay | Disposable Ophthalmic Injection Device |
US20080021438A1 (en) * | 2006-05-17 | 2008-01-24 | Bruno Dacquay | Ophthalmic Injection Method |
US20090036846A1 (en) * | 2006-05-17 | 2009-02-05 | Bruno Dacquay | Ophthalmic Injection System |
US20100211044A1 (en) * | 2006-05-17 | 2010-08-19 | Alcon Manufacturing, Lted. | Battery operated surgical hand piece with disposable end |
US7815603B2 (en) | 2006-05-17 | 2010-10-19 | Alcon Research, Ltd. | Ophthalmic injection method |
US7871399B2 (en) | 2006-05-17 | 2011-01-18 | Alcon Research, Ltd. | Disposable ophthalmic injection device |
US7887521B2 (en) | 2006-05-17 | 2011-02-15 | Alcon Research, Ltd. | Ophthalmic injection system |
US8118790B2 (en) | 2006-05-17 | 2012-02-21 | Alcon Research, Ltd. | Battery operated surgical hand piece with disposable end |
US20100106083A1 (en) * | 2006-10-16 | 2010-04-29 | Alcon Research, Ltd. | Method of Operating Ophthalmic Hand Piece with Disposable End |
US8632511B2 (en) | 2009-05-06 | 2014-01-21 | Alcon Research, Ltd. | Multiple thermal sensors in a multiple processor environment for temperature control in a drug delivery device |
US8372036B2 (en) | 2009-05-06 | 2013-02-12 | Alcon Research, Ltd. | Multi-layer heat assembly for a drug delivery device |
US9415165B2 (en) | 2009-10-16 | 2016-08-16 | Owen Mumford Limited | Injector apparatus having a clutch to inhibit forward movement of the plunger |
US8608708B2 (en) | 2009-10-16 | 2013-12-17 | Owen Mumford Limited | Injector apparatus |
US10806865B2 (en) | 2009-10-16 | 2020-10-20 | Owen Mumford Limited | Injector apparatus having a clutch to inhibit forward movement of the plunger |
US11033690B2 (en) | 2009-10-16 | 2021-06-15 | Owen Mumford Limited | Injector apparatus having a clutch to inhibit forward movement of the plunger |
US11819668B2 (en) | 2009-10-16 | 2023-11-21 | Owen Mumford Limited | Injector apparatus having a clutch to inhibit forward movement of the plunger |
US8177747B2 (en) | 2009-12-22 | 2012-05-15 | Alcon Research, Ltd. | Method and apparatus for drug delivery |
US8535268B2 (en) | 2010-12-22 | 2013-09-17 | Alcon Research, Ltd. | Device for at least one of injection or aspiration |
US9592337B2 (en) | 2010-12-22 | 2017-03-14 | Alcon Research, Ltd. | Device for at least one of injection or aspiration |
US11167092B2 (en) | 2015-02-27 | 2021-11-09 | Novo Nordisk A/S | Drug delivery device with dose reset mechanism |
Also Published As
Publication number | Publication date |
---|---|
DE10343548B4 (en) | 2008-03-27 |
DE10343548A1 (en) | 2005-04-14 |
US7513889B2 (en) | 2009-04-07 |
JP2005087739A (en) | 2005-04-07 |
ATE454913T1 (en) | 2010-01-15 |
AU2004205277B2 (en) | 2009-04-09 |
AU2004205277A1 (en) | 2005-04-07 |
US20050065477A1 (en) | 2005-03-24 |
CN1597002A (en) | 2005-03-23 |
CN100448494C (en) | 2009-01-07 |
EP1516638B1 (en) | 2010-01-13 |
DE502004010632D1 (en) | 2010-03-04 |
EP1516638A1 (en) | 2005-03-23 |
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Legal Events
Date | Code | Title | Description |
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STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |